LOCUS       NZ_CP025227            21901 bp    DNA     circular CON 14-APR-2024
DEFINITION  Actinomyces wuliandei strain 299 chromosome, complete genome.
ACCESSION   NZ_CP025227
VERSION     NZ_CP025227.1
KEYWORDS    RefSeq.
SOURCE      Actinomyces wuliandei
  ORGANISM  Actinomyces wuliandei
            Bacteria; Actinomycetota; Actinomycetes; Actinomycetales;
            Actinomycetaceae; Actinomyces.
REFERENCE   1  (bases 1 to 3107761)
  AUTHORS   Zhu,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2017) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, No.155 ChangBai Road, Changping District, beijing
            102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_004010955.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 19:14:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,606
            CDSs (total)                      :: 2,544
            Genes (coding)                    :: 2,496
            CDSs (with protein)               :: 2,496
            Genes (RNA)                       :: 62
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 50
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 18 of 48
            Pseudo Genes (incomplete)         :: 37 of 48
            Pseudo Genes (internal stop)      :: 3 of 48
            Pseudo Genes (multiple problems)  :: 9 of 48
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:15:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2689665
            Orig. end                         :: 2711566
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP025227.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21901
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphoglycolipid"
                     /region_number="11"
                     /rules="(MoeO5 or moeGT)"
                     /tool="antismash"
     cand_cluster    1..21901
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(MoeO5 or moeGT)"
                     /kind="single"
                     /product="phosphoglycolipid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21901
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11901](-)"
                     /cutoff="20000"
                     /detection_rule="(MoeO5 or moeGT)"
                     /neighbourhood="10000"
                     /product="phosphoglycolipid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11901)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(MoeO5 or moeGT)"
                     /neighbourhood="10000"
                     /product="phosphoglycolipid"
                     /protocluster_number="1"
     misc_feature    8..19
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(339..353)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            580..1311
                     /locus_tag="CWS50_RS11115"
     CDS             580..1311
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CWS50_RS11115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127842842.1"
                     /transl_table=11
                     /translation="MRVLRTTEMTLRDLFGRGWVLVLLMLLPLVFYAARRSDAGWQALR
                     MGCMGLAWAVGTVSLFAQQTVRDLDPRLRLAGVRAWEIFVGRLLALLGVALVVGSLYAV
                     GLVLDQDVLHGWSVVAALLLSAALPVPVGMVVGLLIPRELEGMLVLIMVVGLQTIVDPG
                     RSLAEILPLWSTRNLLNYGVDGVGSLEDSWLHAAVYGGACLLVGFVVSAVRLRRRRHLV
                     LLPRAQALPGSGARTAGPSSG"
     gene            1389..3227
                     /gene="asnB"
                     /locus_tag="CWS50_RS11120"
     CDS             1389..3227
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01536.1"
                     /locus_tag="CWS50_RS11120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_127842843.1"
                     /sec_met_domain="GATase_7 (E-value: 3.7e-35, bitscore:
                     117.8, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-69, bitscore:
                     232.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGVVGDPDARQGLVAMLARLVHRGPDGEGRWHEGGTALGHR
                     PPVVGDLGTGGVQPVVSADGSLVLVFDGQLCNRRDLRRQFEGRGHRFTTRCDGEIVVAA
                     LQEHGVDALRRFEGVFTLAWWDRRAGSLWMARDRVGEKPLYYLEDRGRFAFASEIGALT
                     ALGWDDGGIDPEAVALLLSRRCVPSPWTIHRRIRQLPPGSVLELSRGRTRIAPYWSAIE
                     AVTTGQERTRISDHWEVERALRRAVSRQLEADVPLGVLLSGGTDSSLVAALAGEQHDAP
                     VTAFTLSWQDRDLDEASAAGATANALGMDHVVVPLKDPELVDTVLAVQRVFGEPFADPG
                     AVPLMVLSACAAQHVTACLTGDGGDECFGGYRRYSRLSRLGRPASRAHALRPLVERLPR
                     GLRSSRLRFLGRSLAEIYTLVSASWDPLVSGELAGLSVPPYPPTAAFDVSDLSVRRMAM
                     LTDFMGYLPDQLLAKTDRTCMANSLEARAPLLDPCVVNLSFALDDRLIVGKRVLRDIVA
                     CRLPHLSRQAVKRGFETPTERWLRGPLRSLVSETIRKESLEARGIARPEIALDMVARQR
                     AGEPLSRIVWPLLMLTLWEPGGGPRPSAAGLSRHAQ"
     misc_feature    2589..2591
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3208..3696)
                     /locus_tag="CWS50_RS13875"
     CDS             complement(3208..3696)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /locus_tag="CWS50_RS13875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine acetyltransferase"
                     /protein_id="WP_279221954.1"
                     /transl_table=11
                     /translation="MALIRSDLEANRGNVKALAVLPLFRATHAIRQDSRLPRPLRLLTV
                     ATYRFVTEGVLGVELRSGARVGSGLRLDHGVGLVVHDGAVLGSHVLLRHNVTIGVARRG
                     GACPVIGDRVEFGAGAVVVGGITIGEDAHVGANAVVTRDVPPGGKARALPAVITGRGG"
