LOCUS       NZ_CP033336            20873 bp    DNA     circular CON 03-APR-2024
DEFINITION  Streptococcus pyogenes strain TSPY165 chromosome, complete genome.
ACCESSION   NZ_CP033336
VERSION     NZ_CP033336.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1812036)
  AUTHORS   Macias,O.R., Shah,B.J., Hanson,B., Sanson,M.A. and Flores,A.R.
  TITLE     Complete genome sequences of group A Streptococcus emm types
            frequently associated with antibiotic resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1812036)
  AUTHORS   Macias,O.R., Shah,B.J., Hanson,B., Sanson,M.A. and Flores,A.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-OCT-2018) Pediatrics, UTHSC/McGovern Medical School,
            6431 Fannin St., MSB 3.130, Houston, TX 77030, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2018
            Assembly Method :: Unicycler v. 0.4.6; Canu v. 1.7.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 263.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004124135.1-RS_2024_04_03
            Annotation Date                   :: 04/03/2024 02:58:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,798
            CDSs (total)                      :: 1,709
            Genes (coding)                    :: 1,656
            CDSs (with protein)               :: 1,656
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 53
            CDSs (without protein)            :: 53
            Pseudo Genes (ambiguous residues) :: 0 of 53
            Pseudo Genes (frameshifted)       :: 31 of 53
            Pseudo Genes (incomplete)         :: 23 of 53
            Pseudo Genes (internal stop)      :: 18 of 53
            Pseudo Genes (multiple problems)  :: 17 of 53
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:19:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 639735
            Orig. end                         :: 660608
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033336.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Anthony R. Flores, MD, MPH,
            PhD.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20873
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10873](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(765..785)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.95"
                     /tool="antismash"
     misc_feature    1659..1672
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            2046..2276
                     /locus_tag="EB817_RS03410"
                     /old_locus_tag="EB817_03415"
     CDS             2046..2276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /locus_tag="EB817_RS03410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03415"
                     /product="YkuJ family protein"
                     /protein_id="WP_002983885.1"
                     /transl_table=11
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFSNDPENG
                     PVFTLRDVEARESYSFDSIDLIAMEIYDLLY"
     gene            2403..3089
                     /locus_tag="EB817_RS03415"
                     /old_locus_tag="EB817_03420"
     CDS             2403..3089
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018000.1"
                     /locus_tag="EB817_RS03415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03420"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_002983887.1"
                     /transl_table=11
                     /translation="MDLSFLPKYWAYFNYGVLVTIMISVSVVFFGTLIGVLVTLIKRSH
                     VKPLTWVVNLYVWIFRGTPMVVQIMIAFAWMHFNNMPTIGFGVLDLDFSRLLPGIIIIS
                     LNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPQNAMRYVILPQAFKNILPALGNEFIT
                     IIKDSALLQTIGVMELWNGAQSVVTATYSPISPLLVAAFYYLMVTTVMAQLLAVLERHM
                     AQGGNH"
     gene            3089..3823
                     /locus_tag="EB817_RS03420"
                     /old_locus_tag="EB817_03425"
     CDS             3089..3823
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407690.1"
                     /locus_tag="EB817_RS03420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03425"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_002989107.1"
                     /transl_table=11
                     /translation="MTEAIISIKDLHKYYGHNEVLKGIDLDIMPGEVVVIIGPSGSGKS
                     TLLRTMNLLEVPTKGQIRFEGIDITDKKNDIFSMREKMGMVFQQFNLFPNMTILENITL
                     SPIKTKGMAKAEADKTALSLLDKVGLSEKAKAYPASLSGGQQQRIAIARGLAMDPDVLL
                     FDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGVIVEEG
                     SPNQLFDLTKEERTKDFLSRVL"
     gene            3972..5381
                     /locus_tag="EB817_RS03425"
                     /old_locus_tag="EB817_03430"
     CDS             3972..5381
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989109.1"
                     /locus_tag="EB817_RS03425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03430"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_129304582.1"
                     /transl_table=11
                     /translation="MVSVMWFRRDLRIDDQKALAHAIASQSPTLCVFQFNKEQLNLLHS
                     RNQSSFITSVLAFRKLLKCEGIDLYLMYGDLMTCFEQLLTQLKDWTDVYFNYDESGYGR
                     LRDQKAAQFFKKNGIAVHTYQDHYLHGSQEIINQSGQPYKVFTPYYRIWQNYPKETPIK
                     VELSQGRWLNLETPDDVLRTVESFKDEKYQDVATFDEASKQLNRFIQDQLAAYHANRDF
                     PAQLGTSRLSPFLRIGAIGIRTVYHAVRQAPNSLGQATFLKELSWRDFYNMVYVAYPDQ
                     KTQPIQKAFSQIEWVNNPDWFQLWKEGKTGYPIVDAAMLQLQKTGWMHNRLRMIVASFL
                     TKDLLCDWRLGEQYFQQQLIDYDAASNIGGWQWAASTGTDAVPYFRIFNPVTQGKRFDP
                     KGEFIKAYLPQLEHVPEKYLHEPWKMPKNLQESVSCIIGTDYPQPIVDHAKQREQAIAK
                     YEWAKEKAKIE"
     misc_feature    complement(5497..5508)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.16"
                     /tool="antismash"
     misc_feature    5526..5541
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.0"
                     /tool="antismash"
