LOCUS       NZ_RYYV01000019        21992 bp    DNA     linear   CON 06-MAY-2024
DEFINITION  Dyella choica strain 4 M-K27 scaffold19, whole genome shotgun
            sequence.
ACCESSION   NZ_RYYV01000019
VERSION     NZ_RYYV01000019.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dyella choica
  ORGANISM  Dyella choica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Rhodanobacteraceae; Dyella.
REFERENCE   1  (bases 1 to 84269)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Dyella dinghuensis sp. nov. DHOA06 and Dyella choica sp. nov.
            4M-K27, isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 84269)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135, Xinggang West Road, Guangzhou, Guangdong
            510275, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina Hiseq 4000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003977665.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 01:53:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,733
            CDSs (total)                      :: 4,678
            Genes (coding)                    :: 4,648
            CDSs (with protein)               :: 4,648
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 9 of 30
            Pseudo Genes (incomplete)         :: 25 of 30
            Pseudo Genes (internal stop)      :: 5 of 30
            Pseudo Genes (multiple problems)  :: 9 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:37:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 38886
            Orig. end                         :: 60878
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYYV01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21992
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21992
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21992
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11992](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11992)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(784..804)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 27.09"
                     /tool="antismash"
     misc_feature    complement(917..932)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            complement(1050..2804)
                     /locus_tag="EKH80_RS19240"
                     /old_locus_tag="EKH80_19245"
     CDS             complement(1050..2804)
                     /GO_function="GO:0009975 - cyclase activity [Evidence IEA]"
                     /GO_process="GO:0009966 - regulation of signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00254.1"
                     /locus_tag="EKH80_RS19240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19245"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_158628890.1"
                     /transl_table=11
                     /translation="MAAVHASNDITQLLVQADSIKTTDNPGFVRLLDGLEGRTTEMSEA
                     QKWRLRFLEGWQADYSGREDKAKSLLEAVVKQAPDNELRTRATAALINVLGVQHHYEEA
                     FEYLDRALENLPPVADQGARFPILGEASQLLSEVGQYDLAAGYAKQIIADYPKGNIGCI
                     GHMLQLHAEIRGGQKRIAGELFQKGIKRCLDVGDKLAADTIRRDIAVLDLQQDRTDDAL
                     AILQATNDEVKGLNYQALTAEYNVLLAQAYWKKGNVALAQKYAMATVDVASRSNLTEPL
                     IKAYQLLYQVEQQYGNLREALAYHEKYVAADKEHLDDIREKALSYQIVKQQVETKKIEL
                     NELNKQNQILQLQQALNGKAVVTSRLYITLLLTVLASIAFWLYRLKRSQLRFMRLARRD
                     GLTGIFNRQHFVEEAEQTLRYAAKSLRGACLVLIDLDHFKDINDTHGHVVGDTALKRAV
                     SVCQQHLHSCDVFGRIGGEEFGILLPESTLIQALERAEKIRLALQATTNDTQDHVALTA
                     SFGIASTAHYGYDLRRLLLAADSALYRAKRDGRNRVVISMDEHTPRAPTYTGNGKLADK
                     HPYANSSE"
     misc_feature    complement(2875..2886)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     gene            complement(2883..3173)
                     /locus_tag="EKH80_RS19245"
                     /old_locus_tag="EKH80_19250"
     CDS             complement(2883..3173)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS19245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_19250"
                     /product="hypothetical protein"
                     /protein_id="WP_126686420.1"
                     /transl_table=11
                     /translation="MSNVMRFLETIGGEARWGDITKDAMELALGNASIEGPLRSAILNN
                     DAAQLLALLQGKTPVGYVMPGEEEEEEEEEDDEPGERDTRQPSSSSTTSAQ"
     gene            complement(3340..4137)
                     /locus_tag="EKH80_RS19250"
                     /old_locus_tag="EKH80_19255"
     CDS             complement(3340..4137)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460251.1"
                     /locus_tag="EKH80_RS19250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19255"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_196240410.1"
                     /sec_met_domain="TP_methylase (E-value: 2.5e-24, bitscore:
                     78.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVLDSIQPKGSLACVGIGMTLGSHLSRRAHAYIEQADVVFTLVS
                     DGIVELWLQGMNEDVRSLQPYYQEGKSRMKTYRQMVNAIMAEVSAGRRVCGVFYGHPGV
                     FAWVPHKAIRTARSKGYHAHMEPGISSEDCLYADLGIDPGARGCQHYEASQFMLYRRCI
                     DPSAWLILWQVGVAGDKTLMRFSTGEAHRQVLVDVLARHYTLDHQVVIYRAATLPFQSP
                     RRELLALGALPLAEFGMADTLAIPPARPLEADHEIRARLEALA"
     misc_feature    complement(4115..4133)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.96"
                     /tool="antismash"
     gene            4215..4850
                     /locus_tag="EKH80_RS19255"
                     /old_locus_tag="EKH80_19260"
     CDS             4215..4850
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022019.4"
                     /locus_tag="EKH80_RS19255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19260"
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="WP_158628891.1"
                     /transl_table=11
                     /translation="MSERATPDDWDLPDPERSGRTFVYVLPSQGEDLTKLGFTQDPVQR
                     FRSFHPRFFALFDLESGLLVETGRLRDARRLERLLIERWPDHRAPAPLLVAEAAGGHTE
                     WFRGIGGEVDAFVRRTAERYGYALHAPLSAWLRARFSERADQLYEWSQRLLEMIEWQTA
                     NLPPEERNLRYAKALRDNLDACHAVGMNLHALLPARVMAWYASARGNG"
     gene            4938..5678
                     /locus_tag="EKH80_RS19260"
                     /old_locus_tag="EKH80_19265"
     CDS             4938..5678
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_N_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015448137.1"
                     /locus_tag="EKH80_RS19260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19265"
                     /product="glutathione S-transferase family protein"
                     /protein_id="WP_126686422.1"
