LOCUS       NZ_CP034669            23222 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Corallococcus coralloides strain B035 chromosome, complete genome.
ACCESSION   NZ_CP034669
VERSION     NZ_CP034669.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus coralloides
  ORGANISM  Corallococcus coralloides
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 9587888)
  AUTHORS   Bouhired,S.M., Rupp,O., Blom,J., Schaeberle,T.F., Kehraus,S.,
            Schiefer,A., Pfarr,K., Goesmann,A., Hoerauf,A. and Koenig,G.M.
  TITLE     Complete Genome Sequence of the Corallopyronin A producing
            Myxobacterium Corallococcus coralloides B035
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9587888)
  AUTHORS   Bouhired,S.M., Rupp,O., Blom,J., Schaeberle,T.F., Kehraus,S.,
            Schiefer,A., Pfarr,K., Goesmann,A., Hoerauf,A. and Koenig,G.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2018) Institute for Pharmaceutical Biology,
            University of Bonn, Nussallee 6, Bonn, NRW 53123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-SEP-2017
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 350.5x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004104415.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:23:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,767
            CDSs (total)                      :: 7,695
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 30 of 79
            Pseudo Genes (incomplete)         :: 55 of 79
            Pseudo Genes (internal stop)      :: 4 of 79
            Pseudo Genes (multiple problems)  :: 10 of 79
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:35:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7152897
            Orig. end                         :: 7176119
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034669.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Gabriele M. Koenig,
            Institute for Pharmaceutical Biology, University of Bonn.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23222
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="33"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23222
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23222
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13222](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13222
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(730..1575)
                     /locus_tag="EJ065_RS28520"
                     /old_locus_tag="EJ065_5664"
     CDS             complement(730..1575)
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-253). E-value:
                     1.6e-34. Score: 111.6. Matches aSDomain:
                     nrpspksdomains_EJ065_RS28520_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="EJ065_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5664"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_128798618.1"
                     /sec_met_domain="PF00561 (E-value: 9.8e-26, bitscore: 89.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-17, bitscore:
                     64.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLKVPGGEMAWHEEGQGTPVVLVHGTPSSSREWRDVARRLSPS
                     YRVLAPEHLGFGDSERPGDWRTYSLPWHVENLRAWFDQLALGPFHLVVHDFGGPIALPL
                     AIAAPERVLSLTVVQSWLWDLKGPNVDNALMRWLYLSWNFSARTLVKMSWGRRTKLTRE
                     LHQSFLSRFPDRASRMGTWGFARSISHEGPWMDEQGQGLGRLADVPSLVVWGRADKLVK
                     PEHLSRWKQALPRARVLELEDVGHFPQLEAPDAVGAALLEQLARVGQPRSIDSLSPAPV
                     "
     aSDomain        complement(817..1515)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EJ065_RS28520_Abhydrolase_1.1"
                     /evalue="1.60E-34"
                     /label="EJ065_RS28520_Abhydrolase_1.1"
                     /locus_tag="EJ065_RS28520"
                     /protein_end="253"
                     /protein_start="20"
                     /score="111.6"
                     /tool="antismash"
                     /translation="PVVLVHGTPSSSREWRDVARRLSPSYRVLAPEHLGFGDSERPGDW
                     RTYSLPWHVENLRAWFDQLALGPFHLVVHDFGGPIALPLAIAAPERVLSLTVVQSWLWD
                     LKGPNVDNALMRWLYLSWNFSARTLVKMSWGRRTKLTRELHQSFLSRFPDRASRMGTWG
                     FARSISHEGPWMDEQGQGLGRLADVPSLVVWGRADKLVKPEHLSRWKQALPRARVLELE
                     DVGHFPQLEAP"
     gene            complement(1572..2180)
                     /locus_tag="EJ065_RS28525"
                     /old_locus_tag="EJ065_5665"
     CDS             complement(1572..2180)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="EJ065_RS28525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5665"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_164933336.1"
                     /transl_table=11
                     /translation="MPRTADANAVLREKTRERVLQAAVRLFSRHGFDGTSVRALAQEAD
                     IAVGLLYSHFASKEAVLSALMQSSMLDVARTLEAADLEPTARGFVTVLLTSAVEMMDAH
                     RDLWRLSQGLRHQPEVLARLKLPFEHFLGATHQRLKAALAARGVPEADIEARVLFALVE
                     GISQQYVQHEGGYPAAKVIRAAARRWPATPSRKRKADTP"
     misc_feature    2357..2372
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.86"
                     /tool="antismash"
     misc_feature    complement(2357..2372)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.47"
                     /tool="antismash"
     misc_feature    2363..2376
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.57"
                     /tool="antismash"
     misc_feature    2364..2377
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            2441..4435
                     /locus_tag="EJ065_RS28530"
                     /old_locus_tag="EJ065_5666"
     CDS             2441..4435
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398743.1"
                     /locus_tag="EJ065_RS28530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5666"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_128798620.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.7e-40, bitscore:
                     136.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKLTQAVSAISLLAAACGPMPEGPESDSEQIGQTAQMIRRERA
                     IPNEYIVVLRDSTQEVRQQGAANIARELVSLTSGRVLRTYEHSIHGFLANMTEAEARRL
                     LSDPRVAYVQENGLIHVSATQTNATWGIDRIDQRDLPRNSSYTYNVDGTGVHAYVIDTG
                     IRQTHTEFTGRIGNGYDFIDNDSDPSDCHGHGTHVSGTVGGTTWGVAKKVTLHGVRVLD
                     CTGYGNDAQVIGGIDWVAANHVKPAVANMSLGDVGIQAIDDATERLIAAGVTTVVAAGN
                     DSANACNYSPARTPNAITVGSTTSSDGRSSFSNYGTCVDIFAPGSSITSASNSGNSSST
                     SMSGTSMASPHVAGAAALYLGANPTAAPAQVRDALVNNATPNKVTSPGTGSPNKLLYTL
                     FITGGGGSDTTPPTTSITSPAGGATLSGTASLSASATDNVGVSRVEFYAGTTLLGTATA
                     SPYSLSWNTATVANGTYALTTKAYDAANNVGTSSTVSVTVNNGTGSCSITEQLFVNAGF
                     ESGNTGWTTSSGVIDGTTSGSAPRTGTYKAYMNGYGTTRTDFAYQDVTIPASACSATFT
                     FWARITSSETTTTTAYDKLAVQVRNSAGTVLATLATYSNLDKGTAYVQRTFNLAAYKGQ
                     TVRIYFNGTEDSSLATSFFIDDTALTVVR"
     misc_feature    complement(2442..2456)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.99"