     gene            5559..7253
                     /locus_tag="EB817_RS03430"
                     /old_locus_tag="EB817_03435"
     CDS             5559..7253
                     /EC_number="5.4.2.-"
                     /GO_function="GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /locus_tag="EB817_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03435"
                     /product="phospho-sugar mutase"
                     /protein_id="WP_002989112.1"
                     /transl_table=11
                     /translation="MTYNEVYQEWLHNNDLSDDIKADLAAIKDNEAEIQDRFYKTLEFG
                     TAGLRGKLGAGTNRMNTYMVGKAAQALANTIIDHGPEAVKKGIAVSYDVRYQSRTFAEL
                     TCSIMAANGIKAYLYKGIRPTPMCSYAIRALGCISGVMITASHNPQAYNGYKAYWQEGS
                     QILDDIADQIAQHMAALTQYQEIKQMPFEKALDSGLVTYIDESIEEAYKKEVLGLTIND
                     TDIDKSVRVVYTPLNGVGNLPVREVLRRRGFENVYVVPEQEMPDPDFTTVGYPNPEVPK
                     TFAYSEKLGKAVDADILIATDPDCDRVALEVKNAVGDYVFLNGNKIGALLSYYIFSQRF
                     DLGNLPANPVLVKSIVTGDLSRAIASHYGIETVETLTGFKNICGKANEYDVTKQKNYLF
                     GYEESIGFCYGTFVRDKDAVSASMMIVEMAAYYKKKGQNLLDVLQTIYATFGYYNERQI
                     ALELEGIEGQKRIARIMEDFRQTPIASVAEMALDKTIDFIDGYQDFPKQNCLKFYLDDG
                     SWYALRPSGTEPKIKFYLYTIGQTQENSATKLDAIEAACRTKINQVN"
     gene            7461..8315
                     /locus_tag="EB817_RS03435"
                     /old_locus_tag="EB817_03440"
     CDS             7461..8315
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922486.1"
                     /locus_tag="EB817_RS03435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03440"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_010922486.1"
                     /transl_table=11
                     /translation="MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPA
                     SQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHI
                     NDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVI
                     IGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKD
                     GAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRS
                     THK"
     misc_feature    complement(8382..8398)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.76"
                     /tool="antismash"
     misc_feature    8391..8405
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.26"
                     /tool="antismash"
     gene            8468..9808
                     /gene="xseA"
                     /locus_tag="EB817_RS03440"
                     /old_locus_tag="EB817_03445"
     CDS             8468..9808
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /locus_tag="EB817_RS03440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03445"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_129304584.1"
                     /transl_table=11
                     /translation="MADYLTVTHLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDESAVIQATMWAGVYKKLGFDLEEGMKINVIGRVQLYEPSGSYSIVIEKAEPDGIG
                     ALALQFEQLKKKLTAEGYFEQKHKQPLPQFVSKIGVITSPSGAVIRDIITTVSRRFPGV
                     EILLFPTKVQGDGAAQEVVANIRRANQREDLDLLIVGRGGGSIEDLWAFNEEIVVQAIF
                     ESKLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDLMSWIVERQNRSYQA
                     CLRRIKQRQEWVAKLSQSVIFRQPERLYDAYLQKIDRLSMTLMNTMKDRLSSAKENKVQ
                     LDHALANSQLQTKIERYQDRVATAKRLLMANMTNQYDSQLARFEKAQDALLSLDASRII
                     ARGYAMIEKNQALVASVSQITKGDQLTIKMRDGQLDVEVEDVKNENI"
     gene            9786..10001
                     /locus_tag="EB817_RS03445"
                     /old_locus_tag="EB817_03450"
     CDS             9786..10001
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983901.1"
                     /locus_tag="EB817_RS03445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03450"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_002983901.1"
                     /transl_table=11
                     /translation="MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKEL
                     QKTLQAAEKTLVKVMQADGTEVDMDD"
     gene            10001..10873
                     /locus_tag="EB817_RS03450"
                     /old_locus_tag="EB817_03455"
     CDS             10001..10873
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888744.1"
                     /locus_tag="EB817_RS03450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03455"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_003056941.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.5e-51, bitscore:
                     170.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKLARIDEAIRRYYKTTSNGVSEELIDAILYSVDSGGKRIRPLI
                     LLEMIEGFGVSLQNAHFDLAAALEMIHTGSLIHDDLPAMDNDDYRRGRLTNHKQFGEAT
                     AILAGDSLFLDPFGLIAQAELNSEVKVALIQELSLASGTFGMVGGQMLDMKGENQALSL
                     PQLSLIHLNKTGKLLAFPFKAAALITEQAMTVRQQLEQAGMLIGHAFQIRDDILDVTAS
                     FEDLGKTPKKDLFAEKATYPSLLGLEASYQLLTESLDQALTIFQTLESDVGFKPQIITK
                     LIEGLRLNA"
     gene            10866..11693
                     /locus_tag="EB817_RS03455"
                     /old_locus_tag="EB817_03460"
     CDS             10866..11693
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /locus_tag="EB817_RS03455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03460"
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="WP_003056952.1"
                     /transl_table=11
                     /translation="MPKERVDVLAYKQGLFETREQAKRGVMAGLVVSVINGQRYDKPGD
                     KIDDGTELKLKGEKLKYVSRGGLKLEKGLHVFGVSVANQIGIDIGASTGGFTDVMLQDG
                     AKLVYAVDVGTNQLVWKLRQDPRVRSMEQYNFRYAQPEDFNEGQPVFASIDVSFISLSL
                     ILPALHNVLSDQGQVIALIKPQFEAGREQIGKKGIVKDKQIHEKVIQKVMDFASGYGFT
                     VKGLDFSPIQGGHGNIEFLAHLAKSQTPETLAPHLIQKVVAKAHKEFEKHEKE"
     gene            11680..12150
                     /locus_tag="EB817_RS03460"
