LOCUS       NZ_RQJW01000009        21146 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces cyaneus strain CGMCC 4.1671 Scaffold8_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RQJW01000009
VERSION     NZ_RQJW01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces cyaneus
  ORGANISM  Streptomyces cyaneus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 416179)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Streptomyces sp. nov., a novel actinobacterium isolated from a karst
            cave sample
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 416179)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-NOV-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135 Xingang West Road, Guangzhou, Guangdong 510275,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-OCT-2018
            Assembly Method                   :: SPAdes v. 3.6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004028635.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 03:28:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,717
            CDSs (total)                      :: 8,635
            Genes (coding)                    :: 8,413
            CDSs (with protein)               :: 8,413
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 222
            CDSs (without protein)            :: 222
            Pseudo Genes (ambiguous residues) :: 0 of 222
            Pseudo Genes (frameshifted)       :: 77 of 222
            Pseudo Genes (incomplete)         :: 187 of 222
            Pseudo Genes (internal stop)      :: 12 of 222
            Pseudo Genes (multiple problems)  :: 50 of 222
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:58:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 174725
            Orig. end                         :: 195871
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RQJW01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21146
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11146](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(780..1193)
                     /locus_tag="EHO50_RS31175"
     CDS             complement(780..1193)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="EHO50_RS31175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_004925829.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVSISLYKQRGAGPGPA"
     misc_feature    1322..1335
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            complement(1443..1703)
                     /locus_tag="EHO50_RS31180"
     CDS             complement(1443..1703)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="EHO50_RS31180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_078916258.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPVALNETCPECLAEGMHPVQLRLCLSCGHVG
                     CCDSSPGRHATEHHKESGHPVMRTFEPGEEWRWCFVDHVLV"
     gene            1951..3546
                     /locus_tag="EHO50_RS31185"
     CDS             1951..3546
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="EHO50_RS31185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_128434574.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAVAAGARRSPVPAPLLLVAAGLAVSYVPGVP
                     EYTLDPHIVLPLVLPPLLHTAATDSSYLDLRAQMRPVMLLSVGYVLFATFTVGWAAYLV
                     VPDLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLVNDATAITAYRVA
                     LAAAVGEGATWAGGIGEFLLAALGGIGMGLVLMVPIHWLRTHLKEALLQNTLSLLIPFV
                     AYAAAEQVHASGVLAVVVVALFLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGEYEGGRAAWYAVAVFVVVVVSRFVWVYPATFLPRMLSARIREREDNPTW
                     KGPFIISWAGMRGVVSLAIAFSIPLTVHGGEDFPERNLILFLTFTTVIGTLVVQGVTLP
                     PLIRLLKLPGRDAQAETLAEANAQAQASRAAEQRLEELLSDERNALPDPLADRLRAVLE
                     RRRNSVWERLGQANPVTGESVDDTYRRLSREVIGIERTVFVKLRDGRYIDDEMLRTLLR
                     RLDLEEAAAYREAG"
     gene            3651..6551
                     /gene="fxsT"
                     /locus_tag="EHO50_RS31190"
     CDS             3651..6551
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047688.1"
                     /locus_tag="EHO50_RS31190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_128434575.1"
                     /transl_table=11
                     /translation="MAGTSQRFFISYAGADRLWAEWVGWHLERDGHLVELDVWDWRTGD
                     DFVQRMDDGLEKADAVVALFSKSYFEDGRWTQEERSAVVARRDRVLPLAVEPLSNHEVD
                     PMFAAKVRMNLHGLDEAAAIEALRAAVSGAGRPTERPAFPGSPAEAPDGSAGPAVPEGP
                     RPALPGDTGEPEVWNVRRRNRDFSGREAQMVQLRDGLLSGRQSVVYALHGMGGIGKTQI
                     AVEYAHRFASQYDLVWWIDAEQSDQIPIHYTELADRIGVALAEAGAEHNARMLLQHLRT
                     RPRWLIILDNAEDPDQIEPWLPEGPGHVLITSRNPNWRRLAHPTALDVFSRADSLAYLR
                     TRIPGIPEAQADTLAQDLGDLPLALAQAAGMIETGTPVDHYRRLLNDSTSRILREGDVP
                     DYPVPLAAAVGIAVEGLDARHPDATALLRIAAFLGPEPIPTEWLVNARPRLSTIPGDPH
                     DPLWTRAALEPLRRYGLARIDGEALQLHRLTQAVLRDQVDPAQAEAIHDDAAAVLAAVE
                     PGDPEPPANWPIWANLTSHLWSQHLDVTRRPELRPVLRNAVNFLIRSAQPRTAAELAAT
                     LREAWTAESGPDHPDVLTCTQYLGHATSDLGDIRAARPIIEDAFVRRRRMLGDDDPDTL
                     QSANDFAAILSALGEFQEALRIDEDTLTRRRRVLGEEHPKTLQSAGNLGAALTALGEYV
                     AARGTHEGTLARRRRVLGDGHPDTLRSTLGLAESLRLLGDVTEARRLQEETQARCRSTL
                     GDDHPLTLNAVQGLAATLNDMGEYGKVRSMLEDVIARRRRVSGADHPQAVKAAYGLAHA
                     LNALCEHEEARRLLADVLAWERRVLGPDHPDTLKSAHALSAALDGLGDHAESRRLLEDT
                     IARRRRVLGEDHQETLISTHNLGVTMCNLRSLAAGAKLLEDVRARQRRTLGDGHEDTQA
