LOCUS       NZ_RYYV01000026        19358 bp    DNA     linear   CON 06-MAY-2024
DEFINITION  Dyella choica strain 4 M-K27 scaffold26, whole genome shotgun
            sequence.
ACCESSION   NZ_RYYV01000026
VERSION     NZ_RYYV01000026.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dyella choica
  ORGANISM  Dyella choica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Rhodanobacteraceae; Dyella.
REFERENCE   1  (bases 1 to 52734)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Dyella dinghuensis sp. nov. DHOA06 and Dyella choica sp. nov.
            4M-K27, isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 52734)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135, Xinggang West Road, Guangzhou, Guangdong
            510275, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina Hiseq 4000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003977665.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 01:53:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,733
            CDSs (total)                      :: 4,678
            Genes (coding)                    :: 4,648
            CDSs (with protein)               :: 4,648
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 9 of 30
            Pseudo Genes (incomplete)         :: 25 of 30
            Pseudo Genes (internal stop)      :: 5 of 30
            Pseudo Genes (multiple problems)  :: 9 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:37:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 33376
            Orig. end                         :: 52734
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYYV01000026.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..19358
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..19358
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..19358
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:11029](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    127..143
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 23.45"
                     /tool="antismash"
     misc_feature    complement(198..211)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     gene            complement(260..2611)
                     /locus_tag="EKH80_RS21180"
                     /old_locus_tag="EKH80_21185"
     CDS             complement(260..2611)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008212983.1"
                     /locus_tag="EKH80_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21185"
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="WP_126686794.1"
                     /transl_table=11
                     /translation="MTTLRHLAVFGLLIASMFHPVRADQTQVRFQLDHADARGIELKAG
                     NDQITVRFVAPNVVQIHGMPHGASTRPGIVMDPHGSRDTLANLRVRTTAGMASVASGEL
                     TATWDKQAGHLSVADAQGRVLLWTDPATLVDRRIGLQHDVGDPLYGIGGYDAFEPAKGG
                     LLRHGVQIAKAGEQGYPGGPFVWSTHGYGVLVDTVGAKFDLAEGRIDVSGISRGDASFD
                     VIAGTPPQIFAALATLSGPAPLFPKWAMGFTNSQWGIDQQELLAIVHGYRSRHIPIDNF
                     TFDFDWKAWGEDNYGEFRWNKSKFPGGSNGQLKTVMDQLGMHMTGIMKPRIHVDTVEGR
                     YVETHGLWAASRPQNTDYFSLKPVRDVDFDRAAAREWFFNDALKHSFDTGIVGWWNDEA
                     DDTNSNTQFLNMQRALYEGQRAYTPTRVWSINRDFYLGAQRYAYGLWSGDIDTGFDSMA
                     AQRQRMLSAIDVGEMKWGMDSGGFKGHPDNENYARWIEFAAFVPIFRVHGTLGEKRQPW
                     VYGPVAEKAATDAMRLRYALIPYIYSYERAATTEGVGIVRPLSFDYPDDSQVRDDVDAW
                     MFGAGLLVSPVVEKGQTDKLIYLPAGQWTDYFTGKRYQGGETIHYAIDSQTWDDIPLFV
                     REGAIIPNQPATDFVGEQPVPELTVDVFPAEHSTHFDYYDDDGDTYAYEHDVFYSQRLS
                     TQRRGDGVEFGVEAARGSYKPGLKYFLVKVHGVNATSAGALKSYANAEALQTAKGEGWA
                     VGHDRYGDVTLLRLAAQKARRVVLRAADSH"
     gene            complement(2798..4363)
                     /locus_tag="EKH80_RS21185"
                     /old_locus_tag="EKH80_21190"
     CDS             complement(2798..4363)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015448585.1"
                     /locus_tag="EKH80_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21190"
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="WP_230473866.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.2e-93, bitscore:
                     305.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKFRTALRSVLLAAMLALLSLPAVAQEKAAAKPAATASGVYYEI
                     FVRAFYDSNDDGIGDLNGVTAKLDYIKSLGVSGIWLMPINPSPSYHGYDITDYEGINPQ
                     YGNLQDFRKLLAEAHKRGIQVVMDMVINHTSDQHPWFKAAMDPKDPHHDWYLWAKPGTD
                     LKAVSAVGGPAWHRASNGAYYEGTFTAAMPDLNYDHPAVRKAMIEVGRFWLQQGVDGFR
                     LDAAQHIYDDLRTDMSDPIALQKNVRWWSEYRRALEAAKPQVWLVGEVARQNPDDLTPY
                     MGPLNTVFDFPLATQLIESVDQERNLGIGGGLEYSFAAFRKHANGEFDDAPFLSNHDQQ
                     RVMSQLDGNILHMRLAAELLLTLPGHPFIYYGEELGMQGSKPDEDIREPMRWYRNGKGQ
                     GTASWKDWSSGDDATVSVQAQDADPASLLNLYRKLIGWRQQVSALRDGVLHDVPAADPH
                     VLAYMLQDAQSRVLVVHNLSREPRVFELGSDAHVASVLLQTEEGAVLAGGKLSLPPYAT
                     VILQ"
     gene            complement(4540..7407)