                     /sec_met_domain="GST_N_3 (E-value: 4.7e-09, bitscore: 29.0,
                     seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="GST_C (E-value: 9.3e-07, bitscore: 21.4,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSITLYATRPGFGMPETSPFVIKTEVQLKMADLSYGRESTIP
                     PLAPKGKVPYLLDDGEVVCDSTFIRAHLERKYGVDLDEGLDAHQRAQSWAIERMLEDHL
                     YFAMVWFRWIVPENFAKGPAQFANGAPEEQREALRREMQSRKDGDLRSHGIGRHSAGEI
                     AALGVRSIDALAALLGDKPYLMGERMTAVDATALGVLASILTSFFDTPLRDAVASRPNL
                     VAYVSKLMQRYYPEHAWEPAAEAV"
     gene            5880..6197
                     /locus_tag="EKH80_RS19265"
                     /old_locus_tag="EKH80_19270"
     CDS             5880..6197
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS19265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_19270"
                     /product="hypothetical protein"
                     /protein_id="WP_126686423.1"
                     /transl_table=11
                     /translation="MEVSFNNWGEAVAFLSERTDIALEGLMALSAQQMVDQQVIAALLA
                     SHTHLRAAADAWRQMASATLPITHVRSLQNDQPESVRVAYSERMAYWEELFRKAIPQKS
                     E"
     misc_feature    5881..5895
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.53"
                     /tool="antismash"
     gene            6297..7127
                     /locus_tag="EKH80_RS19270"
                     /old_locus_tag="EKH80_19275"
     CDS             6297..7127
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019466176.1"
                     /locus_tag="EKH80_RS19270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19275"
                     /product="creatininase family protein"
                     /protein_id="WP_126686424.1"
                     /transl_table=11
                     /translation="MTKRLAFRRVIASVVFVIAVIAAQGASAQTTSTVQLQNLTWTELR
                     EQIHAGKTTLIIPIGGTEQSGPYIAVGKHNVRAAYLADRIAQKLGNALVAPVVAYVPEG
                     GYAPPTSHMRFPGTITVPDDVFEKMLEAAANSFAVHGFRNIVFLGDHGGYQKDLKQVVA
                     RLNKAWAGANARAILPAAYYEASSDGYAQLLRQRGFRDDEIGTHAGLADTSLQLAVAPQ
                     MVRTNQLRNAPKPGAADGVYGGDPRRSTAELGQIGVDAIVSRTVDAIRQETAGH"
     gene            7183..8346
                     /locus_tag="EKH80_RS19275"
                     /old_locus_tag="EKH80_19280"
     CDS             7183..8346
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019466177.1"
                     /locus_tag="EKH80_RS19275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19280"
                     /product="YncE family protein"
                     /protein_id="WP_230473831.1"
                     /transl_table=11
                     /translation="MKFDRFGRLALRAGAVLAGLCVTAAAAAQTVQTVPGMPPVTNPHD
                     MYSNAGFNMFSPAVKGALPRIYVPNLRSNDVYVIDPATFKVVDRFAVGRSPQHVVPAWD
                     LKTLWVTNNAEGRNDGSLTPIDPMTGKPGKADPVDDPYNMYFTPDGKEAIVVAEAFARL
                     DFRDPHTMALKSRLPAPECKGINHADFSIDGKYAIFTCEFGGKLVKIDMVNRKVLGYLQ
                     LNKRGMPQDIRVSPDGKVFYVADMMADGVYLIDGDSFKQVGFVKTGIGTHGLYPSRDGT
                     KLYVANRGSNKVHGPRNGPGSVSVIDFATRSVVANWPIPGGGSPDMGNVTADGKWLWLS
                     GRFDDVVYAFDTATGKVQIIKVGMEPHGLAVWPQPGRFSLGHTGIMR"
     gene            complement(8405..9613)
                     /gene="fabV"
                     /locus_tag="EKH80_RS19280"
                     /old_locus_tag="EKH80_19285"
     CDS             complement(8405..9613)
                     /EC_number="1.3.1.9"
                     /GO_function="GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fabV"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014506054.1"
                     /locus_tag="EKH80_RS19280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19285"
                     /product="enoyl-ACP reductase FabV"
                     /protein_id="WP_126686426.1"
                     /transl_table=11
                     /translation="MVIHPKVRGFICVTAHPLGCEKNVLEQIGITKAKGACGSGPKRVL
                     VIGASTGYGLASRITAAFGCGAATLGVFFEKPSSDSKPGTAGWYNSAAFDKLAKQAGLY
                     SRSINGDAFSHETRARAIELIKNDMGGPVDLVIYSLASPVRKLPDTGELVRSTLKTIGQ
                     PFTASSVDTNKDSVVQVTVEPANEQEIKDTIAVMGGEDWALWIDALSKAGVLADNATTV
                     AYSYVGTEITWPIYWHGTIGQAKQHLDNTAQELNRHYAAQHLRAYVGVMKSVVTQASSA
                     IPVIPLYVSMVFRIMKEKGLHEGTIEQANRLFHDFLYRQDGALPSTDEEGRLRLDDWEL
                     REDVQQACKTLWPQVSTENLWETTDYAGYKHEFLRLFGFDRKDVDYNADVNPDASFDVV
                     QLS"
     misc_feature    complement(9795..9810)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.36"
                     /tool="antismash"
     gene            9823..9999
                     /locus_tag="EKH80_RS23870"
     CDS             9823..9999
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS23870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158628892.1"
                     /transl_table=11
                     /translation="MTTLKPSNAPHEAPGREAGEPYDPHKRRGPPQRLEDTNASGDALN
                     DTGEDNQRQKEEE"
     gene            complement(10001..11992)
                     /locus_tag="EKH80_RS19285"
                     /old_locus_tag="EKH80_19290"
     CDS             complement(10001..11992)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024306.4"
                     /locus_tag="EKH80_RS19285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19290"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_126686427.1"
                     /sec_met_domain="indsynth (E-value: 1.1e-31, bitscore:
                     101.8, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSYSPSHTVPSREQALHALYEAAELEHCLMCTYLYAAFSLKSSA
                     EEGVTADQLEAITRWKRSILQVAIEEMGHLMSVWNITVALGGAPRLGRSNFPLDPGYLP
                     AGVVVKLAPFNRATLQHFIYLERPAGSTEPDGEGFEPERHFLRGANGPRLTPMGINYET
                     VGEFYQTLGNGLRGMVQKYGEAGAMCGDPALQLSKAEVSLPGANKVICLKTALAAFESI
                     ITQGEGAQENTENSHYQRFAAIRAEYEALLAADPSFKPAFPAATNPVLRRPPRPEGRVW
                     LENEDAIATVDLANAAYGLMQRLLAYSYAVPAPDPDKCLSLDLGIGLMRALAPLAERAA
                     RLPAGPSNPDCHAGVTFITLRDTSPLPPGPSARRFFLERFEQLTEAAERLSASNDPRTI
                     AAAAVFKHLSQQAEQGFDLARPAPSAAVAASTPALAAAPAPAAPASTVVEDGIEQVEGE
                     KLTLRFEAKRCIHARFCVTGAPKVFLANVQGPWIHPDAMDVERLVDIAHACPSGAIQYQ
                     RRDGRPDESAPPVNLAAVREAGPYAFRGDLRLAGKPAGFRATLCRCGASKNKPFCDGSH
                     HDVGFNASGEPPTGTSNEELTARDGPLQIDPQMNGPLRVRGNLEIISGTGRMVARVTGT
                     YLCRCGHSQNKPFCDGSHAKVGFTADGA"
     gene            complement(12134..12895)
                     /locus_tag="EKH80_RS19290"