                     /old_locus_tag="EB817_03465"
     CDS             11680..12150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983907.1"
                     /locus_tag="EB817_RS03460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03465"
                     /product="arginine repressor"
                     /protein_id="WP_002983907.1"
                     /transl_table=11
                     /translation="MKKSERLELIKKMVLTHPIETQHDLLRLLAEHGLELTQATISRDM
                     NEIGIVKIPSGSGRYIYGLSQDSGKKIVQGPRSIKSTILAVSDKTKGLEQHLYLKVVPG
                     NSKLIKRYLLADFSKAIFSLIADDDSLLLIAKSPSEADMIRQEILLWMQGIT"
     gene            12172..13833
                     /gene="recN"
                     /locus_tag="EB817_RS03465"
                     /old_locus_tag="EB817_03470"
     CDS             12172..13833
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051804.1"
                     /locus_tag="EB817_RS03465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03470"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_002983909.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIDEISLNFENGMTVLTGETGAGKSIIIDAMNMM
                     LGARASTEVIRRGANKAEIEGFFSVDATPELVACLESSGIAMEEELIIRRDIFANGRSV
                     SRINGQMVNLATLKQVGQFLVDIHGQHDQEELMRPQLHQQILDAFGDKAFEQLKENYQL
                     IFDRYKSLRRQVIDKQKNEKEHKDRIDMLAFQIAEIEAAALSRGEDDRLNQERDRLMNH
                     KQIADTLTNAYVMLDNDDFSSLSNIRSSMNDLLSIEQFDSEYKGMSTSISEAYYILEEV
                     SKQLSDTIDQLDFDGGRLQEIEFRLDTLNSLTRKYGGNVNDVLDYYDNIIKEYQLLTGD
                     DLSSGDLESELKALEKQLVAAATNLSERRHQLAEQLEAEIKAELKELYMEKADFKVHFT
                     TSKFNRDGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISRKEDKTSIVFD
                     EVDTGVSGRVAQAIAQKIYKIGRHGQVLAISHLPQVIAIADYQYFISKESKEESTVSKV
                     RLLTPEERVEEIASMIAGTDMTQAALTQARELLAKH"
     gene            14005..14955
                     /locus_tag="EB817_RS03470"
                     /old_locus_tag="EB817_03475"
     CDS             14005..14955
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285633.1"
                     /locus_tag="EB817_RS03470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03475"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_129304586.1"
                     /transl_table=11
                     /translation="MTSKKACLSSIIVLASLTCGNDTVSANHLSATGDKFDDCSTLVEK
                     DVAPKDELEMLAWSSSQTTDDADRDYEDFLDDDSFISQNETDKMFENLTDDRLLNELDE
                     LDEENEEDEEDEEDTIEPEQNVIMPSDDELFDLTDAVETRLTVSSAPHLEAELPKPHLR
                     SLSDTALRSGEIRGHLDNKLDALSVTATKLALTMAQKFDLTTHVYSIGESFSEVLAAHY
                     EDRKAESAFSKKKRFHLPIATPDVVIEELRRLVSSIGSSKEDVSVPYSRKLGMAVAKRK
                     IALPQTGEGFSYYPVLLGLMILGLTPIMIPKKINN"
     gene            15183..16022
                     /locus_tag="EB817_RS03475"
                     /old_locus_tag="EB817_03480"
     CDS             15183..16022
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264715.1"
                     /locus_tag="EB817_RS03475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03480"
                     /product="DegV family protein"
                     /protein_id="WP_002989125.1"
                     /transl_table=11
                     /translation="MGTIKIVTDSSITIEPELIKALDITVVPLSVMIDSKLYSDNDLKE
                     EGHFLSLMKASKSLPKTSQPPVGLFAETYENLVKKGVTDIVAIHLSPALSGTIEASRQG
                     AEIAEAPVTVLDSGFTDQAMKFQVVEAAKMAKAGASLNEILAAVQAIKSKTELYIGVST
                     LENLVKGGRIGRVTGVLSSLLNVKVVMALKNDELKTLVKGRGNKTFTKWLDSYLAKNSH
                     RPIAEIAISYAGEASLALTLKERIAAYYNHSISVLETGSIIQTHTGEGAFAVMVRYE"
     gene            16015..16857
                     /locus_tag="EB817_RS03480"
                     /old_locus_tag="EB817_03485"
     CDS             16015..16857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635578.1"
                     /locus_tag="EB817_RS03480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03485"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_032460551.1"
                     /transl_table=11
                     /translation="MNNRHLFSGIFFFVISLCLAFLLLNIIIPKSNSRLKKSDFLKKEQ
                     VAIQYVAIGDSLTEGVGDLTHQGGFVPLLTNDLSEYFKANVNHQNYGVSGDTSQQILDR
                     MIKQKQVQLSLKKADIMTLTVGGNDVMAVIRKNLADLQVSSFRKPARQYQKRLRQIIEL
                     ARKDNKDLPIFILGIYNPFYLNFPELTDMQKVIDDWNTKTKEVVGEYDRVYFVPINDLL
                     YKGINGQEGIVHSSGDQTTIVNDALFTGDHFHPNNTGYQIMSNAVMEKIKKHEKKIKP"
     gene            16835..17422
                     /locus_tag="EB817_RS03485"
                     /old_locus_tag="EB817_03490"
     CDS             16835..17422
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /locus_tag="EB817_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03490"
                     /product="YpmS family protein"
                     /protein_id="WP_002989129.1"
                     /transl_table=11
                     /translation="MKKKSNLNWWKWSFLCLLAFNTAFLMVIASRLIQVREPESELIAK
                     KPVKNIKIGTFVTTREQLNETVASYLKDYQTKKMSYKFYATSSSILFEGTYQLLGYEVP
                     LYIYFQPHRLENGAVQLQVISFSVGTLPLPEKDVLQYLKSSYKLPSFVKVMPNQSAIVV
                     NLQDIQNDAKVYLKAKKIDLFNDEISFNIYKK"
     gene            17521..17796
                     /locus_tag="EB817_RS03490"
                     /old_locus_tag="EB817_03495"
     CDS             17521..17796
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="EB817_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03495"
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_002983920.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSTIEAFLAEGEKVQL
                     IGFGNFEVRERAARKGRNPQTGAEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(17885..19027)
                     /locus_tag="EB817_RS03495"
                     /old_locus_tag="EB817_03500"
     CDS             complement(17885..19027)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051793.1"
