LOCUS       NZ_CP035413            20747 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain SRCM103629 chromosome, complete genome.
ACCESSION   NZ_CP035413
VERSION     NZ_CP035413.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4129860)
  AUTHORS   Kim,tw., Jeong,S.Y. and Jeong,D.Y.
  TITLE     Genome sequence of Bacillus subtilis SRCM103629
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4129860)
  AUTHORS   Kim,tw., Jeong,S.Y. and Jeong,D.Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2019) Research Institute, Chunlab, 6F, JW TOWER,
            2477, Nambusunhwan-ro, Seocho-gu, Seoul 06725, Korea, Democratic
            People's Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: HGAP v. 2.3.0; pilon v. 1.22
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 167.11x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004119815.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:34:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,288
            CDSs (total)                      :: 4,167
            Genes (coding)                    :: 4,074
            CDSs (with protein)               :: 4,074
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 93
            CDSs (without protein)            :: 93
            Pseudo Genes (ambiguous residues) :: 0 of 93
            Pseudo Genes (frameshifted)       :: 54 of 93
            Pseudo Genes (incomplete)         :: 47 of 93
            Pseudo Genes (internal stop)      :: 13 of 93
            Pseudo Genes (multiple problems)  :: 21 of 93
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:21:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3481744
            Orig. end                         :: 3502491
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP035413.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Microbial Institute for
            Fermentation Industry, 61-27 Minsongmaeul-gil, Sunchang-eup,
            Sunchang-gun, Jeollabuk-do, Republic of Korea.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20747
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="CDPS"
                     /region_number="10"
                     /rules="CDPS"
                     /tool="antismash"
     cand_cluster    1..20747
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20747
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10747](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10747)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     gene            complement(436..1368)
                     /gene="hprK"
                     /locus_tag="ETL58_RS18235"
                     /old_locus_tag="ETL58_18235"
     CDS             complement(436..1368)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hprK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391380.1"
                     /locus_tag="ETL58_RS18235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18235"
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="WP_003228097.1"
                     /transl_table=11
                     /translation="MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYFT
                     YYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEK
                     NGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETA
                     LELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRS
                     NKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMN
                     FRLKRMGLNAAEQFTNKLADVIEDGEQEE"
     misc_feature    1480..1495
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.26"
                     /tool="antismash"
     gene            1550..2740
                     /gene="nagA"
                     /locus_tag="ETL58_RS18240"
                     /old_locus_tag="ETL58_18240"
     CDS             1550..2740
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391381.1"
                     /locus_tag="ETL58_RS18240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18240"
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="WP_014481023.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.3e-42, bitscore:
                     142.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAESLLIKDIAIVTENEVIKNGYVGINDGKISTVSTERPKESYSK
                     EIQAPADSVLLPGMIDIHIHGGYGADTMDASFSTLDIMSSRLPEEGTTSFLATTITQEH
                     GNISQALVNAREWKAAEESSLLGAELLGIHLEGPFVSPKRAGAQPKEWIRPSDVALFKK
                     WQQEAGGLIKIVTLAPEEDQHFELIRHLKDESIIASMGHTDADSALLSDAAKAGASHMT
                     HLYNAMSPFHHREPGVIGTALAHDGFVTELIADGIHSHPLAAKLAFLAKGSSKLILITD
                     SMRAKGLKDGVYEFGGQSVTVRGRTALLSDGTLAGSILKMNEGARHMREFTNCSWTDIA
                     NITSANAAKQLGIFDRKGSVTVGKDADLVIVSSDCEVILTICRGNIAFISKEADQI"
     gene            2737..3465
                     /gene="nagB"
                     /locus_tag="ETL58_RS18245"
                     /old_locus_tag="ETL58_18245"
     CDS             2737..3465
                     /EC_number="3.5.99.6"
                     /GO_function="GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="nagB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391382.1"
                     /locus_tag="ETL58_RS18245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18245"
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="WP_129010251.1"
                     /transl_table=11
                     /translation="MKVMECQTYEELSQKAARITADTIKEKPDAVLGLATGGTPEGTYR
                     ELIRLHQTENLSFQNVTTVNLDEYARLSSNAPNSYHFYMNDRLFQHIDSKPSRHFIPNG
                     NADDLEDECRRYEQLVESLGGTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQTRQ
                     ANARYFPSIDSVPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASA
                     LHLHSDVTVLIDREAASLRP"
     gene            3483..4214
                     /gene="nagR"
                     /gene_synonym="yvoA"
                     /locus_tag="ETL58_RS18250"
                     /old_locus_tag="ETL58_18250"
     CDS             3483..4214
                     /codon_start=1
