LOCUS       NZ_CP034669            26718 bp    DNA     circular CON 19-MAY-2024
DEFINITION  Corallococcus coralloides strain B035 chromosome, complete genome.
ACCESSION   NZ_CP034669
VERSION     NZ_CP034669.1
KEYWORDS    RefSeq.
SOURCE      Corallococcus coralloides
  ORGANISM  Corallococcus coralloides
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Corallococcus.
REFERENCE   1  (bases 1 to 9587888)
  AUTHORS   Bouhired,S.M., Rupp,O., Blom,J., Schaeberle,T.F., Kehraus,S.,
            Schiefer,A., Pfarr,K., Goesmann,A., Hoerauf,A. and Koenig,G.M.
  TITLE     Complete Genome Sequence of the Corallopyronin A producing
            Myxobacterium Corallococcus coralloides B035
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9587888)
  AUTHORS   Bouhired,S.M., Rupp,O., Blom,J., Schaeberle,T.F., Kehraus,S.,
            Schiefer,A., Pfarr,K., Goesmann,A., Hoerauf,A. and Koenig,G.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2018) Institute for Pharmaceutical Biology,
            University of Bonn, Nussallee 6, Bonn, NRW 53123, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 20-SEP-2017
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 350.5x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004104415.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:23:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,767
            CDSs (total)                      :: 7,695
            Genes (coding)                    :: 7,616
            CDSs (with protein)               :: 7,616
            Genes (RNA)                       :: 72
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 30 of 79
            Pseudo Genes (incomplete)         :: 55 of 79
            Pseudo Genes (internal stop)      :: 4 of 79
            Pseudo Genes (multiple problems)  :: 10 of 79
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:35:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5540041
            Orig. end                         :: 5566759
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034669.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Prof. Gabriele M. Koenig,
            Institute for Pharmaceutical Biology, University of Bonn.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26718
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="26"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..26718
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26718
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16718](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16718
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    complement(492..506)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     misc_feature    719..734
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.6"
                     /tool="antismash"
     gene            956..1078
                     /locus_tag="EJ065_RS40710"
                     /old_locus_tag="EJ065_4374"
     CDS             956..1078
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS40710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EJ065_4374"
                     /product="hypothetical protein"
                     /protein_id="WP_276320199.1"
                     /transl_table=11
                     /translation="MGEKSRALHRPMMRLKKEGRVRSAGERNATRYFPMGKKAA"
     gene            complement(1082..2464)
                     /locus_tag="EJ065_RS22070"
                     /old_locus_tag="EJ065_4375"
     CDS             complement(1082..2464)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020478325.1"
                     /locus_tag="EJ065_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4375"
                     /product="IS66 family transposase"
                     /protein_id="WP_128796354.1"
                     /transl_table=11
                     /translation="MAEVDPKDARIAELERQVEELTRLVQELREQLRRNSGNSNRPPSS
                     DTPGQKAERRRPSGSGRKRGGQPGHEGLTRALVAEEKVSEFKHLFPAACENCWAPLSTE
                     GGTRERHYQSVELPPLKAHVTQWVRHGVECPRCQHETWASTAPIPSTPFGPRLSAVVGL
                     LTGVYHLSRRSAVRLLGDVLGIDMSLGAVSAVEARVSEAVKCAVDEAWERVLLAPVKHT
                     DGTGWLEAGAARTLWTIATSVATVFKILTDGKSQTLAPLFGSKLGVLVSDRATALNFWA
                     MEKRQVCWAHLLRKAVSFSERDGPAGTIGRELLDYIGILFDYWGRLRSGELQRDALREL
                     MAPVRTHVEALLERAVAEGLPHVSGSCEDILAHRAALWTFVDRDDVEPTNNHAERELRA
                     FVLWRKRSFGTQSTRGNLFAERVMTVAHTARKQEKNVLEFLTDCGTAARTGAPPPSLFA
                     AP"
     gene            2570..2800
                     /locus_tag="EJ065_RS22075"
                     /old_locus_tag="EJ065_4376"
     CDS             2570..2800
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EJ065_4376"
                     /product="hypothetical protein"
                     /protein_id="WP_205694605.1"
                     /transl_table=11
                     /translation="MREPSVTVAYDVDERAAAAQRARAFKEAAKRGDLIGLAHMPFPGL
                     GRLSAEGKGYRWIPLNYSSGQRWEGTKATAE"
     misc_feature    2581..2599
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.7"
                     /tool="antismash"
     gene            2936..3169
                     /locus_tag="EJ065_RS22080"
                     /old_locus_tag="EJ065_4377"
     CDS             2936..3169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397409.1"
                     /locus_tag="EJ065_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4377"
                     /product="hypothetical protein"
                     /protein_id="WP_128797611.1"
                     /transl_table=11
                     /translation="MRYTRKNISELLDTVQGSPDVMGFWTSNFAGSAFTLVPSPGGMIW
                     QDVYAPSRQICEDGIPYGTEDGMNNHCGGTGY"
     misc_feature    2966..2968
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            3380..4330
                     /locus_tag="EJ065_RS22085"
                     /old_locus_tag="EJ065_4378"
     CDS             3380..4330
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ065_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EJ065_4378"
                     /product="hypothetical protein"
                     /protein_id="WP_128797612.1"
                     /transl_table=11
                     /translation="MALLACMWAVNQLTSDWKALLNKETQLLKLRSGVGVFFSANTHPL
                     ESFTSVALSSRGKGGGGSIDWGFYSVELKSPTRTVAVSGSNDRDEALELAQALSRFLGV
                     DLSVDGGHARPADARLEADPLERDQASPSLPPGSRIRVRHSAQGLVLQLPGCGWRPLFV
                     MKAGIALVIAVGGPTVFGLAWVRTFGLRQLTSAEPLIALAVFLSLGGLLLWSVIREVNR
                     GWSLAASSRGIEHSRTGGGKPREVTRLPASQIEDIDLRETEEKLFRSLTVVIEHKKGFV
                     RIGAGLSREELEWTETMLRRALATRGCQGRGDAEA"
     tRNA            complement(4704..4777)
                     /anticodon=(pos:complement(5544782..5544784),aa:Arg,
                     seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EJ065_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EJ065_4379"
                     /product="tRNA-Arg"
     gene            complement(4704..4777)
                     /locus_tag="EJ065_RS22095"
                     /old_locus_tag="EJ065_4379"
     gene            5045..6097
                     /locus_tag="EJ065_RS22100"
                     /old_locus_tag="EJ065_4380"
     CDS             5045..6097
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014396935.1"
                     /locus_tag="EJ065_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4380"
                     /product="hypothetical protein"
