LOCUS       NZ_CP028834            22154 bp    DNA     linear   CON 25-MAY-2024
DEFINITION  Streptomyces sp. M2 chromosome, complete genome.
ACCESSION   NZ_CP028834
VERSION     NZ_CP028834.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. M2
  ORGANISM  Streptomyces sp. M2
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8718751)
  AUTHORS   Worsley,S.F., Murrell,J.C. and Hutchings,M.I.
  TITLE     The chemical ecology of Streptomyces-plant root interactions
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8718751)
  AUTHORS   Worsley,S.F., Murrell,J.C. and Hutchings,M.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-APR-2018) Biological Sciences, University of East
            Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom
            (Great Britain)
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 197.99x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004104505.1-RS_2024_05_25
            Annotation Date                   :: 05/25/2024 03:18:12
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,020
            CDSs (total)                      :: 7,927
            Genes (coding)                    :: 7,816
            CDSs (with protein)               :: 7,816
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 111
            CDSs (without protein)            :: 111
            Pseudo Genes (ambiguous residues) :: 0 of 111
            Pseudo Genes (frameshifted)       :: 39 of 111
            Pseudo Genes (incomplete)         :: 91 of 111
            Pseudo Genes (internal stop)      :: 7 of 111
            Pseudo Genes (multiple problems)  :: 25 of 111
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:04:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1902503
            Orig. end                         :: 1924657
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP028834.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Matthew Hutchings,
            School of Biological Sciences, University of East Anglia, Norwich
            Research Park, Norwich, NR4 7TJ.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22154
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22154
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22154
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12154](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12154)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            445..1695
                     /locus_tag="DBP13_RS08840"
     CDS             445..1695
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675708.1"
                     /locus_tag="DBP13_RS08840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_128801621.1"
                     /transl_table=11
                     /translation="MSLLRQLRYPTVTQLVACAQSLAGTRPGLCTLRQVGVSRAGRPLH
                     LLSVGRARRAVLVVAGAHANEPTGACTVLSLAERVLAERELRAETSWHFLLCADPDGAS
                     LHVTPAPRSLYEYHLGFFRPSAEEQPEWSPSVLPPHLLPPETRALTEVIDELRPYLQVT
                     LHGTDLGGSWVQLTEDIPGLAEPFAKSAAQLHIPVETGASDAAGWSASGPGVHVMPSVG
                     AGAAYPSMPDDARNSTWYATHRYGGLTAVVEVPMWASDLVDDPAPHPAPAAEIGRLARR
                     LQCDALEVERVLADALPRLEGVEGPLLRAAQWVLDLVPGLAADWIHTPPADNTMAYVSS
                     VDAFGRRLPLRAAAMLLRVLRETGDPTAPGLERLVETWSDAFAERFRARWVPLEHQVEH
                     QSRTVVTAARCARDRAA"
     gene            complement(1744..2163)
                     /locus_tag="DBP13_RS08845"
     CDS             complement(1744..2163)
                     /GO_function="GO:0004867 - serine-type endopeptidase
                     inhibitor activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983596.1"
                     /locus_tag="DBP13_RS08845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SSI family serine proteinase inhibitor"
                     /protein_id="WP_108006798.1"
                     /transl_table=11
                     /translation="MTISTRAKTLRGGLLAAAALLVAGAAPAQAVTHGFPPNNWLYLTV
                     AKGDARAGHRHGTLLLCDPPAGHARAAEACGELAAVDGDITRIPVKDTFCPMIYAPVTV
                     HARGQWSGRTVDYTERFSSACFMTARTGSVFALDD"
     gene            complement(2160..3524)
                     /locus_tag="DBP13_RS08850"
     CDS             complement(2160..3524)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133690.1"
                     /locus_tag="DBP13_RS08850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_108006800.1"
                     /transl_table=11
                     /translation="MWRCALPPLLRYPTVDELGARAAAMVARRPADARLRRVGTSRAGQ
                     PMWLLSIGHGSRQALVVAGPHANEPVGGGTVLRLAERALADPRFTEGADATWNLLLSLD
                     PDGLRRNEGWLQGPYTLGRYFRNFFRPGFLEQPEWLPDGAAGAALPETRTLLELQDELR
                     PFLQCSLHGVDVGGGFVELTHDLPGLAGRVAHTAARLGIPRELGPYDTLYWPSLGPAVY
                     RIPPPQIGDLAAAITEAAVESTWFHPHRYGTVTAVVEAPMWGVAAVEDGSPPADAAAVL
                     RTVSHTLRRDTRLLEALLARLRPHLAGTPDVAHLLAPVDDYLLVCPGLADTWDPDIADG
                     ARPLPPLSNAHLAALRIAGRRLALRTAGLLHQLVTAAGRDPAGVLPDLERFIEQWCADY
                     RDTIGARWIPVARQVEYQSRVVLAAFELAGRYAPACSRSGESGWGSQAAVPMHLE"
     misc_feature    complement(2556..2558)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3606..3617
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            complement(3673..4224)
                     /locus_tag="DBP13_RS08855"
     CDS             complement(3673..4224)