                     /gene="nagR"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="yvoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391383.1"
                     /locus_tag="ETL58_RS18250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18250"
                     /product="N-acetylglucosamine utilization transcriptional
                     regulator NagR"
                     /protein_id="WP_014478108.1"
                     /transl_table=11
                     /translation="MNINKQSPIPIYYQIMEQLKTQIKSGELQPDMPLPSEREYAEQFG
                     ISRMTVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMTPGSRL
                     IDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHIPFELAGELNESHFQ
                     SSIYDHIERYNSIPISRAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNGTAFE
                     HAKSVYRGDRYTFVHYMDRLS"
     gene            complement(4234..8103)
                     /gene="yvnB"
                     /locus_tag="ETL58_RS18255"
                     /old_locus_tag="ETL58_18255"
     CDS             complement(4234..8103)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yvnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391384.1"
                     /locus_tag="ETL58_RS18255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18255"
                     /product="metallophosphoesterase"
                     /protein_id="WP_101172221.1"
                     /transl_table=11
                     /translation="MRKYTVIASILLSFLSVLSGGHHESKAVPVVQQELFQTPHYIPLL
                     ENPPQIDVKAEMRSNLMIEAQVRDNSYQAFSAFLFYKQSNELGYKMVPMDPTPGAVRKF
                     LAQIPKRLIWNSELEYYIVMSNGKQRVESETKKLKLEGYQADLAHIPELLITELAVDTK
                     NIGRADGYEFIEIYNTTDRTIDFKDYHIRYRYPKEGPDSDLIWRPDERILIPSGETFVV
                     WLKPAGHPELTSEDFNRYYQTQLKEGKNLAVIDETEGMANTRPRAVVISTNTGKDISVA
                     HYRKHALRRLSSVLYKYPLNGTAELLNISIGEKNPSPGTVLQAQVPEQKRKIKLDKEKP
                     VIEDLTDRKPVRPAESIELRADIRDRSLVKTAAFYYRTDENKPFKRILAEKDRNDNLYH
                     YIVYSPELIGKDQLEYYVAAGDGINEARTPVKMIDIKQTSKSHGLRMNIENRDTLSGTQ
                     FLKATTEGRADRIKLWIDGKKQVTEPAMEKEVYFAFDTRKTNLYFKNAVTMEGKVLKVF
                     DDTTNKYRTYSVPLPETLLRKGKQLQRITIRSGSKVSPFDTAENRDDFLVKNARLVLSD
                     GTVIRDQRVSPEKELFIGDNQRSNKSWQFQFNLPDGLFTSQLLEWDTSKLSEGAHHIQA
                     SDGKENVSLVVRVDNSGPHIEPNITEGQTYKGNLILQADMYDKWSKIEEAEASLDGESI
                     TLPYHTSSSDLLPGKHSLKVTATDLAGNKTVIERIFKTEREHPDQPEVIDSEADTHKAK
                     LSVRVKDPTNDAMDVGFYRGFQYTARNHVKIFKHASLTEPPKSFVPERETPFTNKELER
                     VSAADGKTVSTENKELFPYHRFEVTVDPSIDENDLAEAVWKGSSLPGRKVTMYAWNYRT
                     NEWQPVDSFVAKDDKSFTLKASVIAADFVRESKMNVIVQDEIPPAKDMYTFVWMSDTQY
                     YAESYPHIFDKQTEWIKDNQKQLNIKYVFHTGDIVDDSADIRQWKNADRSMSVLDKSGI
                     PYGVLAGNHDVGHKDGSYRAFGKYFGSDRFDKKLHYGGSYKNNRGHYDLISSNGNDYIM
                     LYMGWGITDEDIAWMNQVLKKHPDRIAILAFHEYLLVSGNRSPIGEKIFKEIVKPNPNV
                     VMVLSGHYHSAMRKTDELDDDGDGKPDRLVHQMLADYQGGPEGGQGYLRLLQFDQANDM
                     VHVSTYSPYVKDKNYYDTDIYGNKDEFSLSLDLKPRIKKVETDYFECNVYTNEELGKRE
                     QVKSGDTAEFRWDHLEPQSVYYWYIIVEDSFNGKTKSPIWKFKTKKETYRPAPDQFDFR
                     HVSNP"
     gene            8268..8729
                     /gene="pchA"
                     /locus_tag="ETL58_RS18260"
                     /old_locus_tag="ETL58_18260"
     CDS             8268..8729
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="pchA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391385.1"
                     /locus_tag="ETL58_RS18260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18260"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_029318333.1"
                     /transl_table=11
                     /translation="MNNSIHDELFQAIQQFALKRDKRVWQKVQIPSSQHLDHLKKDWTL
                     TQLHIVSCLHTSKNVNNSFLASRLHISKAAVSKAIQALLKHNIITVTKKPGNKKEIFYT
                     LTESGKELAGLHEQLHQKAKEQYKQLFNEFSIDELKTVTAFINLWIKHM"
     gene            complement(8768..9985)
                     /gene="cypX"
                     /locus_tag="ETL58_RS18265"
                     /old_locus_tag="ETL58_18265"
     CDS             complement(8768..9985)
                     /EC_number="1.14.15.13"
                     /codon_start=1
                     /gene="cypX"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391386.1"
                     /locus_tag="ETL58_RS18265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18265"
                     /product="pulcherriminic acid synthase"
                     /protein_id="WP_101172222.1"
                     /sec_met_domain="p450 (E-value: 5.1e-36, bitscore: 122.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSIKLFSVLSDQFQNNPYAYFSQLREEDPVHYEESIDSYFISR
                     YHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKEHSAKRRIVVRSFIGDALDHL
                     SPLIKQNAENLLAPYLERGKIDLVNDFGKTFAVCVTMDMLGLDKRDHEKISEWHSGVAD
                     FITSISQSPEARAHSLWCSEQLSQYLMPVIKERRVNPGSDLISILCTSEYEGMALSDKD
                     ILALILNVLLAATEPADKTLALMIYHLLNNPEQMNDVLADRSLVPRAIAETLRYKPPVQ
                     LIPRQLSQDTVVGGMEIKKDTIVFCMIGAANRDPEAFEQPDVFNIHREDLGIKSAFSGA
                     ARHLAFGSGIHNCVGAAFAKTEIEIVANIVLDKMRNIRLEEDFCYAESGLYTRGPVSLH
                     IVFDRA"
     gene            complement(10001..10747)
                     /gene="pchC"
                     /locus_tag="ETL58_RS18270"
                     /old_locus_tag="ETL58_18270"
     CDS             complement(10001..10747)
                     /EC_number="2.3.2.22"
                     /codon_start=1
                     /gene="pchC"
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391387.1"
                     /locus_tag="ETL58_RS18270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18270"
                     /product="cyclo(L-leucyl-L-leucyl) synthase"
                     /protein_id="WP_101172223.1"