                     /protein_id="WP_205694606.1"
                     /transl_table=11
                     /translation="MATRLGVTLLLLVLLNACATPRVIRLDTGQGAPLEFRPSSSSNPS
                     VKVDTEAFEEALAQLVLDVPLTLRAPQQVLLVRASHPGTRADSRWQRLMRKSFGGLCDP
                     GQRRDHCLSLLDDGIGLGEWDKLGVALGLSLEPLKESIARAVEKTLAPQLFYTVIATGL
                     ITWAVLAANPEPVFTKAAAIVSAVLLIYLGVETFLEVVDASRELKRATDRATTWIELDQ
                     AGQRFANRVGPEVARGWPRGCRCCLATWRLRQPGHHGSAGPGKNWHHIVEQTPGNVARF
                     GPHALHNTENVISLEGGLHTQVSAFYSRRNLRVTGSRDLTVRQWLRTQSYEAQRAFGLQ
                     AIANIRNGVW"
     misc_feature    5267..5269
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6097..6447
                     /locus_tag="EJ065_RS22105"
     CDS             6097..6447
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020479166.1"
                     /locus_tag="EJ065_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2019 domain-containing protein"
                     /protein_id="WP_128797613.1"
                     /transl_table=11
                     /translation="MKLEELVEQFARQVQAETEAGWLGDAKAANRHVDQYLAVFDKLRA
                     RGDTGRDALAALFRHPRMDVRVAAAAFLLRHRTEEAKAVLEEAAKGTGMVPFEAQQALK
                     RWEDGTWALDPE"
     gene            6620..8209
                     /locus_tag="EJ065_RS22110"
                     /old_locus_tag="EJ065_4382"
     CDS             6620..8209
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397417.1"
                     /locus_tag="EJ065_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4382"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_128797614.1"
                     /transl_table=11
                     /translation="MLDRPMYLKPDVAIEPLFNQWYVWWYLISPATAPLFVSRLHLKLM
                     QSFVANPDVHVAALQNPALMGGPFINHPVSRVNEVKALLDRTTREQADMLAYTKAVSDL
                     EQLLASSKGESLEPLYAKVPDMLRGFVELHYDLAHRANARIMEPLLYRSSLYKESAQSI
                     SLMRVSGDARKYVFSTPRLEGDSPLWLQVPYRHEGIDALFRMRHTPGSPGQVAEMLGVP
                     SSAAEAFADLFTETAPRKPEPYTGPGVRVRYFGHACVLMETREVSVLTDPVISYEFPTD
                     QRRFTHADLPEKIDYVLITHGHADHLMMETLLQLRHRIGTIVVPRSNAYSLADPSLRLV
                     LEKTGFKNVIEIDDLQEIQIPGGSLMGIPFIGEHSDLAVQAKTAHLVRLAGRSLLMAAD
                     SNALEPRMYQHLSELVGPLDALYLGMECEGGPMSWMYGPLLSQPLPRKMDQSRRLNGSD
                     SARATEILNHLNPKEVFIYAMGQEPWLRHVMVLQYDETAPQMIESNKFIEVCKGRGIPA
                     ARPFLSMEQILE"
     gene            complement(8231..9904)
                     /locus_tag="EJ065_RS22115"
                     /old_locus_tag="EJ065_4383"
     CDS             complement(8231..9904)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020846.4"
                     /locus_tag="EJ065_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4383"
                     /product="S53 family peptidase"
                     /protein_id="WP_128797615.1"
                     /transl_table=11
                     /translation="MARIPLTQSARVSPVSLHPPLRSRSATGTVDVTLLLRHGAPLPTV
                     EELCANPPRRPLTHDEFEAKYGTNPKHLAAVRRFAKSHGLTITSERRDRGYVTLQGSTA
                     AIRKAFEVDLRRYTHGKSSYLTHTKPVHLPRALQGVAEWVLGLDTRPLVTHNAAALPIP
                     EAMAKQAGLRTYTAPQVASLYRYPRNEGEGQCVGIIELAGGYKPSDLEAYLKSVGVERT
                     APVVNVGPNKAGRLNTASNAEVTMDVELVASLCPAARVVVYNAASKDYSLRDYHRVLAE
                     AISDRENRPSVLTTSWSFYEGSLIQQGEELAFERLFIEAALLGITVCAASGDLGSQVPV
                     NARSPTGAITLAATSYPAASALVLGCGGTTLEAVGDGLHHERVWNRLGEAMSMGPSSTA
                     AGASSGGVSTMNALPLYQQGMGVPDRVQSSWKNGVFEVSRGTGRGVPDVAANADLHTGY
                     QIVFKGQQGVAAGTSAAAPMWAGLIVRLNEALGERVGFLHPRLYALVTEGQPVVRRITH
                     GGNGAYFASDATLWNACTGLGTPDGEALLTGLRRLQRRKH"
     aSDomain        10001..10294
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EJ065_RS22120_Goadsporin_CD_RRE.1"
                     /evalue="8.70E-20"
                     /identifier="RREFam013.1"
                     /label="EJ065_RS22120"
                     /locus_tag="EJ065_RS22120"
                     /protein_end="98"
                     /protein_start="0"
                     /score="61.6"
                     /tool="antismash"
                     /translation="MDRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVANVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLG"
     gene            10001..12193
                     /locus_tag="EJ065_RS22120"
                     /old_locus_tag="EJ065_4384"
     CDS             10001..12193
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002613718.1"
                     /locus_tag="EJ065_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4384"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_128797616.1"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.4e-17,
                     bitscore: 61.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 4.9e-23,
                     bitscore: 79.8, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 2.1e-20, bitscore:
                     71.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 2.2e-87, bitscore: 292.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLD
                     GERTVANVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWESLGVGAATA
                     AGRLLDVSVSVHAVDGEDGEGLAEALRDTGLDVRDAADRRVLLVDDYLSQEALALAQEA
                     RSVGAAFLPLKVSGTACHAGPVVDSGERACWTCLTARLLDNRPIEKYLARKGTPPRAIR
                     PPRTGLPTTAKAGLSFAATLVARWVVDGPGGPGQTRLWTLDFASWKLESHAVARRPQCP
                     DCGDPQWLEARAKKPLELASRSKRFTDDGGHRVLTPEQTWERHRHLISPVTGVVSDLRA
                     VPGDAPLGHIQSAVFRVCPWTDAPASDDFHRVASGKGRTEAQARAGALCEALERYSAVF
                     QGDEPRVHATASQLGAQAVHPDALQHFSAAQFQARPEIASRDMRTAVPRPYADQPMDWS
                     PAYSLTHGVHKYVPTAFAYLFAPPPPSGDGPFCFFSSNGNAAGNCVEEAILQGFLELVE
                     RDAVALWWYNRLRRPRVDLRSFDEPWFSSVSAHYQSLGLTLSVLDLTHDLGIPVFAALV
                     WSPERGRAWAGCGCHFDAKLAVQRALTEVAQCYDPKDVAPSPWDASAHGDVSWLFPNDL
                     VPARGRADFPRVWHNDLRDDVRECVARAASVGLETLVVEQSRPDVGVSAVKVIVPGLRH
                     FWPRLGPGRLYDVPVRMGWLKAPKTEAQLNPVPFYF"
     aSDomain        10004..10237
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EJ065_RS22120_Cyanobactin_D_RRE.1"
                     /evalue="1.80E-25"
                     /identifier="RREFam007.1"
                     /label="EJ065_RS22120"
                     /locus_tag="EJ065_RS22120"
                     /protein_end="79"
                     /protein_start="1"
                     /score="79.8"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVANVIAALAGRASAPEVLYALSLLEERGHV"
     aSDomain        10004..10285
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EJ065_RS22120_NHLP_CD_RRE.1"
                     /evalue="7.80E-23"
                     /identifier="RREFam015.1"
                     /label="EJ065_RS22120"
                     /locus_tag="EJ065_RS22120"
                     /protein_end="95"
                     /protein_start="1"
                     /score="71.3"
                     /tool="antismash"
                     /translation="DRVLRIKPHLRAEVLDARRVFLVGERAQFLLEGELHASIVPLLDG
                     ERTVANVIAALAGRASAPEVLYALSLLEERGHVEEAHDVFDASVAGFWE"
     gene            12197..14149
                     /locus_tag="EJ065_RS22125"
                     /old_locus_tag="EJ065_4385"
     CDS             12197..14149
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="EJ065_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4385"