     gene            complement(3765..4634)
                     /locus_tag="CWS50_RS11130"
     CDS             complement(3765..4634)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="CWS50_RS11130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_127842845.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7e-15, bitscore:
                     52.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELSGHVVVSVPTRHCTDHLYQAVRSVLSQTYDDLEVVVVSDGDD
                     DGPWDVLASIKDPRLKRARLTSSRGPYFIHDMVLRSATDARWLLIQDADDWSEECRVAT
                     LLAELMRRPLVGVTSGQFYEGLYQSYATTFCAPLRPDWYLDRARHHGLYSREGLLAAGG
                     YFGGTAYAFDSFIVNSLYVCNALGYVDVPLYHRRRRNGSLSRSRTIGVGSPARADYVER
                     LVHAWRDLLAHAESRSCDKSLLPAVARLVDSLVTSAQRAEQARAVSQLREGMTGLRPGE
                     VLEIGLEQ"
     gene            complement(5557..6664)
                     /locus_tag="CWS50_RS11135"
                     /pseudo=""
     CDS             complement(5557..6664)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011728598.1"
                     /locus_tag="CWS50_RS11135"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MANRPAPGLVLREGNREVLESWTRSRSVRSGLAARSRIVLLAAQG
                     VSNTEIAQRVGSRARRW"
     misc_feature    6666..6681
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.8"
                     /tool="antismash"
     misc_feature    complement(6902..6920)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.55"
                     /tool="antismash"
     gene            complement(7573..8427)
                     /locus_tag="CWS50_RS11140"
     CDS             complement(7573..8427)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CWS50_RS11140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127842846.1"
                     /transl_table=11
                     /translation="MTEAQSSNLKPADRLYLVDLGRRLDDAQAECQRATTAVLNDVDAC
                     DEVCARVLHARGYFRVPTMMCAWLDEDTTTRLAPALAMHIFGMKLMDDTIDGDTPLSRT
                     ELVCASVALCQRATTLLARSAPSAVELLRDLEESLLTVCRQMVAGGRKPPDSVAEWAEA
                     ALGFGGDFLAMYGRLACVAGGRPAAAASAAAAGRALGILIAMSDDWADYEKHHERVGNL
                     RYIVGDDDERRAELLALARKCAREGIDAASAQDPDIDLAPVIRWHLDDLASTVDGLGPV
                     YLR"
     misc_feature    complement(7594..7596)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8424..10004)
                     /locus_tag="CWS50_RS11145"
     CDS             complement(8424..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014589.4"
                     /locus_tag="CWS50_RS11145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbamoyltransferase C-terminal domain-containing
                     protein"
                     /protein_id="WP_127842847.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.2e-13,
                     bitscore: 48.4, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLALHSVGHDSGAAVVEDGRVIYSIETERLTRRRYDHRVDLAI
                     GAVTSQPEHPLNSFDWVALTTPIGHPAATVPDQAQVMERLRGRRELHVETTCEIRGQRL
                     PCIVVTHEVSHAMLAAHYSGYAEDCLVLVNEGQGQFTQNALFTYRDGHLDWVDSDVLPW
                     WGRGLGWTGMGVLFDMGNSPGVAGRLMALSAYGQPDKAIREQLVGIPDRIVTDRSYAYD
                     VATELRDAHFADGFQRRADIICTFQELFTQAVTSTVAEAMERHQCGALALGGGCALNIV
                     TNTALRDIHGLAPSIAPACNDSGHPLGAAAYAWYLLSGSHLLPFSVYNVGVEETPSQRR
                     EALRAGNLTPLAYDEDTVVEVLAEGGVVAMNHGLAESGPRALGHRSLLANPRIKGMKER
                     VSQRLKAREWYRPLAGLMTKERFAEMLPGCPDSPHMLFDYKIPASMMPEARHRDGTSRL
                     QTLSRSSDPVLHSLLTSFSARTGVPGLINTSLNSAGRSIAQTTDDMLTDFLRTEVDLFV
                     SGDFMARQL"
     gene            complement(10001..11092)
                     /locus_tag="CWS50_RS11150"
     CDS             complement(10001..11092)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphoglycolipid: moeGT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="CWS50_RS11150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_127842848.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.9e-06,
                     bitscore: 23.5, seeds: 256, tool: rule-based-clusters)"
                     /sec_met_domain="moeGT (E-value: 3.9e-56, bitscore: 187.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISRGVSDAPNHDRTARYRASGGWRPLAELAIGGDVMMVLPTRPA
                     RLSPEALTDTARELSAQAVAAERAQGYQVALVVVIQYASSQERRLAESHGDALLALDDQ
                     HITTVVASRAGKIAALNTAFRLAAPTVRFVGWVDDDVELGQGTLTRLLQEIRRMPAPAA
                     VGATKVPHRSPHRTSHALARAKGVMPSAMNYPHGCAMIVTADVIGRGIPERYASDDGWV
                     CFQLLDPAADNALWRMRLVPVASVSYIVGGALSSTLRRLRRQRIGQLLLMAEAPAPVSR
                     CYLHHCLLNGVSLLPITLREGRISTTTLERCLYSWVHVLSTLLLAGELALRGLLRLPLS
                     GIGWGSPTTTDRNAVLTTRRNEK"
     gene            complement(11122..11901)
                     /locus_tag="CWS50_RS11155"
     CDS             complement(11122..11901)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphoglycolipid: MoeO5"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014000.4"
                     /locus_tag="CWS50_RS11155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="geranylgeranylglyceryl/heptaprenylglyceryl
                     phosphate synthase"
                     /protein_id="WP_243118567.1"
                     /sec_met_domain="MoeO5 (E-value: 3.4e-65, bitscore: 217.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQGATPGWRARELVTYLHDTTGSAVCIIDPFKLADDEVLERAEAA
