LOCUS       NZ_RQJW01000004        26329 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces cyaneus strain CGMCC 4.1671 Scaffold3_1, whole genome
            shotgun sequence.
ACCESSION   NZ_RQJW01000004
VERSION     NZ_RQJW01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces cyaneus
  ORGANISM  Streptomyces cyaneus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 732681)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Streptomyces sp. nov., a novel actinobacterium isolated from a karst
            cave sample
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 732681)
  AUTHORS   Fang,B.-Z., Han,M.-X., Jiao,J.-Y., Xie,Y.-G., Zhang,X.-T., Liu,L.,
            Zhang,Z.-T., Xiao,M. and Li,W.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-NOV-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135 Xingang West Road, Guangzhou, Guangdong 510275,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 03-OCT-2018
            Assembly Method                   :: SPAdes v. 3.6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004028635.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 03:28:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,717
            CDSs (total)                      :: 8,635
            Genes (coding)                    :: 8,413
            CDSs (with protein)               :: 8,413
            Genes (RNA)                       :: 82
            rRNAs                             :: 6, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (5S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 222
            CDSs (without protein)            :: 222
            Pseudo Genes (ambiguous residues) :: 0 of 222
            Pseudo Genes (frameshifted)       :: 77 of 222
            Pseudo Genes (incomplete)         :: 187 of 222
            Pseudo Genes (internal stop)      :: 12 of 222
            Pseudo Genes (multiple problems)  :: 50 of 222
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:58:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 269965
            Orig. end                         :: 296294
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RQJW01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26329
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26329
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26329
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16329](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16329
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    222..236
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    complement(340..355)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     misc_feature    complement(2020..2033)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            complement(3007..6378)
                     /locus_tag="EHO50_RS16585"
     CDS             complement(3007..6378)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EHO50_RS16585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_128430924.1"
                     /transl_table=11
                     /translation="MANVEVGTDVVELTLPDVLRRTQAGELPVPVQNPALLPLADLDPE
                     VFERLIAEIVSRRNNIGVQFYGRRGQKQYGLDIVERETPSARVLYQVKRFEELTGAKLR
                     EAVQEYSGPPRPPKYRGEARRFSPYRFVVVTSAGLDRDTENVDTLEELQTSYAGDLEID
                     AWGAETLSRMLRDMPHLVYAVFGPQWAKTYCGYKPSPSDLAAPKSLGLVEDPIAVLQLD
                     ALEADATQAEPIDPLKASQLFGRVAEGLLQGNFPGHATEMRRRQAQAAQAGGDHESAFR
                     VLFDLALQRVLSGSTSTVRSLLSNLESLAPHRSDVERAELSALTCVAFWYGEGSNLDDG
                     VSALRTLTAARAPRTGLLSCLLLEQAVVDGLYDFVPARSVVATTDEQTATRLVELREMA
                     SAATSTDVEIRARLRCAVADASLTAAASPDEVDAAYRRAVDDALAGRFLHVRGLVASRA
                     AYAFATHGDFERADSYWRQAAIASSEESYYGDALGAMWSSRLLEWDKGRFELPGLQHIA
                     NSLPNRQRLLAASYDPELEAMQAARGNRLPDAFESTRRHLWEHRLAGHLQGEILALKLF
                     GEVLEASEHPADALECYIRAGEASQARKVAQKIPDTVDVSMWVGSPLRRRRAAAVQVIG
                     AQSSTIPDNNVPEVIERLLEVAEGVWQAPAFQVRPERDALDGIARFGMRIPETAVDRVL
                     TMAEPALKNSTRISDVIANLLVQTYWAVESRRQDVAKAIGRMLQLPQPHPELWNLVEGI
                     PKEAREPLLPVVTTLAEEGQQSAIEVLAGWGVATQPVQLAARRACAALLRRRVGVPRSM
                     TAMGTQQSTTVNLLLVLLTAENLTHFPPEELTSKKARPAGGVLAVHQTLSSSDSPPPTD
                     TEKNSENETLDNATLIAAGPPANLAAAVASHMTAIAEDSQQGAAFRAETVRALRYLVPK
                     VPKATARDLALRLIEVHRAPHYTQTDKLEIDSNHSLSRFKLNMGGDQLPVLALVASSEM
                     FAASCQGNSKMTPEEQSFAQEAMASALPLLREGDRRVQRLGASTVVAIASSIREFAEYA
                     IGLVFHNDEIVRARGAAHGPVTPEMIAKLAEDPSAEVRAAVASRGNELSSVVRDKLATD
                     THLRVRRTLERSTSTS"
     misc_feature    6462..6471
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(6490..7029)
                     /locus_tag="EHO50_RS16590"
     CDS             complement(6490..7029)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825822.1"
                     /locus_tag="EHO50_RS16590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_181449632.1"
                     /transl_table=11
                     /translation="MTTAPALELRTFITLDSARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHGAEPGFTAVLAYADGHPVGYAYGNTIEHGDRYWQRTSPAPAEKYTERPAVALK
                     EIGVRPTWRKTGTARRIHDALLATRDEPYVTLMVNPAAGDGKVHALYKSWGYEDIGQSQ
                     PSPASPVLNVMIRGVD"
     gene            complement(7026..8309)
                     /locus_tag="EHO50_RS16595"
     CDS             complement(7026..8309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="EHO50_RS16595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_128430925.1"
                     /transl_table=11
                     /translation="MDTTRNTVLEAWMTEHGYSSNSLAEAVNRAIERLTGRPGGLDGSS
                     VRAWKAGRVTWPKSAARRALEDVTGLPAVALGFVPRGRPSSTPAPLQQEDPDMKRRTLV
                     GSIAAAAAAAAAPGTASPRRIGMSDVNRLNKRFAEIIASDHRHGGQLGIEQRAAALADE
                     ALNLQNAGSATQRVRSNLYASAAAFRSSAMWAAIDGRRYDIAMAHMREAQALAEMSGDQ
                     AIKFRIWSHAGTMYRHMGRPADAFAANDVARNLHLTRRDPLFASLGLARQGAIHGTAQD
                     RTGTRRAFEQAQDAMLRADPTDYRPVWMLAFYDQAELDSLALSAHLALGDYSTAEYHAH
                     RCLSALRPHMIRSRAITTTRLAHAQLAQGAPDAATATAMKVPAEAATQHARVTRMLQEF
                     GAALRATAPGSSTVQTWTEHTATWRMAA"
     misc_feature    complement(8082..8084)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8097..8099)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8551..8997
                     /locus_tag="EHO50_RS16600"
     CDS             8551..8997
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000003.1"
                     /locus_tag="EHO50_RS16600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_128430926.1"
                     /transl_table=11