                     /product="radical SAM protein"
                     /protein_id="WP_128797617.1"
                     /sec_met_domain="PF04055 (E-value: 1.1e-10, bitscore: 40.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPPPDPKPRILLVQCGPDRRHVDRETEDFDPEHGLVKRATMTPL
                     ACATLAALTPDAFSVDIWDEELHGQLRADTELPDYDIVGVSVMYSALTYQARFLGGHFR
                     DRGATVVAGGPAISAAPEDYRGFFDALFVNEAERTWPRFLADWLGGEYAPEYRQLDKPS
                     LSESPLPRWDAIAADLPRYAWGSVQTTRGCPFDCSFCDVIYLYGRKQRHKPVERVLDEV
                     RSHAALGAEGVFFADDEFIGDAAYAKEVLAGLVPLNRALPRPLRFFTQVTMNLSRDAGL
                     LEGMADANFYTVVLGIESFDTGALKEAQKHQNVRADLVGDLLRIQAHGIGPRGSFIVGF
                     DHDTPAVFDSLHANIQRTHLPWVVVAPLQAPRGTKLWTRLRAEGRLATPRRAHAKDRGA
                     IVLNVMPLGMTRPQLLEGFRDLVERLSTWDAACERIRGFIAGIQRPPQVEEPHWPEAVT
                     DRFLREATTAWALTPSERHALGDTLAEVRRTAPAMLPRAVFFLARNQNERRRHERLFTD
                     FDAVLAAERQGDLVPDTQPVYVPPGFATAMRDVFPDLFVRLSRDLPDRRDVPEASRDVL
                     VDFVARWGEGFQALQPQHHEFLRELCDREVAARGGHPGTLEVSEEQALRTQARRTGLLE
                     ALLKDVRDELASWGP"
     gene            14153..15310
                     /locus_tag="EJ065_RS22130"
                     /old_locus_tag="EJ065_4386"
     CDS             14153..15310
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397426.1"
                     /locus_tag="EJ065_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4386"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_128797618.1"
                     /transl_table=11
                     /translation="MRDGLHIFDADRHVLEPLSLWAEQLEPGLRRHAPRPGRLPDETLE
                     ERLERLGPQGLLPVLPLPEVDGKPLWNHMPEKAWLAFSARSYAQLGRNELLQRPDVYLA
                     QMDRDGVDMAALFPTYALLLEGFSPLEPRVATAFASVYNTWLHGFCAHQPERLRGVGLI
                     SRHQPEAMVAEVRRVAGFGWRAVMVRPNPIGGRLLSDAAYEPFWSECEKRSLAVVLHGS
                     GHVYVPSAGADRFDTRFANHVCAHPMELMMGLLALLQGGVLERHPALRIGAMEAGCGWL
                     PYWAWRLDEEYRAVGAEVSATIRQLPSAYMRQHCFVSMEPDEPYLSDVVRHLPEDRVVF
                     GSDFPHLDHGEDVLGAMLSLRDVMTESRLRKVLWENPTRFYGVEP"
     misc_feature    complement(14181..14195)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.98"
                     /tool="antismash"
     gene            15321..16718
                     /locus_tag="EJ065_RS22135"
                     /old_locus_tag="EJ065_4387"
     CDS             15321..16718
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03605.1"
                     /locus_tag="EJ065_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4387"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_128797619.1"
                     /sec_met_domain="PF00881 (E-value: 5.3e-06, bitscore: 25.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSLAEGVALRCPDAEDARVEGPGRSLRLGPLAPGVRAVFESLA
                     DGGIHETEVPAAAGSDTTLAWYWLDLAGDGGLLSWTVEERGNLLLTLTPASASFLRHRA
                     TFDAAQPLQLSRFAHTRMAEGRAVLDCPTVHATAALHDRRVVSLLFDMARPTLLARLNQ
                     FNTGIESFTLRELVRLLAETGILVPNGLDVPASEETQTALKQWEPHDLLFHLRSRGWGH
                     QTRAGATYRFRGELPNPPALKPTVTEEVVELHRPDLEALRAGGDRSFTEVLEARRSLRG
                     RGAAPLTVKQLGELLYRAARVRDVRTTQDGEITDRPYPGAGAVYALELYPMVGECQGLA
                     PGAYHYDPLGHRLEKLSGPTPEFHALLDEARAPAEPFERPEVLMVVAARVPRLAWKYET
                     LAYSLVLQDTGALVQTLYLVSTAMGLRPYALGRSDPDFFQRVAGVDGFGEASVGAFAVS
                     GGEPPDR"
     gene            complement(16738..17151)
                     /locus_tag="EJ065_RS22140"
                     /old_locus_tag="EJ065_4388"
     CDS             complement(16738..17151)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03795"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03795.1"
                     /locus_tag="EJ065_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4388"
                     /product="BMA_0021/BMA_0022 family TOMM bacteriocin"
                     /protein_id="WP_158617723.1"
                     /sec_met_domain="TIGR03795 (E-value: 3.4e-22, bitscore:
                     77.5, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKKPESKAAPARARPVARKPTRGPEGKASVNDWQAVWMRAVAL
                     AWKEPEFEAALQKDPRQALKKRFDFDLPASIHLKVVPSSVKDAATDGTWKVNSAEVELH
                     LPKKPADVADHAVALSSLTDTHGRSHCCGSPCC"
     gene            complement(17153..21244)
                     /locus_tag="EJ065_RS22145"
                     /old_locus_tag="EJ065_4389"
     CDS             complement(17153..21244)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397429.1"
                     /locus_tag="EJ065_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4389"
                     /product="TOMM system kinase/cyclase fusion protein"
                     /protein_id="WP_240672395.1"
                     /sec_met_domain="Pkinase (E-value: 1.2e-49, bitscore:
                     167.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPQLLEAFQGRYELLSELGEGGFGRVYKARQVTTGQNVAVKLLR
                     LTDGATPESVERRSARFEREMKLCAQMHHPNIVRLIDSGRAQGGAVYSIFEFVPGKNLA
                     QVLADEGLLDPVEARHLMLQLLDALACAHAQNVVHRDLKPANIMVVPTGARRNALVLDF
                     GIGSVTDELTRTEAQPRITSTNESLGTPSYAAPEQLRGQAPTPRSDLYAWGLVFLECLT
                     GRRIFEGATVAEVIFQQLSSEPVPIPSAIAAHPLGKLLQRVTAKDPSQRTVSAEVLLRQ
                     LEAVDVSNLPRRPAPVRIQPAAPNAETATVELSSRTPNAVSTRSRRWAEGERRQLTVVC
                     CTLSATQTAPGPVDIEELDHVLGAQQEVCIEIARRYNGHIASALGDIVLFYFGYPAARE
                     DDARRAAQAALDMVAEVKRRGRAIEAERGTRVEIRVGLHTGLVVSREQRDPTLSGLGFV
                     VGTTPKLAFRLSTSAPSGAILLTGDTQQLVRKHFPLEPVPASPSELMPPGLETFALQGA
                     DATWSGADEALSLVGRSRELDLVLSRWEQARSGQGQGVLISGEPGIGKSRLMRELGDRL
                     GAEPHTWLEARCTEDSSGQAYAPVVDLLTRMLDPNRDLPPEGRLTGLEALLSGYSFELP
                     ETLPLFASLLSLPLPPERWAPLDVSPLKHRELTRNALLAFLAAMAERQPVVLALEDLHQ
                     ADPSTLELLKALVEEVSSSRLLALFSARPELEPPWAASAVTQVQLGALARAEVERLATA
                     AAGGPLSPEALEEIFTRTDGIPLFVEELVRTLRESGALVEREGRFALEASKAGPAVPGT
                     LRDLLVARLDRLGRAKETAQIASVLGRELTHELLRHVSPLTPEALEADLERLVGSGLLH
                     RKRRPKGPVYLFKHALVRDAAYDSMLKRYRQQMHAKTAEAMEAHFQEQVESRPDLLAHH
                     WAAANLKRKAILYAQKAAFAALVRSAYLEAILFARLGLSWLDAIDDPVERAQLELSLNG
                     VLAPALMSTQGWRSQDLRDVAERSLELLFTVGESPYAAPTLWVLSIFYHLGGDQRRVRG
                     LLDRLVALAQRSGDAGQEAVALTILSNIELLEGRLGEAKAKADRCLALFDPVAHRMHRI
                     LYGQDTRVGGESVLCRGKWLLGFPDQAKAHGEAAVAWGRELNHGTSIGLSFIYLLLIAQ
                     EHGDRTEALQLISQHSELSHRYGLLEQAAYVGILRAWAVKDLEAMRRGIALREAFGTEM
                     DQPAYYAMLAELELESGHVEAALASVERGRQRAQALGEAYHESKMLHVKGRVLLQRDGN
                     TALSAETCFRQAAEVAHAQGARMRELQAVTALARVLQASGRQEEARQRLQTVYSTFSEG
                     WGTPPVSEARALLDALGGER"
     gene            complement(21253..23046)
                     /locus_tag="EJ065_RS22150"
                     /old_locus_tag="EJ065_4390"
     CDS             complement(21253..23046)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397430.1"
                     /locus_tag="EJ065_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4390"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_128800512.1"
                     /transl_table=11
                     /translation="MLVYNPGQPDELSYPLGDVPITIGRADDQGICIPHRSLSRQHARI
                     EPSDGRFFVTDLQSKNGTFVNGVQIRRKELRPGDTLTLGELVFLLTHEAPPAVPAGPPG
                     SGPASSASDEPRPQLTRALTRVPLKTLVQAVSGSERSAEEAPSTATRARERMRILQEVA