                     /tool="antismash"
     misc_feature    4647..4662
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.27"
                     /tool="antismash"
     gene            4745..6886
                     /locus_tag="EJ065_RS28535"
                     /old_locus_tag="EJ065_5667"
     CDS             4745..6886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398756.1"
                     /locus_tag="EJ065_RS28535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5667"
                     /product="M28 family peptidase"
                     /protein_id="WP_128798621.1"
                     /transl_table=11
                     /translation="MPLRPLPFALLALFVSLGASAQAPRSPLGPISPTTGLVLRDDVVR
                     ALIQESSGDRIHDGVQRLSLIARDSVDGYAEAATWTKAAAEAAGLQDVQLEAMKDGPQW
                     RATHGELWVAGPHRYRVTSHADQPMSLAIGSGSFEGSDLELVDVDTGTQDAEYAGKDLK
                     GKVVLTRGLPSAALRNGVLKLGAVGVVSSYSTPPWNLPNRMDGDFPDQVGWAYVSRSLM
                     PQGARTPFVFMVSDRQARELRAQLREGPVKVDVSIATQAPTGHLSIVSGVIPGTRAGEE
                     VVLTAHLDHYKPGADDNASGAATLLELVRTYTTLIRRGVLPPPVRTLRVLWLPEFEGTR
                     EWFSHHGADPVRRVAQFNFDMLGASMTRVHSRFQVSYTPDWNGSFVNAVSESTVAFMNR
                     FNGVAYPPRKDFRIGSVTGSRDPMDAHMERYGRGSDHQLFNDHGIPGVAYSTWPDDGYH
                     TSGDRPENVDPTQLHRAAFAGLAGITVAAWAEGTGALELSRLVAVHGAKRVAEDEFRAR
                     RELAATPAAQVPGFARLARAGVRAGYQRERDALRSCLALGAPAEPVKAMVQALETAESQ
                     ALKRLDADGKARGVSLKEPSPGEAERKARAFVPRRVKGQELASFDELERNAPTASKARV
                     DAVKAAMTAAATALREQGESELRFYQLADALASYADGKRSVADIRDAAHAEYGYVFPVE
                     AMLDLFGLLEQGGIMTRGR"
     gene            7201..7899
                     /locus_tag="EJ065_RS28540"
                     /old_locus_tag="EJ065_5668"
     CDS             7201..7899
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS28540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EJ065_5668"
                     /product="hypothetical protein"
                     /protein_id="WP_240672482.1"
                     /transl_table=11
                     /translation="MDASTPDAGTEDAGAGDAGSLDGGGSTPEASLRITEINPDAPQDL
                     IELVAVTGGTLTGISLQELTNSDFAFTFPQGFTVETGAVLVLHLGGSCTDAPGDPASCG
                     QTAPFSASAWDFSMPGTLSYSGKVLELLSSKSVPVDGVPFVRASGEMPLSIVAAIQRLQ
                     ADRVWDATPCIHDMTTGFAKDRYCRNIAADWSGLNESSSIMRISGTTPLTTPGLKTQWS
                     GPLPSRWGSY"
     gene            complement(7919..8845)
                     /locus_tag="EJ065_RS28545"
                     /old_locus_tag="EJ065_5669"
     CDS             complement(7919..8845)
                     /EC_number="5.4.99.-"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1279: pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398758.1"
                     /locus_tag="EJ065_RS28545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5669"
                     /product="RluA family pseudouridine synthase"
                     /protein_id="WP_128798623.1"
                     /transl_table=11
                     /translation="MSQPDDSAGLNDGYVYRERIGAASVGRTSLAHLTGTYRHSTEEQW
                     RARFVRGEVRLDGLIATGDEVLQAHQELCWHRPPWRERETPDSFELVYEDASLLAVIKP
                     SGLPTLPSGGFLKNTLLSFVRLRWPEASALHRLGRATSGLVLFSRTQEAAAKLSGNWRE
                     GDVEKRYRALSDGVAAQAAYDIHTPIGLVPHPLLGSVHGASAKGKPSHSRAEVLERREG
                     QTLFEVRIHTGRPEQIRIHLASIGHPLTGDPMFASGGLPREHEPGLPGDGGYLLHAETL
                     AFTHPLTAERLRLHAPPPAGLKTASEA"
     gene            8910..9479
                     /locus_tag="EJ065_RS28550"
                     /old_locus_tag="EJ065_5670"
     CDS             8910..9479
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS28550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EJ065_5670"
                     /product="hypothetical protein"
                     /protein_id="WP_128798624.1"
                     /transl_table=11
                     /translation="MSPRHLAPWLLLVALVTACASSPPVEQRRQPPPRILFESPLALLL
                     ENYQELGLSTDQLIKIGQRDEALAVTNKPLREELRAIWTPPMGNNPPPGTMPVRVGPAG
                     RGGRPPYRPPAQPPAPLSEEALKRQQLLLQAMEDNETVAYREVEALLEEPQKEKARALV
                     EKQRKERARARESMRKAPEAPPEPES"
     CDS             complement(9566..9661)
                     /gene="allorf_7162463_7162558"
                     /locus_tag="allorf_7162463_7162558"
                     /protein_id="allorf_7162463_7162558"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWGRLLLDGAPRLARELRLLQTSAAFSCITG"
     CDS_motif       complement(9587..9661)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWGRLLLDGAPRLARELRLLQTSAA"
                     /locus_tag="allorf_7162463_7162558_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9566..9586)
                     /prepeptide="core"
                     /locus_tag="allorf_7162463_7162558_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="590.7"
                     /monoisotopic_mass="590.3"
                     /core_sequence="FSCITG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWGRLLLDGAPRLARELRLLQTSAA"
                     /leader_location="[9586:9661](-)"
                     /alternative_weights="608.7"
     gene            9660..9884
                     /locus_tag="EJ065_RS28555"
                     /old_locus_tag="EJ065_5671"
     CDS             9660..9884
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03898.1"
                     /locus_tag="EJ065_RS28555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5671"
                     /product="mersacidin/lichenicidin family type 2
                     lantibiotic"
                     /protein_id="WP_205694646.1"
                     /sec_met_domain="L_biotic_A (E-value: 0.00014, bitscore:
                     20.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTPDLIIRAWKDPSFRESLTAEQRAQLPANPSGTTVNEMSETEL
                     MDVVGGKIDIGFTATNSCEYICTNMTFVC"
     CDS_motif       9660..9812
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MMTPDLIIRAWKDPSFRESLTAEQRAQLPANPSGTTVNEMSETELMDVVGG"
                     /locus_tag="EJ065_RS28555_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9813..9884
                     /prepeptide="core"
                     /locus_tag="EJ065_RS28555_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.40"
                     /molecular_weight="2484.9"
                     /monoisotopic_mass="2483.1"
                     /core_sequence="KIDIGFTATNSCEYICTNMTFVC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMTPDLIIRAWKDPSFRESLTAEQRAQLPANPSGTTVNEMS
                     ETELMDVVGG"
                     /leader_location="[9659:9812](+)"
                     /alternative_weights="2502.9"
                     /alternative_weights="2520.9"
     gene            10001..13222
                     /locus_tag="EJ065_RS28560"
                     /old_locus_tag="EJ065_5672"
     CDS             10001..13222
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002611665.1"
