LOCUS       NZ_RYYV01000055         4467 bp    DNA     linear   CON 06-MAY-2024
DEFINITION  Dyella choica strain 4 M-K27 scaffold55, whole genome shotgun
            sequence.
ACCESSION   NZ_RYYV01000055
VERSION     NZ_RYYV01000055.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dyella choica
  ORGANISM  Dyella choica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Rhodanobacteraceae; Dyella.
REFERENCE   1  (bases 1 to 4467)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Dyella dinghuensis sp. nov. DHOA06 and Dyella choica sp. nov.
            4M-K27, isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4467)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135, Xinggang West Road, Guangzhou, Guangdong
            510275, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina Hiseq 4000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003977665.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 01:53:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,733
            CDSs (total)                      :: 4,678
            Genes (coding)                    :: 4,648
            CDSs (with protein)               :: 4,648
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 9 of 30
            Pseudo Genes (incomplete)         :: 25 of 30
            Pseudo Genes (internal stop)      :: 5 of 30
            Pseudo Genes (multiple problems)  :: 9 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:37:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 4467
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYYV01000055.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..4467
                     /collected_by="Li-hong Qiu, Zeng-hong Gao"
                     /collection_date="2015-09-30"
                     /country="China: Guangdong Province, Dinghushan Biosphere
                     Reserve forest"
                     /db_xref="taxon:1927959"
                     /identified_by="Fang-hong Ou, Zeng-hong Gao, Li-hong Qiu"
                     /isolation_source="forest soil"
                     /lat_lon="23.17 N 112.53 E"
                     /mol_type="genomic DNA"
                     /organism="Dyella choica"
                     /strain="4 M-K27"
                     /submitter_seqid="scaffold55"
                     /type_material="type strain of Dyella choica"
     gene            <1..>4467
                     /locus_tag="EKH80_RS23565"
                     /old_locus_tag="EKH80_23560"
     region          1..4467
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="transAT-PKS-like"
                     /region_number="1"
                     /rules="cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS
                     or itr_KS or tra_KS) and not PKS_AT)"
                     /tool="antismash"
     cand_cluster    1..4467
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(ATd and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /kind="single"
                     /product="transAT-PKS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..4467
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[4:>4467](+)"
                     /cutoff="45000"
                     /detection_rule="cds(ATd and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /neighbourhood="20000"
                     /product="transAT-PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5..>4467
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="45000"
                     /detection_rule="cds(ATd and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS) and not PKS_AT)"
                     /neighbourhood="20000"
                     /product="transAT-PKS-like"
                     /protocluster_number="1"
     CDS             5..>4467
                     /NRPS_PKS="Domain: Trans-AT_docking (191-344). E-value:
                     1.6e-49. Score: 160.2. Matches aSDomain:
                     nrpspksdomains_EKH80_RS23565_Trans-AT_docking.1"
                     /NRPS_PKS="Domain: PKS_DH2 (381-601). E-value: 4.5e-53.
                     Score: 172.0. Matches aSDomain:
                     nrpspksdomains_EKH80_RS23565_PKS_DH2.1"
                     /NRPS_PKS="Domain: PKS_KR (812-998). E-value: 2.8e-56.
                     Score: 182.3. Matches aSDomain:
                     nrpspksdomains_EKH80_RS23565_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1076-1154). E-value: 4e-16.
                     Score: 51.1. Matches aSDomain:
                     nrpspksdomains_EKH80_RS23565_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Trans-AT-KS) (1203-1487).