                     EELGSPFIVLASTDHPNFRERMTTLVPEVSRAVSVPTLLHFPPTRGEGLPVVQGAAGYL
                     WPALLMSRDPYFVWQSLLESAARWPALLAGATPPEPILCAALTVGPDYLSESVLSTYSL
                     EESRQAVHETACLVRVLGLDMVYLYSRNQRVDPRTCTMFREEILPDQLIFVSGNIRTGE
                     DIAQHLDAGADFVGFAGACEGPDWRERMPDLLTMRSV"
     gene            complement(11907..13064)
                     /locus_tag="CWS50_RS11160"
     CDS             complement(11907..13064)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CWS50_RS11160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_127842850.1"
                     /transl_table=11
                     /translation="MAIVNVYAARTWGAMGNFVAAAHLSRVLARDGRHTVTVTASEDLV
                     PFMRSAGHEIRDINLLANSREELNRTYRGFAGRSAEALPPGFETSRTAPPVDLGGVVQD
                     LERQRPDIAVATKGVIARMLVWAVRETGLSTKIWHYVTNPGLAEMPMHHCPDAHVTSVP
                     WPGNRDRLLQLVALPRASVRVTGPLLAARSMPPAPASSPEPRRPVILLFNNRGGSVFPD
                     AVEHLLRARDDFKVVYLTVDQPSEAAALSKPFVSRGWEIHERLPQERYLQILAEASCSP
                     GSFLVCKASPATVYEAAYQGIPLLALPSGLPQEEWVPEFVLQHDIGRTVYSADELIRCM
                     DLWRVPGATAKIRAACDRFRRTRLNQAQAEENVLRVADDLLLEGV"
     gene            complement(13064..14872)
                     /locus_tag="CWS50_RS11165"
     CDS             complement(13064..14872)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="CWS50_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_164860136.1"
                     /sec_met_domain="GATase_7 (E-value: 2.6e-25, bitscore:
                     86.0, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.6e-57, bitscore:
                     192.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSMEQRGPHGSRVQTLPGHGAFGHMALPLYANATEQPWVADDG
                     TAVTFSGEIYNARELSSEEFGADTRFPGEAPLLALMVKHHGAASLSRLRGMYSIAIWDP
                     QRAELTLARDRLGKKPLYYTWQPSEAGDRGEVVFASVLDALSSGLHDSPPPATEVLTDY
                     VRTRCVPAPGTAFRGVFKIRPGEVMTIRHGKVSALLNRSVRGAGPAPRTPAPDLRTLLA
                     RAIDRRTVPLSQQPGLLFSGGVDSTAVGALLNRVTPRPVDAFCVVSSSEEERWIRLLAD
                     DMGVRVHVEHPNVDDLADESLAALQDLDEPMADPSLVVTRRAARLASCHTEVVLTGDGA
                     DELFYGYRWFEVQHLLHLLRRVPDPVVRQSLLTLGSQRLRGLGLPITPFAADIAASVGA
                     PPDKQFLLAHAGAPPETLLRLLGGSTAVHPEDHRTARSRDDALARSRDGIFRRFLVDLV
                     ITKIDRATMAYGVEARSPFLDEDLVAWGLSLRPTDCRRGRLGKAPVRALVKDLVGRRPA
                     LRRKQGFRAPLAAVLRGPLRPLVESRLASDRLRDTGRWDPVTVDELVRDHMVRGVDRTQ
                     ILWTLLVYESWRERCAQGHEVGVTAP"
     misc_feature    complement(15235..15250)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.18"
                     /tool="antismash"
     misc_feature    15244..15258
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            complement(15437..16655)
                     /locus_tag="CWS50_RS11170"
                     /pseudo=""
     CDS             complement(15437..16655)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017195779.1"
                     /locus_tag="CWS50_RS11170"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGIEDVDVFVGIDVGKAEHWATALTTGGRKVLDKALPNDESRLRG
                     LYERLGSHGRVLVAVDQPATIGALAVAVAQAMGTTVGYLPGLSMRRIADLTPGSARTDA
                     KDAAVIAEAARTTPHTLRSISTSDEDAASLSMLTGFDLDLARQDQPDRKPCPGPVHPDP
                     PSP"
     rRNA            complement(16995..17111)
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CWS50_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="5S ribosomal RNA"
     gene            complement(16995..17111)
                     /gene="rrf"
                     /locus_tag="CWS50_RS11175"
     rRNA            complement(17323..20511)
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="CWS50_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /product="23S ribosomal RNA"
     gene            complement(17323..20511)
                     /locus_tag="CWS50_RS11180"
     misc_feature    complement(18296..18309)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.96"
                     /tool="antismash"
     misc_feature    18446..18455
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    18448..18461
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.03"
                     /tool="antismash"
     misc_feature    18449..18462
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.1"
                     /tool="antismash"
     misc_feature    complement(18451..18464)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.92"
                     /tool="antismash"
     misc_feature    20282..20299
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.75"
                     /tool="antismash"
     misc_feature    complement(21777..21791)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.2"
                     /tool="antismash"
ORIGIN
        1 taggggggta agtaaacgct tcgggcggac ggaggtgttc agggatgtct ccttcacggt
       61 ggcgcctggg cggtccctgg ccgttgtggg ggcgaacggg tgcggcaagt cgacgttgct
      121 gaagatctgc gccggcctcg tgtcccctac cgccggtgag gtgcgtgtga cgggacggct
      181 cgggtactgc ccgcagcacg cggacctcgc gccccgtctc acggcgcagg atcacattac
      241 gtggctcggc agtggtctcg gcctcgccgc cgccgtggca cgacgtcaag gagagcagat
      301 cgcctctgcc ctgcacatga gggactcccg cagacaggtt cgcaggttga gtggcggtac
      361 ggcgcagaag gtcaacctgg tctgctcgat gatgggcggg ccagatgtcc tgctcctgga
      421 cgagccgtac cagggctttg acgagggtgc ctacctggac ttctgggacc tcgtggagtc
      481 ctggtgcagg caggggatcg cggtggtcgt cgtgacgcac atgctgcgcg agctgcaccg