                     /locus_tag="EB817_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03500"
                     /product="site-specific integrase"
                     /protein_id="WP_003051793.1"
                     /transl_table=11
                     /translation="MWIEETDNGKFKFRENYKDPYTGTWKPVSVTMEKDNSRAYKAARK
                     ILEQKITEKIAQLKASELLFTELLDEWWAFYKKELKRSSVASLRGNIEEIRETFGIGVK
                     VVNIDPKYVQNYLDNLDCSRNKKERNKSMLNLAFDYAVGLDIIQDNPARRAKLPRVKKT
                     LEDWKKAEEKYLEEDEIKPLLKELYRRPSTYRLGLLAEFISLNGCRIGEAVSIEPCNYE
                     SKSRILQLHGTFDHTEGYRNGEKTAPKTLASYRETIMTSRELEILQELEFMNELEKNTN
                     HRYRDMGYLFTTKNGVPIQTNSFNLALKKANERLEDPITKKLTSHIFRHTLISRLAENN
                     VPLKSIMERVGHADAKTTAQIYTHVTKKMKSSVADIMENY"
     gene            complement(19151..19669)
                     /locus_tag="EB817_RS03500"
                     /old_locus_tag="EB817_03505"
     CDS             complement(19151..19669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922481.1"
                     /locus_tag="EB817_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03505"
                     /product="HIRAN domain-containing protein"
                     /protein_id="WP_010922481.1"
                     /transl_table=11
                     /translation="MAKVIFQDNFLLMGTNYHEKEANKVMAEIGKKSPYWDKDKDFISD
                     YIKSNFKDIYKYYRVSTKDVEIVREPLNRHDPNAIKVMVNKTFVGYFPADLAKRLTPYV
                     KKSSHYQMEATLTGRGGQYKTLKNDLKTVVTKKKDITYKLRLTILKVDRVSKSKNAGLL
                     ESIASWFLN"
     gene            complement(19681..20436)
                     /locus_tag="EB817_RS03505"
                     /old_locus_tag="EB817_03510"
     CDS             complement(19681..20436)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922480.1"
                     /locus_tag="EB817_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03510"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_010922480.1"
                     /transl_table=11
                     /translation="MEQLGDRIRKLREGRNMTQTELSEILGMKTYTTVSKWEKNENFPK
                     GKDLKKLAEIFNVTSDYLLGLTDSKLGKITIQNEQPEIVSIYNQLEQPRQEKVLNFANE
                     QLEEQNKTVSIFDKKSEETEDYITDYVEGLVAAGLGAYQEDNLHMKVKLRSDDVPDEYD
                     TIAKVAGDSMEPLIQDNDLLFIKVSSQVDMNDIGIFQVNGKNFVKKLKRDYDGAWYLQS
                     LNKSYEEIYLSKDDDIRTIGEVVDIYREY"
     misc_feature    20532..20547
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.59"
                     /tool="antismash"
     misc_feature    20538..20551
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    20539..20552
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            20638..20850
                     /locus_tag="EB817_RS03510"
                     /old_locus_tag="EB817_03515"
     CDS             20638..20850
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922479.1"
                     /locus_tag="EB817_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EB817_03515"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010922479.1"
                     /transl_table=11
                     /translation="MVTIAELRAKHNKMSQRELAKELGVTQTSISNWEKDQTKISGEYL
                     ISLALFFDVSTDDILGINKQATQKF"
ORIGIN
        1 agaacttgta agaacatgtg catgacgtca ggatgggctt tttccacctc atctaagaga
       61 ataagtgaat atggattgcg acgaacttgt tcggttagct gtccagcttc ttcatagccg
      121 acataacctg gaggagcccc gactaatttg gcgacagcgt gtttttccat gtattcggac
      181 atgtcaaagc gaatcatatt gtttgtcgaa ccaaagagtt caatggctag ttgtttagac
      241 aattcagttt taccaacccc agtcggtcca acgaataaga aagaaccaat agggcgattt
      301 ggagttccta atcccacacg gttacgacga atagccttag cgattttatc aacagcatcg
      361 tcttgcccga tcacgtgtgc tttcagatca ttggctaagt ttacgagttg agactgttcc
      421 ttttctttta agtccccaac tggaatatta gttttttgct ctacaatagc ttcaatggtt
      481 ttttcagtaa tgatgggaat atcttgctca tcgacttttt gagcctgcat ttctttgtat
      541 tttgtaattt gatcgcggaa ataagctgcg cgttcatagt cttcgtctcg agtagcttgc
      601 gccttgagat tctcagcttc aataagacgt ttgtcaattt ctttaggatc aacaaagttg
      661 agggttagat tcattttgga accagcttcg tccagaagat caatagcctt atcaggaaga
      721 aaacggtctt gaatatagcg gttagataaa tgagcggcag cttcaatagc ggctgggcta
      781 tatttgacat gatgatagtc ttcgtatttc ggttggatac cttttaaaat cgtgatggtt
      841 tcctcaacag aaggttcatc aactttaacg ggttgcatac gtcgttctaa ggcagcgtct
      901 ttttcaataa tacggtattc atttaatgta gtagcaccaa cgagttgcaa ctcaccacgg
      961 gccaaggctg gttttaaaat attaccagca tccatattgc cgtctcctgc agaaccagca
     1021 ccgacaatct catgaatttc atcaataaag agaatcacat ccttgcgatt gcgaatttct
     1081 tccattaatt tttgcatgcg ctcttcaaac tgaccacgga tacctgttcc ctgaacgagg
     1141 ctaaccacat caagacgaat cacttgcttg ccttggagtt tttgaggaac agtaccatca
     1201 ataatttttt gagccaaacc ttctacaaca gcagttttac caactccagg ctcaccaatt
     1261 agcacaggat tatttttagt acggcggttg aggatctcga taacgcgtgt aatctcttcg
     1321 tcacgaccaa taacaggatc aatattacca tttcttgcaa tatctgtgac attaatccca
     1381 aactcttcta ataagccctt tgcttgctga tttggtgttt gtggctgagc aggtcgttgt
     1441 ccgttgtagt taccaccata gcgtcctccg ccatttccat tttgccctgc ctgagtaggt
     1501 ggggtatttg gaagattacc aaaagctcta aaattattca aatcaccaaa aaagtcatca
     1561 aagaaaggac ttgtggatct atcttgtgct ctatatcctg gggttaggcc atttaaaata
     1621 gaattggcag gatcggattt catgatttga taacaatttt gacagagatc aacctgtctt
     1681 tgttttccat taacacttgt ataaagatga atagtagatt cgtttaaatt acaattttga
     1741 cacagcataa tatacctccg agggtttatc taaaagtcaa agtcatttag tcaaaaatgg
     1801 tcaaacttta tattcatatt atagcaccac ggcttgggaa atcaagtaaa aagtttatcg
     1861 ctttagcgtt agcttttaga gagtaacatg acagagtaac tttattaagt ttccaatgag
     1921 caaatgttta aaatcattga aaagagtaaa aaaagtaaaa tatcaataaa tatattactt
     1981 tccttgttag tttcccttgt tttgtgttaa aataagaggg ataaaaaacg aataggagaa
     2041 acgaaatgga atcacatttg gtgagaatca tcaatcgttt ggagttgatg gtgacagatg