                     KLLSVTDDLEALPGRVLDLAFQILHVERGAILLVDEGTGKLEPRVTKTAEGTAVRGPIY
                     SQNIVDFVLRRSVAALFSDAVNDPRLGAAESVIFSSIRASMCVPLKPRDEVLGVLYVDN
                     VSTPKSFSEDDLEFLVAFAGQAALALENARLYRRIEQETVQRMQLIMDAKLASLAALVG
                     GMAHELRNPLNFISNFAGLSVGLTEDLAGVLEPQRERLTADSVRDVDEALVCLRTNVQK
                     INEHGRRADALIQNMLQHARRTPGPREAVELNALVAESVALGQGGMRGEPLTVRLEAEY
                     DPAVGRLELSRADVGRVIINVVDNALYAMRQKRQAQGGTYVPVLKVRTLARPEGVEVRL
                     RDNGPGVPAESAGRIFDPFFTTKPPGQGTGLGLSLSHDIIVQGHQGTFRMETAPGEFTE
                     FVITLPRRGGRSSMERGSGTR"
     gene            complement(23105..23665)
                     /gene="cysC"
                     /locus_tag="EJ065_RS22155"
                     /old_locus_tag="EJ065_4391"
     CDS             complement(23105..23665)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397431.1"
                     /locus_tag="EJ065_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4391"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_120620808.1"
                     /transl_table=11
                     /translation="MQQRPGFILWFTGMSGAGKSTLSTAVARQLSPVQRVELLDGDEVR
                     TYLSRGLGFSRADREENVRRIGYVARVLARHEVGVITAAISPYKSSRDEVRALATQAGI
                     PFLECYVQASLDALIARDVKGLYKKALAGEIPHFTGVSDPYEPPESPEITVRSDAETVE
                     AGVERILDTLRDRGLLAPAASAA"
     gene            complement(23676..24941)
                     /locus_tag="EJ065_RS22160"
                     /old_locus_tag="EJ065_4392"
     CDS             complement(23676..24941)
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397432.1"
                     /locus_tag="EJ065_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4392"
                     /product="GTP-binding protein"
                     /protein_id="WP_128797621.1"
                     /transl_table=11
                     /translation="MELLRFATAGSVDDGKSTLIGRLLYDTKSILEDQLAAVERTSHAR
                     GDEYVNLALLLDGLKAEREQGITIDVAYRYFSTAQRKFIIADTPGHLQYTRNMVTGAST
                     ADLALILVDARKGVLEQTRRHAFIASLLRVPHLVLCVNKMDLVDYDQGVFDRIREEFRQ
                     FSMKLDVSDLSFIPISALGGDNVVTRSEKMPWYQGPTLLHHLENVHIASDRDLIHLRFP
                     VQGVIRPASAKKFHDYRAYSGQLLGGVMRPGDEVMVMPSGFTTRIKALELAGKPLKEAF
                     PPMSVNVSLEEELDISRGDMLCRPGNPPTASQDIDAMVCWLSDSTQLNSGSRLAIKHTT
                     RMARAMVKQLHYRLDVNTLHRDEQSPGLKLNEVGRVTLRTTVPLFFDEYRRNRSTGSFI
                     LVDEGTNATVGAGMINGPAVDR"
     gene            complement(24941..25846)
                     /gene="cysD"
                     /locus_tag="EJ065_RS22165"
                     /old_locus_tag="EJ065_4393"
     CDS             complement(24941..25846)
                     /EC_number="2.7.7.4"
                     /GO_function="GO:0004781 - sulfate adenylyltransferase
                     (ATP) activity [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="cysD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014397433.1"
                     /locus_tag="EJ065_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EJ065_4393"
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="WP_128797622.1"
                     /transl_table=11
                     /translation="MSYELSHLEALEAESIFIIREVAAELDRPVLLFSGGKDSAVMLHL
                     AVKAFWPAPLPFPLMHVDTGHNFPEVIQYRDERVAELGARLIVASVQEAIDAGKVTEEK
                     GPRASRNRLQTQPLLEAIEKNGFNAVFGGARRDEEKARAKERVYSFRDEFGQWDPKNQR
                     PELWALYNGRHRRGEHLRVFPLSNWTELDIWQYIGRENVALPSIYYTHRREVFRRDGML
                     MAWSPFMAMMPGETVTTETVRFRTVGDMTCTACVPSTASTVEQVISEVTASRVTERGAS
                     RADDKFSETAMEDRKREGYF"
ORIGIN
        1 tcggcgactt cgaggtcacc gtgctgtccg acggcaccgt tccccagacc gtgagccagg
       61 tggcgacggg cacgacgcca gggcgggtga aggagctgct ctcgcgcgac cacctggagg
      121 atccggtcga attgtccatc aacgccttcc tcatcaacac cggcaccgcg ttggtgctcg
      181 tggacacggg cgtggggagc ttcttcggcc ctggcgtggg aggccagctc cagcagagcc
      241 tccaggcggc gggctaccgt cccgagcaga tcgacgtggt gttgctgacg cacatccact
      301 ccgaccattc gggtgggctc atggccaaga tgagccgggc gttccccaac gccatcctcc
      361 gcgtgcacgc gcgagaggcg ggcttctggc tggggcgcga tgaccgggcg aagggaccgg
      421 tggacccgaa gttcttcgag gaggctcggg cgatggtggg gccgtaccag gacgcgggga
      481 agctgaaggc gttcggagat ggagacgcca tcgttccagg catccgggcc atgccgaccc
      541 cgggacatac gccggggcac agcgcctacg tcgtggagag ccgtggagcg cggctggtcc
      601 tgtggggcga cctgatgcac ttcggctcgg tgcagttgcg cggtaaccgt tcaggggtgg
      661 tgttgaggcc gtcgtcgggg tgtgcaaccc gtggtggatg cacacgagaa ccccagcgac
      721 gctggaagcg aagattgaaa gactggttcg cgagcacctg ctggcccagc aactcctggt
      781 gagggctgcg gtggagcgcg cgttctcagc gctgagcgtc tcgccaggcg tagcaacgca
      841 gcgcagaagg acgggagtcc ggcggccctc aagcgcggtc gccgacctcg cggagcgact
      901 gctcgaagcg gtacaggcgt gcccaggcga gacgatggct gtccttaccg ctcgcatggg
      961 cgagaagtct cgggcgctgc accggccgat gatgcgcctg aagaaggagg gccgtgtgcg
     1021 cagcgccggc gagcgaaacg cgacgcgcta cttcccaatg ggaaagaagg ccgcgtagcg
     1081 ctcagggcgc ggcgaagagg gagggcgggg gcgcccccgt ccgtgcggcg gtgccgcagt
     1141 ccgtcaggaa ttcgagcaca ttcttctcct gcttgcgggc ggtgtgcgcc accgtcatca
     1201 cccgctcggc gaagaggttc ccccgggtgc tctgcgtgcc gaagcttcgc ttgcgccaca
     1261 gcacgaaggc ccgcagctcg cgctcagcgt ggttgttggt gggctcgacg tcgtccctgt
     1321 cgacgaaagt ccacagcgcc gcccggtgcg cgaggatgtc ctcgcaggaa ccggagacat
     1381 gcggtagtcc ctctgccacc gcgcgctcga gcagggcttc cacgtgcgtg cgcaccgggg
     1441 ccatgagctc gcgcagcgcg tctcgctgca actcgccgct gcgcagtcgc ccccaatagt
     1501 cgaagaggat gccgatgtag tcgagcagct cgcgcccaat cgttccggcg ggcccgtctc
     1561 tctccgagaa ggaaacggcc ttcctcaaga ggtgggccca gcacacctgc cgcttctcca
     1621 tggcccagaa attcagcgcg gtggcgcggt cgctgacgag gacgccgagc ttcgagccga
     1681 agagcggcgc gagcgtctgc gacttgccgt ccgtcagaat cttgaagacg gtggccaccg
     1741 aggtggcgat ggtccacagc gtgcgcgccg ctccggcttc aagccaaccg gtgccgtccg
     1801 tgtgcttcac cggcgcaagc aacaccctct cccaggcctc gtccaccgcg cacttcaccg
     1861 cctcgctgac gcgcgcctcg acggcgctca ccgcccccag ggacatgtcg atgcccagca
     1921 catcccccag aagcctcacc gccgagcgcc gactcaggtg gtagacgccc gtcaaaaggc
     1981 caacgacggc cgacagccgc gggccgaagg gagtgctcgg aatcggcgcg gtgcttgccc
     2041 acgtctcatg ctggcacctg gggcactcca cgccatggcg cacccactgc gtgacgtggg
     2101 ccttgagcgg cggcagctcc accgactggt agtgccgctc ccgcgtgccg ccttcggttg
     2161 agaggggggc ccagcaattc tcacatgcgg ccgggaagag gtgcttgaac tcgctcacct
     2221 tctcctcggc aaccagcgcg cgtgtcagcc cttcgtgtcc aggctgaccc ccgcgcttgc
     2281 gcccgctccc gctcggcctg cgccgctcgg ccttctgccc cggcgtgtcg ctcgacggcg
     2341 gccgattcga attgcccgag ttgcgacgca actgctcccg caactcctgc accagtcgag
     2401 tcagctcctc gacttgacgc tcaagctccg cgatgcgcgc atccttgggg tcgacctctg
     2461 ccacgaaagg ccatgtccca tgtccccccc cgcgtctgcg agcgacaagc ctcccgccgg
     2521 ctgctggcct gctccttctt caaccgcccc tcccccctga acggttacgt tgcgcgagcc
     2581 ttcggtgacg gtcgcctacg acgtcgatga gcgcgcggcc gcggcgcagc gggcgcgtgc
     2641 attcaaggaa gcggcgaagc gcggcgatct gattggcctc gcgcacatgc ccttcccggg
     2701 tctgggccgg ctgagcgcgg agggcaaggg ctaccggtgg atcccgctca actacagctc
     2761 cggccagcgc tgggagggca cgaaggccac ggcggagtga gagggttccg tgccggccca
     2821 tgggtgccgg cacggcgatc ttcaagcgtg acttgccacc cggattgctc ccttccccac
     2881 cgcttaccta ggatttcgac cttcgccgcc tcccctcctc tcaaggaccc aagccatgcg
     2941 ttacacgcgc aagaacatct ccgagttact cgataccgtg cagggcagcc ccgacgtcat
     3001 gggcttctgg acttcaaact tcgctggctc cgccttcacc ctggtcccct cccccggagg