                     /old_locus_tag="EKH80_19295"
     CDS             complement(12134..12895)
                     /NRPS_PKS="Domain: PKS_KR (7-177). E-value: 1.1e-12. Score:
                     40.2. Matches aSDomain:
                     nrpspksdomains_EKH80_RS19290_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018971402.1"
                     /locus_tag="EKH80_RS19290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19295"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_126686428.1"
                     /sec_met_domain="adh_short (E-value: 3.5e-34, bitscore:
                     110.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.1e-31, bitscore:
                     102.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTPIALITGGSRGLGKNMVLRLAEHGTDVVLTYRSNQAEAEAV
                     VASVTKLGRRAVALPLDVGKTSSFAAFAGQLRTVLQEQWQRDRFDYLVNNAGIGIHASF
                     AETTEAQFDELVNVHFKGAFFLTQALLPLIADGGRVLNVSSGLARFALPGYAAYASMKG
                     AIEVLTRYLAKELGPRRIAVNTLAPGAIETDFGGGTVRDNAEVNAYVASQTALGRVGLP
                     DDIGGVVAMLLSKESGWINAQRIEASGGMFI"
     aSDomain        complement(12365..12874)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS19290_PKS_KR.1"
                     /evalue="1.10E-12"
                     /label="EKH80_RS19290_PKS_KR.1"
                     /locus_tag="EKH80_RS19290"
                     /protein_end="177"
                     /protein_start="7"
                     /score="40.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LITGGSRGLGKNMVLRLAEHGTDVVLTYRSNQAEAEAVVASVTKL
                     GRRAVALPLDVGKTSSFAAFAGQLRTVLQEQWQRDRFDYLVNNAGIGIHASFAETTEAQ
                     FDELVNVHFKGAFFLTQALLPLIADGGRVLNVSSGLARFALPGYAAYASMKGAIEVLTR
                     YLAKELG"
     CDS_motif       complement(12809..12874)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS19290_0001"
                     /evalue="4.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH80_RS19290"
                     /protein_end="29"
                     /protein_start="7"
                     /score="16.0"
                     /tool="antismash"
                     /translation="LITGGSRGLGKNMVLRLAEHGT"
     misc_feature    12934..12949
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.62"
                     /tool="antismash"
     gene            13023..13925
                     /locus_tag="EKH80_RS19295"
                     /old_locus_tag="EKH80_19300"
     CDS             13023..13925
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016902251.1"
                     /locus_tag="EKH80_RS19295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19300"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_126686429.1"
                     /transl_table=11
                     /translation="MNRIEAMHVFVRVAELASFTKAADSLGLPKASASTAVQQLEVQLG
                     TQLLHRTTRRVQMTQDGQRYYERCKDVLADLDELGTMFQQAPQALSGRLRVDMNSGVAR
                     HVIDHLPKFLREHPGIEVELSSSDRRVDVVAEGFDCVVRVGTLSDSSLIVRRLGQYRIV
                     NCASPAYLQEHGTPQNLEDLTHHRLIHYVSVMGQRPSGFEYMEGAQCRYVPMQGVLTVN
                     SIEAYTHGCLAGLGIIQTPRGGVQHQLLAGRLVEVLPQYEAEPMPVSLLYAQRRNLSVR
                     VQVFMDWLAKLLAPYLDRV"
     gene            complement(13932..14843)
                     /locus_tag="EKH80_RS19300"
                     /old_locus_tag="EKH80_19305"
     CDS             complement(13932..14843)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /locus_tag="EKH80_RS19300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19305"
                     /product="helix-turn-helix domain-containing GNAT family
                     N-acetyltransferase"
                     /protein_id="WP_126686430.1"
                     /transl_table=11
                     /translation="MNTHQTQAQLAQQIAAIREFNRYYTARLGLLRRRHLDGEFALTEA
                     RILYEVSAQPKVTASALQETLELDAGYMSRLLSGLIRRKLIRRVSSDTDAREKPLLLTA
                     VGQKAVARLNEQSMAHIHGMLTHLSAADRAALVTSLAGVRSLLEDRRQAPLRITRLTAP
                     DDHALALLNEYYEAVHVVQRDKPGSIQQLIDDPASGIWLAYLDDEVVGCVVLRKLTTLP
                     HASECKRLYVKPSARGRHIADKLLDAQEAYARSQGIEWIYLDSYDDLKAAIWLYEKRGY
                     ERCERYNDNPQATVFMRKHLDT"
     misc_feature    14869..14881
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(14931..15665)
                     /locus_tag="EKH80_RS19305"
                     /old_locus_tag="EKH80_19310"
     CDS             complement(14931..15665)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008434554.1"
                     /locus_tag="EKH80_RS19305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19310"
                     /product="2OG-Fe dioxygenase family protein"
                     /protein_id="WP_126686431.1"
                     /transl_table=11
                     /translation="MQIPIDSPVCAPLDAVKRDGYSFVTAEVMHPLLRASGDLSDWNAF
                     AASWNQLGPDPYLAATGRQRRRRHATYTATPNDGVELAPHQPHYQSLLYNRLQGDIERW
                     FEPVDSAMANGKSLRTILAFCNDFFSSLAPATPSWHVEVHQFRIEASSTSAGEPTPEGS
                     HRDGVDFVLVLLIDRCNIASGTTTIHSPDGKPLGHFTLTHPFDAALIHDPRVFHGVTPV
                     TPITPDEPAHRDVLVVTFRARS"
     gene            complement(15806..16204)
                     /locus_tag="EKH80_RS19310"
                     /old_locus_tag="EKH80_19315"
     CDS             complement(15806..16204)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019466172.1"
                     /locus_tag="EKH80_RS19310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19315"
                     /product="biopolymer transporter ExbD"
                     /protein_id="WP_126686432.1"
                     /transl_table=11
                     /translation="MAFSVRASHDVMAQINVTPLVDVMLVLLIIFMISAPIITHKTKLD
                     LPQGSSHFTEAATPIHLAVQADGAMFWNGTPVSLDQLRTQLAIAATQSTQPALEIDAAD
                     GAAYEAVARVLAEAKAQGLARIDMLGMH"
     misc_feature    complement(16158..16171)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            16352..16834
                     /locus_tag="EKH80_RS19315"
                     /old_locus_tag="EKH80_19320"
     CDS             16352..16834
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023363.4"
                     /locus_tag="EKH80_RS19315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19320"
                     /product="DUF3455 domain-containing protein"
                     /protein_id="WP_158628893.1"
                     /transl_table=11
                     /translation="MPSTRVHWFFVSIVFAGALHAQEPAKRPAIEAFAKGVQIYACTPS
                     HGSFAWVLKAPEASLSDARGHVFGKHFAGPSWQAEDGSVVVGEALNLSPSPDAGSIAWL
                     VLHAKSHTGAGEMASVQYVVRTRTEGGVAPAMGCDAVHAGTEVRVPYSAVYLFFRG"
