LOCUS       NZ_RQJW01000015        27873 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces cyaneus strain CGMCC 4.1671 Scaffold13_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RQJW01000015
VERSION     NZ_RQJW01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces cyaneus
  ORGANISM  Streptomyces cyaneus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 258987)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Streptomyces sp. nov., a novel actinobacterium isolated from a karst
            cave sample
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 258987)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-NOV-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135 Xingang West Road, Guangzhou, Guangdong 510275,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-OCT-2018
            Assembly Method                   :: SPAdes v. 3.6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004028635.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 03:28:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,717
            CDSs (total)                      :: 8,635
            Genes (coding)                    :: 8,413
            CDSs (with protein)               :: 8,413
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 222
            CDSs (without protein)            :: 222
            Pseudo Genes (ambiguous residues) :: 0 of 222
            Pseudo Genes (frameshifted)       :: 77 of 222
            Pseudo Genes (incomplete)         :: 187 of 222
            Pseudo Genes (internal stop)      :: 12 of 222
            Pseudo Genes (multiple problems)  :: 50 of 222
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:58:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 20831
            Orig. end                         :: 48704
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RQJW01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27873
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..27873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-iii"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(244..744)
                     /locus_tag="EHO50_RS37015"
     CDS             complement(244..744)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676689.1"
                     /locus_tag="EHO50_RS37015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_128435666.1"
                     /sec_met_domain="Metallophos_2 (E-value: 7.5e-29, bitscore:
                     94.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLLMSDTHLPKRAKALPDPLLAELPGADVVFHAGDWVDAATLD
                     LLESRCARLVGVYGNNDGPDLRARLPEVAYVELGGLRFGMVHETGPAQGRETRCASRFP
                     DLDVLVFGHSHIPWDTTAPTGLRLLNPGSPTDRRRQPHCTYMTATVTEGRLTDVELHRL
                     PPR"
     gene            949..2931
                     /locus_tag="EHO50_RS37020"
     CDS             949..2931
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040483.1"
                     /locus_tag="EHO50_RS37020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_128435668.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.1e-33,
                     bitscore: 108.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVKVSVVVPVYNPGVYVEDCIASLLRQSLPPDAYEVIFVDDGST
                     DDTPARLDALAATDPRVRVVHQANSGWSGKPRNVGIAAARGEYVMFVDHDDHLGDEALE
                     RMYDYGVANGADVVVGKMAGKGRAVPVELFRRNHPRATVANAPLIDSLTPHKMFRRAFL
                     DDIGLRYPEGRRRLEDHVFVTEAYLRASNVSVLSDYVCYYHVRRDDASNAGFQRFDPGG
                     YFKNLREALDVVERYTEPGPLRDRLLRRWLRVEMVERLRGRRFLAMPGDYRRELFEEIH
                     QVVVERFGPGVAAGLQPTQQVVAALIVADRYDDVEAFAEWEAGIALTAAPEHVVWEDGT
                     LRVGFSAEYTAAGEPMTFVGGKPMAVADGEPTAVAADSARTPLDGPPGDLAAAIARVGV
                     DTVARFGKATADLLLRERSSAAQYFQPLEFTRQEVPAGDDGRVRLVLRATAAVDPATLT
                     LGGVWDAFVRVKLGGWTKECRLGPAPREGRPAPHAGVVGGHVVLPYWTAPHTNLALDVD
                     RATHRVGLGAVTPDDVTASGARLRALLPLHAPHHGTDVSLRLTSSGTTHDVPATLSPQG
                     SGALLQALLPLADLRGTTWRTALGTPGPRFLTLPFALRAGVGGVQVVQTSRPDPLRRLL
                     RRARRRLGTALGRTAARLRARARRG"
     gene            2936..3532
                     /gene="rfbC"
                     /locus_tag="EHO50_RS37025"
     CDS             2936..3532
                     /EC_number="5.1.3.13"
                     /GO_function="GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="rfbC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380310.1"
                     /locus_tag="EHO50_RS37025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="WP_128435670.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.2e-63,
                     bitscore: 207.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSLGIEGAWALEPKVFPDDRGSFHEWYRGAEFREATGYDLSLAQ
                     ANCSVSRWGVLRGVHFSDVPPGQAKYVTCLRGAVLDVVVDLRVGSPTFARWEALRLDDD
                     SHHAVFLAEGLGHAFMALTDEATVVYLCSTGYAPEREHGVHPLDPDLGIAWPEHIPPVL
                     SPKDAQAPSLAEAERAGLLPSYETCRAYYDQLRAP"
     gene            complement(3538..4335)
                     /locus_tag="EHO50_RS37030"
     CDS             complement(3538..4335)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057839.1"
                     /locus_tag="EHO50_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_128435672.1"
                     /transl_table=11
                     /translation="MKRHEFLRELHKVSGNRNYLEIGVNDGRSLRLSRVPTVAVDPAFK
                     VVTEIRCDVHLVKATSDDFFARDNPLIHLKGGRHPLRNLRRGRSPFGYWRRTVLDLSFI
                     DGMHLFEYALRDFINIERHSDWASVIVFDDMLPRNVDEAARDRHTGAWTGDVYKIAEIL
                     GRYRPDLVTVLVDTEPTGQLVVFGADPRSTVLRDRYDEIVAEYEVPDPQKVPETILDRA
                     GAVAPEALLGAGFWRPLTRARRLGVGRSRGWEALRTAVERFTG"
     gene            complement(4322..5203)
                     /gene="rfbD"
                     /locus_tag="EHO50_RS37035"
     CDS             complement(4322..5203)
                     /EC_number="1.1.1.133"
                     /GO_function="GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (47-154). E-value:
                     1.1e-07. Score: 23.1. Matches aSDomain:
                     nrpspksdomains_EHO50_RS37035_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500826.1"
                     /locus_tag="EHO50_RS37035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="WP_128435674.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-109,
                     bitscore: 357.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWLVTGAGGMLGRDLVEELLARGEQVAGLGHAALDITGADAVDR
                     ALAAYRPDLVVNCAAYTAVDDAEQDEERALRINGDGPGLLAHTCTAYEARLIHLSTDYV
                     FAGDARTPYAENHPTAPRTAYGRTKLAGERAVLDELPASSAIVRTAWLYGVHGRSFVRT
                     MIELEASRDTVDVVDDQRGQPTWTADVAATIADLGPRVGVDATGILHATNSGEATWYDL
                     AREVFQLLGADPDRVRPVTSEAFPRPAPRPAYSVLAQGRRQRLGLARARDWRTALHEAL
                     PRIRKETLRETP"
     aSDomain        complement(4742..5062)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EHO50_RS37035_NAD_binding_4.1"
                     /evalue="1.10E-07"
                     /label="EHO50_RS37035_NAD_binding_4.1"
                     /locus_tag="EHO50_RS37035"
                     /protein_end="154"
                     /protein_start="47"
                     /score="23.1"
                     /tool="antismash"
                     /translation="AAYRPDLVVNCAAYTAVDDAEQDEERALRINGDGPGLLAHTCTAY
                     EARLIHLSTDYVFAGDARTPYAENHPTAPRTAYGRTKLAGERAVLDELPASSAIVRTAW
                     LYG"
     CDS_motif       complement(5132..5194)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EHO50_RS37035_0001"
                     /evalue="6.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="EHO50_RS37035"
                     /protein_end="24"
                     /protein_start="3"
                     /score="9.2"
                     /tool="antismash"
                     /translation="LVTGAGGMLGRDLVEELLARG"
     gene            complement(5200..6198)
                     /gene="rfbB"
                     /locus_tag="EHO50_RS37040"
     CDS             complement(5200..6198)
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-185). E-value: 5.3e-20.