      541 tgtggacttc gtcctcgacc tggggggaag ggccgagtga tgcgagtgct ccgtaccacc
      601 gagatgaccc tgcgcgacct cttcggccga gggtgggtcc tggtgctgct catgctgctg
      661 ccgctcgttt tctacgctgc gcgacgctcg gacgccggct ggcaggcctt gcgcatgggc
      721 tgcatggggc tggcgtgggc tgtggggacg gtctccctgt tcgcacagca aaccgtgaga
      781 gacttggacc cgcgcctgcg tctggccggg gtccgcgcat gggagatctt cgtgggccgg
      841 ctgctggcat tgttgggggt cgccctcgtc gtcggctcgc tatacgccgt agggctcgtg
      901 ctcgaccagg acgtcctgca cgggtggtcg gtcgtcgcgg ccctcctgct gtccgcagcg
      961 ctccccgttc cggtggggat ggtcgtggga ctcctgatcc cccgcgagct tgaggggatg
     1021 ctggtcctca tcatggtcgt cggtctgcag acgatcgtgg acccggggcg ttccctggcc
     1081 gagatactgc ctctgtggtc aacccgtaac ctcctgaact acggtgtcga cggggtgggt
     1141 agtctggagg actcgtggct gcatgccgct gtctacggtg gtgcatgtct gctggtgggt
     1201 ttcgtggtgt cggctgttcg cctgcgcagg cgcaggcacc tggtgcttct gccacgagcg
     1261 caggccttgc cgggctccgg agcccggaca gccggcccgt ccagcggcta agaggaccgg
     1321 gtacccgtgg ccctggccag aggtgtcggc gcgcatgacg ccggtccgtt tcctcggaaa
     1381 ctgagttgat gtgcggcctg gccggcgtcg tcggtgaccc ggacgcacga cagggcctgg
     1441 tggcgatgct cgcgcgtctt gttcatcgtg gacctgatgg ggagggccgg tggcatgagg
     1501 gcggcaccgc ccttggccat cgcccccccg tcgtcggaga cctcggcacc ggaggcgtgc
     1561 agcccgtcgt ctccgccgac ggttcgctcg tgctcgtgtt cgacggccag ctctgcaacc
     1621 gcagggacct tcggcggcag ttcgagggca gggggcacag gttcacgacc cggtgcgacg
     1681 gtgaaatcgt cgtcgccgcg ctgcaggagc acggagtgga tgccctgcgg cggttcgagg
     1741 gcgtgttcac gctggcgtgg tgggaccgtc gggccgggag cctgtggatg gctcgcgatc
     1801 gggtcggtga gaagcccctg tactacctcg aggaccgtgg gcggttcgcc ttcgcctctg
     1861 agatcggtgc cctgactgca ctgggatggg atgacggcgg catagacccg gaggcggtcg
     1921 ctctgctgct ctcccggcgg tgtgtaccgt cgccgtggac gatccatcgc cgcatccgcc
     1981 agttgccacc cggctcggtg ctggagttgt cgagaggccg cacccggatc gcaccgtact
     2041 ggagcgccat cgaggcggtg accacgggcc aggagcgtac gcggatctcc gaccactggg
     2101 aagtggagcg ggcactgcgg agggcggtca gccgccagct ggaagccgac gtccccctcg
     2161 gagtgctcct gtccggcggc acggactcgt cgctggtcgc ggcgctagcg ggcgagcagc
     2221 atgacgcccc tgtcacggcc ttcaccctta gttggcagga ccgggacctt gatgaggcca
     2281 gtgccgccgg ggccactgcc aacgcgctcg ggatggatca cgttgtggtc cctctgaagg
     2341 accctgagct ggtcgacacg gtcctggccg tgcaacgggt cttcggtgag ccgttcgctg
     2401 acccgggcgc ggtgcccctg atggtgctct ccgcctgtgc ggctcagcac gtcacggcct
     2461 gcctgacagg tgatggtggg gacgagtgct ttggtgggta ccgtcgatac tctcgcttgt
     2521 cgagactcgg acgaccggcg tcccgtgcgc acgcgctccg gccgctggtc gagcgcctcc
     2581 cacgcggctt acgctcgtca cgtctacgct tcctgggacg ttccctggcg gagatctaca
     2641 cgctggtgag tgcctcgtgg gacccgctgg tcagcggtga actggcgggg ctcagcgtgc
     2701 caccctatcc tcccacggca gccttcgatg tcagtgatct gagcgtgcgg aggatggcga
     2761 tgctgaccga cttcatggga tatcttcccg accagctcct cgctaagacg gaccgcacct
     2821 gtatggcgaa ctcgctggag gcgcgggcgc ccctgctcga tccctgcgtc gtcaacctgt
     2881 ccttcgccct cgacgacagg ctgatcgtgg gcaagagggt cctgcgggat attgtggcct
     2941 gccgcctgcc tcatctgtcg cggcaggcgg tcaagcgcgg gttcgagacc cctaccgagc
     3001 gttggctgcg tgggcccttg cgcagcctcg tgtcggagac catccgcaag gagtctcttg
     3061 aggcacgggg catcgcacgg ccagagatcg cgctggacat ggttgcgcgc caacgtgcag
     3121 gcgagcccct gtcgcgcatc gtatggcctc tgctgatgct gacgctctgg gagccgggcg
     3181 gcgggccgcg tccctcggcg gccggtctca gccgccacgc ccagtgatga cggcgggaag
     3241 agcgcgggcc ttgcctccgg gtggcacatc acgtgtcacg acggcattcg cgcccacatg
     3301 tgcatcctca ccaatagtga taccaccaac cacaaccgct cctgcgccga actcgaccct
     3361 gtcgccgatg acagggcagg cgcctccgcg ccgggcgaca ccgatcgtca cattgtgccg
     3421 gagcagcacg tggctcccga gcaccgcgcc gtcatgaacc accaatccaa cgccgtgatc
     3481 cagccgtagg cctgacccca cccgcgcgcc agagcgaagt tccacgccca gaacgccctc
     3541 ggtgacgaag cgataggtcg ccacggtcag aaggcggagc ggccgtggca gcctcgagtc
     3601 ctgacggatg gcgtgggtgg ccctgaacag cggcagcaca gccaaggcct tcacgttgcc
     3661 ccggttggcc tccaggtcgg aacggatgag tgccataacg gagggatcgg ccttggtccc
     3721 acggggcctc attgcccgac acaggcggcc gaacacgctg agcgtcactg ttccagcccg
     3781 atctcaagaa cctcgcccgg gcggagcccc gtcatgcctt cgcgcagctg ggacacggca
     3841 cgggcttgtt cggcccgctg ggcggaggtc accaaggaat cgaccagccg tgcgacagcc
     3901 ggcagcaacg acttgtcgca agatcggctc tcggcgtgcg cgagaagatc ccgccaggcg
     3961 tgcacgagac gctctacgta gtccgctcgt gcagggcttc cgactccgat cgtcctcgac
     4021 cgggagagcg agccgttgcg ccgccgtcga tggtacagtg gcacatcaac gtaaccgaga
     4081 gcgttgcaca cgtaaagaga gttgacgata aaactgtcga aggcgtaagc cgtgccgccg
     4141 aagtagccac cagcagcaag caggccctct cgtgagtaca gcccgtgatg gcgagcgcgg
     4201 tccagatacc agtccggtcg cagcggcgcg cagaatgtgg tggcgtagct ctggtacagg
     4261 ccctcgtaga actgtccaga cgtgactccg accaacgggc gacgcatgag ctccgccagg
     4321 agggtcgcga cccgacactc ctccgaccag tcatcggcgt cctgaatgag gagccaccgc
     4381 gcgtccgtgg cggagcgcag gaccatgtca tggatgaagt aggggcctcg ggaggatgtc
     4441 agccgggctc gtttgagacg agggtccttg atcgacgcca ggacgtccca cggcccgtcg
     4501 tcgtccccgt cactaaccac gaccacctcg aggtcatcat aggtctgact cagcacgctc
     4561 ctcaccgctt gatacaggtg gtccgtgcag tgacgggtcg gtacggacac cacaacatga
     4621 cctgacagtt ccatagatat cctttcacaa tgtccgtggc ctctgaggcg gatgtgcaga
     4681 gcatgccaga ccgtgtccga cggagctggt gctacgccgc tcagttcgcg cggtcggcac
     4741 ctgggtcggt tgaagggcag atggtctcca gcagcgtcgt acgggccccg ggtgcggcgt