                     /locus_tag="EJ065_RS28560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5672"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_128798625.1"
                     /sec_met_domain="DUF4135 (E-value: 6.9e-100, bitscore:
                     333.6, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.1e-67, bitscore:
                     226.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREGSKMGAWERAAFLHEREAAGEDPPAPALQQAESRLQKWRRGT
                     LGDEASFDERLRAVGLDAAAFVRRLAGSAPRPEALTWLPLLEEVLSDRAADVALPSPVD
                     SGPRMRVPSLTRRFLQLGLRRLRAGVEALAARTGCAPGALLDARAEAWLVDALEQRLIQ
                     TATRALVLELNVARLSGELQGETPQARFEHFALRHLEAPGRLAAFLEEYPVLARLLVTA
                     LDRWSRTSLELLTHLAEDREALVAVLGAGVDPGPLVEARTGAGDLHREGRSVALLTFRS
                     GLRVVYKPRSLEVEARYQDLLEQLERWGLRHPHRRLKVLTRASHGWVEHVETGGCDDRD
                     AVARFYWRQGSHLALLYLLRGVDLHSGNLLADGEFPVLVDLEGLFHQLPAPRADDTAAS
                     RAARFLERSVISSGLLPTLMFGREGRAGVELSGLGGEAGQLFPHATPTLEDRARDTLHV
                     VRRQPATAGAHNRPLLEGRPVDVTAFGACIEEGFQETYGLLLQHREEVARTLEGLRDVE
                     VRHIARATMRYGFLLQEGLHPDFLRDALDRDQLLDKLWAEVRVRPSLARLTPSEHEDLR
                     LGDVPVFTARPGSRHVWDSRGRCIPDHLPRAGLEGSLQLLEDLGPEDCADQVALIRQSL
                     VTLEREQETVAPRAPVTAAGEALPPPATPDACLAGAVQLGELLAARAIQGAHDVGWIGV
                     GLQDLERRRWGLSPLRTDLFDGVGGVALFLGYLAAVTGREDFATLARRAAVPVREQWRA
                     PGSQDPSGVGAFSGRAANVYVLGHLAVALGDAALLEEVHAGLGSLEAKIDADTALDLVT
                     GVAGTALVLTRLHQQTGSGEALRLARRCGERMLQTASDSEHGGRAWVVPAAGRALTGLA
                     HGAAGFVWALLELATLTGDERYREAARQGLAFERALFVPERGNWKDVRTSKEGEPLVPG
                     GFMTAWCNGAAGGVLARLLSLRHLDDARLRDELRAGLATVQREGFGGSHCLCHGDMGNL
                     EVLHLAGEVLGDEAWKEAAYSRAARVLAQGQDETWRCGLPRFTEAPGLMLGLAGIGMGL
                     LRLAAPDFVPSVLALQPPRTPGPRF"
     gene            complement(13270..13392)
                     /locus_tag="EJ065_RS40790"
     CDS             complement(13270..13392)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS40790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_276320208.1"
                     /transl_table=11
                     /translation="MRDDGLLGQCELDASCNPTCWGVESAYPVYSDYFYCTHCP"
     CDS_motif       complement(13366..13392)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRDDGLLGQ"
                     /locus_tag="EJ065_RS40790_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13270..13365)
                     /prepeptide="core"
                     /locus_tag="EJ065_RS40790_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3434.8"
                     /monoisotopic_mass="3432.4"
                     /core_sequence="CELDASCNPTCWGVESAYPVYSDYFYCTHCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDDGLLGQ"
                     /leader_location="[13365:13392](-)"
     misc_feature    complement(13951..13964)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.61"
                     /tool="antismash"
     CDS             complement(14190..14366)
                     /gene="allorf_7167087_7167263"
                     /locus_tag="allorf_7167087_7167263"
                     /protein_id="allorf_7167087_7167263"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRLGAKITSGRSFLQGRHLVERVIRRAGQGMQRWTRGSRSAARAR
                     GLVRARRPECPGS"
     CDS_motif       complement(14274..14366)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRLGAKITSGRSFLQGRHLVERVIRRAGQGM"
                     /locus_tag="allorf_7167087_7167263_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14190..14273)
                     /prepeptide="core"
                     /locus_tag="allorf_7167087_7167263_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.40"
                     /molecular_weight="2966.3"
                     /monoisotopic_mass="2964.6"
                     /core_sequence="QRWTRGSRSAARARGLVRARRPECPGS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRLGAKITSGRSFLQGRHLVERVIRRAGQGM"
                     /leader_location="[14273:14366](-)"
                     /alternative_weights="2984.4"
                     /alternative_weights="3002.4"
                     /alternative_weights="3020.4"
     gene            14381..14752
                     /locus_tag="EJ065_RS28565"
                     /old_locus_tag="EJ065_5675"
     CDS             14381..14752
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013375273.1"
                     /locus_tag="EJ065_RS28565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5675"
                     /product="HNH endonuclease"
                     /protein_id="WP_128798626.1"
                     /transl_table=11
                     /translation="MAGKLKTRVNSSGYKQFWDKDEERWVFTHRRVAEKKIGREPVPGE
                     EVHHINGDKEDNRSRNLVVLKDSIHDRVHHDDPDACFRCGRSGHWAEDCYAKTDFEEDA
                     IDEDDFDEDEDWDDEDDDY"
     gene            complement(14759..15115)
                     /locus_tag="EJ065_RS28570"
                     /old_locus_tag="EJ065_5676"
     CDS             complement(14759..15115)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013939350.1"
                     /locus_tag="EJ065_RS28570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5676"
                     /product="hypothetical protein"
                     /protein_id="WP_128798627.1"
                     /transl_table=11
                     /translation="MKTVDEWKATMRAALKDALRTRNAPASAVLRETLAAIDNAEAPDV
                     SVAPAPVGGGIAGSAGGLGSGEIPRLLLSPEAVEALIQREVQERRDAVALYTQLGKHEE
                     ARTLQAQVDVLLAL"
     gene            15253..16617
                     /locus_tag="EJ065_RS28575"
                     /old_locus_tag="EJ065_5677"
     CDS             15253..16617
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020337.4"
                     /locus_tag="EJ065_RS28575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5677"
                     /product="CotH kinase family protein"
                     /protein_id="WP_164933337.1"
                     /transl_table=11
                     /translation="MARFGAWMKDRGRARRGSPHVALALLVLALGLAASGCRPQSPWGP
                     PVPECTGTGDAAREDAAREHGQAPRAYVEEDGLPVLHLYVADSLPDDDEYQAARVFYRG
                     RCYAARARYRGATSKVFPKRSFTLDFLGGQTFDEPLLAAGFTGRRKVVLISPFNDNSYL
                     RARLGFTLWSRMSPGHLEVKTFSAVVYLNGRYHGLYTVADHVDRHSLSAQGMDVQGELF
                     KAVDSDANFSWRDASGRPKASLRLGYEKKEGDPEEGDGAYASIEQLTAFVADSHAERFR
                     AERGAWMQVEDYEDWWIFAHLAALSDSVTKNAYHFRAQGQARRWRYIPWDLDASFGQNW
                     DTTRQAPDVMDSFTEENRLFARMLEDPAIRQPLRERLHTLIHTTLHRDVVQGLIDTYAA
                     EVDRAARKDEAHWGEAYRHFPRWNQRTDILGFEEEVRYLHDWVDAHWALLEEELR"
     gene            16685..18082
                     /locus_tag="EJ065_RS28580"
                     /old_locus_tag="EJ065_5678"
     CDS             16685..18082
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011551099.1"