     3061 catgatctgg caggacgtct acgcgcccag ccgccagatc tgcgaggacg gcatcccgta
     3121 cggcaccgag gacggcatga acaatcactg cggcggcacc ggctactgaa cttctcccag
     3181 cgcgccccca tcgcatagcc tcgtccagat gcgatgcgga tcccatcggt gggctgcctt
     3241 cggccctcac ctgaccattg agcgcgacgt acctcgcttc gtgagagggg cgtgcagggt
     3301 tgcgctgatc gcggccctct ccttccccgg cgttgcgctc ttcgtacctt ccctctggag
     3361 cgcatggccg gcatgggcca tggcgctcct cgcctgcatg tgggccgtca accaactgac
     3421 gtccgactgg aaggcgctgc tcaacaagga aacacagctc ttgaagctgc ggtccggtgt
     3481 cggcgtgttc ttctccgcga acacgcaccc gcttgagtct tttacgtccg tggccctttc
     3541 ctcccgcgga aagggtgggg gaggctccat cgactgggga ttctactcag tggagttgaa
     3601 gtccccgaca cgaaccgtgg cggtgtcggg gagtaacgac cgggacgagg cgctggagct
     3661 cgcccaagcc ctctctcgtt tcctgggcgt tgatttgagt gtggacggcg ggcatgcgcg
     3721 ccccgcggat gcccgtctcg aagcagaccc acttgagcgc gatcaggcgt caccgtcact
     3781 ccccccaggc agtcgtatcc gggtccggca cagtgcgcag gggttggtgt tgcagctgcc
     3841 aggctgcggc tggaggcccc tgttcgtaat gaaggcgggc atcgcgcttg tcatcgcggt
     3901 aggtgggccc accgtcttcg ggctggcctg ggtgcgcacg ttcggcctcc gccagctcac
     3961 ctccgcggag ccgctgattg ccctcgccgt cttcctttcc ctgggaggac tcctgttgtg
     4021 gagtgtcatt cgagaggtca ataggggttg gtctctcgcc gcctcctcac gggggattga
     4081 gcattcgcgc accgggggcg ggaagccgag agaagtcaca cgactcccag cgtcgcagat
     4141 cgaggacatc gacctgcgtg agacggagga aaagctcttc cggagtttga ccgtcgtcat
     4201 cgagcacaag aagggcttcg tgcggatagg ggcggggttg tcccgagaag aactcgaatg
     4261 gacggagacc atgctgcgcc gagcgctggc aacccgcggg tgtcagggca gaggcgacgc
     4321 agaagcatga ttcacggagt gtcgcaggag tgccgccgca agaggtggca cgctcgcgcg
     4381 aggaggcgcg tgccccattc cgtcaagggt caccagggtc gcgcgtggca aggtctccgc
     4441 gagccaatcc ggaagggtcg gctcgggcat gggccgtcga aggcaccgtc gggaatcacg
     4501 tggccgttga gcctgcgcca gttttcgacc cgcatcccag gtggcggccc tggtgtctcg
     4561 atggtcatag cggatgcccc ggtaacgccg ggcgagaagg gccacgagcg catccggccc
     4621 atcggactcc caaggtcgcg gcgcctgccc gtccgccctc cccgtcccaa cagaatcccc
     4681 tgttggaacg agaggttgcg gagtgacccc gacaggaatc gaacctgtgg cctgcggttt
     4741 aggaaaccgc cgctctatcc aactgagcta cggggtcgga agtgcgggag ttatagcagg
     4801 gggctcggcg cacgcaacgg gtctgacacc cgggagggcg gctctgtcca cctcgcggcg
     4861 aagcccctgg tgccaccgga ctggagagac gtccaccgag ccgatgtcct gcgccacctt
     4921 cgagcagcgg ctggccgagg cgtacgtgcg gctgcgcgcc gtggagacct tcgttcaggg
     4981 gcttgtccgt ctctggggcg accttccagt agactggaac tctccacgag ctggaaggcg
     5041 tctcatggca actcgtctgg gcgtcacgct cctgctcctc gtcctgctca atgcgtgcgc
     5101 cacgccgcgt gtcatccgcc tcgacacggg gcagggcgcg cccctggagt tcaggccgtc
     5161 gtcctcctcg aacccgtccg tgaaggtgga cacggaagcc ttcgaggagg cgctggcgca
     5221 actggtgctg gatgtgcccc tgacgctccg tgctccgcag caggttttac tggtgcgcgc
     5281 ctcccaccca ggtactcgtg ctgacagccg atggcagcgc ttgatgcgca agagctttgg
     5341 cggcctctgc gatccgggcc agcgcaggga ccactgcctc tcccttcttg atgacgggat
     5401 aggcctgggc gagtgggaca agctgggcgt ggccttgggg ctgtcgctgg agcccctcaa
     5461 ggaaagcatc gctcgggcgg tcgagaagac cctggcgccc cagctcttct acacggtcat
     5521 cgccacgggc ctcatcacct gggccgtgct ggcggccaat cccgagccgg tgttcaccaa
     5581 ggcggcggcc atcgtctccg cggtcctgct catctatctg ggtgtggaga cgttcctgga
     5641 ggtggtggac gccagccggg agctgaagcg ggccaccgac cgggccacga cgtggattga
     5701 gctggatcag gccggtcagc gcttcgccaa cagggtggga ccggaggtgg cgcgtggctg
     5761 gcctcgcggc tgtcgatgct gcttggctac atggaggctg cggcagccgg ggcatcacgg
     5821 ctctgcggga cctggcaaga actggcacca catcgttgag cagacgcctg gcaatgtggc
     5881 tcggttcggg cctcatgccc tgcataacac cgagaacgtc atctctctgg aaggagggct
     5941 gcacacccag gtgagcgcct tctattcacg gaggaatctg agggtcaccg gctcgcgaga
     6001 tctcaccgtg aggcaatggc tgcgcactca gtcttacgag gcccagcgtg cattcggatt
     6061 gcaggcgatc gcgaacatca ggaacggagt ctggtgatga aactcgaaga actggttgag
     6121 caattcgccc gccaggtgca agcagagaca gaggccggct ggctgggaga tgccaaagcc
     6181 gccaacaggc acgtcgatca atacctcgca gtattcgata aactccgcgc ccggggagat
     6241 acaggacgcg atgcgcttgc cgctcttttc agacatccac gcatggatgt ccgcgttgca
     6301 gcggcggcgt tccttctccg ccaccgcacg gaggaggcca aggcagtgct ggaagaggcc
     6361 gcgaaaggca ctgggatggt gcccttcgag gcgcagcagg ccttgaagcg gtgggaggat
     6421 ggtacctggg ccttggaccc agaatgacct atgcgacaaa tcctggggcg gaggacgtca
     6481 agcgtgatcc gcggaccctg cttccgggcc tggccaggaa gtccgcacct tgaagtcagg
     6541 ccgggaatcg tcaaaattgg cggcccatcc ccgtgcgtcc gggccccacg gttccggcgg
     6601 acgccctcgc gagacctcca tgctcgaccg cccgatgtac ctgaagcctg atgtcgccat
     6661 cgagccgctg ttcaaccagt ggtacgtctg gtggtacctc atctcccccg ccacggcgcc
     6721 gctgttcgtc tcccgcctgc acctgaagtt gatgcagtcg ttcgtcgcga acccggacgt
     6781 gcacgtggcc gcgctgcaga acccggcgct gatgggcggc ccgttcatca accaccccgt
     6841 gtcgcgcgtg aacgaggtga aggcgctgct cgaccgcacc actcgcgagc aggcggacat
     6901 gctggcctac accaaggccg tgtcggacct ggagcagctg ctggccagct ccaagggcga
     6961 gtccctggag ccgctctacg ccaaggtgcc ggacatgctc cgcggcttcg tggagctgca
     7021 ctacgacctg gcccaccgcg ccaacgcccg catcatggag ccgctgctct accgcagcag
     7081 cctctacaag gaatccgcgc agagcatctc gctgatgcgc gtgtccggtg acgcgcgcaa
     7141 gtacgtcttc agcaccccgc gcctggaggg cgattcgccc ctgtggctcc aggtgcccta
     7201 ccggcacgag ggcatcgacg ccctcttccg catgcgccac accccgggca gccccggaca
     7261 ggtggcggag atgctgggcg tgccgtcctc cgccgcggag gccttcgcgg acctcttcac
     7321 ggagaccgcc ccgcgcaagc ccgagccgta caccggcccc ggcgtgcgcg tgcgctactt
     7381 cggccacgcg tgcgtgctga tggagacgcg cgaggtgtcc gtcctcaccg accccgtcat
     7441 cagctacgag ttccccacgg accagcggcg cttcacccac gcggacctgc cggagaagat
     7501 cgactacgtc ctgatcaccc acggccacgc ggaccacctg atgatggaga cgctgctcca
     7561 gctgcgtcac cgcatcggga ccatcgtcgt gccgcgctcg aacgcgtact cgctggcgga
     7621 cccctcgctg cgcctggtgc tggagaagac gggcttcaag aacgtcatcg agatcgacga
     7681 cctgcaggag attcaaatcc ccggcgggtc gctgatgggc atccccttca tcggcgagca
     7741 cagcgacctg gcggtgcagg cgaagacggc gcacctggtg cggctggccg gccgctcgct
     7801 gctgatggcc gcggactcca acgcgctgga gccgcgcatg taccagcacc tgtcggagct
     7861 ggtgggtccg ctggacgcgc tctacctggg catggagtgc gagggcggcc cgatgagctg
     7921 gatgtacggc ccgctgctca gccagcccct gccgcgcaag atggaccagt cgcggcggct
     7981 caacggctcc gacagcgccc gcgccacgga gatcctcaat cacctgaacc cgaaagaggt
     8041 cttcatctac gccatgggcc aggagccctg gctgcgccac gtgatggtgc tccagtacga
     8101 cgagaccgcg ccccagatga tcgaatccaa caagttcatc gaggtctgca agggccgcgg
     8161 catccccgcc gcccggccct tcctgagcat ggagcaaatc ctggaatagg ggcgcgcccc
     8221 cacccgggct tcagtgcttg cggcgctgga gcctgcgcag gcccgtgagc agcgcctcgc
     8281 cgtccggcgt acccaggccc gtgcacgcgt tccacagcgt cgcgtcgctg gcgaagtagg
     8341 cgccgttgcc gccgtgggtg atgcggcgga cgacgggctg tccctcggtg acgagcgcgt
     8401 acagccgggg gtggagaaag cccacgcgct cccccagcgc ctcgttgagg cggacgatga
     8461 gcccggccca catgggcgcc gcggcgctcg tgcccgcggc cacgccctgc tggcccttga
     8521 agacgatttg atagccggtg tgcaggtccg cgttcgccgc gacgtccggc acgccccggc
     8581 cggtgccgcg ggacacttcg aacacgccgt tcttccacga cgactgcacc cggtccggca
     8641 cgcccatgcc ctgctggtac agcggcagcg cgttcatggt gctgacgccg ccgctgctcg
     8701 cgcccgcggc cgtggagctg gggcccatgg acatcgcctc gcccaggcgg ttccacacgc
     8761 gctcgtggtg gaggccgtcc cccaccgcct ccagcgtggt gccgccgcag cccagcacca
     8821 gcgcgctcgc cgcgggatag ctcgtcgcgg ccagggtgat ggcgcccgtg ggcgagcggg
     8881 cattcaccgg cacctgcgag cccaggtcac cggacgcggc gcacacggtg atgcccagga
     8941 gcgccgcctc gatgaagagc cgctcgaagg ccagctcctc gccctgctgg atgagcgacc