     4801 caacccgctc gaaaccgccc accgaggtcc gaaaagcgag gtcgactgaa gatggtgctg
     4861 gtagtccgaa aggaggtggt ccttaatgcc gccgacgtga cgctgctgct caacggcgtc
     4921 gtagggagtg ccgcgcagga acatgcgctg gagaggacgt gacgcgctgc tgtcggaatc
     4981 ccaggtggcc ggctgctccg cctcagcggt gacgtggagc atggcgatcg gggtagcccg
     5041 agtgctccat gagcagctcg gcgtacgagg gtctgcaggg cgcttgccag gcgttctggt
     5101 aacggcagac tgcggcccag acgtcagcgg ccgactcgag cttgccgaga tcgagccacg
     5161 agtcgagtgc gcagcagctg ccgaacgcgc atccctccac atcatgctgg tccgccttga
     5221 gggcgccgcc ggagaccggc aggtcctacg tgtacggtgt ggtggaggcg cccgccgcag
     5281 gcgggtggga ccacgtccct tggcatcatc ccagtggccc cttggtagcc ccagggccag
     5341 cggcgtgcga ggggcgcgca gtggagatgc gtcccccgtc agttgattga cgccacatgc
     5401 gtcacgacta gtgcctgaca cctcgacgga ccgagtgatc ccaactgtcc catggtgctg
     5461 gatgcacgac gcgccactcg ctggtacaac gccgtggatc cacaggatca tgatctcatc
     5521 ctcctccgac gtgcaggact cgccgacaac acagccctag tgtcgcgtgc ttgaagttgt
     5581 tggacggttg gctttggtga gtacctgttg ggcggtcctg gtccagatga aggggtgggc
     5641 acgtttgttc caggcgttga cgtaggtgcg gatggtgtgg ttgaggtcct tgaccgacct
     5701 ggacaccgag cgtcgtagcg cctggcgctc caggagggag aaccagacct cgacgaggtt
     5761 cgtccaggag gcgtgggtgg ggtgaagtgg acgtggaagc gtgggttggc ctccagccag
     5821 gcacgtacgt ccttgtgctt gtgggtggcg tagccgtcca tgatcaggtg cagctcgacg
     5881 gggcggccct gctcgtcgac ggcgtcgtgg tgggcccgct cgacctggcg caggaaggcg
     5941 aggagctcct ggtggcggtg cctgggcctg agcgccgcag tgacccggcc ggtggcgacc
     6001 tccagggcgg cgaacagggt ggtggtgccg tgccggtggt agtcgtggga gcggcgcccg
     6061 atccgcccgg gctgcatggg caggaccgga accgtccggt ccagggcctg gatctgggac
     6121 ttctcgtcca cgctgagcac gatcgcgctg gccgggacgt cctcgttcgt gctcaggtag
     6181 agcccgcaga cgtcggtgac cttgccgacg aactcggggg cggtggagaa ccggaaggac
     6241 tgcgcccgcc agggctggat cccgtaggcc cgccaggccc gggccaccgt ggcgggcgag
     6301 acccccaggc ggggtgccag caggcgggtc gaccagtgcg tgatccccaa cgacctcggg
     6361 ggtggggtca gtgtagcggc caccaccctg gcgtggtcga cccggcgggg ccgtcccggg
     6421 cgcggggcgt cgtccagccc ctccaggccc ctggccaggt agcggccccg ccaggtcacc
     6481 accgtctggc gcgagacccc acgcgctggg cgatctcggt gtttgacacg ccctgggccg
     6541 ccagcaggac gatccgcgac ctggcagcca ggccagaccg cacgctgcgc gaccgggtcc
     6601 aggactcaag gacctcacgg ttgccctcac gcagcaccag accaggagca ggacgattcg
     6661 ccatgctccc gatcttttca caacaccaac cgtccaacaa ctaacgacac gcgacactag
     6721 ggttatcagg tcgcggggtc cgctcttaag tcccacgttc atgctggtgc gccgagagct
     6781 tcacgcctgc caccgtatgc agcaggcggc cgtactcttg cacggcgtag tctctccacc
     6841 ggccatacac gtggtggtgt cgaaagtacc gtgaggaact aacgatggac ataacgttgg
     6901 tgatgcgttt ccatacagga gctgaaactg gttcccatcc tcgccatgct ccaatcattg
     6961 atgggtagtc ccccgcacga accacaacgg gacaaacctg aaaaaaagac acccgtgcga
     7021 cccacgggta tggccagtcc gcgacacccg tgacgggtcc gtcgactggg tacgtactga
     7081 tcgccgcacg attgagcata taccccaccg ccccctcggg caggcccaca ggacgacgca
     7141 acaacgggtg cccgaactcc ggcaacgtcc tcagcagggg gtcgcggtag agactcagcg
     7201 ctaccggtct tgcgaacgac aggcgcaaca agcgtcgcaa cacatccccg aagccctcct
     7261 caatctcggc gtcatcctca aggaatactc cccagggctg gtggtcagca tgagccagct
     7321 cgaccgccga gcggtgcgcc aacgctgcgg caacctcccc cggcagaagg gctcggtgct
     7381 tcaggacagc cgatcgggtg gcatcaacaa agtctgcggg caggcgttcc aggagatccc
     7441 tgggacagcc cggagtaagg gtcgggagac atccttggga ccgtaggtca tcaaccagcc
     7501 gtgcgtttct gaggccgtcc ggcgggccta cgatgtatac gtgaggcgac aacgccccta
     7561 cgggatgctg cctcatcgga ggtaaaccgg tcctaaacca tctacagttg aggccaggtc
     7621 gtccagatgc catcgaataa caggggcgag gtcgatgtct gggtcctgcg ccgacgcagc
     7681 gtcgatgcct tcccgggcgc acttcctcgc caaagcgagc agctcagcgc ggcgctcgtc
     7741 gtcgtcgcca acgatatagc gcaggttgcc cacacgttca tggtgcttct catagtccgc
     7801 ccagtcgtca ctcatcgcga tgaggatgcc cagcgctcgg cctgctgcgg ccgcggaggc
     7861 ggccgcagca ggccgccctc ccgccacgca tgccagtcgt ccgtacatgg cgagaaaatc
     7921 tcctccgaat cccaaagcgg cctccgccca ctcagccacc gagtcgggcg gcttgcgtcc
     7981 gcctgccacc atctgtcgac agacagtcag gagagactct tccaagtccc tcagcagctc
     8041 gacagcactt ggggcggacc tggcaagcag cgtagtggcc cgttggcaga gtgccacgga
     8101 cgcacagacg agctctgttc gcgacagggg ggtgtccccg tcgattgtgt cgtccatcag
     8161 cttcattcca aaaatatgca ttgctagcgc tggcgccagc ctggtggtgg tgtcctcatc
     8221 gagccaggca cacatcatcg tgggaacccg aaagtaaccg cgtgcgtgaa gcacgcgcgc
     8281 gcagacttcg tcgcacgcgt ccacatcatt caggactgcg gtcgtcgcgc gctggcattc
     8341 tgcctgcgca tcgtccaggc ggcgaccaag atcaaccagg tagaggcgat cggccggttt
     8401 caggttgctg gactgcgctt cagtcacagc tgcctcgcca tgaagtcgcc actcacgaac
     8461 agatcgactt ccgtccgcag gaagtcggtc agcatgtcgt cggtggtctg agcgattgac
     8521 cgcccagccg aattgaggga ggtgttgatc agtccaggca ctcccgtgcg tgccgaaaaa
     8581 ctcgtaagca ggctatgcag cacaggatcg ctgctccgcg acagggtctg caggcggctc
     8641 gtgccgtcac gatgccgtgc ctccggcatc attgatgctg gaatcttgta gtcgaatagc
     8701 atgtgagggc tgtcggggca tcccggcagc atctcggcga acctctcctt cgtcatcagt
     8761 cccgctagag gacgatacca ctcgcgcgcc ttcagtctct gtgagaccct ctccttcatg
     8821 cctttgatac gaggattggc gagcagtgac ctgtggccga gtgctctcgg cccgctctct
     8881 gcgagaccgt ggttcattgc gacgactcct ccctcggcca gaacctccac cacagtgtcc
     8941 tcgtcgtagg cgagcggagt caggttgcct gcacgaagcg cctcacgacg ctgcgacggc
     9001 gtttcttcga cgccgacgtt gtaaaccgag aagggaagca ggtggcttcc tgatagcagg