                     TTRSLAAAYRQMGLHRKAQKLTPKKSTKRGFGRKSR"
     gene            complement(6552..7454)
                     /locus_tag="EHO50_RS31195"
     CDS             complement(6552..7454)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998014.1"
                     /locus_tag="EHO50_RS31195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_128434576.1"
                     /sec_met_domain="PALP (E-value: 1.6e-20, bitscore: 68.2,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPDPTALHPRLPSPLQEAADERFTRRGIRLLLKRDDLIHPELI
                     GNKWRKLAPNLTAAAGRPIVTFGGAYSNHLRATAAAGRLLGLPTVGVVRGQELAERPLN
                     PSLARCVADGMRLHFVDRSTYRRKTDPETQAAILRAAGAEEAYVVPEGGSNALAVRGCR
                     ALGEELRGQADVVAIACGTGGTLAGLAAGLDPGQQALGIPVLKGAFLADDVRGLQTEAF
                     GGPRGDWRLDERFHFGGYARTTPALDAFAEDFEERHGVPVERLYVAKLLYGLVTLAEEG
                     AFGAGAVVVAVVTGAPFGG"
     gene            complement(7561..8151)
                     /locus_tag="EHO50_RS31200"
     CDS             complement(7561..8151)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491240.1"
                     /locus_tag="EHO50_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_128434577.1"
                     /transl_table=11
                     /translation="MASPMSASRFLERLRAEGATVVEVGDWEHHNRNHVGPWGPVHGVM
                     IHHTVTEGSAHTVELCRNGYEGLPGPLCHGVITKDGRVHLVGYGRANHAGLGDDDVLRA
                     VIAEKALPPDNEANTDGNRHFYGFECENLGDGQDPWPEPQLDAIERVSAAICRHHGWTE
                     RSVIGHLEWQPGKVDPRGFTMAWMRERIRERLK"
     misc_feature    8258..8272
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.12"
                     /tool="antismash"
     gene            8468..9874
                     /locus_tag="EHO50_RS31205"
     CDS             8468..9874
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="EHO50_RS31205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_128434578.1"
                     /transl_table=11
                     /translation="MSVGEEVRTEQDKPQQSLGTAAARNLATTTKSAPQMQEISSRWLL
                     RTLPWVNVQGGTYRVNRRLTYAVGDGRITFVKTGDRVEVIPAELRELPALRSYEDEDVL
                     SELAQRCQQREFAAGNLITSFGSRTDEVYLLAHGRVEKLGSGPYGEDESLGVLADGAYL
                     GEQALIDPDTIWEYTVRAVTACTVLALRRQDFEQVAERSDSLREHLEQLRAAPEQRTNK
                     YGEKEIDLAAGHSGEPDIPHTFVDYEARPREYELSVAQTVLRIHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLNNCEYDQRLQPHDGVPSPDDMDELLCRRRGTK
                     LFLAHPRAISAFGRELNKRGLVPETIEIAGNRIPTWRGVPIYPCNKIPVTEARTTSIIA
                     MRTGEAEQGVIGLQQAGIPDEIEPSLSCRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            10001..11146
                     /locus_tag="EHO50_RS31210"
     CDS             10001..11146
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674923.1"
                     /locus_tag="EHO50_RS31210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_128434579.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.4e-60, bitscore:
                     197.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFMTETEQRPAGARPSTETLERRRPIAIDMDGGSGASPPDGPE
                     AALILERVRASVDPELRAAVESLPPSMRRIARYHFGWEHPDGTPAAGNAGKAIRPALVL
                     TAAAALGGPAARAAAVQAAVAVELVHNFTLLHDDVMDRDTTRRHRPTVWAVFGDADAIL
                     AGDALQALALRLLAEDPHPASAPAAARLAACVVELCAGQHADTSMEKRGPGDVGLDEVL
                     GMAEAKTGALLGCACALGALYAGAADEHVAALDAFGRESGLAFQLIDDVIGIWGDPSRT
                     GKPAGADLAARKKSLPVVAALTSGGPAAAELAALYEMPYDKEDLQATALAVERAGGRDW
                     AQAQAADRMARAMQELARAVPDPEQAGGLLALAEYVTRRSN"
     misc_feature    complement(11163..11177)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            11418..12011
                     /locus_tag="EHO50_RS31215"
     CDS             11418..12011
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998010.1"
                     /locus_tag="EHO50_RS31215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_128434580.1"
                     /transl_table=11
                     /translation="MGVRIRTAGEGDRELVVRLLDAAFQDDPVSGWVFPGEEHRRTTHP
                     KLMAAFTDIVSAVGRIDVTEDGTACALWISVPAVEQDLDDEGPARLRAQVDPENERVEL
                     IGRLTAGIHPSGRAHEYLWMIAAAPGHQGEGLGTALMNSVLDRCDRDGLPAYLEASSDR
                     SRKLYERLGFELQGRPLDLPDGPRMWPMWREPRG"
     gene            complement(12125..12715)
                     /locus_tag="EHO50_RS31220"
     CDS             complement(12125..12715)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998009.1"
                     /locus_tag="EHO50_RS31220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_128434581.1"
                     /transl_table=11
                     /translation="MAGNPERRAALVDAGVEVLAREGARGLTFRAVDAEAGVPVGTASN
                     YFTGRDDLLRQIDARLHLRLAPDPEVIAGLLTRPKDRSLVTAFMHDLMARATRDRTGYL
                     ALLEMRLEAGRRPELRSSFTKSVRGDLEEGMEFHRNAGLPGGDEVVTVLYLAMLGLLLE
                     HLTLPDVLEGTLPGVSVPDGLVERIVETVVPEG"
     gene            12838..13422
                     /locus_tag="EHO50_RS31225"
     CDS             12838..13422
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="EHO50_RS31225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_128434582.1"
                     /transl_table=11
                     /translation="MRKLTYFIACSLDGFIGDPSGDASAMLAFVDEEYLAFLKSEYPET
                     LPTHGRRALGLDGLENKRFDTIIQGRGSYDLALKEGVTSPYAHLREYVASRTLTESPDP
                     NVEIIGGDLVAKVRELKAEDGEFGIYLCGGSQIAGELLDEVDELVIKSYPIVYGAGMPM