     2101 gcggtaatct caagcgaaat tttgaacgcg atggtgttgt tgttgcagaa gttgcctttt
     2161 caaatgatcc tgaaaatgga cctgttttca cattgcgtga tgttgaagcg cgtgagtcat
     2221 attcctttga tagcattgac ttgattgcaa tggaaatcta cgatttatta tattaagctt
     2281 gacatagtaa agagacttgc ctgaggcagg tttttttatt gtcaaaaagt attgtattaa
     2341 tattcatcag atggtataat tatctttatt gtaatgaacc taggacttat gaggagatat
     2401 aaatggattt gtcatttttg cccaaatact gggcctactt taactacggt gtacttgtca
     2461 ccattatgat ttcagtcagc gttgtctttt ttggaaccct tattggtgtc ttggtaaccc
     2521 tgattaagcg tagtcatgtg aagccgttga cctgggtcgt taatctttac gtttggatct
     2581 ttcggggaac acctatggtg gttcaaatca tgattgcctt tgcttggatg cattttaaca
     2641 atatgcctac tattggtttt ggggttttag acttggactt ttcaagacta cttcctggaa
     2701 ttattatcat ttcattgaat agcggtgctt atatttcaga aattgttaga gcaggtattg
     2761 aggctgtacc aaaagggcaa ttagaagcag cttattcact aggtattcgt cctcaaaatg
     2821 ccatgcgtta tgtgattttg cctcaggcct ttaaaaatat tttgccagcc ttaggaaatg
     2881 aatttattac cattattaag gatagtgctc ttttacaaac cattggagtg atggaacttt
     2941 ggaatggtgc ccaatcagtg gtaacggcta cttattctcc aatttcccct ttactggtgg
     3001 ctgcttttta ctacttaatg gtcacaacag tgatggcaca gttattggca gtcttagaac
     3061 gtcacatggc gcaaggaggt aatcattgat gactgaggcc attatttcaa ttaaagactt
     3121 gcacaagtat tatgggcaca atgaagtgct taagggaatt gatttagaca ttatgccagg
     3181 agaggttgtg gtgattattg gcccttctgg ttctggaaaa tcgaccttac ttcgaaccat
     3241 gaatcttttg gaagtaccaa ctaagggaca gattaggttt gaggggattg atattaccga
     3301 taagaagaac gatattttca gcatgcgtga aaaaatggga atggttttcc agcagtttaa
     3361 cctctttccc aatatgacta ttttagaaaa tatcacttta tcgccaatca aaactaaggg
     3421 aatggctaaa gcagaggctg acaaaacagc cttgagcttg ttggacaaag ttggattatc
     3481 agaaaaagcc aaggcttatc ctgctagtct ttctggtggg caacagcagc ggattgcgat
     3541 tgcgcgtgga ctggctatgg atccagatgt tttactcttt gatgaaccaa cttcagctct
     3601 agacccagaa atggtgggtg aggtcttggc tgtcatgcaa gatttggcta aatctgggat
     3661 gactatggtt attgtgactc atgaaatggg ctttgctaaa gaagtcgcag accgtgtgat
     3721 ttttatggat ggcggcgtta ttgtggaaga aggaagtcct aaccaacttt ttgatctgac
     3781 taaagaagag cgtacaaaag attttttgag tagagtatta taaatctgtt ctatgaatta
     3841 taaaaggaag tcctaaatga tttaggactt ccttttataa tttgctaagg cattttatag
     3901 gagattactt ttctttttgt taaaataaaa agaaatagtt gcattatttg catagaagaa
     3961 agggatctgt tatggtttca gtgatgtggt ttcgtagaga tttaaggatt gatgatcaaa
     4021 aagctttagc tcatgctatt gctagtcaat caccaacctt atgtgtgttt caatttaaca
     4081 aggagcaatt aaatctgcta catagtcgga atcaatctag ttttattact agcgttttgg
     4141 cttttagaaa gttattaaaa tgtgaaggta ttgacttata tctaatgtat ggagacttaa
     4201 tgacctgttt tgagcaatta ttgacacaat taaaagactg gacagatgtg tattttaact
     4261 atgatgaatc tggatatggt cgtttacgtg atcaaaaagc agcacaattt ttcaaaaaaa
     4321 atgggattgc cgttcatacc taccaagatc actatttaca tggtagtcaa gagatcatta
     4381 accaatcagg tcagccttat aaagttttta cgccctacta taggatttgg caaaattatc
     4441 cgaaagagac tcctattaaa gtagaactat cgcaaggcag gtggttaaat cttgagacac
     4501 cagatgatgt tttaaggact gttgagagct ttaaagatga aaaatatcag gatgttgcaa
     4561 cttttgatga agcgtcaaaa caactaaatc gatttattca agaccaatta gcagcttatc
     4621 acgctaatcg agattttcca gcgcagctag ggacgagtcg gttgtctcct tttttaagaa
     4681 taggagctat tggcattcgc acggtatatc acgctgtgcg tcaagcacca aatagtctag
     4741 ggcaagctac ttttttaaaa gaattatctt ggagagactt ttacaatatg gtctatgtgg
     4801 cttatcctga tcagaaaact cagcctatcc aaaaagcctt ttctcaaatc gaatgggtta
     4861 ataatcctga ctggtttcag ttgtggaaag aaggtaaaac gggttaccct attgttgatg
     4921 ctgccatgct tcagttacaa aagacaggat ggatgcataa tcgtttacga atgatagtag
     4981 cttctttttt aactaaagat cttttatgtg attggcgttt aggagagcag tattttcaac
     5041 aacaactaat tgattatgat gctgccagta atatcggagg atggcagtgg gctgcttcca
     5101 ctggaacaga tgctgttcct tattttagaa tatttaatcc tgttactcaa ggtaagcgct
     5161 ttgatcccaa aggcgagttt attaaagcgt atttgcctca actagaacac gttccagaga
     5221 agtatctcca cgaaccgtgg aagatgccaa aaaaccttca agagagtgtg tcctgtatta
     5281 ttggcacaga ctatcctcaa ccaattgtcg atcatgctaa acaacgtgaa caagctattg
     5341 caaagtatga gtgggcaaaa gaaaaagcaa aaatagaatg actgttctca ttataagagt
     5401 ttaaacaaaa agttatcatg aattaagatt atttaattta aaaaataagt tgactttatt
     5461 tagattattt gatactattc agttgtctcc cttagagaaa gcgatttctt gttttggagc
     5521 tgatttttac catttggtct tagaatagga tgagtaatat gacttacaac gaggtatatc
     5581 aagaatggtt gcacaataat gatcttagtg atgatattaa agcagattta gcagccataa
     5641 aagacaatga ggctgagatt caagatcgtt tttacaaaac acttgaattt ggaacagcag
     5701 ggctaagagg aaaacttgga gcaggcacca atcgcatgaa tacctatatg gttggtaagg
     5761 cagcacaagc tttagctaat actattattg atcatggacc tgaagcagtt aaaaagggca
     5821 ttgcggttag ttatgatgtt cgctatcaat ctagaacatt tgcagaatta acatgctcta
     5881 ttatggcagc taacggtatt aaggcgtacc tttataaagg gattcggcca acaccaatgt
     5941 gttcgtacgc tattcgtgct ttgggatgta tctctggtgt tatgattacg gctagtcaca
     6001 atccccaagc ttacaatggt tacaaagctt attggcaaga aggttctcaa attttggatg
     6061 acattgcgga tcaaattgca caacacatgg ctgcactaac tcagtatcag gaaatcaaac
     6121 aaatgccttt tgaaaaggct ctggacagtg gacttgttac ttatattgat gagagtattg
     6181 aagaagcata taaaaaagaa gtgcttggtt taacgattaa tgatactgac attgataagt
     6241 cagtccgagt agtctatacc cctttaaatg gtgttgggaa tctaccagtg cgtgaggttt
     6301 taagacgccg cggttttgaa aatgtttatg tggtacctga gcaggaaatg cccgatcctg
     6361 attttacaac agttggctat cctaatcccg aagtccctaa aacttttgca tattcagaaa
     6421 aattaggtaa ggcagttgat gctgatattt tgattgcaac tgatccagat tgtgaccgtg
     6481 tggctttaga agttaaaaac gcagtcggtg actatgtttt tctcaatggc aataaaatcg
     6541 gagcgctttt atcttactat atcttttcac aacgatttga cttaggtaat ttaccggcta
     6601 atcctgtttt agtgaaatcc attgtaacag gagacttgtc acgggctatt gctagccatt
     6661 atggtattga aaccgttgaa acattgactg gttttaagaa tatttgtggc aaggcaaacg
     6721 aatatgatgt gacgaaacag aaaaactatc tgtttggtta tgaagaaagt attggttttt