     9061 taccaggcgt aggcggcagc acccagaggg tgaccagagt cgttacatgc cggggcgata
     9121 gacggtgcca gtccgtgaat atctcgcagc gcagtgttgg tgacgatatt cagggcgcaa
     9181 ccgcctccca aggccaatgc gccacattga tggcgctcca tcgcctcagc tacggtcgag
     9241 gtgacagcct gggtgaagag ttcctggaag gtgcatatta tgtcggctcg ccgctggaag
     9301 ccgtccgcga agtgggcgtc acgcagctcg gtggcgacgt cgtaggcgta ggagcggtca
     9361 gtgacgatcc tgtccggtat tccgaccagt tgttcgcgaa tagccttgtc aggctggccg
     9421 taagccgaca acgccatcag cctgcccgct acgccggggc tgttccccat gtcgaatagc
     9481 acgcccatgc cggtccagcc aagtccgcgg ccccaccagg gaaggacgtc gctgtcaacc
     9541 cagtccaggt ggccgtcgcg ataggtgaat agggcattct gcgtgaactg tccctgacct
     9601 tcgttcacaa ggaccagaca gtcctcggcg tatccagagt aatgggcggc cagcatcgcg
     9661 tggctgacct cgtgggtgac cactatgcac ggtagtctct gccccctgat ctcacacgtc
     9721 gtctccacgt gaagctcgcg ccgtccccgc aggcgctcca taacctgagc ctgatctggc
     9781 accgtcgccg cgggatgacc gataggtgtt gtcagcgcga cccagtcgaa gctgttcaag
     9841 gggtgctcgg gctgactggt gacagcgcct atggccaagt cgaccctgtg gtcgtatcga
     9901 cgccgagtga gtcgttccgt ctcgatgctg tagataacgc gcccatcctc gactacggcg
     9961 gcgccgctgt cgtgaccaac ggagtgcaaa gcaagaactt tcatttctca ttcctccttg
    10021 ttgtgagaac ggcattccga tcagttgttg tcggacttcc ccacccgatc ccgctgagcg
    10081 ggagcctgag cagtcccctc agggccagct cgccagccag cagaagagtg ctgaggacat
    10141 ggacccacga gtacaggcag cgctcgagtg tcgttgtgct gatccgcccc tcccgcaggg
    10201 tgatcggcag gaggctcacg ccgttcagca ggcagtggtg aaggtagcag cgactgaccg
    10261 gcgccggcgc ctccgccatc agcagcagct gcccgatgcg ttggcgccgc agacgtcgca
    10321 gagttgacga gagagcgcct ccgacgatgt agctgaccga ggctacgggc accaggcgca
    10381 tcctccacag ggcgttgtcc gctgctgggt ccagcagctg gaagcacacc caaccgtcgt
    10441 cgctggcgta gcgctccggt atgccgcgcc ctataacgtc tgccgttacg atcatcgcgc
    10501 acccatgggg atagttcatc gctgatggca tgaccccctt ggctcgcgcc agcgcgtggc
    10561 ttgtccggtg aggtgagcga tgaggtacct tcgtggcacc tactgcagct ggtgctggca
    10621 tgcgtcggat ctcctgcagg aggcgggtga gcgttccctg gcccagctcc acgtcgtcgt
    10681 cgacccaccc cacgaagcgc acggtcggcg ccgcgagccg gaaggcggtg ttgagcgctg
    10741 cgatcttgcc ggccctggag gcgaccacgg tggtgatgtg ctggtcgtca agggcgagga
    10801 gggcgtcccc atgtgactcg gcgagccgtc gctcctggct gctggcgtac tggatgacga
    10861 cgaccagcgc gacctggtac ccctgcgccc tctctgcggc gactgcctgg gccgagagtt
    10921 cgcgagctgt gtccgtgagc gcctctggcg acaggcgtgc gggccgcgtg ggcaggacca
    10981 tcatcacgtc gccccctatc gcgagctcgg cgagcgggcg ccatcctcct gatgcacggt
    11041 accgggccgt cctgtcatgg ttgggtgcgt cggagacacc gcgcgaaatc atgcgacgga
    11101 ggagggcggt gccagccacc gtcacacgct cctcatggtg aggaggtcgg gcatgcgttc
    11161 gcgccagtcg ggtccttcgc aggcgccggc gaaccccacg aagtctgcgc ctgcatccag
    11221 gtgctgcgct atgtcctcgc cggtgcgtat gttgccgctt acgaagatca gctggtcagg
    11281 aagaatctcc tctcggaaca tcgtgcacgt ccgtgggtcc accctctggt tcctcgagta
    11341 gaggtagacc atgtccaggc cgagcactcg cactaggcat gcggtctcat ggacggcctg
    11401 acggctctcc tccaggctgt acgtgctcag gacggactcg ctcaggtagt ccgggcccac
    11461 ggtcagtgcg gcgcacagga tgggctcggg aggcgtggcg ccggccagga gggcgggcca
    11521 ccgggcggct gattccagca ggctctgcca tacgaagtag gggtcccgac tcatgaggag
    11581 cgccggccac aggtatccgg ccgcgccctg gacgacggga aggccttctc cgcgggtcgg
    11641 aggaaaatgc aggagagtcg gcacggagac ggccctgctc acctctggga cgagagtcgt
    11701 catccgttcc ctgaaattgg ggtggtcggt ggaggcgagg acgatgaacg ggctaccgag
    11761 ttcctctgcc gcctccgccc gttccagaac ctcgtcgtcg gccagcttga acgggtcgat
    11821 gatacagact gccgaacctg tggtgtcgtg aagataggtc accagctcgc gagcgcgcca
    11881 ccctggggtc gctccctgca tcaggctcac actccttcga gcagtaggtc gtccgcgacg
    11941 cggaggacgt tctcctccgc ttgcgcctga ttcagccggg tgcggcgaaa acggtcgcac
    12001 gcggctcgga tcttggcggt cgcgccgggt acccgccaga gatccatgca ccggatcagt
    12061 tcatcagcgg agtacaccgt gcggccgata tcgtgttgca ggacgaattc cggcacccac
    12121 tcctcctgcg ggagcccaga gggaagcgcg aggagcggaa ttccctggta ggccgcctcg
    12181 tacacggttg cggggctcgc cttgcacacg aggaaggagc cgggggagca cgatgcttct
    12241 gcgaggattt gcaagtaccg ctcctgcgga agccgttcgt gtatctccca gccccgcgag
    12301 acgaatggct tcgacagagc ggccgcctcg gagggctggt ccacggtgag gtagaccacc
    12361 ttaaagtcgt cccgcgcccg aagaaggtgt tcgacggcgt cagggaagac ggaaccgcct
    12421 cggttgttga atagcaggat gacgggacgt cgcggctcag gggagcttgc cggggcgggc
    12481 ggcatcgaac gggcggcgag caggggacca gtgacacgca cgctggcgcg agggagcgcc
    12541 acgagctgga gcaggcggtc cctgttaccc ggccacggta ccgaggtgac gtgagcgtcc
    12601 gggcagtggt gcatgggcat ctcggctagg ccggggttcg tcacatagtg ccagatcttg
    12661 gtgcttagcc cggtttcccg gaccgcccac accagcatcc tggcgatgac ccccttggtt
    12721 gccacggcga tgtcggggcg ctgccgctcc aggtcctgca ccacgccacc aaggtcgacc
    12781 gggggagccg tccggctggt ctcgaagccc ggcggcagcg cctccgcgga acgacctgcg
    12841 aagccccggt aggtccggtt gagttcctcc cggctgttcg ccaacagatt tatatctcga
    12901 atctcgtgcc cggcgcttcg catgaacggc acaagatcct ccgatgccgt gacggtgact
    12961 gtatggcgtc cgtcgcgagc tagcactcgg ctgaggtggg cagccgccac gaaattgccc
    13021 atggcgcccc aggtgcgcgc ggcgtacacg ttcacgatag ccatcagggc gctgtcaccc
    13081 ccacttcgtg cccttgagcg catctctccc gccaggactc gtacacgagc agcgtccaca
    13141 ggatctgagt ccgatccacc ccgcggacca tgtggtcccg gacgagctcg tcgaccgtga
    13201 cagggtccca ccgtccggtg tcgcgcaagc ggtcgctggc cagccgtgac tcgacgagcg
    13261 ggcgcaaggg gcctcgcagg accgccgcca ggggggcacg aaatccctgt ttcctgcgca
    13321 gcgccgggcg tcgacccacc aggtccttca ccagcgctcg cacgggtgcc ttgcccaacc