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="DBP13_RS08855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_128801622.1"
                     /transl_table=11
                     /translation="MTSSFEFNTYPARLSDAERDKALKVLRDGVAMGRLSHDTFIHRME
                     LALAARRPDELAVLTADLPQESRLSRVVFGTVEAVSGFTVRLRRAWQAERLPKLLLPHP
                     GNGHPLRIGRDPANGLRLTHETVSRTHAELTRQGGMWVLRDLGSTNGTTVNGRRVIGAA
                     VVREGDQVGFGRMSFRLAVD"
     misc_feature    complement(4256..4271)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.71"
                     /tool="antismash"
     gene            4400..6145
                     /gene="treZ"
                     /locus_tag="DBP13_RS08860"
     CDS             4400..6145
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="DBP13_RS08860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_108006804.1"
                     /sec_met_domain="Alpha-amylase (E-value: 4.6e-11, bitscore:
                     41.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQAGRVTLRCDGATRALERDPQREGWWRADAEAHDGSR
                     YGFALDDGPVLPDPRSRRQPDGPDGLSAVVDHGRYAWRTEWAGRPLPGAVLYELHVGTY
                     TREGTLDAAAERLGHLVELGVTHVELMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHLGPSGNHLPAFGPYFTDTHHTPWGSAVNLDAPGSDEVR
                     AYLLGSALAWLRDYRIDGLRLDAVHALADTRAYTFLEELSTAVDALGVELGRPLFLIAE
                     SDLNDPRLITAREEGGLGLHAQWNDDFHHALHTALTGESQGYYGDFARAPLAAVARTLT
                     GGYFHDGTYSTFRGRHHGRPLDRTRVGAHRLLGYSQTHDQVGNRALGDRLAATLSPGLV
                     ACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELAEAVRRGRRREFAAHGWAEE
                     DVPDPQDPATRDRSCLDWTEPDREPHARVLDWYRALIALRHAQADLTDPDLADTKVAHD
                     EHQRWLAFRRGDVRVAVNLSKEPAAIPLGPRHARVLAAWEPVEAPGADGVLHLPGESCV
                     VLLQS"
     gene            complement(6196..7134)
                     /locus_tag="DBP13_RS08865"
     CDS             complement(6196..7134)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431957.1"
                     /locus_tag="DBP13_RS08865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_128801623.1"
                     /sec_met_domain="APH (E-value: 1.8e-22, bitscore: 79.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVSSLLKDGGGGAAGPEVRPVAEGAGHSTWW
                     VGGRHVLRLAPDREAALRQRRELRLRDVLRPYLPVAVPTSVAQGEWAPGLPYTLDTKVP
                     GGTGEDHDVSAVGEADLAGLLGGLREVPARQAETLGVPRVAPRSLEALRRAAQHAAERL
                     GAADEFDPARLHQLTGAAAVQLAAQPCTAVLVHHDLRGEHLVVSADGRVRGVLDWTDAA
                     VGDPAEDIAGLAQAVGSPAAVRAATLAGYGARPCLRGLWLARCDAAARLAEALQSRDTD
                     ALPLLRLRLRRAWEAILLERVTDLRGGDADI"
     gene            complement(7184..8311)
                     /locus_tag="DBP13_RS08870"
     CDS             complement(7184..8311)
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="DBP13_RS08870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_128801624.1"
                     /transl_table=11
                     /translation="MTGSTRVPFTADDYRSRMDRAARAAADAGLDGLLVAPGPDLVWLT
                     GYAPTAVTERLTLLVLAQGRAPVLVVPTLEAPDAAQAPGAPALNLRDWTDGKDPYAATA
                     ALLSGAGRFGISDNAWAMHLLGLQRSLPGTSYDSLTEVLPMLRAVKDAAELELMAAAGA
                     AADQAFEEIRKVPFAGRRESEVGADLADLLRQFGHSQVDFTIVASGPNGANPHHEVGDR
                     VIEFGDMVVLDFGGLRDGYGSDTSRTVHVGEPTEEERRVHDLVREAQEAGFRAVRPGAA
                     CQEVDRAARAVIAEAGYGEYFIHRTGHGIGVTTHEPPYMIEGERQPLMPGMCFSVEPGV
                     YLPGRFGVRIEDIVTVTEDGGRRLNDTTREMVIVD"
     gene            complement(8471..9094)
                     /locus_tag="DBP13_RS08875"
     CDS             complement(8471..9094)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385486.1"
                     /locus_tag="DBP13_RS08875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysE family translocator"
                     /protein_id="WP_108007473.1"
                     /transl_table=11
                     /translation="MMSTLLAFLGACTLIAASPGPSTVLIIKQSLRSRRSGFLTVLGNE
                     TGVFTWGVVAAFGLTALLAASEVAYDVMRIVGAVVLVGFGIQALRQARRAGGAPEDTAW
                     EGTRKSGWATYRGGLLMNLANPKAAIFAMSFLPQFVPEGAPHLATMVGLSALWAVYEVG
                     YYGLYVWFVGRMRAVLSRAGVRRRLEQVSGGVLLLLGVRLALES"
     gene            complement(9239..9823)
                     /locus_tag="DBP13_RS08880"
     CDS             complement(9239..9823)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431961.1"
                     /locus_tag="DBP13_RS08880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_128801625.1"
                     /transl_table=11
                     /translation="MEQTALRPKPMPGQDPGRGTRSGVPVRRPHAARRRARRLRALLFG
                     LFVAVVLVLSGVGIGTVGATVIGMSKLADLQRQAPQRPPALPHTGAAVPTATPAPPASP
                     APAAATLGLEAVDAQKAGALIVAVHVPGPGYSAGLVRGDVLLTFGGSRVDTAADLARAV
                     AHARPGTGVTVTVRHHSGGYQQLAVVPGFVM"
     gene            complement(10001..12154)
                     /gene="cyc2"
                     /locus_tag="DBP13_RS08885"
     CDS             complement(10001..12154)
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657047.1"
                     /locus_tag="DBP13_RS08885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_108006812.1"
                     /sec_met_domain="T1TS (E-value: 1.9e-80, bitscore: 270.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQPFELPHFYMPYPARLNPHVEQARAHSTEWAHAMGMLEGSGI