                     FGSDLAVTEFTLDAVRSFGNGAVVRTYSRKR"
     gene            13449..13694
                     /locus_tag="EHO50_RS31230"
     CDS             13449..13694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657883.1"
                     /locus_tag="EHO50_RS31230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128434583.1"
                     /transl_table=11
                     /translation="MGSEEHVCPDCGQPVDTVVRRHKTLGAWVPTWVAGPCRNPECSAY
                     SEGDAEHEERHARERKPEPESERKPEQPEAPTAKNP"
     gene            13790..14203
                     /locus_tag="EHO50_RS31235"
     CDS             13790..14203
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005315313.1"
                     /locus_tag="EHO50_RS31235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YciI family protein"
                     /protein_id="WP_128434584.1"
                     /transl_table=11
                     /translation="MKYLVMVQGTQADYEAMQGKASEHSVAWSQEEIQAMYAYMQAIND
                     DLAETGEMIDGQGLAEPAKVRHVTLGDDGKAVITDGPYSETKELLAGYWVLDCASLERV
                     TEIAERVARCPQPAGAPVYPVVIRPILDGAGDC"
     gene            14211..15437
                     /locus_tag="EHO50_RS31240"
     CDS             14211..15437
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998006.1"
                     /locus_tag="EHO50_RS31240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_128434585.1"
                     /transl_table=11
                     /translation="MAGPTETEDLLRRHAPQVLGALVRRYGHFDTAEEAVQEALLAAAE
                     QWPRDGAPDNPRGWLIKVAARRLTDALRAEESRRAREEKVAALTPRDAFTAPAPGADRA
                     PREDDTLTLLFLCCHPDLPPPAQIALTLRAVGGLTTAEIARAYLVPEATMAQRISRAKQ
                     KVRGVRFGRPDNWEDRLPAVLQTLYLIFNEGYTATSGASLTRRELAGEAIRLTREVHRL
                     LPEHGEAAGLLALMLLTDARRDARTGPHGELVPLDEQDRDRWDKAAIEEGVALVTRALS
                     QGRAGPYQLRAAIAAVHDEAPSAEETDWREILGLYDVLVRLVPGPVERLNRAVAVAMVQ
                     GPRAGLAELDALEDELGAGHRLDAVRGHLLERAGAHDEARAAYEAAAAKTLSLPEQRYL
                     HARAARLRP"
     gene            15447..15779
                     /locus_tag="EHO50_RS31245"
     CDS             15447..15779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674925.1"
                     /locus_tag="EHO50_RS31245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_128434586.1"
                     /transl_table=11
                     /translation="MPEQTYILHITERSLWDAAREHGTYEISTRGRTLREEGFIHCSTR
                     AQLPSVAAFLYGSYDGPEELVVLVVDPARLGVPLKYEAPEPGGEEFPHVYGPIPVDAVV
                     DVEPWG"
     gene            complement(16002..16766)
                     /locus_tag="EHO50_RS31255"
     CDS             complement(16002..16766)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571365.1"
                     /locus_tag="EHO50_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_128434588.1"
                     /transl_table=11
                     /translation="MSIRWTYAFVDRPAESFARAHAFWAAVTDTRLSEFRGEQGEFVTL
                     LPGGEADACVKVQGVGSGAGGAHLDFAVDDVPEFVKSALQRGAGLAAEHDGWAVLRSPA
                     GQLFCAVPWQGESVRPPVVRGSRLDQVCLDVPPSLYDTEVAFWSDLLAGWASAPGSRPE
                     FHVLRPPAGLPVRILLQRLGEERPGEGRSGSAHLDLACADIAAARARHEELGAAFVAQG
                     AHWTVMRDPAGGVYCLTARDPETGGLTGASAS"
     gene            16946..18103
                     /locus_tag="EHO50_RS31260"
     CDS             16946..18103
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058926.1"
                     /locus_tag="EHO50_RS31260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_128434589.1"
                     /transl_table=11
                     /translation="MDHITFLVAVVIVTALAFDFTNGFHDTANAMATSIATGALKPKTA
                     VLISGVLNVVGAFLSTEVAKTISGGIVDDTLVTPGMIFAGLVGAILWNLLTWLVGLPSS
                     SSHALFGGLIGAVWVGAGSHGVHFDKVVEKVLIPAVASPLVAGVAALLATYLAYKLTSR
                     ARKQSVTKGFRLGQIASASLVSLAHGTNDAQKTMGVITLTLISAGALGHDAGPPVWVIA
                     SAGLAIGLGTYLGGWRIIRTMGKGLTEIQSPQGFAAETASTTVILTSAHLGFALSTTQV
                     ASGSILGAGLGRRLAEVRWGVAGRMVVAWLVTLPAAALVGGVSAGVVKHGGNLGTAVVA
                     LVGAAVAAGIVLVSRRNPVSAHNVNDAHEVTIRSTEEPTTVGTAA"
     gene            18152..18385
                     /locus_tag="EHO50_RS31265"
     CDS             18152..18385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123531.1"
                     /locus_tag="EHO50_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128434590.1"
                     /transl_table=11
                     /translation="MNLDWTALGQVAAVSLAVTVAVVTVFALGVLGLARYERAREEGAG
                     TSTVGGAQAGLCFVACAAVVAYGIYLIVPQFH"
     gene            complement(18436..19902)
                     /locus_tag="EHO50_RS31270"
     CDS             complement(18436..19902)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356876.1"
                     /locus_tag="EHO50_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_128434591.1"
                     /transl_table=11
                     /translation="MPIPLEPPLRRRPPLWPIPLLWTLGLGLWGLSRQHSVWRDEAATW
                     QVARRSVGEIWHMLGQVDAVHGLYYLLMHALFECFGPGTTTLRLPSVLAMAVAAACVTV
                     IGGRLAGAWAGLAGGLAFGLLPAVQFYLQEGRPYALIAAGAGISTLLLVTVLDGRGRAV
                     HWAAYGGTVAVCGLLNWLSLLILPAHLATLLWTRARRGTWTRWAVAAVTAVVAVLPLIL
                     FSRRQSDQVSWIPPLTWHMLIGPAVLLAIGGLGALLDRPRAGRLSVAAVGLPLLAVPQL
                     GLVGLSLVRPLFLDRYVLFSMLGLALLIGTALGTAVRAVRPRFPRSSAWLVPVVVVVAV