                     /translation="MTSLRTPVAALSVGHPTYSQTFPCKPSTAEIGRGLVRDVLGVWHL
                     DGLAHRAALIVTELIANACRHTPCSEIRLTVARPDATRLRVGVVDREPARLPMLSQAAD
                     DDESGRGLLLVDAVADRWGYDLHGSGRRPWGKEVWAELRTGGGE"
     gene            9225..9413
                     /locus_tag="EHO50_RS16605"
     CDS             9225..9413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337811.1"
                     /locus_tag="EHO50_RS16605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_019759144.1"
                     /transl_table=11
                     /translation="MEWPWITGDCWLGCGRTGVLVIWLGPVQWDGQHAPFYACEPCLDR
                     LKAQALAYFMERRPASA"
     gene            9604..9783
                     /locus_tag="EHO50_RS16610"
     CDS             9604..9783
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="EHO50_RS16610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_128430927.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 4.4e-14, bitscore:
                     47.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTDVPGRTEVRPQIPGASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     gene            10001..12955
                     /locus_tag="EHO50_RS16615"
     CDS             10001..12955
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="EHO50_RS16615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_128430928.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.7e-201,
                     bitscore: 664.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.2e-21,
                     bitscore: 70.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.6e-21, bitscore:
                     72.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWLRAVWANKDVTEALQHSSPVLAAQVGALCTAEDPALRDVQRA
                     ALSVARYLLRAQHRATPFGLFAGVATAEFGPQARADWSEEHVAVGRAGAEWLAALVARL
                     ESCPDLLERLPVVVNNTVTYRGDRLVVPFQPDVQDDRTRAVEASLALTEPVRAVLAAGR
                     LPIRFGTLVEKLQAEFPQAGPEKARQLLAELIRRRVLITGLHAPSTETDALGYLVGQLD
                     AIGAGILAPVAETVRELRAVRAGLEECATHGGRDSVAARMRDLVPGLRHHPVALDLRLD
                     AQIVLPEAVAREIERAALTLTRLSIRPYGAAAWNEYHQRFYERYGIGTMVPLADVVADS
                     GTGYPDGYPGASASARRPRVSARDDALVRLAQTAALDGRDEVILTDEQIEALDVGPDKP
                     RLPPHLEIGVRVHAASLEELQRGQFRLEVVSVSRGAGVSTGRFLSVLAPADRDALVTEL
                     ADLPAADGNTMPAQLSFPPLLPESAHVTRSPQVLPTLISLQEHRAPQDTVLTPEDLAVG
                     CDGRRMYLAVPERGHRVEAIGMHALNLHTHTPPLVRFLTELSRAQCAQVTVFDWGAATA
                     MPFLPRLRYGRTVLAPARWRLEASELPGHARPRAEWDVALSDWRARRRLPRHVHLVEND
                     RRLFLDLDEGGHRALLRRHLDRTRLAVLVEAPEPEAYGWCGGRAHEVVVPLKATRPSTW
                     PPLPAPSRARALSADQMQTPASSSVLLAALYGDPRRQDVLLSRHLPGLLEQLGNPPWWF
                     IRFRDPDQHLRVRIALPDPEAFAGTARTVSAWADELRSIGLLSDLRYPTSYREMGRWGS
                     GAAWEAAEEVFRADSRAVLAQLTQPQRPGPRTLVVAHTVAIASAFLGGTAAGMRWLIDH
                     IPPKAPAPVPRPQFIDAVRLADPSDDWAALRHVPRGDAIVSGWADRDTALARYRPHLPG
                     PDTQGIFVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARTRGRTS"
     misc_feature    10010..10012
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10346..10621
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EHO50_RS16615_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.90E-22"
                     /identifier="RREFam001.1"
                     /label="EHO50_RS16615"
                     /locus_tag="EHO50_RS16615"
                     /protein_end="207"
                     /protein_start="115"
                     /score="70.8"
                     /tool="antismash"
                     /translation="VVVNNTVTYRGDRLVVPFQPDVQDDRTRAVEASLALTEPVRAVLA
                     AGRLPIRFGTLVEKLQAEFPQAGPEKARQLLAELIRRRVLITGLHAP"
     gene            12952..14226
                     /locus_tag="EHO50_RS16620"
     CDS             12952..14226
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="EHO50_RS16620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_128430929.1"
                     /sec_met_domain="LANC_like (E-value: 2e-44, bitscore:
                     147.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHPTLGLVHAIATRLADPDTVPLGSRLLSSDRQHLAYGPPGIA
                     LLHIELAANGRGPWHRAHDWLTAASRQPLTSGPDSHPFYGVPAFAHALSCAADHLPGSY
                     QRALDAMDGQIAVDVGRRLDAAHRRIDAGRLPQLVEFDAIRGLTGYGAYLLRQDPGSST
                     MRAVLDYCVRLTEPITHHGETMPGWWTETGPSGSPDDRFPGGHANTGMAHGIGGVLALL
                     ALAARNGFLTDGHHAALRTILAWLDRWKERADGGRAWPYWVTQGELRRGRLGSSGPRRP
                     SWCYGTAGLARAQQLAALALGDTDRQSDAEKALVAALTDPEQLKATTDNGLCHGFSGLA
                     HAAARTADDAHPSTAEKLRAAIPALLAAVTPPGTDPQLMATALIQDEKGGPGLLDGAAG
                     IALALLAPSITAPPRSAWDACLLIA"
     gene            14248..16329
                     /gene="fxlM"
                     /locus_tag="EHO50_RS16625"
     CDS             14248..16329
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="EHO50_RS16625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_128430930.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.1e-28, bitscore:
                     93.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 9.3e-48, bitscore: 158.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDRWQQHNITFVQRESARRTIAERLGPALIEAEADGQLTSWWF
                     MNKQPWPLRYLADEPSPAIESLLSDLIGDGVAVSCLPCVYEPETDAFGGPEAMDAAHEL
                     FHSDSRHLLTYQPSPMHLGRRETAVLLASVMMRGAGLDWFEQGDVWAKVAALRPATNPP
                     QPERAAELAPAMRKLMTADTHSLCRLGHPLHAHEEWVTAFEQAGATLAELAGRGALTRG
                     LRAVIAHHVIFHANRAGLLRDDQSALSHIAREVVMGTSDHTESPTEATADIDSVSAVNT
                     DTITTPTADAERLRNALVDQLRADGHARTPAVETALRTVPRHVFVPEASLEDAYANAPV
                     HIKYDTDGTSISCASQPGVVALMLDQLEAQPGERILELGAGTGYNAGLLAHLVGENGHV
                     TTLDVDDDLVEGARTHLAAAGITNVEAVTRDGALGYAEAAPYDRIIATVGAHGVPHAWL
                     QQLAPGGRLLVPQRLKGTVSRSIAYEQRDGRWVSLGSEMNTFMPLRRGIADDDRRVIPL
                     STDGAVRLQAPAGLNIDADALAGVLDQPRTEEWTGMTVRAMESPEWMELFVTCSLPSGL
                     IRMLFPQSAKGALLTEDPYPSSTAVIDKGAVTYLARRVSKEKTPEDDKLWEFGVIGHGP
                     GSDELAARVADAIRTWDRDYRDREATFEIQPLDAPEIEQRPGLFALDTPLNRIVVDWR"
     gene            16416..17534
                     /locus_tag="EHO50_RS16630"
     CDS             16416..17534
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010352619.1"
                     /locus_tag="EHO50_RS16630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128430931.1"
                     /transl_table=11
                     /translation="MDPHGPIAQRFPLVARFRPACLPLPQRVCAVVDLADTAVRATDQG
                     LASAVYNQAALIASDLDLPDLARAMCHQHAAAYLHACPLPGMSAIRGLEPVVNLARLQI
                     RAGHVDEGRQRLLDLYKAVESGTAARFEGVNVPADLTATDEDRQEVRAWLWRVLLADGT