                     /sec_met_domain="CDPS (E-value: 1.9e-82, bitscore: 274.2,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGMVTERRSVHFIAEALTENCREIFERRRHVLVGISPFNSRFSE
                     DYIYRLIGWAKAQFKSVSVLLAGHEAANLLEALGTPRGKAERKVRKEVSRNRRFAERAL
                     VAHGGDPKAIHTFSDFMDNKAYQLLRQEVEHAFFDQPHFRHACLDMSREAIIGRARGVS
                     LMMEEVSEDMLNLAVEYVIAELPFFIGAPDILEVEETLLAYHRPWKLGEKISNHEFSIC
                     MRPNQGYLIVQEMAQMLSEKRITCEG"
     misc_feature    10873..10888
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    10875..10889
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.98"
                     /tool="antismash"
     misc_feature    complement(10876..10891)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.77"
                     /tool="antismash"
     gene            11173..11682
                     /gene="pchR"
                     /locus_tag="ETL58_RS18275"
                     /old_locus_tag="ETL58_18275"
     CDS             11173..11682
                     /codon_start=1
                     /gene="pchR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391388.1"
                     /locus_tag="ETL58_RS18275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18275"
                     /product="pulcherriminic acid biosynthesis transcriptional
                     regulator PchR"
                     /protein_id="WP_003228073.1"
                     /transl_table=11
                     /translation="MSDLTKQMIYDIYVRLLHLNEQKANTSLQQFFKEAAEEDVAEIPK
                     NMTSIHVIDCIGQHEPINNAGIARKMNLSKANVTKISTKLIKEEFINSYQLTDNKKEVY
                     FKLTRKGRRIFDLHEKLHKKKELAFYQFLDSFSQEEQKAVLKFLEQLTSTLEAEQTDGT
                     PDKPVK"
     gene            11703..12914
                     /gene="pchE"
                     /locus_tag="ETL58_RS18280"
                     /old_locus_tag="ETL58_18280"
     CDS             11703..12914
                     /codon_start=1
                     /gene="pchE"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391389.1"
                     /locus_tag="ETL58_RS18280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18280"
                     /product="MFS transporter"
                     /protein_id="WP_101172224.1"
                     /transl_table=11
                     /translation="MAHTKSKAVLILYTVCFSAFFASLSQNIYSPILPIIKESFHVSTA
                     MVNLSVSVFMIVTAIMQIILGAIIDFKGARIVLITGILATAAASIGCAVTTDFTLFLIF
                     RMIQAAGSAALPLIAATTIGQLFTGNERGSAMGTYQMLLSVAPAIAPVLGGFIGGAAGY
                     EGIFWILAAISIVLLVTNSIIFPKDSPTESMQQAKGNVFAHYKSIFTNRTGNVILTLSF
                     VLFFIYFAVIVYLPILLTEHYHIDVGIAGLLYLPLALSTIAGTFLFKRIQAKIGLHTLF
                     IGSNVIAACSIILFAVTHSVSLVLMALTLALFGISMGVIPPLYSTMITNEFEHNRGSAI
                     GMFNFIRYTGMAAGPMVSAYLLTMMPSAISFSLLGLGFAALSFCLLPPMFSPQKRTKQK
                     KHHM"
     gene            complement(12943..13302)
                     /gene="yvlD"
                     /locus_tag="ETL58_RS18285"
                     /old_locus_tag="ETL58_18285"
     CDS             complement(12943..13302)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene="yvlD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391390.1"
                     /locus_tag="ETL58_RS18285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18285"
                     /product="phage holin family protein"
                     /protein_id="WP_003228066.1"
                     /transl_table=11
                     /translation="MVKWAVSILVNALLLIVIDGYIDSIHISSIGAAIIASLILSILNV
                     LIKPLLIIFTLPVTMVTLGLFLFVINAITLMMTASIMGDSFQIDGFGTAIWASVILSVF
                     HLLIQKGILEPLRKK"
     gene            complement(13304..13501)
                     /gene="yvlC"
                     /locus_tag="ETL58_RS18290"
                     /old_locus_tag="ETL58_18290"
     CDS             complement(13304..13501)
                     /codon_start=1
                     /gene="yvlC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391391.1"
                     /locus_tag="ETL58_RS18290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18290"
                     /product="PspC domain-containing protein"
                     /protein_id="WP_003228065.1"
                     /transl_table=11
                     /translation="MNKLYRSEKNKKIAGVIGGLAEYFNWDASLLRVITVILAIMTSVL
                     PVLLIYIIWIFIVPSERDMK"
     gene            complement(13506..14603)
                     /gene="yvlB"
                     /locus_tag="ETL58_RS18295"
                     /old_locus_tag="ETL58_18295"
     CDS             complement(13506..14603)
                     /codon_start=1
                     /gene="yvlB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391392.1"
                     /locus_tag="ETL58_RS18295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18295"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_003228061.1"
                     /transl_table=11
                     /translation="MKQEKERILKLVEEGKLTAQEALTLIEKLDSDYKEKEEKITALSV
                     HVHDEEEPFTTAKKESGKPSLGAKLFDWIDSAVKKVKEVDLDLNFGHAYDVQHIFQFKD
                     TDFSSVELQIANGSVNIVPWEDDDIRAECQAKVYRADSQDAARHAFLQHIECEIKGNKF
                     FIRTEKKTMKTNVTLYIPQKEYDKIRVKLFNGPVRGEHLHVKEFSAKTTNGVLSFSYLT
                     AEKAIAETANGQIKLASHSCGTIEAETINGLIDLRGKSESIDVQSFNGNIAINVTESDC
                     RSIYAKTTTGNVELAIPDDLAVKAELKSNLGTLSHELMDVEMLKEKNDTIQKEMMFTSN
                     QAHDQNITVFSESLTGAIKLKYSQR"
     gene            complement(14628..14954)
                     /gene="yvlA"
                     /locus_tag="ETL58_RS18300"
                     /old_locus_tag="ETL58_18300"
     CDS             complement(14628..14954)
                     /codon_start=1
                     /gene="yvlA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391393.1"
                     /locus_tag="ETL58_RS18300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18300"
                     /product="protein YvlA"
                     /protein_id="WP_003244375.1"