                     VALLPQSMAKRSPASRVDDVMAVAADVRRLKQSGDAVVFIPAARRDTALVCPDDFAGLR
                     DIALAQSPVASGTLKGEEAAPARIRGAMLAQRRILLVTDVPAVARPVSAERDKMKTAVL
                     KEHFRVVADVQVRGRRVTAYERLGAADNSA"
     misc_feature    complement(20103..20118)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     misc_feature    20677..20693
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     misc_feature    complement(20777..20792)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.41"
                     /tool="antismash"
ORIGIN
        1 ggagcggccg tgctgctgcg agagctccgc ggtcgccgtg gtgagcgcga ggcgcagctc
       61 ctgcaggcgc cgaggcaccc gcaccgccca gcccttgtcg cggaagtgcc gcttgatctc
      121 gccgaccacc gtcggggtcg cgtaggtcga gaactcgacg ccgcgctccg ggtcgaagcg
      181 gtcgaccgac ttgatcaggc cgatggtggc gacctgggtg aggtcgtcca gcggctcgcc
      241 gcggttgcgg aagcggcgcg cgaggtgctc gaccagcggc aggtgcatac ggaccagcct
      301 gttgcgcagc tccgcgtact cggggctgcc gtccttcagc ttgcgcagct cgacgaacat
      361 ggcgcgcgcc ccgctgcggt cctgagggtc gtgctgggtg gcctgcgcag tgtgcgcgcc
      421 catcgccacg tcctcggcgt ttcgctcgtg ctcgctcatc gtcccgcccg ttgccctctc
      481 ccgaggcctc gcctccacac ggactgggga gaccccgatc cgtccgcccg gaggcgcgct
      541 ctgcacggca ccctcgtcat cccgtccgtc gtccagggag ccggcctcca cggagtcgtc
      601 ctccgggtgt ggccgggcct gctcggggat gccgtcgatg ccgcccacca cgcgtcggga
      661 accgctcgga ccgctcgggc ccacccccag gctctcggct ccgtccgagc aggggggagt
      721 gccgtccggc agctcccgtg tgccgcgctc ttcgtcccgc accggcccgt ccccgttcct
      781 cacgccggcc cgggtcccgc gccgcgctgt ttgtagaggc tgatcgaaac ggttttgtcc
      841 tcgtccacgg cggaggagac cttgcccgcg agggcggaca gcacggtcca ggcgaaggtg
      901 tccctggagg gggcgtggcc gtccgtggtc ggggccgaga cggtgacctc gagtgagtcg
      961 tcgacgagcc ggaacacgca gctgagcacc gagccgggca cggcctgctg gagcaggatc
     1021 gcgcacgcct cgtccaccgc gatgcggaga tcctcgatct cgtcgagggt gaagtccaaa
     1081 cgggccgcga ggccggcagt cgccgtacgc agcaccgaca ggtaggcacc cgcggccggc
     1141 agccggactt ccacgaagtc ctgggtcgcg ggctcgcctg cgatctggga caccctcacc
     1201 tccaaggtgg tacaagcttc tcggggccga gggttgcccc ccggggtaac gcgatgtgtg
     1261 gttcagcggt gacgctatcg cgctctgaac tttcctgtcc ccaggacccc aaccccttgc
     1321 cgtcactcac agtaaacctg tggatacgct ccgtgtctag gggtctgcgg ctccaattgg
     1381 gaagagcgcg cgccgggttg acgtacccag acgtcagacg gtcgaaccgt ccggatccag
     1441 ggtcacacga gtacgtggtc cacgaagcac caacgccatt cctcgcccgg ctcgaaggtc
     1501 cgcatcaccg ggtgaccgga ctccttgtgg tgttctgtcg catgcctccc cggcgaggaa
     1561 tcgcagcagc cgacatgccc gcagctgaga cagagccgca gttgtacggg gtgcatgcct
     1621 tccgccagac actccggaca cgtctcgttc agcgccacgg gttccgggtg cggcagcgcg
     1681 tcggcgtgcg tgcactgttt catgattgcc aggttacgac ggccgcgagg atggccgcgc
     1741 ggaaaaacga gggcgggcgt acggcgatga tcaagtgcgg tccacgacga gggatcgagg
     1801 gcgggcgcag accatgagcg agcgcgggcg aaggacgacg gcgcccgggt gcgggcggac
     1861 ggcgaggggc ctgggccacc gtggcacggt gcaccgtgcc atgctgcacg cgcgcgtggg
     1921 cgccgggacg gacgagggcg ggcgagacgc atggacgtga tgccgctgct gttgctggtg
     1981 gcgggcagtg ccgcggtggc cgcgggcgcc cggcggtccc ccgtgccggc gccgctgctg
     2041 ctcgtcgccg ccgggctcgc ggtgtcgtac gtgccgggcg tgcccgagta caccctcgac
     2101 ccgcacatcg tcctgccgct ggtgctgccc ccgctgctgc acaccgcggc gacggacagc
     2161 tcgtatctcg atctgcgggc gcagatgcgg cccgtgatgc tgctgtcggt gggatacgtg
     2221 ctcttcgcga ccttcacggt cggctgggcc gcgtatctcg tcgtgccgga cctgccgctg
     2281 accgcggcgc tggtgctggg cgcggtggtg gcgccgccgg acgcggtcgc ggcgacggcg
     2341 gtcgcgcgcc gggttgggct gccgtcccgg atcaccacga tcctgcaggg cgagtccctg
     2401 gtgaacgacg ccaccgcgat caccgcctac cgcgtcgcgc tcgcggccgc cgtcggagag
     2461 ggcgccacct gggccggcgg catcggcgag ttcctgctcg cggcgctcgg cggcatcggc
     2521 atggggctgg tgctgatggt gccgatccac tggctgcgca cgcacctgaa ggaagcgctg
     2581 ctgcagaaca cgctctcgct gctgatcccg ttcgtcgcgt acgcggccgc cgaacaggtg
     2641 cacgcctccg gggtgctggc ggtcgtggtg gtcgcgctct tcctggggca ccgcgcgtgg
     2701 gaggtcgact tcgccacccg gctccaggag gaggcggtgt ggaagatggt cgcgttcgtg
     2761 ctggagtcgg cggtgttcgc gctcatcgga ctgcagcttc cggtggtcct caagggcctc
     2821 ggggagtacg agggcggacg tgccgcctgg tacgcggtcg ccgtcttcgt cgtggtcgtc
     2881 gtctcgcggt tcgtgtgggt gtatccggcg accttcctgc cccgcatgct gtcggcgcgg
     2941 atccgggagc gtgaggacaa cccgacctgg aaggggccgt tcatcatctc gtgggccggg
     3001 atgcggggcg tggtctcgct ggccatcgcc ttctcgatcc cgctcacggt gcacggcggc
     3061 gaggacttcc ccgagcgcaa cctcatcctc ttcctgacct tcacgacggt catcggcacg
     3121 ctggtcgtcc agggcgtcac gctgccgcca ctgatccgcc tgctgaaact ccccggccgc
     3181 gacgcacagg ccgagaccct cgccgaggcg aacgcccagg cgcaggcctc ccgcgccgcc
     3241 gagcaacgcc tggaggaact cctctccgac gaacgcaacg ccctcccgga cccactggcc
     3301 gatcgcctgc gagccgtcct ggaacggcgc cgcaactccg tctgggaacg cctgggccag
     3361 gccaacccgg tcaccggcga gtccgtcgac gacacctacc gacgcctgtc ccgcgaggtg
     3421 atcggcatcg agcgcacggt gttcgtgaag ctgcgggacg gtcgctatat cgacgacgag
     3481 atgctgcgga cgctgctgcg cagactggac ctggaggagg cggcggccta ccgggaggcg
     3541 gggtgagcga ccgacccggg gtacgtcgtg cgcagttccc tacccgcgtg cgcctctgac
     3601 ggtggatcat agaagggacg cgatcggtac tgggtgactc ggggggctcg atggccggca
     3661 cctcacagcg gttcttcatc agttacgcgg gggccgaccg gctgtgggcc gagtgggtgg
     3721 ggtggcacct cgagcgggat ggtcaccttg tcgagctcga cgtgtgggac tggcggaccg
     3781 gggacgactt cgtccagcgg atggacgacg ggctggagaa ggcggatgcc gtcgtggctc