                     RTLTTEGQWAEALAHIKAHHGIGKRMLDGRQVAVLAALVANDTAGAAGLLTDTLPGDPW
                     EQAVTACLTAFSRLSARQPVDRHLKDLLAAYLGRQAEPGMTVFDIRLGLTVLDAIGSAE
                     APAAHLVVEDLHRRTRNAEDGYAARENLAHPLFTAIATDRQSEDCRALVRACSLRAGTI
                     PEKWQGELKEALRACGSVIRESLGASSDCRTD"
     misc_feature    17163..17165
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17553..18518)
                     /locus_tag="EHO50_RS16635"
     CDS             complement(17553..18518)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535839.1"
                     /locus_tag="EHO50_RS16635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WYL domain-containing protein"
                     /protein_id="WP_128430932.1"
                     /transl_table=11
                     /translation="MTPDRFFSLMLLLASRDAVTTQELASALGVSLRTITRDLNWLRDA
                     GLPVTAQRGCLGGVTMLPGSGLDLTRLTPGERDHLSLTGLDEKQRAELNASVESRRALS
                     KIAAAQPRRVDELLPLTDVVHVDSRPWLQARASGTAPASLIGPVRRGRRLRIEYDSPRE
                     SCSRDLVVDPYGLFAKAGIWYLVADCARVPRMYRLERITTWKEVDQPRRIRESQTLATV
                     AAALVDQWEHNHAIEVSATIDQTQIERARRILGQRLVQEDQEESATGHRVRIRFLHLED
                     VRTLLPFGSTITVHGPTEARTHLRDLATNLAHHYAPSPTS"
     gene            18611..18976
                     /locus_tag="EHO50_RS16640"
     CDS             18611..18976
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134487.1"
                     /locus_tag="EHO50_RS16640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_128430933.1"
                     /transl_table=11
                     /translation="MTTSVVSIVYVNDAPAAARFYGDLLGMSPSFETPGYITFDLGPGA
                     DLAVWSGRFEDLSADVPRTSEVCLATDGGPDEVNAIFKQWQSKGDTILREPHDLGFGLT
                     FLAADPDGNRIRVAPRG"
     gene            complement(19178..20892)
                     /locus_tag="EHO50_RS16645"
                     /pseudo=""
     CDS             complement(19178..20892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002506.1"
                     /locus_tag="EHO50_RS16645"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIAAIKPAGSNTRGLLAYLYGPGKHDEHLDPHIVAGFAMLGMPDP
                     GRDENATLTELARYLDEPVSLRNSEFGKPVTDHVWHCPVRAAGEDRCLSDAEWAEIAQR
                     IVQAAGIAPAGDDLACRWIAVRHADDHIHILATTVREDGRRPKLHDSGLRVGDACREIE
                     KDYGLRRLKKGDRTGTRRPSQAEMHKAERLGWDQTSREWLQDRIRAAIPHVSNVEEFIA
                     YLQAEGVEVQARRGPSGDLLGYAAGRSGDVNEAGEQIFHPGGKIAPDLSLPKSRLASNP
                     AAPKNTPPPAAAAPAPPGSRPSRPSTPSTSTSPTKATPRRTSPPSAN"
     gene            complement(20889..21458)
                     /locus_tag="EHO50_RS16650"
     CDS             complement(20889..21458)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005476783.1"
                     /locus_tag="EHO50_RS16650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_128430934.1"
                     /transl_table=11
                     /translation="MAETAQRQGAPDQTFGAEGNPELDTLHTVQREILHPVRAAGAAEA
                     VGGEPVVKSVQPAIRRFTGTKRVVRVGPLRFTGDEHTQLQETAAEHGYKGDSGFAADIV
                     LAFITGRFTANLPLSEDRRRTHIFRAQVLRQLNRIGVNINQIARALNSDHTPPDIRQRL
                     TELHHLLELIAEALRQPADPETEASA"
     misc_feature    complement(21460..21479)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.56"
                     /tool="antismash"
     gene            complement(21619..22950)
                     /locus_tag="EHO50_RS16655"
     CDS             complement(21619..22950)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999217.1"
                     /locus_tag="EHO50_RS16655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_181449633.1"
                     /transl_table=11
                     /translation="MTSGSTVATSAATSQAASLAHWIPSPTAAVVPLVALALAAGWLWQ
                     RARNRGNGQQRGTAAIPVAAVAAIGCTAYSADTSWRFAADYLDMAGTVERAAMFAAAEL
                     ALFATALMARQNLNGPKQAPGAPGTLTWVITGVQIVPAYAESGLIGGTVRAFVGPVLAA
                     VLWHLAMGIELRNRSPHADSRSLTAVLTRQARERLLARLGIADRDADSARIIRERALDR
                     AVTLILRAETMKPEKRSKPRGRRLTRRLHKALEQADVDRDERQDELLLRKLATRQQALA
                     LVTVPLPARWPDLAERTTGGTVTARPRATSAKRAEAPGRPPAKVAGGDTADRAARPQPE
                     NRQQQPARTTSSPESKPGEEPPGDDPGKTSRAEPNGQGRKPRATRELLIDYADHLYDEH
                     GRLSRDLLEETVRANGYSVGSDIAGEVVRTVKNREQAARADHPH"
     gene            complement(23042..23740)
                     /locus_tag="EHO50_RS16660"
     CDS             complement(23042..23740)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004928356.1"
                     /locus_tag="EHO50_RS16660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_128430935.1"
                     /transl_table=11
                     /translation="MTATLSREPRQLGPLADRLNGILASRGIDPAAAAAQEPPAERVTA
                     LELADARIPARYRRALADHPQITAWADQIARAGRPGPSGPGIAEGPSLLIAGPTGTGKT
                     HQAYGAVRALLTRGVRLRWEATTSADLHARLRPRAGHDGERELQTLARCPLLLLDDLGA
                     AKTSEWTEELTYRLINHRYEHMLPTLITTNLPTAELRTALGDRVASRLAEMTERVILTG
                     PDRRRTAPAT"
     gene            complement(23737..24660)
                     /locus_tag="EHO50_RS16665"
     CDS             complement(23737..24660)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004928353.1"
                     /locus_tag="EHO50_RS16665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_128430936.1"
                     /transl_table=11
                     /translation="MARIRTIKPEAFVSESLAAVSLTAERTFIGLLTQADDQGRHRDHA
                     AIIAGQLWVLRPEHTPSDVETDLAQLADAGLLCRYKGPDDKRYLHIVTWSRHQKINRPS
                     KSRLPACPHHDVPAGARPSAAQVGFTEPSLPPREALREGSREMREPAVNPDTDDEVAGQ
                     AGYTEPSVRTHGGFPEPSVKPHCPDLGPRIMDLGDTPSGGASALAPDTVSAKQLLGEYV
                     AACNHRPPDAFLNQLGGQVRKLLDEGISPIHLRVALERHRVKGLSPSVLPSLVHEVMNA
                     ASPATPASHRAWTNPTDVVAAYGDEL"
     misc_feature    complement(24810..24830)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            25176..25418
                     /locus_tag="EHO50_RS16670"
     CDS             25176..25418
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178386.1"
                     /locus_tag="EHO50_RS16670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_128430937.1"
                     /transl_table=11
                     /translation="MAARPLEIGPYGIRAARTIEILRTERGLAQRELAAHVTALGRPMS
                     NTMLPRIERAQRRCDVDDLVALAQALDVPLLTLLQ"
     gene            25958..26164
                     /locus_tag="EHO50_RS16675"
     CDS             25958..26164
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009324638.1"
                     /locus_tag="EHO50_RS16675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_128430938.1"