    13381 gtcccctacg gcagtccgtg gggcggagcg agagccccca ggcgaccagg tcttcatcca
    13441 ggaaaggtga acgcgcctca acaccatacg ccatggtcgc gcgatcgatc ttcgtgataa
    13501 ccaggtcaac gaggaagcgc cggaatatgc catcgcggga ccgcgccagc gcgtcgtcgc
    13561 ggctgcgggc tgtccggtgg tcctcggggt ggacggcagt ggagccgccg aggagccgga
    13621 ggagggtctc gggtggtgcc cctgcgtgcg ccagcagaaa ttgcttgtcc ggcggggcgc
    13681 cgacgctggc ggcgatgtcg gcggcgaacg gggtgatggg cagtcccagt ccgcgcagcc
    13741 tctgggatcc cagggtgagg agcgactgcc tcacgaccgg gtcgggcacg cggcgcagga
    13801 ggtgcagcag atgctgtacc tcaaaccacc ggtacccgta gaacagctcg tccgcgccgt
    13861 cacccgtcag taccacctct gtgtgacatg aggccagtcg tgcggcacgg cgtgtcacca
    13921 ccagcgacgg gtcggccatg ggctcgtcca ggtcctgcag ggccgctagc gactcgtccg
    13981 cgaggtcgtc cacgttgggg tgctcgacgt ggacacgcac acccatgtcg tcggcgagga
    14041 ggcggatcca gcgctcctcc tccgacgagc tcacgacgca gaaggcgtcg accggtcttg
    14101 gggttactcg gttgaggagc gcaccgactg ccgtcgagtc aacccctccg ctgaacaaca
    14161 gccctggctg ctgcgacagt gggaccgtgc ggcggtctat ggcgcgggcc agcagggtcc
    14221 gaaggtccgg tgccggtgtg cggggtgctg gtccggcccc tcgcacagac cggttgagta
    14281 gcgcggagac ctttccgtgc cgaatcgtca tcacctcgcc ggggcggatc ttgaagactc
    14341 cgcgaaaggc cgtcccgggg gcgggaacgc agcgtgtgcg cacgtagtcg gtgagcacct
    14401 ccgtcgccgg tggcgggctg tcgtgcaggc ccgagctcag ggcgtcgagc acggaggcga
    14461 agaccacctc gccccggtcc ccggcctcgg acggctgcca ggtgtagtag agcggcttct
    14521 tgccgagccg gtctcgtgcc agggtcagct cggcccgctg gggatcccat atcgcgatcg
    14581 agtacatccc gcggagtcgg gacagactcg cagcaccatg gtgcttgacc atgagtgcta
    14641 ggaggggggc ctccccgggg aacctggtgt cggcaccaaa ctcctctgag gacagttcgc
    14701 gcgcgttgta tatctcacca ctgaatgtga cggcggtgcc atcatcggcc acccagggct
    14761 gttccgtcgc gttggcataa agaggcagtg ccatgtgccc gaaggcgccg tgccccggta
    14821 gtgtctggac gcgggagcca tggggccctc gctgctccat gctgtcgagc atggccgtca
    14881 cgcgcggctc agtgtcaggt gacaacctgg gtgtgactat accagcgatt ccgcacatac
    14941 gctccccccg atactcgctg gcggcagctg gacactcccg ttggaggaag gcatcgtgga
    15001 gaaccacccc cggaagtcct ctccgccctg ctggcgccag gacgcccgct caccacgctg
    15061 agccgccagg aagtcaaaca ccacatccgg cagcccccac cagcctgttc gcgctcacgc
    15121 cacccgcctc tcccgctgcg gtctgcgaca ggcgccagta acggggcgcc ggtcacccgg
    15181 aaatgacaaa atacgatacc cacgcggtcg ggcgcgagcg caagaaccca ctctgttttg
    15241 agatgtaaat cacgttcaca tcccaggccg acgcgcagga agcacccacc cacttcccgg
    15301 cagccggtcg ctaccgcgcc ccgccaacca gggaagacag gatggccagg gccgcctccg
    15361 gtgcgtcacg ggctccttgc cgggtgcggg atccaggacg caggtgatca ggcggggggt
    15421 ggccctatgt tgtttgtcaa gcggcggcgg gtagttgttg ggttggttgg ggggtgtaga
    15481 gggcgccgtc tcgggtcatg gcgtagaggg tgaggatgcg gcggtgggcg agggcgggca
    15541 gggcctggtt gtggcgcttg ccctggtctc gtttgcgctg gtagcaggcg cgggatgccg
    15601 ggtctgtcct gagggcggcg aaggccgcta ggaacatggc gcgtttgagc ctcttgctgc
    15661 cggcgtggga gacgtgctca ccgcggacgg aggaccccga ccgccgggtg agtggggtga
    15721 ggcctgcgca ggcaggccag gtgcgcgccg gtgtcgaagg atctgccgag ggtctcggcc
    15781 aggaagacgg cggcggtcct gacccccacc ccgggcaccg gtggccaggg accggcgtga
    15841 ggagggtggg cctccaccag ggcctcaacc tgggcggcga cgtcgtcgcg ctgggcgtgc
    15901 aggaggtggt gagccggacg gggcccgggt ggggcagcac cacgccagcg gcgtcggtgc
    15961 cgacgaccac cactgtctgc ttgcccaggg cgtcggtgat tgtctttgcc caggtggtgt
    16021 gccgtctgca cccgttggct ttgagcttgg cgtcaatacg cgccctgccg gccttcttca
    16081 gtgattgtgg cgtgggccag gcggcgatca cctccagcac ggcgtcgtgc tccagccacg
    16141 gccccagcac agtctcaagg gctgggtgga tctgggtgta caggccccgg acacggtttg
    16201 cggtctggct ggtcctggcg ggccaggtcc aggtcgaaac cggtcaacat cgacaaggag
    16261 gcggcgtcct cgtccgaggt gctgatggac ctgagcgtgt ggggcgtggt gcgggccgcc
    16321 tcggcgatca cggccgcgtc ttttgcgtcg gtcctggcgc tgcctggtgt caggtccgcg
    16381 atgcggcgca tggacaggcc gggcaggtag cccacggtgg tacccatggc ctgggcgacc
    16441 gcgaccgcca gggcgccgat cgtcgccggc tggtcgaccg ccaccaggac tcggccgtgg
    16501 ctgccgagcc gctcgtacag gcctctaagc ctggactcgt cgttgggcag ggccttgtcg
    16561 aggaccttcc tcccgccggt agtcagggcg gtcgcccagt gctcagcctt acccacatca
    16621 ataccgacga agacgtccac gtcctcgata cccattattc tgcgcccttc cgtgtgctgg
    16681 tgggtcagcc tgtcaggcag acggtcccgc acccacgtta cgaaaggact ctagggctaa
    16741 ggtgcctcgg tccgtccccc ttatcagcgg tcaccatccg cccgccacca tgggtgacaa
    16801 taccccccgg atcattgcat agacaggggc aggatatcat acccacagcg gctagcccga
    16861 ccccggacca ccagggacca ccaacaaggt aacgggtgtc ccttgtccct gctggccccc
    16921 cggtgggggg tgtcggtggg gtaaggagcg gggggaggag gccgtggtgg cctcctcccc
    16981 ccgggtgggt gtgtgctcgg tggtgtcctg ctctcccgtc ccctggcggg gacagtacca
    17041 tcggcgctgg caggcttagc ttccgggttc gggatgggac cgggcgtgac cctgccgctg
    17101 tgaccaccga gacgtggtcc gggaccccca accccccctt ctggggggtg ggtgggtgcc
    17161 tggcagccac ccacccaccc ctctgtgtgt gaggggggtg gtggggtggg gtggtcatgg
    17221 accgtacagc gggcgcgccc cccacagtgg ggggggtctg tcgtcgtggt ggcaccagtg
    17281 cgtgctcctg gctggcgcac cagcacgtga ggctgcgcgt gtgggtgctt gtgtcggcct
    17341 gttagtaccg gtcggctcca cgggtcaccc cgcttccacc tccggcctat ccacccagtg
    17401 gtctgctggg ggccttccca ccccgcaagg tggtggagac ctcgtcttga ggctggtttc
    17461 ccgcttagat gccttcagcg gttacccgtc ccgaacgtgg ccaaccagcc gtgcccctgg
    17521 cgggacaact ggcacaccag aggttcgtcc gtcccggtcc tctcgtacta gggacaggcc
    17581 ctctcaggtc tcctgcgcgc gcagaggata gggaccgaac tgtctcacga cgttctaaac