                     WEQSDLEAHDYGLLCAYTHPECDGPALSLITDWYVWVFFFDDHFLEIFKRTQDRAGGKA
                     HLDRLPLFMPMGPDTPMPEPQNPVEAGLADLWTRTVPAMSADWRRRFAVATEHLLNESL
                     WELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYATAEVPAAVAGSRPLRVLMETFA
                     DAVHLRNDLFSYQREVEDEGENSNGVLVLETFFGCTTQEAADTVNDILTSRLHQFEHTA
                     LTEVPALALERGLTPPEVAAVAKYTQGLQDWQSGGHEWHLRSSRYMNARAQSANPWHGP
                     PGPGSSADIGALLAAAGAERLRAYTHTPYQRVGPSLLPDFDMPFQVEVSPHLDAARPRL
                     TAWMHAMGMLEEGVWDEDKLAACDLPLCSAGIDPDATPEALDLSSRWLAWGTYADDYYP
                     LVYGNRRDLAAARLTTRRLADCMPLDGEVAVVPVNGMERGLTDLWARTTAGMTPDERRT
                     LKDAVNAMTESWVWELSNQLQHRIPDPVDYLEMRRATFGSDLTLSMCRMGYGPAIAPEV
                     YRSGPVRSLENAAIDYACLVNDVFSYQKEIEYEGEIHNAILVVQNFFGVDYPTALGVVH
                     DLMTQRMRQFQHVAAHELPVVQQDFGLSEQERAAVDGYVRDLQHWMAGILHWHRSVDRY
                     KAGYLARRAHGFVPGRPPAVPVL"
     misc_feature    12135..12150
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            12321..13595
                     /locus_tag="DBP13_RS08890"
     CDS             12321..13595
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071446.1"
                     /locus_tag="DBP13_RS08890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_128801626.1"
                     /transl_table=11
                     /translation="MDHQPRTLSRRTALASLAGAALAGTAAVPAAASGLARSAQGAGGT
                     HGGRTVRFATFNASLNRGTQGALVTDLSTPHNAQARNVAETIQRVDPDVLLINEFDYDE
                     HGTAISLFLRNYLAVSHNGSRPLHFPHHFTGPVNTGVASGVDFDGKNGAVTTPGSDAYG
                     QDAFGYGFFPGQYGMVVLSRFPIDTRAVRTFRHFLWKDMPGNVMPPGYYSDEARAIFRL
                     SSKSHWDVPLRIGRDTVHFLVSHPTPPSFDGPEDRNGRRNHDEIRLWADYIGGRRRSAY
                     LYDDKGVRGGLRPGARFVIAGDLNADPLDGDSYDHAVLQLLDHPAVRRPATPPASAGAV
                     EAARLQGGANTSQTGNPAYDTGDFADTAPGNLRVDHILPSKGLTPGANGVFWPTSDDPL
                     YRLAGDGTTVVTSDHRMVWQEIRVD"
     gene            13734..14207
                     /locus_tag="DBP13_RS08895"
     CDS             13734..14207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431966.1"
                     /locus_tag="DBP13_RS08895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_108006816.1"
                     /transl_table=11
                     /translation="MTEAPLRAELLLTHDVSAELERELTAGFRELGAPAVRVRRTLDHR
                     GPAELQWLALVSLPLQAFLSGLGGEAVKDGYRALRDLVARLFRRGTTAPDAAPRPLVLQ
                     DERTGLRIVLEADLPQHAYEQLTALDLSGFTVGPLHYDLARGRWRSELDEAAG"
     gene            14222..16867
                     /locus_tag="DBP13_RS08900"
     CDS             14222..16867
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DBP13_RS08900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_128801627.1"
                     /transl_table=11
                     /translation="MAYDDVHHEPDARPRPEDARARRPAAPPNRILRNCERGEAFLAAG
                     DLTAAARAFRAVLAEVGPLEDGSPEGDGGCAAPTTGAGTDSAGGSATARGADADSSPAP
                     DANAETPCGSDSDADRTAVPDADADSTAVPDTDAGTDADTAAGADADTATGADTDAHAT
                     AQSPTPTPAHLASRAHIGLGRVALRMEGADRAEREFRRAARLRPGSREPLYWLGCAAAH
                     RGAQDRDAYELAELRFTEVVEQWPGDGASLVQRAHVRVRLGRPADALADLRSAERIAPL
                     DAEARWVLAALSGATAPEVARRLGTAARSAMERAAATGPKGRPRAADDWNRAVTLLDRA
                     RQLDPGNREFALPHAVALCLSGRREDGIAVIADAARSAPTDRHLAHTLAVMSWHALAPG
                     DGTDTDAATAAAADTGTDPDTETDPDPDPDPDTDTDTDTVDDAGEDVPRTWSRCVASWA
                     GLLHDTPFWERLRAGAAERYGVVVDDKNLATLRADLQAALEALMPETGAGDRISPEALL
                     HRETEAARLLAEAGGLPLATGSAPLVCGPLRIVELGREAELGAFVSAAGDAAPALRQAF
                     SHLGFAQALLRLDRPAEALSALSGLRCPRCRARGGSGDEGRRGGGGEQSGGDTASHGRA
                     AAPRAERGAVCDPDCTRFDTRNPAYAGQAAKHVLLMRDGRSLALAARLAQGRAALTPTG
                     PDVRRAATSWQRALTHARAIGQGPEVEAIVADTALAAAKALHRAGDIDAAGSTLESAYA
                     LLGEGQHERLKGQLARVLTDRGIAQANRDMDRLEGPAADLRRAVEINPHLHRAQANLGV
                     VLRILGARMRWSGSLVGCRSRLQEALDRVTAALEHFPGDPELSQLRDLVEADLALVHSE
                     LEQGRIGGLP"
     misc_feature    15035..15037
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(19574..19588)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(21293..21303)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
ORIGIN
        1 ggcacgaggt ggaggtgaac accatgccgc tgacggcggt cgcgaagggc atggtgcacg
       61 gccgcggcgg catggtgaag gtcgtcgccg aggccggcgg cgggcaggtg ctcggggtgc
      121 atctggtggg cccgcacgtc tccgagatga tcgcggagag ccagctgatc gtcggctggg
      181 acgcgtacgc ctcggacgtg gcccggcacg tccatccgca cccgacgctg tccgaggcgg
      241 tgggcgagac cttcctgacg ctggcggggc gcgggctgca ccagcagtga gtgccgccgc
      301 tcgcgccccg ggcggcagcc gggcccgttg cgggcggcag cgaatgcttc cgggcgcccc
      361 caggagcctc ccccacggtg ttattgacac ttcgtggagg gcatggggta ctgcggttgc
      421 ggaagccggg cggacgggtc gggggtgagt ctcctgcggc agctgcgcta ccccaccgtg
      481 acgcaactcg ttgcgtgcgc acagtcgttg gccggtacga gacccggtct gtgcacactg
      541 cggcaagtcg gcgtctcccg ggccggcagg cccctgcatc tgctgtccgt gggccgcgcc
      601 cggcgcgccg tgctcgtcgt cgcaggcgcc cacgccaatg agccgaccgg cgcctgcacg
      661 gtcctctcgc tcgccgaacg ggtgctggcg gagcgggagt tgcgcgcgga gacgtcctgg
      721 cacttcctgc tgtgcgcgga ccccgacggc gcgagcctgc atgtcacacc cgcaccacgc
      781 agcctctacg agtaccacct cgggttcttc cggccctcgg ccgaggagca gccggagtgg