                     /locus_tag="EKH80_RS21190"
                     /old_locus_tag="EKH80_21195"
     CDS             complement(4540..7407)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01782.1"
                     /locus_tag="EKH80_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21195"
                     /product="TonB-dependent receptor"
                     /protein_id="WP_126686795.1"
                     /transl_table=11
                     /translation="MILKRNLLVMALASAGLTMAFGVQAATDETGAQTAADTAQQSNTA
                     STSQATTNPKSQQELAKSLSTVTVTGFSSSVEKSIDYQRYADTIQSVVTSADIGGLPDQ
                     SIADSLTHLPGVSAERIAGQASQINIRGLSGDFIQTTLDGREQPSTSGTNYIEFDQYPS
                     ELINMATVYKTSQASLVTGGVAGTIALQTANPLENSKDQSLNIDTRGSYDGQAHDVPGA
                     NAVGYRLSVAYQGKFLDNTLGVGLGFADMYQPHVSEQFVGESSDGSLYTLNKNNPAQQA
                     YLPEGYQLQQNGGEERRRGYLGTVVWRPTKDLQLTADTFFSKFNDSSFGYGFRSQNFYG
                     NNAQITNPVLSSLGTVIGGTASGTGTTQFSNETTADNYTKNTSVFSGGLNMKWNHGNWH
                     IDSDISLSRATSNEINVDTTADPYSGLGTASPQLMAQSTTFQFKGRNIGDVSVSNPGLY
                     TNLNDMALSRYGVYPYIYHDKDKAFRTAVQYDLPNNPVFSAIEAGFYLNNHTYAQDREV
                     YVYGSEWNTSPVAGELPLTIPSSAAQTTCWKGKFSGFPCFLTLNGPAILAAHGIVANPV
                     KNITDQSWSEIQSGSVNEKTRDVFVMGDIDSQLFGHELTGNVGVRVSRQAQYSYGLQQV
                     GNGAGVLIVDGNGNSSRDYAPIKSGKTYTDYLPSFNLIYHWTDQDQMRVAASKVLSRPP
                     INTMLAGAGSWVSNGQYNVWGGTSPLLNPLRATQYDVDYEHYFDDSTGAVTAGVFFKKV
                     NSFIQNVTYNNFDFAAAGIKVPTNPATGQPYANGQYQTSYNAKGGDVRGVEASFTKTHF
                     LPGIWSGLGFDANLALTNSNVHNPTTLAGPTTYIGLPGLSKRVASAAVFYDNGTFSARL
                     SANYRSSFLSDTQIAVDHQLVTFAAETVYDFQASYNITKQLSVVYQMLNLSNQPTKTYF
                     GGNPQQTGTIQYFGRTSYLGVNFKL"
     misc_feature    complement(7555..7568)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    7745..7758
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    complement(7959..7970)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.31"
                     /tool="antismash"
     gene            7972..9588
                     /locus_tag="EKH80_RS21195"
                     /old_locus_tag="EKH80_21200"
     CDS             7972..9588
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257: Alpha-glucosidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015448582.1"
                     /locus_tag="EKH80_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21200"
                     /product="alpha-glucosidase"
                     /protein_id="WP_126686796.1"
                     /sec_met_domain="Alpha-amylase (E-value: 1.5e-82, bitscore:
                     269.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVSWWRGAVIYQIYPRSFLDTNGDGVGDLPGIIQRLDYVASLG
                     VDAIWVAPFFRSPMADFGYDIADYRDVDPLFGTLEDFDSLLAKAHGLGLKVMIDQVLSH
                     TSDQHAWFKESRESLGNAKADWYVWADAKPDGSPPNNWLSIFGGSAWQWEPRRGQYYLH
                     NFLASQPDLNFHHPEVRTAVLDNVRFWLDKGVDGLRLDAINFCFHDRQLRDNPPKPKER
                     RVGRGFSPDNPYAFQYHLYNNTQPENLDFLGDLRALLDRYPSAVTLGEISSEDSLATMA
                     EYTRGHRLHMGYSFELLSSDFSAAYIRRTVAQLEAQVSEGWPCWAISNHDVERVLTRWG
                     NGNTSPRLANLLTAMLCSLRGSVCVYQGEELGLTEAEVPFEALRDPYGITFWPNFKGRD
                     GCRTPMPWNEGPFAGFSPVAPWLPIDEAHKALAVTHQEANANSVLHGFRRFMHWRAAQS
                     ALRQGDIRFLDVPEPILAFVRHDGSGQVLAAFNLGKLPQTVALAGFDAATPLEGHGLQQ
                     GTLQSGQLELPGHGVLFARIA"
     gene            10001..11029
                     /locus_tag="EKH80_RS21200"
                     /old_locus_tag="EKH80_21205"
     CDS             10001..11029
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="EKH80_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21205"
                     /product="sesquiterpene cyclase"
                     /protein_id="WP_126686797.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-60, bitscore: 197.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRFESLPANYAPFAAPLEYEAPNGLRLPNLHYPWASACSPHAPF
                     VEARMQQWLVQHGLIPNEHYRARIAQAKFGWLAARCHPYASLERLQTIAYFYAWYFLVD
                     DWFVGRTEKVSAYTISNLEAVIDVLDIGRIGNEPVYGETAWVDLCRQLRLSMSDAQFER
                     FAHAMHLWVGMAGLRMLEHSHARTAPAHRHEAILRHAGGLYPCLYLIDFANGLPLAQEE
                     HDQVDVQQLRRHTNRVVCWSSDVQHLGLDVHQSAPHRNTVALYASQGYSLQRSLDRVGE
                     RIRTEIDAFMVAASAVREDAGPALSSYIRGLKHWMSGYRDWLASQHGMRAFTETEAAIK
                     AW"
     gene            11497..12999
                     /locus_tag="EKH80_RS21205"
                     /old_locus_tag="EKH80_21210"
     CDS             11497..12999
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013333.4"
                     /locus_tag="EKH80_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21210"
                     /product="hypothetical protein"
                     /protein_id="WP_230473867.1"
                     /transl_table=11
                     /translation="MNTANDTAARRNPGVSGMSLYVPRPRVSLRDWCEWTGNSWDKVQA
                     VVGRSFRQPAPYEDAYTMAATAVLRLICQYNIDPRNVGQLALGTESSKDNSAGAVIVRG