                     /transl_table=11
                     /translation="MPARLLSIPAVAAALDVDRRTVYRFIAAGDLPVVDLRTGPGRSRV
                     RVPAAGLEEFISSRTVIPAMARR"
ORIGIN
        1 ctcctgccgg tatcctgctc ggtccatggt cctgattacg agggttaggg ccctgacacg
       61 gctggtcggc cgggtgatgc tcagggcgag gtcggcggct tgctggtgac atcccgcatg
      121 ggccagggcc gtggcgacgg ccgtcagcgc cttagccttc cgactggggt cgtcgattct
      181 tccggcgagt tcgatcgctt gctgggggtg cccaccatgg gcgatcacct cggccacggc
      241 cccgtacgcc cgctcccgca agtcggattc ggtgaccatt cgtgcgatgt cgatcgcacg
      301 ccgatggtgg ccggtgtgag ccatggccct ggcggcaagt gtgagggcca tcgcacgttg
      361 accggagtct ttggctaaga gggcgagctc ggccgccatg ctggcgagtt cggctgcctg
      421 cccgtgacac cctgtgagcg tcatggcctc ggcaacgacc gccagaatcg cagccttcgg
      481 cctgagggca gggtggccac gagcgagctt ggctgcctcg tgggcgactt cggctgcctg
      541 ctgaccgtca cccgcgcggg ccatttgtgc ggcgacagcc gccagggtgt cggcgcgccg
      601 gtagctgtcc gagatagcgc gggcgagttc ggcggccaga acgctctgcc ctccgcgggc
      661 aatggcccgg gcagcaaccg tgagtacccc gtcccgttcc tcatgattga cgatgctgcg
      721 agcgaggcga gcagcttcat cagcgagctc ggtggcctcc cggtggaatc cattgatggc
      781 caagctcttt gctatggcgc cgagagcctc ggcttgttcg gccggatcgg agatgccgcg
      841 ggcgcgttcg gcggctcgct cttcgtccgc cacgaaacgg gcgccctcgg cgggatcagt
      901 cgggactggt tcttcccagc cgcttgcatg agtgacgggg gcgttcttgc cggctgactc
      961 atcgccccca gcttcgcctg cagcggcgga cagcgagcgc agggccttcg ttcgttgctc
     1021 ggggtcgggg atgctttggg cgagctctgc ggcttgctcg cgacgccccg actctgccag
     1081 tgccctggcc gcagaggcga ggaccccggc ctgctgctcg gggtcggtga tgtcgcgggc
     1141 cagctcggcg gcctggtggg gacttccgct cgtggccatc gcatagacga cgactgcgag
     1201 ggcgtcgtca cgccggtccg gtctcgcgat gctgcgggcg aggtccgcgg cttgattcgg
     1261 atgtcctgcg tcgcagaggg cgttggcaac gtcccggagt tcccaggcgt cctggacggg
     1321 actcaggagc tgacgagcca ccgacgccac gagggacaca gtgttgcgat ctgctctccc
     1381 cccaaaaaga agccgtctga cgaggtcggg aatccgccgc gaaccatggg ccagctgggc
     1441 gagggctagg gcacgtcgaa catgccctag cctcgcccag gtctctatga cggtgtcggg
     1501 gataccggcg acatgcccgc ggatctcgtc gcggcggtga gccaggcgca cacacgccct
     1561 caggtcagga tcgccggcgg ctctgtgtag acggatggcg tcagcgatct cggccagagc
     1621 ctcggtgtcg gagcccgtgg tctcccacag tctctcgtgc cgcaccgcat cggtcgccaa
     1681 tgcggtgaga cgagtggtgt ccgacagact gcgtaatagc tgcgggtagc cgacgagggc
     1741 gtattccggc gtgtcgggtg gccagccaac gtcgcgccag acgtcggcga aggcgtgtac
     1801 ccgtgcacgg taaccctcaa gcgccgaccg ggatatccgc ttcagagcgc cctgttgcag
     1861 ctcttcgtgg gcgaaggaga acagacgcgc cggctgttcg ccgggtgccg gccattgggt
     1921 tggccggtgc tggaaggacc ggcccaatga cccgccaagg acctcttcga cttcccaagc
     1981 gctcacctcg cccatgaggt cggccaagtc ctgggggctc aaaccaccgt tggcggcggc
     2041 gatcaggcat gccacctcgc gcccgagtcc accacaagtc agcagggcgt gaaggtcgcg
     2101 ctctgcggct ctccgaagcg cctgggccgc ggatgacggt gccagcaggt ggttaatgcg
     2161 cgcgctgtgc agcgggtggt tctccagtac gtcgctgggg ataggcggat tcggacggcc
     2221 ggccacgata atccgcagtc ccggaggtgg cacgcgcggc agcagcgccg cgatgctgta
     2281 accgctgctg gccgactcga cgccggtgtc ctcgtcgagg ccgtcgacca gcagagccag
     2341 ctgtcggcct tcggccgtgg ctctgtcggc ggcgcgttcg agggcgtcca ggaactggcc
     2401 ttgtgaggca cagtccacgt cggtgtcgca caggtactcg cgcaactgcc cctgcagagt
     2461 ggccagaaag gcggtccggt ccgagcgccc ggcgttacgc gcggtgatga agaaggcaag
     2521 cacatccacg tttggtggag ggtgcagcgc gaactgcgcc ataagcgcgg tcttccccga
     2581 ccacgccggc gccagccatc gccagtaggc tgttcctgca tctccgccct ggacttcttg
     2641 gaaaccatcg ggtgcggtgg agaactcggc catggcctcc agttcggcgg cccggccctc
     2701 gaaccgggcg gctgctagct gggcgacctc atgcagatag ccagaacgca ggaccagggg
     2761 gcggcgctgc cccaagacca gatcaccggt gaccttcagg acgccgctat tcgcgagggc
     2821 accgtccacg gcatacgcct cacccgtgtc ctcggcccgc tcctgccgcc ttcccggcct
     2881 cactcgcaac gctcctttgc tgcgccttgt gagctcccat tgtgcactcc tgcaccgtct
     2941 ttgcaccgtg tcggtcggcg caccaagtac gtggcacgtg caccccacca attttgaaaa
     3001 cccgcgtcag gaagtagagg tgcttcgttc cagcgttcgg cgcacgcgca agtgtgtatc
     3061 ggtagcaagc ttatctcgta caactgacga gagttcattt ccccgactcg caacagcggc
     3121 gcggacttcg gcactaggat cctcagccaa tttggcaatc atctccgggg tgactggtcc
     3181 gtgtgccgcc ccacgcgctc tcacgatttc atcgttatgg aagaccagcc caatggcgta
     3241 ctccgcaaac tccctgatgc tagacgcgat ggcaacaacc gtgctggccc ccagcctttg
     3301 cacccttcga tcgccttcac gcagtagcgg cagcgccgag gccatagctt cttgagcgaa
     3361 gctttgttcc tcgggcgtca ttttagagtt gccttggcag gatgccgcaa acatctcaga
     3421 actggctacc agggccagta ccggcagttg gtcgccaccc atattcaact tgaatcgact
     3481 tagtgaatga tttgagtcga tttcaagttt gtctgtctgg gtgtagtgcg gagctctatg
     3541 cacttcaatc aagcgtaggg cgagatctct cgcggtagcc tttggcacct taggtacgag
     3601 atatcgcaac gctctcaccg tttctgcgcg gaatgcagct ccctgctgcg aatcctcggc
     3661 aatagccgtc atatgggagg ctacagctgc cgcgagattc gctggcggtc cagcagcaat
     3721 aagtgtggcg ttatctagcg tttcattctc tgagttcttc tccgtatcag tcggtggggg
     3781 agaatcagac gatgacaaag tttggtgcac tgctagtacg ccaccagcag gacgagcctt
     3841 ttttgaggtg agttcttcgg gagggaaatg agtaagattc tcagccgtaa gtagcacgag
     3901 tagcaggttc accgtagtcg actgctgtgt acccatagct gtcatacttc gcggaactcc
     3961 gacacgccgt cgcagtagtg ccgcgcaggc ccgacgtgcg gcgagttgaa caggctgcgt
     4021 tgcaacgccc caaccagcca agacttcgat tgccgactgt tgaccctctt cagcgagcgt
     4081 ggtgacaact ggcagcagcg gttcacgcgc ttctttcggg atgccttcta ccaaattcca
     4141 gagctctgga tgcggctgtg gaagttgcag catgcgcccg atcgcttttg cgacgtcctg
     4201 gcgacgagat tcgactgccc aataggtttg tacaagaaga ttcgcgatga catcgctgat
     4261 tcgagtgcta tttttcagcg caggctctgc catcgtaagt accctatcga cagctgtctc
     4321 agggatgcgc ataccgaatc gggcgatacc atccaacgca tcacgctctg gacgtacctg
     4381 gaatgcaggc gcttgccaca cgccctcggc aacttcaaga agtctctcaa ttacctctgg
     4441 cacgttgttg tccggaatgg tggaggattg cgcgccgatc acttgcactg cagcagcgcg
     4501 acgccgacgt agaggagagc caacccacat gctgacatct acagtgtccg gaattttctg
     4561 agcgaccttc ctagcttgag atgcctcacc ggcacggata tagcattcga gcgcatcggc
     4621 cggatgttcg ctcgcttcaa ggacctcgcc gaacagtttc agcgcaagga tttctccctg
     4681 taggtgcccg gccaatcggt gctcccacaa gtggcggcgg gtgctttcaa atgcatccgg
     4741 aagcctatta ccgcgtgcag cctgcatcgc ttcgagctct ggatcgtatg atgcagcaag
     4801 tagacgctgc cggttcggga gagaattggc aatgtgctgc agtccaggaa gctcgaaccg
     4861 gcccttatcc cattccagga ggcgtgacga ccacattgca cccagtgcat cgccgtagta
     4921 actttcttca ctgctggcga tcgctgcttg gcgccaatag ctgtcggctc gctcaaaatc
     4981 cccgtgagta gcgaaagcat aagcagcacg agaagctacc aggccacgaa catgaaggaa
     5041 tcgcccagcg agggcatcgt cgaccgctct gcgataggca gcgtcaacct cgtctggtga
     5101 cgctgccgca gtcaatgatg catcggcaac cgcacagcgc agtcgtgcgc ggatctctac