      841 tcgccctcgg tgctgccgcc gcacctgctg ccacccgaga cacgcgcgct caccgaggtc
      901 atcgacgagc tgcgccccta cctccaggtg accctgcacg gcaccgatct gggcggcagc
      961 tgggtgcagt tgaccgagga catccctggt ctcgccgagc cgttcgccaa gtccgcggcg
     1021 cagctgcaca tcccggtgga gacgggcgcc tcggacgccg cgggctggtc cgcctccggg
     1081 ccgggggtgc atgtgatgcc gtccgtgggc gcgggcgccg cgtacccgag catgccggac
     1141 gacgcgcgca acagcacctg gtacgccacg caccgctacg gcgggctgac ggcggtggtc
     1201 gaggttccga tgtgggcgag cgacctggtg gacgatccgg ccccgcatcc cgccccggcc
     1261 gcggagatcg ggcggctggc acgccggctg cagtgcgacg cgctggaggt ggagcgggtg
     1321 ctcgccgacg cgctgccgcg cctcgaaggc gtcgaggggc cgctgctgcg ggccgcacag
     1381 tgggtgctgg atctggtgcc gggcctggcc gcggactgga tccacacgcc gcccgccgac
     1441 aacacgatgg cgtacgtcag cagtgtggac gcgttcggcc gccgcctgcc gctgcgggcg
     1501 gcggccatgc tgctacgggt cctgcgggag accggcgacc ccacggcacc gggtctggag
     1561 cggctcgtgg agacctggag cgacgccttc gccgagcgct tccgggcgcg ctgggtgccg
     1621 ctggagcacc aggtcgagca ccagtcccgc acggtcgtca cggcggcacg gtgcgcccgc
     1681 gaccgggccg cctgagcgga ccgccggagg ggccgtccga gggggccgcc cggggggccg
     1741 ccgtcagtcg tccagcgcga agaccgagcc ggtgcgcgcg gtcatgaagc aggcgctgga
     1801 gaacctctcg gtgtagtcga ccgtacggcc gctccactgc ccgcgcgcgt ggacggtcac
     1861 gggtgcgtag atcatcgggc agaaggtgtc cttcaccggg atgcgggtga tgtcgccgtc
     1921 gacggcggcg agttcgccgc acgcctcggc tgcgcgtgcg tgtcccgcgg gcgggtcgca
     1981 cagcagcagg gtgccgtgcc ggtggccggc gcgggcgtcg cccttggcga cggtgaggta
     2041 gagccagttg ttcggtggga agccgtgcgt gaccgcctgc gccggggccg cgcccgcaac
     2101 gaggagggct gccgccgcga gcagaccgcc tcgcagcgtt ttcgctctgg tgctgatcgt
     2161 cattccagat gcatcggcac agccgcctgc gaaccccagc cggactcacc cgaacgggag
     2221 cacgccgggg cgtaccgtcc ggcgagttcg aacgcggcga gcaccacgcg cgactggtac
     2281 tccacctggc gcgcgacggg gatccagcgc gccccgatgg tgtcgcggta gtcggcgcac
     2341 cactgctcga tgaagcgctc gaggtccggc agcacaccgg ccgggtcgcg ccctgcggcc
     2401 gtcacgagct ggtgcagcag cccggccgtg cgcagcgcca gccgtcgtcc ggcgatgcgc
     2461 agggcggcca ggtgggcgtt gctgagaggc ggcagcggac gcgccccgtc cgcgatgtcg
     2521 gggtcccacg tgtcggccag tccggggcag accagtaaat agtcgtccac cggggcgagc
     2581 agatgggcca cgtccggggt ccccgccagg tgcgggcgca gccgtgcgag cagcgcctcg
     2641 agcagccgtg tgtcgcggcg cagcgtgtgg ctgaccgtgc gcaggacggc tgccgcgtcg
     2701 gcgggcggtg agccgtcctc cacggccgcc acgccccaca tgggcgcctc gacgaccgct
     2761 gtgacggtgc cgtaccggtg cgggtggaac caggtcgact cgacggccgc ctccgtgatg
     2821 gccgcggcca ggtcgccgat ctggggcggc gggatgcggt agacggcggg gcccaggctc
     2881 ggccagtaca gcgtgtcgta ggggccgagt tcgcgcggga tgccgaggcg ggccgcagtg
     2941 tgcgcgacgc ggcccgcgag gcccggcagg tcgtgggtga gctcgacgaa gccgccgccg
     3001 acgtcgacgc cgtgcagcga gcactgcagg aagggccgca gttcgtcctg gagctccagc
     3061 agggtgcggg tctcgggcag ggcggcgccc gcggcgccgt cgggcagcca ctcgggctgt
     3121 tcgaggaagc cgggccggaa gaagttccgg aagtaccggc cgagggtgta cgggccctgc
     3181 agccagccct cgttgcggcg cagtccgtcg gggtcgaggg agagcagcag gttccaggtg
     3241 gcgtcggcgc cctcggtgaa ccgcgggtcg gcgagcgcgc gttcggccag ccgcagcacg
     3301 gtgccgccgc cgacgggttc gttggcgtgc ggtccggcga cgacgagggc ctgccggctg
     3361 ccgtgaccga tggaaagcag ccacatcggt tggcccgcgc gggaggtgcc gacgcggcgc
     3421 agacgagcgt ccgcgggacg gcgggcgacc attgcagccg cccgcgcgcc gagttcgtcg
     3481 acggtcgggt agcggaggag gggcggcagg gcacacctcc acaagtggtg ccgtcggttc
     3541 acctgatgta catggcctac gcacagtcag tcacgacttg gggggtacgt caacaccatg
     3601 gaggggaaac cgatttgggc catcgcagca cgtcaacgcg gtgtcatgct caggccaaag
     3661 ctaagccggt gctcagtcga cggcgagccg gaacgacatc cgcccgaagc cgacctgatc
     3721 gccctcgcgc acgaccgcgg cgccgatgac ccgccgcccg ttgaccgtcg tgccgttggt
     3781 cgagccgagg tcgcgcagca cccacatgcc gccctggcgg gtcagttcgg cgtgggtgcg
     3841 ggacaccgtt tcatgcgtga gacgcaggcc gttggccgga tcgcgtccaa tgcgcagcgg
     3901 gtgcccgttg ccggggtgcg gcagcagcag cttgggcagg cgctcggcct gccacgccct
     3961 gcgcagccgt acggtgaagc cggacaccgc ctccacggtg ccgaacacca cgcgcgagag
     4021 gcggctctcc tgggggagat cggcggtgag cacggcgagt tcgtccgggc ggcgggcggc
     4081 gagcgccagc tccatgcggt ggatgaacgt gtcgtgcgag agccgtccca tggcgacgcc
     4141 gtcgcgcagc accttcagcg ccttgtcgcg ctccgcgtcg gacagccgcg cggggtacgt
     4201 gttgaactcg aaggacgacg tcacgttcgt gattgtcggt cagcgggcac cgggtgtcca
     4261 gaaaacggga gaacgcccgc cacgcgcgcg tgcccccggc gacaccagcc gcaaaacggg
     4321 tgaatcaaaa gcgcattgat cccttttgaa gcaccatgga cgggctacat cacggtgaac
     4381 agacgaaggg gaaccgtccg tgcagttcga ggtgtgggca ccacaggccg gccgtgtgac
     4441 gctccggtgc gacggcgcca cgcgcgcgtt ggagcgcgat ccgcagcggg aggggtggtg
     4501 gcgtgcggat gccgaggcgc acgacggctc gcggtacggg ttcgcgctgg acgacggtcc
     4561 cgtgctgccc gacccccgtt cgcgccgcca gccggacggc cccgacgggt tgagcgcggt
     4621 cgtcgaccac gggcggtacg cgtggcgcac cgagtgggcc gggcgtccgc tgcccggcgc
     4681 ggtgctctac gagctccatg tgggcacgta cacccgcgag ggcaccctgg acgcggccgc
     4741 cgagcggctc gggcatctcg tcgaactggg tgtcacccac gtcgagttga tgccgctgtg
     4801 ccccttcccg gggcggcacg gatggggcta cgagggcgta tcgctgtggg cggtgcacga
     4861 gccgtacggc ggcccggagg cgctgaaacg gttcgtcgac cgggcgcacg agctcggcct
     4921 gggcgtcgtc ctggacgtgg tgcacaacca cctcggcccc tcgggcaacc acctccccgc
     4981 gttcggcccg tacttcaccg acacccatca cacgccctgg ggctccgccg tcaacctgga
     5041 cgctcccggc tcggacgagg tgcgcgccta tctgctcggc agcgcactgg cctggctgcg