                     /transl_table=11
                     /translation="MNRNQAIIASLCYFSVFIAPIIVPIVAYFVVNEKETKRHAIRSLI
                     SHIVPFVGWLFLFIALLGGAVAIDGDSLLPVFVIIGGAVIYFLVVIGIIIWNVIQGIKV
                     LRAA"
     gene            15172..15402
                     /locus_tag="ETL58_RS18305"
                     /old_locus_tag="ETL58_18305"
     CDS             15172..15402
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391394.1"
                     /locus_tag="ETL58_RS18305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18305"
                     /product="hypothetical protein"
                     /protein_id="WP_003235419.1"
                     /transl_table=11
                     /translation="MEKDPSDYTVTQESVLKLIHEQKRMNREMIAELEQIHGPFPISHD
                     IQYIKVLLDSSNTHIVQDLMSVSKQLYKKTL"
     misc_feature    complement(15188..15203)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(15601..16422)
                     /gene="hag"
                     /locus_tag="ETL58_RS18310"
                     /old_locus_tag="ETL58_18310"
     CDS             complement(15601..16422)
                     /codon_start=1
                     /gene="hag"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391416.1"
                     /locus_tag="ETL58_RS18310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18310"
                     /product="flagellin Hag"
                     /protein_id="WP_101172225.1"
                     /transl_table=11
                     /translation="MRINHNIAALNTLNRLSSNNSASSKNMEKLSSGLRINRAGDDAAG
                     LAISEKMRGQIRGLEMASKNSQDGISLIQTAEGALTETHAILQRMRELTVQAGNTGTQQ
                     PEDLTAIKDEMDALTEEIDGISQRTEFNGKKLLDGSETAGFTFQIGANAGQNINVTIGN
                     MDATTLGVKGIDVSADDFSFDTEIVKIDSAITSVSNQRAKLGAVQNRLEHTINNLGASS
                     ENLTAAESRIRDVDMAKEMSDFTKNNILSQASQAMLAQANQQPQNVLQLLR"
     gene            complement(16761..19634)
                     /gene="uvrA"
                     /locus_tag="ETL58_RS18315"
                     /old_locus_tag="ETL58_18315"
     CDS             complement(16761..19634)
                     /EC_number="3.1.25.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uvrA"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391396.1"
                     /locus_tag="ETL58_RS18315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ETL58_18315"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_003228057.1"
                     /transl_table=11
                     /translation="MAMDRIEVKGARAHNLKNIDVTIPRDQLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMDKPDVDAIEGLSPAISIDQKTTSRNPRSTVGTVT
                     EIYDYLRLLYARVGKPHCPEHGIEITSQTIEQMVDRILEYPERTKLQVLAPIVSGRKGA
                     HVKVLEQIRKQGYVRVRIDGEMAELSDDIELEKNKKHSIEVVIDRIVVKEGVAARLSDS
                     LETALRLGEGRVMIDVIGEEELMFSEHHACPHCGFSIGELEPRLFSFNSPFGACPTCDG
                     LGMKLEVDADLVIPNQDLSLKENAVAPWTPISSQYYPQLLEAVCTHYGIDMDVPVKDLP
                     KHQLDKVLYGSGDDLIYFRYENDFGQIREGEIQFEGVLRNIERRYKETGSDFIREQMEQ
                     YMSQKSCPTCKGYRLKKEALAVLIDGRHIGKITELSVADALAFFKDLTLSEKDMQIANL
                     ILREIVERLSFLDKVGLDYLTLSRAAGTLSGGEAQRIRLATQIGSRLSGVLYILDEPSI
                     GLHQRDNDRLISALKNMRDLGNTLIVVEHDEDTMMAADYLIDIGPGAGIHGGQVISAGT
                     PEEVMEDPNSLTGSYLSGKKFIPLPPERRKPDGRYIEIKGASENNLKKVNAKFPLGTFT
                     AVTGVSGSGKSTLVNEILHKALAQKLHKAKAKPGSHKEIKGLDHLDKVIDIDQAPIGRT
                     PRSNPATYTGVFDDIRDVFAQTNEAKVRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHF
                     LPDVYVPCEVCHGKRYNRETLEVTYKGKSISDVLDMTVEDALSFFENIPKIKRKLQTLY
                     DVGLGYITLGQPATTLSGGEAQRVKLASELHKRSTGRTLYILDEPTTGLHVDDIARLLV
                     VLQRLVDNGDTVLVIEHNLDIIKTADYIVDLGPEGGAGGGTIVASGTPEEITEVEESYT
                     GRYLKPVIERDKTRMKSLLKAKETATS"
ORIGIN
        1 aagttccccc agcggccgat cgcctggccg agcaaaatgc tgggcgcggc aatatccgca
       61 agcttccaga acgaaaggtt tttcactctc gaaaacacat aacccgttaa aatggcgccg
      121 attaatccgc catgaatggc aatgccgccc ttccaaatct taatgatttc tcccggatgt
      181 gccgcataat agtcccattc aaaggcaacg taataaattc gtgcgcaaat aatcgcaatt
      241 ggaatggcaa acaggacaag atcaataaac gtatctttct gcagcccccg tttttcactt
      301 tccctcatcg caatccacag cccgagcaaa gcaccgagac cgataatgat tccgtaccaa
      361 tggacggcta acggccccag ctgaaatgct atcggattga gtggttctat cgcttcattc
      421 atttaacgcc aactcctatt cttcttgttc accgtcttca atgacgtccg ccagcttgtt
      481 ggtaaattgt tcagcggcat tcagccccat ccgcttcaat ctgaagttca ttgctgccac
      541 ttcgatgatg actgcaagat ttcggcctgg gcggacggga atcgtcagtt ttgtaatttc
      601 tgtatcaatg attttcatgg tctcttcctc aagtccgagc cggtcgtatt gcttgccctg
      661 ctcccagagt tcaagattca tgacaatcgt gattcgttta ttgcttctga ccgcgccagc
      721 gccaaatagc gtcatcacat tgataatgcc aaggcccctg atctcaagaa ggtgctcaat
      781 taattccgga gcgtttccca caagagtatc ctgatcctcc tgccgtattt caacgcaatc
      841 atcggcaaca aggcgatgcc ctcttttcac aagctccagc gctgtttcgc tttttccgac
      901 gccgctcttt cctgtgatca gcacgccgac accatatata tcgacaagaa cgccatgaat
      961 tgctgtggta ggcgccagcc tgctctcaag gaagttggtt aaacggcttg acagtcttgt
     1021 cgttttcagc ggcgatctga ggacaggcac cccatttttc tcggaggcgt caatcagctc
     1081 ctgcgggatg ggcatatctc tagaaagaat aatagctggt gttacatcag tgcacagaga
     1141 atccattcgc tgttttttct cctcttcagg aagctgttca aagaaagaaa gctctgtttt
     1201 tccgagaagc tgcacgcgct ctctcgggta atatgtaaaa tatccggcaa tttcaatgcc
     1261 tggtcttgat aggtcactca ttgtaatcgg gcggttaatt ccttcttctc cgctgattaa
     1321 ttccaaattg aactgttcca ttacgtcttt tgtgcgaacc tttgccacga tatgttcctc
     1381 ctgttccggg ctgccccgag cttgctcaca atactttcat tttatcactt tcaggcttga
     1441 acctaaaaca gattttataa aaggcgggaa aacacctcag ctggtctaga tcactagtct
     1501 gaaaaagagt aaaataaagg tattcaaatt ccagaaaggc ggatcatcta tggcagagag
     1561 tcttcttatc aaagacattg cgatcgtgac agaaaatgaa gtaatcaaaa acggctatgt
     1621 cggaatcaat gacggaaaaa tcagcacagt ctcaacagaa cggcccaagg agtcatattc
     1681 aaaagagatt caagcacctg cggattccgt tttgcttccc ggcatgattg acattcatat