                     E-value: 5.2e-113. Score: 370.0. Matches aSDomain:
                     nrpspksdomains_EKH80_RS23565_PKS_KS.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS-like: ATd"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     transAT-PKS-like: tra_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012337.4"
                     /locus_tag="EKH80_RS23565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_23560"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_126687240.1"
                     /sec_met_domain="ATd (E-value: 2.6e-51, bitscore: 160.2,
                     seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 9.9e-51, bitscore:
                     158.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-15, bitscore:
                     42.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="tra_KS (E-value: 5e-133, bitscore: 430.1,
                     seeds: 44, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.7e-90, bitscore:
                     289.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVIRATAINHGGKTNGYTVPNPNAQAKVIERALRDGGVDARAIS
                     YIEAHGTGTSLGDPIEIAGLSKAFGQWTQARQYCAIGSAKSNIGHCESAAGIAGVTKVL
                     LQLKHRQLAPSLHSSVLNPNIDFTATPFVVQQTLAPWERPVVEKDGVTRTYPRIAGISS
                     FGAGGANAHVVIEEYDAPARTDVAQSGSALVVLSARNEEQLRQQVVQLSAFLEARKNDA
                     SLRLDELAYTLQVGREAMDERLGVAVHTLGELRSALAGYLAGEAEQQEIYRGQVRRTKE
                     ALSTLVGDEGTEALLSGWMTQGKHGKLLDLWVKGLPVAWKALYSQAPRRISLPTYPFAR
                     ERYWLDTEAARDTATAPATAVLHPLVHRNTSNFSLQRFSSRFSGEEFFLADHVVRESRV
                     LPGVAQLEMVRHAASEAMGEACALELRDIEWKRPVIVGEEGLDLHIALTPLDRGEIGFE
                     LYRDNEDGDALIYSQGIVIALADAQPEVAAHNLALLREQCPSSMGAAQCYAAFAEAGLR
                     YGPAFQALNELYIAPQHVLARIALPATVQATQDDYLLHPSVLDAAWQAALGCMPTIGQR
                     LWLPAALGSLEMLAPCAAAMWAVVRHGAVDAERETSRVFDIDLCDEAGVVCIRFGRLEL
                     RLATTVAEPVESFQTLLMHPSWKGLPIGDERLSKHAFAQQRVLLCGVHAQIPDVIQLPL
                     AAGGDVARGYEAAAIALLELLQGLNGQPGQHLIQVVAPAEGEGALLAGLGGMLRTAQLE
                     NPRLVGQVIQVESGQDVARALAENRNTQASHIRYAKGVRSIAGWSELPVQAATSPWKDR
                     GVYLITGGAGGLGLIFAREIARQAKNATLILTGRSLQDEKIHAHVRELETLGAVVRYHA
                     VDVADKAALTQLVHSIPEEHESLDGIIHSAGVLRDSFLIRKAPQQLREVFSAKVAGTLN
                     LDEASAQIALDCFIVFSSITAAIGNVGQADYAAANAFMDAFAHHRNEQVAAGQRRGRTL
                     AVNWPLWAEGGMQVDDATRTHMLREIGMVPMRTANGCAALAQAWSSSSAQVLVVEGVAH
                     RLKAALSVKAVSVEPAAAPADSGHTLPAAEDLREKTLRHLARTLSTTLKLSADKIDASA
                     PMEVYGIDSVMVMDLTARLEKIFGALPKTLFFEYQTLAALADYFLQHHHAALVELLGEK
                     ATAAAVVAKTHPHAKSVAASSVRSRFMPRHAPQDNGAIAIIGLSGRYPQANDVESFWAN
                     LSGGKDSITEIPLERWDWRRYYDADRSKTGTTYSKWGGFLDEVDKFDPLFFNISPREAA
                     LIDPQERLFLECVHGALEDAGYTRESAAAEGNVGVFVGAMYEEYQLFGAQAQAQGQNLA
                     VSNSAASIANRISYYCNFHGPSLALDTMCSSSLTAIHLACQSLRQGGCAVAVAGGVNVS
                     IHPNKYLMLAQGKFISGKGRCESFGEGGEGYVPGEGVGAVLLKPLAQAVADGDHIYGVI
                     RATAINHGGKTNGYTVPNPNAQAKVIE"
     CDS_motif       142..189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0001"
                     /evalue="1.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="61"
                     /protein_start="45"
                     /score="14.1"
                     /tool="antismash"
                     /translation="YIEAHGTGTSLGDPIE"
     CDS_motif       250..294
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0002"
                     /evalue="2.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="96"
                     /protein_start="81"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSAKSNIGHCESAAG"
     aSDomain        580..1038
                     /aSDomain="Trans-AT_docking"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS23565_Trans-AT_docking.1
                     "
                     /evalue="1.60E-49"
                     /label="EKH80_RS23565_Trans-AT_docking.1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="344"
                     /protein_start="191"
                     /score="160.2"
                     /tool="antismash"
                     /translation="ALVVLSARNEEQLRQQVVQLSAFLEARKNDASLRLDELAYTLQVG
                     REAMDERLGVAVHTLGELRSALAGYLAGEAEQQEIYRGQVRRTKEALSTLVGDEGTEAL
                     LSGWMTQGKHGKLLDLWVKGLPVAWKALYSQAPRRISLPTYPFARERYW"
     aSModule        580..3468
                     /domains="nrpspksdomains_EKH80_RS23565_Trans-AT_docking.1"
                     /domains="nrpspksdomains_EKH80_RS23565_PKS_DH2.1"
                     /domains="nrpspksdomains_EKH80_RS23565_PKS_KR.1"
                     /domains="nrpspksdomains_EKH80_RS23565_PKS_PP.1"
                     /incomplete
                     /locus_tags="EKH80_RS23565"
                     /tool="antismash"
                     /type="pks"
     aSDomain        1150..1809
                     /aSDomain="PKS_DH2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS23565_PKS_DH2.1"
                     /evalue="4.50E-53"
                     /label="EKH80_RS23565_PKS_DH2.1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="601"
                     /protein_start="381"
                     /score="172.0"
                     /tool="antismash"
                     /translation="FSGEEFFLADHVVRESRVLPGVAQLEMVRHAASEAMGEACALELR
                     DIEWKRPVIVGEEGLDLHIALTPLDRGEIGFELYRDNEDGDALIYSQGIVIALADAQPE
                     VAAHNLALLREQCPSSMGAAQCYAAFAEAGLRYGPAFQALNELYIAPQHVLARIALPAT
                     VQATQDDYLLHPSVLDAAWQAALGCMPTIGQRLWLPAALGSLEMLAPCAAAMWAVVR"
     CDS_motif       1168..1245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0003"
                     /evalue="2.20E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="413"
                     /protein_start="387"
                     /score="26.6"
                     /tool="antismash"
                     /translation="FLADHVVRESRVLPGVAQLEMVRHAA"
     aSDomain        2443..3000
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS23565_PKS_KR.1"
                     /evalue="2.80E-56"
                     /label="EKH80_RS23565_PKS_KR.1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="998"
                     /protein_start="812"
                     /score="182.3"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GVYLITGGAGGLGLIFAREIARQAKNATLILTGRSLQDEKIHAHV
                     RELETLGAVVRYHAVDVADKAALTQLVHSIPEEHESLDGIIHSAGVLRDSFLIRKAPQQ
                     LREVFSAKVAGTLNLDEASAQIALDCFIVFSSITAAIGNVGQADYAAANAFMDAFAHHR
                     NEQVAAGQRRGRTLAVNWPLWAE"
     CDS_motif       2446..2547
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0004"
                     /evalue="1.10E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="847"
                     /protein_start="813"
                     /score="34.0"
                     /tool="antismash"
                     /translation="VYLITGGAGGLGLIFAREIARQAKNATLILTGRS"
     CDS_motif       2824..2931
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0005"
                     /evalue="1.30E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="975"
                     /protein_start="939"
                     /score="69.2"
                     /tool="antismash"
                     /translation="LDCFIVFSSITAAIGNVGQADYAAANAFMDAFAHHR"
     aSDomain        3235..3468