     9001 cttcgtagaa ggaccagctg gtggtcagca ccgacggccg gttctcccgg tcgctgatgg
     9061 cctccgccag gacgcggtgg tagtcgcgca gcgagtagtc cttcgacgcc gcgttgtaga
     9121 cgacgacgcg cgcggcggga cacagcgagg ccaccagctc cacgtccatg gtgacctccg
     9181 cgttggaggc ggtgttgagg cgccccgcct tgttgggccc cacgttcacc accggcgccg
     9241 tgcgctccac ccccacggac ttcaggtacg cctccaggtc cgacggcttg tagccgcccg
     9301 ccagctcgat gatgcccacg cactggcctt ccccctcgtt gcgggggtag cggtagaggc
     9361 tggccacctg gggcgccgtg tacgtgcgca gcccggcctg cttcgccatc gcttcgggga
     9421 tgggcagggc cgccgcgttg tgggtgacga gcggccgcgt gtccaggccc aggacccact
     9481 ccgccacgcc ttgcagcgcg cgcggcaggt gcaccggctt cgtgtgggtc aggtaggaag
     9541 acttcccgtg ggtgtagcgc cgaaggtcca cctcgaaggc cttgcggatc gcggccgtgg
     9601 acccctggag cgtgacgtag ccccggtcgc gccgctcgga ggtgatggtg aggccatggc
     9661 tcttcgcgaa gcgccgcacg gcggccaggt gcttcgggtt cgtgccgtac ttcgcctcga
     9721 actcgtcgtg ggtgagcggg cggcgcggcg ggttcgcgca cagctcctcc accgtgggca
     9781 gcggcgcccc gtgacgcagc aacagggtga cgtccaccgt gcccgtggcg gagcggctcc
     9841 ggagcggggg gtggagggac accggagaca cacgcgcgct ctgcgtcagg gggatgcggg
     9901 ccatgcgcgg cgttctacca cgcggggtcc gggctcccgg aagccgggga cggatcgtat
     9961 ccacgagcgc gggcgaccgg gtaggctcgc ccgcctgccc atggaccgag tcctccgcat
    10021 caagccccac ctgcgcgccg aggtgctcga cgcgcggcgc gtgttcctcg tcggggagcg
    10081 cgcccagttc ctgctcgagg gggagctgca cgcgagcatc gtgcccctgc tggatggcga
    10141 gcgcaccgtg gcgaacgtca tcgccgcgct ggcgggacgg gcctccgcgc cggaggtgct
    10201 ctacgcgctg tcgctcctgg aggagcgcgg gcacgtggag gaggcgcacg acgtcttcga
    10261 cgccagcgtc gccggcttct gggagtcgct gggcgtgggc gcggccaccg cggccgggcg
    10321 gctgttggac gtgtccgtct ccgtgcacgc ggtggacggc gaggatggcg aagggctggc
    10381 ggaggcgcta cgcgacaccg gcctggacgt gcgcgacgcc gccgaccgcc gcgtgctgct
    10441 ggtggacgac tacctgtcgc aagaagcgct cgcgctcgcg caagaggccc ggagcgtggg
    10501 cgccgcgttc ctcccgctga aggtgtccgg caccgcgtgc cacgcgggcc ccgtggtgga
    10561 ctccggcgag cgcgcctgct ggacgtgcct cacggcgcgg ctgttggaca accgccccat
    10621 cgagaagtac ctcgcgcgca agggcacccc gccgcgcgcc atccgcccgc cgcgcacggg
    10681 cctgcccacc accgcgaagg cggggctgtc cttcgcggcg acgctcgtgg cccgctgggt
    10741 ggtggacggg cccggcggcc cgggacagac gcggctgtgg acgctggact tcgccagctg
    10801 gaagctggag tcgcacgccg tggcgcggcg cccgcaatgc ccggattgcg gcgacccgca
    10861 gtggctggag gcgcgcgcga agaagcccct ggagctggcc tcgcgctcca agcgcttcac
    10921 cgatgacgga ggccaccgcg tcctcacgcc ggagcagacc tgggagcgcc accgccacct
    10981 catcagcccg gtgacgggcg tggtgagcga cctgcgcgcg gtgccaggag atgcaccgct
    11041 gggccacatc cagtccgccg tcttccgcgt gtgcccgtgg acggacgcgc cggcctccga
    11101 cgacttccac cgcgtggcca gcggcaaggg ccgcacggag gcccaggccc gcgcgggcgc
    11161 gctgtgtgaa gccctggagc gctacagcgc ggtgttccag ggcgacgagc cccgcgtcca
    11221 cgccaccgcg tcccagctgg gcgcgcaggc cgtgcacccg gacgcgctcc agcacttcag
    11281 cgccgcgcag ttccaggccc ggcccgaaat cgcgagccgc gacatgcgca ccgcggtgcc
    11341 ccgtccgtac gcggatcaac ccatggactg gagccccgcg tattcgctca cgcacggggt
    11401 ccacaagtac gtgcccacgg cgttcgcgta cctcttcgcg cccccgcccc cgtctggaga
    11461 cgggccgttc tgcttcttca gctccaacgg gaacgccgcg ggcaactgcg tggaggaggc
    11521 catcctccag ggcttcctgg agctggtgga gcgcgatgcg gtggcgctct ggtggtacaa
    11581 ccgcctgcgc cgtccgcgcg tggacctgcg ctccttcgac gagccgtggt tctcgtccgt
    11641 gagcgcgcac taccaatcgc tcggcctcac gttgtcggtg ttggacctca cgcacgacct
    11701 gggcatcccg gtgttcgccg cgctcgtgtg gtcgccggag cgcggccggg cctgggccgg
    11761 gtgcggctgc cacttcgacg cgaagctcgc cgtgcagcgc gcgctcacgg aggtggccca
    11821 gtgctacgac ccgaaggacg tggccccgtc gccctgggac gccagcgcgc acggcgacgt
    11881 cagctggctc ttccccaacg acctggtccc cgcgcgcggc cgcgccgact tcccgcgcgt
    11941 gtggcacaac gacctgcggg acgacgtgcg cgagtgcgtg gcccgggccg cgagcgtggg
    12001 cctggagacg ctggtggtgg agcaatcacg gccggacgtg ggcgtctccg cggtgaaggt
    12061 catcgtcccg gggctgcgcc acttctggcc acggctgggc cccggacggc tgtatgacgt
    12121 ccccgtgcgg atggggtggc tgaaggcccc gaagaccgaa gcgcagctca accccgtgcc
    12181 cttctacttc tgagcgatgg cgccgcctcc cgaccccaag cctcgcatcc tcctggtcca
    12241 gtgcggcccc gaccggcgcc acgtggaccg ggagacggag gacttcgacc ccgagcacgg
    12301 cctggtgaag cgcgcgacga tgacgccgct ggcctgcgcg acgctcgcgg cgctcacgcc
    12361 ggacgccttc agcgtggaca tctgggacga ggagctgcac ggccagctgc gcgcggacac
    12421 ggagctgccg gactacgaca tcgtcggcgt gtcggtgatg tactccgccc tcacctacca
    12481 ggcgcgcttc ctgggcggcc acttccgcga ccggggcgcc accgtggtcg cgggcggccc
    12541 cgccatctcc gccgcgccgg aggactaccg gggcttcttc gacgccctct tcgtcaacga
    12601 ggcggagcgc acctggccgc gcttcctcgc ggactggctc gggggcgagt acgcgcccga
    12661 gtaccgccag ctcgacaagc cgtcgttgag cgagagcccc ctgccccgct gggacgccat
    12721 cgcggcggac ctcccgcgct acgcgtgggg ctccgtgcag accacgcgcg gctgtccgtt
    12781 cgactgctcc ttctgcgacg tcatctacct gtacggccgc aagcagcggc acaagccggt
    12841 ggagcgcgtg ctggacgagg tgcgctcgca cgcggcgctc ggagccgagg gcgtcttctt
    12901 cgcggacgac gagttcatcg gcgacgcggc gtacgcgaag gaggtgctcg cggggctggt
    12961 gcccctcaac cgcgccctgc cccgcccgct gcgcttcttc acccaggtga cgatgaacct
    13021 gagccgcgac gctggtctgc tggagggcat ggcggacgcg aacttctaca ccgtcgtcct
    13081 gggcatcgag tccttcgaca ccggcgcgct caaggaagcg cagaagcacc agaacgtgcg
    13141 cgcggacctc gtgggtgacc tcttgcgcat ccaggcgcac ggcatcgggc cccggggcag
    13201 cttcatcgtc gggttcgacc acgacacgcc cgcggtcttc gactcgctgc acgcgaacat
    13261 ccagcgcacg cacctgccct gggtggtggt ggcgccgctc caggccccgc gcggcacgaa
    13321 gctgtggacg cggctgcgcg cggagggccg gctcgccacg ccccgcaggg cgcacgcgaa
    13381 ggaccggggc gccatcgtgc tcaacgtgat gcccctgggc atgacgcggc cccagctgct
    13441 cgaaggcttc cgcgacctgg tggagcggct gtccacctgg gacgccgcct gcgagcgcat
    13501 ccggggcttc atcgccggca tccagcgccc gccccaggtg gaggagcccc actggccgga
    13561 ggccgtcacc gaccgcttcc tgcgcgaggc caccaccgcc tgggccctga cgccgtccga
    13621 gcgccacgcc ctgggggaca cgctcgcgga agtgcgccgc accgccccgg cgatgctgcc
    13681 gcgcgcggtg ttcttcctcg cgcgcaacca gaacgagcgc cgccgccatg agcgcctctt
    13741 cacggacttc gacgcggtgc tggccgccga gcgccagggg gacctcgtcc cggacacgca
    13801 gcccgtctac gtcccgccgg gcttcgccac cgcgatgcgc gacgtgttcc cggacctctt
    13861 cgtgcgcctg agccgcgacc tgccggaccg ccgcgacgtg ccggaggcct cacgcgacgt
    13921 gctggtggac ttcgtcgccc gctggggcga aggcttccag gcgctccagc cgcagcacca
    13981 cgaattcctg cgcgagctgt gcgaccgtga ggtggcggcg cgcggtggcc acccaggcac
    14041 gctggaggtc tccgaggagc aggccctgcg cacccaggcg cgccgcaccg gcctgctgga
    14101 agcactgctc aaggacgtgc gcgacgagct cgcgagctgg ggaccctgac gcatgcgcga
    14161 cggccttcac atcttcgacg cggaccggca cgtcctggag ccgctgagcc tgtgggcgga
    14221 gcagttggag cccggcctgc gccggcacgc gccccgcccg ggacgcctcc cggacgagac
    14281 gctggaggag cgcctggagc ggctggggcc ccagggcctc ctgcccgtgc tccccctgcc
    14341 ggaagtggac ggcaagccgc tgtggaacca catgccggag aaggcctggc tggcgttctc
    14401 cgcgcgctcc tacgcgcagc tggggcgcaa tgagctgctg cagcggccgg acgtgtacct
    14461 ggcccagatg gatcgcgacg gcgtggacat ggcggcgctc ttccccacct acgcgctgct
    14521 cctggagggc ttctcgcccc tggagccccg cgtcgccacc gcgttcgcgt ccgtctacaa
    14581 cacctggctg cacggcttct gcgcgcacca gccggagcgc ctgcgcggcg tggggctcat
    14641 cagccgccac cagccggagg ccatggtcgc cgaggtccgc cgcgtcgcgg gcttcggctg
    14701 gcgcgctgtc atggtgcgcc ccaaccccat cggcggccgc ctgctgtcgg acgccgccta
    14761 cgagcccttc tggtccgagt gcgagaagcg ctcactcgcg gtggtgctcc acggcagcgg
    14821 ccacgtctac gtgccctccg cgggcgcgga ccgcttcgac acccgcttcg ccaaccacgt