                     /locus_tag="EJ065_RS28580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5678"
                     /product="chloride channel protein"
                     /protein_id="WP_128798629.1"
                     /transl_table=11
                     /translation="MAGRREPLDEEQRALHDSWDTVLRTVGRVVLSTVLIWGVCSALRY
                     GVHATSDALLAFASGQSVWWAPLVLAGVLLLGGLLRGVLNRRPGWSDVASDGVNVALHN
                     YHITYEDSADDPRPRYSRPALRLALRKAVATLLTLGSGASGGLEGPVVLVGESLGAGVA
                     RLTRASSEHTLRTCQLAGIAAAVGTLLNAPFAAALFALEVVYGNRIVYRKLAYCLLAGI
                     IAYALNNRFLGFKPIFVAPPHAHTYTLGEYGLTALVAVAVSAPIALLFGLSMQHTRKVV
                     ERASPLLRGAMGALCTVLVAGGLYYGVGMDFRHVLGMGEYTIAQLLTGASGTLSLWWFL
                     LLIVGGKLLTTSFTVQSGGSAGMLIPSMVLGGVSGAATAQLLASLTGTGPADVTVFVVV
                     GIASALVAVVGVPLAAIALVLEVFGSAYGPPAVLACCVTYVLTLRLSVYNEQRRVRAVA
                     AESVAEA"
     gene            complement(18110..19099)
                     /locus_tag="EJ065_RS28585"
                     /old_locus_tag="EJ065_5679"
     CDS             complement(18110..19099)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398768.1"
                     /locus_tag="EJ065_RS28585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5679"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_128798630.1"
                     /transl_table=11
                     /translation="MIFHVVLDGVAEGPLGVGLDVINTASRLLESGLVPGAPRANPLRQ
                     RVVSLDGRPVRSGTGRSVCVDGALNLRSVKAGDVLLVPGLSAASERAVEQLLSRADTVR
                     GMELLARAAAKGARVAASCSATFVLAAAGLLEGRNATTTWWLVPAFVRRFPQVTVRADR
                     MVIESDGVLTAGSAFAHADLMLAIVARVASPSLAHLVARYLVLDERVSQSRYMVMEHLR
                     VSDPALRSVERFITANLGRQLTLAELARAAATSSRTLARRVQAGLGMTPLEFVQRVRVA
                     HASHLLETTRDSVDDVAARVGYADAAAFRRVYRRYAGESPRGRRPSRP"
     gene            19175..20038
                     /locus_tag="EJ065_RS28590"
                     /old_locus_tag="EJ065_5680"
     CDS             19175..20038
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015347494.1"
                     /locus_tag="EJ065_RS28590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5680"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_128798631.1"
                     /transl_table=11
                     /translation="MTPPAPEPTADDPLDDFERRTITLQSAPRTAYVAGRGPAVIVLAE
                     MPGISPHVARFARWVRDAGFTVYMPSLFGRDGAYPQAEAGLAVMKRACVSAEFRAFAAN
                     ASSPVTQWLRALASLAHQECGGPGVGAIGMCFTGNFALSMMLEPAVLAPVLCQPSLPLD
                     NPGAIQIAPEEAAAVKERLEREDLTVLAYRFDGDRFCTAQRFAAYAEALGPRFHPRVLP
                     SSAANPNPPPFFERIVGGAHSVVTAHLIDAAGEPTLAARDEILSFFARRLHPEAVAPPG
                     PITPLR"
     gene            complement(20022..20786)
                     /locus_tag="EJ065_RS28595"
                     /old_locus_tag="EJ065_5681"
     CDS             complement(20022..20786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013938755.1"
                     /locus_tag="EJ065_RS28595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5681"
                     /product="hypothetical protein"
                     /protein_id="WP_128798632.1"
                     /transl_table=11
                     /translation="MRSLFIWALVLFSTTALAAETRLVVRARARDGKFIGTSMGGVRVV
                     LRDGQTGELLASGVTAGSTGNTQTLMKQPQVRGAPLADASSAKFTATLDLAEPRLVTVE
                     VSGPLAQRQALATSTTQLWLLPGKHLEGDGLILELPGFVVDVLTPSAHEFIKLAKDKKL
                     TVPLRANLTLMCGCPTEPKGLWDSSRYELQATVKHNGKPLTQLPLKYAGKTSTFEAELS
                     VQQQGAYEVTVTAYDPVTGNTGVDSTTFIVEG"
     gene            complement(20813..21568)
                     /locus_tag="EJ065_RS28600"
                     /old_locus_tag="EJ065_5682"
     CDS             complement(20813..21568)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /locus_tag="EJ065_RS28600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5682"
                     /product="DNA alkylation repair protein"
                     /protein_id="WP_128798633.1"
                     /transl_table=11
                     /translation="MNATPAATEELRRTLKARSDPRLAEATRRYFPTDIRALGVRNAEV
                     RRIADAFIKERGLSPEDRLAVTEALLAQATHHEEVLLGFALVRKAVGRSFDESLLDRFR
                     YWLEHFVWNWAQCDDLCLTVLYPFFLTRTPALTRIQHWTGSRSPWCRRAANVALVKFVS
                     RGIRSSRYMLPREVILGNAQRLLSDPEPYVQKSVGWLLKVAADHHREAVVAFIQENISG
                     MQRDTLRYAIERLEPAQRKALLALEYKTS"
     gene            complement(21718..23085)
                     /locus_tag="EJ065_RS28605"
                     /old_locus_tag="EJ065_5683"
     CDS             complement(21718..23085)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014398777.1"
                     /locus_tag="EJ065_RS28605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_5683"
                     /product="hypothetical protein"
                     /protein_id="WP_240672483.1"
                     /transl_table=11
                     /translation="MDIRNLPACIREVALAAQDTDPGPPEPTDYHQLRGRLEAARATLP
                     PLYRDAVLVPYLKTLDQIGPQGFADTLVRDPRRESEAGLLMDAAHAILQNGEGYQCIAT
                     DAFEEVVSDLYDGFLSAEDRRGVHPPDQGTLAPLVKWGNPDFGPYTWPVDATFSVLGLE
                     CGIVNLPPSQGRAGLLAWAALGHEVGGHDILHADTGLAEELSTVVYDRLQKQGLSALAN
                     YWARRIDETASDVLGILNMGPAAGIGIIGYFRGLDTAFGGAGRLRNVGGSSDPHPADIV
                     RGYLAGSVVKRLRFSQAEAWAQVIFDEVDKDLDPAELRLGTQRVTPEQARLSADLVADA
                     IMTHRAKALEGQSLAWIQNWRNHDEQRVQQLRRRLATGVGTLTEELSTGIYAAHVVAAG
                     VVAGLTEQADVRKIFDRMVRMLKQMHDRNPAWGPLFVRHRGDVVPHFIYPFPARRT"
ORIGIN
        1 gagagcttcg cgttgctgaa ccggccgacc gccacctcct tcaggtggtt catgtcggtg
       61 acccagtccg ggctgcccgc gctgttgacc agcgcctgcc ccagcgcgcg tccgccgctg
      121 ccgctccggc tgccgcgaaa gaccaccgtc agccgctcga ggtcggggtc gtagatggcg
      181 gcgcccatcc agctgggcca gcccgccgtg gggtgcgtct gcgtcatccc cgtcttgccc
      241 tggaagtagc agcaccgctt cgagccgctc gcctcggagt gctccaggcc cagccgcgtc
      301 cgctccccga agagttcctg gaccttgatg gggatgtcct ccccctccag gtccacgccc
      361 ttcgagaagg agatggagcg gtccagctcc cgaggctgga acaggatgta cggagcggcg
      421 cccgtgccgc cccggtacac gaccccgctc cgggggttcg gcggagtcct caggtcgtat
      481 tcgatgggat cgaacttgtg gatgtccgct tcgctgccga gcagcttgtg cacctgggcc
      541 aggacgcgat ccctcgcgcc ctgccacatc ccggctccgt gggattcgta gaacggatcc
      601 atcggataga cacagccctg ggcgtacgcc ttgtaggcga agcggcagta ctccagcatg
      661 tccagcgccg tctcggcatt gggatgaggc acggggtgac tcctggggag cagcagggga
      721 ctccgagaat caaacgggcg ctggcgacag ggagtcaatg gagcggggct gacccacacg
      781 ggccagttgc tccagcagcg cggcacccac cgcgtcaggc gcttccagtt gcgggaagtg
      841 gcctacgtct tccagctcca gcactcgcgc ccggggcagc gcctgcttcc accgcgacag
      901 gtgctcgggc ttcacgagct tgtccgccct cccccagacg accagcgatg gaacgtccgc
      961 gagccggccc aggccctgcc cctgttcgtc catccacggg ccttcgtggg agatggagcg
     1021 cgcgaagccc caggtcccca tccgtgatgc ccggtccggg aaccgcgaca ggaaggactg