                     MVDRELERLGLPRLSRQLEVPEFKHACLGGVYALKSALRYVGFDANGRQAIVVCSDIAA
                     YERGSSGEQTQGAGAVAMLVEAQPKLFEVDLAHAGSASDYRGPDFRKPFLRHFHHEYGQ
                     RHRRLHDFPIFSGKYSTFAYLDEVGQATDAMIQRLGVSDLDLLESAGGLFFHRPYHMMP
                     LQALAFIYARALARAPQPHAGFQALCELSGVSPDGVVAECRNTPDLYGEFVRQGAHADA
                     AQDAHPLTTKLSGVVRKSPAFQQLLATRVNQGTDWAMELGNLYTAALPAWIAAGFEQAL
                     ESNVEWTDARLYAIGYGSGDASEAIPLRVVPGWREAAAKIGFRAALAESTDLTREQYEA
                     LHDGHEVELDCPPTNQFVIARTGDTYEAAFQDLGVDYYDYAQ"
     gene            13128..13922
                     /locus_tag="EKH80_RS21210"
                     /old_locus_tag="EKH80_21215"
     CDS             13128..13922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460731.1"
                     /locus_tag="EKH80_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21215"
                     /product="TOBE domain-containing protein"
                     /protein_id="WP_126686798.1"
                     /transl_table=11
                     /translation="MFKLKGILSLQVGDRTLGGADRVALLAKIDETGSITAAARALGMS
                     YKGAWDAIDAMNNLADEPLVMRAAGGKGGGGTHLTERGRRLVETFAALEEVHRRFLEQF
                     DTLADTSAADIKLIRSLMLRTSARNQFSGRVAAIHKGVVNDTVELELPGSNRVVANLTR
                     ESTENLGLKIGSEAIALIKASSVLLALPDSGLHLSARNQFPGTIVQVIEGPVNSDVRLQ
                     LAGGNVMAAVVTTESASQLGLRQGTPVVAVVKASSVMLGTTR"
     misc_feature    complement(13949..13963)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.75"
                     /tool="antismash"
     gene            14121..15437
                     /locus_tag="EKH80_RS21215"
                     /old_locus_tag="EKH80_21220"
     CDS             14121..15437
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_21220"
                     /product="hypothetical protein"
                     /protein_id="WP_126686799.1"
                     /transl_table=11
                     /translation="MLKQRALAAMVGLLAACGVAHADDDIFSNGHVDGDLRLYNFDRLY
                     ASKTVSNASALSAGALINAQTGSFLTGFSIGGSFVTVNSFGTHSNETAKIDTTLAGPNN
                     SIGTFSQAYLQYQHGIFLFRGGYQYLADDPWMGNNDSRIIPSSYNALKLQITPMRGWNL
                     FALREYSWKSRTSSGMFPDNLYYPSKYDGDSMYGNNGSLPLHARSAPGTWEGGTTYVQG
                     GLSAQLRYYDFIHFARTGYAVGSYVFETGSGFNPVIGTQYLVQNGGSDNRFTETGTKLF
                     GVTGTHVKSRVIGGDLGVVIPNGRFDLYYNKVAHEAGAVGGGAVISPYTMNYGTDPLFT
                     TSMIRGLVEAGPGRAWKGKFTYDLLDKKLELTAAYAKYLTDYRGNSHDLYFDVIYHLDG
                     VLKGLTLRNRWELSNGGIGNLNPSNKTFVYNRVMIDYKF"
     gene            15570..15788
                     /locus_tag="EKH80_RS21220"
                     /old_locus_tag="EKH80_21225"
     CDS             15570..15788
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007514121.1"
                     /locus_tag="EKH80_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21225"
                     /product="hypothetical protein"
                     /protein_id="WP_126686800.1"
                     /transl_table=11
                     /translation="MRAILIILGLGLLVGGLWVIFGNGSYTQTETLVQIGSAKLTATHD
                     KAIPSWMGIGGIVLGVLLTAGGLFSKR"
     gene            complement(15852..16550)
                     /locus_tag="EKH80_RS21225"
                     /old_locus_tag="EKH80_21230"
     CDS             complement(15852..16550)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019464573.1"
                     /locus_tag="EKH80_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21230"
                     /product="response regulator"
                     /protein_id="WP_126686801.1"
                     /transl_table=11
                     /translation="MTAANPCVLVIDDETQIRKFLDIGLRAEGYDVLLAANAAEGLALA
                     ATRNPDLVILDIGLPDREGHEVLAELRQWTQVPVLMLSVRDAENEKVKALDTGANDYMT
                     KPFGIQELMARLRALLRNRATGAEALPRYQDERLHIDLGLREVTLDGEPLALTRKEYAV
                     LAMLVRHAGRVVSQQQLLREIWGGTHVHDTHYLRIVLGKLRQKLGDDPTTPRWLKTEPG
                     VGYRFLAGNG"
     gene            complement(16547..19204)
                     /locus_tag="EKH80_RS21230"
                     /old_locus_tag="EKH80_21235"
     CDS             complement(16547..19204)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005988721.1"
                     /locus_tag="EKH80_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_21235"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_126686802.1"
                     /transl_table=11
                     /translation="MTDTSRDARADALLDVVQEESSRRLKIFLGAAPGVGKTYAMLSAA
                     RELKRQGVDVVVGLVETHGRSETAALLEGLEVLPRLALSYQGREFTEFDVDAALARKPD
                     ILLVDELAHRNVPGSRHERRWQDIAELLDAGIEVYTALNVQHLESLNDQVRRITGITVR
                     ETVPDAVLDRARDIVLVDLPPRELIDRLRQGKVYMPETAAAALDAFFSPTNLAALRELA
                     VDTVAGHVDSDLREHMLARGGKMPVRRRVMAAIDGHAQSEYLVRVARRIAERRGAPWTV
                     VFVDTGAALDDARRERIETAMRLARRLGGDATILRGHAIADELLVQADREGVGQIILGR
                     TRERLIARMLGRSLTQQLLRRGAHLELTIIATPAERLRSRKRLRLMPIYGRRDEYIFAS