    14881 gtgcgcccac cccatggagc tgatgatggg gctgctcgcg ctcctccagg ggggcgtgct
    14941 ggagcggcac ccggccctgc gcatcggcgc catggaggcc ggctgcgggt ggctcccgta
    15001 ctgggcgtgg cgtctggatg aggaatatcg cgctgtaggt gccgaggtct ccgccaccat
    15061 ccgacagctc ccttcagcgt acatgcgcca gcactgcttc gtttccatgg aaccggacga
    15121 gccgtacctg tctgacgtgg tgcgccacct cccggaggac cgagtggtat tcggaagcga
    15181 tttcccgcat ctggaccacg gcgaggatgt gctgggtgcg atgctgtcct tgcgtgacgt
    15241 gatgaccgaa agtcgtctac gaaaggttct ctgggaaaac ccgactcggt tctacggtgt
    15301 ggaaccgtga ggccgcacga atgagattgt cgctcgccga aggtgtggcg ctgcgttgcc
    15361 ccgacgcgga ggacgcgcgc gtggagggcc ctggccgctc actgcggttg ggcccgctgg
    15421 cccccggtgt gcgcgccgtc ttcgagtcgc tcgcggacgg aggcatccac gagacggagg
    15481 tgccggccgc cgcgggctcg gacacgacgc tcgcgtggta ctggctggac ctggcggggg
    15541 acggcggcct gctgtcgtgg acggtggagg agcgcggcaa cctgctcctg acgctcacgc
    15601 ccgcgtccgc gtccttcctg cgccaccgcg ccacgttcga cgcggcccag ccgctgcagc
    15661 tgtcccgctt cgcgcacacg cgcatggcgg agggccgcgc ggtgctggac tgccccacgg
    15721 tgcacgccac cgcggcgctg catgaccggc gcgtggtgtc gctgctcttc gacatggccc
    15781 gccccacgct gctggcgcgg ctcaaccagt tcaacaccgg catcgagtcc ttcacgctgc
    15841 gcgagctggt gcgcctgctg gcggagacgg gaatcctggt gcccaacggg ctggacgtgc
    15901 cggcgtcgga ggagacgcag acggcgctca agcagtggga gccgcacgac ctgctcttcc
    15961 acctgcgctc gcgcggctgg ggccaccaga cgcgcgcggg ggccacctac cgcttccggg
    16021 gcgagctgcc caacccgccc gccctcaagc ccaccgtgac cgaggaggtc gtggagctgc
    16081 accggccgga cctggaggcg ctgcgcgcgg gcggcgaccg ctccttcacg gaggtgctgg
    16141 aggcccgccg cagcctgcga ggccggggcg ccgcaccgct caccgtgaag cagctgggcg
    16201 aactgctcta ccgcgccgcg cgcgtgcgcg acgtgcgcac cacgcaggac ggtgaaatca
    16261 ccgaccggcc ctacccgggc gcgggcgcgg tgtacgcgct ggagctctac cccatggtgg
    16321 gcgagtgcca gggcctggcc ccgggcgcct accactacga tccgctgggc caccggctgg
    16381 agaagctgag cggccccacg ccggagttcc acgcgctgtt ggatgaagcc cgcgcaccgg
    16441 cggagccctt cgagcggccg gaggtgctga tggtggtggc cgcgcgcgtg ccccggctcg
    16501 cgtggaagta cgagacgctg gcgtactcgc tggtgctgca ggacacggga gcgctggtgc
    16561 agacgctcta cctggtgtcc accgcgatgg ggctgcggcc ctacgcgctg ggccggagcg
    16621 atccggactt cttccagcgc gtggcgggcg tggacggctt cggcgaggcc agcgtgggcg
    16681 ccttcgcggt gtcgggaggc gagcctccgg accgctaaaa gcgcccttcg cggcgcttca
    16741 gcagcagggg ctgccgcagc agtgcgagcg gccgtgggtg tcggtgaggc tggagagcgc
    16801 cacggcgtgg tccgccacgt cggcgggctt cttcggcagg tgcagctcca cctccgcgct
    16861 gttcaccttc caggtcccgt ccgtcgccgc gtccttcacg ctggagggga cgaccttcag
    16921 gtggatgctg gcgggcaggt cgaagtcgaa gcgcttcttg agcgcctggc gggggtcctt
    16981 ctggagggcc gcctcgaact cgggctcctt ccacgccagc gcgacggcgc gcatccacac
    17041 ggcctgccag tcattcaccg aggccttgcc ctcggggccc cgcgtgggct tgcgcgccac
    17101 cggacgggca cgtgcgggcg cggccttcga ctccggcttc ttcttgctca tgtcagcgtt
    17161 ctcctcccag cgcatccaac aacgcgcggg cctccgagac gggcggtgtc ccccatcctt
    17221 cggagaacgt actgtagacc gtttgcagcc gttgccgggc ttcttcctgt cgcccggatg
    17281 cctgaagcac ccgcgccagg gcggtgacgg cctgcagctc ccgcatccgc gcgccctgtg
    17341 cgtgtgccac ctccgccgcc tgccggaagc acgtctccgc ggagagtgca gtgtttccat
    17401 cccgctgcag cagcacccgg cccttgacgt gcagcatctt ggactcgtgg taggcctcgc
    17461 ccagggcctg cgcgcgctgc cggccgcgct ccacggaggc gagcgccgcc tccacgtggc
    17521 ccgattccag ctccagctcc gcgagcatgg cgtagtacgc cggctggtcc atctccgtgc
    17581 cgaacgcctc gcgcagcgcg atgccgcgcc gcatcgcctc caggtccttc acggcccagg
    17641 cgcgcaggat gcccacgtag gcggcctgct ccagcaggcc gtagcggtgg gacagctccg
    17701 agtgctggga gatgagctgg agcgcctccg tccggtcgcc gtgctcctgg gcaatcagca
    17761 gcaggtagat gaacgacagg ccaatgctgg tgccgtggtt cagctcgcgg ccccacgcca
    17821 ccgcggcctc gccgtgcgcc ttcgcctggt ccgggaagcc cagcagccac ttcccccggc
    17881 acagcacgga ctcgccgccc acgcgcgtgt cctggccgta gaggatgcgg tgcatccggt
    17941 gcgcgacggg gtcgaacagc gccaggcacc ggtccgcctt cgccttcgcc tcgcccaggc
    18001 ggccttccag cagctcgatg ttggagagga tggtgagcgc caccgcctcc tggcccgcgt
    18061 ccccgcttcg ctgcgccagc gcgaccagcc tgtccagcag tccgcgcacc cggcgctgat
    18121 cacctcccag gtggtagaag atggagagga cccacagcgt cggggccgcg taggggctct
    18181 cccccaccgt gaagagcagc tccagcgagc gctcggccac gtcgcgcagg tcctgggagc
    18241 gccagccctg cgtggacatc agcgccggcg cgagcacgcc gttgaggctc agctccagct
    18301 gcgcgcgctc caccgggtcg tcgatggcgt ccagccacga cagccccagc cgggcgaaga
    18361 ggatggcctc caggtaggcg gagcgcacca gcgcggcgaa cgcggccttc tgcgcgtaga
    18421 ggatggcctt gcgcttcagg ttcgcggcgg cccagtggtg cgcgagcaga tccggccgcg
    18481 actccacctg ctcctggaag tgcgcctcca tcgcctccgc cgtcttcgcg tgcatctgct
    18541 ggcggtaccg cttgagcatg gagtcgtagg ccgcgtcccg caccagcgcg tgcttgaaga
    18601 ggtacacggg ccccttcggc cggcgcttgc ggtgcaggag ccccgagccc accagccgct
    18661 ccaggtccgc ctccagcgcc tcgggcgtca gggggctcac gtggcgcagc agctcatgcg
    18721 tcagctcgcg gcccagcacg gaggcgatct gcgcggtctc cttggcgcgg cccagccggt
    18781 ccaggcgggc gacgagcaag tcccgaagcg tgcccggcac cgcggggccc gccttgctgg
    18841 cctccagcgc gaagcggccc tcgcgctcca ccagcgcgcc ggactcgcgc agcgtgcgca
    18901 ccagctcctc gacgaatagc gggatgccgt ccgtgcgcgt gaaaatctcc tccagcgcct
    18961 ctggcgagag cgggcctccc gcggcggcgg tggccagccg ctccacctcc gcgcgagcca
    19021 gcgcgcccag ctgcacctgc gtcaccgccg acgcggccca gggcggctcc agctccggcc
    19081 gcgcgctgaa cagggcgagc aggcgcgacg aggacacctc ctccaccagc gccttgagca
    19141 gctccagcgt ggacgggtcc gcctggtgca ggtcctccag cgccagcacc acgggctgcc
    19201 gctccgccat cgcggcgagg aacgcgagca gcgcgttgcg cgtgagctcc cggtgcttca
    19261 agggcgacac gtccagcggc gcccagcgct ccggcggcag cggcagggac aagagcgacg
    19321 cgaacagggg cagcgtctcc ggcagctcga agctgtagcc ggacaggagc gcctccaggc
    19381 ccgtgagccg gccctccggc ggcaggtcgc ggttcgggtc cagcatccgc gtgagcaggt
    19441 ccaccacggg ggcatacgcc tggccggagc tgtcctccgt gcagcgcgcc tccagccacg
    19501 tgtggggctc cgcgcccagc cggtctccca gctcgcgcat gaggcgcgac ttgccgatgc
    19561 ccggctcgcc cgaaatcagc accccctgcc cctgccccga gcgcgcctgc tcccagcgcg
    19621 acagcaccag gtccagctcg cgcgagcggc ccaccagcga cagcgcttcg tcagcgccgc
    19681 tccacgtcgc gtccgcgccc tggagcgcga acgtctccag gcccgggggc atcagctcgc
    19741 tcggcgacgc gggcacgggc tccaacggga agtgcttgcg caccagctgc tgcgtgtcgc
    19801 ccgtgaggag gatggcgccc gaaggcgcgg aggtggacag ccggaaggcc agcttcggcg
    19861 tggtgcccac cacgaagccc aggcctgaga gcgtgggatc ccgctgctcg cgcgacacca
    19921 ccaggcccgt gtgcaggccc acgcggatct ccacccgcgt gccgcgctcg gcctcgatgg
    19981 cacggccgcg ccgcttcacc tccgccacca tgtccagcgc cgcctgcgcc gcgcgccgcg
    20041 cgtcgtcttc ccgcgccgcc ggatagccga agtagaagag gacgatgtcg cccagcgcgc
    20101 tggcgatgtg gccgttgtag cgccgggcga tctcgatgca gacctcctgc tgggcgccca
    20161 gcacgtgatc cagctcctcg atgtccaccg gccccggcgc cgtctgcgtg gcggacagcg
    20221 tgcagcacac caccgtgagc tgccggcgct caccctccgc ccaccggcgc gagcgcgtgg
    20281 acacggcgtt gggcgtgcgg ctggacagct ccaccgtcgc cgtctccgcg ttgggggccg
    20341 cgggctggat gcgcacgggc gcgggccggc gcggcaggtt ggacacgtcc accgcctcca
    20401 actggcgcag cagcacctcc gcggacacgg tgcgctggga cgggtccttc gcggtgacgc
    20461 gctggagcag cttgcccagc gggtgcgcgg cgatggccga cgggatgggc accggctccg
    20521 aggagagctg ctggaagatg acctccgcga cggtggcgcc ctcgaagatg cggcggccgg
    20581 tgaggcactc caggaacacc agcccccacg cgtacaggtc cgagcgcggc gtgggcgcct
    20641 gcccgcgaag ctgctccggc gccgcgtacg acggcgtgcc cagcgattca ttggtggacg
    20701 tgatgcgcgg ctgcgcctcc gtgcgcgtca gctcgtccgt cacggagccg atgccgaagt
    20761 ccagcaccag cgcgttgcgc cgggcgccgg tgggcacgac catgatgttc gcgggcttca