     1081 gtgcagctcc cgcgtcagct tggtgcggcg cccccaggac atcttcacca gcgtccgcgc
     1141 ggagaagttc caggacaaat acagccaccg catcagcgcg ttgtcgacgt tggggccctt
     1201 caggtcccac agccagctct gcaccaccgt gaggctcagc acccgctccg gcgccgcgat
     1261 ggcgagcggc agcgcgatgg gcccgccgaa gtcatgcacc accaggtgga acggccccag
     1321 cgccagctgg tcgaaccacg cgcgcaggtt ctccacgtgc cagggcagcg aataggtgcg
     1381 ccagtccccg ggcctctcgc tgtcaccgaa gcccaggtgc tctggcgcga gcacgcggta
     1441 ggacggcgag agccgccggg ccacgtcccg ccactcgcgc gacgacgaag gcgtgccgtg
     1501 caccagcacc accggcgtgc cctgcccttc ctcatgccac gccatctcac cgcctggaac
     1561 cttcagccgc ttcatggggt gtctgccttt cgcttgcgtg agggagtcgc gggccacctc
     1621 cgggccgcgg cgcgaatcac cttggcggcg gggtagccgc cttcgtgctg cacgtattgc
     1681 tgggagatgc cctccaccag ggcgaagagc acccgcgctt cgatgtcagc ctccggcacc
     1741 ccacgcgccg ccagtgccgc tttcagccgc tggtgcgtgg cccccaggaa gtgctcaaac
     1801 ggcagcttca gccgcgccag cacctccggt tggtgacgca ggccctggct cagccgccag
     1861 aggtcccggt gcgcgtccat catctccacg gcggacgtga gcaggaccgt gacgaagccc
     1921 cgcgcggtgg gctcgaggtc cgcggcctcc agcgtccgcg cgacgtccag catcgacgac
     1981 tgcatcagcg ccgaaagcac cgcctccttc gatgcgaagt gcgaatagag cagccccacg
     2041 gcgatgtccg cctcctgcgc gagcgcgcgg acagaggtcc catcaaagcc gtgccgggag
     2101 aagagccgca ccgcggcctg gagcacgcgc tcccgcgtct tctcccggag gactgcattg
     2161 gcgtcagccg tacgaggcat gccccacatc attgagtgaa cgttcgctca atgtaaagag
     2221 cttcaacctg gcgtgccttg gtgccttccg gttcgcaagg gagacctgcc agaccttggc
     2281 cacctacggc aggggtcgca ggtccggctc gacgatgcct ggcaaacaca cacgggccgc
     2341 gacactgaaa gccgtattga ccagtttttc aagaatagct aatttcacgg cttgtgcgag
     2401 ggcttccgac ccggtgcccg cacgttccct gagaggccga atgaaactga aactgaccca
     2461 ggcggtgagc gccatctccc ttctggccgc ggcgtgcggc ccgatgccgg agggcccgga
     2521 gtccgacagc gagcagatcg gtcagacggc gcagatgatc cgccgcgagc gggccatccc
     2581 caacgagtac atcgtcgtcc tgcgcgactc gacgcaggag gtccggcagc agggcgcggc
     2641 gaacatcgcc cgggagctgg tgtcgctcac cagcggccgg gtgctgcgga cctacgagca
     2701 ctccatccac ggcttcctgg cgaacatgac cgaggccgag gcccgccgcc tcctgtccga
     2761 cccgcgcgtg gcgtacgtgc aggagaacgg cctcatccac gtgtccgcga cgcagaccaa
     2821 cgcgacctgg ggcatcgacc gcatcgacca gcgggacctg ccgcgcaaca gctcctacac
     2881 gtacaacgtc gacggcaccg gcgtgcacgc gtacgtcatc gacaccggca tccggcagac
     2941 ccacaccgag ttcaccggcc gcatcggcaa cggctacgac ttcatcgaca acgacagcga
     3001 cccgtctgac tgccacggcc acggcacgca cgtgtccggc acggtgggcg gcacgacctg
     3061 gggcgtggcg aagaaggtca ccctccacgg cgtgcgcgtg ctggactgca cgggctacgg
     3121 caacgacgcg caggtcattg gcggtatcga ctgggtggcg gccaaccacg tcaagcccgc
     3181 ggtcgccaac atgagcctgg gcgatgtggg catccaggcc atcgacgacg cgacggagcg
     3241 gctgatcgcc gcgggcgtca ccacggtggt cgccgccggc aatgacagcg ccaacgcctg
     3301 caactactcg ccggcccgca cgcccaacgc catcaccgtg ggctccacca ccagcagcga
     3361 cggccgctcg tcgttctcca actacgggac gtgcgtggac atcttcgcgc cgggctcgag
     3421 catcacctcc gcgtcgaact ccggcaactc gtccagcacg tccatgagcg gcacgtccat
     3481 ggcgtcgccg cacgtggccg gcgccgcggc gctctacctg ggcgccaacc ccaccgcggc
     3541 gcccgcgcag gtgcgtgacg cgctggtgaa caacgccacg ccgaacaagg tcaccagccc
     3601 ggggaccggc tctcccaaca agctgctgta cacgctcttc atcaccggcg gcggcggcag
     3661 cgacaccacc ccgcccacga cgtccatcac ctcgcccgcg ggcggcgcca cgctgagcgg
     3721 caccgcgagc ctgagcgcca gcgccaccga caacgtgggc gtatcgcgcg tggagttcta
     3781 cgcgggcacc acgctgctgg gcacggcgac ggcctcgccg tacagcctct cctggaacac
     3841 ggcgacggtg gccaacggca cctacgcgct gaccacgaag gcgtatgacg cggcgaacaa
     3901 cgtgggcacg tcctccacgg tgtcggtgac ggtgaacaac ggcacgggca gctgctccat
     3961 caccgagcag ctcttcgtca acgcgggctt cgagagcggc aacacgggct ggaccacgtc
     4021 gtccggcgtc atcgacggca ccacgtccgg cagcgcgccg cgcacgggca cgtacaaggc
     4081 ctacatgaac ggctacggca ccacgcgcac cgatttcgcc taccaggacg tcaccatccc
     4141 cgcctcggcg tgcagcgcca cgttcacgtt ctgggcacgc atcacctcgt ccgagacgac
     4201 gaccacgacg gcctacgaca agctggccgt ccaggtccgc aacagcgcgg gcacggtgct
     4261 ggccacgctg gccacgtaca gcaacctgga caagggcacg gcctacgtcc agcggacgtt
     4321 caacctggcc gcgtacaagg gccagacggt ccgcatctac ttcaacggca cggaggactc
     4381 gtcgctggcg acgagcttct tcatcgatga cacggcgctg accgtcgtcc ggtagtcctc
     4441 cgccaggacg tggatgtcca gaggcccagc aaccccaccg ggttgctggg cttctgcttt
     4501 cggtgtccat gcatggcgcc accccatggc gcgcggctgc gatggcgcgc aggcggtcct
     4561 ggtcatcccg gcccgggcgg cccgcgccgg gcttcggctc cttccgtacg cccgccaggg
     4621 tcggcggagc gggcgcctgg aagagctcga atccgcgttc gatgaacgcg cctgtcgagc
     4681 gcttcgccct gcaccttgag ccgcgaagcg cttctccacg ggcacggtgt agaacgggga
     4741 agccatgccc ctccgcccgt tgcccttcgc cctcctcgcg ctgtttgtct cacttggcgc
     4801 ctccgcccag gcccccaggt ccccgctggg gcccatctcc cccaccaccg gactggtgct
     4861 tcgggacgac gtggtgcgtg cgctcatcca ggagagctcg ggcgaccgca tccatgacgg
     4921 cgtgcagcgg ctgtccctca tcgcgcggga cagcgtggat ggctacgcgg aggcggccac
     4981 ctggacgaag gccgccgccg aggccgcggg gctccaggac gtccagttgg aggcgatgaa
     5041 ggacggtccc cagtggcggg ccacgcacgg cgagctgtgg gtggccggtc cccaccggta
     5101 ccgggtgacg tcccatgccg accagcccat gtccctggcc atcggaagcg ggagcttcga
     5161 gggctcggac ctggagctcg tcgacgtgga cacgggcacc caggacgcgg agtacgcggg
     5221 caaggacttg aagggcaagg tcgtgctcac ccggggcctc ccctcggccg cgctgcgcaa
     5281 tggcgtgttg aagctgggcg ccgtgggcgt ggtgtcgtcc tattcgacgc cgccctggaa
     5341 cctccccaac cgcatggacg gagacttccc ggatcaagtg ggctgggcct acgtctcgcg
     5401 gagcctgatg ccgcagggcg cgcggacacc cttcgtgttc atggtgtcgg accggcaggc
     5461 gcgcgagctg cgcgcccagc tgcgggaggg gccggtgaag gtggacgtga gcatcgccac
     5521 gcaagcgccc acgggacacc tcagcatcgt cagcggcgtc atccccggga cacgcgcggg
     5581 agaggaggtc gtcctcaccg cccacctgga ccactacaag cccggcgctg acgacaacgc
     5641 ctccggcgcc gccacgctgc tggagctggt gcgcacgtac accacgctca tccgccgggg
     5701 cgtgctgccg ccgccggtgc gcacgctgcg cgtgctgtgg ctgccggagt tcgagggcac
     5761 ccgcgagtgg ttctcccacc acggcgcgga tccggtgcgg cgggtggcgc agttcaactt
     5821 cgacatgctc ggcgccagca tgacgcgcgt ccactcgcgc ttccaggtct cctacacccc
     5881 ggactggaac ggcagcttcg tgaacgccgt gtccgagtcc acggtggcct tcatgaaccg
     5941 cttcaacgga gtggcctatc ccccgaggaa ggacttccgc atcgggtcgg tcaccggctc
     6001 gcgggacccg atggatgcgc acatggagcg ctacggccgg ggttcggatc accagctctt
     6061 caacgaccac ggcatccccg gcgtcgccta ctccacgtgg ccggatgacg gctaccacac
     6121 cagcggcgac aggccggaga acgtggaccc cactcagttg caccgcgccg ccttcgcggg
     6181 cctggccggc atcaccgtcg ccgcgtgggc ggaaggcacg ggcgccctgg agctctcgcg
     6241 cctggtggcg gtgcacggcg cgaagcgcgt ggccgaggac gagttccggg cccgccgcga
     6301 gctggccgcg acgcccgccg cgcaggtgcc cggcttcgcg cgcctggccc gcgccggggt
     6361 gcgcgcgggc taccagcgcg aacgcgacgc cctgcgctcc tgcctggccc tgggcgcgcc
     6421 cgccgagccg gtgaaggcga tggtccaggc gctggagacc gccgagtccc aggccctcaa
     6481 gcgcctggac gcggacggga aggcgcgcgg ggtgtccctg aaggagccct caccgggcga
     6541 agccgagcgc aaggcgcggg ccttcgttcc gcgtcgcgtg aagggccagg agctcgcgtc
     6601 gttcgacgag ttggagcgca acgcgcccac cgcatccaag gcccgggtgg acgcggtgaa