     misc_feature    16988..17002
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.15"
                     /tool="antismash"
     misc_feature    17041..17056
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            17244..17948
                     /locus_tag="EKH80_RS19320"
                     /old_locus_tag="EKH80_19325"
     CDS             17244..17948
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015448174.1"
                     /locus_tag="EKH80_RS19320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19325"
                     /product="transposase"
                     /protein_id="WP_126686434.1"
                     /transl_table=11
                     /translation="MPRAPRFDLAYVPQHIIQRGHDGAECFYAPADYRSYLVQLLHASS
                     RWQCLVHAYVLMPNHVHLLVTPSCVGALAHMMQGLGRNYVSYFNSTYHRSGTLWEGRYK
                     SCLVGSDYVLSCQCYIELNPVRSGLVGEPSSYPWSSYACNALGKPDPVVVPHAEFVALG
                     NYREQCMRAYRQLFAADIEPAVLREIRTYIQQQRALGSPAFQERVEAMLGRCAKARPAH
                     RPRKRPEAIGRV"
     gene            complement(17999..18364)
                     /locus_tag="EKH80_RS19325"
                     /old_locus_tag="EKH80_19330"
     CDS             complement(17999..18364)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007809277.1"
                     /locus_tag="EKH80_RS19325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19330"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_126686435.1"
                     /transl_table=11
                     /translation="MSPRTEASVRNAGTKLPLLHKAVPVFAALGDETRLRLIALLCTGS
                     ALSIAQLTAGTEITRQAVTKHLQVLADAGLVRDLRQGRERLWEFEPSRLEEARRSLDAI
                     AQQWDQALLRLKAMLEK"
     gene            complement(18348..18809)
                     /locus_tag="EKH80_RS19330"
                     /old_locus_tag="EKH80_19335"
     CDS             complement(18348..18809)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (6-145). E-value:
                     4.6e-11. Score: 35.3. Matches aSDomain:
                     nrpspksdomains_EKH80_RS19330_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008213115.1"
                     /locus_tag="EKH80_RS19330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19335"
                     /product="SRPBCC family protein"
                     /protein_id="WP_126686436.1"
                     /transl_table=11
                     /translation="MNSSTDRIERQVLIKAPRAKVWQALADAESFGEWFGVALKGKRFV
                     AGEPCEGNITYPGYEHLVMKVVVDRVEPERLLSFRWHPYAIDPDVDYSQEPTTLVTFEL
                     EESSGGTLLRVVESGFDRIPAHRRQEAFRMNNSGWEEQMNNIDAYVASH"
     aSDomain        complement(18375..18791)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS19330_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.60E-11"
                     /label="EKH80_RS19330_Polyketide_cyc2.1"
                     /locus_tag="EKH80_RS19330"
                     /protein_end="145"
                     /protein_start="6"
                     /score="35.3"
                     /tool="antismash"
                     /translation="RIERQVLIKAPRAKVWQALADAESFGEWFGVALKGKRFVAGEPCE
                     GNITYPGYEHLVMKVVVDRVEPERLLSFRWHPYAIDPDVDYSQEPTTLVTFELEESSGG
                     TLLRVVESGFDRIPAHRRQEAFRMNNSGWEEQMNN"
     gene            18998..19363
                     /locus_tag="EKH80_RS19335"
                     /old_locus_tag="EKH80_19340"
     CDS             18998..19363
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511808.1"
                     /locus_tag="EKH80_RS19335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19340"
                     /product="YciI family protein"
                     /protein_id="WP_126686437.1"
                     /transl_table=11
                     /translation="MQYLLMLFAEEKAWGRMSSADQERGVAAYGAYTQALKEAGVWVGS
                     NRLQNTDSATTVRVVDGKSQVLDGPYADSKEQLAGYYLIEAADLDAALGWAARCPGAGH
                     GTIEVRPVWPTYGGSPS"
     gene            19360..20613
                     /locus_tag="EKH80_RS19340"
                     /old_locus_tag="EKH80_19345"
     CDS             19360..20613
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007511806.1"
                     /locus_tag="EKH80_RS19340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_19345"
                     /product="DUF6596 domain-containing protein"
                     /protein_id="WP_230473832.1"
                     /transl_table=11
                     /translation="MSEGACARAAANAVARRSYGKLLAYLAADMHDVSAAEDALSEAFA
                     AALADWPLHGCPDHPESWLMTVARRKGIDGVRRRRSGEAASVQLQAIADMRAECVDSGE
                     EEAFPDRRLALLFACAHPAIDVGIRAPLMLQTVLGMDAKTIASAFLVSPEAMGKRLARA
                     KQKIREAGIPFVIPERDAWNERLEGVLTAIYATYAEGWSDPGDADLMRRDLADEALFLA
                     RLLAELLPQEPETLGLLACMLYTEARRGARRNAQGEYVPLAEQDTLLWEAGMIDEAEAL
                     LRRASAFRRIGRYQLEAALQSAHVERRRSGRNDWTPEVQLYDALHALTGSPVVALNRAL
                     AVAELEGPEAAIAIIRSLSEDRRMADYQSYWAARAALFARVGDVREALHAYDMAIGLAR
                     DPAVRHFLQRQQSILETK"
     misc_feature    20770..20782
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    21844..21860
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.74"
                     /tool="antismash"
ORIGIN
        1 acccacgctc gctgctcgga cgctttcgtt acggcggcgt gctggtagcc atcatcatca
       61 ccttcctgtt gttcaacagc attttcgtgg tgtcgcccag tgaagaggcg gggacgcgct
      121 ggatgggtgg tacgccgatg acctcggtgc cgctcaagac cggcgtgcat ttcaaggtac
      181 cgttcttcga atccgtggat cgcctgcaga caagccgttc ggtctacgtg ctgaatggtc
      241 tggacgttta taccaacgac aaccagaaag tcaccatcga cgtcagcctg atctacaaga
      301 tacccagctc cgccgtcatg aatctgcttt atcaggttgg gcgcgcaggt tcagtggatg
      361 tcgaaaccac catcttgccg gtggtgcgcg atcgtgcgct ggcggctttc gcgcgctaca
      421 acaccctaac catctccgac cagcgtacac aaatcaccgc gcaaatgcgc cgcgacatca
      481 gcgatgcctt gcagcgattg ttcaacgtgg acgtgatcga cgtgcagctg gtcggcatcc
      541 attactcgcc gatcttcgac caatccatcg aagaagccgt acgcgccaag aacctggcgg
      601 tgcaggcgga gaatacggtg gcgcagaagc gctacgaagg cgaacagaaa accgttaccg
      661 cgcacgcgga agccaccgcg gcggtggagc gcgccaatgg tgaagcgcag gccaccgtgc
      721 tgcaggcgca ggctcaggcc aaagccattg aaaccgtggg ccaggcgctg aaaagcaatc
      781 ccgaatacag ccgtttctat ggcttgcagc attggaacgg cattcttccc caggtggtgg
      841 gcgcgggttc cattccgatg atcgatctga gcaaggggca ggacaccggt aaatagctgc
      901 tgtctctaag gatggcctga aaaaaatccg agatggactt tttcagtgcg taggctggga
      961 tggcaatccc agcatcggga cgtcgtgtgg aaagccggga ttgtcatccc aggctacgcg
     1021 ttacaccacc agccttcctg gccggttcgt cattcagagg aattcgcgta cggatgcttg