                     Score: 63.5. Matches aSDomain:
                     nrpspksdomains_EHO50_RS37040_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995663.1"
                     /locus_tag="EHO50_RS37040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="WP_128435676.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-19, bitscore:
                     62.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.2e-20,
                     bitscore: 65.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2e-19, bitscore:
                     63.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLLVTGAAGFIGSTYVRTLLARDAPNAPGAPETPRITVLDKLTY
                     AGTLDNLELGHPRLKFVRGDIRDAELVDKLMAEADQVVHFAAESHVDRSIAGADDFVLT
                     NVVGTHTLLDAALRYGVAPFVHISTDEVYGSVETGSATEEDPLRPSSPYSASKASSDLL
                     ALAYHRTHGLDVRVTRCSNNYGPHQFPEKVVPLFITNLLDGEQVPLYGEGLNVRDWLHV
                     DDHCHAVELVRTKGRPGEIYNIGGGTELSNKDLTALLLEACGADWDRVEHVEDRKGHDL
                     RYSVDWTKARTELGYRPRHDFAAGLAATVAWYRDHRAWWEPLKRRVGEEHG"
     aSDomain        complement(5644..6186)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EHO50_RS37040_NAD_binding_4.1"
                     /evalue="5.30E-20"
                     /label="EHO50_RS37040_NAD_binding_4.1"
                     /locus_tag="EHO50_RS37040"
                     /protein_end="185"
                     /protein_start="4"
                     /score="63.5"
                     /tool="antismash"
                     /translation="VTGAAGFIGSTYVRTLLARDAPNAPGAPETPRITVLDKLTYAGTL
                     DNLELGHPRLKFVRGDIRDAELVDKLMAEADQVVHFAAESHVDRSIAGADDFVLTNVVG
                     THTLLDAALRYGVAPFVHISTDEVYGSVETGSATEEDPLRPSSPYSASKASSDLLALAY
                     HRTHGLDVRVTRCSNNYG"
     gene            complement(6195..7262)
                     /locus_tag="EHO50_RS37045"
     CDS             complement(6195..7262)
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040494.1"
                     /locus_tag="EHO50_RS37045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="WP_128435678.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.5e-09, bitscore:
                     31.4, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLSGGAGTRLRPITHTSAKQLVPVANKAVLFYGLESIAAAG
                     ITDVGVIVGDTAAEIQDAVGDGSKFGLEITYIPQERPLGLAHAVLIARDYLADDDFVMY
                     LGDNFVVGGITDLVEEFRGNRPDAQILLTRVQDPRSFGVAELDDAGRVIGLEEKPEHPK
                     SDLALVGVYLFTPAIHDAVRAITPSWRGELEITHAIQHLIDARADVRCTVIKGYWKDTG
                     NVADMLEVNRTVLEGLARRIDGDVDDASETVGRVVVEEGARIVNSRIVGPAVVGTGTVV
                     EDSYVGPFTSIAENCRITDSELEFSIVLRDSWIDGVGRIESSLIGRHVEVTPAPSVPSA
                     HRLVLGDHSKVQIHT"
     gene            complement(7357..9813)
                     /locus_tag="EHO50_RS37050"
     CDS             complement(7357..9813)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995665.1"
                     /locus_tag="EHO50_RS37050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_128435681.1"
                     /transl_table=11
                     /translation="MANVVNEGAAGRRTRSLRAEDALKALAVEPDSPERLRRVLEQALV
                     FGGASFAAVYTPSEDGELLCLVESAGVPRTLYGLRDGYALAGPSPVADAHRTGLPLWLG
                     PAELADCAEARRVPSRDFHLAVLPLHGDDGGGCLAAVSESPGGFDAEDRACLQLIAEAV
                     AFPALPAAAEGGELPAGAFSLAMDTGRVEVGDDILELFGLRPDHFDGKVETLLGLTVPE
                     DLPSLMSVVEAGHMSIGDRELEFRVLQPSGPPKWLRLRGRLLPGGEGHPARLVGTVADT
                     STLRAEVTDVARVQRLAAALATAGTVRDVSHAVVTALRKPLHADRIALAELENDRLVVT
                     VLDPPQPESWPQLWRTEWRTEWPDAPVRAMPTLAAALREGRPQIWPAGTPLEPALADVG
                     PGGLAVLPLPAGGRMAGACLIGWDAPHDFGPDERALLTASAGLAGQALLRAHAVDAEHE
                     LVGMLQRQLLPRRLPRLPGAKAVARYLPTTAGLEVGGDWYDVIPLPDNHVALVIGDVQG
                     HSAAAATLMGQMRTALRAYAAEGHPPDVVVHHANRLLIDMETDLFATCAYVDVDLEEGT
                     AWCVRAGHLPPVLRHPDGSTEIAEAEGGPPLGVMREADFPMSPLRLQPGTVIALTTDGL
                     VESADADIDTGIDRLAHALARSDPAHLGLVADALLVGARRSDDVALLLLRYEGMAVRPL
                     RESWTVWRVPEAVGHARRFTRRTLRSWGLPAQDMDAVLLVVSELVTNALVHTDGRVRLD
                     LTLVNQRLRVAVADASPRTPVKPAGISWEATGGRGILLVEAMSAAWGTVPVSGGKQVWS
                     EVALGG"
     misc_feature    complement(9517..9519)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..12598
                     /gene="lanKC"
                     /locus_tag="EHO50_RS37055"
     CDS             10001..12598
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134770.1"
                     /locus_tag="EHO50_RS37055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_128435683.1"
                     /sec_met_domain="micKC (E-value: 2e-231, bitscore: 764.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2e-11, bitscore: 37.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.6e-08, bitscore:
                     26.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADRHFYETPERMSAGTPGTGLGYETARREVPEGWD
                     AARIGDWLTLTPLGADGAPVPGPAQGWKIHASATRGNAERVAAIVWDYCVPRRISFKFV
                     PSPHLLHLRNTKYAARDTSGKFVTIYPADEEQLHVVLRELGKLLEGFEGPYILTDLRWY
                     DGPLYVRYGAFARTFVVDERGSLVPAVVDGEGKRVPDRRAPSFQVPEWVTLPAFLEPHL
                     AARNTTTVGELPYRIEKALHFSNGGGVYSGTDTRDGRKVVLKEGRPHAGLAADGADAIS
                     RLEREKSALEQVAGTGVVPEVRDWFTLGDHRFLVMDFLQGRPLNSFFAERHPLLTPDPD
                     PKAVAEYTAWAVRIHGAVQRAVEAVHARGIVFNDLHVFNIMVGPDEESVSLLDFEAAAP
                     VEENGRQVVAHPGFFAPPDRTGADVDRYALACLRLALFLPVTTLFVVDRGKAAHLAEVI
                     IRQFPDVPREFLDEAVAEITRGTTAPAPSFVEPGEWPFSRDSMVKALLASATPERDDRL
                     FPGDITQFNDGGGLGLAHGAAGVLYALDAVGAERYEEGERWLLARTAPPPTGTPLGLYD
                     GLAGVAHVLDRLGHRQRALDLVERILAERWQNLASDLHGGLAGLGLVLGELARTTGESE
                     LLDRAAEAADILVRRLAQPLADSPKRRRAGLLRGASGPALFLLRQHERTGEPLLLKAAE
                     VALRRDLDCCMTHPTGSLEVDEGWRTLPYLGDGSAGIGMVLDDYLAHGADSEGEFERAR
                     AGILTAATSRFYVQPGLFQGRAGMILHLARTDTPGATRERLAEQIEGLGWFAMDYQGQL
                     AFPGHQMMRLSMDLSTGTAGCLLALGAALDTPATAHLPFLPPLGRPHIRGSAT"
     gene            12658..12774
                     /locus_tag="EHO50_RS37060"
     CDS             12658..12774
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="EHO50_RS37060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_128435685.1"
                     /transl_table=11
                     /translation="MALLDLQTMESDELTGGGGASTLSLLSCVSAASLTLCL"
     CDS_motif       12658..12720
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMESDELTGGGGAS"
                     /locus_tag="EHO50_RS37060_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12721..12774
                     /prepeptide="core"
                     /locus_tag="EHO50_RS37060_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="21.80"
                     /molecular_weight="1586.9"
                     /monoisotopic_mass="1585.9"
                     /core_sequence="TLSLLSCVSAASLTLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMESDELTGGGGAS"
                     /leader_location="[12657:12720](+)"
                     /alternative_weights="1605.0"
                     /alternative_weights="1623.0"
                     /alternative_weights="1641.0"
                     /alternative_weights="1659.0"
     misc_feature    12665..12685
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            12883..14574