     5161 gtcagtgctg gtagcagccg aagccatctc gcgcaattca acgagtcgag tagccgtctg
     5221 ctcgtccgtt gtagcgacga ccgagcgtgc aggaacaaag tcgtataggc catcaaccac
     5281 tgcttgctcg agaagcagac acgacaatag tccggttcgt ggggcccgtg cggcagtcaa
     5341 cgtgcggagc gccgagacac cgtcatcgag gttgcttcct tcgccgtacc agaaggcgac
     5401 acaagtaagt gccgaaagtt ccgcccgttc tacgtcacta cgatgtggtg ccaagctctc
     5461 caaattactc agcaaagagc gcacggtact cgttgacccg gaaagtacac gctgcaatgc
     5521 caagtcgaac aataccctga acgcactttc gtgatcgccg ccagcttgcg cagcctgcgc
     5581 ctggcgtcga cgcatttctg ttgcgtgccc tgggaaattc ccttgaagca atccctctgc
     5641 aaccctccca aagagttggg aagccttaag tggatctatt ggttcagcct gagtggcatc
     5701 ggcttccaaa gcgtccaact gtagaacagc gattgggtct tcaacgagtc ccagtgattt
     5761 aggcgctgct aggtccgagg gcgatggttt gtagccacag tatgttttcg cccactgagg
     5821 cccgaaaact gcgtacacta gatgtggcat atcgcgcagc atgcgactta gagtttcagc
     5881 gccccatgcg tcgatctcta gatctccagc ataactggtc tgcaattctt caagggtgtc
     5941 gacattttcg gtatctctgt ccagtccagc cgatgtcacg actacaaacc gatatggaga
     6001 aaatctccgc gcctcacccc tgtattttgg cggccgaggc ggccctgaat actcttgaac
     6061 agcctcgcgc aacttggcgc cggtgagttc ctcaaaccgc tttacttgat aaagtaccct
     6121 tgccgatggg gtctctcgct cgacgatatc taggccgtac tgcttctggc ctcgtcggcc
     6181 ataaaactga accccgatat tgttccggcg actgacgatt tctgcgataa gcctttcgaa
     6241 gacttcagga tcgaggtcag cgagtggcaa tagggctgga ttttggacag gaaccggaag
     6301 ttccccggcc tgggtgcgcc ggagaacatc cggcaaagtc agctcaacga catcggttcc
     6361 aacctcaacg ttcgccacgg gataagaata cgaccgaact gtctcgctgc cgagcagttc
     6421 gtagtgcttc cttgtagcgc cttacaaccg gctcgtagct cgaaggcggc ggatcatcgt
     6481 gagtgctggt cagtcgacgc cgcggatcat gacgttgagg actggcgagg ccggtgacgg
     6541 ctggctctgg ccgatgtcct cgtaccccca cgacttatag agagcgtgga cttttccatc
     6601 gccggcggcc gggttgacca tgagcgtgac atacggctcg tcgcgggtgg cgaggagggc
     6661 gtcatggatg cggcgggcgg tgccagtctt ccgccaggtt ggccggacgc cgatctcctt
     6721 cagggccacc gccgggcgct cggtgtactt ctcggcgggc gccgggctgg tgcgctgcca
     6781 gtagcggtcg ccgtgctcga tggtgttgcc gtaggcgtag ccgaccggat gcccgtccgc
     6841 gtacgcgagg acggccgtga accccggctc ggcgccgtgc cggtccaggc gttcgccgaa
     6901 cgcggtgacc gcgtagttcg gcaggtggag gagtggggcg cgtacgtcgg cgtacacgtc
     6961 gaggaggtcg ccgcgggctg agtcgagggt gatgaaggtg cgcagttcga gggcgggcgc
     7021 cgtggtcatg cggccatcct ccaggtggcg gtgtgctcgg tccaggtctg cacggtggag
     7081 ctgccgggcg cggtggcgcg cagtgcggcc ccgaactcct gcagcatgcg cgtgacccgg
     7141 gcgtgctggg tcgcggcttc ggcggggacc ttcatcgcgg tggccgtggc tgcgtcgggg
     7201 gcgccctggg cgagctgggc gtgggcgagc cgggttgtgg tgatggcccg ggaacggatc
     7261 atgtggggcc ggagggcgga caggcagcgg tgggcgtggt actcggcggt cgagtagtcg
     7321 ccgagcgcca agtgcgcgga gagcgccagg gagtccagct cggcctgatc gtagaaggcg
     7381 agcatccaca ccggccggta gtcggtgggg tcggcgcgca gcatggcgtc ctgcgcctgc
     7441 tcgaaggccc ggcgggtgcc ggtgcggtcc tgtgccgtgc cgtggatggc gccctggcgg
     7501 gccagaccga gggaggcgaa cagggggtct cggcgggtga ggtgcaggtt gcgggcgacg
     7561 tcgttggcgg cgaacgcgtc ggcggggcgg cccatgtggc ggtacatggt gccagcgtgg
     7621 ctccagatgc ggaacttgat cgcctggtcg ccggacatct cggcgagggc ctgggcctcg
     7681 cgcatgtgcg ccatggcgat gtcgtagcgc cggccgtcga tggcggccca catcgcggag
     7741 gagcggaagg cggctgcgga ggcgtagagg ttgctgcgta cgcgctgggt ggcgctgccg
     7801 gcgttctgga ggttgagtgc ctcgtcggcg agggcggcgg cccgctgctc gatgccgagt
     7861 tgtccgccgt ggcggtgatc gctggcgatg atctcggcga agcgcttgtt gaggcgattg
     7921 acgtcgctca tgccgatacg gcgcggcgat gcggtgccgg gtgcggctgc tgcggcggca
     7981 gccgcagcga tgctgccgac gagagtacgg cgcttcatgt cagggtcctc ctgctgcagt
     8041 ggggccgggg tggacgaagg ccggccccgg ggcacgaacc ctaaagcgac ggcgggtaat
     8101 ccggtgacgt cctcaagtgc cctgcgggca gctgactttg gccacgtgac ccggcccgct
     8161 ttccatgccc tcaccgatga gccgtcgagc cctccagggc gcccggtcaa ccgttcaatg
     8221 gccctgttca cggcctcggc gaggctgttg gagctgtagc cgtgttcggt catccacgcc
     8281 tcaagaacgg tgttgcgggt ggtgtccatg cgggcacggt agcccgcgcg atcctcaccc
     8341 gccaggtaaa ggagaggtca aaacgcccta ggttggtccg tcgactgagc acctgaacgt
     8401 cctaaccctc ctgctgtgaa agggagttgt ctgggtgctg gtcgcccgcc gcgccccacc
     8461 gtgcgggcgg ctgttgacgg cccggctcgc ccctgaggtt cccccgcggg ggcgggccgg
     8521 gcgccgagac gacacgaagg ctccacccca atgacgagtc tgagaacacc agttgcggcc
     8581 ctctctgtcg gccacccgac gtacagccag accttcccgt gcaagccgtc cacggccgag
     8641 atcggccgcg gcctcgtccg agacgtcctc ggtgtgtggc acctcgacgg tctcgcccac
     8701 cgagccgcgc tgatcgtcac agagctgatc gcgaacgcct gccggcacac cccatgttcc
     8761 gagatccgcc tcacggttgc gcgaccggat gcgacacgac tgcgtgtcgg ggtcgtggac
     8821 cgggaaccag cgcgtctgcc catgctcagc caggcggctg acgacgacga gtcgggccgc
     8881 ggactgctcc tcgtcgatgc ggtcgccgac cgctggggct atgacctgca cggctcgggc
     8941 agacgcccct ggggcaaaga ggtctgggcg gaactccgca ccgggggcgg cgagtgagca
     9001 tcccggccac ggcaccctcg ccccttccgg atctcgctcg actccggccc cgccagcaga
     9061 tggccatcga ctgcgccctc tgcgcctggc cgctgggagc gagcggtcga cggctgggcg
     9121 agatacgcca ccggggccgg ccgttccagc tctgggcctg cgctcccaac tgccaggccg
     9181 ccagatcgac catcccgacc agctgagaaa ggggacgtcc ttccatggag tggccgtgga
     9241 tcaccggtga ttgctggctc ggctgcgggc gtaccggagt cctggtgatc tggctcggcc
     9301 cggtgcagtg ggacgggcag cacgcaccct tctacgcgtg cgagccctgc ctcgatcgtc
     9361 tcaaggccca ggcactcgcc tacttcatgg agcggcggcc ggcatccgct tgatcggact
     9421 cacggcacac gacttcccgg cgtgaggcag gcagcccgcg aggactttcc cacgcggagc
     9481 acgtcccttc gtgccgggcg gccaggagcc gtccggggag cagccgtctg gcgacgctct
     9541 cgtggcggca tctggtgggc gctccagccc agtaacacca caacgattgt gaggagttgc
     9601 agcatgacgc gcagcaccga tgttcccggc cgcaccgaag tacgcccgca gatcccgggg
     9661 gcgtcggacg gcttcgacct ggacgtctcc ctcgtcgaga tcgccgaccc ggcgggcttg
     9721 gtcaacctga ccgacgacaa ctgcgggtcc acctgcggcg cctgcaccac caacgtcgcc
     9781 tgacctggac ccccggtcac ctcggcctgg tgccgccgcg tctccgcgcg gcggcaccag
     9841 cccccggccc cctcacctac ggaggtactt ggtggttgct tcgcctgcag cgttccgtac
     9901 cggttccgct gctctcgtgc gcgccgtggc ccggccctcg ctgccgattc ctccatgccc
     9961 tgacctggat gaccgctcgc ccagtggttc gtctgcccgc gtggcgtggt tacgcgcggt
    10021 ctgggcgaac aaggacgtca ccgaggcact ccagcactcc agcccggtcc tggccgcgca
    10081 agtaggggcc ctgtgcacag ccgaggatcc cgccctccgg gatgtgcagc gcgccgcgct
    10141 gtccgtggcc cgctacctgc tccgggcgca gcaccgggcc acacccttcg gcctgttcgc
    10201 cggcgtggcc accgccgagt tcggcccaca ggcccgggcc gactggagcg aggagcacgt
    10261 ggccgtcggc cgcgcagggg cagagtggct ggcggccctg gtcgcacggc tggagtcatg
    10321 cccggacctc ctcgaacggc tacccgttgt cgtcaacaac accgtgacgt accggggaga
    10381 ccggctcgtc gtgccgttcc agcccgacgt ccaggacgac cggactcgcg cggtcgaggc