     5101 cgactaccgc atcgacgggc tgcgcctgga cgcggtgcac gccctggcgg acacgcgcgc
     5161 gtacacgttc ctggaggagc tgtcgacggc cgtggacgcc ctgggggtgg agctgggccg
     5221 gccgctgttc ctgatcgccg agtcggacct gaacgacccc cggctgatca ccgcccgcga
     5281 ggagggcggc ctcggtctgc acgcgcagtg gaacgacgac ttccaccacg ccctgcacac
     5341 cgccctgacc ggcgagtccc agggctacta cggagacttc gcccgcgctc ccctcgccgc
     5401 ggtcgccaga acgctcaccg gcggctactt ccacgacggc acctactcga ccttccgcgg
     5461 ccggcaccac ggacgccctc tcgaccgcac gcgcgtgggc gcgcaccggc tcctcggcta
     5521 cagccagacg cacgaccagg tgggcaaccg ggcgctcggc gaccggctcg cggcgacgct
     5581 ctccccgggc ctcgtggcct gcgcggcgac gctgacgctg acggcgccct tcacgccgat
     5641 gctgttcatg ggcgaggagt gggcggccgg cacgccctgg cagttcttca ccgaccacac
     5701 cgatccggag ctggccgagg ccgtacggcg gggcaggcga cgggagttcg cggcgcacgg
     5761 ctgggcggag gaggacgtac ccgatccgca ggacccggcg acccgcgacc ggtcctgcct
     5821 ggactggacg gagccggacc gcgagcccca cgcgcgcgtg ctggactggt accgcgcgct
     5881 gatcgcactg cgccacgccc aggccgacct gaccgacccc gacctcgccg acaccaaggt
     5941 ggcccacgac gaacaccaac gctggctcgc cttccgccgc ggggacgtcc gggtcgccgt
     6001 gaacctctcc aaggaaccgg ccgcgattcc cctcggccct cgccacgcgc gcgtactcgc
     6061 cgcctgggag ccggtcgagg caccgggcgc ggacggggtg ctgcatctgc ccggggagtc
     6121 gtgcgtggtg ctgctgcaga gctgagggac ccacggccgt acgggacctc gccgtgccgg
     6181 agtcggcgag gtggctcaga tgtccgcgtc cccgccccgg aggtccgtca cacgctccag
     6241 gaggatcgcc tcccaggccc gccgcaggcg cagcctgagc aggggcaggg cgtcggtgtc
     6301 gcgggactgg agggcctcgg cgaggcgggc ggcggcgtcg cagcgggcca gccagaggcc
     6361 gcggaggcag gggcgggcgc cgtagccggc gagggtggcg gcgcggacgg ccgccggtga
     6421 gccgacggcc tgggccagtc ctgcgatgtc ctcggcgggg tcgcccacgg cggcgtcggt
     6481 ccagtcgagg acgccgcgca cccggccgtc ggcgctgacc accaggtgct cgcccctgag
     6541 gtcgtggtgg acgaggaccg ctgtgcaggg ctgggcggcg agctggacgg ccgccgcccc
     6601 ggtgagctgg tgcagccggg cggggtcgaa ctcgtcggcc gcgcccaggc gctcggcggc
     6661 gtgctgcgcg gcccggcgca gcgcctccag ggagcgcggg gcgacgcgcg ggacgccgag
     6721 cgtctcggcc tgccgggcgg gcacctcgcg cagcccgccg agcagccccg cgaggtcggc
     6781 ctcgccgacg gcggacacgt cgtggtcctc gcccgtaccg cccggcacct tcgtgtcgag
     6841 cgtgtacggc agcccgggcg cccactcccc ctgcgccaca ctggtcggca cggccaccgg
     6901 cagatacggg cgcaggacgt cacgcaggcg cagctcgcgg cgctgccgca gggccgcctc
     6961 gcggtccggg gccaggcgca gcacatggcg cccgccgacc caccaggtgg agtgcccggc
     7021 gccctcggcg acgggccgca cctccggtcc cgcggcgccg cccccgccgt ccttgagcag
     7081 ggaactgacc agcctgcgga cggtgtccgc ggtgggtgtc ggtgcctggg tcatggtccg
     7141 cgccgttgtc gctcgggggt gtggtggggc tcctggtggt cgttcagtcc actatgacca
     7201 tctcgcgggt cgtgtcgttc agccggcgcc cgccgtcctc ggtgacggtg acgatgtcct
     7261 cgatgcgcac tccgaagcgg ccgggcagat agacgccggg ttccaccgag aagcacatgc
     7321 cgggcatcag gggctgccgc tcgccctcga tcatgtacgg cggctcgtgc gtggtgacgc
     7381 cgatgccgtg accggtgcgg tggatgaagt actccccgta cccggcctcc gcgatcaccg
     7441 cgcgtgccgc ccggtccacc tcctggcagg cggcgccggg ccgcaccgcc cggaagcccg
     7501 cctcctgggc ctcgcgcacc aggtcgtgca cccggcgctc ctcctcggtg ggctcgccga
     7561 cgtggacggt gcgggaggtg tcggagccgt agccgtcccg caggccgccg aagtcgagga
     7621 cgaccatgtc gccgaactcg atgacgcggt cgccgacctc gtggtgcgga ttggcgccgt
     7681 tcggcccgga cgcgacgatg gtgaagtcga cctgggagtg gccgaactgc cgcagcagat
     7741 cggcgagatc ggcgccgacc tcggactccc tgcggcccgc gaagggaacc ttgcggatct
     7801 cctcgaacgc ctggtccgcg gccgcgcccg cggcggccat cagctccagc tccgccgcgt
     7861 ccttgacggc gcgcagcatc ggcaggacct cggtcaggga gtcgtaggag gtgccgggca
     7921 gcgaccgctg cagcccgagc agatgcatcg cccaggcgtt gtcgctgatg ccgaagcggc
     7981 cggcgccgga cagcagcgcg gcggtcgcgg cgtaggggtc cttgccgtcg gtccagtcgc
     8041 gcaggttcag ggcgggtgcg ccgggggcct gcgcggcgtc gggggcctcc agcgtgggga
     8101 cgaccaggac gggggcccgt ccctgggcga ggaccagcag ggtgaggcgt tcggtgaccg
     8161 cggtgggcgc gtagccggtc agccacacga ggtccggtcc cggcgccacc aggagcccgt
     8221 cgagaccggc gtcggcggcg gcccgcgcgg cgcggtccat acgggaccgg tagtcgtcgg
     8281 cggtgaaggg cacgcgcgtg ctgccggtca tccgagcctc cagggacgga tcagggaacg
     8341 acaagggact acgggcagca tcctgcccgg acagcggggg ccgcgcgacc ggtctgcggg
     8401 tctttcgcgc actgcgccgg acatgtcacc cgccgcgccg ggcaggtcag gggccgcgcc
     8461 gcgcatcccg tcagctctcc agggcgaggc gcacgccgag gagcagcagc acgccaccgg
     8521 agacctgctc caggcgccgg cgcaccccgg cgcgggacag gacggcccgc atccggccca
     8581 cgaaccacac gtacaggccg tagtagccga cctcgtagac cgcccagagc gcggacagtc
     8641 cgaccatcgt cgcgaggtgc ggggcgccct cgggcacgaa ctgcggcagg aaggacatgg
     8701 cgaagatcgc cgccttgggg ttggcgaggt tcatcagcag cccgccgcgg taggtcgccc
     8761 agccgctctt ccgcgtgccc tcccacgccg tgtcctcggg cgcgcccccg gcgcggcgtg
     8821 cctgccgcag tgcctggatg ccgaagccga ccaggacgac cgcgccgacg atccgcatca
     8881 cgtcgtaggc cacctcggag gccgcgagca gcgcggtcag gccgaaggcg gctacgacgc
     8941 cccaggtgaa gacgccggtc tcgttgccga ggaccgtcag gaacccggag cgtctgctgc
     9001 gcagcgactg cttgatgatc agcacggtgc tggggccggg cgaggccgcg atgagggtgc
     9061 aggcgccgag gaaggcgagg agggtgctca tcatgagggc catcgttgct cgcgtcgccc
     9121 gctctggcca ccgcttttcc cgggcgcccc acgacgtctc cccactcccg tcgccacgcc
     9181 cctcacgacg ccgctcgcgc tcccggcggg cgtgccgcgg cgcgtacccg gccggtcctc
     9241 acatgacgaa ccccgggacc accgccaact gctggtatcc gccactgtga tgacgaaccg
     9301 tcacggtgac gccggtgccg gggcgggcgt gcgcgacggc gcgggcgagg tcggcggccg