                     /locus_tag="EHO50_RS37065"
     CDS             12883..14574
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655805.1"
                     /locus_tag="EHO50_RS37065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_128435687.1"
                     /transl_table=11
                     /translation="MTQAIRTLPGPLGPAPARCVVLCLVSTASTGVGLLLPAALGHTLD
                     LLLSQSPATRWVLYCTAIVVLLALLDACETVLGGTVDARTTAWLRRRLTGHVLTVGPRA
                     AARFGPGDLVARLVGNAAQAGTAPTARAALLAALAGPVGGVVALALIDPWLAAVLLAGA
                     PVLALLLRAFARDTRDCVTRYQQAQGRIAQALSEAVGGHRTIEAAGTADRETARILRPL
                     PELSDAGHRMWRVQGRAAGRSVAVAPLLQLGVVAVAGVLLARHRLTVGEVLAASRYAVL
                     ATGVGVLVGHLAGLARARAATARLDEVLAEPAPGYGERSLPPGPGRLELRGVTALRGGR
                     RVLDGVDLVVPGGTTLAVVGRSGAGKSLLAAIAGRLAEPDAGEVLLDGVPLRELTHDTL
                     RRAVGHAFERPALLGGTVEEEIGLALSSPAPDRVREAARTAHADDFVRRLPRGYATAVA
                     DAPRSGGESQRLGLARAFAHGGRLLILDDALSSLDTVTEARITAALVSSGPHTGTRLLI
                     AHRAATAARADAVAWLDGGRVRAVGRHEELWQIRDYRAVFADGEQP"
     misc_feature    complement(12907..12926)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.15"
                     /tool="antismash"
     gene            14571..16520
                     /locus_tag="EHO50_RS45920"
     CDS             14571..16520
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655806.1"
                     /locus_tag="EHO50_RS45920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_128435689.1"
                     /transl_table=11
                     /translation="MTEHVHRRGLRFLWDRWRVVARLAGWSVLETGQTFLTGFALARAL
                     DEGFLAGRPGIGLAWLGVAGLGVLVGAYGTVRVYGAVAALVEPLRDRLVARVVARGVRE
                     ADAGALSGLTQQVEIARDTFAGLVMVSRSFVFTSVGAVAGLVSLDPLLLLVVGPPLAAG
                     LGLFAATLRPLARRQEAFLVADEALADRLGTVCPGLRDITAAGAEERVAATTGICVDTE
                     LRAASSLARWGVLRVVSLALGGQLPIVLLLACAPWLLQHGVTAGALVGALAYVTQSLLP
                     ALRNLVHGLGTSGSRLAVVLRRLTRETSSLAGAATGAGIGAGSGAGSGAGAGAGAETGA
                     EAGTGAGAGPETGAGPGAAPPVLSLTSVTFAYGPDATPVIDDLDLTLAPGAHLAVVGPS
                     GIGKSTLAALVAGLLEPGRGTVRLCGHPVPGAEAAALRVLIPQEAYVFTGTLAENLGHL
                     RPDPVPEAELLAAAKAVGLLPLLEALGGPTATVDPAALSAGERQLVALTRAYLARAPLA
                     LLDEATCHLDPRAEERAERAFAQRPGGTLVVVAHRISSARRADRVLVMDGRHTAYGTHD
                     ELVRRSASYRALVGSWTPEPSEPALALRDPDRVDAIAGTGLTGDGGHVVAHGPVRQMQA
                     PRDLRHRGSLGGEG"
     gene            complement(<16443..17024)
                     /locus_tag="EHO50_RS37075"
                     /pseudo=""
     CDS             complement(<16443..17024)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="EHO50_RS37075"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGHAHFTKEPVQGESKGRAVIRVLLVHDACLVRSVLAEWLRREPD
                     LGVFDASWQSAPRRLRSVRPDVCAADLDCSDSYGIPPLGDLCGREAGRTPPRLLVLASA
                     HRPGLLKRAAEAGALGYVDKEGSPEQLVQGIRKVAEGERFVDDSLGFGFLKAAEMPLTR
                     RELSVLSLAAEGASVAEIAGSLHLSHGTVRN"
     misc_feature    complement(16518..16520)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17331..19481
                     /locus_tag="EHO50_RS37080"
     CDS             17331..19481
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117170.1"
                     /locus_tag="EHO50_RS37080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_128435694.1"
                     /transl_table=11
                     /translation="MVGVSDGQTSAQAPAAARTRVGRPLLSLALASMMDEVHAHSGAVY
                     LLAADEPVLEMAVMAGLPRAFAAPWERVGLSAPIPVAEAVRERRLVWVGGEEDMAARYP
                     RIAVVLPYPFALAALPVATGTTVYGAIFVTWPGSHSPELSEREQEHLNAACRRLAVRLE
                     RAMEDSRPPLPEPDLLAGPAFSGAAGTLGTVEAARMVSRLPYGLCSLDLHGRISFANPA
                     AAELIGVPANRLLGNQLWASVPWLNDPVYEDRYRAALMSQQTTSFVALRPPGDWLSFRM
                     YPSTTGLSVRISRARAVAEMGRSGPQPGDAPARLVTISQVLSLAGALTEAAGVQDVVQL
                     VADEIVPAVGSQALVVLGSRAGRLHVLGHRGYPDPQIVERFDGMPLTKQTPGTHALSTG
                     VPAFFESQEQLERLYPVRLATPDGFAAWAYLPLIASGRPVGTCVLAYAEPHAFPADERA
                     VLTSLGGLIAQALERAQLYDAKNQLAHGLQAALLPHSLPTLPGVEAAARYLPAMQGMEI
                     GGDFYDLVPTEEGLAAAVIGDVQGHNVTAAGLMGQIRTAVRAYTTVGQAPEEVMRSTNR
                     LLLDLGSDLFASCLYLRLDPEHGRAVMARAGHPPPLLRRPDGRVRVLDLAGGPLLGIDG
                     SPTYPTTEVELTPGCVLVLYTDGLIESPGVDIEDALADLGQVLTEAGERPLDELADLLV
                     QHAASVRERVDDVALLLLRARG"
     cand_cluster    17658..27873
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    17658..27873
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22657:22873](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      22658..22873
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            complement(20237..21580)
                     /locus_tag="EHO50_RS37085"
     CDS             complement(20237..21580)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500817.1"
                     /locus_tag="EHO50_RS37085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S1 family peptidase"
                     /protein_id="WP_128435697.1"
                     /transl_table=11
                     /translation="MSHKRIPKRKAAIAAGSVVALGAAAILLPNANASQDGASNDAAAP
                     KTLKAADASDLASQLSGLLGDAFAGSYYDAESQQLVVNVVPGDNNNVIVQAKKAGAKVR
                     EVENSLTELASGAQTLKSEATIPGTAWAVDPRTNKILVTADSTVTGDNWDQLESTVQSL
                     GSGMATIKKSAGTFKTFLSGGDAIFAGGSRCSAGFNVTAGDGTPAFLTAGHCGVAAEQW
                     SDAEGGQPIATVDQATFPGAGDFALVKYDDPATEAPSEVNLGDQTLAISQAADAEVGLQ
                     VLRMGSTTGLNDGQVTGLDATVNYPEGTVTGLIQTNVCAEPGDSGGSLFTQDGLAIGLT
                     SGGSGDCTVGGETFFQPVTTALEAVGATLGGDAAGGAGAGEEAGAGDEAGAGEEAGAGE
                     EAGAGEEAGAGEEVGGEEAGAGEEVGNGNADGTGNGLGEIVGNGVGVN"
     gene            21769..22182
                     /locus_tag="EHO50_RS37090"
     CDS             21769..22182
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676669.1"
                     /locus_tag="EHO50_RS37090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PaaI family thioesterase"
                     /protein_id="WP_128435699.1"
                     /transl_table=11
                     /translation="MTMTNAEADKILSANFAPWVLQLGLTVEAVEERRAILRMPWSDGL
                     AREGGALSGQALMAAADTATVIAVSAARGAYGPMTTVQQSTSFQRAVLGSDVLIEAVVT
                     KLGRRMAFADITMTDEGSGEIAARASTVYALLG"
     misc_feature    complement(22411..22426)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            22658..22873
                     /locus_tag="EHO50_RS37095"
     CDS             22658..22873
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="EHO50_RS37095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030052098.1"
                     /sec_met_domain="strepbact (E-value: 1.1e-35, bitscore:
                     115.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVATVEISDAELDNVSGGLQVNAVNGALDAVNGIAPVSGL
                     VDTVVGTVEGVTGLNTAPVSGLVAGL"
     gene            23105..23911
                     /locus_tag="EHO50_RS37100"
     CDS             23105..23911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="EHO50_RS37100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_128435702.1"
                     /transl_table=11
                     /translation="MQFRQQALAKLQSPEELDLPVRFARPQGWLVLSVTVVVMAAASVW
                     AVTGSVASTVGAPAILTHGQGSYILQSPVAGQVTAVLAEQGQRLPANSPMLKVRTAKGD