     1081 tcggcgagct tgccgttgcc ggtataggtg ggcgcgcggg gcgtgtgctc gtccatgctg
     1141 atcaccacgc gattgcggcc gtcgcgcttg gcgcgataaa gcgcgctatc ggcggcaagt
     1201 agcagtcgcc gcaggtcgta gccgtagtgg gccgtggagg cgataccgaa gctggcggta
     1261 agtgcgacat ggtcttgcgt gtcgttggtg gtggcctgca acgccaggcg gatcttttct
     1321 gcgcgttcga gcgcctggat gagcgtggat tccggcagca gtatgccgaa ttcttcaccg
     1381 ccgatacggc cgaatacgtc gcaggagtgc agatgctgct ggcagaccga cacggcccgc
     1441 ttcaatgcgg tgtcgcccac gacgtggccg tgcgtgtcgt tgatgtcctt gaagtggtcc
     1501 aggtcgatca gcaccaggca ggccccacgc agcgacttgg ccgcgtagcg cagggtctgt
     1561 tccgcttctt cgacgaaatg ctggcgattg aagataccgg taagaccatc ccggcgcgcc
     1621 aggcgcatga agcgcagttg cgagcgcttg aggcgataca gccagaaggc gatcgaggcc
     1681 agcaccgtta gcagcagcgt gatgtaaagg cgactggtca cgacggcttt gccgttgagt
     1741 gcctgctgca gctgcaggat ctggttttgc ttgttcagtt cgttgagttc gattttcttg
     1801 gtttctacct gctgtttgac gatctgatag gagagggcct tttcgcggat gtcatcgaga
     1861 tgttctttgt cggcagccac atatttttcg tgataggcga gcgcttcgcg cagattgccg
     1921 tactgctgct caacttgata aagaagctgg taggccttga tcaggggttc ggtgaggttg
     1981 ctcctggagg ccacatctac ggtggccatg gcatattttt gggccagcgc aacgttgcct
     2041 ttcttccagt aggcctgcgc gagaagcacg ttgtattcgg cggtcagtgc ttgatagttg
     2101 agtcctttca cttcatcgtt ggtggcttgc agaatggcga gggcatcatc cgttctgtcc
     2161 tgctgcaagt ccaaaaccgc tatgtcgcgc cgtatcgtgt cggccgctag tttgtcccca
     2221 acatcaaggc atcgcttgat gcctttctga aacagttcgc cggctattcg cttttggccg
     2281 ccgcgaattt cggcgtgcaa ttggagcata tggccgatgc agccaatatt gcccttcgga
     2341 taatcggcga tgatctgctt ggcatagcct gcggcgaggt catattgacc gacttcgcta
     2401 agtagctgcg aggcttctcc aaggatcgga aagcgcgctc cttgatcggc aacgggcggg
     2461 aggttttcca gtgcgcgatc caggtattcg aaggcttcct cgtagtgatg ctggacgccc
     2521 aggacgttga tcagggcggc tgtcgcccgt gttcttagct cgttgtcggg ggcttgcttg
     2581 accactgcct caagcagcga cttggccttg tcttcccggc cgctgtagtc ggcctgccag
     2641 ccttccagaa agcgaagacg ccacttctgt gcttcggaca tttcagttgt ccggccttcg
     2701 agcccgtcaa ggagtctgac aaagccaggg ttgtcggtgg tttttatgct gtcggcctgg
     2761 accagtagtt gcgtgatgtc gttcgaagca tgtacggcgg ccatgcctgt gcttgcgagc
     2821 atgacgagca gcaggaagat tcctgcgtac ggcttccggc gtttggagcc ggcggcgtgc
     2881 atttactgag cggaagttgt cgaggaagaa gacggctggc gcgtgtctct ctcgccgggt
     2941 tcgtcatcct cttcttcttc ttcctcctcc tcttcgcccg gcatgacata accgacaggt
     3001 gttttcccct gcagcagtgc cagcaactgg gcagcatcgt tgttcaagat ggccgagcga
     3061 agcgggcctt caatcgaggc gttgccaagc gctagttcca ttgcgtcctt ggtgatgtcg
     3121 ccccatcgag cttcaccgcc tatggtttcc aaaaagcgca tgacattcga catccaaaat
     3181 acccccgtat ccaatgcttg ggcgcccctc ggtgggcaat cgtcatcgtc cctgctgagt
     3241 gactgacgca tcatcatatc gcgcaacgga tggaggcgtc gccgatatct gcgggaacaa
     3301 ggcgttgcct cccttgttta tccctgcgaa tggccgctct caggccaatg cctccaggcg
     3361 ggcgcgaatt tcatggtcgg cctccagcgg tcgagccggc gggatggcca gcgtgtcggc
     3421 catgccgaat tcagccagtg gcaaggcccc tagcgcaagc aactccctgc gaggggactg
     3481 gaagggcagg gtggcggcac gatagatcac cacttgatgg tccagggtgt agtgccgcgc
     3541 gagcacatcc accagcacct ggcgatgtgc ctcgccggtc gagaaacgca tgagtgtttt
     3601 gtcgcccgct accccgacct gccacaggat cagccacgcg ctcggatcga tacagcggcg
     3661 ataaagcatg aactgactgg cttcgtaatg ctggcagccg cgggcgcctg ggtcgatgcc
     3721 gagatcggca tacaggcagt cttcggagga aatgcccggt tccatgtggg cgtggtagcc
     3781 cttgctgcgc gcggtccgga tggccttgtg cgggacccag gcgaagacgc ctgggtgtcc
     3841 gtagaacacg ccgcagacgc gcctgccggc acttacctcg gccatgatgg cgttcaccat
     3901 ctgccggtag gtcttcatcc tcgacttgcc ttcctggtag tacggctgca ggctgcgcac
     3961 gtcttcgttc atgccttgca gccacagttc gacgatgccg tcggacacca gggtgaacac
     4021 cacatcggcc tgttcgatat aggcgtgggc gcgccggctg aggtgggatc ccagcgtcat
     4081 gcctataccc acgcaggcca ggcttccctt gggctgtatg ctgtccaaaa cttccatccc
     4141 ctactgcttg cgtagcggta ttgtgccctg ggcggcgatg gtcgagcgcc ttgacagctt
     4201 ggatgggagc agacttgagc gagcgcgcga caccggatga ttgggatttg cctgatcctg
     4261 aaagatccgg ccgaacgttc gtctacgtgc tgccgtccca gggtgaggac ttgaccaagc
     4321 tgggtttcac gcaagatccg gtgcagcggt ttcgcagttt ccatccgcgg ttcttcgctt
     4381 tgttcgacct ggaaagcggc ctgctggtgg agaccgggcg gctgcgcgac gcacggcgat
     4441 tggagcggtt gctgatcgag cgttggccgg accatcgcgc cccggctccc ttgttggtgg
     4501 cggaggcagc cggcggtcac accgaatggt tccgtggtat agggggagag gtggatgcat
     4561 tcgtacgccg tacagcggag cgttacggct atgcattgca tgcgcccttg agcgcctggc
     4621 tgcgtgcgcg cttttcggag cgggcggacc agctttacga gtggtcgcag cgtctgctgg
     4681 agatgatcga gtggcaaaca gcgaatctgc cgccggagga acgcaatcta cgttatgcca
     4741 aggcgctgcg tgacaatctc gacgcttgtc acgcagtcgg catgaatctg catgcactgt
     4801 tgccggccag ggtgatggcc tggtatgcat ccgcgcgagg caacggctag atgcagctcg
     4861 tccggtgacg ctgctgacag tatgttgtca gcagcctcga ttaagctgcg catacctttt
     4921 ttgtggaacc catggacatg accacgccaa gcatcaccct gtacgccacc cgccctggtt
     4981 tcggcatgcc ggaaaccagt ccgttcgtga tcaagaccga agtgcagcta aaaatggcgg
     5041 atctgtcgta tggacgggaa tccaccattc cgccgttggc gcccaagggc aaagtgccgt
     5101 acctgttgga tgatggcgaa gtggtgtgcg attccacctt tattcgcgcg catctggaac
     5161 gcaagtatgg cgtggatctg gacgagggcc tggacgcgca ccagcgtgcg caatcctggg
     5221 cgatcgaacg gatgctggaa gatcatctgt atttcgccat ggtgtggttc cgctggatcg
     5281 tgccggagaa tttcgccaag gggccggcgc aatttgccaa cggcgcgccg gaggagcaac
     5341 gcgaagccct gcgccgtgag atgcagtcgc gcaaggatgg cgacttgcgt agccacggta
     5401 tcggccggca ttcggcgggc gagatcgcgg ccctgggcgt gcgttccatc gatgctctgg
     5461 ccgccttgct gggcgacaag ccttatttga tgggcgaaag aatgaccgct gtggatgcga
     5521 cggccttggg ggtgttggcg tccatcctta cgtcgttctt cgatacgccg ctgcgcgatg
     5581 ccgtggccag ccggccgaac ctggtcgcgt acgtgagcaa gctgatgcaa cggtattacc
     5641 cggagcatgc gtgggagccg gccgcggagg ccgtttgagg ggcgcagccg gcgcgggtag
     5701 gctgggacga tgatcccagc atcgcgcggt ggcgtacatg gcgatgctgg gtttcgcgac
     5761 ccagcctacc aaggcgggtc gcaaggtgaa cgaactcatc cgcatgccag ggacgcctac
     5821 gcggatttga tcggcgcagt cctaggctgt agctgtcttc cagatccgag gagtcgccca
     5881 tggaagtcag tttcaataac tggggcgagg ccgtcgcgtt cctctccgag cgtactgata
     5941 tcgccctgga aggattgatg gcgctcagtg cgcaacaaat ggtggatcag caagtcattg
     6001 ccgcactcct ggcgtcccat acccacctga gggccgccgc agacgcgtgg cggcagatgg
     6061 cttcggctac cttgccgatc acccatgtgc gcagcctgca gaacgaccag ccggagtcgg
     6121 tgcgagtagc ctattcggaa cgcatggcct attgggagga actcttccgc aaggccattc
     6181 cccagaagag cgaatgaggc aaaaagcggg caattggcgt taaaagcgtg cggaggccgt
     6241 agcggcgtgc aaccatatga cgctgtagtt cttcacatct tcattgcgcc agccctatga