    10441 gtctctggcc ctgaccgaac cggtgcgcgc cgtccttgcc gcgggccgac taccgatccg
    10501 gttcggcacc ctcgtggaaa agctccaggc ggagttcccc caggccggtc ccgagaaggc
    10561 gcgtcaactg ctggcggagc tgatccggcg gcgggtactg atcacgggcc tgcacgctcc
    10621 gagcaccgag accgacgccc tcgggtatct ggtgggccaa ctcgacgcga tcggcgccgg
    10681 aatcctcgcc ccggtcgccg agaccgtacg cgaactccgc gcggtccggg cgggtctgga
    10741 ggagtgcgcc acgcacggcg gccgggacag cgtcgcggcg cggatgcgag acctcgtccc
    10801 tggcctgcgt caccaccccg tcgcgctcga cctccgtctg gacgcgcaga tcgttctgcc
    10861 ggaagcggtc gcccgagaga tcgagcgcgc cgctctcacc ctgacccgct tgagcatccg
    10921 cccgtacggg gccgccgcct ggaacgagta ccaccagcgg ttctacgagc ggtacggcat
    10981 cggcacgatg gtgccgctcg cggacgtcgt cgcggacagc ggcaccggct atcccgacgg
    11041 ctacccaggc gcttcggcca gcgcacgcag gccccgcgtc tccgctcggg atgacgccct
    11101 cgtacggctg gctcagaccg ccgcgctcga cggccgcgac gaagtgatcc tcacggacga
    11161 acagattgaa gccctggacg tgggtcccga caagcctcgg ttgccgccgc acttggagat
    11221 cggggtgcgg gtgcacgcgg ccagcctgga ggagttgcag cgcgggcagt tccggttgga
    11281 ggtcgtcagc gtgtcccgtg gcgccggcgt ctccacaggc cgattcctca gcgtgctggc
    11341 ccccgccgac cgggatgccc tggtcacaga gcttgccgac ctcccagccg cagacggcaa
    11401 caccatgccc gcgcagctct ctttcccacc cctcctcccc gagagcgccc acgtcacccg
    11461 ctccccacag gtgctaccca ccctgatcag ccttcaggag caccgcgccc cgcaggacac
    11521 cgtcctcacc ccggaggatt tggctgtggg gtgcgacggc cgccgcatgt acctcgccgt
    11581 ccccgagcga ggccaccgcg tcgaggccat cggaatgcac gcgctgaacc tccacaccca
    11641 caccccacca ctggtgcggt tcctcaccga actgtcccgc gcccagtgcg cgcaggtcac
    11701 cgtcttcgac tggggcgccg caacggcgat gcccttcctt ccacgtctgc ggtacggccg
    11761 gaccgtgctg gccccggcac gctggcggct ggaagcgtcc gaactgcccg gccatgcccg
    11821 tcctcgggct gagtgggacg ttgcgctcag cgactggcgt gcccggcgga ggctgccgcg
    11881 ccacgtccat ctcgtagaga acgaccggcg cctcttcctc gacctcgacg agggcggcca
    11941 ccgtgcgctc ctgcgcagac acctcgaccg tacgcgcctg gccgtactcg tcgaggcccc
    12001 ggaaccagag gcgtacggct ggtgcggcgg gcgagcccac gaggtcgtgg tgcccctcaa
    12061 agcaaccagg ccgtcgacat ggccgccact gccagccccc agccgggccc gtgccctgtc
    12121 tgcggaccag atgcagacgc ctgcctcttc ctcggttctt ctggccgccc tgtacggcga
    12181 tccccgccgc caagacgtct tgctctcccg gcacttgccc ggcctcctcg aacagctcgg
    12241 caacccgccg tggtggttca tccgcttccg agacccggac caacacctcc gcgtacgcat
    12301 cgccctcccc gacccggaag cctttgccgg cacggcccga acggtgagtg cctgggccga
    12361 cgagctacga agcatcggcc tgctgtccga tctgcgctat cccacctcct accgggagat
    12421 gggccgctgg ggctccggcg ccgcatggga ggcggctgag gaggtcttcc gggcggactc
    12481 gcgcgccgtc ctggcccagc tcactcagcc tcagcgccct ggaccgcgca cgctggtggt
    12541 ggcgcacacc gtcgctatcg cctccgcgtt cctcggcggc accgcagcag ggatgcggtg
    12601 gctgatcgac cacatccctc cgaaagcccc cgctcccgtt ccacgcccgc agttcatcga
    12661 cgccgtacgg ctcgccgacc cgtccgacga ctgggcggcg ctgcgccatg tcccgcgcgg
    12721 agacgccatc gtgtcgggat gggctgaccg ggatacggcg ctcgccaggt accggccgca
    12781 cctgcccggc ccggacaccc aaggcatctt cgtcgacgac gtcctgacct ccctgctgca
    12841 cgtccacttc gtgcgccacg tcgcagtgaa cttcccggag gaagaggtgt gcctctacct
    12901 ggcgcgcgcc gccgccctgg cctggaccgc ccgcacccgt gggaggacct cgtgaccgct
    12961 caccccacgc tcggcctggt ccacgccatc gccacccggc tcgccgaccc cgacaccgtg
    13021 cccctcggct ccagactgct gtcctcggac cggcagcatc ttgcttacgg cccgcccgga
    13081 atcgcgctcc tgcacatcga gctggccgcc aacggccgag gcccgtggca ccgcgcccac
    13141 gactggctca ccgccgcctc ccggcaaccg ctcaccagcg gcccggacag ccacccgttc
    13201 tacggagtgc ctgccttcgc ccatgccctg agctgtgccg ccgaccacct tcctggctcc
    13261 taccagcgcg ccctcgacgc gatggacgga cagatcgcag tcgacgtcgg acgccgtctc
    13321 gacgccgcac accgccgcat cgacgccgga cgcctgccgc agctcgtcga gttcgacgcc
    13381 atccggggcc tcaccggata cggcgcctac ctactgcgcc aagaccccgg cagctccacg
    13441 atgcgcgccg ttctcgacta ctgcgtgcgc ctcaccgaac cgatcaccca ccacggcgag
    13501 accatgccgg gttggtggac ggagaccggg ccctcgggca gccccgacga ccgattccct
    13561 ggagggcacg ccaacaccgg tatggcacac ggcatcggcg gcgtgctcgc gctcctggcc
    13621 ctcgccgctc ggaacggctt cctcaccgac gggcaccacg cagcactgcg caccatcctg
    13681 gcctggctgg accgctggaa agagagggcc gacggcggac gggcctggcc gtactgggtc
    13741 actcagggcg aactgcgccg ggggcgtctc ggctcgtcag gccccaggcg gccgtcctgg
    13801 tgctacggca ccgccggcct tgcccgcgcc cagcaacttg ccgccctcgc cctcggcgac
    13861 accgaccgcc agagcgacgc ggagaaagcg ctcgtggccg ccctcaccga tcccgagcag
    13921 ctgaaggcca cgacggacaa cggcctctgc cacgggttct ccggcctcgc ccacgcagcc
    13981 gcgcgtacgg ccgacgacgc ccacccctcg accgcagaga aactccgcgc cgcgattccg
    14041 gccctcctgg ctgcggtcac ccctccgggc accgaccccc aactcatggc cacggcgctc
    14101 atccaggacg agaaaggcgg ccccggtcta ctcgacggcg ccgccggcat agccctggcc
    14161 ctcctcgcgc ccagcatcac cgcaccaccc cggtccgcct gggacgcatg cctcctcatc
    14221 gcttgatcca ccaaccgaag gacatccatg ccccccgacc gctggcagca gcacaacatc
    14281 accttcgtcc agcgcgagag cgcccggcgc accatcgcag aacgcctcgg cccagccctt
    14341 atcgaggcag aggccgacgg gcagctcacc agctggtggt tcatgaacaa gcagccctgg
    14401 ccgctgcgtt acctcgccga cgagccctca ccagccattg agtcgctcct gagcgacctc
    14461 atcggcgacg gcgtggccgt ctcgtgcttg ccctgcgtct acgagcccga gaccgacgca
    14521 ttcggcggac ccgaggccat ggacgcagcc cacgaactgt tccacagcga ctcccgccac
    14581 ctgctcacct accagccgag cccgatgcac ttgggacgcc gggagaccgc cgtcctgctg
    14641 gcgagcgtca tgatgcgcgg tgctggactc gactggttcg aacagggcga cgtatgggcg
    14701 aaggtggcag ctcttcgacc ggccaccaat ccaccacaac cggaacgagc cgccgaactg
    14761 gctccggcta tgcggaagct catgaccgcc gacacccaca gcctctgccg cctgggtcac
    14821 ccactccacg cgcacgagga atgggtgacc gccttcgaac aggccggcgc cacgctcgcc
    14881 gaactcgcag gccgcggcgc cctcacccgc ggcctgcgag ccgtcatcgc ccaccacgtg
    14941 atcttccacg ccaaccgcgc cggtctcctc cgggacgacc agagcgccct gtcccacatc
    15001 gcacgagagg tagtcatggg aacgagtgac cacaccgagt cgcccaccga ggcaacggcc
    15061 gacatcgata gcgtcagcgc ggtgaacacc gacacgatca ccacccccac ggcggacgcc
    15121 gagcgcctcc gcaacgccct tgtcgaccag ctccgtgcgg acggacacgc ccgcacgccc
    15181 gccgtcgaga ccgcgttgcg gaccgtgccc cgccacgtgt tcgtgcccga ggcatccctc
    15241 gaagacgcct acgccaacgc accggtgcac atcaagtacg acaccgacgg aacgtccatc
    15301 tcctgcgcct cccagccagg cgtcgtcgcc ctcatgttgg accagctcga agcccagccc
    15361 ggcgagcgca ttctcgaact cggtgccggc accggctaca acgccggtct gctcgcccac
    15421 ctggtcggtg agaacggaca tgtgaccacc ctcgacgttg acgacgacct cgtggagggt
    15481 gcccgcacgc acctcgccgc cgccgggatc accaacgtcg aggccgtgac ccgcgacggg
    15541 gccctcggct acgccgaagc agcgccgtac gaccggatca tcgccaccgt cggcgcgcac
    15601 ggtgtaccgc acgcctggct gcagcagctc gcacccggcg gccggctcct cgtcccccag
    15661 cgtctcaagg gcaccgtctc ccgctccatc gcctacgagc agcgcgacgg ccggtgggta