     1741 ccacggcggc tatggcgcag atacgatgga tgctagcttt tccacgctcg acatcatgtc
     1801 gtcaagactg cccgaagaag gcacgacgag ctttttagcc acaacgatta cccaagagca
     1861 tgggaacatt tctcaagctt tggtgaacgc aagagagtgg aaagcggctg aagagtcctc
     1921 tttattaggt gcagaactgc tcggcattca tttagagggc ccctttgttt cgcctaaaag
     1981 agccggagcg cagccaaagg agtggattag gccttcggat gttgcgcttt tcaaaaagtg
     2041 gcagcaggag gcgggcggac tgatcaaaat tgttacactt gcgccggagg aggatcagca
     2101 ttttgaactg atccgccatt tgaaagacga atcgattatc gcatccatgg ggcacacgga
     2161 tgccgattcc gcattgctgt cggatgccgc aaaagcaggg gcgagccata tgacccatct
     2221 gtacaacgcg atgagcccgt ttcatcaccg agagcccgga gtgatcggaa cggcgctggc
     2281 ccatgatggg tttgtgacag agcttatcgc cgatggcatt cactcccacc ctttagctgc
     2341 aaagcttgct tttttggcga aaggcagcag caagctcatt ttaattaccg attccatgag
     2401 ggcaaaaggc ctgaaagacg gcgtatatga gttcggcggc caaagtgtga cggtaagagg
     2461 acgaacagct cttctttcag acggaaccct tgccggttcg atcctcaaaa tgaacgaagg
     2521 cgcacggcat atgcgtgagt ttacaaattg ctcttggacg gatatagcta atataacttc
     2581 tgcaaacgcg gccaaacagc tgggcatctt tgaccgaaaa ggcagtgtga ctgtgggaaa
     2641 agatgcagat ttggtgattg tcagcagtga ttgcgaggtg attctcacca tttgccgcgg
     2701 aaacattgca tttatatcca aggaggctga ccagatatga aagtaatgga atgtcaaacg
     2761 tatgaagagc taagccaaaa agcagccaga ataacggcag atacaatcaa agaaaaacct
     2821 gatgccgttc tcgggttagc gacgggcggc acaccggaag gcacgtatcg cgagctgatc
     2881 cgcctgcacc aaactgagaa tctctcattt caaaacgtca ctacagttaa tttggatgag
     2941 tacgccagac tttcaagcaa tgccccgaac agctatcact tctatatgaa tgaccgttta
     3001 tttcagcata tcgacagcaa gcctagccgg cattttattc cgaatggaaa tgcagacgat
     3061 ttggaggacg aatgcagacg gtatgaacag ctagtcgagt ccctcggcgg cactgacatt
     3121 cagcttctcg gcatcggccg aaacggacac atcggcttta acgaaccggg aacgtctttc
     3181 aagtcgcgaa ctcatgttgt gactttaaat gaacaaactc gccaggcaaa tgccagatat
     3241 tttccctcca tagacagcgt gccaaaaaaa gcattgacaa tgggaattca aacgatactc
     3301 tcaagcaagc gcattctgct gcttatttct ggaaaaagca aagcggaagc tgttcgtaag
     3361 ctgttagaag gaaacatcag cgaagatttt cccgcatctg ctttgcacct gcattccgat
     3421 gtcacggttt tgattgatcg tgaagccgcg tcattaagac cttgaaagga acatgctgac
     3481 ttatgaatat caataaacaa tcgcctattc cgatttatta tcagattatg gagcaattaa
     3541 aaacccaaat taagagcgga gaactgcagc cggatatgcc tcttccttct gagcgcgaat
     3601 atgccgaaca attcgggatc agccggatga cagttcgcca ggcgctttct aatttagtta
     3661 atgaaggctt gctctatcgc ctgaaggggc ggggcacctt tgtcagcaag ccaaaaatgg
     3721 aacaagcact tcaagggctg acaagcttta ccgaggatat gaaaagccgc gggatgacac
     3781 cgggcagcag gctcattgat tatcagctta ttgattcgac tgaggaactc gcggctatat
     3841 taggctgcgg gcacccctcc tctatccata aaatcactcg ggtgcggctg gcaaatgata
     3901 ttccgatggc gattgagtcc tcacatattc cgtttgagct tgcgggtgaa ttaaacgaat
     3961 cgcattttca gtcgtcgatc tatgatcata ttgaaaggta taacagcata ccgatttccc
     4021 gtgcaaaaca ggagcttgag ccaagcgctg ccaccacgga agaagcgaac attcttggta
     4081 ttcaaaaggg agcgccagtc ctattaatta aacgaacaac atatctgcag aacggaactg
     4141 cttttgagca tgcaaaatcc gtatacagag gcgaccgtta tacatttgtc cactatatgg
     4201 atcgtctttc ataaaaaaag cctccaaccc tttttaagga ttggagacat ggcgaaaatc
     4261 aaactggtct ggtgccggac gatatgtttc ttttttcgtc ttgaacttcc agatcggtga
     4321 tttcgttttg ccgttaaaac tgtcttccac tataatgtac caataataaa cagactgcgg
     4381 ttcaagatga tcccagcgga attcagctgt atccccgctc ttcacttgct cccgttttcc
     4441 gagctcttca ttggtatata cgttacattc aaaataatcg gtttccacct ttttgattct
     4501 tggcttcaaa tcaagcgaaa gggaaaattc atccttgttg ccatagatat ccgtatcata
     4561 gtaattctta tcctttacat acggagaata cgtcgatacg tgcaccatgt catttgcctg
     4621 gtcaaattga agcaaacgca aatacccttg accgccttct ggcccgccct gataatcggc
     4681 cagcatttga tgcacaagac gatccggctt cccatcacca tcatcatcca gctcatctgt
     4741 ttttctcatc gcactatgat aatgcccgct caataccatc acgacattcg ggttcggctt
     4801 tacgatttct ttgaatattt tctctccgat cgggcttctg tttccgctga ccagcaaata
     4861 ctcatgaaaa gctaaaattg ctatccggtc agggtgtttc ttcagcacct gattcatcca
     4921 cgcgatgtct tcatccgtaa tgccccatcc catgtacagc atgatataat cattgccgtt
     4981 gctagaaatc aggtcataat gtccgcggtt gtttttatag gaaccgccat aatgcaattt
     5041 tttatcaaaa cgatcgctgc caaaatattt gccaaacgcc ctgtaggagc cgtccttatg
     5101 ccccacatcg tggttgccgg ccagcacgcc gtaaggtatt ccgctcttat ccagaacgga
     5161 cattgaccga tcagcgtttt tccactgtct gatatcagcg gaatcatcta caatatcacc
     5221 cgtgtggaac acatatttga tattgagctg cttttgatta tcttttatcc attctgtctg
     5281 tttatcaaaa atatgcggat agctttcggc gtaatactgt gtatcagaca tccagacaaa
     5341 tgtgtacata tccttcgcag gaggaatttc atcctgtaca atcacattca ttttcgactc
     5401 ccgtacaaaa tcggcggcaa tcacagacgc tttcagcgta aacgatttgt catccttcgc
     5461 gacgaagctg tcaacaggct gccattcgtt tgtccgataa ttccaagcat acatcgtcac
     5521 ctttctcccc ggcaaagaac tgcccttcca gactgcttct gccagatcat tctcatcaat
     5581 tgatggatca accgtcactt caaagcgatg ataagggaaa agctctttgt tttctgtcga
     5641 tactgttttt ccatcagcag ctgatacccg ctccaattct ttattcgtaa atggggtctc
     5701 cctttccggc acaaagcttt tcggcggttc agtcagtgac gcgtgcttaa atattttcac
     5761 atgattgcgc gctgtatatt gaaatcccct ataaaaacca acatccatgg catcattcgt
     5821 cggatctttc acccgtacag aaagcttggc cttatgcgtg tcggcttcgc tgtctataac
     5881 ctccggctgg tccggatgct ctcgttcggt tttaaatatc ctctcaatca ctgttttatt
     5941 gcccgcgaga tccgttgctg tcacttttag agaatgtttt cccggcaaaa gatcagaaga
     6001 ggacgtatga tatgggagtg taatgctttc tccatctaaa gacgcttccg cttcctcaat
     6061 tttgctccat ttatcataca tatccgcctg caggataagg tttcctttat acgtttgccc
     6121 ctcggtgata ttcggctcaa tgtgaggtcc tgaattatct acccgtacaa ccaggctgac
     6181 attttccttg ccgtcgcttg cttgaatatg gtgagcgcct tcagaaagct ttgatgtatc
     6241 ccactccagc agctgtgatg taaatagtcc gtcaggcaga ttgaactgaa attgccagct
     6301 tttattcgag cgctgattat cgccaataaa gagttccttc tcaggggaca ccctctgatc
     6361 cctgatcacc gttccatccg ataacaccaa tcgggcgttt ttgactaaga agtcatcacg
     6421 gttttcagcc gtatcaaacg gagacacctt cgaacccgat cgtattgtaa tacgctgcag