                     TVVRSVAAGRVTALAATIGQIISTGANVAAVEKVAHTKDALYATVYVPAENAASIPDKA
                     AVDLTVSSVPTQEYGVLRGHVKSVDRSAQSAQQIAAFLGDNQLGEQFTKDGRPVAVLVE
                     LDKESSTKSGYKWSSADGPPFSLTSMTMADASIRLADQRPVDWLLP"
     gene            23908..26133
                     /locus_tag="EHO50_RS37105"
     CDS             23908..26133
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978106.1"
                     /locus_tag="EHO50_RS37105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_128435704.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.4e-40, bitscore:
                     129.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAQETRSSRRRAAPPKRPVPKGRSKTVRTPTVLQMEAVECGAA
                     SLAMVLGHYGRHVPLEELRIACGVSRDGSRASNLLKAARSYGLTAKGMQMDTAALAEVK
                     TPAVLFWEFNHYVVYDGMGRRFGRRGVYINDPAKGRRFVPMEDFDGSFTGVVLVMEPGE
                     GFSKGGRKPGVLGAMPARLRGTAGTMPAAVLASLLLVVVGAAVPALSRTYIDMFLIGGQ
                     TSLLGVLFASMGTCVALTLMLTWLQQANLLRGRIISSTLSSARFLRHLLRLPVTFFSQR
                     SPADLVQRLQSNDAVAETLARDLAAAGVDAVVVVLYALLLYTYDPQLTFVGIGVALLNV
                     VAMRVVIRLRATRTAKLRADNARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTL
                     EEQQRLGVPSAWLGVVAPTLATLNSALILWIGGMRAVEGGISVGLLVAFQALVTRFTAP
                     ITRLNGVAGRIQDFAADVARLKDVENFEADPLYGRPGTGESTRRLNGHVELQNITFGYS
                     PLDKPLLTGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYAPWEGVIRIDDQRIEDIP
                     RGALASSVSFVDQEVFLFEGTVRDNVALWDPSIPDDAVVDALRDAALYDVVMRRPGGIH
                     SKVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETEQVVMDNLRKRGCAC
                     VVIAHRLSTVRDSDEIVVLQHGTIVERGRHEELVARGGAYATLVKER"
ORIGIN
        1 ccgcgcctga tcccggcgtc gcacctgatc ccggcgtccc gagaggcccg gagtgactcg
       61 attccggggg tgtaaggcgg gcgagaaggg gtacggggct ccacaaggag gcattcgtgc
      121 ccccgaacaa cgcctctgag cgggaaggag gtccatgaca gcgcattgca gtgtccgggc
      181 cgtttccctt tgcgtggggc ggcccggatc ttgttgaggc ccacgcgccg ttgacgccgg
      241 ctgtcagcgc ggaggcaacc ggtgcagttc cacgtccgtg aggcgaccct cggtcacggt
      301 ggcggtcatg taggtgcagt ggggctggcg acggcggtcg gtcggcgagc cggggttgag
      361 caggcgcagg ccggtcgggg cggtggtgtc ccaggggatg tggctgtggc cgaagaccag
      421 cacgtcgagg tcggggaaac ggctggcgca gcgcgtctcg cggccctggg cgggcccggt
      481 ttcgtggacc atgccgaagc gcagaccgcc gagttcgacg tacgccacct ccggtagccg
      541 ggcgcgcagg tccggtccgt cattgttgcc gtagaccccg acgagccggg cgcagcggct
      601 ctccagcagg tcgagcgtgg ccgcgtcgac ccagtccccg gcgtggaaca cgacgtcggc
      661 gcccgggagt tcggcgagca gcggatcagg cagtgccttg gcgcgcttgg gcaggtgggt
      721 atcggacatc agcagcagac gcacgccgtc aggctaccgg cgtggacgat cttccggccg
      781 gttctccacc agggcacacc gggcatcgac acacgggcag acctggcatc catgcgcacg
      841 gcatcgatcg ttgagcggtg gacaaaaggc gtgacagggc taggatttgg ccacggatgc
      901 cgtaatccga cgcaaacgcc cagcgacccc cagggggttc gaagaccgat gccggtcaag
      961 gtcagcgtgg tcgtccccgt gtacaacccc ggggtctatg tcgaggactg catcgcgtcg
     1021 ctgctcaggc agtcgctgcc gccggacgct tacgaagtga tcttcgtcga cgacggttcc
     1081 accgacgaca cacccgcccg gctcgacgcg ctcgccgcca ccgatccccg ggtgagggtc
     1141 gttcaccagg cgaactccgg ctggtcgggc aagccccgca acgtcgggat cgccgccgct
     1201 cgcggcgagt acgtgatgtt cgtggaccac gacgaccacc tcggcgacga ggccctggag
     1261 cggatgtacg actacggcgt ggccaacggc gccgatgtcg tggtcggcaa gatggccggc
     1321 aagggccgcg cggtgccggt ggagctgttc cgccgcaacc acccgcgtgc caccgtcgcc
     1381 aacgcgccac tgatcgacag cctcaccccg cacaagatgt tccgccgcgc cttcctcgac
     1441 gacatcggcc tgcgctaccc cgagggcagg cgacgcctcg aggaccacgt cttcgtcacg
     1501 gaggcgtacc tgcgcgcgag caatgtctcg gtgctcagcg actacgtctg ctactaccac
     1561 gtccgccgcg acgacgcctc gaacgccgga ttccagcgct tcgaccccgg cggctacttc
     1621 aagaacctcc gggaggccct ggacgtcgtc gagcggtaca ccgagccggg gccactgcgc
     1681 gaccggctgc tgcgccgctg gctgcgtgtg gagatggtcg agcggctgcg cgggcggcgt
     1741 ttcctcgcca tgccggggga ctatcgccgg gagctgttcg aggagatcca ccaggtcgtc
     1801 gtggagcgtt tcgggcccgg tgtcgcggcc gggctgcagc cgacgcagca ggtcgtcgcc
     1861 gcgctgatcg tggcggatcg gtacgacgac gtggaggcct tcgccgagtg ggaggccggc
     1921 atcgccctca cggccgcccc cgagcacgtg gtgtgggagg acggcacgct acgggtcggt
     1981 ttctcggccg agtacacggc cgccggtgag ccgatgacct tcgtcggcgg taagccgatg
     2041 gccgtcgccg acggtgagcc gacggccgtc gccgccgact cggcccgtac gccactcgac
     2101 ggcccgcccg gggatctggc cgcggcgatc gcccgggtgg gcgtcgacac cgtcgcccgg
     2161 ttcggcaagg ccaccgctga cctgctgctg cgcgagcgct ccagcgccgc ccagtacttc
     2221 cagccgctgg agttcacccg gcaggaggtg ccggcgggcg acgacggccg ggtccggctg
     2281 gtgctgcgtg cgaccgccgc cgtcgacccc gccaccctca cactgggcgg cgtgtgggac
     2341 gccttcgtcc gcgtcaagct gggcggctgg accaaggagt gccgcctcgg ccccgccccg
     2401 cgcgagggcc gccccgcccc gcacgccggt gtcgtcggcg gccacgtggt cctgccgtac
     2461 tggaccgcac cgcacaccaa cctcgccctg gacgtggacc gcgcgaccca ccgcgtcggt
     2521 ctcggcgccg tcaccccgga cgacgtcacg gcctcgggcg cccgactgcg cgcgctgctc
     2581 cccctgcacg ccccccacca cggcacggac gtctcgctcc gactcacctc gtccggcacc
     2641 acccatgacg tgcccgcaac cctgtccccg caagggtccg gagcccttct acaagccctg
     2701 ctgccgctgg cagacctgcg gggcacgacc tggcgcacgg cgctcggcac acctggcccg
     2761 cgctttctca cgctgccgtt cgccctgcgt gccggggtcg gcggagtgca agtggtgcag
     2821 acgtctcgcc ccgatccact gcgccgactt ctgcgcaggg cacggcgaag gctcggtaca
     2881 gccctggggc ggacggcggc ccggctgcgg gcccgggccc gcagggggtg acggcatgcg
     2941 atcgctcggc atcgaaggcg cgtgggcgct ggagcccaag gtcttccctg acgaccgggg
     3001 cagtttccat gagtggtacc ggggtgcgga gttccgcgag gccaccggct acgacctgtc
     3061 cctggcgcag gcgaactgct cggtctcccg ctggggcgta ctgcgcggcg tgcacttctc
     3121 ggacgtgccg cccggccagg ccaagtacgt gacgtgtctg cgcggcgccg tcctcgacgt
     3181 ggtggtcgac ctccgcgtcg gctcccccac cttcgcccgc tgggaggccc tgcgcctcga
     3241 cgacgacagc caccacgccg tgttcctcgc ggagggcctc ggccacgcct tcatggccct
     3301 caccgacgaa gccaccgtgg tctacctgtg ctcgacgggt tacgccccgg agcgcgaaca
     3361 cggggtacat ccgctcgacc ccgacctggg catcgcctgg cccgaacaca tcccgccggt
     3421 tctctccccc aaggacgcgc aggcgccgtc actggccgag gccgaacggg cgggcctact
     3481 cccgtcgtac gagacgtgca gggcctacta cgaccagctg cgcgcccctt aggggcgcta
     3541 cccggtgaac cgttcaaccg ccgtacgcaa cgcctcccac ccccgcgacc gtccgacacc
     3601 cagcctgcga gcccgcgtca acggccgcca aaagcccgcc ccgagcagcg cctcgggcgc
     3661 caccgcaccg gcccggtcca ggatcgtctc ggggaccttc tgcggatcgg gaacctcgta
     3721 ctcggccacg atctcgtcgt accgatcccg caacaccgtg ctgcgaggat cggcaccgaa
     3781 caccacgagt tgcccggtgg gctccgtatc gacgagcacg gtcaccagat caggacgata
     3841 ccggccgaga atctcggcga tcttgtacac gtcaccggtc cacgcaccgg tgtgccggtc
     3901 gcgagccgcc tcgtcgacgt tgcgcggcag catgtcgtcg aagacgatca cgctggccca
     3961 gtcggagtgc cgctcgatgt tgatgaagtc ccgcagcgcg tactcgaaca ggtgcatgcc
     4021 gtcgatgaac gacaggtcga ggacggtacg ccgccagtac ccgaacggac tgcgcccgcg
     4081 gcgcaggttg cgcaagggat gacgaccgcc cttgaggtgg atgagcgggt tgtcgcgggc
     4141 gaagaagtcg tcgctggtgg ccttgaccag gtggacgtcg cagcggatct ccgtgacgac
     4201 cttgaaggcg gggtcgacgg cgacggtggg gacgcgggag agtctgaggc tgcggccgtc
     4261 gttgacgccg atctccaggt agttgcggtt gccgctgacc ttgtgcagtt ccctcaggaa
     4321 ctcatggcgt ttcacgaagg gtctccttgc ggatccgggg cagtgcctcg tgcagagcgg
     4381 tgcgccagtc gcgcgctcgc gcgaggccga gccgctgccg acggccctgt gcgaggacgc