     3841 tgttctccaa gtcgtacttc gaggacgggc gttggaccca ggaggagcgg tccgcggtcg
     3901 tcgcccgccg ggaccgggtc cttccgctcg cggtggaacc cctgagcaac cacgaggtcg
     3961 atcccatgtt cgccgcgaag gtgcggatga acctgcacgg cctggacgag gccgcagcca
     4021 tcgaggcact gcgggccgcg gtgagcgggg ccgggcggcc gaccgagcgt ccggcatttc
     4081 cggggagccc tgccgaggcg ccggacggat ctgccgggcc cgcggtgccc gaggggccca
     4141 gaccggcgct gccgggcgat accggcgagc ccgaggtgtg gaacgtacgc cgccgcaacc
     4201 gcgacttctc cgggcgcgag gcccagatgg tccagctccg agacggtctg ctcagcgggc
     4261 ggcagtccgt cgtgtacgcg ctgcacggga tgggcgggat cggcaagacg cagatcgccg
     4321 tggagtacgc ccatcggttc gccagccagt acgacctggt gtggtggatc gacgcggagc
     4381 agagcgacca gatcccgatc cactacacgg agctggctga ccggatcggc gtggctctcg
     4441 ccgaagccgg tgccgaacac aatgcccgga tgctgctgca gcacctgcgc acccggcccc
     4501 ggtggctgat catcctcgac aacgcggagg accccgacca gatcgagccg tggctgcccg
     4561 agggccccgg acacgtcctg atcacctcac gcaaccccaa ctggcgccgc ctggcccacc
     4621 cgacggcact cgacgtgttc tcgcgggccg actcgctcgc gtacctcagg acccggatcc
     4681 cgggcatccc cgaggcacag gcggacacgc tcgcgcagga cctcggtgac ctaccgctgg
     4741 cgctcgccca ggccgcgggc atgatcgaga ccggcacgcc cgtcgaccac tatcgacggc
     4801 tcctgaacga cagcacgagc cgcatcctgc gcgagggcga cgtccccgac tatccggtgc
     4861 cgcttgccgc tgcggtgggc atcgccgtcg agggcctcga cgccaggcac cccgacgcga
     4921 cggcgctgct ccggatcgcg gcgttcctcg ggcctgagcc gattcccacc gagtggttgg
     4981 tgaacgcgcg gccgcggttg tccacgatcc cgggagatcc ccacgacccg ctgtggacga
     5041 gggccgcgct cgaaccgctg cgccgttatg gcctcgcccg gatcgacgga gaggccctgc
     5101 agctgcatcg cctgacccag gccgtcctgc gtgaccaggt cgacccggcg caggccgagg
     5161 cgatccacga cgacgcggcg gccgttctgg cagccgtcga gccgggggat cccgaaccgc
     5221 cggccaactg gccgatctgg gcgaacctga cttcgcacct ctggtcgcag cacctcgacg
     5281 tcacccgccg gcccgagctg cgcccggtgc tccgcaacgc ggtgaacttc ctgatccgca
     5341 gcgcccagcc gcggaccgcc gccgagctcg ccgccaccct gcgagaggcg tggaccgcgg
     5401 agtcgggccc tgaccatccc gacgtgctga cctgcacgca gtacctcggc cacgcgacat
     5461 cggacctcgg cgacatccgg gctgcccgac cgatcatcga ggacgccttc gtacgtcgcc
     5521 gccggatgct gggggacgac gaccccgaca cgctgcagtc cgccaacgac ttcgccgcga
     5581 ttctctccgc cctgggtgag tttcaggagg cactgcgcat cgacgaggac accttgaccc
     5641 gtcgacgccg cgtcctcggc gaggagcacc ccaagaccct tcagtccgca ggtaacttgg
     5701 gcgcagcgct caccgcactg ggtgagtacg tcgcggcacg cggcacgcat gagggcaccc
     5761 tcgcccgccg ccgacgggta ctgggcgacg gccatccgga cacgctccgg tccaccttgg
     5821 gtctcgccga atccctgcgc ctgctcggcg acgtgaccga ggctcgacgg ctgcaggagg
     5881 agactcaggc ccgatgccgg agcacgctcg gcgacgacca cccgctgacc ctcaacgctg
     5941 ttcagggcct tgccgccacc ctgaacgaca tgggcgaata cggcaaggtt cggagcatgc
     6001 tcgaggacgt catcgcccgg cgtcgccgtg tctccggcgc tgatcacccc caagccgtca
     6061 aggccgcgta tggcctcgcc catgccctga acgcgctgtg tgaacacgaa gaggcccgcc
     6121 gcctgctcgc ggacgtcctt gcctgggagc gtcgcgttct ggggccggat caccccgaca
     6181 ccctgaagtc cgcgcacgct ctctccgccg ccctggacgg gctgggtgac cacgcagaaa
     6241 gccgtcgcct gctcgaggac acgatcgccc ggcgccgccg cgtcctcggt gaggaccacc
     6301 aggagaccct catatcgact cacaacctcg gcgtgacgat gtgcaatctg cgctccctcg
     6361 cggcgggcgc gaagttgctg gaagacgtac gcgcccgtca gcgccgaact ctcggcgacg
     6421 gccatgagga cacccaggcc accacccgat ccctcgcagc ggcctaccgg cagatggggc
     6481 tgcaccgcaa ggcgcagaaa ctgacgccga agaaatccac gaagcgtggc ttcggcagaa
     6541 agtcccgctg atcacccgcc gaacggcgcc ccggtcacca cggcaaccac cacggccccc
     6601 gccccgaacg ccccttcctc cgccaacgtc acgagcccat acagcaattt ggcgacatag
     6661 agacgttcca ccggtacccc atgccgttcc tcgaagtcct cggcgaaggc gtcgagcgcg
     6721 ggtgtcgtgc gggcgtatcc gccgaagtgg aaccgctcgt ccagccgcca gtcaccgcgc
     6781 ggcccgccga acgcctcggt ctgcagccct cgtacgtcat cggcaaggaa ggcccccttg
     6841 aggacgggga tgccgagggc ctgctggccg gggtcgagcc cggcggcgag gccggccagt
     6901 gttccgcccg tgccgcacgc gatcgcgacg acgtcggcct gcccgcgcag ctcctcgccg
     6961 agggcccgac acccccgtac ggcaagggcg ttgctgccgc cttccgggac gacgtacgcc
     7021 tcctccgctc ccgccgcgcg caggatggcc gcctgcgttt ccgggtcggt cttgcggcgg
     7081 tacgtcgatc tgtcgacgaa atgcagccgc ataccgtcgg ccacgcatcg cgcgagcgac
     7141 ggattcagtg gccgttcggc cagttcctga ccgcgcacca cgccgaccgt gggcaggccg
     7201 aggagccggc cggcggcggc ggtggcgcgc aggtggttgg agtaggcgcc gccgaaggtg
     7261 acgatcgggc gaccggccgc ggccgtcagg ttcggcgcga gcttgcgcca tttgttgccg
     7321 atcagctcag ggtggatcag gtcgtcgcgc ttgaggagca gacggatgcc acgacgcgtg
     7381 aaccgctcgt cggccgcctc ctgcaagggg gaggggagcc gagggtggag ggcggtgggg
     7441 tcggggctgg tcacctggcc attgtcgccc gggccccacg ggttgggcac ggcagccctg
     7501 tctgcgatgc tcccgcaccc gcactgcccc ggttgcttcc gcacccgtcc gtaactcgtc
     7561 ctacttcagc cgctcccgga tccgctcccg catccaggcc atcgtgaacc cccgcggatc
     7621 caccttcccc ggctgccact ccagatgccc gatcaccgac cgctccgtcc agccgtgatg
     7681 gcggcagatg gccgccgaga cccgctcgat cgcgtccagt tggggctccg gccacgggtc
     7741 ctgtccgtca cccaggttct cgcactcgaa gccgtagaag tggcggttgc catcggtgtt
     7801 ggcctcgttg tcgggaggca gggccttctc cgcgatgacc gcgcgcagta cgtcgtcgtc
     7861 gccgaggccg gcgtggttgg cgcggccgta gccgacgagg tggaccctgc cgtccttggt
     7921 gatgacgccg tggcacagcg ggcccggcag cccttcgtag ccgttgcggc agagttccac
     7981 cgtgtgtgcg ctgccctcgg tgaccgtgtg gtggatcatc acgccgtgga cggggcccca
     8041 cggaccgacg tggttgcggt tgtggtgctc ccagtcgccg acctcgacga ccgtggcgcc
     8101 ctccgcccga agtctctcca ggaatctgct cgcggacatg ggtgaggcca tgaccgcctc
     8161 cttcgtgccg tgcgtcggcc gccgtgcgcg gccgcctcgt atcggtgact taccgaaaac