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS23565_PKS_PP.1"
                     /evalue="4.00E-16"
                     /label="EKH80_RS23565_PKS_PP.1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="1154"
                     /protein_start="1076"
                     /score="51.1"
                     /tool="antismash"
                     /translation="AEDLREKTLRHLARTLSTTLKLSADKIDASAPMEVYGIDSVMVMD
                     LTARLEKIFGALPKTLFFEYQTLAALADYFLQH"
     aSDomain        3616..>4467
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS23565_PKS_KS.1"
                     /domain_subtypes="Trans-AT-KS"
                     /evalue="5.20E-113"
                     /label="EKH80_RS23565_PKS_KS.1"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="1487"
                     /protein_start="1203"
                     /score="370.0"
                     /specificity="transATor: (unknown)"
                     /tool="antismash"
                     /translation="IAIIGLSGRYPQANDVESFWANLSGGKDSITEIPLERWDWRRYYD
                     ADRSKTGTTYSKWGGFLDEVDKFDPLFFNISPREAALIDPQERLFLECVHGALEDAGYT
                     RESAAAEGNVGVFVGAMYEEYQLFGAQAQAQGQNLAVSNSAASIANRISYYCNFHGPSL
                     ALDTMCSSSLTAIHLACQSLRQGGCAVAVAGGVNVSIHPNKYLMLAQGKFISGKGRCES
                     FGEGGEGYVPGEGVGAVLLKPLAQAVADGDHIYGVIRATAINHGGKTNGYTVPNPNAQA
                     KVI"
     CDS_motif       4093..4140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS23565_0006"
                     /evalue="2.60E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="EKH80_RS23565"
                     /protein_end="1378"
                     /protein_start="1362"
                     /score="16.4"
                     /tool="antismash"
                     /translation="GPSLALDTMCSSSLTA"
ORIGIN
        1 tctatggcgt gattcgcgcg acggcgatca accacggcgg caagaccaac ggctacacgg
       61 tgccgaaccc gaacgcccag gcgaaggtga tcgagcgggc gttgcgcgat ggcggcgtgg
      121 acgcacgtgc gatcagttat atcgaagcgc atggcaccgg caccagcctg ggcgatccga
      181 tcgagatcgc gggcttgagc aaggcgttcg ggcaatggac gcaggcccgt cagtactgcg
      241 cgatcggttc agccaagtcg aatatcgggc attgcgaaag cgcggcgggc attgcgggcg
      301 tcaccaaggt gctgctgcag ctcaagcacc ggcagctggc ccccagcctg cattcgagtg
      361 tgctcaatcc gaacatcgac ttcaccgcca cgcccttcgt ggtgcagcag acgctggccc
      421 cgtgggagcg gccagtggtg gaaaaagatg gcgtcacgcg cacctatccg cgcatcgcgg
      481 ggatctcctc cttcggcgca ggcggtgcga atgcgcacgt agtgatcgag gagtatgacg
      541 cgccggcacg cacagatgtc gctcaatcag gctcggcatt ggtcgtactg tcggctcgta
      601 acgaggaaca actgcggcaa caagtggttc agctgtcggc cttcctggag gcaagaaaga
      661 acgatgcctc gctgcgcctg gacgaactcg cctatacgct gcaggtaggg cgcgaggcga
      721 tggatgagcg tcttggcgta gcggtgcata cgctgggtga gcttcgttcg gccttggccg
      781 gatacctggc gggcgaagcg gagcagcaag aaatctaccg cggccaggtg aggcggacga
      841 aggaggcgct cagtacgctc gtcggcgatg aaggaaccga ggctttgctg tccggctgga
      901 tgacccaagg caagcacggc aaattgctgg acctgtgggt gaagggtctg ccggtggcat
      961 ggaaggctct ttatagccaa gcaccacggc gtatcagcct gccgacctat cccttcgccc
     1021 gcgagcggta ctggctcgat accgaagccg cgcgggatac ggcgaccgcg ccagctacag
     1081 cggtgctgca tccgctcgtg caccgcaata cctcgaactt ctcactgcaa cgtttcagct
     1141 cccgtttcag cggcgaagaa ttctttctgg ccgaccacgt cgtgcgggag tcgcgcgtac
     1201 tgcccggtgt ggcgcagttg gaaatggtgc gccatgcagc cagtgaagcc atgggagagg
     1261 cttgcgcact tgagctgcgg gatatcgagt ggaagcgtcc ggtcatcgtc ggcgaagaag
     1321 ggcttgacct gcatatcgca ttgacgccgc tggaccgagg cgaaatcggc ttcgagcttt
     1381 accgcgacaa cgaagacggc gacgcgttga tctatagcca gggcatcgtg atcgcactgg
     1441 ccgatgcgca gcccgaagtg gcggcgcaca accttgccct cttgcgcgaa caatgcccat
     1501 cgtcaatggg cgcggcgcaa tgctatgcgg cgttcgcgga agcaggcctg cggtatggtc