     6481 ctgcttccct ttccgaagca gtgtctctgg caacggaaca gaataggtgc ggtatttatt
     6541 tgttgtatca tcgaacacct tcagcacttt gccttccatc gttaccgcgt ttttaaaata
     6601 aaggttcgtt ttcctcgtat cgaatgcaaa atatacttcc ttttccattg cgggctctgt
     6661 cacttgtttt ttcccgtcaa tccacagctt aatgcggtca gctcgccctt ctgtcgtggc
     6721 tttgagaaat tgagttcccg acagcgtgtc tctgttttca atattcatcc gcagaccgtg
     6781 cgacttgctt gtttgtttaa tatcaatcat tttgaccggc gttctcgctt cattgatccc
     6841 gtccccggcc gccacataat actctagctg atccttcccg atcaattcag gcgaatacac
     6901 aatataatgg tagagattat cgttgcggtc tttttcagca agaattcgct taaacggttt
     6961 gttctcatcc gtccggtagt aaaaggccgc tgttttcact agacttcggt cccgtatgtc
     7021 agcccgcagc tcaatgcttt cagcagggcg gacaggcttg cggtcagtca aatcctcaat
     7081 gaccggcttt tctttatcga gcttgatttt tcgtttctgc tcgggcacct gtgcctgtaa
     7141 taccgttccg ggagacggat tcttttcccc gattgaaatg ttcagaagtt ctgcggttcc
     7201 gttcaacgga tacttataaa gcactgatga cagccggcgc agcgcatgtt tccgataatg
     7261 cgcaaccgaa atgtcctttc ctgtattcgt tgatatcaca acggcccgcg gcctcgtatt
     7321 ggccataccc tctgtctcgt ctatcaccgc gagatttttt ccttctttta gttgtgtctg
     7381 ataataacga ttgaaatcct ctgacgtcaa ttctggatgc ccggcaggct tcagccagac
     7441 gacaaacgtt tcgccggatg gtatcaagat cctttcatca ggtctccaaa tcagatcgga
     7501 gtcaggccct tcttttgggt agcggtaacg gatatggtag tctttaaaat caatcgttct
     7561 gtcagtcgta ttataaatct caataaattc ataaccgtct gcgcgtccta tattcttcgt
     7621 atcaaccgct agctctgtga tcagaagctc cggaatatgg gcaagatcag cctggtatcc
     7681 ttcaagcttc agtttcttcg tctccgactc aacccgctgc ttcccattcg acatcacaat
     7741 gtaatactca agctcgctgt tccaaatcaa acgtttcgga atttgtgcca aaaacttgcg
     7801 gaccgctccg ggggtcgggt ccatcggcac cattttgtag cccagctcat tactttgttt
     7861 ataaaaaaga aaggcggaaa atgcttgata cgaattatcg cgaacttgag cctcaatcat
     7921 tagattgctt ctcatttcag ctttcacatc aatttgagga ggattttcaa gcaagggtat
     7981 gtaatgaggc gtttgaaata gttcctgctg tacaacagga acagctttcg attcatgatg
     8041 gccgccagac aaaacggaaa gaaaagacag taatatagaa gcaataaccg tgtatttcct
     8101 catcaaagca cctccctttt catgtatttt gcgtctgaac agggaagctt atgagttcat
     8161 ttttgtgcat aaagaacaaa aaaacgtctg cctcttgaaa attccactat tccccagtaa
     8221 actaaggata gttaaccagt taacaattaa atcagagagg caaattgatg aacaacagca
     8281 ttcatgatga attatttcaa gctatacaac aattcgcatt aaaaagagat aaacgcgtct
     8341 ggcaaaaggt gcagattccg tcctcacaac atctcgacca cctcaaaaaa gactggacat
     8401 tgacccagct tcacattgtt tcctgtttac ataccagcaa aaatgtgaat aacagcttct
     8461 tagcatcccg cttacatatc tcaaaagcag ctgtttcaaa agcaattcaa gctttgttga
     8521 aacataacat cattacagtg acaaaaaagc cgggcaacaa aaaagaaatt ttttatacgt
     8581 taactgaaag cggcaaagaa ctggcggggt tacatgaaca gcttcatcaa aaagcaaagg
     8641 agcaatacaa acagctcttc aatgaatttt caattgatga gttgaaaaca gtgactgcgt
     8701 ttattaactt gtggatcaag catatgtaaa aaagcctcac ccgcacggga gagacctttc
     8761 catattatta agccctgtca aatacaatat gaagtgagac gggtccgcgt gtatacagac
     8821 cggactcagc ataacaaaaa tcttcctcta atctgatatt ccgcatctta tccagcacaa
     8881 tattagctac aatttcaatt tcggttttgg caaaagctgc tcctacacag ttatgaatgc
     8941 cggatccgaa agcgagatgc cgggcggcgc cgctaaaagc gctcttgatg ccaagatctt
     9001 cccgatgaat attaaacacg tcaggctgtt caaatgcttc agggtcccgg ttagccgcac
     9061 cgatcataca aaaaacaatc gtatcttttt tgatttccat accgccgacc actgtatctt
     9121 gggacagctg ccgcggtatc agctgaaccg gcggtttata acgcaatgtc tccgcaatgg
     9181 ctctcggaac taacgaacgg tcagccaaaa catcattcat ctgctcagga ttgttgagca
     9241 aatggtagat catcagtgcc agcgtcttat cagccggttc cgttgcggct aacagcacat
     9301 taagaatcag tgcgagtata tccttgtccg acagcgccat gccttcatat tcagaagtac
     9361 ataggatcga aattaaatct gatcccggat tgacgcgacg ttctttaatg accggcatca
     9421 agtattggga aagctgttcg ctgcaccata acgaatgtgc ccgcgcttca ggagattgag
     9481 agatactcgt gataaaatcg gcaactccgc tgtgccactc agagattttt tcatggtctc
     9541 ttttatccag cccgagcatg tccatcgtga cgcacaccgc aaacgtcttt ccaaaatcat
     9601 tgacaagatc aattttccct ctttcaagat aaggcgctaa caagttttct gcattttgtt
     9661 taatcaatgg agacagatga tccagtgcgt caccgataaa gcttctcact acaattcttc
     9721 ttttggcaga gtgttctttt ccatgcattt gggccagcac agggcctcgc atgactggtt
     9781 cggcacgctc aacaagtgat ttcgtcgtga agatatccgg atgctgaagg atatagcgga
     9841 catcatgata gcggctgata aaataactgt ctatcgactc ttcataatga accggatctt
     9901 cctcccgcag ttgtgaaaaa taagcatatg gattgttttg aaattgatca gaaagcacac
     9961 taaacaattt aatcgattgg ctcatgtttt actcccccta tcatccttca catgtgatcc
    10021 gtttctcaga aagcatctgc gccatttcct gtacaatgag atacccttga ttcggccgca
    10081 tacaaataga aaattcatgg ttactgatct tctcaccgag cttccacgga cgatgataag
    10141 caaggagcgt ctcttccacc tctaaaatat ccggagctcc gataaaaaac ggcagctcag
    10201 ctatgacata ttccacagcc aaattcagca tatcctcact gacttcttcc atcatcaaac
    10261 tgacgccccg tgcacgcccg attatcgctt cacgagacat gtccaaacaa gcatgtcgaa
    10321 aatgaggctg atcaaaaaat gcatgttcaa cttcttgtct caacagctgg taggctttgt
    10381 tatccataaa atcagaaaat gtatgaatcg ccttcggatc cccgccatga gccacaagag
    10441 ctctttctgc aaatctcctg tttcgtgata cctctttcct tacttttcgt tcagcctttc
    10501 ctctcggagt tccaagcgct tctagaagat tagcggcctc atgccctgca agtaaaactg
    10561 aaacgctttt aaattgagct ttcgcccatc caattaatct gtaaatataa tcctctgaaa
    10621 acctgctgtt aaatgggctg attcccacca aaacatgcct gcgccgttca aatatttctc
    10681 tgcagttttc tgttaatgcc tcagcaataa aatgcacaga ccttctttcc gttaccattc
    10741 cggtcatctc attcacccct aaaacttatc ccgctttaag tcatcaccct caaatacaag
    10801 atggaatagc tagaacaact gaacaagacg aatggcaggc atcacttaaa gtttccaaat
    10861 gttttttaag attttaataa tcattttcaa tacccatatc atgataaatg tttactagta
    10921 aacattagtc attttatccc ttttccttcc aaacgtcaat atgatctgtg cccaaatatt
    10981 tgaaaataaa tgtaaacatc acattttcca cacacttttt acacgcatat tcagcatgac
    11041 atatcaacaa atagtctaaa caccaacaat tgacaacgaa aacaagaaaa gataaaataa
    11101 aattgttcac gagtaaacga tttgttttat tgtttcatcg taaactatta ttcctaagaa
    11161 agaaggtagc ctatgtctga tttgacaaaa cagatgatat acgacatata cgtgagactg