     8221 gggcagacgg gactcctcga gtcgtacggt gtgcgagtca tttcggacaa tcgccgtggc
     8281 acggatggga cgggcaccgt gcttccacgg gtggacaaga gccctctatt tgcccagtca
     8341 gccgtgatcc attcccgctc tttcgtgtaa tagcaccagc acactccgcg atggaaggct
     8401 cggtcgtgca gatcgcgatg cgtggcgcca gatcggcgtc ggggcatgac cgggagggca
     8461 gttccttatg tcggtaggcg aagaggtccg cactgagcag gacaagccgc agcagagtct
     8521 cggcacggcg gcggcgcgga acctggccac cacgaccaag tccgcacccc agatgcagga
     8581 gatcagctcc cgctggctgc tgcgcacgct gccatgggtg aatgtgcagg gcggcacgta
     8641 ccgggtgaac cggcgcctga cgtacgccgt gggggacggc cggatcacgt tcgtgaagac
     8701 cggcgaccgg gtcgaggtca tccccgccga gctgcgcgaa ctgcccgccc tgcgctcgta
     8761 cgaggacgag gacgtgctgt cggagctcgc ccagcgctgc caacagcggg aattcgcggc
     8821 ggggaacctg atcacctcgt tcggcagtcg taccgacgag gtgtatctgc tggcgcacgg
     8881 cagggtggag aagctcggca gcggaccgta cggggaggac gagtccctgg gcgtcctcgc
     8941 cgacggggcc tacctcggcg agcaggcgct gatcgacccc gacacgatct gggagtacac
     9001 ggtccgcgcg gtcaccgcgt gcacggtgct cgctctgcgc cgccaggact tcgagcaggt
     9061 cgcggagcgc tccgactccc tgcgcgagca cctcgaacag ctacgggcgg cccccgagca
     9121 gcgcaccaac aaatacggcg agaaggagat cgacctcgcc gccggccaca gcggcgagcc
     9181 cgacatcccg cacaccttcg tcgactacga ggccaggccc cgtgagtacg aactgagcgt
     9241 cgcccagacc gtgctgcgca tccacacgcg cgtggccgac ctctacaacc agccgatgaa
     9301 ccagaccgaa cagcagctcc ggctgaccgt ggaggccctg aaggagcgcc aggagcacga
     9361 gctcatcaac aaccgcgagt tcgggctgct caacaactgc gaatacgacc agcggctcca
     9421 gccgcacgac ggcgtgccca gccccgacga catggacgag ctgctctgcc ggcggcgcgg
     9481 caccaagctc ttcctcgccc acccgcgcgc gatctccgcg ttcgggcgtg agctgaacaa
     9541 gcgcgggctg gtccccgaga ccatcgagat cgccggcaac cgcatcccca cctggcgcgg
     9601 tgtacccatc tacccctgca acaagatccc ggtcaccgag gcccgtacga cctcgatcat
     9661 cgccatgcgt accggcgagg cggagcaggg cgtcatcgga ctccagcagg ccggcatccc
     9721 ggacgagatc gagccgagcc tgtcctgccg cttcatgggc atcaacgaac aggccatcat
     9781 caagtacctg gtgacggcct actactcggc cgcggtcctg gtaccggacg ccctcggtgt
     9841 gctggagaac gtcgagatcg gtcgctggcg gtgacgctcc ccgtccgaac gctcgtcgct
     9901 cgtacgtcgt gtcccgcgcc gcccgcgtgg gtacatcctc ggggtaggcg cccagccgta
     9961 gcggaagggt caccgtccgc cgactctccg aggcgatgcc atgggtgagt tcatgacgga
    10021 gacggagcag cgtcctgccg gggcgcggcc gtccaccgag acgctcgaaa ggcggaggcc
    10081 gatcgcgatc gacatggacg gcgggagcgg ggcgagtccg ccggacgggc cggaggcggc
    10141 gctgatcctg gagcgtgtcc gggcgtcggt cgaccccgaa ctgcgcgccg ccgtcgagtc
    10201 gttgccgccc tccatgcgcc ggatcgcgcg ctaccacttc ggctgggagc acccggacgg
    10261 caccccggcg gcgggcaacg cgggcaaggc gatccgtccc gccctcgtcc tcaccgcggc
    10321 cgccgcactc ggcggaccgg cggcacgggc ggcggcggta caggccgcgg tggcggtgga
    10381 gctggtgcac aacttcactc tgttgcacga cgacgtgatg gaccgggaca ccacccgtcg
    10441 gcaccggccc accgtatggg cggtgttcgg cgacgccgac gcgatcctcg ccggggacgc
    10501 cctccaggcg ctggctctgc ggctgctcgc cgaggacccg cacccggcgt cggcgcccgc
    10561 cgccgcccgc ctcgcggcct gcgtcgtgga gctgtgcgcc ggtcagcacg cggacacgtc
    10621 gatggagaag cggggccccg gtgacgtcgg cctcgacgag gtgctcggca tggccgaggc
    10681 caagaccggc gcgctgctcg ggtgcgcctg tgccctcggt gcgctgtacg cgggcgcggc
    10741 ggacgagcac gtggcggcgc tggacgcgtt cggccgtgag tccgggctcg ccttccagct
    10801 gatcgatgac gtgatcggca tatggggcga ccccagccgc accggcaagc cggccggcgc
    10861 ggacctcgcc gcccgtaaga agtccctgcc ggtcgtcgcc gcgctgacct ccggcggtcc
    10921 ggcggcggcg gaactggccg cgctgtacga aatgccgtac gacaaggagg acttgcaggc
    10981 gaccgcgctc gccgtcgagc gagcgggtgg ccgcgactgg gcgcaggccc aggccgccga
    11041 ccggatggcc cgcgccatgc aggaactggc tcgcgcggtc ccggatccgg agcaggcggg
    11101 cggactgctg gccctggcgg agtacgtgac gcggcgcagc aactgagggc cgtggcagcc
    11161 gatggccgag tcgctcggtc gcggcagccg atggtcgtcg agactccgga gccatcgggg
    11221 ccgtacggtt cctgaccccg tacggccgcc gggcggctcc ggaccggcgg gtcccgcaca
    11281 tccccacggt gtgcggggcc cgtccccgtg tatcggactg tgtaccggac agatctcgac
    11341 aaagtcgccc cgcggacggc acgcccgctt cgatcgccct acgatcaagg ccggttgacg
    11401 tgaaggggcg ggtacacatg ggcgtgcgga tccggacggc gggcgagggg gaccgggagc
    11461 tggtggtccg gttgctggac gcggccttcc aggacgatcc ggtcagcggc tgggtgttcc
    11521 cgggcgagga gcaccgccgt accacccacc ccaagctcat ggccgcgttc accgacatcg
    11581 tgagcgccgt cggccgtatc gacgtcaccg aggacggcac ggcgtgtgcg ttgtggatat
    11641 ccgtgcctgc cgtcgagcag gacctggacg acgaagggcc cgctcggctg cgcgcgcagg
    11701 tcgacccgga gaacgagcgt gtcgagctga tcggccgcct gacagccggt atccatcctt
    11761 ccggccgcgc ccacgaatac ctgtggatga tcgccgcggc acccgggcac cagggcgagg
    11821 gtctcggcac cgcgctcatg aactcggtcc tcgaccgctg cgaccgggac ggactgcccg
    11881 cctacctgga ggcgagcagc gaccgtagcc ggaagctgta cgagcgcctc ggcttcgaac
    11941 tccagggccg tcccctcgac ctcccggacg gcccccggat gtggccgatg tggcgcgagc
    12001 cgcgcggctg agccaccgcc cccgccctcc ttaccgttcc ggccgccgcg ccccgtgccg
    12061 ctccgggccc tgctgggcat accgctcaga ccgccgggcc ccaccgctcc ggcccccgct
    12121 gccactaccc ctccggtacg accgtctcca cgatccgctc gaccaggccg tccggcacgc
    12181 tgaccccggg cagggtgccc tccagcacgt ccggcagtgt caggtgttcc aggagcagcc
    12241 cgagcatcgc gagatagagc acggtgacga cctcgtcgcc gccaggcagc ccggcgttcc
    12301 ggtggaactc catgccctcc tccaggtcgc cgcgcaccga cttggtgaag gaggagcgca
    12361 gttcggggcg ccggccggcc tccaggcgca tctccagcag ggccagatag cccgtgcggt
    12421 cgcgggtcgc gcgggccatc aggtcgtgca tgaaggcggt gaccagggag cggtccttcg
    12481 gccgggtcag cagcccggcg atcacctcgg ggtcgggcgc cagccgcaag tgcagccggg