     6301 ccaagcgcct tgctttccga cgcgttattg cgtccgtcgt tttcgttatc gcggtcatcg
     6361 ccgcgcaggg cgcgtccgcg caaacgacgt ccaccgtgca gttgcagaac ctcacctgga
     6421 ccgagctgcg cgagcagatt cacgccggca agaccacgct gatcattccc atcggcggca
     6481 ccgagcaaag cggtccgtat atcgcggtgg gcaagcacaa tgtgcgtgcg gcttatctgg
     6541 cggaccggat cgcgcaaaaa ctgggcaatg cgctggtcgc tccggtggtg gcctatgtgc
     6601 cggaaggcgg ctatgcgccg cccacctcgc acatgcgctt tcccggcacg atcaccgttc
     6661 cggatgacgt gttcgagaaa atgctcgaag cggccgccaa cagtttcgcg gtgcatggct
     6721 ttcgcaacat cgtcttcctg ggtgaccacg gcggttacca gaaggacctc aagcaggtag
     6781 tggctcgcct caacaaagcc tgggcgggag cgaatgcgcg ggccatcctg ccggcggcgt
     6841 attacgaggc ttcttccgat ggctacgcac agctgctgcg ccagcgcggt tttcgcgacg
     6901 atgaaatcgg cacccatgcc ggtcttgccg atacttcgtt gcagcttgcg gtggcgccgc
     6961 agatggtacg aaccaatcaa ctgcgcaatg cccccaagcc tggcgcggcc gacggcgtgt
     7021 atggcggcga tccgcgccga tccacggcgg aactgggtca aatcggcgtg gatgctatag
     7081 tttcgcgcac ggtcgacgcc atccgccagg aaaccgcggg gcattgatcc gatgtcttgg
     7141 acctccccct tcgaaagtct tctcaaaata agggaatctg ccgtgaaatt tgatcgtttt
     7201 gggcgtcttg ccttgcgtgc cggcgccgtg ctggccggtt tgtgtgtcac cgccgcggcc
     7261 gcggcgcaaa cggttcagac cgttcccggc atgccgccgg tcaccaatcc gcacgacatg
     7321 tacagcaacg cgggcttcaa catgttcagc ccggcggtga agggtgcgct gccgcggatc
     7381 tacgttccga acctgcgttc gaacgacgtg tacgtgatcg atccggccac gttcaaggtg
     7441 gtcgaccggt ttgcagtcgg ccgcagccct cagcacgtgg tgccggcgtg ggatctgaaa
     7501 acactgtggg tgaccaacaa cgccgaaggc cgcaatgacg gcagcctgac gccgatcgat
     7561 ccgatgaccg gcaagccggg caaggccgat ccggtggatg atccgtacaa catgtacttc
     7621 acgccggacg gcaaggaagc catcgtggtg gccgaagcct tcgcacgcct cgatttccgc
     7681 gatccgcata cgatggcact gaaatcccgc ctgccggcgc ccgaatgcaa aggcatcaac
     7741 cacgcggatt tctcgatcga cggcaagtac gccatcttta cctgcgaatt cggcggcaag
     7801 ctggtgaaga tcgacatggt caaccgcaag gttctcggct acctgcagct caacaagcgg
     7861 ggcatgccgc aggatattcg cgtgtcgccg gacggcaagg tgttctacgt ggccgacatg
     7921 atggcggacg gcgtgtacct gatcgacggc gacagcttca agcaggtcgg cttcgtcaag
     7981 accggcatcg gcacgcacgg cctgtatccg agccgcgacg gcaccaagct ttacgttgcc
     8041 aatcgcggtt caaacaaagt gcacggcccg cgtaatggcc caggcagcgt gtcggtgatc
     8101 gatttcgcca cgcgcagcgt ggtggcgaac tggccgattc cgggcggcgg cagtcccgac
     8161 atgggcaacg tcacggccga cggcaagtgg ttgtggctgt cgggccgttt cgatgacgtg
     8221 gtgtatgcgt tcgataccgc gaccggcaag gtgcagatca tcaaggtggg gatggagccg
     8281 catggtctgg cggtttggcc gcaacccggg cggttctcgc tgggacacac cggcatcatg
     8341 cgttgatgca aaaaagaggc cggcattgcc ggcctttttc acaggttggg gttggtagcc
     8401 caacctacga gagctggact acgtcgaagc tcgcatccgg atttacgtcc gcgttgtaat
     8461 ccacgtcctt gcgatcaaag ccgaacaggc gcaggaactc atgcttgtag ccggcatagt
     8521 cggtcgtttc ccacaggttc tcggtgctga cttgcggcca tagcgtcttg caggcctgct
     8581 gcacgtcttc gcgcaattcc cagtcatcca ggcgcaggcg gccctcctcg tcggtggacg
     8641 gcagggcacc gtcctggcga tacaggaaat catggaacag gcggttggcc tgctcgatgg
     8701 taccttcgtg gaggcctttc tccttcatga tgcggaacac catcgagacg tacagcggaa
     8761 ttaccggaat ggccgagctg gcctgcgtga ccacggattt catcacgccc acgtaggcgc
     8821 gcaggtgctg tgcggcgtaa tgccggttga gttcttgcgc agtgttgtcc agatgctgct
     8881 tggcctggcc gatggtgccg tgccagtaga tcggccaggt tatttcggtg ccgacgtagc
     8941 tgtaggcgac ggtggtggcg ttatccgcca gcacgccggc cttgctcagc gcgtcgatcc
     9001 atagcgccca gtcttcgccg cccatcacgg cgatggtgtc cttgatttcc tgctcgttgg
     9061 ccggctccac cgtgacctgc accacgctgt ccttgttggt atccaccgag gaggcggtaa
     9121 acggctggcc gatcgtcttc agcgtggaac gcaccaattc gccggtatcg ggcagcttgc
     9181 gtacgggcga agccagcgaa tagatcacca ggtccaccgg gccgcccatg tcgttcttga
     9241 tcagctcgat ggcgcgcgcg cgggtttcat gcgagaacgc atcgccattg atggagcgcg
     9301 aatacaatcc ggcctgcttg gccagtttgt cgaaggcggc ggagttgtac cagccggcgg
     9361 taccgggctt gctgtcgctg gagggttttt cgaagaacac gcccaacgtg gcagcgccgc
     9421 agccgaaggc cgccgtgatg cgtgatgcca ggccatatcc cgtggaggcg ccgatcacca
     9481 gcacgcgctt gggtccggag ccgcaagcgc ctttggcctt ggtgatgccg atctgctcga
     9541 gcacattctt ctcgcagccg agcggatgcg ccgtgacaca gataaagccg cgaaccttgg
     9601 gatggatgac cacgaattag cctcaccgga tgaatacaag gccgccattc taaagggcga
     9661 gggggaccat gcgcctgcgc agggaggggc ttcagtcttc cagatccacc gccccagtgg
     9721 ggttggggaa gcggatgtac acaatcttta cgccttccgt accaggcgtt ccttgtgcga
     9781 ggcggatagt caactcgcac gcccatgcga aaggaggccg ctatgaccac cctcaagcca
     9841 tccaacgcac cccatgaagc ccccggccgc gaagccggcg agccctatga tccgcacaaa
     9901 cggcggggcc ccccgcaacg cctggaagac accaacgcca gcggcgacgc cctcaatgac
     9961 accggcgagg acaaccagcg ccaaaaagag gaggaatgaa tcaggccccg tcggcggtga
    10021 agcctacctt ggcatggctg ccgtcacaga atggtttgtt ctggctatga ccgcagcggc
    10081 ataggtacgt gccggtgacg cgcgccacca tgcgcccggt gccgctgatg atttccaggt
    10141 tgccgcggac acgcagcggc ccgttcattt gcggatcgat ctgcagcggc ccatcgcgtg
    10201 cggtcagctc ctcgttcgac gtaccggtcg ggggctcgcc gctggcgttg aatcccacat
    10261 cgtgatgcga gccatcgcag aacggtttgt tcttcgaggc cccgcagcgg cacagcgtgg
    10321 cgcggaaacc ggcaggtttg ccggcgaggc gcagatcgcc acgaaacgca taaggccctg
    10381 cctcacggac ggccgcgaga ttgaccggcg gagcggattc gtccggtcgt ccatcgcggc
    10441 gctggtattg gatggcgccg gaagggcagg cgtgcgcgat gtcgaccaat ctttccacat
    10501 ccatcgcatc gggatggatc cacggccctt gcacgttggc gagaaacact ttcggcgcac
    10561 ccgtcacgca gaagcgcgca tggatgcagc gcttggcttc gaagcgcagc gtgagcttct
    10621 cgccctcgac ctgttcgatg ccatcctcca ccacggtgga ggccggtgct gccggagcgg
    10681 gtgcagcagc gagtgcaggc gttgatgccg caaccgcagc cgatggtgca gggcgagcaa
    10741 gatcgaatcc ctgttcggcc tgttgcgaga gatgcttgaa caccgccgcc gcagcgatgg
    10801 tgcgcggatc gttcgatgcg ctcagccgtt cggccgcttc cgtcaattgc tcaaagcgct
    10861 ccaggaaaaa gcgccgcgcg ctggggccag gcggcaaggg agaggtatcg cgcaaggtga
    10921 tgaaggtaac gcccgcgtgg caatccggat tcgatggtcc ggccggcagt cgcgccgcgc
    10981 gttcggccaa cggtgccaac gcgcgcatca agccaatgcc caggtccagc gacaggcatt
    11041 tgtccgggtc gggcgccggt acagcgtacg agtaggccag caggcgttgc atcaaaccgt
    11101 aggcggcatt ggcgaggtcg acagtggcga tggcatcttc gttttccagc cacacgcgtc
    11161 cctcggggcg cggcggacga cgcagcaccg gattggtggc ggcagggaag gccggcttga
    11221 acgaagggtc ggcagccagc aaggcttcgt attccgcgcg gatcgcggcg aaacgctggt
    11281 aatgcgagtt ctccgtattt tcctgcgccc cttcgccctg ggtaatgatg gactcaaacg
    11341 cggccagcgc cgtcttcaga cagatgacct tgttcgcgcc gggcagcgat acctctgctt
    11401 tggacaactg caaggcaggg tcgccacaca tggcgccggc ttcgccatac ttttgcacca
    11461 tgccgcgcag gccattgccc aaggtttgat aaaactcgcc caccgtttcg taattgatac