     9361 tgtcgacgcg gctcccgccg aaggtgagaa gtacgtcacc gcggaccagg cccgccgagt
     9421 agccggggcc ggggacgtgg acggcgacga tcagggctcc cgccttctgc gcgtcgacgg
     9481 cctccaggcc cagggtcgcg gcggcgggtg cgggggacgc gggcggggcc ggggtcgcgg
     9541 tggggacggc ggcgccggtg tgcggcagcg cgggtggccg ctgcggtgcc tggcgctgca
     9601 ggtcggcgag cttgctcata ccgatcacgg tggcgcccac ggtgccgatg cccaccccgg
     9661 acagcaccag gaccaccgcg acgaacaggc cgaacaacag ggcccgcagc cgccgtgccc
     9721 gcctgcgtgc ggcgtgcgga cgccggacgg gaacgccgga tcgggtgcca cggccgggat
     9781 cctggcccgg catcggcttg ggacgcaacg cagtctgttc catcgatcgc ctccgctgga
     9841 gcactacccg gcgctccggc gcacgacgag ccacgaacga gtgagactga cctgcggtca
     9901 gcggtggcag gcggggcggt gaacccgcgg ccgccgcccg cggcacggag cccgcgacag
     9961 ggagtcgggc gagcggcaga ccggcgtcag gatcgggccg ctacaggaca ggcacggcag
    10021 gcgggcggcc cgggacgaag ccgtgggcgc ggcgagcgag gtagccggcc ttgtagcggt
    10081 ccaccgagcg gtgccagtgg aggatgcccg ccatccagtg ctgcaggtcc cgcacatagc
    10141 cgtccacggc cgcgcgctcc tgctcggaga ggccgaagtc ctgctggacg acgggcagtt
    10201 catgtgcggc gacatgctgg aactggcgca tgcgctgggt catcaggtcg tggacgacac
    10261 cgagcgcggt cgggtagtcg acgccgaaga agttctgcac gacgaggatc gcgttgtgga
    10321 tctccccctc gtactcgatc tccttctggt acgagaagac gtcgttgacg aggcaggcgt
    10381 agtcgatggc cgcgttctcc agcgagcgga ccgggccgct gcggtagacc tcgggcgcga
    10441 tggccgggcc gtaccccatg cggcacatgc tcagggtgag gtcggagccg aaggtggcgc
    10501 ggcgcatctc cagatagtcg accgggtcgg ggatgcggtg ctgcagttgg ttcgacagct
    10561 cccacaccca gctctcggtc atcgcgttca ccgcgtcctt gagggtgcgc cgttcgtccg
    10621 gggtcatccc ggccgtcgtg cgcgcccaca ggtcggtgag gccgcgctcc atgccgttca
    10681 ccgggacgac ggccacctcg ccgtccaggg gcatgcagtc ggcgaggcgc cgggtggtca
    10741 ggcgggccgc ggccaggtcg cggcggttgc cgtacacgag cgggtagtag tcgtcggcgt
    10801 acgtccccca ggcgagccac cgggagctga ggtccagggc ctcgggcgtc gcgtccggat
    10861 cgatgcccgc ggagcacagc gggaggtcgc aggcggcgag tttgtcctcg tcccagacgc
    10921 cctcctccag catgcccatg gcgtgcatcc aggcggtgag ccggggccgg gccgcgtcca
    10981 gatgcgggct cacctcgacc tggaagggca tgtcgaagtc gggcagcagg gacggcccga
    11041 cccgttggta cggcgtatgc gtgtacgcgc gcaggcgctc ggcgccggcc gcggcgagca
    11101 gggcgccgat gtcggcggac gagccggggc cgggcgggcc gtgccacgga ttcgccgact
    11161 gcgcgcgggc gttcatgtag cggctggagc gcagatgcca ctcgtggccg ccggactgcc
    11221 agtcctgcag tccctgggtg tacttggcga cggccgcgac ctcgggcggg gtcagacccc
    11281 tctccagggc cagcgcgggc acttcggtca gggcggtgtg ctcgaactgg tgcaggcgcg
    11341 aggtgaggat gtcgttgacg gtgtcggcgg cctcctgggt ggtgcagccg aagaaggtct
    11401 ccaggacgag cacgccgttg ctgttctcgc cctcgtcctc gacctcgcgc tggtaggaga
    11461 agaggtcgtt gcgcaggtgg acggcgtcgg cgaacgtctc catgagcacc ctcagcggcc
    11521 gcgagccggc gaccgcggcg gggacctcgg ccgtcgcgta ctccacgagc cccgccgacc
    11581 agggggcgcc gcccaccttg cggcgcatct cgatgtactc gacggggttg gcgatgcgcc
    11641 cctcgttgat gttggacagc tcccacaggg actcgttgag caggtgctcg gtggccacgg
    11701 cgaaacggcg gcgccagtcg gcggacatgg cgggcacggt gcgcgtccac aggtccgcga
    11761 gtccggcctc caccgggttc tgcggctcgg gcatcggggt gtcggggccc atcggcatga
    11821 acagtgggag ccggtcgaga tgggccttgc cgccggcgcg gtcctgggtg cgtttgaaga
    11881 tctccaggaa gtggtcgtcg aagaagaaga cccacacgta ccagtcggtg atcagggaca
    11941 gggccgggcc gtcgcactcg gggtgggtgt acgcacagag cagtccgtag tcgtgagcct
    12001 ccaggtcgga ctgctcccag atccccgacc cctccaacat gcccatcgcg tgcgcccact
    12061 cggtcgaatg ggcccgtgcc tgttcgacgt gagggttcag ccgcgcggga tacggcatgt
    12121 agaagtgcgg gagttcgaac ggctgttgcg tcatggccgg gccctacccg tggcccgtcg
    12181 gcaccatcct ccggcccgga catgatcaca ccatcgcgtg aatcaggggt ggattcggga
    12241 gttctcccgg gcccttgtga cgttcacctc tacgcgcgca gactaccgaa gttcacgtct
    12301 cctccctcac cggagtcccg atggaccacc agcccagaac cctctcccgc cgcaccgccc
    12361 tcgcctcgct cgccggggcc gcactggccg gcaccgccgc cgtgcccgcc gcggcgtccg
    12421 gcctcgcccg cagcgcccag ggcgcgggag gcacccacgg cggccgcacc gtgcgcttcg
    12481 cgaccttcaa cgcgtcgctc aaccgaggca cccaaggcgc cctggtcacc gacctgtcca
    12541 ccccgcacaa cgcccaggcg cggaacgtcg cggagacgat ccagcgcgtg gacccggacg
    12601 tcctgctgat caacgagttc gactacgacg agcacggcac ggcaatctcc ctgttcctgc
    12661 gcaactacct cgccgtgagc cacaacggct cccggccgct gcacttcccg caccacttca
    12721 ccggcccggt gaacacgggc gtggcctccg gtgtcgactt cgacggcaag aacggcgcgg
    12781 tgacgacgcc cggttcggac gcctacggcc aggacgcctt cggatacggc ttcttccccg
    12841 ggcagtacgg catggtcgtg ctgtccaggt tcccgatcga cacgcgcgcg gtgcgcacct
    12901 tccggcactt cctgtggaag gacatgccgg gcaacgtgat gccgccgggg tactacagcg
    12961 acgaggcacg cgcgatcttc cggctgtcct ccaagagcca ctgggacgtg ccgctgcgca
    13021 tcggccgcga caccgtgcac ttcctggtgt cgcacccgac gccgccctcc ttcgacggcc
    13081 ccgaggaccg caacggccgg cgcaaccacg acgagatccg gctctgggcc gactacatcg
    13141 gcgggcgccg ccgcagcgcc tacctctacg acgacaaggg cgtgcgcggc gggctgcggc
    13201 ccggagcgcg gttcgtgatc gcgggcgacc tgaacgcgga cccgctcgac ggcgacagct
    13261 acgaccacgc cgtactgcag ctcctcgacc atcccgcggt gcgccgccct gccaccccgc
    13321 cggcgagcgc gggcgcggtg gaggcggccc ggctgcaggg cggcgccaac acctcgcaga
    13381 ccggcaaccc ggcgtacgac acgggggact tcgccgacac cgcgccgggg aatctgcggg
    13441 tcgaccacat ccttccgtcg aaggggctga cgcctggggc gaacggcgtg ttctggccca
    13501 cgtccgacga cccgctgtac cgcctcgccg gcgacggcac cacggtcgtg acctcggacc
    13561 accggatggt gtggcaggag atacgggtgg actgaccgga cgtctgtggc agtactgcca