     6781 gctatggcac ttttgttcgt gacaaagacg ctgttagcgc ctctatgatg attgtagaaa
     6841 tggcagctta ctacaagaaa aaggggcaga atttactaga tgttttgcag actatttatg
     6901 cgacatttgg gtattataat gaacgtcaaa ttgccttgga gcttgagggg atagaaggac
     6961 aaaaacgcat tgcgaggata atggaagatt tcagacagac accaatagct agtgttgcag
     7021 aaatggcgtt agataagaca attgatttta ttgatggcta tcaagatttt ccaaagcaaa
     7081 actgtctcaa attttacttg gatgatggtt cttggtatgc acttagacca tcaggaacag
     7141 agcctaaaat aaaattttat ttatatacta ttggccaaac acaagaaaat agtgcaacaa
     7201 aattagatgc tattgaagca gcgtgtcgca caaaaataaa tcaggttaat taaacatcaa
     7261 aaatggataa cacttttaca ctatttttcc atataaacaa ctacaaaagg aggtgagact
     7321 tttaggcacc ttctttttct tgtaggtgcc actaatcaat ttaatcgact caaaccaata
     7381 ctaaaaaata agtaagagta taaagaacag gcatctattt ttttgttata atagaaaaat
     7441 gaaattaaag ggagatgtca atgacagaac taattgatgg taaagcctta gctcaaaaga
     7501 tgcagcaaga gttagcagct aaagtcaaca atctaaaaca aaaaaaagga attgtaccag
     7561 gcttagccgt tattcttgta ggtgatgatc ctgctagtca ggtatatgtc cgtaataaag
     7621 agcgtgcagc tcttactgta ggttttaaaa gtgagaccgt tagattatca gaattcattt
     7681 gtcaagaaga gcttattgca gtaatcgaac gttacaatgc agataacact attcatggta
     7741 ttttagtgca gctacccctg ccaaatcata ttaatgataa aaaaattatt ctcgccattg
     7801 atcccaaaaa agatgtggat ggttttcacc cgatgaatac aggtcatctt tggtcaggac
     7861 gtcccttgat ggttccttgt actccatcag ggattatgga attgcttcga gaatataatg
     7921 ttaaccttga aggtaaacat gccgtcatta ttggcagatc gaatatcgtt ggaaaaccaa
     7981 tggcacagct cttactggac aaaaatgcaa cagtcacgtt gacacattca agaacacgtc
     8041 aattagaaga agtatgtcgc tgtgcagatg tgttgattgt ggcaatcgga caaggtcatt
     8101 tcataacaaa acaatatata aaagatggtg cgatagtgat tgatgtggga atgaaccgtg
     8161 atgataatgg caagctaatt ggagatgtgg cctttgatga ggtggcagaa gttgcagcga
     8221 aaatcacccc tgtaccagga ggtgtcggtc ctatgacgat tgctatgttg ctagagcaaa
     8281 cttatcaatc tgctctccgt agtactcata aatagttata attagacaat tcaacataag
     8341 agaatataag aagtcagcaa tggcttcctt ttttgttttt ctgctcacta tttattcaga
     8401 aaaatggtat aattgcatta gtatgcaaag ggactatgtc aggtccaact aagtgaaagg
     8461 tggcttgatg gcagattatt taaccgtcac tcatttgacg aaatatttaa aattaaaatt
     8521 tgaccgtgac ccttatttgg aacgggttta tctgactggt caagtgtcca attttcgaaa
     8581 acgaccgact catcaatatt tttccttaaa agatgaaagt gctgtgattc aagccaccat
     8641 gtgggcagga gtctataaaa aactaggatt tgacctagaa gaaggcatga aaattaatgt
     8701 gattgggcga gtccaacttt atgaaccgag tggttcctat tctatcgtga ttgaaaaggc
     8761 agagccagac ggcataggtg ccttggcttt gcagtttgaa caattaaaga aaaaattaac
     8821 ggcagaaggt tattttgagc aaaaacacaa gcagcccttg ccacagtttg tatcaaaaat
     8881 tggggtcatt acaagtccta gtggtgctgt tattcgagat attatcacaa ctgtttcacg
     8941 gcgttttcca ggggttgaga ttttattatt cccaactaaa gtacaaggtg atggagccgc
     9001 ccaagaagta gtggcgaata ttcgaagagc caaccaaaga gaggatttgg acttgctcat
     9061 tgttggccgt ggaggtggct cgatagaaga cctttgggct ttcaacgagg aaatagtagt
     9121 tcaggctatc tttgaatcga aacttccagt gatttcgagt gtgggtcatg aaactgatac
     9181 aaccctggca gattttgtgg cagatcgcag agcagccaca ccaacagcag cagcagagtt
     9241 agcaacgcct attacaaaaa cagatcttat gtcttggata gtagagcggc aaaatcgttc
     9301 ctatcaggcc tgcttaagac ggattaagca acggcaagag tgggtggcta aactatcaca
     9361 atctgttatt tttaggcaac cagaacgatt atatgatgcc tacttgcaaa aaattgatcg
     9421 ccttagcatg accctgatga atacgatgaa agatcgtctg agctccgcca aagaaaacaa
     9481 ggttcagttg gatcatgcct tggccaatag tcaattacag acaaaaattg agcggtacca
     9541 agatcgtgtt gctaccgcta agcgtttact gatggctaat atgacaaatc agtacgatag
     9601 ccagctggcc cgatttgaaa aagcccaaga tgctttgcta tcactggatg ccagccgaat
     9661 tatcgcccgt ggttatgcaa tgattgaaaa aaatcaagca ctggtagcct ctgtaagtca
     9721 gataacaaag ggtgatcagt taaccattaa gatgcgtgat ggacaattag atgtagaggt
     9781 agaagatgtc aaaaacgaaa acatttgaag aaaatttaca agatttagag actattgtga
     9841 acaaacttga aaatggggat gtgcccttag aagaagccat ttcagaattt caaaaaggaa
     9901 tgcttctctc aaaagaactt caaaagacct tacaagcggc agaaaaaaca ctcgtcaaag
     9961 tgatgcaagc tgatggcaca gaagtagata tggatgatta atggacaaat tagcaagaat
    10021 tgacgaagcc attcgtcgct actataagac gactagtaac ggtgtatctg aagagttgat
    10081 tgatgccatc ttgtattctg ttgacagtgg tggcaagcgc attcgcccac ttatcttatt
    10141 agagatgatt gagggatttg gggtatcgtt acagaatgct cattttgatt tggctgcagc
    10201 tcttgaaatg attcatacag gaagtctgat tcacgatgat ttgccagcca tggataatga
    10261 tgattaccga cgtggcagac tgaccaatca caaacaattt ggagaagcca cggccatttt
    10321 ggcgggagac agcttatttt tagacccctt tgggttaata gctcaagctg aattaaatag
    10381 tgaggttaaa gtagccttaa tccaagaact ttccctagct tcaggaactt ttggcatggt
    10441 tggtggtcag atgttagata tgaaagggga aaatcaagca ttaagtcttc ctcagttgtc
    10501 actgattcac ctcaataaaa ccggaaaatt attagctttt ccttttaaag cagcagctct
    10561 tataacagaa caggctatga ctgttcgtca acaactagag caggcgggaa tgctcatcgg
    10621 gcacgccttt cagattaggg atgatatttt agacgtgaca gctagctttg aagatcttgg
    10681 aaaaacgcct aaaaaggact tattcgcaga aaaagctact tatccaagtt tactggggtt
    10741 agaagcctct taccaactgc tgacagagag tttagatcag gctttgacga tttttcagac
    10801 actagaaagc gatgtaggct ttaagcctca aataattaca aaactgatag aagggttacg
    10861 acttaatgcc taaagaaaga gtagatgtgt tagcctataa gcaaggatta tttgagacca
    10921 gagagcaagc taagcgtggt gtcatggcag gcttagtggt ctctgtgatt aatggccaac
    10981 gctatgacaa gccaggtgac aaaattgacg atgggactga gttaaaactt aaaggtgaaa
    11041 aactcaaata cgtcagtcgt ggtggattaa aactggaaaa ggggctgcat gtttttggtg
    11101 tatcggttgc taatcaaatt gggattgata ttggcgcttc aacaggtggt tttaccgatg
    11161 ttatgttaca agatggggcc aaactagtct atgccgtcga cgttgggact aaccagttgg
    11221 tatggaaact cagacaagat ccacgagtga gaagtatgga acagtataac tttcgttatg
    11281 ctcagccaga ggactttaat gagggacagc ctgtatttgc cagtattgat gtgtccttta
    11341 tttctctcag cttgattttg ccagccctgc ataacgtttt gtcagatcag ggacaggtta
    11401 ttgctctcat taaaccgcaa tttgaagctg ggcgcgagca gattggtaaa aaaggcatcg