                     VVTAIAIGLSFIADRYLSVANLALIFLIAVMIVAVRTRMAVAVYTATMCFLGYNFFFAP
                     PRYTLAIANSDDVLAVTLFFAAALICSRLATRLASQVESLRAAHDYSHALLALGQRLSA
                     STDADGIRSVGVTALAHAMRCEVAILSRDVEHRLQVAANSSRTLALTTQDMAAAEWCEQ
                     HVEPAGRYTDTLNAARCWMLPLGSEDHHLGVAALRLEGGVSPNIDRRSLALAMVQDIGQ
                     ALERARLASELEGARVQGETERLRNALLSSVSHDLRSPLASMIGSAGTLSNYGDQLPVN
                     ERKELLEAILGEGQRLDRYIQNLLDMTRLGHGTLKLNRDWTDSAEIVASAITRMRKLFP
                     ELRVDTTLPDETVLLFVHPALIEQALFNILENAARFSPPGDPVRVVVRVAGDRLFIDVI
                     DRGPGIPEEERARIFDMFYSVARGDRAPQGTGLGLAICRGMIGAHGGSVEALPGDGVGT
                     TIRISLPLPTLPSP"
ORIGIN
        1 gtctccttgg gcgttcgcgg ccagagccgc catcattaca acgctcagca tgcgcactcc
       61 gcgaatgggt aaatcagaac aggatgccgg ttatggcatg acgcgaagcg cggcacatgc
      121 tgcagttgca gcaaaggcag gcatttcgcg caggtgatct cgcatggtag gcaagccagc
      181 acgggagcac agcgttctgc atacgtattc atttctctgc tccctcaccc gcttgtgtgg
      241 gagagagcag actcgtcgct caatgcgagt cagccgctcg taacaccaca cgccgcgcct
      301 tctgcgccgc aagtcgcaac aaagtcacgt cgccatagcg atcgtgaccg actgcccaac
      361 cctctccttt cgccgtctgc aaggcttccg cattggcata ggacttgagc gcccccgcgc
      421 tggtggcatt cacgccatgc actttcacca gaaaatactt cagcccgggc ttgtagctgc
      481 cgcgcgctgc ttcgacaccg aattccacgc catcaccacg gcgctgtgta gacagacgtt
      541 gcgagtagaa cacgtcatgc tcgtaggcat aggtgtcgcc gtcatcgtcg tagtaatcga
      601 aatgggtcga gtgctcggct ggaaatacat cgaccgtcag ctcgggcaca ggctgttcgc
      661 ctacgaaatc cgttgccggc tggttgggaa tgatcgcacc ctcgcgaaca aacaatggaa
      721 tgtcatccca ggtctggctg tcgatcgcgt aatgaatggt ctcgccgccc tggtaccgct
      781 tgccggtgaa atagtccgtc cattggcctg ccggaaggta gatcagcttg tccgtctggc
      841 ctttctcaac cactggcgac accagcagtc cggcgccgaa catccaggca tccacgtcgt
      901 cgcgcacctg gctgtcgtcc ggataatcga agctgagcgg ccgcacgatg ccgacgccct
      961 ccgtggtggc agcacgctca taactgtaga tgtacggaat cagcgcatag cgcaggcgca
     1021 tcgcatctgt cgcggccttc tcggcgaccg ggccatacac ccacggctgg cgtttttcgc
     1081 ccagcgtccc gtgcacgcgg aagatcggca cgaaggcagc gaattcgatc cagcgcgcat
     1141 agttctcgtt atccggatgc cccttgaaac cgccgctgtc catgccccac ttcatctcgc
     1201 ccacgtcgat ggcgctgagc atgcgctggc gctgcgccgc catgctgtcg aaaccggtgt
     1261 cgatatcgcc cgaccacagg ccataggcgt aacgctgggc gccgaggtaa aaatcgcggt
     1321 tgatcgacca cactcgggtc ggcgtatagg cgcgctgtcc ttcatacagc gcacgctgca
     1381 tgttgaggaa ttgcgtgttg ctgttggtgt cgtccgcctc gtcgttccac cagccgacga
     1441 taccggtgtc gaaagagtgc ttcagcgcgt cgttgaaaaa ccactcacgc gccgcggccc
     1501 gatcgaagtc cacgtcgcgc accggtttca gagagaagta atccgtgttt tgcgggcggc
     1561 tcgcggccca cagcccgtgc gtctcgacgt agcgcccctc caccgtatcg acgtggatac
     1621 gcggcttcat tatgccggtc atatgcatgc cgagctggtc catcaccgtc ttcagctgac
     1681 cattggaacc gccgggaaac ttgctcttgt tccagcggaa ttcgccgtag ttgtcctctc
     1741 cccaggcctt ccagtcgaag tcgaaggtga agttgtcgat cgggatgtgc cggctacggt
     1801 agccatgcac gatggccagc agttcctgct ggtcgatgcc ccactggctg ttggtgaagc
     1861 ccatcgccca tttcggaaac agcggcgccg gaccgctgag ggtggcgagc gccgcgaaga
     1921 tctgcggtgg ggtgccggca atcacgtcga agctcgcatc cccgcggctg atgccgctga
     1981 cgtcgatacg cccctcagcc agatcgaatt tcgcgccgac ggtgtcgacc agcacgccat
     2041 aaccatgtgt gctccacacg aagggaccgc ccggatagcc ctgttcaccg gccttcgcga
     2101 tttgtacgcc gtggcgcagt agcccgccct tggcaggctc gaaggcatcg tagccgccga
     2161 tgccgtacag cggatcgccg acgtcgtgct gcaggccgat gcgacgatcc accagcgtgg
     2221 ccgggtccgt ccatagcagc acgcgccctt gcgcgtcggc gacactgagg tgtccggcct
     2281 gcttgtccca ggtcgcggtc agctctccgc tagccacgga cgccatgccc gcagtagtgc
     2341 ggacgcgcag gttggcaagc gtatcacgtg aaccatgcgg atccatcacg atgccggggc
     2401 gcgtacttgc gccatgcggc atgccgtgga tctgtacgac gttcggggcg acgaagcgca
     2461 cagtgatctg gtcgttgccc gctttgagtt cgatgccgcg tgcgtcggca tgatcgagct
     2521 ggaagcgtac ttgggtttgg tcggcgcgaa ccgggtggaa catggaagcg atcagcaagc
     2581 cgaaaacggc caaatggcgc agggttgtca tccacccatc ctttcctgtt gcaaagaagc
     2641 tggcatgcac aagccgcccg actataacca tacttcgtcc atgcggggga caaattcctg
     2701 gagatttcat gcctcgtgat agcagcccag acgcgtaggc tgggatgata atcccagctt
     2761 ccgcgcggca tcccggtgct gggattgcca tcccagccta ctgcaggatc accgtggcat
     2821 aaggcggcaa gctcagcttt ccaccggcca ggacggcacc ttcctccgtc tgcagcagca
     2881 cggaggctac gtgtgcatcg ctccccagtt cgaacacgcg cggctcccgc gacaggttgt
     2941 gcactaccag gacgcgcgat tgcgcatcct gcagcatata cgccagcaca tgcgggtcgg
     3001 cagccggcac atcgtgcaat acgccatcgc gcaacgcgct cacctgctgg cgccagccga
     3061 tcagcttgcg atacagattc agcagcgacg cgggatcggc atcctgggct tgaaccgaga
     3121 cagttgcgtc gtcgccgctg ctccaatcct tccagctggc cgtcccctgg cccttgccgt
     3181 tgcgatacca gcgcatcggc tcgcggatat cctcatcggg cttgctgccc tgcatgccca
     3241 gctcttcgcc gtaatagatg aagggatggc ccggcagcgt aagcagcagt tcagcagcta
     3301 ggcgcatatg cagtatgttg ccgtcgagct ggctcatcac gcgttgctgg tcgtgattgg
     3361 agaggaacgg cgcatcgtcg aactccccgt ttgcatgctt gcgaaaagcc gcaaagctgt