    13621 agtaggggtg aaggcacggc tgttcaggtg gcgcggggcg atccgtgggg cctaggctcg
    13681 atcgccacat ggaagccgac cggccgttcg cggcccgggg gaggtaggcc gtcatgaccg
    13741 aggcaccgct gcgcgcggag ctgctgctca cccacgacgt ctccgcggag ctggagcggg
    13801 aactgaccgc cgggttccgg gaactgggtg cgcccgcggt ccgtgtccgg cgcacgctcg
    13861 atcaccgcgg cccggccgaa ctgcagtggc tggcgctcgt gtcactgcct ctgcaggcct
    13921 tcctcagcgg gctcggcggg gaggccgtca aggacggcta ccgcgcgctc agggatctcg
    13981 tggcccgcct gttccggcgc gggacgaccg cgccggacgc ggcgccccgg ccgctggtgc
    14041 tgcaggacga gcggaccggt ctgcggatcg tcctggaggc ggacctgccg cagcacgcgt
    14101 acgagcagct cacggcgctc gatctgagcg ggttcaccgt cggccccctg cactacgacc
    14161 tcgcgcgcgg caggtggcgc tccgaactgg acgaggcggc gggctgaggc gcggcggcga
    14221 agtggcgtac gacgacgtgc accacgaacc ggacgcgcgg ccccgccccg aggacgcgag
    14281 ggcaaggcgc cccgccgccc cgccgaaccg gattctgcgc aactgcgagc ggggggaggc
    14341 ttttctggcc gcgggggacc tgacggctgc ggcacgggcg ttccgtgcgg tactggccga
    14401 ggtgggtccg ctggaggacg gcagtccgga gggggacggc gggtgcgcgg cacccacgac
    14461 gggcgccggt accgactcgg cgggcggctc ggccaccgcc cggggcgcgg atgccgattc
    14521 atcgcccgcc ccggacgcga acgcggaaac gccttgcggc tccgactcgg acgccgacag
    14581 gaccgccgtg ccggacgccg acgccgactc gaccgccgtg ccggacacgg acgccggcac
    14641 cgacgcagac acggctgcag gcgcggacgc ggacacggca acaggcgcgg acacagacgc
    14701 ccacgcgacc gctcaaagcc ccacccccac ccccgcccac ctcgcctccc gagcccacat
    14761 cggcctgggc cgggtggcgc tccggatgga gggagcggac cgggccgaga gggagtttcg
    14821 gcgggcggcg cggttgcggc cggggagtcg ggagccgttg tactggctgg gttgcgccgc
    14881 cgcgcaccgg ggagcgcagg accgggacgc ctacgagctg gccgagttga ggttcacgga
    14941 ggtggtggag cagtggcccg gtgacggagc gagcctggtg cagcgggccc acgtccgcgt
    15001 acggctcggc cgacccgccg acgcactcgc cgacttacgc tccgcggagc gcatcgcccc
    15061 gctggacgcg gaggcccgct gggtgctggc cgccctctcg ggcgccacgg caccggaggt
    15121 cgcccggcgc ctcggcacgg cggcgcggtc cgccatggag cgcgccgccg ccaccgggcc
    15181 gaagggccgc ccgcgcgcgg ccgacgactg gaaccgggcc gtgactttgc tcgaccgggc
    15241 ccgccaactc gaccccggca accgcgagtt cgcccttccg cacgcggtcg ccctctgcct
    15301 gagcggccgt cgcgaggacg gcatcgcggt gatcgccgac gcggcacgct ccgcacccac
    15361 cgaccggcat ctcgcgcaca ccctcgccgt gatgtcctgg cacgcgctcg cacccggcga
    15421 cggcactgac accgacgcag ccacagccgc agccgccgat accggcaccg acccagacac
    15481 agaaacagac ccagacccag acccagaccc agacacagac acagacacag acaccgtgga
    15541 cgacgccggc gaggacgtac cccgtacctg gtcccgatgc gtcgcctcct gggccgggct
    15601 cctgcacgac acccccttct gggagcggct gcgcgccggt gcggccgagc ggtacggcgt
    15661 ggtcgtcgac gacaagaacc tcgccacgct ccgcgccgac ctccaggccg cgctggaagc
    15721 tctcatgccc gagacgggcg ccggtgaccg gatctccccc gaggcgctgc tgcaccgcga
    15781 gaccgaggcg gcgcggctgc tcgcagaggc cggtgggctg ccgttggcga ccggttccgc
    15841 gcccttggtg tgcggtccgc tgcggatcgt ggagttgggc agggaggcgg agttgggggc
    15901 gttcgtctcc gcggcgggcg acgccgcacc ggcgctccgc caggccttct cccacctcgg
    15961 tttcgcgcag gccctgctcc gcctcgaccg tcccgcggag gcgctctccg cgctgtcggg
    16021 actgcgctgc ccgaggtgcc gcgcccgcgg cggcagcggg gacgagggca ggcgaggcgg
    16081 tggtggagag cagtcgggcg gggatacggc gtcccatggg cgggcggccg cgcctcgcgc
    16141 ggagcgtggt gccgtctgcg atcccgactg cacccgcttc gacacccgta accccgccta
    16201 cgccggacag gctgccaaac acgtcctgct gatgcgggac gggcgctcgc tcgcgttggc
    16261 cgcacgcctc gcccagggcc gcgccgcgct gacgcccacc gggcccgatg tccgcagagc
    16321 cgcgacgagt tggcagcgcg cgctcactca cgcccgggcc atcggacagg gcccggaggt
    16381 cgaggcgatc gtggccgaca cggcgctcgc cgcggccaag gcgctgcacc gggccggtga
    16441 catcgacgcc gcgggctcga ccctggagtc ggcgtacgcc ctgctcggcg agggccagca
    16501 cgagcgtctg aaggggcagt tggcgcgggt cctgaccgac cgcggcatcg cacaggccaa
    16561 ccgtgacatg gaccggctgg agggcccggc cgccgatctg cgccgcgcgg tcgagatcaa
    16621 cccccatctg caccgggccc aggccaatct gggggtcgtc ctgcgcatcc tcggggcacg
    16681 catgcggtgg tcgggaagcc tggtggggtg caggagcagg ctgcaggagg cgctggaccg
    16741 ggtcacggcg gcactggagc actttcccgg ggatcctgag ctctctcagc tccgagatct
    16801 ggtggaggcc gatctcgccc tggttcactc ggagttggag caggggcgga tcgggggact
    16861 gccgtagtga tggaatacga ggagctgcgc ttccgggtgc gccaggtcgg cgcgcaccgg
    16921 catgtactga cggtgagcgg tgcgggaggc gccgctgacg tactgacggt gggggccagg
    16981 cccgaggcct atcgcgagcg cctggagcag ctgatcgagg ccgagctcgg gtacgcgccg
    17041 ctcggcgacc aggatcccgc cgcccggctg cgtgacctgg gccgggacgt cttcgcactg
    17101 ctgctgggcc gacgggcggc cgagtgtctg cgcgcggcgc acgagcgggt gcggcgcatg
    17161 cagcccgcgc gcgggctgcg gctgcgcttc gacctgccgc cgggtctgcg ctcgctgccg
    17221 ctggaggcgc tgtgcgcgcc cgccgccgaa ccgggccagg cgcccgcgtt gcacgacagc
    17281 ctgtcgctgg tgcggtcact gccgggcgga ccgatcggca gacggctgcc cgacccggag
    17341 gacgccccga gcaggatccg gctgctggtc gtgcacgcct cgcccgaagg cgcgcagctt
    17401 ccggtcggcg aggacgaagt cgcgtcgctg ctgcgggagt tgccgcaggt cgccgtcgag
    17461 acgacgctcg tacggccggc cacccgcgag cggctggagg ccgcgctggg cgagcgctcg
    17521 gacctgccca cagccgtcct gctgatcgcc cacggtacgt acgacaccga gcgcggcagg
    17581 ggcacggtgc acctcgagac ggtggacggg cgcaccgacc aggtgcccgc cgatttgctc
    17641 agcggcatgt tgctgcaggc accccggctg cgcctcgcgg tgctcaacct ctgttcgggg
    17701 gcggacagtt cgcacaccga gccgttctcg gggctcgccc aggcgctgat cgacggcggg
    17761 gtgcccgcgg tggtggccat gcacggccgg gtcagcgacc gttcggcggg tctgttcggg
    17821 cccgcgctgc tgaagaagat cgcggccaac cggacgatcg acgaggcgat ggcctacgcc