     4441 tgtacgcggg gcggggcgcg ggccggggga aggcctcgct ggtgacgggg cgcacccggt
     4501 cggggtcggc gcctagcagc tggaacacct cgcgggccag gtcgtaccag gtggcttcgc
     4561 cggagttggt ggcgtggagg atgccggtcg cgtcgacgcc gacgcgcggg ccgaggtcgg
     4621 cgatcgtcgc ggcgacgtcg gcggtccagg tgggctggcc gcgctggtcg tcgacgacgt
     4681 cgacggtgtc gcggctcgcc tcgagctcga tcatcgtgcg gacgaaactg cggccgtgga
     4741 cgccgtacag ccaggcggtg cgcacgatgg cgctggacgc cggcagttcg tccagtacgg
     4801 cccgctcgcc ggcgagtttg gtgcggccgt aggcggtgcg tggggcggtg ggatggttct
     4861 ccgcgtaggg ggttcgggcg tcgccggcga agacgtagtc ggtggagagg tggatcaggc
     4921 gggcctcgta cgcggtgcag gtgtgggcca ggaggcccgg tccgtcgccg ttgatgcgca
     4981 gggcgcgctc ctcgtcctgc tccgcgtcgt cgacggccgt gtatgcggcg cagttgacga
     5041 ccaggtcggg gcggtacgcg gcgagggcgc ggtcgacggc gtcggcgccg gtgatgtcga
     5101 gggcggcgtg gccgaggccg gccacctgct cgccgcgggc gaggagttcc tcgaccaggt
     5161 cgcggccgag catgccgccc gcgccggtga ccagccacct catccgtgct cctcaccgac
     5221 gcgtcgcttg aggggttccc accaggcgcg gtggtcgcgg taccaggcga cggtggcggc
     5281 gaggcccgcg gcgaagtcgt ggcggggccg gtagccgagt tcggtgcggg ccttggtcca
     5341 gtcgacggag tagcgcaggt cgtggccctt gcggtcctcg acgtgctcca cccggtccca
     5401 gtcggcgccg catgcctcca gcagcagggc ggtgaggtcc ttgttgctca actcggtgcc
     5461 gccgccgatg ttgtagatct cgccggggcg gcccttggtg cggacgagct cgacggcgtg
     5521 gcagtggtcg tcgacgtgca gccagtcgcg gacgttgagg ccctcgccgt agagggggac
     5581 ctgctcgccg tcgaggaggt tggtgatgaa gagcgggacg accttctcgg ggaactgatg
     5641 cgggccgtag ttgttggagc agcgggtgac gcggacgtcc aggccgtgag tgcggtggta
     5701 ggcgagggcg agcagatcgg aggaggcctt ggaggcggag tagggcgagc tgggccgcag
     5761 ggggtcctcc tcggtggccg aacccgtctc gacggagccg tagacctcgt ccgtcgatat
     5821 gtgcacgaag ggtgcgacgc cgtagcgcag ggccgcgtcc agcagggtgt gggtgccgac
     5881 gacgttggtg aggacgaagt cgtcggcgcc ggcgatcgag cggtccacgt gggactcggc
     5941 ggcgaagtgc accacctggt cggcctcggc catcagcttg tcgaccagct cggcgtcccg
     6001 gatgtctccg cgcacgaact tcagccgggg gtggccgagt tcgagattgt ccagggtgcc
     6061 tgcgtaggtc agcttgtcca gcaccgtgat ccgtggtgtt tcgggcgcgc cgggtgcgtt
     6121 cggtgcgtcg cgggcgagca gcgtgcggac gtacgtcgag cctatgaagc cggcggcgcc
     6181 ggtgacgagg aggttcatgt gtggatctgc accttgctgt ggtctccgag gacgaggcgg
     6241 tgggcgctgg gaacgctggg cgcgggggtg acctcgacgt gccggccgat gagcgaggac
     6301 tcgatccgac ccaccccgtc gatccaggag tcccgcagca cgatggagaa ctccaactcg
     6361 ctgtccgtga tacggcagtt ctccgcgatg gaggtgaagg gaccgacgta ggagtcctcg
     6421 acgacggtgc cggtgccgac gacggcgggg ccgacgatgc gcgagttgac gatgcgcgcc
     6481 ccctcctcga cgaccacccg tccgacggtc tccgacgcgt cgtcgacgtc gccgtcgata
     6541 cggcgcgcga ggccctccag gacggtgcgg ttcacctcca gcatgtcggc gacgttcccg
     6601 gtgtccttcc agtagccctt gatgaccgtg cagcgcacgt cggcgcgggc gtcgatcagg
     6661 tgctggatgg cgtgggtgat ctccaactcg ccacgccagg acggtgtgat ggcgcggacc
     6721 gcgtcgtgaa tggccggcgt gaacagatac acgccgacca gggcgaggtc gctcttgggg
     6781 tgctccggtt tctcctccag gccgatgacc cgtcccgcgt cgtcgagttc ggcgacgccg
     6841 aaggagcgcg ggtcctggac gcgggtcagc aggatctggg cgtcggggcg gttgccgcgg
     6901 aactcctcga cgaggtcggt gattccgccg acgacgaagt tgtcgcccag gtacatcacg
     6961 aagtcgtcgt cggcgaggta gtcgcgggcg atgaggacgg cgtgggccag tcccagcggg
     7021 cgttcctgag ggatgtaggt gatctccaga ccgaacttgg aaccgtcgcc gacggcgtcc
     7081 tggatctccg cggcggtgtc accgacgatc acaccgacgt cggtgatacc ggccgcggcg
     7141 atggattcca gcccgtagaa gagcacggcc ttgttggcca caggcacgag ctgtttggcc
     7201 gaagtgtgcg tgatcggcct caagcgcgta ccggcgccac cggacagcac gagagccttc
     7261 atctgcttca ccttagcccc gattacgccg atttgacggc gccgggtttg gcttgttcgt
     7321 cactgccggg ccgcaggccg ttcaccggga tcggcctcac ccgcccagtg cgacctcgct
     7381 ccacacctgt tttccgccac tgaccggcac cgtcccccac gccgccgaca tggcctcgac
     7441 caggaggatg ccgcggccgc cggtggcctc ccagctgatg ccggccggtt tgaccggtgt
     7501 gcggggtgag gcgtcggcga ccgccacgcg cagccgctgg ttgacgaggg tgaggtcgag
     7561 gcggacccgg ccgtcggtgt gcacgagggc gttggtgacg agttccgaga cgacgagcag
     7621 gacggcgtcc atgtcctgcg ccggcaggcc ccatgagcgc agggtgcgcc gggtgaagcg
     7681 gcgggcgtgg ccgacggcct ccgggacgcg ccagaccgtc cagctctcgc gcagtgggcg
     7741 cacggccatg ccctcgtagc gcaggaggag cagggcgacg tcgtcgctgc ggcgtgcgcc
     7801 cacgagcagg gcgtcggcga cgaggccgag gtgggcgggg tcggagcggg cgagtgcgtg
     7861 ggcgagccgg tcgattccgg tgtcgatgtc ggcgtcggcg gactcgacga ggccgtcggt
     7921 ggtgagggcg atcacggtgc cgggctgcag ccgcagcggg ctcatcggga agtcggcctc
     7981 ccgcatcacg ccgagcggcg gaccgccctc cgcctcggcg atctccgtgc tgccgtcggg
     8041 gtggcgcagc accggcggga ggtggcctgc gcgcacgcac caggcggtgc cctcctccag
     8101 gtcgacgtcg acgtaggcgc aggtggcgaa gaggtcggtc tccatgtcga tgaggagccg
     8161 gttggcgtgg tggaccacca cgtccggcgg gtgcccctcg gcggcgtagg cacgcagtgc
     8221 ggtgcgcatc tggcccatga gggtggcggc ggccgcgctg tggccctgga cgtcgccgat
     8281 gacgagggcg acgtggttgt cgggcagcgg gatcacgtcg taccagtcgc cgccgacctc
     8341 cagtcctgcc gtggtgggca gatagcgggc gacggccttc gcgccgggca gccggggcag
     8401 tcggcggggc agcagctggc gctggagcat gccgacgagt tcgtgttcgg cgtcgacggc
     8461 gtgggcgcgc aggagggcct ggccggcgag gccggcggag gcggtgagca gggcgcgctc
     8521 gtcggggccg aagtcgtgcg gggcgtccca gccgatcagg caggcgccgg ccatccggcc
     8581 cccggcgggc aggggcagga cggcgaggcc gccggggccg acgtcggcga gggcgggctc
     8641 caggggggtg ccggcgggcc agatctgggg gcggccctcg cgcagggcgg cggcgagggt
     8701 cggcatggcc cggaccggcg cgtccggcca ttcggtacgc cattccgtgc gccacagctg
     8761 cggccaggac tcgggttggg gcgggtcgag gacggtgacg acgaggcggt cgttctccag
     8821 ctcggcgagc gcgatgcggt cggcgtgcag cggcttgcgc agggcggtga cgacggcgtg
     8881 gctgacgtcg cggacggtgc cggcggtggc gagggcggcg gccagacgct ggacgcgggc
     8941 cacgtcggtg acctcggcgc gcagggtgga ggtgtcggcg acggtgccga cgaggcgggc
     9001 cgggtggccc tcgccgccgg gcaggaggcg gccgcgcagc ctgagccact tgggcggtcc
     9061 gctgggctgc aggacccgga actccagctc gcggtcgccg atggacatgt ggccggcctc
     9121 gacgacggac atcagcgacg gcaggtcctc cgggacggtc aggcccagca gggtctcgac
     9181 cttgccgtcg aagtggtccg ggcggaggcc gaacagctcc aggatgtcgt cgccgacctc
     9241 gacgcggccg gtgtccatgg cgaggctgaa cgcgcccgcc ggcagctcgc cgccctcggc
     9301 ggccgcgggc agggcgggaa aggcgacggc ctcggcgatc agctgcaggc aggcgcggtc
     9361 ctcggcgtcg aagccgcccg gactctcgct cacggccgcc agacagccgc cgccgtcgtc
     9421 gccgtggagg ggcaggacgg ccaggtggaa gtcccgcgac ggcacgcgcc gtgcctccgc
     9481 gcagtcggcg agctccgccg ggcccagcca cagaggtaag ccggtgcggt gggcgtcggc
     9541 gaccggggac ggtccggcca gggcgtagcc gtcgcgcagt ccgtacaggg tccggggcac
     9601 gccggcggac tcgaccaggc acagcagctc gccgtcctca ctcggcgtgt acacggcggc
     9661 gaaggaggct ccgccgaaga cgagcgcctg ctccaggacc cggcgcagcc gctcgggcga
     9721 gtccggttcg acggcaagcg ccttcagggc gtcttcggcg cgcagactcc tcgtcctgcg
     9781 tcccgcggca ccctcattga ccacgttcgc cattacagcg cttatgagac acctgcgcag
     9841 cccctgtgac cgttcgatgg agggtcgacg agggtcgcgc tcgaaaacct ccgaacactt
     9901 cttgacgtat gcgttccgca cgtcgatctc gtgacaggca tgactgtccg cgcccgccgg
     9961 cccgctggaa gtgtcgacgt cgggccacgg agggggacgc atggacaagc ggtacgaggt
    10021 gtacgcgctc gccgaccggc acttctacga gacgcctgaa cgtatgtcgg cagggacgcc
    10081 gggcaccggg ctcggctacg agacggcacg gcgcgaggtg ccggagggct gggacgcggc
    10141 gcggatcggc gactggctga cgctcacgcc gctcggcgcg gacggggccc cggtgcccgg
    10201 tccggcccag ggctggaaga tccacgcctc ggccacccgg ggcaacgcgg agcgggtggc
    10261 cgcgatcgtg tgggactact gcgtgccccg gcgcatctcg ttcaagttcg tgcccagccc