    11221 ctgcacctta atgaacaaaa agcgaacact tcacttcagc aattttttaa ggaggccgca
    11281 gaagaggatg tagctgaaat tcccaaaaat atgacaagca ttcacgtcat tgactgcatc
    11341 ggccagcatg aacccattaa caatgcgggg attgccagaa aaatgaactt atcgaaagcg
    11401 aatgtaacga aaatcagcac aaaactgatc aaggaagaat tcattaacag ctatcagctg
    11461 acagataaca aaaaagaagt ttattttaaa ttaacccgta aaggcagacg gattttcgac
    11521 ttacatgaga aactgcataa aaaaaaggag ctggcttttt accaattcct cgattcattt
    11581 tcacaagaag aacaaaaggc tgtattgaag tttctagagc agttgacgtc aacacttgaa
    11641 gcagaacaaa ccgatgggac tccggacaaa cctgtaaagt aaacaaaaag gcggtgtaca
    11701 ctttggctca tacaaaatca aaggcagtat tgatcttata cactgtttgc ttcagtgcat
    11761 tttttgcatc tttaagccag aacatttatt cacctattct tccgatcatt aaagaatcat
    11821 tccatgtttc cacagctatg gtgaacctgt cagtctcagt ttttatgatt gtgacagcaa
    11881 taatgcaaat tatattagga gcgatcattg attttaaagg cgctcggatc gtcttgatta
    11941 ccggtattct ggcaacggca gcagccagca tcggctgtgc ggtgactact gactttacct
    12001 tgtttctgat attcagaatg atacaggcag ccggttccgc agcactgcct cttattgctg
    12061 ccacaacgat cggacagctg tttacaggaa atgaacgcgg gagtgcaatg ggaacgtatc
    12121 aaatgctcct gtctgtcgca ccggctattg ctccagttct aggaggattc ataggcggag
    12181 cagccggata cgaagggatt ttttggatac ttgcggccat ctctatcgtt ttgctggtga
    12241 caaacagcat catctttcct aaagattctc caactgaatc tatgcagcaa gccaaaggca
    12301 atgtgttcgc tcattataaa tcaatattta caaatcgaac agggaacgtc attttgactt
    12361 taagttttgt tctctttttc atttattttg cagtaattgt ctacctccca atattgctga
    12421 cagagcatta ccatatagat gtgggtatag caggactgtt atatttgccg ctggcgctga
    12481 gcacgattgc aggtacgttt ctgtttaaaa gaatacaggc aaaaatcggg ctgcacacct
    12541 tgtttatcgg aagcaatgtg attgccgcct gcagcatcat tttatttgct gttacacatt
    12601 ccgtttctct cgttctcatg gctctgacgc tggcactgtt tggcatctcg atgggggtta
    12661 ttcctccctt gtactctaca atgattacta atgaatttga gcacaacaga gggagtgcaa
    12721 tcggaatgtt taactttatc cgatatacag gcatggcagc aggtccgatg gtatctgcct
    12781 acttgctcac aatgatgccg tctgccattt cctttagcct cctaggcctt ggatttgccg
    12841 cattgagctt ttgccttctt ccgccaatgt tttcgccgca gaagcgcacg aaacaaaaaa
    12901 agcaccacat gtaaaaaagc tgcctttgcg ggcagctttt ttttattttt ttctaagcgg
    12961 ctctaaaatg cctttttgaa tcagcaaatg gaagaccgac aggataacgg atgcccatat
    13021 cgctgtgccg aagccgtcaa tttgaaagct gtcacccata atggacgcgg tcatcataag
    13081 cgtgatggcg ttaatcacaa acaaaaagag cccaagcgtc accatggtga ccggcagtgt
    13141 aaagataatt aaaagcggtt taatcagcac gtttaagatc gataaaatga ggctggcgat
    13201 aatcgctgcc ccaatgctgc tgatatggat ggagtcaata tatccatcaa tgacgattaa
    13261 taacaatgca ttgactaaaa tgctgactgc ccattttacc atgtcatttc atatcccttt
    13321 ctgacgggac gataaaaatc caaatgatat aaatgagcaa aaccggcaag acacttgtca
    13381 taatggctaa gatgacagtt atgactctga ggagtgatgc gtcccaattg aaatattccg
    13441 cgagacctcc gataacaccg gcgattttct tatttttttc tgagcgataa agcttattca
    13501 ttcgatcacc tctgtgagta ctttagtttg atggcgcctg ttagtgattc tgagaagacg
    13561 gtgatgtttt gatcatgtgc ctgatttgaa gtgaacatca tttctttttg aatcgtatca
    13621 tttttttcct tcagcatctc tacatccatt aattcatggg acagcgtacc aagattgctt
    13681 ttcagctctg ccttcactgc gagatcgtcc ggaattgcaa gctctacatt tccagtcgtt
    13741 gtttttgcat aaatggagcg gcagtctgat tctgttacgt taatcgcaat atttccgtta
    13801 aagctttgaa cgtcaatgga ttcgcttttc cctcggagat cgatcaatcc gttaatggtt
    13861 tccgcttcta tcgtaccgca gctgtggctt gcgagcttaa tttgcccgtt ggccgtttca
    13921 gctatggctt tttcggctgt taaatacgag aacgacagca cgccgtttgt cgttttcgct
    13981 gagaactctt ttacatgtaa atgttcccct ctgactggac cgttaaacag cttcacccga
    14041 atcttatcat actccttctg aggaatatac aaagtgacat tcgttttcat cgtctttttc
    14101 tcagtacgga taaaaaactt attacctttg atttcacatt caatatgctg aagaaatgcg
    14161 tgtctcgccg catcctggct gtcagcgcga tataccttcg cctggcattc cgctctgata
    14221 tcgtcatctt cccaagggac gatatttacg ctgccattgg caatttgcag ctcaacactg
    14281 gaaaagtcag tatctttaaa ttgaaaaatg tgctgaacat catacgcatg gccaaagttt
    14341 aaatcaaggt caacttcctt gacctttttc acagcagaat caatccagtc aaacagcttg
    14401 gctcctaaag acggtttgcc gctttctttt tttgccgttg taaatggctc ttcctcgtca
    14461 tgaacgtgaa ctgagagcgc tgtgattttc tcttcttttt ccttgtagtc gctgtcaagc
    14521 ttttcaatca gtgtcaaagc ttcttgtgct gtaagctttc cttcctcaac aagcttaagg
    14581 attcgttcct tttcttgctt cattacgatc tcctccccat tgtctactta tgctgcacgc
    14641 aggaccttaa tgccctgaat cacattccaa atgataatgc caatgacaac taagaaataa
    14701 ataaccgctc ccccgatgat tacaaataca ggaagcaagc tgtctccatc aatcgcaacg
    14761 gctccgccaa gtaaagcaat aaaaaggaac agccagccga caaacggaac aatgtgagaa
    14821 ataagagagc gtatcgcatg gcgttttgtt tctttctcat ttacaacaaa atatgcgaca
    14881 atcggcacaa tgattggcgc aatgaacaca ctgaaataac aaagtgatgc aataatagct
    14941 tgattacggt tcaattcatt ccacactcct attgtgaatt gtccatgaca aaagatcagg
    15001 gacgttttac ttatttatac gtttaaaatc tcttcaggtt tcaaattcat tctttagaca
    15061 tgctccgatt tacggaaatt ggattttaaa aagttttaga agtagaatct tccggctata
    15121 ccgattacaa tatgtaaaaa gcttacggca accaaggagg ctggacaagc aatggagaaa
    15181 gatcccagtg actatacagt aacacaagaa tcagtgttaa agctgattca tgaacaaaaa
    15241 agaatgaatc gtgaaatgat cgccgagctt gagcagattc acggaccctt cccgatctct
    15301 cacgatatcc aatatataaa agtgctgctc gacagcagca acacgcatat tgttcaagat
    15361 ttaatgagtg taagtaagca gctgtataag aagactttgt aattgcggaa aacatatcat
    15421 tcattataac tgaaacaaag ctaaaggtta gatgacaata tcttgccttt tttgttttga
    15481 aaaaacaagt gattccctgg ctgtcacaaa atgattgtaa caaaaaaagc ctgccggcac
    15541 atccagttaa tggactctgt cggcaagctg taactatcag aaagagatag ccgttcaaaa
    15601 ttaacgtaac aattgaagca cgttttgcgg ctgttggttt gcttgagcaa gcatcgcttg
    15661 agaagcttga gaaagaatgt tgttctttgt gaaatcgctc atttctttcg ccatgtcaac
    15721 gtcacggatg cgagactcag cagctgttaa gttttcagaa gaagcaccaa ggttgttgat
    15781 tgtgtgctct agacggtttt gtaccgcacc aagtttagca cgttggtttg aaacacttgt
    15841 aattgcacta tcgattttaa caatctcagt gtcaaaacta aaatcatctg ctgaaacatc
    15901 gatacctttt actcctaaag ttgttgcatc catgttacca attgtaacat taatattttg
    15961 gccagcattt gcaccaattt ggaatgtaaa tcctgctgtt tcactaccgt ctaaaagttt