     6661 ggccgccatg accgccgcgg ccacggccct gcgcgagcag ggggagagcg agctgcgctt
     6721 ctaccaactg gcggatgcgc tcgcgagcta cgccgacgga aagcgctccg tggcggacat
     6781 ccgagacgcg gcccatgccg agtacggata tgtctttccc gtggaggcca tgctggacct
     6841 gttcgggctg ctggagcagg gcggcatcat gacgcgcgga cgctaggtgt acttcggcgg
     6901 gccgcggcgc caccttccat ctccaggtga cgggaggcca ggagccgggg cagcgctccc
     6961 tttctcagca gcgctcccat ttctcctatg tttcagtgcg atcccccacc gcgcctccag
     7021 gtcctcccca tgctccgccc gcgactcgca gcccttgccc tgctcccgct cgtctccgcc
     7081 tgctccaacc ctgagtgcac ggacaccgcg gattgtgcgt cccgaggccc cgacatcgtc
     7141 tgcgttgaag aacgctgcgt tcaagcgtcc tcgccagacg caggtgcggg tgactcgggc
     7201 gtggacgcga gcactcccga cgcgggtacc gaggacgcag gcgctggcga cgcgggctcc
     7261 ctggatggcg gcggctccac gccagaagcc tcgcttcgca tcaccgagat caatccagac
     7321 gccccgcagg acctcatcga gctggtggct gtcaccggcg ggacgctgac cggcatctcc
     7381 ctccaggagc tcaccaactc cgacttcgcc ttcaccttcc cccagggctt cacggtggag
     7441 acgggcgccg tgctggtgct tcacctcgga ggctcctgca ccgacgctcc cggcgacccg
     7501 gcctcctgtg gacagaccgc gcccttcagc gccagtgcct gggacttcag catgcctggc
     7561 acgctgagct actccggcaa ggtgcttgaa ttgctgtcgt cgaaatccgt gcctgtcgac
     7621 ggcgttccct tcgtccgggc ctccggggag atgcccttga gcatcgtcgc cgccatccag
     7681 cgcctgcaag ccgaccgcgt ctgggatgcc acgccctgca tccacgacat gaccaccggg
     7741 ttcgcgaagg accgctactg ccgcaacatc gccgcggact ggtccggcct caacgagagc
     7801 tccagcatca tgcgcatcag tggcaccacg ccgctgacga cgccggggct caagacccaa
     7861 tggagtgggc cgcttccctc gcgctggggc tcctactgag gcccttgcgt gtcggagctc
     7921 aggcttccga cgccgtcttc aacccggccg gaggtggggc gtgcagccgc aggcgctccg
     7981 ccgtgagcgg atgcgtgaac gcgagcgtct ccgcgtggag caggtagccg ccatctccag
     8041 gcagcccggg ctcgtgctcg cggggcaggc ctcccgaggc gaacatcgga tcccccgtga
     8101 gcggatggcc gatggacgcc aggtggatgc ggatctgctc ggggcgaccc gtgtggatgc
     8161 gcacctcgaa gagggtctgc ccttcacgcc gctccaggac ctccgcgcgg ctgtgtgacg
     8221 gcttgccctt cgcgctcgcc ccgtgcaccg accccagcag ggggtggggc accagcccga
     8281 tgggcgtgtg gatgtcatag gccgcctgcg ccgcgacccc gtccgacagc gcccggtagc
     8341 gcttctccac gtcgccctcg cgccagttgc cggagagctt cgcggcggct tcctgcgtgc
     8401 gggagaagag caccagcccg gaggtcgccc gccccagccg gtgcagcgcg gaggcctccg
     8461 gccagcgcag ccgcacgaac gagagcagcg tgttcttgag gaagccgcct gagggcagcg
     8521 tcggcagccc gctcggcttg atgaccgcga gcagcgaagc gtcctcgtac accagctcga
     8581 agctgtcggg cgtctcccgt tcccgccagg gcggccggtg ccagcagagc tcctggtggg
     8641 cttgcagcac ctcgtcgccg gtcgcgatga ggccgtccag tcgcacctcg ccgcgcacga
     8701 agcgcgcgcg ccactgctcc tcggtggagt gccggtacgt gcccgtcagg tgggcaagcg
     8761 aggtgcgccc cacggaggcg gcgccaatcc gctcgcggta cacatagccg tcattcaggc
     8821 cggcggagtc gtcaggctgg gacatcaccc gtgtactcta cgtcagagag cgaagcttca
     8881 cgtccgtgct catttcccaa ggaggaccga tgtcgccgcg tcatctcgcg ccgtggttgt
     8941 tgctggtggc ccttgtcaca gcctgcgcgt cgtccccgcc ggtggaacag cgacggcagc
     9001 cgccccccag gatcctcttc gagtcgcccc tcgcgctgct gctcgagaac taccaggagc
     9061 tggggctgag caccgaccag ttgatcaaga taggccagcg ggacgaggcg ctggccgtga
     9121 ccaacaagcc cctgcgtgaa gaactccggg ccatctggac cccgcccatg ggaaacaatc
     9181 cgccgccggg aaccatgcct gtcagggtcg gccccgcggg ccggggcggc cggcccccgt
     9241 acaggcctcc ggcccaacct cccgccccct tgagcgaaga agcgctgaag cggcaacagc
     9301 tcctgctcca ggcgatggag gacaacgaga cggtggcata ccgcgaggtc gaagccctcc
     9361 tggaggagcc tcaaaaggag aaggcgcgag cgctggtcga gaagcagcgt aaagagcgtg
     9421 ctcgcgcacg tgagtcgatg cggaaggccc ccgaagcccc acccgagccg gagtcctgaa
     9481 ggtgtctcgg cgcgggacgc ttcaccccgc gtgaggcccc tcccacgcgc cagggggaat
     9541 ggggcgcccg cgactcacac cggcatcacc cggtgataca tgaaaaggcc gcggacgttt
     9601 gaagcagccg gagttcgcgg gctagcctgg gagcgccgtc taaaaggagg cggccccaca
     9661 tgatgacccc cgacctgatc atccgcgcct ggaaggaccc gtcgttccgc gagagcctca
     9721 ccgccgagca gcgcgcccag ttgcccgcga acccctccgg cacgacggtg aacgagatga
     9781 gcgagaccga gctgatggac gtggtcggcg gcaagatcga catcggcttc accgccacca
     9841 actcctgtga gtacatctgc accaacatga cgttcgtgtg ctgatggacg gtgtgtgacg
     9901 ggcggctccc acgaggagtc gtcccgtacc acccgaggcg cgggggctcc ggctctcgcg
     9961 cctgtctttt tccaagtcca gacggacatg cagggcgcgc atgcgagagg gctcgaagat
    10021 gggtgcgtgg gagcgggctg ccttcctcca tgagcgggag gccgcgggag aggatcctcc
    10081 cgccccggcg ctccagcagg ccgagtcgcg cctccagaag tggcggcgcg gcacgctggg
    10141 ggatgaggcg tccttcgacg agcggcttcg cgccgtgggg ctggacgcgg cggccttcgt
    10201 gcgcaggctc gccggaagcg ccccgcggcc ggaagcgctg acgtggctgc cgctcctgga
    10261 agaagtgctg tcggaccgcg cggccgacgt cgccctcccc tctcccgtgg actcgggtcc
    10321 acggatgcgc gtgccgtccc tgacgcgccg gttcctccaa ctgggattgc ggcggctgcg
    10381 ggccggcgtg gaggcattgg ccgcccggac cgggtgtgcc cccggcgcgt tgctggacgc
    10441 gcgcgccgaa gcctggctcg tggacgcgct ggagcagcgg ttgatacaga ccgcgacccg
    10501 ggcgctggtg ctggagctca acgtggcccg gctgagcgga gagcttcagg gcgaaacgcc
    10561 ccaggcgcgc ttcgagcact tcgccctgcg ccacctggaa gccccaggcc ggctcgccgc
    10621 gttcctggag gagtacccgg tgctggcgcg gctcctggtg acggccctgg accgctggag
    10681 ccggacgagc ctggagctgc tgacgcacct ggcggaggac cgcgaggccc tggtcgccgt
    10741 gctcggcgcg ggggtggatc caggaccgct cgtggaggcg cgcactggcg cgggagacct
    10801 gcaccgcgag ggccgcagcg tggcgctgct gaccttccgc tctggcttgc gggtcgtcta
    10861 caagccgcgg tcgctggagg tcgaggcgcg ctatcaggac ctgctggagc agctggagcg
    10921 ctggggcctg cgccatccgc atcgccggct gaaggtgctg acgcgcgcgt cgcatggctg
    10981 ggtggagcac gtcgagaccg gcgggtgcga cgaccgcgac gccgtggcgc gcttctactg
    11041 gcggcagggc agccacctgg cgctgctgta cctgctgcgc ggggtggacc tgcactccgg
    11101 caacctcctc gccgacggag agttcccggt cctggtggac ctggaggggc tgttccacca
    11161 gctgcccgcc ccacgcgctg atgacacggc ggcgtcccgc gccgcgcgct tcctggagcg
    11221 gtccgtgatc agcagcggcc tgctgcccac gctcatgttc ggcagggagg gccgtgccgg
    11281 ggtggagctg agcggtctgg gcggcgaggc aggtcagctc ttcccccacg ccacgcccac
    11341 gctggaggac cgcgcccggg acaccctgca cgtcgtccgc cggcagccgg ccaccgcggg
    11401 cgcccacaac cgcccgctgc tcgagggccg gcccgtggac gtcacggcgt tcggggcgtg
    11461 catcgaggag ggcttccagg agacgtacgg gctcctgctc cagcaccgcg aggaggtggc
    11521 gcgaacgctc gaggggctcc gggacgtgga ggtacgccac atcgcccggg cgacgatgcg
    11581 ctacggcttc ctcctccagg agggcctgca cccggacttc ctgcgcgacg cgctcgaccg
    11641 ggaccagctg ctcgacaagc tgtgggcgga ggtccgcgtg cgtccttcgc tggcgcggct
    11701 gacgccctcc gagcacgagg acctccggct gggcgacgtg cccgtcttca ccgcgcggcc
    11761 cggctcccgc cacgtctggg acagccgggg gcgctgcatc ccggatcacc tgccgcgcgc
    11821 cggcctggag ggctcgctcc aattgctgga ggacctgggc cccgaggact gcgccgacca
    11881 ggtggcgctg atccgccagt ccctggtgac gctcgagcgc gagcaggaga ccgtggcgcc
    11941 ccgcgcgccg gtgaccgccg ccggggaggc cctgcccccg cccgccacgc ccgacgcgtg
    12001 cctggccgga gcggtccagt tgggcgagct gttggcggcc cgcgccatcc agggtgccca
    12061 cgacgtcggc tggattggcg tggggctcca ggacctggag cgccgtcgct gggggctctc
    12121 tcccctgcgc acggacctct tcgacggcgt ggggggcgtg gcgctcttcc tcggctacct