    11521 ccatcggcgt aaggcgcgga ccgtttgccc cacgcaagaa gtggcgctcg ggctcgaaac
    11581 cttcgccatc cggttcggtg gagccggccg gtcgctccag gtagatgaaa tgctgcagcg
    11641 ttgcccgatt gaacggcgcc agcttcacca ccacaccggc cggcaggtag ccgggatcga
    11701 gcggaaaatt cgagcgcccg aggcgtgggg caccacccag tgccacggtg atgttccaaa
    11761 ccgacatcag atggcccatc tcctcgatcg ccacctgcag gatgctgcgt ttccagcgcg
    11821 tgatcgcttc gagctgatcg gctgtcacgc cttcttccgc tgaggatttc agcgaaaacg
    11881 ctgcgtagag ataggtgcac atcaagcagt gttcgagctc ggccgcttcg tagagcgcgt
    11941 gcagcgcctg ttcgcggctg ggaacggtat gcgaggggct atagctgacc acggctggat
    12001 cccttagggt gtcaagaaag agaaggtaca ccgattgggc ttgcctgcgg ctgtgtcgta
    12061 ggctgggttg tgaaaccccg catcgccatg cgtgcagccg cgcgatgttg ggattctcat
    12121 cccagcctac ctttcagatg aacattccac cggaagcctc gatccgctgc gcattgatcc
    12181 atccgctttc cttcgacagc agcatggcca ccacgccgcc gatatcgtcc ggcaaaccca
    12241 cgcggcccag cgccgtctgc gacgccacgt aggcattcac ctcggcgttg tcgcgcaccg
    12301 taccgccacc gaagtcggtc tcgatcgcgc ccggcgccag cgtgttgact gcaatgcggc
    12361 gtgggccaag ctccttggcc agatagcgcg tcagcacctc gatcgcgcct ttcatcgagg
    12421 catacgccgc atagccgggc agggcaaagc gcgccaggcc gctggagacg ttgaggacgc
    12481 gtccgccgtc ggcgatcaac ggcagcaagg cctgggtcag gaagaacgcg cccttgaagt
    12541 ggacgttcac cagttcatcg aactgcgcct cggtggtttc ggcgaagctg gcatggatgc
    12601 caatgccggc attgttgacc aggtagtcga aacgatcgcg ctgccattgc tcctgcagca
    12661 ccgtgcgcaa ctgcccggcg aaggcggcaa agctggaagt cttgcccacg tccagcggca
    12721 gcgcgacggc gcggcggcca agcttcgtca ccgacgccac cacggcctca gcctcggctt
    12781 gattggaacg gtacgtcagc accacgtcgg tgccgtgttc ggccagtcgc agcaccatgt
    12841 tcttgccaag gccgcggctg ccgccggtga tcagggcgat cggggttgtg ttcatggacg
    12901 tctccttgga aaggaaggga agggatcaac ggaaacgaga atattgatct gtactcgccg
    12961 cataaatcgt ccgatcatga gtgctgtgtt cgtgaatgac gaacaatcga gtggggcagg
    13021 gcatgaaccg gatcgaggcc atgcacgtct tcgtgcgagt ggcagaactg gccagtttta
    13081 ccaaggccgc cgacagtctg gggttgccca aggccagcgc atccacggcc gtgcagcaac
    13141 tggaagtgca gctcggcacg cagctcctgc atcgaaccac acgccgggtg caaatgacgc
    13201 aagacggcca gcgctactac gagcgctgca aggacgtgct ggccgacctg gacgaattgg
    13261 gcacgatgtt ccagcaggct ccgcaagctt tgagcggccg cttgcgggtg gacatgaata
    13321 gcggcgtcgc caggcacgtc atcgaccatc tgccgaaatt cctgcgcgag catccgggga
    13381 tcgaggtgga gctgagcagc agcgatcgtc gtgtcgacgt agtggcggaa ggcttcgatt
    13441 gcgtggtgcg ggtgggcacg ctcagcgatt ccagcttgat cgtgcggcgg ctggggcagt
    13501 atcgcatcgt caactgtgcg agtcctgctt atctacagga gcacggtacg ccgcaaaact
    13561 tggaggacct cacccatcac cggctgatcc actacgtatc ggtgatggga cagcggccgt
    13621 ccggcttcga atacatggaa ggggcgcagt gtcgctacgt gcccatgcaa ggcgtgctta
    13681 ccgtcaacag catcgaagcg tacacccatg ggtgcctggc cggactgggc atcatccaga
    13741 cacccagagg aggtgtgcag caccagcttc tggccggacg cctggtggaa gtgttgccgc
    13801 aatacgaagc ggagcccatg ccggtgtcgc tgctgtatgc gcaacggcgt aatttgtcgg
    13861 tgcgcgtgca ggtgttcatg gattggctgg cgaagctgct tgcgccatat ttggatcgtg
    13921 tctgaatcac gctacgtatc gaggtgtttg cgcatgaata cggtggcctg ggggttgtcg
    13981 ttgtagcgtt cgcaacgctc gtagccccgc ttttcatata gccagatggc ggccttcagg
    14041 tcgtcgtagc tgtccagata gatccattcg atgccttggc tgcgcgcgta cgcctcctgg
    14101 gcatcgagca gcttgtcggc aatgtgccgg ccgcgtgcgc tgggtttcac gtacaggcgc
    14161 ttgcattcgc tggcgtgcgg cagggtggtc agcttgcgca gcacgacgca tcccaccacc
    14221 tcatcgtcca gataggcgag ccatattccc gacgcgggat cgtcgatgag ctgctgaatg
    14281 ctgccgggct tgtcccgctg cacgacatgc acggcttcgt agtactcatt aagaagggcc
    14341 aatgcatgat catcaggcgc agtcaggcga gtgatgcgca ggggggcttg ccggcgatct
    14401 tcaagcaggc tgcggacacc cgccagggaa gtgaccaatg ctgcgcgatc ggccgcgctc
    14461 aggtgtgtaa gcatgccgtg gatatgcgcc atggactgct cgttgaggcg cgcgacggcc
    14521 ttttgtccga ctgcggtgag cagcaacggt ttctcgcgag catccgtgtc ggagcttacg
    14581 cggcggatca gcttgcgccg gatcaagccc gatagaaggc ggctcatata gccggcatcc
    14641 agttccagcg tttcctgcag cgcggacgcc gtcacctttg gttgggcact cacctcgtag
    14701 aggatgcgag cctcggtcag tgcgaactcg ccgtcgaggt gtctgcggcg cagcaatcca
    14761 agccgggctg tgtagtagcg gttgaactca cgtatcgcgg caatctgctg cgcgagttgc
    14821 gcttgcgtct ggtgggtgtt catgggttgc cactctaaat ccaaatagtt gcttttggca
    14881 actattcgga cgggcgcgcg aaattcgtgc ccggcttcgg gttgcgtgcg tcaggagcgg
    14941 gcgcggaagg tcaccaccag cacatcgcga tgtgccggct cgtcaggggt gatcggggtt
    15001 accggcgtca cgccatggaa cacgcgcgga tcgtggatca gcgccgcatc gaacggatgg
    15061 gtgagggtga aatggccaag gggcttgcca tccgggctgt ggatggtggt ggtgccgctg
    15121 gcgatgttgc agcgatcgat cagcagtacc agcacgaaat ccacgccgtc acgatggctg
    15181 ccttccggag tgggttcgcc ggcggaggta gagcttgcct cgatacggaa ttgatggact
    15241 tcgacatgcc agcttggggt ggccggtgcg agcgagctga agaagtcatt gcagaacgcg
    15301 aggatggtgc ggaggctttt accgttcgcc atggcggaat cgaccggctc gaaccagcgc
    15361 tcgatatcgc cttgcaggcg gttgtatagc agcgattggt aatgcggctg atgcggcgcc
    15421 agctcgacac cgtcgttggg cgtggccgta taagtggcgt ggcgacgtcg ccgctgccgc
    15481 cccgttgcgg cgagataagg atcgggaccg agctggttcc agcttgcagc gaaggcgttc
    15541 caatccgaca aatcgcccga tgctcgcagc agaggatgca tgacttccgc ggtgacgaag
    15601 gagtagccgt cgcgcttcac agcgtcgagc ggcgcgcaga cgggcgaatc gatggggatt
    15661 tgcatggagg gattatatag ccgggactcc gctaccctgc gctccccctc cctgagggag
    15721 cgggagcgca ggcttaggtt gtaaaaccct gccttgccat gcttgcaacg cacgcgatgc
    15781 cgggattgcc attccagcct acgtgctaat gcattccgag catgtcgatc ctggccagcc
    15841 cctgcgcctt tgcttccgcc agcactcttg ccacggcctc gtaggccgcg ccgtcggccg
    15901 catcgatttc cagcgcaggt tgcgtggatt gcgttgcggc aatcgccagc tgcgttcgca
    15961 actggtcgag gcttacgggc gtaccgttcc agaacatcgc gccatcggcc tggaccgcca
    16021 ggtgaatggg ggtggcggct tcggtgaaat ggctggagcc ctgcggcaaa tccaatttcg
    16081 ttttgtgcgt aatgatcggt gcgctgatca tgaagatgat caataaaacc agcatgacgt
    16141 cgaccagcgg cgtcacgttg atctgggcca ttacgtcatg cgatgcacga acagagaaag
    16201 ccatacttcc tcctgggcga acgtgtcgat atcgatgtgc gcccggcatt caaggggaac
    16261 cgggcgacgc cagcttagtg ccggctcgga cataaaagca aagccataag cacttatgct
    16321 gtgccggctg tcatccgata gggagagcat catgccaagc acaagggtgc attggttttt
    16381 cgtatcaatc gttttcgccg gcgcactgca tgcgcaggaa cctgccaagc ggcccgccat
    16441 cgaagcgttt gccaaagggg tgcagatcta cgcctgcaca ccctctcatg gtagctttgc
    16501 ctgggtcttg aaggcgccgg aagcgagctt gagcgatgcc aggggccatg tgttcggcaa
    16561 gcatttcgcg gggcctagct ggcaggctga agacggcagc gtggtggtgg gcgaggcgct
    16621 caacctgtca ccttcgcccg atgccggttc cattgcgtgg ctggtgttgc atgccaagtc
    16681 gcacaccggt gcgggtgaga tggcgagcgt gcagtacgtg gtccgcacgc gtaccgaagg