    17881 cgccgcacca tctcctacca gtccgggcac acggccaccg agtgggcgac cccggcgctg
    17941 ttcctgcacg aggagtgccg gcacggctgg ctgttcaagg cgcgcggggt gcgcgacggc
    18001 ggccacgcgg cgcacgatcc gctgcgccgg ggcgccgagg cgctggatgc ctacaacaac
    18061 cccatcgggg acgtggattc ggcccagctg atcgaagcgg cccgcttcca gcggctgcgc
    18121 agggactggg agcaggtgcg cagcatcctc gccaccgatg tgcagcggtt ccgccgggag
    18181 caggagctgc ttcgcgagga ggccgcgtac gagctggcct gggagaaggt gcagggcctg
    18241 tgcgagctgc tggccgcgga ggacgcgacg gcggcgcaca gggcgctgcc cggggtgcgg
    18301 ggcgcgctgc cgcacggcga acaggcctgg ctgcccctcc tggacaagga ggtgcaggac
    18361 ctcacccggc tcaccgcgct gctggagcag gcgcacgcgg ccgcgcggga ggcggactgg
    18421 gccggtgcgc tcgcgctgtg cgcggagatc ctcgccgagc ggcccgccgg gttcggtgac
    18481 gcgcagcggc tgcgcgacac cgccgtggag gagcaggcgt tgcaggaggc ctgcgccgaa
    18541 gcgtcggcgg cctgcgccac gggcgactgg gcggccgctg ccgccgcctg ggaccgggcg
    18601 ctcgcgctcc gcgccgacca cggccctgcc ctggccggac gggcgtatgt gcacggccgc
    18661 acggccgagg agagcgggga ctggaccgcc gccgcggacg cctacgcgcg ctgcccgcag
    18721 ctgcccgacg cgacggcccg cgcggcttac gcccggggcc gtcaggccgc ctcggccggg
    18781 gactggagcg cggcccacga cgcgttcgag gaggcggcgg cccggggcgc cgagaacggc
    18841 ggggcggcct tggacgtaca ggccggggca ccgaacggca gctccaacgg acacgcacgg
    18901 actcggcccc actcccccgc actcacctcc tggctcgcct acgccgccgc gcgcgtcgcg
    18961 gaggaacagg aacggtggga ggaggcggcc gaggcgttca cgacggccga cggtttcatc
    19021 gacgccgccc ttcgagccca ccacgccagg ggccgcgcgg ccatcaagaa cggcgcctgg
    19081 cccgaggcac tggaggcgat gcagacggcg gcggggctgc gcgcggaggc cgaaggggtt
    19141 ctgccggcgg cggctgcact gtgcgcagag gccggggccc tgcccgcagc ggccggactg
    19201 accgcggagt ccgaaggaac cctaacgccg gcggccggac tgaccgcggg ggccgaagga
    19261 accctgccct cggcggccga actgcgcgct gaggccgaag gggccccgcc cacggctgct
    19321 ggggtgcccg cggaagccga agcgaccccg cccatggcgg cccggctgcc cgcagaagcc
    19381 gaaggaaccc cgccctcggt ggcaggcgtg cccgcaggag acgaagagac ctcgcccccg
    19441 gcaacccggc tgcccgcaga gcccggtaga gccctaccag ccgcacaccg tcccccggcg
    19501 ggcagcgcgg tggccgccgg caaggcgccc cacgccggcg cgcaccctca agtcggcgac
    19561 agcccagtcc tgttggccga cccgctcccc gaccccgcct cctggatccc cgagttgtgg
    19621 gagcgggtgc gggaatgggc cggggttgtg gcggagtcgg gggactgggg gcgggcgctg
    19681 gagtgttggg ggatgctgcc ggacgggttc gaggacacct tgccgcagcg tcggttcgcc
    19741 gaggggcggg tggcggaggc ggccggggag tgggaggcgg cggccggggc gtatgccgag
    19801 gcgttgcacc ccgacgcttc cgcccggcgg cactacgccc tggggcgggc ctcggcgctg
    19861 tgtgaggagt gggacgcggc ccgcgaacac ttcgccgaag tccccgaccg tatccatgac
    19921 ttcccggagc cgcccgcgcc gctgcggctg tacgcgcaag gaagggccgc ctccgcgcgc
    19981 ggcgactgga aggcggtcgt ggaggacttc ggcgggctgc cggacagcca tgccgacggc
    20041 gacgtggggc atcggcggcg gtacgcacgc gcgcggatcg ccgagcagca ggaggaggtc
    20101 agggccgaca cctggatctc ggtgctccgg cacctggacg acgtaccgga cgctgccctg
    20161 gacggggcgg tcggtctgct gcgccgcaaa gcggccgggc tgcacgcgct ggggcaggcc
    20221 caactggagc gtgcccggga cctgttcgag ccgttcgccg ccgaggacga ggagttcgcg
    20281 ctgtggcacg gatacgtgct ggcgcggctg cacgagcgcg acgaggcctg ggaggaggcg
    20341 ctggccgcct accgcgccct gcccgcaggc cacgccgacg tggcgccccg cacccggtac
    20401 gccgaggcgc gggtggcgga ggcggtcgcc gaaggcgccg agcagtgggg tgccgtgcgg
    20461 gaggcgtacg cggagctggc ggacgccttc gccgaggacg gcggtttcgc cgacgcggcg
    20521 gtgcgcgccc agtacgcgcg ggcccggctc gccgaggccg agagcgactg ggaggaggcg
    20581 tgccgcagcg ccgacgcact ccgcgcgcac gccgacgcgc cgctgatcgc cgcctatgcg
    20641 cggggccggc tgaccgaggc ccggcgggac tggcaccggg ccgtggacgc cttccgggcg
    20701 agcgggtcct accgcgacgc cggggcgcgg ctcgcccacg ccgaggggcg gctgctggag
    20761 gagcagggcc ggttcgcggc ggccgccgag gcctacgagc gggccggtga cgggcacgag
    20821 ggggcgcggg cgcaggcagt gcggctgcgc ggcgtgctgc ggctggcctg ggtggacggc
    20881 gccatcggcg agccgctggt ggcggacccg ttcgcgctgc gggaccggac gttcccgtat
    20941 ctggcgctgc gcgacgcggg cgtaggcccg ggctcgtcga tggatgcggt gaacgaggtg
    21001 tcgttcacgc tgatggagcg cgaggagatg agctggtcct ggccggagcg ggtggcctgg
    21061 gaccggctgc gggtggccgc gcggcggctg gagctggacg cgcagctcta ccggtggcac
    21121 gccccggccg cggtccgtga ggcggtcgcg catctcgcgc cggacgacgg gcccgatccc
    21181 ctgcaggcgc tgtgcgagcg gttcccgaag gacgccccgc tgctgctact gctcgcccgg
    21241 ggccgggacg cggccgtggc ggcctgggag gagcggctgg cgacggcccc cggtgacatg
    21301 gcggtggtgc acggtctggc cgtggcccgg ctgtggcagg cgcgggaact ggaacacagc
    21361 ggcgcctggg agcacgcggt gcgcgcctgg gaggaggccc tcgcgtactg ggccgcgctg
    21421 ctgagcgacg agggctactg ggacggctgg cgcaccgaac gcgcggcctg ctaccagcgg
    21481 accgtgtcgc tcgacgacct gacgagactg cgccgggatc tgagcctgca tctgtccgac
    21541 gggctggccg cgggcgagga gacccacacc gaccagggcc ggcccgaaca ggccgcggag
    21601 taccggcggt tgacggcgct gttcgaggcg gagctcggcg gggcgagggt gctgaaggag
    21661 gtcggcgggc tgccgacggt gccgggcacg gccctcgcgc tcgcctgcgg gccccggtat
    21721 ctgcacatgc tgcgtctgga ggtgccgctg gccgagcggg tggccgagct gagcgcggcc
    21781 gcccaacagg gccacgatcc gggcgagttc gccgtacgaa agctgcgctg ggcgttctcg
    21841 gagctgtccg gtgcctacgc gctcgctgag gcccaccggt tcgaggaggc catcgaggcg
    21901 atgcccgtgc tgcccgcgct gaccgagctt cccgacgact gcgcagaccg ggacgcgaag
    21961 acccattcgc gcgactgcgg ccactgccag gacttcgtgc gccgcggccc ggcctatctg
    22021 cggctgccgc ggcggcacgc ccggttcgcg caggacggtg cggcgctcgc ggtgcacgcc
    22081 cggctctcgc tcgcccaggc ggcgctcacc agtggctccg gcgcgctgga ccgggcggtg
    22141 gagcactggc ggca
//