    12181 ggctgcggtg acgggccggg aggacttcgc gacgctggcg cgcagggcgg cggtgccggt
    12241 gcgcgagcag tggcgcgcgc ccgggtccca ggacccctcc ggcgtggggg cgttctcggg
    12301 gcgcgcggcg aacgtctacg tcctcggcca cctggccgtg gccctgggcg acgccgcgct
    12361 gctggaggaa gtccacgccg gcctgggctc gctggaggcg aagatcgacg cggacacggc
    12421 gctggacctg gtcacgggcg tcgcggggac cgcgctggtg ctgacgcggc tccaccagca
    12481 gaccggcagc ggggaggcgc tccggctggc gcgcaggtgc ggggagcgga tgctccagac
    12541 agcgagcgac tccgagcacg gaggacgcgc ctgggtggtg cccgcggccg ggcgcgcgct
    12601 cacgggcctg gcccacggcg cggccggctt cgtctgggcc ctgctggaat tggccacgct
    12661 caccggcgac gagcgctacc gggaggccgc acgtcaggga ttggctttcg agcgggccct
    12721 gttcgttccg gagcgaggca actggaagga tgtgcgcacg tcgaaggaag gcgagccgct
    12781 ggtgcccggc ggcttcatga cggcctggtg caacggggcc gcgggcggcg tcctggcgcg
    12841 gctgctgtca ctgcgccacc tggacgatgc gcggctgcgc gacgagctgc gcgcggggct
    12901 cgccaccgtg cagcgggaag gcttcggcgg cagccactgc ctgtgccacg gagacatggg
    12961 caacctggag gtgctgcacc tggcgggaga ggtgctggga gacgaggcct ggaaagaggc
    13021 cgcgtactca cgggccgcgc gggtgctggc acagggccag gacgaaacat ggcgctgcgg
    13081 cctgccccgg ttcaccgagg cgccagggct gatgctgggg ctggccggca ttgggatggg
    13141 gcttttgcgc ctggccgcgc cggacttcgt gccgtcggtg ctggcgttgc agcctccgcg
    13201 aacgccaggc ccccgcttct aatcgcggtg ggccgaacgc tcccgcgcgg tgcggcggga
    13261 gcgaggggct caagggcaat gcgtgcagta gaagtagtcg ctatagacgg gataggcgct
    13321 ctccacgccc cagcaggtgg gattgcagga cgcatccagc tcgcactgac cgagcagtcc
    13381 atcgtctcgc atagggtaag agtcccagta ggtggtgagc ctggggacgt aatattgggt
    13441 acaggcgctc gccttcacgg agcctcctgc ctcggaaacc accgacggct gccgtgcttc
    13501 gttcgcggtg ccttccaggc tggaatcgcc tccgcacgca accagacccg acgccaggaa
    13561 cgcagccaca gccaggagat gcttcatggg gcctcacctc gtgaaaggaa ctccggtgga
    13621 aggctcgcag tctggttcat cccgccccag acggaaatgc cttacatccg gcagaccgcg
    13681 tggatgtagt tccacgaaca atccactcag ggtcggtcca tggcgtggca gcgcgctgca
    13741 cggattgccc cgccgtgaat gacagcgcca tcctgaccag ccccccacga caggacaagc
    13801 atatgcgctg ggcaatcatt gccggactga tgactgcagg gctgatgacg gcctgtggag
    13861 ttcccgcagg ctgctgtgtg tgcggactgt ctgcatgagc tgcaagcctg tctgcgccgg
    13921 gccgggaatc gcccgcccgc cgtcgaggca tgcgaggcca tgcacgatga gtgctacgcg
    13981 gagatgcgcg gagggccgag tgtcgcccag gcgggactct ctcccgacaa catctgctac
    14041 atcgagtgct ggggaggacc tgccgctggg accaccgcag cgccgtacgc agccaatctc
    14101 caagagtgtt tcgcctacgc caacagcatc tgcgccgtgc cagacggcgg ctggtatggc
    14161 ctcacataca acggccaaca ctacgccaac tagcttcccg ggcattcagg ccgccgagcg
    14221 cgcacaagac cccgtgcgcg tgcggcggag cgcgagccgc gcgtccaccg ctgcatgccc
    14281 tgccccgccc tccgaatcac ccgctcgacg agatggcgtc cttgcaggaa cgaacgacct
    14341 gaagtgatct tggccccgag cctcacgcga tgggggaacg atggcaggaa agctgaagac
    14401 tcgggtcaac tccagcggct acaagcagtt ttgggacaag gatgaggagc gttgggtatt
    14461 cacgcaccgc cgggtcgctg agaagaagat cggacgcgag cccgtccccg gcgaagaggt
    14521 ccaccacatc aacggtgaca aggaggacaa ccgatcccgg aatctcgttg tgctcaagga
    14581 cagcatccac gaccgcgttc accacgatga tcccgacgcc tgcttccgct gcggacggtc
    14641 cggccactgg gctgaggact gctatgcgaa gacggacttc gaggaagatg ccatcgacga
    14701 ggacgacttc gacgaggacg aggactggga cgacgaggac gacgactact gaccgcgctc
    14761 aaagcgccag aagcacgtcc acttgcgcct gaagcgtccg ggcctcttcg tgcttgccga
    14821 gttgggtgta gagcgccacc gcgtcgcgac gctcctggac ttcacgctgg atgagggcct
    14881 ccaccgcctc cggcgacaac agcagacggg gaatctctcc acttccaagt ccccccgcgc
    14941 tgccggcgat gcctccaccg accggcgctg gggcaacgct cacgtcgggc gcctcggcat
    15001 tgtcgatggc ggcgagtgtt tcccgaagca ccgccgaggc gggcgcgttt cgagtgcgca
    15061 gggcatcctt cagcgcggcc cgcatcgttg ccttccattc atccacggtc ttcatgcgtc
    15121 cacggtagcg ggcgctcacc tgacccggca aggagcgccc cgcgcctccc acttcagctt
    15181 gtaggcgaca tgtgcctcgg tcccggagac agggcgcgac actgccctgg gagcggtatt
    15241 ggaggcgaac gcatggctcg cttcggggcg tggatgaagg acaggggacg agcgaggcga
    15301 gggtcaccgc acgtcgccct ggccctgctg gtgctggcgc tgggattggc ggcgtctggc
    15361 tgccggcccc agagtccctg gggcccgccc gttcccgaat gcaccggaac gggggacgcc
    15421 gcccgagaag acgcggctcg cgagcacgga caggctcctc gcgcctacgt cgaggaggat
    15481 ggactgccgg tgctccacct ctacgtggcg gactcactgc cggatgacga cgagtaccaa
    15541 gcggcgcgcg tcttctatcg cggacgctgc tacgccgccc gggcccgata tcgcggcgcg
    15601 acgtccaagg tcttccccaa gcgcagcttc acgctcgact tcctcggcgg gcagaccttc
    15661 gacgagcccc tgctcgcggc gggcttcacc ggccgacgca aggtggtgtt gatcagcccc
    15721 ttcaatgaca actcatacct tcgcgcgagg ctgggcttca ccttgtggag ccgcatgtct
    15781 cccggccacc tcgaggtgaa gaccttcagc gcggtcgtct atctgaacgg gcgctatcac
    15841 gggctctaca cggtggcgga ccacgtcgac cggcattcgc tctccgcgca gggaatggat
    15901 gtccagggag agctcttcaa ggccgtggac tccgacgcca acttctcctg gcgggacgcg
    15961 tccggcaggc ccaaggcctc actgcgtctg ggctacgaga agaaggaggg cgaccccgag
    16021 gagggagacg gggcctacgc cagcatcgag cagctcaccg ccttcgtggc ggattcccat
    16081 gcggagcgct tccgcgcgga gcgcggcgca tggatgcagg tggaggacta tgaggactgg
    16141 tggatcttcg cccacctggc ggccctgtcc gactccgtga cgaagaacgc ctaccacttc
    16201 cgcgcgcaag gccaggcgcg gcgctggcgc tacatcccct gggacctgga cgcgagcttc
    16261 gggcagaact gggacaccac gcgacaggcc ccggacgtga tggactcctt caccgaggag
    16321 aaccgcctgt tcgcccggat gctggaagac cccgccatcc gccagcccct ccgcgagcgc
    16381 ctccacacgc tgatccacac cacactccac cgggacgtcg tccaggggct catcgacacc
    16441 tatgccgccg aggtcgaccg cgcggcacga aaggatgaag cccactgggg cgaggcctat
    16501 cgccacttcc cgcgctggaa ccagcgcacc gacatcctcg gcttcgagga agaggtgcgg
    16561 tacctccacg actgggtgga tgcgcattgg gccctcctgg aagaggagct ccgctgaaga
    16621 cgccctggac ccggggcggc cgagcccatt tactttgtcc tcaaacgacg tagcctcccg
    16681 ctccatggct ggacgtcgcg aacccctgga tgaagagcag cgtgccctcc acgactcctg
    16741 ggacacggtg ctccgcacgg tgggccgggt ggtgctgagc acggtgctca tctggggggt
    16801 gtgctcggcg ttgcggtatg gcgtccatgc caccagcgac gcgctgctgg cgttcgcctc
    16861 cgggcagagc gtctggtggg caccgttggt gctcgcgggc gtgctgctgc tgggcgggct
    16921 gctgagaggc gtcctcaacc gccggcccgg ctggagcgac gtggcctcgg acggggtgaa
    16981 tgtcgcgctc cacaactacc acatcaccta cgaggactcg gcggacgacc cgcgcccgcg
    17041 ctactcgcgg cccgccctcc ggctcgcctt gcgcaaggcg gtggccacgc tgctgacgct
    17101 gggctccggc gcgtcaggtg ggctggaggg ccccgtggtg ctggtgggcg agtccctggg
    17161 cgcgggcgtg gcccgcctga cgcgcgccag ctccgagcac acgctgcgca cctgccagtt
    17221 ggcgggcatc gccgcggcgg tggggacgct gctcaacgcg ccgttcgccg cggcgctctt
    17281 cgcgctggag gtcgtctacg gcaaccgcat cgtctaccgg aagctggcgt attgcctgct
    17341 ggccggaatc atcgcgtacg cgctcaacaa ccggttcctc ggcttcaagc ccatcttcgt
    17401 ggcaccgccg cacgcgcaca cgtacacgct gggggagtac gggctcaccg cgctggtggc
    17461 cgtggcggtg tccgcgccca tcgcgctgct gttcggcctg tcgatgcagc acacgcgcaa
    17521 ggtggtggag cgcgccagtc ccctgctgcg cggcgccatg ggcgcgctgt gcaccgtcct
    17581 ggtggccggg ggcctctact acggtgtggg catggacttc cggcacgtgc tgggcatggg
    17641 ggagtacacc atcgcccagt tgctcacggg cgcgtctggg acgctgtcgc tgtggtggtt