    16021 ttttccgtta aattcagtac gttgagaaat tccatcgatc tcttcagtta aagcatccat
    16081 ttcatcttta attgcagtta aatcttcagg ttgctgtgta cctgtgtttc ctgcttgaac
    16141 agtaagttca cgcatacgtt gaaggattgc atgggtttca gtcaatgcac cctcagctgt
    16201 ttggataaga gaaattccat cttgagagtt tttagaagcc atttcaagac ctctgatttg
    16261 tcctctcatt ttttcagaaa tcgcaagacc cgctgcgtca tctcccgcac ggttgatgcg
    16321 aagaccagaa gaaagtttct ccatgttttt tgagctcgca ctgttgtttg aagacaaacg
    16381 gtttagtgtg ttaagcgctg caatattgtg gttgattctc atgtgaaaaa tacctccatg
    16441 tgtatatgtt tttgaaatca aagacttcct tttctttgat ttctggcgta tcagattcca
    16501 ataaagcttc taacctatgt agattcagtt attgcttaag gatgccttta agctccttaa
    16561 tagggtttgt ctgcttaatt tggaaatcat catccgcctt tcaattcata tatcgacagc
    16621 aatttgtaaa tgtttaggcg ttttcccaaa gaaattttac ccaaagacga ttctaaacct
    16681 attatgccgt aaagaaaaag cttgcctgct aagcccaagg atggacttgc tgacaagctg
    16741 tcccctctta acagagggtt ttaagatgta gctgtttctt tcgcttttaa gagcgatttc
    16801 atgcgtgttt tgtcacgttc gataacaggc ttcaaataac ggcctgtata cgattcttcc
    16861 acttcagtga tttcctcagg cgttcctgac gcgacaatgg ttccgccccc ggctccgcct
    16921 tccgggccca aatccacaat gtaatcggcc gtcttaatga tatcaagatt atgctcaata
    16981 accagtacag tgtctccgtt gtctaccaac cgttgcagca cgacaagaag cctggcgata
    17041 tcgtcgacat gcaaacctgt cgtcggctca tctaaaatgt agagcgtgcg tccggtcgag
    17101 cgtttgtgca gctctgatgc gagcttcacg cgctgcgctt ctccgcctga caaggtcgtc
    17161 gccggctggc cgagcgtaat ataacctaaa ccaacatcat aaagggtttg gagcttgcgt
    17221 ttgattttcg ggatattttc aaagaaagaa agagcatctt caaccgtcat atcaagcaca
    17281 tcagagatgc tttttccttt gtacgtcact tcaagcgttt cacggttata gcgtttgccg
    17341 tgacacacct cgcatggaac gtatacgtca ggaaggaagt gcatttcaat tttaataatc
    17401 ccgtctccgc ggcaggcttc acatcgtccg cccttcacgt tgaagctgaa acggcctttt
    17461 ttatagccgc ggaccttcgc ttcatttgtc tgcgcgaata catcacgaat gtcatcaaat
    17521 acaccggtgt atgtcgcagg gttggatctc ggcgttcttc cgattggcgc ctggtcaatg
    17581 tcaatgactt tatctaaatg atccaaacct ttaatctctt tatggctgcc gggcttcgct
    17641 ttcgctttat gaagcttttg cgccagcgcc ttatgcaaaa tttcattaac gagtgtactc
    17701 tttcctgaac cggaaacacc tgtaactgct gtaaacgtcc caagcgggaa cttggcattc
    17761 acttttttca ggttgttttc tgatgcacct ttaatttcaa tgtaacgtcc gtccggcttt
    17821 cttctttcag gaggcaatgg gataaacttt ttccctgata aatagctgcc cgttaatgag
    17881 tttggatctt ccatcacttc ttccggcgta cccgcagata tcacctgtcc gccgtgaatg
    17941 ccggctcccg gtccaatatc tattaaataa tctgctgcca tcatcgtgtc ctcatcatgt
    18001 tcgacaacaa tcagcgtgtt cccgaggtct ctcatatttt tcagagcgct gatcaagcgg
    18061 tcgttatcac gctgatgcag accgatagac ggctcatcta aaatataaag cacaccggat
    18121 aaacgcgagc caatttgagt cgccagcctg atgcgctgcg cctctcctcc ggacaatgta
    18181 cccgccgccc tgctcaatgt caggtaatcg aggccgactt tgtccagaaa gcttaagcgc
    18241 tccacaattt cgcgcaaaat caaattggcg atctgcatat ccttctcaga aagggtgaga
    18301 tctttaaaga aggcaagtgc gtcggcgaca gacagctcgg taatttttcc aatgtggcga
    18361 ccgtcaatca gtacggcaag cgcctctttc tttaaccgat agcctttgca cgtcggacaa
    18421 gacttctgag acatatactg ctccatttgc tcacgtatga aatcggagcc tgtctcctta
    18481 tagcgtcttt caatgttgcg caatacgcct tcaaattgaa tttcaccttc gcggatttgt
    18541 ccaaaatcat tttcatatcg gaaataaatc aggtcatccc cgctgccgta cagcacttta
    18601 tccagttgat gcttcggcaa atctttgacc ggcacatcca tatcaatccc gtagtgggtg
    18661 cagactgcct caagcagctg aggataatat tgtgagctga tcggtgtcca aggggcgacc
    18721 gcattctcct tcaatgacaa atcttggttg gggatgacaa gatcggcatc cacttcaagc
    18781 ttcattccga gaccgtcaca cgtcggacac gccccgaacg gactgttaaa cgaaaacaga
    18841 cgcggctcaa gctcaccaat tgaaaatccg cagtgcggac aggcatgatg ctcgctgaac
    18901 atcagctctt cctcaccgat gacatcgatc ataacccgtc cttcccctaa acggagcgct
    18961 gtttccaatg aatctgacag ccgggctgcc acgccttctt tcacgacaat ccggtcaatg
    19021 actacctcaa tggaatgctt cttgttcttt tctaattcga tatcgtcgga aagctcagcc
    19081 atctcgccgt caattctgac tctgacatag ccttgttttc taatctgttc aagcactttg
    19141 acatgagcgc cttttcggcc tgagacaatc ggcgccagca cctgaagctt cgtccgttcc
    19201 gggtattcca gaattctgtc caccatttgc tcgatggtct gggatgtaat ctcaattccg
    19261 tgttccggac aatgaggctt ccctactctc gcatataaaa gacgcagata atcataaatc
    19321 tcagttaccg taccgacagt agacctcgga ttgcggctcg ttgttttctg atcaatgctg
    19381 atggcgggag aaagcccctc aattgcatcc acatcaggct tatccatttg ccctaaaaac
    19441 tggcgggcat aagcagacag cgactcgaca taccgtctct gtccttcagc atatatcgtg
    19501 tcaaaggcaa gggaggattt acctgatccg gacaaacccg tgacaacgac aagctgatct
    19561 ctcggaatcg ttacatctat atttttcagg ttatgcgccc tggctccctt cacctctatc
    19621 cgatccatag ccatttgttc atcatccttc cgcttttagc tctaaaagta aatcgcgaag
    19681 ctccgcggct ctttcaaagt caagcgcctt ggcggcttcc ttcatttcat gctccatctg
    19741 ttcaacgact ttctggcgtt ctttcttcgt cagtttcgac agcttcggcg cggcttttgt
    19801 tttgtattcc gctttatcct cagctgctac tgtggcacga atgacatcgc gaatttcttt
    19861 atttatcgtt ttcggcgtaa tgccgtgctc ttcattaaac cgctcctgct gctcgcggcg
    19921 gcgttttgtt tcattaatcg caatttccat agacttcgtt attttatcgg cgtacataat
    19981 gacgcggcct tccgcatttc tcgctgcccg tccgatggtc tggatcagcg accgctccga
    20041 acgaaggaaa ccttccttat ccgcatccaa aatcgcaaca agggatactt cgggaatgtc
    20101 caaaccttcc ctcagcaggt tgatgccgac aagcacatcg tacttgccaa ggcgcaggtc
    20161 gcggataatt tcaatccgtt caagcgtctt gatctcagaa tgcagatagt ttactttaat
    20221 gccgatttct tttaaataat cggtcagatc ctctgacatc ttcttcgtca aagttgtcac
    20281 aagcacccgt tcattccgct cgattctagc ttgaatttcg ccgatcaagt cgtcaatctg
    20341 accttcgatt ggacggacgt caataagcgg gtcaagaagc cccgtcggac gaatgatctg
    20401 ttcgaccatt tcatctgtat gttcaatctc gtacggccct ggtgttgctg atacatacac
    20461 gatattgtgc atatgctttt caaattcctc aaaacgaagc ggacggttat caagcgctga
    20521 tggaagccgg aagccgtgat ccacgagcac ctgtttccgc gcctggtctc cgttaaacat
    20581 gccgcgcacc tggggaattg tcacatgcga ctcatccacc acgatcataa aatcgtctgg
    20641 gaaataatca agaagcgtat acggagttga acctggaggc cgcagcgtca aatgtcttga
    20701 atagttctcg atgccggagc agaaacccat ttcacgcatc atttcaa
//