    15721 tccctcggta gcgagatgaa caccttcatg ccgcttcggc ggggcatcgc tgacgacgac
    15781 cgccgagtga tccctctcag cacggacggc gccgtacgac tccaggcccc cgccgggctc
    15841 aacatcgacg ccgacgccct cgcgggcgta cttgaccagc cgcgcaccga ggagtggacc
    15901 ggtatgacgg tccgcgccat ggagtcgcca gagtggatgg aactgttcgt cacctgctcc
    15961 ctgccctccg gcctgatccg gatgctcttc ccccagagcg ccaagggcgc tctgctcacc
    16021 gaggacccct acccctcgtc aactgcggtc atcgacaagg gcgccgtcac ctacctcgcc
    16081 cggcgcgtat ccaaggagaa gacccccgag gacgacaagc tctgggagtt cggcgtcatt
    16141 ggccacggcc ccggcagcga tgagctggcc gcgagggtcg ccgacgccat ccgcacctgg
    16201 gaccgcgact accgcgaccg tgaggccacg ttcgaaatcc agcccctcga cgccccggag
    16261 atcgagcagc gccccggcct cttcgccctc gacaccccgc tgaaccgcat cgtcgtcgac
    16321 tggcggtgac accccacgtg gggcggcggt gcccgcggca cgcaggcggc gggcaccgcc
    16381 gccccaccag ccctcactca cacactgggg gacccatgga cccgcacggc cccatagccc
    16441 agcgcttccc gctcgtcgcg cgattccgac ccgcctgcct acccctgcct caacgcgtat
    16501 gtgctgtcgt cgacttggcc gacaccgcgg tgagggcgac cgaccagggg ctcgcatcgg
    16561 ctgtctacaa ccaggccgcg ctcatcgcct ccgacctcga cctccccgac ctcgcacgcg
    16621 cgatgtgcca ccagcacgcc gccgcctacc tccacgcctg tcccctgccc ggcatgagcg
    16681 cgatccgcgg actggaacca gtcgtcaacc tggcccgcct ccagatccgc gccggccacg
    16741 tcgatgaggg ccgtcagcga ctcctcgacc tgtacaaggc cgtcgagtcg ggcacggccg
    16801 cccgcttcga gggcgtcaac gtacccgcgg atctcactgc gaccgacgaa gaccgccagg
    16861 aggttcgcgc gtggctgtgg cgcgtcctcc tcgccgacgg cacgcgcacc ctcactaccg
    16921 aggggcaatg ggccgaggcc ctggcgcaca tcaaagccca ccatggcatc gggaagcgga
    16981 tgctcgacgg gcggcaggtc gccgtactcg ccgccctcgt tgcgaacgac acggcagggg
    17041 ccgctggcct gctcaccgac acgttgcccg gcgatccatg ggagcaagct gtcacggcct
    17101 gtctgaccgc cttctcccgg ctcagcgcca ggcagcccgt cgacagacac ctgaaggacc
    17161 tgttagccgc ctatctcggg cggcaggccg aacccgggat gaccgtcttc gacatccggc
    17221 tcggccttac ggtcctcgac gcgatcggct ccgccgaggc gcccgccgca cacctggtgg
    17281 tcgaggacct ccaccgcagg acaaggaacg ccgaggacgg ctacgcagcc cgcgagaacc
    17341 tggcgcaccc cctgttcacc gcgatcgcca cagaccggca gtcagaggac tgccgtgcac
    17401 tggttcgtgc ctgctccctc agagctggga ccatcccgga aaagtggcaa ggagagctga
    17461 aggaggctct gcgtgcctgt ggcagcgtga tccgggaaag cctcggcgcg tcgagcgact
    17521 gccggactga ctgaacacct agatgttgcg ggtcaggacg ttggtgacgg cgcatagtgg
    17581 tgggcaaggt tggtggcgag gtcacggagg tgagtcctgg cttcggtggg gccgtgcaca
    17641 gtgatggtgc tcccgaacgg cagtagtgtt cgcacgtcct ccaggtgcag gaagcggatc
    17701 ctcaccctgt ggccggtggc ggattcctct tgatcctcct ggacgagtcg ttggccgagg
    17761 atccgtcgcg ctcgctcgat ctgggtttgg tcgatggtgg cgctgacctc tatcgcatgg
    17821 ttgtgttccc actggtcaac gagcgctgca gcgacggtgg ccagggtctg gctctcgcgg
    17881 atccgtcgtg gctggtcgac ttctttccac gtcgtgatcc gttcgagtcg gtacatccgt
    17941 ggcactcggg cacagtcggc gacgaggtac cagatgccgg ccttggcgaa cagcccgtag
    18001 ggatccacga ccaggtcgcg tgagcatgac tcgcgggggc tgtcgtactc gatccgtagc
    18061 cggcgaccgc gccgcaccgg gccgatcagc gaagccggag ccgtgccgga agcacgggcc
    18121 tggagccagg gacggctgtc cacgtgcact acgtcggtga gcggcaggag ctcatcaacc
    18181 cgacgtggct gtgcagcggc gatcttggag agcgcgcgcc ggctctcgac cgatgcgttg
    18241 agctccgcac gctgcttctc atccagccca gtgagcgaca gatgatcacg ctcacccggc
    18301 gtgagtcgcg tgaggtcaag tccggacccg ggcagcatgg tcacgcctcc gaggcagccc
    18361 cgttgcgcgg tcaccggcag accggcgtcg cggagccagt tcaggtcccg ggtgatggtt
    18421 cgaagggaca ccccgagcgc cgaggcaagt tcctgtgtgg tcacggcatc cctcgatgcc
    18481 aggagcagca tcagggagaa gaagcggtct ggggtcacac accaagcttt tcaggaattg
    18541 cgacatgatg cggcgcatat cccggtcagg ctggcggatg cgtacccacg acctgcgaga
    18601 aggaagaacc atgaccacat ccgtcgtgtc catcgtctac gtgaacgacg ctcccgccgc
    18661 agcgcgtttc tacggcgacc tcctcggcat gagcccgtcg ttcgagacgc cgggatacat
    18721 caccttcgac ctcgggccag gcgctgacct cgctgtgtgg tccggccggt tcgaggatct
    18781 gtcagcggac gtcccgcgca ccagtgaggt gtgcctggcc accgacggtg ggcccgacga
    18841 ggtcaacgcg atcttcaagc agtggcagtc caagggtgac acgatcctgc gcgagcctca
    18901 tgatctgggg ttcgggctca ccttcctcgc agccgatcct gacgggaacc gtattcgcgt
    18961 ggcaccgcgg ggctgaaagg ccacagtgag gcaggcgcac acgatgggtg tcgcgcctgc
    19021 cgtcgtctga cttcgcaagg acgacgtgtg cccccgcgaa tgcgcccctg agcgtcgagg
    19081 gtcgtaggca gctcgtgaag cacgatcacc agatccagcg cgatgcatgc ttgccactct
    19141 ggcagtcgcg cagagacgcg gcaggagtac tcggcagcta ccggcgcggc cgacgctgct
    19201 gttcggcaag cgtcgtgttc gccgctgcag gctgatcgtt tcgggtcggc tgggcaggga
    19261 tcgagcctgc catggtcgac tgtaggcgtg cggcctcggc aaggcggttg cgtgccgggt
    19321 ttcggccggt gtgttggatg cgggtgatca gcacgcgcgc gggctggcgg gcggtggtca
    19381 actcgcgtcg ggcggcagct tccttgagga gctggtgagg ctggtggcca cgggcttcgg
    19441 cgtcggcgag gacggtggcg agtgccggcc aggccgggtc ggtgaggatc cgctcggcgt
    19501 ggtcggggag ggctgctcgt acgtcgttgg cgagaacacg gcgggcttga tccctgggcg
    19561 gccgggctgt gagttcggcg agcgtcggag caagtgctcg gtctgcggcc gcctgcaggt
    19621 gctggacggc ttgacgggcg gcgtcggcct ggtgggcgtg gctcttcgct tcgtgccagc
    19681 gcccggccac gacggtcgcc cagacgaggg cggcgaccag ggcggccagt gcgctcccgt
    19741 cggggccggt ggcggtgtgg acgatgtcgc gggccgcgct gcgcagcgcg tgagcggcac
    19801 ggtcttcggc ccgtacctgg gaccgttggg ctcgggcgaa cgccttggcg gcggcctgga
    19861 gttcggcgcg caggtgatcc ggggccttct gagcagtggc ttcagtcagt tcgccgaggg
    19921 cggtgacgtg cgcctgggcg tggctttcgt cggcgaggtc gatgtggagg gtgtcgaggg
    19981 cctcgatggc ctgctgccag ggggtgctgg ggcggctgcg gcgggcggtg gggtgttctt
    20041 cggggcggct ggattcgagg cgagccttga tttgggcagg gagaggtcgg gggcgatctt
    20101 gcctccggga tggaagatct gctcgccggc ctcgttgacg tcgcccgagc ggccggcggc
    20161 gtagccgagg agatctcctg atgggccgcg tcgggcctgg acctcgacgc cctcagcttg
    20221 caggtaggcg atgaattcct ccacgttgct cacgtgcggg atggcagcgc ggatgcggtc
    20281 ctggagccac tcgcggctgg tctggtccca gccgaggcgt tcggccttgt gcatctcggc
    20341 ctggctgggg cggcgagtac cggtgcggtc gcccttcttc aggcggcgca gcccgtagtc
    20401 cttctcgatc tcgcggcagg cgtcgccgac gcgcaggccg ctgtcgtgga gtttggggcg
    20461 acggccgtct tcacggacgg tggtggcgag gatgtggatg tggtcatccg cgtggcgtac
    20521 ggcgatccag cggcatgcca ggtcgtcacc ggccggagcg atgccagcgg cttggacgat
    20581 gcgttgggcg atctcggccc actcggcgtc ggagaggcag cggtcctcgc cggcagcgcg
    20641 gacggggcag tgccagacat ggtcggtgac cggcttgccg aactcgctgt tgcgcaagga
    20701 gaccggctcg tcgaggtagc gggcgagttc ggtgagggtg gcgttctcgt cgcggccggg
    20761 gtcgggcatg ccgagcatcg cgaagccggc cacgatatgc gggtcgaggt gctcgtcgtg
    20821 cttgccggga ccgtagaggt aggcgagcag gccgcgggtg ttggacccgg ccggtttgat
    20881 ggcggcgatc acgcggacgc ctccgtctcc ggatcggcgg gctgacgcag ggcttcggcg
    20941 atcagctcca gcaggtggtg gagttcggtg aggcgttggc gtatgtcggg tggggtgtgg
    21001 tcgctgttga gggcgcgggc gatctggttg atgttgacgc cgatccggtt gagctggcgc