    17701 cctgctgctc atcgtgggcg gaaagctgct cacgaccagc ttcacggtgc agtcgggcgg
    17761 gtcggcgggc atgctcattc cctccatggt gctggggggc gtttcgggcg cggccacggc
    17821 gcagctcctc gcgtcgctga cgggcacggg gcccgcggac gtgacggtgt tcgtggtggt
    17881 cggcatcgcc tccgcgctgg tggcggtggt cggcgtgccc ctggccgcca ttgccctggt
    17941 gctggaggtg ttcggctccg cctatggacc gcccgccgtc ctcgcatgct gcgtcaccta
    18001 cgtgctgacg ctgcggctgt ccgtctacaa cgaacagcgc cgcgtgcggg cggtggccgc
    18061 ggagtccgtc gcggaagcgt gagcgccgcc gcgaaggacg gctgggactt catggccgac
    18121 tcggccgcct gccgcgggga ctctcgccag cgtaacgccg gtacacgcgc cgaaaggcag
    18181 ccgcgtcggc gtagcccacc cgggcggcga cgtcatcgac cgagtcccgg gtcgtctcca
    18241 ggaggtggga ggcatgcgcc acgcggaccc gctgcacgaa ctcgagcggc gtcatgccca
    18301 ggccggcctg gacccgtcgc gcgagcgtgc gcgaggacgt ggcggcggcg cgggcgagct
    18361 ccgccagcgt caactgccgg ccgaggttcg cggtgatgaa ccgttcgacc gagcgcagcg
    18421 ccgggtccga gacgcgcagg tgctccatca ccatgtatcg ggactgcgaa acgcgctcgt
    18481 cgagcacgag gtagcgagcc accaggtgcg ccagtgacgg gctcgcgacg cgcgcgacga
    18541 tggccagcat caagtcggcg tgcgcgaagg cagaacccgc ggtgaggacg ccgtcactct
    18601 cgatgaccat ccggtccgcg cggacggtga cctgggggaa gcggcgcacg aacgcgggca
    18661 ccagccacca ggtcgtcgtc gcgttccgtc cctcgaggag ccccgccgcc gccaggacga
    18721 aggtcgccga gcaggatgcc gcgaccctcg cccccttcgc cgccgcgcgc gcgagcaact
    18781 ccatgccgcg cacggtgtcg gcgcgggaga gcagctgttc gacggcgcgc tcgctggccg
    18841 cggagagccc gggcaccagc agcacatccc ccgccttcac gcttcgcagg ttgagcgcgc
    18901 cgtccacgca gacggagcgc cccgtgccgg agcggaccgg gcggccgtcc agcgacacca
    18961 cgcgttgacg cagcgggttc gcgcgtggag cgcccgggac gaggcctgac tccagcaggc
    19021 gcgaggccgt gttgatcacg tcgaggccga cacccagcgg gccctcggcc acgccatcca
    19081 gcacgacatg gaagatcatg cctggcaaga atagaccgga acctgtcaat gtcgccactg
    19141 gctcgccagg gagggtttcc cgcatcgtcc gggcatgact cctcccgccc ccgagcccac
    19201 cgccgacgat cccctggatg acttcgagcg acgcaccatc acgctccagt cggcaccgcg
    19261 caccgcctac gtcgccggcc gaggtcccgc ggtcatcgtc ctggccgaga tgccaggcat
    19321 cagccctcac gtcgcgcgct tcgcacgctg ggtccgggat gccggcttca cggtctacat
    19381 gccgtcgttg ttcgggaggg atggggccta cccgcaggcg gaggcggggc tcgccgtgat
    19441 gaagcgggcc tgcgtgagcg cggagttccg cgcgttcgcg gcgaatgcgt caagccccgt
    19501 gacgcagtgg ctgcgtgcgc tcgcgagcct cgcgcaccag gaatgtggag gccccggcgt
    19561 cggcgccatc ggcatgtgct tcaccggcaa cttcgcgctc agcatgatgc tcgagcccgc
    19621 ggtgctggcg cccgtcctgt gccagccctc gctgccgctc gacaacccag gagcgattca
    19681 aatcgccccc gaggaagccg cggccgtgaa ggagcggctc gagcgtgaag acctgacggt
    19741 gctcgcgtac cgcttcgacg gcgatcgctt ctgcacggcg cagcgcttcg ccgcctatgc
    19801 cgaagcgctg gggcctcgct tccaccccag ggtgctgccg tcgtcggccg cgaaccccaa
    19861 tcccccaccc ttcttcgagc ggatcgtcgg cggtgcgcac agcgtcgtga ccgcgcacct
    19921 catcgacgcg gcgggagagc cgaccctcgc ggcgcgggat gaaatcctgt ccttcttcgc
    19981 gcggaggctt cacccggagg cggttgcgcc ccccgggccc atcacccctc tacgatgaac
    20041 gtggtggagt ccacgccggt gttgccggtg acggggtcgt acgcagtcac cgtgacctcg
    20101 taggcgccct gctgctgtac ggagagttct gcctcgaagg tgctggtctt ccccgcgtac
    20161 ttcaagggga gctgggtgag cggctttcca ttgtgcttca ccgtggcctg caactcatat
    20221 cgactggagt cccagagtcc cttgggctcc gtcgggcagc cacacatgag ggtgaggttg
    20281 gcgcgaagag gaacggtgag cttcttgtct ttcgcgagct tgatgaactc gtgagcggat
    20341 ggcgtcagca catccaccac gaagccaggc agctccagga tgaggccatc gccctcgagg
    20401 tgcttgccgg gcagcagcca gagctgggtc gtgctggtcg cgagcgcctg ccgctgcgca
    20461 agtggcccgg acacctccac ggtcaccagc cgcggctcgg cgaggtccag ggtggccgtg
    20521 aacttcgcgg aggacgcatc cgcgagcggc gcgccccgca cctgaggctg cttcatcagc
    20581 gtctgggtgt tgcctgtcga gcccgcggtg acaccgctgg ccagcagctc gccggtctgc
    20641 ccatcccgga gcacgactcg cacgcccccc atggacgtcc cgatgaactt gccgtcccgg
    20701 gcgcgagccc tcacgaccag ccgtgtctcc gctgcaaggg ccgtcgtgga gaacaacacc
    20761 agggcccaga tgaagaggct tcgcatgact cgctccgtat cagaagggaa ggtcaggatg
    20821 tcttgtactc cagcgccagc agcgccttcc gttgcgctgg ctccagccgt tcaatggcat
    20881 agcgcagggt gtcccgctgc atcccggaga tgttctcctg gatgaacgcc accaccgcct
    20941 cccggtggtg gtccgccgcc accttcagca gccaccccac gctcttctgc acatacggct
    21001 ctggatccga tagcaaccgc tgtgcatttc cgagaatcac ctcgcggggc agcatgtacc
    21061 tggaggagcg aatcccgcgg ctcacgaact tcaccagcgc gacgttcgcc gccctccggc
    21121 accaggggga acgggagccg gtccagtgct ggattcgcgt gagcgcgggc gtccgggtga
    21181 ggaagaacgg atagagcacc gtcagacaca ggtcgtcgca ctgggcccaa ttccagacga
    21241 agtgctccaa ccagtaccgg aagcggtcca gcagtgactc gtcgaacgag cgcccgaccg
    21301 ccttgcggac caaggcgaac cccagcagca cctcctcgtg gtgggtcgcc tgggcgagca
    21361 gcgcctcggt caccgccagg cggtcctcgg gcgacaggcc ccgctccttg atgaacgcat
    21421 cggcgatgcg ccgcacctcc gcgttgcgga cccccagggc tcggatgtcc gtggggaagt
    21481 agcggcgcgt cgcctcagcg aggcgagggt cactccgcgc cttcagggtg cgtcgaagct
    21541 cttcggtcgc ggcaggggtc gcgttcatcg cgccgccatc ctgcaccagt tgctggggat
    21601 tcacttcaag cggcgggtcc acgtccggcc gggccctggc gaagagcccg gccactgaag
    21661 cctggcaacc cgtactggat tgccaggcgc ttcaacctgg aggcggaggg gaccggctca
    21721 cgtcctccgg gctgggaagg gatagatgaa gtgcggcacg acgtcgcccc ggtgccggac
    21781 gaacagcggt ccccaggcgg ggttccggtc gtgcatctgt ttgagcatgc ggaccatccg
    21841 gtcgaagatc ttgcgcacgt cggcctgctc ggtcaggccg gcgacgacgc ccgccgcgac
    21901 gacgtgcgcg gcgtagattc cggtcgagag ctcctccgtg agggtgccca cgcccgtcgc
    21961 gagccggcgc ctcagttgct gcacccgctg ctcgtcatgg ttccgccagt tctggatcca
    22021 cgcgagcgac tgcccttcga gcgccttcgc gcgatgggtc atgatggcgt ccgcgaccag
    22081 gtccgccgac aggcgcgcct gctcgggcgt cacgcgctgg gtgcccagcc gaagctccgc
    22141 ggggtccagg tccttgtcca cctcgtcgaa gatgacctgg gcccaggctt ccgcctggct
    22201 gaagcgcagg cgcttcacga cactcccggc gaggtagccc cggacgatgt ccgcggggtg
    22261 tggatccgac gagcccccca cgttccgcag gcgcccggcc ccgccgaacg cggtgtccag
    22321 cccccggaag tacccgatga tgccgatgcc tgcggcaggc cccatgttga ggatgccgag
    22381 cacgtccgag gccgtctcgt cgatgcgccg ggcccagtag ttcgccaggg cggagaggcc
    22441 ctgcttctgg aggcggtcgt agaccacggt ggacagctcc tccgcgagcc cggtgtcggc
    22501 gtggaggatg tcgtgcccac cgacttcgtg tccgagcgcg gcccacgcga gcaggcccgc
    22561 gcggccctgc gagggcggga ggttgacgat gccgcactcc agccccagga cggagaaggt
    22621 cgcgtccacc ggccacgtgt acggcccgaa gtccgggttc ccccacttca ccagcggcgc
    22681 gagggtgccc tggtccggag gatgaacgcc ccggcgatcc tcggcgctga ggaagccgtc
    22741 gtacaggtcg ctgaccacct cctcgaacgc atccgtggcg atgcactggt acccctcccc
    22801 gttctggagg atggcgtgtg ccgcgtccat caggagcccg gcctcggact cacgccgtgg
    22861 gtcgcgcacc agcgtgtcgg cgaacccctg gggcccgatc tggtccaacg tcttcaggta
    22921 gggcacgagg accgcgtcgc ggtagagcgg aggcagcgtg gcccgcgccg cctcgagccg
    22981 gccgcgcagc tggtgatagt cggtgggctc tggagggccc gggtccgtgt cctgcgccgc
    23041 gagcgccact tcgcggatgc aggcaggcag gttccggatg tccacggccg gcgccgttgc
    23101 accggagcct cgcgctgaag ccttcgcggc aggtgactcc tccaggaggg ccgtctccga
    23161 cggacgcccc cgaacacgtt tcgcggcgct gcgcggcagg gttccccctc cccgccggac
    23221 ct
//