     1561 ctgctttcca ggccctgaac gagctgtaca tcgcgccaca acacgtgctg gcgcgcattg
     1621 cattgccggc aacagtgcag gcgactcagg atgattatct tctgcatccc agcgtactgg
     1681 acgcggcgtg gcaggccgct ctcggttgca tgcccaccat cgggcagcgc ttgtggttgc
     1741 ctgcagccct gggctcgctg gagatgctgg cgccttgcgc cgccgctatg tgggcggtgg
     1801 tgcgccatgg tgccgtcgac gccgaacgtg agacgtcgcg ggtcttcgat attgatctgt
     1861 gcgatgaggc aggggtcgta tgcatccgct tcggtcggct tgagctgcgc ttggcgacca
     1921 ccgtcgccga gccggtcgag tctttccaga ccttgctgat gcatccttcg tggaaggggc
     1981 tgccgatcgg cgatgagcgc ctttcgaagc atgcgttcgc tcagcagcgg gtgttgctgt
     2041 gcggtgtgca tgcccagata ccggacgtaa tccagttgcc tctcgccgct ggtggcgacg
     2101 tcgcgcgcgg ctacgaagcg gcggccatcg cgttgctgga attgctgcag ggactgaatg
     2161 gacagccggg ccagcatctg attcaagtcg tggcgccggc ggaaggcgag ggtgccttgc
     2221 tggctgggct tggcggcatg ttgcggaccg cgcagctgga gaatccacgc ctggtcggcc
     2281 aggtcatcca ggtcgagtcc gggcaggacg tcgcgcgggc gctggccgaa aaccggaaca
     2341 cccaggcatc gcatatccgc tatgcgaagg gcgtacgctc gatcgccggc tggagcgagc
     2401 tgccggtgca agcggcgacg tcgccgtgga aggatcgcgg cgtctatttg attaccggcg
     2461 gcgcaggcgg gttgggcctg atcttcgcgc gcgagatcgc gcggcaggcg aagaacgcca
     2521 ccttgatcct gaccgggcgc tccctgcagg acgaaaagat ccatgcgcac gtgcgcgaac
     2581 tggagacgct cggcgcggtg gtgcgctatc acgcggttga cgtcgccgac aaagccgcgc
     2641 tgacgcagtt ggtgcacagc atcccggaag agcatgaaag cctggatggc atcatccaca
     2701 gcgcaggcgt gctgcgcgac agcttcctga tccgcaaggc accgcagcag ttgcgtgaag
     2761 ttttcagcgc gaaggtcgcc ggcacgctga acctggatga ggccagcgcg cagatcgcgc
     2821 tggactgctt catcgtgttc tcttcgatca ccgctgcgat cggcaacgtc gggcaggcgg
     2881 actatgcggc ggcgaacgcc ttcatggatg ctttcgcgca ccatcgcaac gagcaggttg
     2941 ccgcaggtca acgccgcgga cgcacgctgg ccgtgaactg gccgctgtgg gctgaaggcg
     3001 gtatgcaggt cgatgacgcc acgcgcacgc acatgctgcg cgagatcggc atggtgccga
     3061 tgcgcaccgc caacggttgc gcggccctgg cgcaagcctg gtcaagcagt tcggcacagg
     3121 tgttggtggt ggagggcgtg gcgcaccggt tgaaggctgc cctttcggtc aaggcggtat
     3181 cggtggagcc cgctgccgct ccggccgaca gcgggcacac gctgcctgca gccgaagact
     3241 tgcgcgaaaa aaccttgcgg catctggcac gcacgctgtc gacaaccctc aagctgtcgg
     3301 cagacaagat cgatgccagc gcgccaatgg aggtgtacgg catcgattcg gtgatggtca
     3361 tggatctgac cgccaggctg gagaagatat tcggtgcgtt gccgaagacg ctattcttcg
     3421 agtaccagac cctcgccgcc ctggccgatt atttcctgca gcatcatcac gctgcgctgg
     3481 tcgagttgct tggcgaaaaa gcgaccgccg ccgccgtagt ggcgaagacg catccccacg
     3541 cgaagagcgt ggcggcgtcc agcgttcgat cgcgtttcat gccgcgtcac gcgccgcagg
     3601 acaatggcgc cattgcgatc atcggcctgt ccggccgcta tccgcaggcg aacgacgtgg
     3661 agtcgttctg ggccaacctc agcggcggca aggacagcat caccgagatc ccgctggaac
     3721 gctgggactg gcggcgctac tacgacgccg accgtagcaa gactggcacc acctacagca
     3781 aatggggcgg cttcctcgac gaggtcgaca agttcgaccc gctgttcttc aacatctcgc
     3841 cacgcgaggc ggcgttgatc gatccgcagg aaaggctgtt cctggaatgc gtgcacgggg
     3901 cgctggaaga cgctggctac acacgcgaaa gcgccgcggc cgaaggcaac gtcggtgtgt
     3961 tcgtgggtgc gatgtacgag gaataccagt tattcggtgc gcaagcacaa gcccagggac
     4021 agaacctggc tgtgtcaaac agtgcagcgt cgatcgccaa ccgcatctcg tactactgca
     4081 acttccatgg tccgagcctg gcgctggaca cgatgtgctc ctcgtcgctg acggccatcc
     4141 acctggcgtg tcaaagcctg agacaaggcg gttgcgctgt ggctgtcgcc ggtggcgtga
     4201 acgtatcgat ccatccaaac aagtacctga tgctggcgca gggcaagttc atttcgggca
     4261 aggggcgctg cgaaagcttc ggcgagggcg gcgaaggcta tgtgccgggc gagggcgtgg
     4321 gtgcggtgct gctcaagccg ctggcgcagg cggtggccga tggcgaccat atctatggcg
     4381 tgattcgcgc gacggcgatc aaccacggcg gcaagaccaa cggctacacg gtgccgaacc
     4441 cgaacgccca ggcgaaggtg atcgagc
//