    11461 tcaaagacaa acagattcat gaaaaagtga ttcaaaaggt catggatttt gcctcaggtt
    11521 acggatttac agttaaggga cttgattttt cccctattca gggtggtcat ggcaatatcg
    11581 aatttttagc tcatcttgct aagtcacaga cacctgaaac gttagccccg catttgattc
    11641 agaaagttgt tgccaaggca cataaggagt ttgagaaaca tgaaaaagag tgaacgactt
    11701 gaattaatca aaaaaatggt tttgacgcat ccaattgaga cgcaacatga cctcttaaga
    11761 ttattggcag agcatgggtt agaattaacc caggctacta tttcaagaga catgaatgaa
    11821 attggtatag taaagattcc ttctggcagt ggacgttaca tctatggtct ttctcaagat
    11881 agtggaaaaa agatcgttca aggacctaga tcgataaaga gcactatttt agctgtatct
    11941 gacaaaacaa aaggtttaga acaacacctc tatttaaaag tcgtacctgg caatagtaaa
    12001 ttaatcaaac gttatttatt agcagatttt tcaaaagcta tttttagtct tattgctgat
    12061 gatgatagtt tattgttaat tgcaaagtct ccttcagaag cagatatgat acgccaagaa
    12121 attttgcttt ggatgcaggg tataacctag aaaaaaatag gggagaaagt gatgttatta
    12181 gaaatttcta ttaaaaattt tgctattatt gatgaaattt ccctaaattt tgaaaatggt
    12241 atgacggttt tgacgggtga aactggagca ggaaagtcta ttatcattga tgctatgaat
    12301 atgatgcttg gtgcgcgtgc tagtacagaa gtgattcgtc gtggagctaa taaagcagaa
    12361 attgaggggt tcttttcggt agatgctacc ccagaactgg ttgcgtgtct ggaatcatca
    12421 ggtattgcta tggaagaaga actgattatt cgccgagata tctttgccaa tggcagaagc
    12481 gtgagccgca ttaatggtca gatggttaac ctagccacct taaaacaggt cggacagttt
    12541 ttggtagata ttcatgggca acatgaccaa gaagaattaa tgcgaccaca gctccaccag
    12601 caaattttgg acgcttttgg tgataaggct tttgagcaat tgaaagagaa ctatcagctt
    12661 atttttgatc gttataaaag cttgcgtcgc caggttattg acaaacaaaa aaatgaaaag
    12721 gaacacaaag atcgtattga tatgttggcc tttcagatag cagaaattga agctgctgcc
    12781 ttgagtcgag gtgaggacga ccggttaaat caggaacgtg atcgcttaat gaaccacaaa
    12841 caaattgctg ataccctgac caatgcctac gtcatgctag ataatgacga tttttcaagt
    12901 ctatccaata ttcgctctag catgaatgac ttactatcaa ttgagcagtt tgattcagag
    12961 tacaaaggga tgtcgacttc gatttctgaa gcctattata ttcttgaaga agtgagcaag
    13021 caattatcag ataccattga ccaactggat tttgatggtg ggcgattaca ggaaattgaa
    13081 tttcgcttgg atacactcaa tagcttaacc cgtaaatacg gtggtaatgt gaatgatgtg
    13141 cttgactact acgataatat tatcaaagaa taccagctat taacaggaga tgatttgtct
    13201 tcaggggacc tagaatcaga attgaaagcc ttagaaaaac aattggttgc tgcagccact
    13261 aacttgagtg aacgccgcca tcaattggcg gagcaattag aagctgagat taaagctgaa
    13321 cttaaggaac tttatatgga aaaagcagat ttcaaagttc actttaccac atcaaaattc
    13381 aatcgtgatg gtaatgaaag cttggaattt tacatctcta ctaatccagg cgaaggattc
    13441 aagccccttg tcaaggtggc ttctggagga gagttatcac gccttatgtt agccatcaag
    13501 gctgctattt ctagaaaaga agataagacg agtattgttt ttgatgaagt agatacaggt
    13561 gtttctggtc gcgttgcgca agccattgcc caaaaaattt ataaaattgg gcgacatggg
    13621 caagttctcg ctatttcaca cttacctcaa gttattgcta ttgctgatta tcagtatttt
    13681 atttctaaag aaagtaaaga agagtccacc gtttctaagg taaggttatt aactcctgaa
    13741 gaacgtgtgg aagaaattgc tagcatgatt gcaggaacag atatgacaca agctgctctt
    13801 acgcaggctc gtgaactact tgccaaacat taagattatg tttggtattt gatattttca
    13861 taattagatg aaattgattt tttaggtgct aaaataatca ttgtgctaga ccatttttcc
    13921 tctgttaatc tggcttggtt tgccttgaca aacctctgag aaatagtaga atagataaga
    13981 gaattttaag ctgaggggat agaaatgact agtaaaaaag cgtgtttatc aagtatcatt
    14041 gtgttagcaa gtttaacgtg tggaaatgat actgttagtg ccaatcatct ctcagcaact
    14101 ggagataagt ttgatgattg ctcaacactt gttgaaaaag atgtggcccc taaagatgaa
    14161 cttgagatgt tagcatggtc ctcgtctcaa acaactgatg atgctgacag agactatgaa
    14221 gattttctcg atgatgattc ttttatttct caaaatgaaa ctgataagat gtttgagaat
    14281 ttaactgatg ataggttatt aaatgaatta gatgaattag atgaagaaaa tgaagaagat
    14341 gaagaagatg aagaagatac aattgagcca gagcaaaatg taataatgcc tagtgacgat
    14401 gagctatttg atttaactga tgctgttgag acacgcctta ctgtttctag tgctccccat
    14461 ttagaggctg aattgccgaa accacatttg aggagcctat cagatacagc actgcggtct
    14521 ggtgaaatta gaggacattt agataacaaa ctggacgctt tgtctgtaac agctacaaag
    14581 ttagcattaa cgatggctca aaaatttgat ttgacaacgc atgtctattc tataggtgaa
    14641 agctttagtg aagtattagc tgctcattat gaagacagaa aagcagaatc agctttttct
    14701 aagaaaaaga gatttcacct tcctattgct actccagatg ttgttataga ggagttaagg
    14761 cgcctagtct cttctattgg aagttcaaaa gaagatgttt cagttcctta tagtcggaag
    14821 ctaggtatgg cagttgcaaa aagaaaaata gccctgccac aaacgggaga ggggttctct
    14881 tattatccag ttttacttgg tttaatgata ttaggattaa cgccgattat gataccaaag
    14941 aagataaata attaggtaat aagttattgt agttgtaaaa gacggggcaa atgttcaagc
    15001 gtgaaaaggt tgacttttgc ctcgttttgt atctcgttat tgctaaggca ttttcttcga
    15061 gcagctagtg ctcgccatac ctatctaccg agtgattatt caatagcact accagttttg
    15121 ctttatttag taaggagtgt tagaataaag aggtgagaaa ctagtttaga atggaaaaat
    15181 acatgggaac tataaaaatt gttacagatt catcaataac tattgaacca gaattaatta
    15241 aagctttaga tattactgta gtacctttat ctgtcatgat tgatagcaaa ttatattctg
    15301 ataatgattt aaaagaagaa ggtcattttt tgagccttat gaaggctagc aaatcccttc
    15361 ccaaaaccag tcagccaccg gttggtctct ttgctgaaac ttacgaaaat ttggtcaaaa
    15421 aaggagtaac tgacattgtt gctattcacc tctcaccagc tttatcaggt actattgaag
    15481 cttcccgtca gggggctgaa atcgctgagg cacctgttac agttttagat tcaggattta
    15541 ctgatcaagc catgaaattt caggtcgttg aggcagcaaa gatggcaaaa gcgggtgcta
    15601 gtttgaatga gattttggct gctgttcaag ctatcaaatc aaaaacagag ctctacattg
    15661 gtgtatctac cttagaaaat ttagtaaaag gaggtcgtat tggtcgtgtg acgggtgttt
    15721 tgagctcgct acttaatgtc aaagttgtta tggcacttaa aaatgatgag ttaaaaacgc
    15781 ttgtcaaagg tcgaggtaat aaaacattta cgaaatggtt agatagttac ctcgctaaaa
    15841 atagtcatcg cccgattgca gagatagcta tttcttatgc tggtgaagct agcctggcat
    15901 taaccttaaa agaaagaatc gcagcttatt acaaccactc tatttcggtt ttagaaacag
    15961 gctctatcat ccaaacacat acaggagaag gagcttttgc ggttatggtt cgttatgaat
    16021 aatcgtcatt tatttagtgg gatatttttc tttgttatta gtttatgtct ggccttttta
    16081 ttgctaaata ttattatccc taagtcaaat tcacgtttga aaaagagtga ttttctgaaa
    16141 aaagaacaag tagctatcca atatgttgct ataggagatt cattgacaga aggagtaggt