     3421 attcgagtcc accaccgatg ccgagattgc gctcctggtc cacgctctcg atcaactgcg
     3481 tggcgagggg gaagtcgaac acggtgttca aggggcccat gtaaggggtc aggtcatccg
     3541 ggttctggcg tgccacttcg ccgaccagcc atacctgcgg tttggctgcc tccagcgcgc
     3601 ggcgatattc ggaccaccag cgcacgttct tctgcagcgc gatcggatcg ctcatatccg
     3661 tgcgcaggtc gtcatagatg tgctgcgcgg catccaggcg gaagccatcg acgccctgct
     3721 gcaaccagaa ccgccctacc tcgatcatgg ccttgcgcac ggccggatgg tcgtagttga
     3781 ggtccggcat ggccgcggtg aacgtgccct cgtagtacgc gccgttcgat gcacgatgcc
     3841 aggcgggacc gccgaccgcg ctgacggcct tcagatccgt accgggcttg gcccacagat
     3901 accagtcgtg gtgcgggtcc ttgggatcca tcgccgcctt gaaccaggga tgctggtcgc
     3961 tggtgtggtt gatcaccatg tccatcacca cctggatgcc gcgcttgtgc gcttcggcca
     4021 gcagcttcct gaagtcctgc aggttgccgt actgcgggtt gatgccttcg taatcggtaa
     4081 tgtcgtagcc gtggtagctc ggcgaggggt tgatcggcat cagccaaata ccgctgacgc
     4141 ccagcgactt gatgtagtcg agcttggcgg tgacgccgtt gagatcaccg atgccgtcgt
     4201 cgttgctgtc gtagaaagcc cggacgaaga tttcgtagta gacgccggat gccgttgcgg
     4261 ccggcttcgc tgccgctttt tcctgcgcca cggcaggcaa ggacagtaac gccagcatcg
     4321 cggccagcaa aacggagcgt agagcggttc tgaacttgga catgggctcg tcctcccgag
     4381 gatggaatgt cgtcgtcacg gcacggccgc gcaacgcggg gaacgacgag ggcgaagcgc
     4441 gtagcgcctg gaaaaaagcc cggctcccca atcgtcaacg gagccgggcc gggggagtgc
     4501 gccggacacc acgagagcgt gtccggcgcc ttgttgcttt tacagcttga agttcacgcc
     4561 caggtagctg gtgcgtccga agtactggat cgtgccggtc tgctgcggat tgccgccgaa
     4621 ataggtcttg gtcggctggt tgctcaagtt gagcatctgg tagaccacgc tcagctgctt
     4681 agtgatgttg tacgaagcct ggaagtcata caccgtttca gccgcaaacg tcaccaactg
     4741 gtgatccact gcaatctgcg tgtccgagag gaacgacgaa cggtagttcg ccgacagacg
     4801 ggccgagaag gtgccgttgt cgtagaacac tgcagcactc gccacgcgct tggacaagcc
     4861 tggcagaccg atgtacgtgg tcggaccggc cagagtggtc gggttgtgca cgttgctgtt
     4921 ggtgagcgcc aggtttgcgt cgaagcccag gcccgaccag atgcccggca ggaagtgcgt
     4981 cttggtgaat gaagcttcca cgccgcgcac gtcgccgccc ttggcgttgt acgaggtctg
     5041 gtactggcca ttggcatacg gctggccagt ggccgggttg gtcggcacct tgatgccggc
     5101 cgcagcaaaa tcgaagttgt tgtaggtgac gttctggatg aacgaattca ccttcttgaa
     5161 gaacacgccg gccgtcaccg caccggtgga atcatcgaag tagtgctcgt aatccacgtc
     5221 gtactgcgtc gcacgcagcg gattcagcaa cgggctggtt ccaccccaca cgttgtactg
     5281 accattggac acccacgaac cggcacccgc gagcatggtg ttgatcggcg gacgcgacag
     5341 caccttcgac gcggcaacgc gcatctgatc ctggtccgtc cagtgataga tcagattgaa
     5401 cgacggcagg tagtcggtat aggtcttgcc ggacttgatt ggcgcatagt cccggctgct
     5461 gttgccgttg ccgtcgacta tcagcacgcc tgcgccattg ccgacttgct gcaggccgta
     5521 gctgtactgt gcctggcgcg acacacgcac gcccacgttg ccggtcagct cgtgaccgaa
     5581 cagctgcgaa tcgatatcgc ccattacgaa cacgtcacgg gtcttttcgt tgaccgaacc
     5641 gctttggatt tccgaccaac tctggtcggt gatgttcttc accgggttgg caacaatccc
     5701 gtgcgcagcg aggatggccg gaccattgag cgtaaggaag caggggaagc cgctgaattt
     5761 gcccttccag cacgtggttt gcgcagcgct ggacgggatg gtcagcggca gctcgccggc
     5821 cacgggcgaa gtgttccact ccgaaccgta gacgtagact tcgcgatcct gcgcgtaggt
     5881 atggttattg agatagaagc ctgcctcgat cgccgagaac accgggttgt tcggcaagtc
     5941 gtattgcact gcggtgcgga aggccttgtc cttgtcgtga tagatgtacg gatagacacc
     6001 gtaacgcgac aaagccatgt cgttgaggtt ggtgtagagg cccggattgc tcaccgacac
     6061 atcgccgata ttgcggccct tgaactggaa ggtcgtcgac tgcgccatca gctgcggact
     6121 ggcagtaccc aggcccgagt aaggatcggc cgtagtgtcg acgttgatct cgttgctggt
     6181 cgcacgcgac aacgagatat cggagtcgat atgccagttg ccatggttcc acttcatgtt
     6241 caggccgccg gagaacacgc tggtgttctt ggtgtagttg tcggccgtcg tctcgttgga
     6301 gaactgggta gtgcccgtgc cagaagcggt accgccgatc accgtaccca gtgagctgag
     6361 cacgggattg gtgatctgcg cgttgttgcc gtagaaattc tgcgagcgga agccgtaacc
     6421 gaacgaactg tcgttgaact tcgagaagaa ggtgtccgcc gtcagctgca ggtccttggt
     6481 cgggcgccaa accacggttc ccaggtaacc gcggcgacgc tcttcaccgc cgttctgctg
     6541 cagttggtag ccttccggca aataggcttg ctgcgcggga ttgttcttgt tcagcgtata
     6601 taggctgccg tccgacgatt cgcccacgaa ctgctcggac acgtgcggct gatacatatc
     6661 cgcaaaaccc aggccgacgc ccagggtgtt atcgaggaac ttgccctggt aagccacgct
     6721 caggcggtag ccgactgcat tggcgcccgg cacgtcgtgg gcctggccgt catagctgcc
     6781 gcgcgtatcg atgttgagcg actggtcctt ggaattttcc agcggattgg ccgtctgcag
     6841 tgcaatggtg cctgccacgc cgcccgtaac cagcgaagcc tgcgaagtct tgtacaccgt
     6901 cgccatgttg atcagctccg acggatactg atcgaactcg atgtagttgg tgccgctggt
     6961 ggagggctgc tcgcggccat ccagcgtggt ctggatgaaa tcgcccgaaa gaccgcggat
     7021 gttgatctgc gaggcctggc cggcgatgcg ctcggcggaa acgccgggca ggtgcgtcag
     7081 cgagtcggcg atggactgat ccggcaggcc gccaatgtcc gcagacgtca ccacgctctg
     7141 gatggtatcg gcgtagcgct ggtagtcgat cgacttctcg acgctgctgc tgaaaccggt
     7201 caccgtcacg gtggacaggc tcttggccag ctcctgctgg cttttcggat tggtggtggc
     7261 ctggcttgtg ctggccgtgt tggactgctg cgccgtgtcg gccgcagtct gagcgccagt
     7321 ttcatccgtc gctgcctgca cgccgaaagc catggtgaga ccggccgaag caagagccat
     7381 caccagcaaa ttacgcttga gtatcacgag tcccctcccc aaaaatcatt tcttgtagtc