    17641 ccagctcgcg taccgcttta atgggcgaac agcccaaccc ttgggacctg ctccagcccc
    17701 aggatgcgac gagccgacat cgaggtgcca aaccatgccg tcgatatgga ctcttgggca
    17761 ggatcagcct gttatccccg gggtaccttt tatccgttga gcgacggccc acccgcacgg
    17821 ggccgccgga tcactagctc ctactttcgt acctgcccga cccgtcggtc tcgcagtcag
    17881 gcccccttgt gcgcttgcac tcaccacctg gttgccgacc aggctgaggg gacccttgag
    17941 cgcctccgtt accctttagg aggcaaccgc cccagttaaa ctacccacca ggcactgtcc
    18001 ctggcccggg tcacggaccg aggttcaggc gcacgccacg gccagggtgg tatcccaaca
    18061 acggctcacc accacgctgg cgcgcggggg tcacagcctc ccacctatcc tgcacaggcc
    18121 ggggcgggcg ccaataccaa gctgcagtaa aggtcccggg gtctttccgt ccttctgcgc
    18181 gaaacgagca tctttactcg tagtgcaatt tcgccgagct catggtcgag acagcggaga
    18241 agtcgttacg ccattcgtgc aggtcggaac ttacccgaca aggaatttcg ctaccttagg
    18301 atggttatag ttaccaccgc cgttcactgg ggcttggact cgccccttca cccccacacg
    18361 atgagggggc tgagggctcc tcttgacctt ccagcaccgg gcaggcgtca gtccgtatac
    18421 ctcgccttgc ggcttcgcac ggacctgtgt ttttagtaaa cagtcgcttc tccctggtct
    18481 ctgcggccct cacccctagc ccgcgcgggg cctcagggcc cgggcccccc ttctcccgag
    18541 gttacggggg cactttgccg agttccttga ccatgaatca ctcgtgcgcc taggcatgct
    18601 ctgcccgacc acctgtgtcg gtatagggta cgggcggccg gcaccatcgc gtcgaggctt
    18661 ttctcggcac cccaggatca ccctgcttcc cccaccccac cgggcagggt caccatcacg
    18721 cctcaccacc gcccccccac cccaaacggg caggaggacc gccccccgga tttgcctggg
    18781 ggacaggctg cgcgcttgga cgggccaagc catcaggccc gcggaggcta ccactgtgcg
    18841 tcacccctgt taacacgctt gcctaccagc acggagggtc cccgccccca ggccccccca
    18901 cggccacagg ccgccaggag accaccacga ggacaggtca gcacccgcgc gtcagcacgg
    18961 tcggtaccca gccggtacgg gaatgtcaac ccgtcatcca tcgactacgc ctgtcggcct
    19021 cgccttaggc cccgactcac ccagggcgga ctagcctggc cctggaaccc ttggtcattc
    19081 ggcgctaggg cttcccaccc tagtatcgct actcatgcct gcatcctcac tcccgcaccg
    19141 tccacccctg ggtcaccccg gggcttcacc ccgtgcggga cgctccccta ccacccgcca
    19201 ccccttggga ccaccccacc cacaggcagg acagccaggg acacgcgacg ggcccgcggc
    19261 ttcggcggcg cgcttgagcc ccgctacatt gtcggcgcac gaccacttga ccagtgagct
    19321 gttacgcact ccttcgagga tggctgcttc taagccaacc tcctggttgt ctgcgcggcc
    19381 gcacatcctt tcccacttag cgcgcgctta ggggccttag ccggcggtcc gggctgtttc
    19441 cctctcgacc acggagctta tcccccgcgg tctcactgcc acgctccacc ccgacggcat
    19501 tcggagtttg gctgacctca gtaaccctgt ggggcccatc agccacccag tcgctctacc
    19561 tccgccggga accacgcgac gctgcaccaa aatgcatttc ggggagaacc agctatcacg
    19621 gagtctgatt ggcctttcac ccctacccac agctcatccc cccggttttc aacccaggtg
    19681 ggtgcggccc tccacgcgct cttacacgcg cctcagcctg gccatgggta gatcaccccg
    19741 cttcgggtcc acgacgcgcc actgaaccgc ccctgacagg actcgctctc gctacggctg
    19801 ccccccacgg gttaacctcg cgacacgcca ctgactcgca ggctcattct tcaaaaggca
    19861 cgccaccacc ccccaccaca ccggcaggag gctctgacgg ctcgcaggcg cccggtttca
    19921 ggtactcttt cactcccctc ccggggtact tttcaccatt ccctcacggt actgctccgc
    19981 tatcggtcac caggaggtat tcaggcagcc aagcggtctt ggcagactca cacaggactc
    20041 cacggacccc gtgctaccac gggaacccag cccacgcgcg cccagccggc ttcacctacg
    20101 ggggtctcac cctctacgcc tccccttccc agaggactcg gctgccagca cgagcaccac
    20161 gcggccctcc ggcagaagag ccacggccag gccccacaac cccgcacgcg cagcccctgc
    20221 cgggtccacg cacgcgcacg gtttggccct cctccgcttt cgctcgccac tactcacgga
    20281 atatcctctc ctgcgggtac tgagatgttt cacttccccg cgtcaccccc cacgacccgg
    20341 gcacacgccc cggccacggg tggcacgaca cagctcgtgc caggtccccc cattcggaaa
    20401 cccccggatc acagcccgcc agccggctcc ccgaggctta tcgcaggcca ccacgtcctt
    20461 catcggcccc tggtgccaag gcatccaccg agcgcccaca caaacaagca caccacaaca
    20521 cagcacacaa agaacacacc acaccacccg cacccacacg ccccaccacc caggaaccac
    20581 ccaggccagc caggacacgc gcgcgcgggc ggcgaaaatc aacaccacga caggccacca
    20641 caccagcccc ccaccggccc acccaaggac cacgaacccc caacaaacaa cgccagggga
    20701 acaaccagga ggcacagcac ggcagcccga cgctcgcgcc cgctatacag ttcacaacca
    20761 ccccacccac gccccagcca ccacacgcgc acgcgcgcac cagccaggac caggccacca
    20821 ggacgcacag gccccagaac ccgacagcgt gccccgccac caccccagca ccccgcacca
    20881 cagcacgagg ccccagcagc cagcagcaac caccaccccc agcccccaac aacaaggacc
    20941 aggacagcag ccgtcccctc ccacacccgc acggaccacc caccagccac ccccagacca
    21001 ccacaggccc aggaccaggc acccagcagg cagccaccac aactccctag aaaggaggtg
    21061 atccagccgc accttccggt acggctacct tgttacgact tcgtcccaat caccagcccc
    21121 gccttcgacc gctccccgta gggccacggg cttcgggcgt caccggcttt catgacgtga
    21181 cgggcggtgt gtacaaggcc cgagaacgta ttcaccgcag cagtgctgat ctgcgattac
    21241 tagcgactcc ggcttcacgg tgtcgagttg cagacaccga tccgaactga gaccggcttt
    21301 aagggattcg ctccgcctca cggcaccgca gccctctgta ccggccattg tagcatgcgt
    21361 gaagcccagg acataagggg catgatgatt tgacgtcgtc cccaccctcc tccgagttga
    21421 ccccggcagt ctcccgagag tccccaccac cacgtgctgg caacacggga caggggttgc
    21481 gctcgttgcg ggacttaacc caacatctca cgacacgagc tgacgacaac catgcaccac
    21541 ctgtgagggc accccccacc ccaccaaaaa agcggggcag gagaagacca cgtctccgcg
    21601 gcccgcaccc acatgtcaag ccctggtaag gttcttcgcg ttgcatcgaa ttaatccgca
    21661 tgctccgccg cttgtgcggg cccccgtcaa ttcctttgag ttttagcctt gcggccgtac
    21721 tccccaggcg gggcacttaa tgcgttagct gcggcgcggg cgccccggaa aagagccccc
    21781 acacctagtg cccaacgttt acggcgtgga ctaccagggt atctaatcct gttcgctccc
    21841 cacgctttcg ctcctcagcg tcagtaacgg cccagagacc cgccttcgcc accggtgttc
    21901 c
//