    20821 ggtcgcggtg caccacgttc tgcgcgtgcg cgcacgccag cgcgtccagc agctggagca
    20881 tcaggtggcg cgcctccacc ggatccagca ggccctcgtc cgcgagcacc tgcgccaggt
    20941 tcttccccgg cacgaactcg aagatggagt agacggcgcc gccctgcgcg cggcctgagt
    21001 cgatgagccg cacgatgttg gggtggtgca tctgcgcgca cagcttcatc tcgcgctcga
    21061 agcgcgcgct gcggcgctcc accgactccg gcgtcgcgcc gtccgtcagg cgcaggagct
    21121 tcaccgccac gttctggccg gtggtcacct ggcgggcctt gtagacgcgg ccgaagccgc
    21181 cctcgcccaa ctccgacagg agctcgtacc ggccctggaa ggcttccaac agctggggat
    21241 ccatggggtt cttcatcgcg ttcccgagcc tcgctccatt gatgaccgtc ccccccgcct
    21301 gggcagggtg atgacgaact ccgtgaactc acccggcgcc gtctccatgc ggaacgtgcc
    21361 ctggtgaccc tgcacgatga tgtcatggct gagtgacagc cccagccccg tcccctgccc
    21421 cggcggcttc gtggtgaaga aggggtcgaa gattcttccc gcactctccg cggggacgcc
    21481 cggcccgttg tcgcgcagcc ggacctccac cccctccgga cgcgcgaggg tgcggacctt
    21541 gagcaccggc acgtacgtgc ccccctgcgc ctggcgcttc tgacgcatgg cgtagagcgc
    21601 gttgtccacg acgttgatga tgacgcggcc cacgtccgcg cggctcagct ccaggcgtcc
    21661 cacggccggg tcgtactcgg cctccaggcg gacggtcagg ggctcgcccc gcatgccgcc
    21721 ctgtcccagc gcgacgctct ccgcgaccag cgcgttcagc tccaccgctt cgcgcgggcc
    21781 gggcgtgcgg cgcgcgtgct ggagcatgtt ctggatgagc gcgtccgcgc ggcggccgtg
    21841 ctcgttgatc ttctgtacgt tggtgcgcag gcacacgagc gcctcatcca cgtcgcgcac
    21901 ggagtccgcc gtcagccgct cgcgctgcgg ctccagcacg ccggccaggt cctcggtgag
    21961 gcccacggag aggcctgcga agttgctgat gaagttgagc gggttgcgca gctcgtgcgc
    22021 catgccgccc accagcgccg cgagcgaggc cagcttcgcg tccatgatga gctgcatgcg
    22081 ctgcaccgtc tcctgctcga tgcggcggta gagccgcgcg ttctccagcg cgagcgccgc
    22141 ctgccccgcg aacgcgacga ggaactccag gtcgtcctcc gagaagctct tgggcgtgga
    22201 gacgttgtcc acgtagagca cgcccagcac ctcgtcgcgg ggcttgagcg gcacgcacat
    22261 ggaggcgcgg atggagctga agatgacgga ctccgcggcg cccaggcggg gatcattcac
    22321 cgcgtcggag aagagcgccg ccacgctccg gcgcagcacg aagtccacga tgttctggct
    22381 gtagatgggc ccgcgcacgg ccgtgccctc ggccgtcttc gtcacgcgcg gctccagctt
    22441 cccggtgccc tcgtccacca gcaggatggc gccccgctcc acgtggagga tctggaacgc
    22501 caagtccagc accctgccgg gcagcgcctc caggtcgtcc gtgacggaca agagcttcgc
    22561 cacctcctgg aggatgcgca tccgctcgcg ggcgcgcgtg gccgtgctgg gggcctcctc
    22621 cgcggaccgc tccgagccgg acaccgcctg caccagcgtc ttcagcggca cgcgggtgag
    22681 cgcgcgcgtg agctggggac ggggctcgtc ggatgcgctg gatgccgggc cggagccggg
    22741 cgggcccgcg ggcacggccg gtggcgcttc gtgggtgagc aggaagacga gctcgcccag
    22801 ggtcagcgtg tcgccggggc gcagctcctt gcggcggatc tgcacgccgt tgacgaacgt
    22861 gccgttcttg ctctgcaggt cggtgacgaa gaagcgcccg tcggagggct cgatgcgggc
    22921 gtgctggcgc gacaggctgc ggtgggggat gcagatgccc tggtcgtccg cgcggccaat
    22981 ggtgatgggc acgtccccca gcgggtagga cagctcatcc ggttgccctg ggttgtagac
    23041 gagcatcggc acggcttgag accccctccc gggtcccaag cctagccgaa aagcgatggc
    23101 cggctcaggc ggcgctcgcg gccggagcca ggagccccct gtcgcgcagc gtgtcgagga
    23161 tgcgctccac ccccgcctcc accgtctccg cgtcggagcg gacggtgatt tccggggact
    23221 cgggcggctc gtacgggtcc gacacgccgg tgaagtgggg aatctccccg gccagggcct
    23281 tcttgtagag ccccttcacg tcgcgggcga tgagcgcgtc caggctggcc tggacgtagc
    23341 actccaggaa cgggatgccg gcctgggtgg ccagggcgcg cacctcgtcc cgggagctct
    23401 tgtacgggga gatcgcggcg gtgatgacgc ccacctcgtg cctggccagc acgcgcgcca
    23461 cgtagccgat gcgccggacg ttctcctcgc ggtccgcgcg gctgaagccc aggcctcggg
    23521 agaggtacgt gcgcacctcg tccccgtcca gcagctccac gcgctgcacg ggcgacagct
    23581 gccgtgccac cgcggtggac agcgtgctct tgcccgcgcc ggacatgcca gtgaaccaga
    23641 ggatgaagcc cggacgctgt tgcatcgcca ttcccctacc tgtccacggc ggggccgttg
    23701 atcatccccg cgcccacggt ggcgttggtg ccttcgtcca cgaggatgaa gctgccggtg
    23761 ctgcggttgc gccggtactc gtcgaagaac agcggcaccg tcgtgcgcag cgtcacccgg
    23821 cccacctcgt tgagcttcaa gccggggctc tgctcgtcgc ggtgcagggt gttgacgtcc
    23881 agccggtagt gcagctgctt caccatggcg cgcgccatgc gggtggtgtg cttgatggcc
    23941 agccgggagc cgctgttgag ctgcgtggag tccgacagcc agcacaccat cgcgtcgatg
    24001 tcctggctcg cggtgggcgg gttgcccggg cggcacagca tgtcgccgcg gctgatgtcc
    24061 agctcctcct ccagcgacac gttcaccgac atgggcggga acgcttcctt cagcggcttg
    24121 ccggccagct ccagcgcctt gatgcgcgtg gtgaagccgg acggcatcac catcacctcg
    24181 tcgcccgggc gcatcacgcc gcccaggagc tgcccggagt acgcgcggta gtcgtggaac
    24241 ttcttcgcgg acgccggccg gatgacgccc tgcacgggga agcgcaggtg gatgagatcc
    24301 cggtcggacg cgatgtgcac gttctccagg tggtgcagga gcgtggggcc ctggtaccag
    24361 ggcatcttct ccgagcgcgt caccacgttg tccccgccca gcgcggagat ggggatgaac
    24421 gacaggtcgg acacgtccag cttcatggag aactggcgga actcctcccg gatgcggtcg
    24481 aacacgccct ggtcgtagtc caccaggtcc atcttgttca cgcacagcac caggtgcggc
    24541 acgcgcaaca gcgacgcgat gaacgcgtgg cgccgcgtct gctccagcac gcccttgcgc
    24601 gcgtccacca ggatgagcgc caggtccgcc gtggacgcgc ccgtcaccat gttgcgcgtg
    24661 tactgcaggt gtccgggcgt gtccgcgatg atgaacttgc gctgcgccgt ggagaagtag
    24721 cggtacgcca cgtcgatggt gatgccctgc tcgcgctcgg ccttcaggcc gtccaaaagc
    24781 agcgccaggt tgacgtactc gtcaccccgg gcgtggctcg tgcgctccac cgcggcgagc
    24841 tggtcctcga ggatggactt cgtgtcgtac aagagccgcc cgatgagggt gctcttgccg
    24901 tcatccacgg agcccgcggt cgcgaatctc agcagttcca ctagaagtat ccctcgcgct
    24961 tgcggtcttc catcgccgtc tcagagaact tgtcgtccgc gcggctggcg ccacgctccg
    25021 tcacgcggga ggccgtcacc tccgagatga cctgctccac ggtggacgcg gtggacggca
    25081 cgcacgcggt gcacgtcatg tcgcccacgg tgcggaagcg caccgtctcc gtcgtcaccg
    25141 tctcgccggg catcatggcc atgaagggcg accaggccat cagcatcccg tcccggcgga
    25201 acacctcgcg ccggtgcgtg tagtagatgg acggcagcgc cacgttctcc cggccgatgt
    25261 actgccagat gtccagctcg gtccagttgg acagggggaa cacgcgcagg tgctcaccgc
    25321 ggcggtggcg gccgttgtag agcgcccaca gctccggccg ctggttcttc ggatcccact
    25381 ggccgaactc gtcgcggaag gaatacacgc gctccttcgc gcgggccttc tcctcgtcgc
    25441 gccgggcgcc gccgaagacg gcgttgaagc cgttcttctc gatggcctcc agcaggggct
    25501 gcgtctgcag gcggttgcgg gacgcgcgag gccccttctc ctccgtgacc ttgcccgcgt
    25561 cgatggcctc ctgcacggac gcgacgatga gccgcgcgcc cagctccgcc acccgttcat
    25621 cgcgatactg gatgacctcc gggaagttgt gccccgtgtc cacgtgcatc agcggaaacg
    25681 gcagcggtgc gggccagaag gccttcaccg ccaggtgcaa catcaccgcg gagtccttcc
    25741 caccggagaa gagcagcacc ggccggtcca gctccgccgc gacttcccgg atgatgaaga
    25801 tggactcggc ttccagcgcc tcaagatgtg aaagctcgta actcacggcc gggcaagcta
    25861 ccacaacccg tcccacgccc aaccgtggcc gtgaaggttt ccgcttccgc gagtgtgaga
    25921 cacggcgggg atgcgacatg ccggaggggg cggtgaaaca tcgccggagg acctgctggg
    25981 agggatgttt cacggcccca ctcccggtgc gtgccacggg cccccacgcg ccgtgcggga
    26041 ggggattttc gcgcgggggg cgcatggtat agacggccgc gccatggcaa gcgcatcccc
    26101 tcccgtcctc gaccgttggt tcccgtcccg caagccgctt ccggagccgc gcctgcgcct
    26161 gttctgcctg ccgttcgccg gcgggagcgc ggccatctac cagccctgga gcatggcgct
    26221 gcccacgggc gtggagctgt gcgcggtgca gctgcccggg cgcgagcggc gcctgatgga
    26281 gccggcgatg aagtccctgc cggcgctgat ggacgtgctg atgccggcgc tgacgccgct
    26341 gatggaccgg cccttcgcgc tgttcggcta cagcatgggg gcgcgcatcg gcctggaggt
    26401 ggcccggacg ctgaagcgcc agggcggccc gaagccgctg ggcttcatcg ccgcggcggc
    26461 gcccccgccg tcgcacaacg accgggagcc catccacacg ctggatgatg cgggcttcat
    26521 cgcgaagctg cgcgagtacg acggcacgcc agaggaggtc ctccagcaca aggagctgct
    26581 ggagctcatc ctccccacgc tgcgcgcgga cttcgcgctg gcctggtcgg agaacggcaa
    26641 ggacacggcc ccgctggaca tcccgctgtc cgtgtacgcg ggcaaggggg acaagcacgt
    26701 gggcctggac acgatgga
//