     7441 gcctcttgtt ggccgccgac gcaaatttcg cagtacggtc ggcgcccacg cagacggacg
     7501 gaaccggcgg cgtgggtgga tggtagggcg cgcttttcca agcagaccac atcctgcata
     7561 cgtattcata cctacccctt ggcagctgtc atcgcagcgc aacatacgcg ccccgcttgc
     7621 gcgcactact acgctaaaac agcgaaaaag gccggcgtta cgcaattttt acccaaggca
     7681 cgatcgtgac gccttggcga tacccatttt tgccgtgccg ctcatgccgc aaccgcagca
     7741 cgaatgaata cgtatgcaag ccctgcgagc aaccgaaacc tcgcgactaa gctgcaccac
     7801 gccaacaagc tctgcttcct acccggggat cttcgcctgg tacattggga atcttgcatt
     7861 ggcgtcattc ccgcgaaagc gggaatgacg cagacggcgc ggtcgcacgt atccgccgtg
     7921 ggaaggaagc agggccggcg agtttcggct ttactaagga aagcgtttcc aatgaccgat
     7981 gtatcctggt ggcgcggcgc cgtcatctat cagatctatc cacgcagttt tctggatacc
     8041 aacggcgacg gcgtgggtga cctgccgggc atcatccagc ggcttgacta cgtggcgagc
     8101 ctgggcgtgg atgcgatctg ggtcgcgccg ttcttccgtt cgccgatggc cgatttcggc
     8161 tacgacatcg ccgattaccg cgatgtcgac ccactgttcg gcacgctgga ggatttcgat
     8221 tccctgctcg ccaaggcgca tggcctgggc ttgaaggtga tgatcgacca ggtactgagc
     8281 catacctccg accagcatgc ctggttcaag gaaagccgcg aaagccttgg caacgcgaaa
     8341 gccgactggt acgtctgggc ggatgcaaaa cctgatggca gcccacccaa caactggttg
     8401 tcgatcttcg gcggttcggc ctggcaatgg gaaccgcggc gcggccagta ctacctgcac
     8461 aactttctcg cttcgcagcc ggacctcaat ttccaccatc cggaggtgcg caccgcggtg
     8521 ctcgacaatg tgcgcttctg gctggacaag ggcgtggatg gcttgcgcct ggatgcgatc
     8581 aacttctgct tccacgaccg gcagctgcgc gacaacccgc ccaagccgaa ggaaaggcgc
     8641 gtgggccgcg gcttcagccc ggacaatccg tatgccttcc agtatcacct gtacaacaac
     8701 acccagccgg aaaatctcga tttcctgggt gacttgcgcg ccctgctcga ccgctatccc
     8761 agcgcagtga cgctcggcga gatctcctcg gaggactcgc tggcgacgat ggccgaatac
     8821 acccgcggcc atcgcctgca catgggctac agcttcgaat tgctcagcag cgacttcagc
     8881 gccgcataca ttcgccgaac cgtggcgcaa ctggaagcgc aggtaagcga aggctggccg
     8941 tgctgggcca tttccaacca cgatgtggaa cgcgtgctca cgcgttgggg caacggcaac
     9001 acctcgccac gcctggccaa tctgctcact gccatgctgt gctcgctgcg cggttcggta
     9061 tgcgtgtacc agggcgaaga gcttggcctg accgaagccg aggtaccgtt cgaggccctg
     9121 cgagacccct acggcatcac cttctggccg aacttcaagg gccgcgacgg ctgccgtacg
     9181 ccgatgccct ggaatgaggg accttttgcg ggtttcagcc cggtggcgcc atggctgccg
     9241 atcgacgaag cccacaaggc gttggccgtg acgcatcagg aagccaacgc gaactccgtg
     9301 ctgcatggct tccgtcgctt catgcattgg cgcgccgcgc aatcggccct gcggcagggc
     9361 gacattcgtt tcctcgatgt gcccgagccg atactggctt tcgtgcgcca cgatggctcc
     9421 gggcaggtgt tggcggcatt caatctcggc aagctgccac agacggtggc gctggccgga
     9481 ttcgatgcag ccacgccgct ggaagggcac ggcttgcagc aaggcacact acagagcgga
     9541 caactggagc tccctggaca tggggtcctg ttcgcccgga tcgcataaca gcgaccacgt
     9601 agcctgggag gacaatcgta ggctgggtcg gcaaacccag cattgccatg cacgcaaccg
     9661 cacgatgctg ggattgtcat ccccgcctac gacccgtgaa tcaacccgtc ccgcttattt
     9721 ccatataaat caacatactt agacatccaa attcacgtca tcatcacatt cccaagccta
     9781 ggatttcaca cgcagtagtc aaatacagga accggggcca catcctttgg tagccaggcg
     9841 gcgccgcccc ttcggcgccc catgaaagcg tgatggtgac aaccgctgcc cgggccggct
     9901 gcttcccgcc cgacagtcca caaaatcggc ggcggccgaa tcttccttgc agcactttac
     9961 cggtcatccc gttgtgccgt tcctcacgga gagagccgcc atgcaccgct ttgagagtct
    10021 gcctgccaat tacgcaccgt tcgcagcgcc gctggagtac gaggcaccga atggattgcg
    10081 cctgccgaat ctgcactatc cctgggcgag cgcgtgctcc ccgcatgcgc cctttgtgga
    10141 agcgcgcatg cagcaatggc tggtacagca cggcctcatt cccaacgagc attaccgggc
    10201 acgcatcgca caggccaaat tcggctggct cgccgcgcgc tgccacccct atgcgtcgct
    10261 tgagcggctg cagaccattg cctatttcta tgcctggtat ttcctagtcg acgactggtt
    10321 cgtcggccgc accgaaaagg tatcggccta caccatttcc aatcttgagg cggtgatcga
    10381 tgtactcgac atcggccgca tcggcaacga gccggtgtac ggcgaaaccg cctgggtgga
    10441 tctgtgccgg cagctgcggc tgagcatgtc cgacgcccag ttcgagcgtt tcgcgcatgc
    10501 catgcatctg tgggtgggaa tggccggcct gcgcatgctg gaacattcgc atgcgcgcac
    10561 agctcccgcg catcggcatg aagccatcct gcgccatgcc ggaggccttt atccctgtct
    10621 gtatctgatc gatttcgcca acggcctgcc gctagcgcag gaggagcacg accaggtcga
    10681 tgtgcagcaa ttgcgccggc ataccaatcg cgtcgtgtgc tggagcagcg atgtgcaaca
    10741 tctgggtctg gacgtccacc agtcggcccc gcatcggaac acggtggcgc tgtacgccag
    10801 tcaaggctat tcgctacagc gcagcttgga ccgcgtgggc gaacgcatcc gtacggagat
    10861 cgacgccttc atggtcgcgg ccagtgcggt gagggaagac gccggccccg cgttatccag
    10921 ctacatccgc ggactgaagc attggatgag cgggtaccgg gactggctgg cctcgcagca
    10981 tggaatgcgg gcctttactg agacagaagc cgcgatcaag gcctggtaag cctcaggacc
    11041 ctctgatcta ttcctacgca tccgtcacca cacgctcggg ggcctcactg tatgcgcgtc
    11101 aggcggagcg taggctggga tggcaatccc agcattgcca tgcttgcagc cgcgcgaggc
    11161 tgggattgcc atcccagcct gcgggccttc tggacgtcat gccgggcacg taggaataga
    11221 ccagagggtc cttggcgaaa catcgttcac cacgctaccc caaaagcccc cggcgattgc
    11281 gaatgtaacc aaaagtcgac tagctgaaag ctaacgtggt taaaatctcg tggttcggcc
    11341 gggcgctcgc atccccccgc ccgggcggcc gcgtccggct tgaaggacgt ccgccctgcg