    12541 cgtcgatctg gcggagcagg tcgtcgcgcc cggtgaagta gttggaggcg gtgccgaccg
    12601 gcaccccagc ctcggcgtcc accgcgcgga acgtcagccc gcgcgcaccc tcccgggcga
    12661 gcacctcgac gcccgcgtcg acgagcgcgg cccgccgctc cggattgccc gccattcgga
    12721 gtcctctctc tcacttccat ccggtcccca aaataccctt gcgaccacta caagcgaagt
    12781 actacaactg aagcactaca accggagtgg ttgaccagcc tacgaaaaga gaccggcttg
    12841 cgaaagctca cctacttcat cgcctgctcg ctcgacggct tcatcgggga cccgagcggt
    12901 gacgcgtcgg cgatgctcgc cttcgtcgac gaggagtacc tcgcgttcct caagagcgaa
    12961 tacccggaga ccctgccgac ccatggccgt cgggcgctcg gcctcgacgg cctggagaac
    13021 aagaggttcg acacgatcat ccagggccgc ggcagctacg acctggcgct gaaggagggc
    13081 gtcaccagcc cgtacgccca tctgcgcgaa tacgtcgcct cgcgcaccct gacggagtcg
    13141 cccgacccga acgtcgagat catcggcggc gatctggtcg ccaaggtgcg cgaactcaag
    13201 gcggaggacg gcgagttcgg catctacctc tgcggaggct cgcagatcgc gggcgaactg
    13261 ctcgacgagg tcgacgagct cgtcatcaag tcctacccca tcgtgtacgg cgcgggcatg
    13321 ccgatgttcg gctcggacct cgccgtcacg gagttcaccc tcgacgcggt gcgcagcttc
    13381 ggcaacggcg ccgtggtccg tacgtacagc aggaagcgct gagcggtttc ccgccctacc
    13441 ctgaggacat gggcagcgaa gagcacgtct gtcccgactg cggacagccc gtcgacacgg
    13501 tcgtcaggcg ccacaagacg ctgggcgcct gggtccccac atgggtggcc ggcccgtgcc
    13561 ggaaccccga gtgcagcgcg tacagcgagg gtgacgccga gcacgaggaa aggcacgcgc
    13621 gcgagcgcaa gcccgagccc gagtccgagc gcaagcccga gcaacctgag gcacccaccg
    13681 cgaaaaaccc ctgaccccgt gtcgagaatc ccggcccggc tccgacgtcc cctgtgagag
    13741 ccgcccgaca agggtggccc gagccgacgg aagcagaagg agcggaccga tgaagtacct
    13801 ggtcatggtg cagggcacgc aggcggacta cgaggcgatg cagggcaagg cgtccgagca
    13861 ctcggtggcc tggagccagg aggagatcca ggcgatgtac gcctacatgc aggccatcaa
    13921 cgacgacctc gccgagaccg gcgagatgat cgacgggcag ggcctggccg agcccgcgaa
    13981 ggtccggcac gtcaccctgg gcgacgacgg caaggcggtg atcaccgacg ggccgtacag
    14041 cgagaccaag gagctgctgg ccggctactg ggtgctggac tgcgcgagcc tggagcgggt
    14101 caccgagatc gccgagcgcg tcgcccgctg cccccagccc gccggggccc ccgtgtaccc
    14161 ggtggtgatc cgtcccatcc tggacggcgc cggagactgc tgagccgccg atggccggcc
    14221 cgaccgagac cgaggacctg ctgcgccgcc acgcgccgca ggtcctcggc gcgctggtgc
    14281 ggcggtacgg ccacttcgac accgccgagg aggccgtaca ggaggccctg ctcgcggcgg
    14341 ccgagcagtg gccgcgggac ggtgccccgg acaatccgcg gggctggctg atcaaggtcg
    14401 ccgcacgccg gctgaccgac gccctgcgcg cggaggagtc gcgccgggcc cgggaggaga
    14461 aggtcgcggc gctgacaccc cgggacgcct tcacggcacc ggcgccgggg gcggaccgcg
    14521 cgccccgcga ggacgacacc ctcaccctgc tcttcctgtg ctgccacccg gacctgcccc
    14581 cgcccgccca gattgccctc accctgcgtg ccgtaggcgg gctgaccacg gcggagatcg
    14641 cccgcgcgta cttggtcccc gaggcgacca tggcccagcg catcagccgg gccaagcaga
    14701 aggtccgcgg tgtgcggttc gggcgtcccg acaactggga ggaccgtctg cccgcggtcc
    14761 tgcagaccct gtacctgatc ttcaacgagg gctatacggc gacctcgggc gcgagcctga
    14821 cgcggcggga actcgccggc gaggcgatcc ggctgacccg cgaggtgcac cggctcctcc
    14881 ccgagcacgg tgaggcggcc ggcctgctgg ccctgatgct gctcaccgac gcccgccgcg
    14941 acgcgcgcac cggcccgcac ggcgagctcg tccccctcga cgaacaggac cgcgaccgct
    15001 gggacaaggc cgccatcgag gagggcgtcg ccctggtcac ccgcgctctg tcgcagggcc
    15061 gcgccggccc gtaccagctg cgtgccgcca tcgccgccgt gcacgacgag gcgccctctg
    15121 cagaggagac cgactggcgg gagatcctcg ggctctacga cgtcctcgtc cgcctcgttc
    15181 ccggacccgt cgagcggctc aaccgggcag tggccgtcgc catggtccag gggccgcggg
    15241 cgggactggc cgaactggac gcgctggagg acgagttggg tgccgggcac cggctggacg
    15301 cggtccgcgg tcacctcctg gagcgggcgg gcgctcacga cgaggcccgc gccgcctacg
    15361 aggccgccgc cgccaagacc ctgagcctgc cggagcagcg ctatttgcac gcgcgggcgg
    15421 cacgactgag gccatagcgt gggcccatgc ccgaacagac gtacatcctc cacatcaccg
    15481 agcgctccct gtgggacgcg gcgcgcgagc acggcacgta cgagatctcg acacgtggcc
    15541 gcacgctccg ggaagagggc ttcatccact gctcgacccg cgctcaactc ccgtccgtgg
    15601 cagcctttct gtacggctcc tacgacggcc ccgaggagct cgtggtgctg gtcgtggacc
    15661 ctgcgcggct cggcgtgccg ctgaagtacg aggcgccgga gcccgggggc gaggagttcc
    15721 cgcatgtgta cgggcccatt ccggtggacg ctgtggtgga cgtggagccg tgggggtgac
    15781 gtcgggccgt cgcgggttat ggcgatgggt cgtggcggtg tgggtgatcg tcgtggccgt
    15841 cgcgggcggg gcgacgctgt ggttgcaggc ctcggcggag ccgccggggc cgtaccgctg
    15901 ggaggaagcc agtcctacgc cgtcgcttcc gcaagggtgg ccgtcggcgt gcccgagccc
    15961 ctcgcgcgac gagaacggcg cggcacaact cctctgcttc gtcaggacgc gctagcgccg
    16021 gtcagcccgc ccgtctccgg gtcccgcgcc gtcaggcagt acacgccgcc cgccggatcg
    16081 cgcatcaccg tccagtgggc accctgggcg acgaacgccg cgcccagttc ctcgtgccgg
    16141 gcgcgggccg ccgcgatgtc cgcgcaggcg aggtccaggt gggcggagcc cgaacgcccc
    16201 tctccgggcc gctcctctcc gagccgctgg agcaggatgc gtacgggcag cccggccgga
    16261 ggcctgagca catggaactc gggtcgggag ccgggcgccg acgcccagcc ggccaacagg
    16321 tcgctccaga aggcgacttc ggtgtcgtac agcgacggcg gtacgtccag gcagacctga
    16381 tcgagccggc tgccgcgcac cacgggcggc cgcaccgact ccccttgcca gggcacggca
    16441 cagaacaact gcccggcggg cgaccgcagt acagcccacc cgtcgtgctc ggcggcgagg
    16501 cccgcacccc gctgaagggc cgacttcacg aattccggta cgtcgtccac ggcgaagtcg
    16561 agatgcgcgc caccggcgcc cgagccgacc ccctggacct tcacgcaggc gtcggcctcg
    16621 ccgcccggca gcagggtcac gaactccccc tgctcacccc ggaattcgga cagccgtgtg
    16681 tccgtcaccg cagcccagaa ggcatgggcc cgggcgaagg actcggcggg gcggtcgacg
    16741 aaggcgtagg tccagcggat gctcatgggg cgatcgtaga tccgccggcg cggtggcggg
    16801 tctgcagcag ccgtaggggg ctcctcggtg cctcaacgtt caccacggcg gctttgcagg