    21061 aggacctggg cgcggaagat gtgggtgcgg cggcggtcct cggacagggg caggttggcg
    21121 gtgaaccggc cggtgatgaa ggcgaggacg atgtcggcgg cgaagccgga gtcgcccttg
    21181 tagccgtgct cggcggcggt ctcctggagt tgggtgtgct cgtcgccggt gaagcgcaag
    21241 gggccgacgc ggacgacgcg tttggtgccg gtgaagcggc ggatcgccgg ctggacgctc
    21301 ttcacgacag gctcaccgcc gaccgcctca gcagctccgg cggcgcgtac ggggtgcagg
    21361 atctcgcgct gaacggtgtg gagcgtgtcc agttcggggt tgccctcggc cccgaacgtc
    21421 tggtccggcg ccccctggcg ctgggccgtc tccgccaccc ccggggcgga gctccccgaa
    21481 gtccggcctt gagtcggact cggggtacta ctggctcccg ccgaggtggg ggtggtcatc
    21541 tctgttggag cgaccggcag ttcgtggtgc gagtcgtgca ttgatcggtc ttccatgagg
    21601 ttgggggcgg gggcggtctc agtgagggtg gtcggcgcgc gcggcctgtt ccctgttctt
    21661 gacggtgcgg acgacttctc cggcgatgtc gctgccgacg ctgtagccgt tcgcgcgcac
    21721 ggtctcctcc agcaggtcac gggagagacg tccgtgctcg tcgtagaggt gatctgcgta
    21781 gtcgatgagg agctcgcgtg tggcgcgcgg tttgcggccc tggccattcg gctctgcccg
    21841 cgaggtcttg cccggatcgt cgcccggcgg ttcctcgccc ggtttcgatt ccgggctgga
    21901 ggtcgtgcgg gcgggctgct gctggcggtt ctcgggctga gggcgggctg cccggtcggc
    21961 agtgtcaccg cccgcgacct tggcgggcgg gcggcccgga gcctctgccc gcttcgctga
    22021 cgtggcccgc gggcgggcgg tcacggtgcc gcccgtcgtg cgctcggcaa gatcgggcca
    22081 acgggcgggc aacgggacgg tgaccagggc gagggcctgt tggcgggtgg cgagcttgcg
    22141 cagcagcagc tcgtcctggc gttcgtcgcg gtcgacgtcg gcctgctcca gggccttgtg
    22201 caggcggcgg gtgaggcgtc ggcctcgcgg tttgctgcgt ttctcgggct tcatggtttc
    22261 tgcccggagg atcagggtga ccgcccggtc gagggcgcgc tcgcggatga tccgggcgga
    22321 gtctgcgtcc cggtcggcga tccccaggcg ggccagcagc cgttcgcgtg cctgtcgggt
    22381 gaggacggcg gtcaggctgc gggagtcggc gtgcgggctg cggttgcgta gttcgatgcc
    22441 catggccagg tgccacagca cggccgccag caccgggccg acgaaggcgc gcacggttcc
    22501 gccgatcagt ccggactcgg cgtaagcggg cacgatctgc acgccggtga tcacccaggt
    22561 gagggtgccg ggcgctccgg gtgcctgctt ggggccgttg aggttctgcc gggccatcag
    22621 ggcggtggcg aacagggcga gttcggcggc ggcgaacatc gcggcgcgct cgacggtgcc
    22681 ggccatgtcg aggtagtcgg cggcgaaccg ccagctggtg tccgcgctgt atgcggtgca
    22741 gccgatcgca gcgacggcgg cgaccgggat ggcggcggtg ccacgttgct gcccgttgcc
    22801 gcggttgcgg gcgcgctgcc acagccatcc agcggccaag gcgagggcaa cgagtgggac
    22861 tacggctgct gtgggtgagg ggatccagtg cgccagggac gctgcctggg acgttgcggc
    22921 gcttgtggcc acggtgctgc cggatgtcat gcaggggctc tccaagggct cgcgcgatcg
    22981 agggcatgcc tgtgggcggg cgggtgaggt gaaggttggg gggggagacg cgcggctgcc
    23041 gtcaggtggc gggcgcggtg cggcgtcggt cggggccggt gaggatgacg cgttcggtca
    23101 tctcggcgag gcgggaggcg acgcggtcgc cgagtgcggt gcgtagctcg gcggtgggga
    23161 ggttggtggt gatgagggtg gggagcatgt gctcgtaccg gtggttgatg agccggtagg
    23221 tgagctcctc ggtccactcg ctggtcttgg ccgcgccgag gtcgtccagg agcagcagcg
    23281 ggcaacgggc cagcgtctgc agttcccgtt ctccgtcgtg gccggcgcgg gggcggagcc
    23341 gcgcgtggag gtcggcggag gtggtggcct cccagcgcag gcggacacct cgggtgagga
    23401 gggcgcgtac ggcgccgtac gcctggtggg ttttgccggt gccggtgggg ccggcgatca
    23461 gcagcgacgg tccctcggcg ataccgggtc cgctcgggcc ggggcgtccg gcgcgggcga
    23521 tctggtcggc ccaggcagtg atctgggggt ggtcggccag ggcgcggcgg tagcgggcgg
    23581 ggatgcgcgc gtcggccagc tccagggcgg tgacgcgctc ggcaggtggt tcctgggcgg
    23641 cagcggcggc ggggtcgatg ccgcggctgg ccaggatgcc gttgagccgg tcggcgagtg
    23701 gaccgagctg gcggggctct cggctgaggg tggcggtcag agctcatctc cgtaggcggc
    23761 gacgacgtcg gtggggttcg tccacgcccg gtgggaggcg ggcgtggcgg gggaggcggc
    23821 gttcatgacc tcgtggacga ggctgggcag aacgctcggg gacaggccct tgacgcgatg
    23881 ccgttcgagg gcgacccgga gatggatggg ggagatcccc tcgtcgagca gcttgcgcac
    23941 ctgtccgccg agctggttca ggaaggcatc cggcgggcgg tggttgcacg ccgcgacgta
    24001 ctcgccgagg agctgcttgg ccgagacggt gtcgggcgcg agggcgcttg cgccccccga
    24061 aggggtatct cctagatcca tgatcctagg tcctagatcc gggcagtgag gcttcaccga
    24121 cggctccggg aatcctccgt gagtcctcac tgagggctcc gtgtatccgg cctgacctgc
    24181 gacttcgtca tcggtgtccg gattcactgc gggctcgcgc atctcccgtg agccctcacg
    24241 gagggcttcg cgaggcggca gtgagggctc cgtgaagccg acctgtgcgg cgctcggcct
    24301 ggctccggcg ggaacgtcgt ggtgcgggca ggccgggagg cggctcttgc tcggccggtt
    24361 gatcttctgg tgccggctcc aggtgacgat gtgcaggtac cgcttgtcgt ccggcccctt
    24421 gtagcggcag agcagcccgg cgtcggcgag ctgggcgagg tccgtctcga catcggacgg
    24481 ggtgtgctcc gggcgcagca cccacaactg gcccgcgatg atcgcggcgt ggtcgcggtg
    24541 gcggccctgg tcgtcggcct gggtgagcag gccgatgaag gtgcgctccg cagtcaggga
    24601 gacggcggcc aaggactcgg agacgaaggc ttcgggcttg atggtgcgga ttcgggccaa
    24661 gaggggggtg gttcctcact cggttgcaga tgggcgggca cccattgctc accgtcgatg
    24721 ggcggtacgg gcttcagggg tgggggagtt gactggttct gccgcgcggg gcgcgtcgat
    24781 ggccactcgc gctttccggg ggtgtcgtca acatagccac acccatgcgg cgcaagtcca
    24841 gccctgtccc gcgcaatctc tcacggcaga aaggcgcaga gaaaggagtc gggaagggga
    24901 ggttgcaaaa ctgtagggca cgatcggcgg ttgacgaaat agttgccttg gttgccgagc
    24961 cagaagcatc acatagagaa gccgttgacg ccccgccgag agggaagcta caacacaaca
    25021 ccccacgtca gagcactcgc agagtggcag tagatgtacc ggatttcgat acatcccgac
    25081 cttccgcggt cgcttaccca gccaaccgcg cgagcgcaac atagacgacg atcgccggtt
    25141 caccaaaccg gcgaatgcga gctacaaatg gagccatggc agcacgaccc ctggaaatcg
    25201 gtccgtacgg aatacgggcc gcccgcacca tcgaaatcct ccgcacggaa cgcggcctcg
    25261 ctcaacgcga actcgccgcc catgtcaccg ccctcggccg cccgatgtcc aacacgatgc
    25321 tgccccgcat cgaacgcgcc caacgccggt gcgacgtcga cgacctagtc gctctcgccc
    25381 aagccctgga tgtccctctc ctcaccctgc tccagtgatc ggctcgtgag gcgagaagca
    25441 gccgactcct gcgtgtccgg ccccctgccc tgtcggctcg tgagctgagt ctgccggggg
    25501 cttatagcac ccgatccccg gttaccgaaa ccggggattc tccggatggt ttgaggtgtc
    25561 caacgggacc gacccctctg tcccacgtgg ctagacgcgc cccaacccaa ccaagggggt
    25621 acacgaagtg cctgcgcttt ccccgcgctg ccgtaccgaa gagccggctg tcgcagagtt
    25681 ccgcccccac tccagcgtcc tccgaccgac cgtttcggct cttcctcacg ccttcaaggc
    25741 gtgagctcag cccgaggccc cgcctgacaa cggcgcggtt gccaaacgcc tgccccgcac
    25801 atcgccagcc ctcgtgccca cgacgcgtca cgccgtaacc gctgacgcct cgatgccctg
    25861 gcaaggctga ttggccttct gctgaaccgg cctacagccc ggctgccgaa tcgccgggcc
    25921 actcatccca ccccgcctgc accgccaagg actccccatg cctgcccgct tgctctccat
    25981 acccgctgtc gccgccgctc tggacgtcga ccgccgcacc gtctaccgct tcatcgccgc
    26041 cggcgacttg cccgtcgtcg atctccgtac cgggcccgga cgttcccgcg tgcgtgtacc
    26101 cgctgccggt ctggaggagt tcatcagcag caggaccgtc atcccggcca tggcccgtcg
    26161 ctgacccaca ccagtttccg aatccctcgg cagtcgaaca aggagtagat ccacgtacct
    26221 ccggaaactg gcatccggca agtggcaggc gaccgtacgc aacagagcgg gagaccggtt
    26281 cagcgagtcg ttccccctca aagcacaggc ccgagcctgg ggcgccgac
//