    11401 acgcgtctcc atgtccccgc agcttgcgcg ctcccaagcg cgcacggcgg ggtcattgtg
    11461 gccggcgttg ctccgacacc atcgaggaac aagcttttga acacagcgaa cgacacggca
    11521 gcacgacgca acccaggcgt aagcggcatg agcctgtatg taccccgccc acgcgtgtcc
    11581 ctgcgcgact ggtgcgaatg gaccggcaac tcctgggaca aggtccaggc cgtggtaggc
    11641 cgcagtttcc gccagccggc gccgtatgaa gacgcctaca ccatggctgc caccgccgta
    11701 ctgcggctga tctgccagta caacatcgac ccgcgcaacg tcggccagct tgcgctcggc
    11761 actgaaagca gcaaggacaa ctcagccggc gcggtgatcg tgcgtggcat ggtggatcgc
    11821 gagctggaac gcctggggct gccgcgcctt tcacgccagt tggaagtacc ggagttcaag
    11881 cacgcctgtc tgggcggcgt ctatgccctg aagagcgcac tacgctacgt gggattcgat
    11941 gccaacggcc gccaggcgat cgtcgtgtgc agcgatatcg ccgcctacga gcgcgggtcc
    12001 agtggtgagc agacgcaggg cgccggcgca gtggcgatgc tggtggaggc acagcccaag
    12061 ctgttcgagg tggatctggc ccatgccggc agcgcctccg attaccgcgg cccggacttc
    12121 cgcaagccgt tccttcgcca cttccatcac gaatacggcc agcgtcaccg ccgcctgcac
    12181 gatttcccga tcttcagcgg caaatactcc accttcgcct atctggacga agtgggccag
    12241 gccaccgatg cgatgatcca gcggctgggc gtgtcggatc tggacctcct cgaaagcgcg
    12301 ggcgggctgt tcttccatcg cccgtaccac atgatgccgt tgcaggccct ggccttcatc
    12361 tacgcccgcg cccttgcacg cgcaccgcag ccccatgccg gtttccaggc cctgtgcgag
    12421 ctctctggcg tctcgccgga cggcgtagtg gccgaatgcc gcaacacgcc ggacctgtat
    12481 ggcgagtttg tgcgccaggg cgcgcatgcc gacgccgccc aggatgcgca cccgctcacc
    12541 accaagctgt ccggcgtggt gcgcaagagc ccggcgttcc agcagttgct ggccacgcgc
    12601 gtcaaccagg gcaccgattg ggccatggag ctgggcaatc tctataccgc cgcgctgccg
    12661 gcgtggatcg ccgccggctt cgagcaggcg ctggaaagca acgtcgaatg gacggatgcc
    12721 aggctctatg cgatcggcta cggcagcggc gacgcctccg aagccattcc gctgcgcgtg
    12781 gtgccgggct ggcgcgaagc ggcggcgaag atcggctttc gcgcggcctt ggccgagtcc
    12841 accgacctga cccgcgagca gtacgaagcg ttgcatgatg gccacgaggt ggaactcgac
    12901 tgccctccca ccaaccagtt cgtgatcgcg cgcactggcg atacctacga agcggcgttc
    12961 caggatctcg gcgtggatta ctacgactac gcgcagtgat ctttccgctg ccggactccc
    13021 gcaggctggg atgaattccc agcttgcgta ccgatggcga tgctgggatt tcatcctggc
    13081 ctacacggct aaaatggctc ccgtcggtcc atcaggcggg cgggggaatg ttcaagctca
    13141 aaggcatact gtcgctgcag gtgggcgacc ggacgctggg cggcgccgat cgcgtcgccc
    13201 tgctggcgaa gatcgatgaa accggctcca tcaccgccgc cgcgcgcgct ctcgggatga
    13261 gctataaggg cgcatgggat gcgatcgacg ccatgaacaa tctggcagac gagcccctgg
    13321 tgatgcgcgc ggccggtggc aagggcggcg gcggcacgca cctcaccgaa cgcggccggc
    13381 ggttggtcga aaccttcgcg gcgctggaag aagtgcatcg ccgctttctc gaacagttcg
    13441 acacgctggc cgatacctct gccgccgaca tcaagctgat caggagcctt atgttgcgca
    13501 ccagtgcacg caatcagttt tcggggcgcg tggcggcgat ccacaagggc gtggtcaacg
    13561 atacggtgga actggagttg cccggcagca atcgcgtggt cgccaatctc acccgcgaga
    13621 gcacggagaa tctgggcctg aagatcggta gcgaagcgat cgccctgatc aaggcttcct
    13681 cggtgctact ggccctgccg gactcgggtc tgcatctgtc ggcacgcaat caatttccgg
    13741 gcacgatcgt ccaggtcatc gaggggccgg tcaactcgga tgtgcgcctg cagcttgccg
    13801 gtggcaacgt gatggcggcg gtcgtgacca ccgaaagcgc gtcccagctg ggccttcggc
    13861 aagggactcc ggtagtggcc gtcgtgaaag cctcgagcgt gatgctcggg accacccgct
    13921 gagcaacccc gttcgaaacc atcctaagga tggtctgaaa aaaatccgtc ctggattttt
    13981 tcagacgcgc atccttgcac cgcggaagct ctgaataaat cagagccgcc ctaagcggca
    14041 tccggaaacc gtcatatact cgtttatata gcgccaggcc gggctacctg gcgatcggcc
    14101 acttgcgatg gggaatgggc atgttgaagc aacgggcgct tgccgccatg gttggactac
    14161 ttgcggcctg cggcgtagcg cacgcggacg acgacatctt cagtaacggc catgtggacg
    14221 gcgatctgcg cctctacaac ttcgaccgcc tctacgccag caaaaccgta tcgaacgcca
    14281 gcgccctctc cgccggcgca ttgatcaacg cgcaaaccgg cagcttcctc accggcttca
    14341 gcatcggcgg ttcgtttgta acggtcaatt cgttcggcac gcattcgaac gaaacggcaa
    14401 agatcgatac cacgttggcc ggcccgaaca actcgatcgg cactttcagc caggcctatc
    14461 tgcaatacca gcacggcatc ttcctgtttc gcggcggcta tcaatacctc gccgacgacc
    14521 cgtggatggg taacaatgat tcgcgcatca tcccctcctc gtacaacgcg ctgaagctgc
    14581 agatcacgcc catgcgtggc tggaacctgt tcgccttgcg cgaatacagt tggaagagcc
    14641 gcacctcctc cggcatgttc ccggacaacc tgtactaccc gtccaaatac gacggcgatt
    14701 cgatgtacgg caacaacggt tcgctgccgc tgcacgcgcg ttccgcaccg ggtacctggg
    14761 aaggcggcac tacttacgtc caaggcgggc tgagcgcgca gttgcgctat tacgacttca
    14821 tacatttcgc ccgcaccggg tacgcggtgg gcagttacgt gttcgagacc ggttcgggct
    14881 tcaatcccgt catcggcact cagtacctgg tgcagaacgg cggatcggac aaccgcttca
    14941 ccgaaaccgg caccaagctc ttcggcgtga cgggaacgca cgtgaaaagc cgtgtcatcg
    15001 gcggcgacct cggcgtagtg attcccaacg gccgcttcga cctgtactac aacaaggtag
    15061 cacacgaggc cggtgcggtg ggcggcggcg cggtgatttc gccatacacc atgaactacg
    15121 gcaccgaccc gctgttcacc acttcgatga tccgcggcct ggtcgaagcc ggcccgggcc
    15181 gcgcgtggaa aggcaagttc acctacgacc tgctggacaa gaaactggaa cttacggccg
    15241 cctacgcgaa atacctgacg gattaccgag gcaacagcca cgacctgtat ttcgacgtga
    15301 tctatcacct ggacggcgtc ctcaagggct tgaccctgcg caaccgctgg gagctctcca