    16861 acccttacca atcgcgcgtc ggcccctggg acacgctttg ccgtgggttc tccgcgaatt
    16921 ggcccgagct tgtttgcatt ggggaatgga ccacatcacg ttcctggtgg cggtcgtcat
    16981 cgtgacggcc ctcgccttcg acttcaccaa cggattccac gacacggcga atgcgatggc
    17041 cacctccatc gccacggggg cgctcaaacc gaagacggcg gtactcatca gcggcgtcct
    17101 gaacgtcgtc ggtgccttcc tgtccaccga ggtcgccaag acgatctccg gcggcatcgt
    17161 ggacgacaca ctcgtcaccc cgggcatgat cttcgcgggc ctggtcgggg cgatcctgtg
    17221 gaatctgctc acctggctgg tcgggctgcc gtccagctcg tcgcatgcgc tgttcggcgg
    17281 gctgatcggg gccgtctggg tgggggcggg gtctcatggc gtgcacttcg acaaggttgt
    17341 cgagaaggtg ctgatcccgg cggtggcctc gccgctcgtg gcgggcgtcg cggcgctgct
    17401 ggcgacctac ctggcgtaca agctcacctc tcgcgcccgt aagcagtccg tcaccaaggg
    17461 cttccgcctc ggccagatcg cctcggcctc gctggtctcc ctcgcccacg gcacgaacga
    17521 cgcgcagaag acgatgggcg tcatcacact gaccctgatc tcggcgggcg cactcggcca
    17581 cgacgcgggc ccgccggtgt gggtgatcgc ctcggccggt ctggccatcg gtctcggcac
    17641 ctacctgggc ggctggcgca tcatccgcac gatgggcaag ggcctgacgg agattcagtc
    17701 cccgcagggc ttcgccgccg agacggcgtc cacgacggtg atcctgacct cggcccacct
    17761 cggcttcgcg ctgtccacca cgcaggtcgc ctccggcagc atcctcggcg ccgggctggg
    17821 ccgccgcctg gcggaggtcc gctggggtgt ggccgggcgc atggtcgtgg cctggctcgt
    17881 caccctgccc gccgccgcgc tggtcggtgg cgtctcggcg ggcgtggtca agcacggcgg
    17941 caacctcggt acggccgtgg tcgcgctggt cggtgcggcg gtggccgccg gcatcgtgct
    18001 cgtctcccgc cgcaacccgg tgtccgcgca caacgtcaac gacgcccacg aggtcacgat
    18061 ccgcagcacg gaggagccga cgacggtcgg cacggccgcc tgagacatgg ccgcctagac
    18121 acggcagcct gaaacaaggg gagttcacac catgaacctc gactggaccg cactcggcca
    18181 ggtcgccgcg gtgagcctcg ccgtcacggt ggccgtggtc accgtcttcg ccctcggcgt
    18241 gctgggcctg gcccgctacg aaagggcccg cgaggagggc gcgggcacgt ccaccgtcgg
    18301 cggcgcccag gccgggctgt gcttcgtcgc ctgcgcggcg gtggtggcgt acgggatcta
    18361 tctgatcgtg ccgcagttcc actgacgttc gtccgacgtt cgtcgaaggg gcccggccgg
    18421 aggaccggcc gggccctatg cgctgttgtc cgccgctccc agccgctcgt acgccgtcac
    18481 acgccgcccg cggacctgta cgtccgccac caccctgaag tgctccttca gcacggcggt
    18541 cttcatcttg tcccgctccg ccgacaccgg ccgtgccacc gcgggcacat cagtgaccag
    18601 cagtattcgg cgctgtgcca gcatcgcgcc acgtatccgt gccggagccg cctcctcgcc
    18661 cttcagcgtc cccgacgcca cagggctttg tgccagcgct atgtcccgca gcccggcgaa
    18721 gtcgtcgggg cagaccaggg cggtgtcgcg ccgggccgcc ggtatgaaca ccaccgcgtc
    18781 cccggactgc ttcagccgcc gcacgtccgc cgccaccgcc atcacgtcgt ccacccggct
    18841 ggccggagag cgcttggcca tcgactgcgg caacagcgcc acgaccgcga cgaccaccac
    18901 caccgggacg agccacgccg acgacctcgg aaaccgcggc cggaccgccc gtacggccgt
    18961 gcccagcgcc gtgccgatca gcagtgccag acccagcatg ctgaacagga catagcggtc
    19021 caggaacagc ggccggacca gggagaggcc gacgaggccg agctgcggca ccgccagcag
    19081 cggcagcccg acggccgcca cggacagccg acccgctcgc ggccggtcca gcagggcacc
    19141 gagaccgccg atcgccagca ggaccgccgg gccgatcagc atgtgccagg tcagcggcgg
    19201 gatccaggag acctggtcgg actggcgccg actgaagagg atcaacggca gcacagccac
    19261 cacggcggtc accgcggcca ccgcccagcg cgtccatgtc cctcgccgtg cccgcgtcca
    19321 gagcagggtc gccaggtgcg cgggcaggat cagcagcgac agccagttca gcagcccgca
    19381 caccgccacc gtcccgccgt acgccgccca gtgcaccgct cggccacgcc cgtcgaggac
    19441 ggtcaccagc aacagggtgg agatgccggc cccggccgcg atcaacgcgt acgggcggcc
    19501 ctcctggaga tagaactgca cggccggaag cagcccgaac gccagccctc ccgccaggcc
    19561 cgcccaggcc ccggccagcc gcccgccgat gaccgtcacg caggccgccg ccaccgccat
    19621 ggccagtacg gagggcagcc gcagggtcgt ggtgccgggc ccgaagcact cgaagagcgc
    19681 gtgcatcagc aggtagtaga ggccgtgcac ggcatcgacc tgccccagca tgtgccagat
    19741 ctcgccgacg gaccgccggg ccacctgcca ggtcgcggcc tcgtcccgcc acacgctgtg
    19801 ctgccgggac agcccccaca gaccgaggcc aagggtccac agcaggggta tcggccagag
    19861 gggcgggcgg cggcgcaggg gtggctccag ggggatcggc attccgggga tcgaaattcc
    19921 gtacggcggg ggacaggcag ccgccgggtg atggtcccca ctcgcccgct cgtcgcagag
    19981 cacgccgaac ccccgcctcg gccgcgctgg tcgagacggg atcagatttg agcgttgctc
    20041 gcttcccccg tgaacgcagc aaaacctacg ggacggggcg gatccgcggc caccgtccag
    20101 ggcgtgaaca caatcaccgc gaatgaaggc aaccttgagc cccctgaacc ctctccgagg
    20161 cagtcaccag agctcggtct cctgctgatg ttccacgcga cgttacccgt ggggaacctc
    20221 agatctaccg caaaccttgg cctgcgtcgt tgccaggcga accggtccgt tgcgagtgtc
    20281 ggagccgccc cccgcaagat cctcatcggt gatccccctc tccccgaggg gcgaatcgga
    20341 ggtttgatga ccgcccgccg tgccctggtg gccgccgcgt ccgcgacggc gctggccctg
    20401 ccgctcctgc tcccccacat ggccaccgca tcctccccgg cggcggcccg agaagcgtcg
    20461 tccgggctgg agccgcccgc gaaggaggca gtcgccaccg gcagcggcgg cgccgtctcc
    20521 agcgtgaacc cgtacgcctc gcaggccggt atcgaggtgt tgcggcacgg gggcaacgcc
    20581 gtggacgcgg ccgtcgccac cgccgccgcc ctcggtgtgg tcgagccgta ctcggcgggc
    20641 atcggaggcg gcggctactt cgtgtactac aacgcccgca cgaagacggt gcggacgatc
    20701 gacggacggg agacggggcc ggcccggatg cggtcggact cgttcgtcga cccgtcgacg
    20761 ggcaaggcga tcccgttcga cgaggccgtc aactccggcc tgtcggtggg tgttccgggc
    20821 accccggcga cctggcagca ggccctggac gagtggggca ccgtgtcgct gggccaggcc
    20881 ctgcgccggg cgacgcgcat cgccgacgag gggttcgtcg tcaacgacga gttccgcgcc
    20941 cagaccaagc tgaacgaggc gcggttccgc gacttcagct cgacggccga gctgttcctg
    21001 ccgaacggcg aactgcccgt ggtgggcacc cgcttccgca atcccggcct ggcgcgcacc
    21061 taccgggagc tctcccgtga gggcgtggcc gccctgtacc gcggcgacgt cggccgtgac
    21121 atcgtgcgga ccgtccagaa cccgcc
//