    16201 gatctaactc atcaaggtgg ttttgttcct ttgttaacga atgatctcag tgaatatttt
    16261 aaggctaatg ttaatcatca aaattacggc gtatctggtg ataccagtca acaaattctt
    16321 gataggatga taaaacaaaa gcaggtacag ttatctttaa aaaaagcaga tataatgacg
    16381 ttaaccgttg gtggtaatga tgttatggca gttattcgga agaatttagc ggatttgcaa
    16441 gtttctagtt ttagaaagcc agctcgtcag tatcaaaaac gattaagaca gattatcgag
    16501 ttagccagaa aagataataa agatcttcct atttttatct taggcatcta taatccgttt
    16561 tatttgaatt ttccagaact aactgatatg caaaaagtga ttgatgactg gaataccaaa
    16621 actaaggagg ttgttggaga atacgatcgt gtgtactttg tgccaataaa tgacctcttg
    16681 tataaaggga taaatggaca agaaggaatt gtccattctt caggagatca aactacaatt
    16741 gtcaatgatg ccttgtttac tggggaccat tttcacccaa ataatactgg ctatcaaatc
    16801 atgtcaaatg cagtaatgga gaaaataaaa aagcatgaaa aaaaaatcaa accttaattg
    16861 gtggaagtgg agcttcttat gtctgcttgc ttttaatacc gcctttttga tggttattgc
    16921 aagtcgtctc attcaagtaa gagaacctga gtcagaactg attgctaaaa aaccagttaa
    16981 aaatatcaaa attggtacat ttgtcacaac cagagaacag cttaacgaaa ctgtagcaag
    17041 ttatcttaaa gattatcaga ctaaaaagat gtcttataaa ttttatgcga catcttcttc
    17101 tattttgttt gaaggaactt atcaattatt agggtatgaa gtccctttat atatctattt
    17161 tcaacctcat cgtctagaaa atggagctgt ccaactacag gtgatctctt tttcagtggg
    17221 aactctgcca ctcccagaaa aagatgtttt gcagtatttg aaatcaagct acaaattgcc
    17281 aagctttgtt aaagtgatgc caaatcaatc agctatcgtt gttaatttac aagatatcca
    17341 aaatgatgct aaggtttatt taaaagccaa gaaaattgat ttatttaatg atgaaatcag
    17401 ttttaacatc tataagaaat aagctcaaat aacgttaaat acttgaccta atcgcttttt
    17461 ttagatatga taatatctgt taaagcatta agcttactaa ttatttggag gatttgttaa
    17521 atggctaaca aacaagattt aatcgcaaag gttgcagaag caactgaatt gactaaaaaa
    17581 gattcagcag cagcagttga tgccgtgttt tctacaatcg aagctttcct tgctgaaggt
    17641 gaaaaagtac aattgatcgg ttttggtaac ttcgaagtac gcgaacgtgc agctcgtaaa
    17701 ggtcgtaacc cacaaactgg tgcagaaatt gaaattgcag cttcaaaagt tccagccttc
    17761 aaagctggta aagctcttaa agacgctgtt aaataattgc atatataaaa gcccattgta
    17821 caagcgttgt agcctgtgca gtgggctttt ttgtgttcag gggggtaaaa aaggggtaaa
    17881 aaatttaata gttttccata atatcagcta cacttgattt cattttcttt gtgacatgag
    17941 tataaatttg ggcagtagtt ttagcgtctg catgtcctac acgttccatg attgatttta
    18001 gcggcacgtt attctctgct agacggctaa taagagtgtg acggaagatg tggctagtaa
    18061 gtttttttgt aattgggtct tccaatcttt cattagcttt ttttaaagct aagttgaatg
    18121 agttagtctg aattggaaca ccgttttttg ttgtaaaaag gtatcccata tctctatatc
    18181 tatgatttgt atttttttct agttcgttca taaattctaa ctcttgtaga atttcaagtt
    18241 ctctacttgt catgatggtt tcacgataag aagctaatgt ctttggtgct gtcttttccc
    18301 cgttacgata tccttctgta tgatcaaatg ttccgtgcaa ctgcaatatt cttgacttag
    18361 attcgtagtt gcacggctca atgctgacag cttcaccgat acgacaaccg ttcaaactga
    18421 taaactcagc caacaaacca agacggtaag tgctaggtct tctgtacaat tctttcaata
    18481 atggtttaat ttcatcttct tcaagatatt tttcttcagc ctttttccag tcttcaaggg
    18541 ttttctttac ccttgggagt ttagcacgtc ttgcaggatt atcttggata atatccaaac
    18601 caacagcata atcaaatgct aagtttagca tagacttatt acgctctttt ttattcctag
    18661 agcaatctag gttatcgaga taattctgaa cgtatttagg atcaatattc actactttaa
    18721 cacctattcc aaaagtttcc cttatctctt cgatattacc tctcagagaa gctacagacg
    18781 accttttaag ttctttctta taaaacgccc accattcatc taaaagttcc gtgaaaagta
    18841 actcagaggc ctttaattgc gctatttttt ctgttatttt ttgttcaagg atttttcgag
    18901 ctgctttata agctcttgaa ttatccttct ccatagtaac ggatacaggt ttccatgttc
    18961 cagtgtaagg atctttataa ttttcacgaa atttgaattt accgttatca gtttcttcta
    19021 tccacatttg ttttttacct cattttctgt taaaataggt atagtaaaga gacctactgc
    19081 gaagcaggtt tttactatac tagattcgcc tcacgctctc ctcgccaaat ttgagcgtgg
    19141 ggcttttttg ttagttgaga aaccaagatg ctatcgactc taataatcca gcatttttac
    19201 tttttgatac tctatctact tttaaaatag tcaatcgtaa cttataagtt atatctttct
    19261 ttttagtaac cacggtcttt aaatcgtttt tgagtgtttt gtattgtcca ccacgaccag
    19321 taagcgttgc ttccatttgg taatgactag atttttttac ataaggggtt aatcgtttag
    19381 ctaagtctgc tggaaagtag ccaacaaaag ttttgtttac catgactttt atggcatttg
    19441 gatcgtgacg attaagaggt tctctgacaa tctctacatc ttttgttgag accctgtaat
    19501 acttgtagat atccttgaag tttgatttta tgtagtcaga aataaaatct ttatccttat
    19561 cccagtatgg tgatttctta ccaatttcag ccataacttt attagcttct ttttcatgat
    19621 aatttgttcc cattaagaga aagttatctt ggaatatgac ttttgccata acagtctcct
    19681 ttaatattcc ctataaatat ccacaacttc accgattgtg cggatgtcgt catcctttga
    19741 tagatagatt tcctcatagc ttttatttaa actttgcaag taccaagcgc catcataatc
    19801 acgcttgagt ttttttacaa agtttttacc attgacttgg aatatcccta tatcattcat
    19861 atcgacttgg ctagatacct tgatgaatag caaatcgttg tcttgaataa gtggttccat
    19921 tgaatcgcca gctacttttg caatagtatc atactcatcg gggacatcat cagaacgtag
    19981 tttaactttc atgtgtaaat tgtcttcttg gtatgcccca agaccagcgg caaccaatcc
    20041 ctcaacgtag tcagtgatat aatcttctgt ctcctcagat tttttatcga atatagaaac
    20101 ggttttattt tgttcttcta attgttcgtt agcgaagttg aggacttttt cttgtctagg
    20161 ttgttctagt tggttgtata tagaaacgat ttcaggttgt tcgttctgta ttgtgatttt
    20221 cccaagttta ctatctgtga gtcctaaaag atagtcagag gtaacgttga aaatctctgc
    20281 tagttttttt aggtctttac cttttggaaa attttcattc ttctcccact ttgaaacagt
    20341 agtataggtt ttcatgccca atatttctga aagttcagtc tgagtcatgt tgcgcccttc
    20401 tctcaacttt cttattcggt cccctaattg ctccatagga tacctccttt ttaattttga
    20461 taagtaaatt atatcaaaac catgattata aatcaactat ataagaaaaa agttttaaat
    20521 aaactatatg atttacgatt ttttcaaaaa aacagaaaat aaatcatata aaacacttga
    20581 cgcaagattt aaaatcatat agaatgtaat catcatcaag aaaggagcga ctcagctatg
    20641 gtaactattg cagaattaag agctaaacat aataagatgt cacagcgtga attggcaaaa
    20701 gaattaggtg ttactcaaac atctatcagc aactgggaaa aagaccagac aaagatttca
    20761 ggtgagtatc ttattagtct agctttgttt ttcgatgtat ctaccgatga cattcttggg
    20821 ataaacaagc aagcaacaca aaaattttaa acactatatg atttaaaatc ata
//