    15361 acggcggcat cggcaacctc aacccaagca acaagacctt cgtctacaac cgcgtgatga
    15421 tcgactacaa attttgagcg cggggcgtag gctgggatgg tcattcctgc ctgcaagttt
    15481 taagggcgcg tgaagcggcg gcggaggccg tcttcctttt gtacgacgcc ggcgcctatg
    15541 atccctgcaa ctttttcgcg gagcgaagca tgcgtgccat cctgatcatc ctggggctcg
    15601 ggctgctggt cggcggcctg tgggtcatct tcggcaacgg cagctacacc caaaccgaaa
    15661 ccttggtcca gatcggctcg gccaagctca ccgccacgca cgacaaggcg attccgtcgt
    15721 ggatgggtat cggcgggatc gtgctgggtg tgctgctgac ggcaggcggc ttgttttcca
    15781 agcgctgagc gcatgcgtcg ggatgacgac ctggccagag caaggcatac gcaaaatcgc
    15841 gagaatggcc ctcacccatt cccagccaga aagcggtacc ccactcccgg ctccgtcttc
    15901 agccaccgcg gcgtcgtcgg atcatccccc agcttctgcc gtaatttgcc gagcacgatg
    15961 cgcaggtagt gcgtgtcatg cacatgcgtg ccaccccaga tctcgcgcaa cagctgctgt
    16021 tggctcacta cgcgaccggc gtgacgcacc aacatcgcca gtaccgcgta ctccttgcgc
    16081 gtcaacgcaa gcggctcacc gtcaagcgtt acttcgcgca agccgaggtc gatatgcaga
    16141 cgctcgtcct gatagcgcgg caaggcttca gcgccggtgg cacggttgcg cagcaaggcg
    16201 cgcaggcgtg ccatcagctc ctgtatgcca aatggcttgg tcatgtagtc gttcgcgccc
    16261 gtgtccagcg ccttgacctt ttcgttctcg gcatcgcgga ccgaaagcat cagcaccggc
    16321 acctgcgtcc attggcgcaa ttcggccagc acttcatggc cttcgcggtc gggcaggccg
    16381 atatccagga tcaccaggtc aggattgcgc gtggcggcaa gggccaagcc ttcggcggca
    16441 ttggccgcca gcagcacgtc gtaaccctcg gcgcgcaagc cgatgtcgag aaatttgcgg
    16501 atctgcgttt cgtcatcgat gaccaggacg caggggttgg cggctgtcat ggcgatggaa
    16561 gagtgggcag tggaagacta atgcgaatgg tcgtgccaac gccatcgcca ggcaaggctt
    16621 ccacgctgcc gccgtgcgcc ccgatcatgc cgcggcagat cgccagcccc aaaccggtgc
    16681 cctgcggtgc gcgatcgccg cgcgccacgg aatagaacat gtcgaagatg cgcgcacgtt
    16741 cttcctcggg aatgccgggg ccgcggtcga tcacatcgat gaacagccga tcccccgcca
    16801 cgcgcacgac cacgcgtacc ggatcgccgg gtggcgaaaa gcgggcggca ttctccagga
    16861 tattgaacag cgcctgttcg atcagcgccg ggtgtacgaa caacagcaca gtttcatcag
    16921 gcagcgtagt gtccacccgc agctcgggaa acagcttgcg catgcgggtg atggccgagg
    16981 cgacgatttc ggcggagtcg gtccagtcgc gattgagctt gagcgtgccg tgacccaggc
    17041 gtgtcatgtc cagcagattc tggatatagc ggtccagccg ctggccttcg cccagaatcg
    17101 cctcgagcag ttccttgcgt tcattcaccg gcaactgatc cccataattg gagagtgtgc
    17161 cggccgagcc gatcatcgat gccagcggcg aacgcaaatc gtgcgatacg gaggagagca
    17221 gcgcattgcg caagcgttcg gtttcgcctt gcacgcgtgc gccttccaac tcggaagcga
    17281 gccgcgcacg ctccagcgcc tggccgatat cctgcaccat cgccaacgcg aggctgcgcc
    17341 ggtcgatatt cggcgaaacg ccgccctcca agcgcagcgc cgctacgcca agatgatggt
    17401 cctcgctgcc cagcggcagc atccagcagc gggcggcatt gagcgtatcg gtgtagcgtc
    17461 cggccggttc gacatgctgt tcgcaccact cggccgcggc catgtcttgc gtagtcaggg
    17521 cgagcgtacg cgaactgttg gccgcgacct gcaagcggtg ctccacgtca cgcgacagga
    17581 tggccacttc gcagcgcatg gcgtgcgcca gggccgtgac gcccacgcta cggataccgt
    17641 ccgcgtccgt gctggcggag aggcgttgtc caagcgccaa tagcgcgtgc gaataatcgt
    17701 gtgcggcgcg cagcgattcc acctggctgg ccaggcgcgt ggccaggcgg ctacagatca
    17761 atgccgccgc gaaaaacagc gtcaccgcca gcacatcatc cgaattggcg atggccaggg
    17821 tgtagcgtgg cggcgcgaaa aagaagttgt agcccagaaa acacatcgtc gcggtgtaaa
    17881 ccgccactgc catgcgtgtg cgcaccgcca cgatcatcac ggcgatgaga aagatcaggg
    17941 caagattggc caccgacaga tagcggtcgg cgataaagga caagccgatc gcgatggcgg
    18001 tgacgacgct ggcgaatatg tattcgtcgc gacgcccgta gatcggcatc agccgcaggc
    18061 gtttgcgtga acgcaagcgc tcggccgggg tggcaatgat ggtgagttcc aggtgagcgc
    18121 cgcgacgaag caattgctgc gtcaacgaac ggccgagcat gcgtgcgatc agtcgctcgc
    18181 gcgtccgccc taggatgatc tggccgacgc cttcacggtc ggcctgcacg agcaattcgt
    18241 cggcaatggc gtggccgcgc aagatagtgg catcgccgcc caggcgccgt gccaggcgca
    18301 tcgccgtttc gatgcgctcg cggcgcgcgt cgtccagggc tgcaccggtg tccacgaata
    18361 ccacggtcca cggcgcaccg cggcgctcgg cgatgcgacg cgcgacgcgc accaggtatt
    18421 cgctctgcgc gtggccgtcg atggcggcca tcacccgtcg ccgcaccggc atcttgccac
    18481 cgcgcgccaa catgtgttca cgcaggtcgc tgtcgacgtg accggcgacg gtgtccaccg
    18541 ccagttcacg cagggccgcc aggttggtgg gcgagaagaa cgcgtccagc gcggcggcag
    18601 cggtttcggg catgtagacc ttgccttgcc gcaggcggtc gatcagctcg cgcggcggca
    18661 ggtccaccag cacgatgtcg cgcgcgcgat caagcacggc gtccggtacc gtttcgcgca
    18721 cggtgatgcc ggtgatgcgg cgcacctggt cgttgaggct ttccaggtgc tgcacgttga
    18781 gcgcggtgta gacttcgatg ccggcatcga gcagttcggc gatgtcctgc cagcggcgct
    18841 cgtgccggct gccaggcaca ttgcggtgcg cgagttcgtc gaccagcagg atgtccggtt
    18901 tgcgcgccag cgccgcgtcc acgtcgaact cggtgaattc gcgcccttga tagctcaggg
    18961 cgagccgcgg cagaacctcc aacccttcca gcagcgccgc cgtttcgcta cggccgtgcg
    19021 tttccaccag gccgaccacg acatccacgc cctgccgctt caattcgcgc gcggcagaca
    19081 gcatggcgta ggttttgccc acacccggcg cggcacccag gaagatcttc agtcggcggc
    19141 tgctttcttc ctgcacgaca tcgagcaggg catcggcgcg ggcgtcacgg gaggtgtcgg
    19201 tcatgaggga atcataagcg tgtgttcgcg ttcttgccgc tatctactcc ctcccctgca
    19261 ttgcacttga ttagcgtcga gtctcagtag gtgagcagag gtagggcgag catggcggca
    19321 tccctcaagc ggaggtgccg ccatgccgat gaaccgcg
//