    10321 gcatctgctg catctgcgca acaccaagta cgcggcccgc gacaccagcg gcaagttcgt
    10381 cacgatctac ccggccgacg aggagcagct gcacgtcgtg ctgcgcgagc tcggcaagct
    10441 cctggagggc ttcgaggggc cgtacatcct caccgatctg cggtggtacg acggcccgct
    10501 ctacgtccgc tacggcgctt tcgcgcggac cttcgtcgtc gacgagcgcg gctcgctcgt
    10561 gccggcggtg gtggacggcg agggcaagcg ggtgccggac cggcgggcgc cgtccttcca
    10621 ggtgcccgag tgggtgacgc tgccggcctt cctggagccg catctggccg cacgcaacac
    10681 cacgacggtg ggcgaactgc cctaccgcat cgagaaggcg ctgcacttct ccaacggcgg
    10741 cggggtgtac tcgggcaccg acacccggga cgggcgcaag gtcgtgctga aggaggggcg
    10801 gccgcacgcg gggctggccg ccgacggggc ggacgcgatc agccgcctgg agcgggagaa
    10861 gtccgccctg gagcaggtgg cggggacggg cgtggtgccg gaggtgcggg actggttcac
    10921 gctcggcgac caccggttcc tggtcatgga tttccttcag gggcgcccgc tgaactcgtt
    10981 cttcgcggag cggcatccgc tgctcacccc ggatcccgat ccgaaggcgg tggccgagta
    11041 cacggcgtgg gcggtacgca tccacggggc ggtgcagcgg gcggtggagg cggtgcacgc
    11101 gcgcgggatc gtcttcaacg acctgcacgt cttcaacatc atggtcggcc ccgacgagga
    11161 gtcggtgtcc ctgctcgact tcgaggcggc ggcgccggtc gaggagaacg gccgccaggt
    11221 ggtcgcccat cccggcttct tcgccccacc ggaccgcacg ggcgccgacg tcgaccgcta
    11281 tgcgctggcc tgtctgcggc tcgccctgtt cctgccggtc accacgctgt tcgtggtcga
    11341 ccgggggaag gcggcccatc tggcggaggt gatcatccgt cagttcccgg acgtgccaag
    11401 ggagttcctg gacgaggcgg tcgcggagat cacgcggggc accacagcgc ccgcaccgtc
    11461 cttcgtcgag ccgggcgagt ggccgttcag ccgcgactcg atggtcaagg cgctgctcgc
    11521 ctcggcgacg ccggagcgcg atgaccggct cttccccggc gacatcacac agttcaacga
    11581 cggcggcggc ctcgggctgg cgcacggtgc ggccggagtg ctgtacgcgc tggacgcggt
    11641 cggcgccgag cggtacgagg agggcgagcg ctggctcctg gcccgcaccg cgccgccgcc
    11701 gacgggcaca ccgctggggc tgtacgacgg tctcgcgggc gtggcccacg tcctggaccg
    11761 gctcggccac cggcagcgcg ccctcgacct ggtcgagagg atcctcgcgg aacggtggca
    11821 gaacctcgcc tccgacctgc acggcggact ggccggactc gggctggtgc tcggcgaact
    11881 ggcccgtacc acaggcgagt cggagctgct ggaccgtgcc gccgaagccg ccgacattct
    11941 cgtacgacga ctcgcgcagc cccttgcgga cagcccgaag cgacgtcggg ccgggctgct
    12001 gcgaggggcg agcgggcccg cgctcttcct gctgcgacag cacgaacgga ccggagagcc
    12061 actgctgttg aaggctgccg aggtggcgct gcgccgggac ctggactgct gtatgacgca
    12121 cccgaccggc tcgctggagg tcgacgaggg ctggcggacg ctgccgtacc tcggtgacgg
    12181 gagcgcgggc atcgggatgg tcctggacga ctacctcgcc cacggcgccg actccgaggg
    12241 tgagttcgag cgtgcgcgcg ccggcatcct gaccgccgcc accagccgct tctacgtaca
    12301 gcccggtctg ttccagggcc gcgccgggat gatcctgcac ctcgcgcgca cggacacgcc
    12361 cggcgcgacc cgggagcggc tcgccgaaca gatcgaggga ctcggctggt tcgcgatgga
    12421 ctaccaaggc caactggcct tccccggcca ccagatgatg cggctgtcga tggacctgag
    12481 caccggaacg gcagggtgcc tgctcgcgct cggcgcggcc ctcgacaccc cggccaccgc
    12541 tcacctgccg ttcctgccgc cgctcgggcg gccccacata cgcggttccg cgacttgacg
    12601 gagccgtgac ccaaccccgt ccccacgggt ggacgacacc gaaggaagga aaacgagatg
    12661 gcacttctcg acctgcagac gatggagtcc gacgagctca ccggcggcgg cggcgccagc
    12721 acgctcagcc tgctgtcctg tgtcagcgcg gcgagcctga cgctctgtct ctgacgagca
    12781 ccgtgcgccc atgattccgg gcggtccact cccgcgaggg aggggccgcc cggggtcctg
    12841 cgcacaccaa ggggtgaacc gaggggtgag ggccagagcc gtatgacaca agccatcagg
    12901 acgctccccg ggccgctcgg cccggccccc gcccgctgtg tggtcctgtg cctggtgagc
    12961 acggcctcca ccggcgtcgg tctgctgctg cccgccgcgc tggggcacac cctggacctg
    13021 ctgctgtccc agtccccagc cacccgctgg gtgctgtact gcaccgcgat cgtcgtgctg
    13081 ctcgccctgc tcgacgcctg cgagaccgtg ctgggcggca cggtggacgc ccgcaccacg
    13141 gcttggctgc gccgccgtct gaccgggcat gtcctgaccg tcggcccccg cgccgccgcc
    13201 cgcttcggac ccggcgacct cgtcgcgcgt ctcgtcggca acgccgccca ggccggcacg
    13261 gcaccgaccg cccgggccgc tctgctcgcc gcgctcgccg gaccggtcgg cggcgtggtg
    13321 gcgctcgctc tcatcgaccc gtggctcgcg gccgtactgc tggccggggc accggtgctg
    13381 gcgctgctgc tgcgcgcctt cgcccgcgac accagggact gcgtgacgcg ctaccagcag
    13441 gcgcaggggc ggatcgcgca ggcactctcg gaagccgtgg gcggccaccg caccatcgag
    13501 gcggcgggta cggccgaccg ggagacggca cggatcctgc ggccgttgcc cgaactgtcc
    13561 gacgccgggc accgcatgtg gcgggtccag gggcgggccg cgggccggtc cgtcgcggtg
    13621 gccccgctgc tccaactcgg cgtggtcgca gttgccgggg tgctgctcgc ccggcaccgg
    13681 ctgacggtgg gcgaggtgct cgcggcctcc cggtacgcgg tcctcgccac cggcgtcggc
    13741 gtcctggtcg gtcatctcgc gggcctggcc cgggcccggg cggcgaccgc ccggctcgac
    13801 gaggtcctcg ccgagcccgc tcccggatac ggcgagcgct cgctcccgcc cggcccgggc
    13861 cggctggaac tgcgcggggt gaccgccctg cgcggtgggc gtcgcgtgct cgacggagtc
    13921 gacctcgtgg tgcccggcgg gacgacgctc gccgtcgtgg gccggtcggg cgcgggcaag
    13981 tcactgctcg ccgcgatcgc cggacggctg gccgaaccgg acgcgggaga ggtgctgctc
    14041 gacggcgtgc cgttgcgtga actcacccac gacacactgc gccgggccgt cggccacgcc
    14101 ttcgagcgcc ccgccctgct gggcggcacg gtggaggagg agatcggcct cgccctctcc
    14161 tcccccgccc ccgaccgcgt ccgggaggcg gcccgtacgg cccacgcgga cgacttcgta
    14221 cgccgcctgc cccgcggtta cgccaccgcc gtcgccgacg ccccgcgctc cggcggggag
    14281 tcccaacgcc tcggcctcgc ccgggccttc gcccacggcg gccgtctgct gatcctcgac
    14341 gacgccctct ccagcctcga cacggtgacc gaggcccgca tcaccgcggc cctcgtgagc
    14401 agcggcccgc acaccggcac ccgcctcctg atcgcccacc gcgccgccac ggccgcccgc
    14461 gcggacgcgg tggcctggct ggacgggggc cgggtgcggg cggtggggcg gcacgaggaa
    14521 ctgtggcaga tccgtgacta ccgggcggtg ttcgcggacg gggagcagcc atgaccgagc
    14581 acgtccaccg gcgcggcctg cgcttcctgt gggaccggtg gcgggtcgtg gcacgcctgg
    14641 ccggctggtc cgttctggag accggccaga ccttcctcac cgggttcgcc ctcgcccgcg
    14701 ccctggacga ggggtttctg gccggacggc ccggaatcgg actcgcctgg ctcggggtgg
    14761 ccgggctcgg cgtgctcgtc ggggcgtacg gcacggtacg ggtgtacggc gcggtcgccg
    14821 cgctggtcga accgctccgg gaccggctgg tcgcgcgggt cgtcgcgcgc ggggtacggg
    14881 aagcggacgc cggggccctg tccgggctga cccagcaggt cgagatcgca cgggacacct
    14941 tcgccgggct ggtgatggtg tcgcgttcgt tcgtgttcac ctcggtcggc gccgtcgccg
    15001 gactggtgtc gctcgacccg ctgctcctgc tggtcgtcgg acctccgctc gccgcgggtc
    15061 tcggcctgtt cgcggcgaca ctgcgaccgc tggcccgccg ccaggaggcg ttcctcgtcg
    15121 ccgacgaggc gctggccgac cggctcggca ccgtctgccc ggggctgcgg gacatcacgg
    15181 cggccggtgc ggaggaacgg gtcgccgcca ccacggggat ctgtgtcgac accgagctgc
    15241 gggccgcctc ctccctcgcc cgctggggcg tcctgcgcgt ggtttcactc gccctcggcg
    15301 gccaactccc gatcgtcctg ctcctcgcct gcgccccctg gctcctccag cacggcgtca
    15361 ccgccggcgc actggtgggc gccctcgcct acgtcaccca gtccctgctc cccgccctgc
    15421 gcaacctggt ccacggcctg ggcacgagtg gctcacggct ggcggtcgta ttgcgacgcc
    15481 tgactcggga aacgtcctcc ctggccgggg ctgcgactgg agctgggatc ggggccgggt
    15541 ctggggctgg gtctggggct ggggctgggg ctggggctga gaccggagct gaggccggga
    15601 ccggagctgg agctgggcct gagaccggag ccgggcctgg ggcagccccg cccgtcctct
    15661 ccctcacctc cgtcaccttc gcctacggcc ccgacgcgac ccccgtcatc gacgacctgg
    15721 acctgaccct cgcgcccggt gcccatctgg ctgtcgtggg gccgagcggg atcgggaagt
    15781 ccacgcttgc cgcgctggtc gccgggctgc tggaaccggg gcgcggcacc gtccggctgt
    15841 gcgggcaccc ggtgcccggg gccgaggccg ccgcgctcag ggtgctcatc ccgcaggagg
    15901 cgtacgtgtt caccggcacg ctcgccgaga acctcggcca tctgcggccg gaccccgtgc
    15961 ccgaggcaga gctgctcgcc gcggccaagg cggtggggct cctgccgttg ttggaggcgc
    16021 tcggcgggcc caccgcgacg gtggatccgg cggcgctctc cgcgggtgaa cgccagctcg
    16081 tcgccctgac ccgggcctat ctcgcgcgcg ccccgctcgc cctgctcgac gaggcgacct
    16141 gccacctcga cccgcgggcc gaggagcggg cggagcgggc cttcgcccag cggccgggcg