    16741 tggcgtggca cccgctatgg gctgcgatgc cgtgcatgcg ggtaccgaag tgcgtgtgcc
    16801 ctacagtgcg gtctatctat tctttcgcgg ctgaagactc tcgctggatg cgcgtcgagc
    16861 ggggcgtagg ctgggatgat aatcccagct tctgcgtggc ataccggtgc tgggattgtc
    16921 atccgggcct accaggcgcg catacagtgt ggtgacgggt acgatcgggc aggctcgcgc
    16981 caacggagga cgactcgttc catccagccc cttatggacc cccgccgcga agtgtctttc
    17041 gtcacgccat tttcacggat tagggatgag gctgtagact ggagccttgc gggtaagcct
    17101 gttttgatag gaaaaaacgg gcggcatttg acgatccacg tagatgcgca gcagaacgcg
    17161 acgtttgagc gtgacacggt ctcgtatcga cagggcgaca tcttcataag accgcacgcg
    17221 catcgccgca cggaggcctt tcgatgccac gagcgccacg gttcgatctt gcttatgtac
    17281 cccagcacat cattcaacgc gggcatgatg gcgccgagtg cttttacgct ccagccgatt
    17341 accgtagtta tctggtgcaa ctgctgcacg ccagcagtcg ctggcaatgc ctggtgcatg
    17401 cttatgtgct gatgcccaat cacgtgcatc tactggtgac gccgtcgtgc gtcggcgcgt
    17461 tggcgcacat gatgcagggg ctcgggcgca actacgtaag ctatttcaat tcgacttacc
    17521 accgttcagg aacattgtgg gaaggacgct acaaatcctg cctggtcggc tcggattatg
    17581 tgctgagctg tcagtgctat atcgaactca accccgtgcg ttcgggattg gtgggcgagc
    17641 catcctcgta cccgtggtcc agctatgcct gcaacgcgtt gggaaaacct gatccggtgg
    17701 tcgttccgca tgccgaattc gtagcgttgg gaaactatag agagcagtgc atgcgcgcct
    17761 atcggcagtt gtttgcggcg gatatcgagc cggctgtgct gagggaaatc cgcacctaca
    17821 ttcagcagca gcgcgcactg ggttcgccgg cgtttcagga gcgggtggaa gcgatgctcg
    17881 gaaggtgtgc aaaggcccgg ccggcgcacc ggccgcgcaa gcgtcccgag gcgatcgggc
    17941 gcgtgtaatg cagcaaggcg cttgatcggt gctgctggcg cagcagcggc gcgatgggct
    18001 atttttccag catcgctttc aaccgcagca gcgcctggtc ccattgctgc gcaatggcat
    18061 cgagcgaacg ccgagcctcc tccagtcgtg atggttcgaa ttcccacaag cgctcgcgcc
    18121 cctgccgtag gtcgcgtacc agcccggcgt ccgccaaaac ctgcaaatgc ttggtaacgg
    18181 cttgccgcgt gatctcggta ccggccgtaa gctgggcgat cgacagcgca ctgccagtgc
    18241 agagcagggc gatcaggcgc aggcgggttt cgtcccccag cgcggcgaac acgggtacag
    18301 ccttgtgcaa cagcggaagc ttggtgcctg cgtttcgcac cgaagcttca gtgcgaggcg
    18361 acataggcgt cgatgttgtt catctgctcc tcccagccgc tgttgttcat gcggaaggct
    18421 tcctgccttc ggtgtgccgg gatccggtcg aatccggatt cgaccacgcg cagcaaggtg
    18481 ccgccggagc tttcctccag ctcgaacgtc accagggtgg tgggttcttg cgaatagtcc
    18541 acatcgggat ctatggcgta cggatgccag cgaaacgaca gcaagcgttc cggttccacg
    18601 cgatcgacca ccaccttcat caccaggtgt tcatagcctg gataggtgat gtttccttcg
    18661 cacggttcgc cggccacgaa gcgctttccc ttgagcgcca cgccgaacca ttcgccaaag
    18721 gattcggcat ccgccagcgc ttgccacacc tttgcacgtg gtgccttgat gaggacctgt
    18781 cgttcgatac gatctgtgga tgagttcata ggcaacctcc tggttgcata ttagtgcggt
    18841 cgtcgctatc catgcaacct catggttgca cttgggcgat cgtgccggcg gcgggcggac
    18901 tggctatgct cgacttgctt ttgtccgatc cgccgcagct cgtacgtcat cggagtggcg
    18961 gcgcatgctg cccgcctcga accgacggag aaatgccatg caatacctac taatgttgtt
    19021 tgccgaagaa aaggcctggg gccggatgtc cagcgcagac caggaacgcg gtgtggccgc
    19081 ctacggcgcc tatacgcagg cactcaagga ggccggcgtg tgggtgggct ccaaccggct
    19141 gcagaacacg gattcggcta ccaccgtgcg cgtggtcgac ggcaagtcgc aggtgctgga
    19201 tgggccctat gcggattcca aggagcagct tgccggctat tacctgatcg aggcggccga
    19261 tctcgacgca gcactgggct gggcagcgcg ctgcccgggc gctggccacg gcaccattga
    19321 agtgcgaccg gtatggccta cgtacggagg cagcccatcg tgagcgaagg cgcttgcgcg
    19381 cgagcggccg cgaacgcggt agcgcgccgc agctatggca agctgctggc gtatctggcc
    19441 gccgacatgc atgacgtgtc ggcggcggag gacgccttgt cggaggcgtt tgctgccgca
    19501 ctggcggatt ggccgctgca tggctgcccc gaccatccgg agtcctggct gatgacggtg
    19561 gcgcgccgca agggcatcga tggtgtacgg cggcgccgca gcggcgaagc tgcttcggtg
    19621 cagttgcagg cgatagccga tatgcgggcg gagtgcgtgg acagcggcga ggaagaggct
    19681 ttccccgatc ggcgcctggc cctgctgttc gcctgcgccc atccagccat cgatgtgggc
    19741 attcgtgcac cgttgatgct gcagaccgtg ctgggcatgg atgcgaagac catcgcctcg
    19801 gcttttctgg tttcgcccga agcgatgggc aaacggctgg ctcgtgccaa gcagaagatc
    19861 cgcgaggcgg gcattccctt tgtcatccct gaacgggacg cctggaacga acggctcgaa
    19921 ggcgtgctca ctgcgatcta cgcgacctat gccgagggct ggagcgatcc tggcgatgcc
    19981 gatctcatgc gccgtgacct ggccgacgaa gcgctcttcc ttgcccgact gctggcggag
    20041 ctgttgccgc aggagccgga aacgctgggc ttgcttgctt gcatgctgta caccgaggcg
    20101 cgccgcggcg cgcgccgtaa cgcgcaaggt gagtacgtgc cattggcgga gcaggacaca
    20161 cttctatggg aggccggcat gatcgatgag gccgaagccc tgttgcggcg ggcaagtgca
    20221 ttccggcgta tcggccgcta ccaactcgaa gcggcgctgc agtcggcaca cgtcgagcgc
    20281 cgccgttccg ggcgtaacga ctggactccc gaggtacagc tttacgacgc gttgcatgca
    20341 ttgaccggct cgccagtcgt tgcactcaat cgcgcgctgg cggtggcgga gcttgaaggg
    20401 cctgaggcag ccattgccat catccgcagc ttgtccgaag acaggcggat ggccgactat
    20461 cagtcgtatt gggccgcgcg tgcggcgttg tttgcgcgtg ttggggatgt gcgcgaagcc
    20521 ttacatgcct acgatatggc gattggtttg gcgcgtgatc cggcggtgcg gcatttttta
    20581 cagcggcagc agagcattct tgagacgaaa tgattgattt gagatccgcg taggctggga
    20641 tgacaatccc agcttacgcg gcttgctgat gccgggtttg ccatcccagc ctacgcgagc
    20701 catctgcccc gccgcgtccc cagtctggca gaatcggtca ttccgcttac cgggaagcca
    20761 agcacatgcg tgacgccgtc actactccgg ccaattcacc cggccgggtc ctgttcgcca
    20821 gcctgatcgg caccaccatc gagttcttcg atttctacat ctacgccacg gcggcggtgc
    20881 tggtgtttcc caagctgttc tttccggcgg gcgatgcgac gacggcaacc ttgcaatcct
    20941 tcgccacgtt cgcactggcc ttcatcgcgc ggccgatcgg ttcggccctg ttcggccact
    21001 tcggcgatcg catcggccgc aaggcgacgc tggtggcggc tttgctcacc atgggcatct
    21061 ccacggtgat gatcggcgtg ctgcccacct acgaccatat cggcctgcta gcaccggcac
    21121 tgctggcgtt gtgccggctg gggcagggcc ttgggctcgg cggcgaatgg ggcggcgccg
    21181 tgctgctggc gattgagaac gcgccgcccg gcaagcgcgc ctggtacggc atgttcccgc
    21241 aactcggcgc gccgcttggt tttctcgccg caaccggtct gtttctgtgg ctccaaaaga
    21301 tgggcgatgg catgttcttc gcctggggct ggcgagtacc gtttctggcc agctcggcgc
    21361 tggtgctgat cggcttgtgg atgcgactgc gcctgaacga aacgcctgcg ttcgcgcgtg
    21421 cgatggcgct gcaggagcgg gtgaaggtac cgatgttcaa cgtgttcgcg cgtcatacgc
    21481 gcgcgctcat cagcggtacg ttcgcggcaa tggccacctt cgtgatcttt tacctgatga
    21541 cggtgttcgc gctgagctgg gcgacgtcca agctcgctta ttcgcgcgaa tcgttcctgg
    21601 tcgcgcaaat ggtgggggta ctgttcttcg ccttgttgat cccattctcg gcttggctgg
    21661 cggacaaacg cagcggccgc ttcgcgatgc tgatggccac agtactgatc ttcgtgttcg
    21721 gcattgccta tgcgccgctg ttcgcgcaga gcggcatgct gttcatggtg gtgggcatgt
    21781 gcgtcgtcgg tctcacctac ggtccgctgg gcacggtact ggcgcagatg ttccccaccg
    21841 ccgtgcgcta taccggtgcg tcgttggcat tcaacatggc gggtattttc ggcgcttcgc
    21901 tcgcgccgta tctggccacc tggctggcca agacctatgg cctggcctac gtgggctact
    21961 atctttcggc ggcggccgtg ctcagtttgc tc
//