    16201 gcaccctggt ggtcgtcgcg caccgcatca gctcggcccg ccgcgccgac cgggtactcg
    16261 tcatggacgg ccgccacact gcgtacggca cacacgacga actcgtacgc cgctcggcgt
    16321 cgtaccgcgc tctcgtcggc agctggacgc ccgagccgtc agagccagcc ctcgccctgc
    16381 gagatccgga tcgcgtcgat gcgattgcgg gcaccggtct tacgggtgat ggcggccatg
    16441 tagttgcgca cggtcccgtg cgacagatgc aggctccccg cgatctccgc caccgaggct
    16501 ccctcggcgg cgagggataa cacgctcagc tcccgccggg tcagcggcat ctcggcggcc
    16561 ttgaggaagc cgaagcccag cgagtcgtcg acgaaacgtt ccccctcggc gaccttccgg
    16621 atcccctgca caagctgctc gggcgagccc tccttgtcga cgtagccgag cgccccggcc
    16681 tcggcggccc gtttcagcag gcccggtctg tgcgcgctgg ccagcacgag gagcctgggc
    16741 ggtgtccggc cggcctcccg tccgcagagg tcgcccagcg gtgggatgcc gtagctgtcc
    16801 gagcagtcga ggtcggccgc gcaaacatcc ggacgcacgg atcgcagacg gcggggcgcg
    16861 ctctgccacg aggcgtcgaa cacccccagg tccggttccc ggcgcagcca ctccgcaagg
    16921 accgatctga ccagacacgc gtcgtgcacc agaagcaccc ggatcactgc ccgtcccttc
    16981 gactcgccct gcaccggttc cttggtgaaa tgcgcgtgcc ccattgttcg tgttcggcac
    17041 caccaccggg cgcgaagaac cggccatcag ggtgcgcggg ggcgcacgcg cggcgcccgt
    17101 acgctggcct gcgcttcgac tgcgggggca tgacccgggg ccgagggggt acgtggcgga
    17161 ctcgccggga gggtgcacac gcgtgcccgg acacggccct gcgccggtgc cgacgggcgc
    17221 tcgccgggcg ctcgccgtgc gcgaagggcc gcgagggagg agatttgagc cctggggccc
    17281 gacgcgcgtg agcggctcgg gtcgcctccg ggacgcgccc gtgcgaggag gtggtcggcg
    17341 tgtccgacgg gcagacgtcc gcccaggcac cggcggccgc gaggacgcgg gtcggccggc
    17401 cactgctgtc gctggcgctg gcgtcgatga tggacgaggt gcacgcgcac tccggtgccg
    17461 tgtacctgct ggcggcggac gagcccgtac tggagatggc ggtgatggcg gggctgcccc
    17521 gggcgttcgc ggcgccgtgg gaacgggtcg ggctgagtgc gccgatcccg gtcgcggagg
    17581 cggtgcgtga gcggcgcctg gtgtgggtcg ggggcgagga ggacatggcg gcccggtatc
    17641 cgcgtatcgc cgtcgtcctg ccgtatccgt tcgcactggc cgcgctgccc gtggccaccg
    17701 gcaccaccgt ctacggcgcg atcttcgtga cctggcccgg ttcgcattcc ccggagctgt
    17761 cggagcggga gcaggaacat ctgaacgcgg cctgccgccg gctcgcggtg cggctggagc
    17821 gcgccatgga ggacagccgc ccgccgctgc ccgagcccga tctgctcgcc gggccggcgt
    17881 tcagcggcgc ggccggcacg ctcggcacgg tggaggcggc ccggatggtg tcgcggctgc
    17941 cgtacgggct gtgctcgctc gatctgcacg gccggatcag cttcgccaac ccggcggcgg
    18001 ccgagctgat cggcgtcccg gccaaccgac tgctcggcaa ccagctgtgg gcgtcggtgc
    18061 cctggctcaa cgaccccgtc tacgaggacc gctaccgggc cgcgctgatg agccagcaga
    18121 ccacgtcgtt cgtcgcgctg cgcccgcccg gggactggct gtcgttccgg atgtatccga
    18181 gcacgaccgg tctgagcgtg cggatcagca gggcccgcgc ggtggccgag atgggccgca
    18241 gcggacccca gcccggcgat gcgccggctc ggctggtgac catctcccag gtgctgagcc
    18301 tggccggtgc gctcaccgag gcggcgggtg tgcaggacgt ggtgcagctg gtcgcggacg
    18361 agatcgtgcc ggccgtcggc agccaggccc tggtcgtcct gggctcgcgc gcgggccggc
    18421 tgcatgtgct cggccaccgc ggctatccgg atccgcagat cgtggagcgg ttcgacggaa
    18481 tgccgctgac caagcagact ccgggcacgc atgccctgag caccggggtg cccgcgttct
    18541 tcgagtccca ggagcagctg gagcgcctgt atccggtgcg gctcgcgact ccggacggct
    18601 tcgcggcctg ggcgtatctg ccgttgatcg cttccggccg gccggtcggc acgtgcgtgc
    18661 tcgcctacgc cgagccgcat gcgttcccgg cggacgaacg ggccgtcctg accagtctgg
    18721 gcgggctgat cgcgcaggcc ctggagcgag cccagctcta tgacgccaag aaccagttgg
    18781 cgcacggcct gcaggccgcc ctgctccccc actcgctgcc gacgctgccc ggcgtcgaag
    18841 cggccgcgcg ctatctgccc gccatgcagg gcatggagat cggcggcgac ttctacgacc
    18901 tggtgccgac ggaggagggc ctggcggcgg cggtgatcgg ggacgtgcag ggccacaacg
    18961 tcacggcggc gggcctgatg ggccagatcc gcaccgccgt acgcgcgtac acgaccgtcg
    19021 gtcaggcgcc ggaggaggtc atgcgcagca ccaaccggct gctgctcgac ctcggttccg
    19081 acctgttcgc cagctgcctg tacctgcggc tcgacccgga acacgggcgg gcggtgatgg
    19141 cccgcgccgg gcatccgccg ccgctgctga gacggccgga cggacgggta cgggtgctgg
    19201 acctcgccgg tggcccgctg ctgggcatcg acggctcgcc cacctatccg acgacggagg
    19261 tcgaactcac gcccggctgc gtactcgtcc tctacaccga cgggctgatc gaatcccccg
    19321 gcgtcgacat cgaagacgcg ctcgccgacc tcggccaggt actcaccgag gccggggaac
    19381 gccccctgga cgagctggcc gacctgctgg tccagcacgc cgcgtcggta cgggaacggg
    19441 tcgacgacgt ggcactgctg ctgttgcggg cacggggctg agggcagggg tgggcgcggg
    19501 gacggatgta gctggggact gaccgcacgg ctgcgggtgc ggtaggggtt gggggctgac
    19561 cgcacggctg ccggtgcggg tagaggctgg ggactgaccg cacggctgcg agtgcgggtg
    19621 cggggtgggg gcctgacacg gggctcggct gacggcaggg tgcgggcttg ggccgatgcc
    19681 ccggccgggg cggagggctg acagcacggc cgtagacctg gggccgacaa cacggctgcg
    19741 gagacggggc ggagccaacg gcacggcagc gggcccgggc caataacccg gccaggagcg
    19801 gtgggtcgac gacaccgccg cagacccgac gccgacaaca cagccgcggc cccagggcaa
    19861 aaccaacggc acggcaacgg gccccggcca ataacccggc caggagcggt cggccgacaa
    19921 cacccccgca gacccgacac cgacaacaca gccgcggccc cagggcaaaa ccaacggcac
    19981 ggcaacgggc cccggccaat aacccggcca ggagcggtcg gccgacaaca cccccgcaga
    20041 cccgacaccg acaacacagc cgcgcggcgg gctggcgacc cggccgttgc cggcgcgctg
    20101 actacccgac cttccacccg acctttgcgg gcgcgaggtc cgcggccccc gacgcggagc
    20161 ggtccgaccc tcccgccgga gggtcggacc acgtttcgtg cggatcggct cggatccgtg
    20221 cgccggtgtc ggtgtgtcag ttcacgccga cgccgttgcc gacgatctcg ccgaggccgt
    20281 tgccagtgcc gtcggcgttg ccgttgccga cctcttcacc ggccccggct tcctcaccgc
    20341 cgacctcttc accggccccg gcctcctcac cggctccggc ctcctcaccg gcgcccgctt
    20401 cctcgcccgc gcccgcttcg tcgccggcac cggcctcctc gcccgcgccc gcgccgcccg
    20461 cggcgtcgcc gccgagggtc gcgccgaccg cctccagggc ggtggtcacc ggctggaaga
    20521 acgtctcgcc gccgacggtg cagtcaccgc tgccgccgga ggtgaggccg atcgccaggc
    20581 cgtcctgggt gaacagggag ccgccgctgt cgccgggctc ggcacagacg ttggtctgga
    20641 tgagcccggt gaccgtgccc tccgggtagt tcacggtggc gtcgagtccc gtgacctggc
    20701 cgtcgttcag cccggtggtg ctgcccatcc ggaggacctg gagacctacc tcggcgtcag
    20761 cggcctggct gatcgcgagg gtctggtcgc cgaggttgac ctcgctgggt gcctcggtgg
    20821 ccgggtcgtc gtacttgacc agggcgaagt cgcctgcgcc ggggaaggtg gcctggtcga
    20881 cggtggcgat cggctgaccg ccctcggcgt ccgaccactg ctcggccgcg accccgcagt
    20941 gcccggccgt caggaaggcc ggggtgccgt cgcccgcggt gacgttgaag cccgcggagc
    21001 agcgtgagcc gccggcgaag atggcgtcgc caccggagag gaaggtcttg aaggttccgg
    21061 ccgacttctt gatggtcgcc atgccggagc cgaggctctg gacggtcgac tccagctggt
    21121 cccagttgtc gccggtgacg gtggagtcgg cggtgacgag gatcttgttc gttctggggt
    21181 cgaccgccca ggccgtgccc gggatggtcg cctcggactt cagggtctgc gcgccggacg
    21241 cgagctccgt caggctgttc tcgacctcgc ggaccttcgc gcccgccttc ttcgcctgaa
    21301 cgatcacgtt gttgttgtcg ccggggacga cattgacgac gagctgctgg ctctcggcgt
    21361 cgtagtacga accggcgaag gcgtcgccga gcaggcccga gagctgcgag gcgagatccg
    21421 acgcgtccgc cgccttcagg gtcttggggg cggcggcgtc gtttgacgcg ccgtcctggg
    21481 acgcgttggc gttcggcaac aggatcgcgg ccgctccgag cgccaccacg ctgcccgcgg
    21541 ctatcgcggc cttgcgcttc ggaattcgct tgtgactcaa acttctcgac ctcctggggg
    21601 acggggtctg tgccgccgtt cgtccggcag cttttcgggg cgcctggttg gcagttggta
    21661 cgcacgcttc gagtggagcg ttcaactccg ttcgcaccca ccccgttcga aacaccgaat
    21721 cggccaagga ccgcgcccac aggtccggcg gcgggaacaa tcccccatat gacgatgacc
    21781 aacgccgaag ccgacaagat cctctccgcc aacttcgccc cctgggtcct gcaactgggc
    21841 ctgacggtgg aggcggtgga ggagcgccgc gcgatcctgc gaatgccctg gtcggacggg
    21901 ctcgcccggg agggcggcgc gctgtcgggg caggcgctga tggccgccgc cgacaccgcc
    21961 accgtgatcg ccgtgtcggc ggcgcgcggg gcctacgggc cgatgacgac ggtgcagcag
    22021 tcgacgtcgt tccagcgcgc ggtgctcggt tcggatgtcc tgatcgaagc ggtcgtcacc
    22081 aagctgggcc gccgtatggc gttcgccgac atcacgatga ccgacgaggg gtcgggagaa
    22141 atcgcggccc gggcgagcac ggtgtacgca ctactgggct gacacgatct gctaccgatc
    22201 agtagcggtc ggtcgtgaac accgaccgga accctgactt cagggaatct gcacattcaa
    22261 tactcaacga agtcaccgtg gaccggggtt ctccacaggg cgctacccac ggtcaccccc
    22321 ttggggcggg agtgtcggat tcgacaccgc acgggtcggg tcttcgccgg gcggacgcaa
    22381 cagctcgcca gagccgatgc tgtgacgcat gtgaagaagt cgccgacaag acgtgcccgc
    22441 gtctgcacgg atcgatgccg ccgagatcaa agtgccctgg tgaggccgga gtttgattgg
    22501 aagcccgtag ccgcagcgtg ctttgatcca tcgcaccgca ggggccgcga acggcttccg
    22561 gaaacgggcg tcgggcgcct gcggtcgcgg ccgtcatctg tccccagagg gggccgctcc
    22621 cccttgtgaa atacccatta ggaagggaag ttccatcatg aactccaccc cccaggttgc
    22681 gaccgtcgag atctccgacg ccgagctcga caacgtctcc ggcggcctgc aggtcaacgc
    22741 tgtgaacggc gccctcgacg ctgtcaacgg cattgccccg gtttccggcc tggtcgacac
    22801 ggtcgtcggc accgtggagg gtgtcaccgg cctgaacacc gccccggtct cgggtctggt
    22861 cgccggtctc tgatcgcgcc tttgtaccgc tgagtcccgg agcccttccc ggctccggga
    22921 ctctcgggtg ccatgctgca tttcccccgg agacaacccc cagccccccg gcagaaaagc
    22981 aggtcggccg gatgaccggc atggacatca cggggcaaac cggagcaaca caaggcgcca
    23041 tccgcagaac gaccggcccg ctcgagcgcc ggtctcacgt catcctcagg tgagggaaag
    23101 ttccgtgcag ttccgccaac aggccctcgc caagctccag tcaccggagg agctcgacct
    23161 tccggtgcgc ttcgcccgcc cccagggctg gctggtgctc tccgtcacgg tggtcgtcat
    23221 ggccgccgca tccgtgtggg cggtgaccgg ttcggtcgcc tccacggtcg gcgcgcccgc
    23281 catcctcacc cacgggcagg gcagctacat cctgcagagc ccggtcgccg gccaggtcac
    23341 cgcggtcctc gccgagcagg gccagcggct cccggcgaac tcccccatgc tgaaggtccg
    23401 taccgccaag ggcgacacgg tcgtccgttc ggtcgccgcg ggccgggtca ccgcgctcgc
    23461 cgccaccatc gggcagatca tctcgaccgg cgcgaacgtc gccgccgtgg agaaggtcgc
    23521 ccacaccaag gacgcgctgt acgccacggt gtacgtgccc gccgagaacg cggcctccat
    23581 ccccgacaag gccgccgtgg acctcaccgt ctcctccgtg cccacccagg aatacggcgt
    23641 cctgcgcggc catgtgaagt cggtggaccg ctccgcgcag tcggcgcagc agatcgccgc
    23701 gttcctcggg gacaaccaac tgggcgagca gttcaccaaa gacggcaggc cggtcgccgt
    23761 actggtcgag ctggacaagg agtcgagcac caagagcggt tacaagtggt cgtccgcgga
    23821 cgggccgccg ttctccctca cctccatgac catggccgac gcctcgatcc ggctggccga
    23881 ccagcgtccc gtcgattggc tgctgccgtg agcgccgccc aggagacccg cagcagcagg
    23941 cgccgcgccg ccccgccgaa gcgccccgtg cccaagggca ggtcgaagac cgtccgcacg
    24001 ccgaccgtgc tccagatgga ggcggtggag tgcggtgccg cctccctcgc gatggtgctg
    24061 ggccactacg gccgccatgt cccgctggag gagctgcgca tagcgtgcgg tgtctcccgt
    24121 gacggctcac gcgccagcaa tctgctgaag gcggcccgca gctacgggct gacggccaag
    24181 ggcatgcaga tggacacggc cgcgctcgcc gaggtgaaga cgccggccgt cctgttctgg
    24241 gagttcaacc actacgtcgt ctacgacggc atgggccgcc gcttcggccg ccgcggcgtg
    24301 tacatcaacg accccgccaa gggccgccgt ttcgtgccca tggaggactt cgacggcagc
    24361 ttcaccggcg tcgtgctggt gatggagccc ggcgagggct tcagcaaggg cggacgcaag
    24421 ccgggcgtcc tcggcgcgat gccggcccgg ctgcgcggta ccgcgggcac gatgcccgcc
    24481 gccgtcctgg cgagcctgct cctggtggtg gtcggcgcgg cggtgcccgc gctgagccgc
    24541 acctacatcg acatgttcct catcggcggc cagacctccc tgctgggcgt gctgttcgcg
    24601 tccatgggga cctgcgtcgc gctcaccctc atgctgacct ggctgcaaca ggcgaacctg
    24661 ctgcgcggcc gcatcatctc ctccaccctg tccagcgccc gcttcctgcg gcatctgctg
    24721 cggctgccgg tgacgttctt ctcccagcgc agcccggccg acctggtgca gcgcctgcag
    24781 tcgaacgacg cggtggccga gaccctggcc cgcgacctcg cggcggcggg cgtggacgcg
    24841 gtggtcgtcg tcctctacgc gctcctcctc tatacgtacg accctcagct caccttcgtc
    24901 ggtatcggcg tcgccctgct gaacgtcgtc gccatgcggg tcgtcatccg tctgcgcgcc
    24961 acccgtaccg cgaagctgcg cgcggacaac gcccggctca ccaataccgc ctacaccggc
    25021 cttcagctga tcgagacgat gaaggcgacc ggcggcgagg acggctactt ccgcaagtgg
    25081 gccggacagc acgccaccac gctggaggaa cagcagcgcc tcggcgtgcc gagcgcctgg
    25141 ctgggcgtgg tcgcccccac gctcgcgacc ctcaacagcg cgctcatcct ctggatcggc
    25201 ggcatgcggg cggtcgaagg gggcatatcc gtcggtctgc tggtcgcctt ccaggccctg
    25261 gtcacccgct tcaccgcccc gatcacccgc ctcaacggcg tcgcgggccg catccaggac
    25321 ttcgccgccg acgtggcccg tctgaaggac gtggagaact tcgaggcgga cccgctctac
    25381 ggccgccccg gcaccggcga gtcgacgcgc cggctcaacg gccatgtgga gctgcagaac
    25441 atcaccttcg gctacagccc gctcgacaag cccctgctga cgggtttcga cctgacggtg
    25501 ggacccggcc agcaggtggc cctcgtcggc ggctccggca gcggcaagtc gacggtttcc
    25561 cggctgatct cgggcctgta cgccccctgg gagggcgtca tccgcatcga cgaccagcgc
    25621 atcgaggaca tcccgcgcgg cgccctcgcc tcctccgtct ccttcgtcga ccaggaggtg
    25681 ttcctcttcg agggcacggt ccgcgacaac gtggccctgt gggacccgtc gatcccggac
    25741 gacgcggtgg tggacgccct gcgcgacgcc gcgctgtacg acgtggtcat gcgccgcccc
    25801 ggcggcatcc acagcaaggt agagcaggac ggccgcaact tctccggcgg gcagcgccag
    25861 cgactggaga tcgcacgggc gctggtacgt cgccccagca tcctggtgct ggacgaggtg
    25921 acgagcgcgc tggacgccga gaccgagcag gtcgtgatgg acaacctgcg caagcgcggc
    25981 tgcgcctgtg tggtgatcgc acaccggctc agcaccgtgc gcgacagcga cgagatcgtc
    26041 gtactccagc acggcacgat cgtcgaacgc gggcggcacg aggagctggt ggcgcgcggt
    26101 ggcgcgtacg cgacgctggt caaggagcgg tgagatgacc tccgtccacg agggtgacct
    26161 cgtcctcaac gcgctcgggc agatgggcac gcgcatcgac tgcgccggat tcaaccgcct
    26221 cgacctcgaa ggcccgcagg tgctgtggct ggtcgcgtcc ggcgcggtgg acctgttcgc
    26281 ggtcgacgcc ggacagcagg gccactggca ccacctcggc cgtctggagg caggctcgct
    26341 gctcctcggc cctgtcccgg gaccgcacca cacgctggtg gcacgcccgc tgagggactg
    26401 cgtcgtgcac cgcatcggcc tgcgcgagtt gtaccagccg gcgaacaccc agacctggtc
    26461 gtacgacgag tacggcaacc cgcagtacgt cccaccgacg acgagcccgc tggagtacgc
    26521 cctcgcgctc ggcgtcggcc gtagcctctc catcctcttc caggcgccga tggccaccga
    26581 gcgggccgcc gagatgaccg acgacgacgt cttctggatg caggtaccgc cgggcagtgt
    26641 gcagtacggc tcgctgtacg gcgcggaagc cgccgccgac ctgctgatgg acccggcggt
    26701 ctggcagtcc atggtcgacc agcagtaccg cctgctgacc acgctggacc gctggatcga
    26761 gcagctggag cgcactcacg agacgcgcac cgcggcgggc atcaaggccg gcgaggcggt
    26821 gcgcgcccag gccgaccgca cgctgctggc gtccatcggc aagcgcagcg acaagcgcac
    26881 gacggccgcc gacgcggacg ccagttacgc ggcctgcaag ctggtcgctg aagcagccgg
    26941 gatcacgctg gccgagcccg cgcagagcgg caccgagagc gaccggctcg acccggtgga
    27001 gcgcgtggcc atcgcctccc gcgtccgtac cagggcagta cgcctggacg ggcggtggtg
    27061 gcgggacaac gtcggcccgc tcgtcggtca ccgggcgctg tccggtgcgc cggtggcgct
    27121 gctgtggcgg cgcggtggct atgtcgccgt ccatccggcg accggccggg agacgccggt
    27181 cgagaaggcg aacgcggagg agttcgagcc gcgtgccgtg atgttctacc gtccgctgcc
    27241 cgaccgtgcg ttgagcccgc tgaggctgct gcggttcagc atgcggggca cgggcgggga
    27301 tctgacgcac ctcctgatca gcggcctggt gacggtggcg atcggtgcgc tggtgccgat
    27361 cgcgacgggc aaggtgctcg gcgagttcgt gccgaaggca cagaccgggc tgatcgtgca
    27421 gttctgtctg gccgtgatga tcagcggtgt cgtggccgcg gcgttcatgc tgctgcagaa
    27481 cctgacgatc ctgcgcctgg agggtcgtat cgaggcgacg ctccaacctg ccctgtggga
    27541 ccggctgctg cggctgccca cgaagttctt caccgagcgc tcgaccggcg agctggccag
    27601 ccaggccatg ggcatcagcg cgatccgccg gctgatggcc ggagtcggcc ccgtcgtcgc
    27661 gtcgtcggtg acggtgggcg cgatgaacct ggcgctgctg ttctggtaca gcgtgcccat
    27721 ggcgatggcg gcgatcggca tgctcgtcgt cattgcggcc gtgttcctgg ggctcgggct
    27781 gtggcaggtg cgctggcagc ggcggctggt ggtgctgagc aacaagctga acaaccaggc
    27841 gttccagacg ctgcgcgggc tgccgaagct gcg
//
