LOCUS       NZ_RYYV01000002        22868 bp    DNA     linear   CON 06-MAY-2024
DEFINITION  Dyella choica strain 4 M-K27 scaffold2, whole genome shotgun
            sequence.
ACCESSION   NZ_RYYV01000002
VERSION     NZ_RYYV01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dyella choica
  ORGANISM  Dyella choica
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Rhodanobacteraceae; Dyella.
REFERENCE   1  (bases 1 to 453784)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Dyella dinghuensis sp. nov. DHOA06 and Dyella choica sp. nov.
            4M-K27, isolated from forest soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 453784)
  AUTHORS   Qiu,L.-H. and Gao,Z.-H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-DEC-2018) School of Life Sciences, Sun Yat-sen
            University, No. 135, Xinggang West Road, Guangzhou, Guangdong
            510275, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina Hiseq 4000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003977665.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 01:53:55
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,733
            CDSs (total)                      :: 4,678
            Genes (coding)                    :: 4,648
            CDSs (with protein)               :: 4,648
            Genes (RNA)                       :: 55
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 48
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 30
            CDSs (without protein)            :: 30
            Pseudo Genes (ambiguous residues) :: 0 of 30
            Pseudo Genes (frameshifted)       :: 9 of 30
            Pseudo Genes (incomplete)         :: 25 of 30
            Pseudo Genes (internal stop)      :: 5 of 30
            Pseudo Genes (multiple problems)  :: 9 of 30
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:37:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 160885
            Orig. end                         :: 183753
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RYYV01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22868
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22868
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22868
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12868](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12868)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            765..1505
                     /locus_tag="EKH80_RS03415"
                     /old_locus_tag="EKH80_03415"
     CDS             765..1505
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-180). E-value: 1.9e-15. Score:
                     49.2. Matches aSDomain:
                     nrpspksdomains_EKH80_RS03415_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="EKH80_RS03415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03415"
                     /product="3-oxoacyl-ACP reductase family protein"
                     /protein_id="WP_126683322.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-38, bitscore:
                     127.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 9.7e-31, bitscore:
                     102.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLTNKTALVTGASRGIGAAIAKRLAADGASVAITYSKGAAAAA
                     QVVKDIEGAGGKAIAIQADATDAKAVNAAVEQVAKTFGRLDILVNNAGTAIPKPFEEAT
                     LDELDTVIDINLRGVFIATQAALKHLPDGSRIINIGSCVGERNMTPGLAAYAATKGAVK
                     MFTQGLSREVGSRGITVNNIQPGPIDTDLNPAEGDWATPQIANTALKRYGQVADVAAMV
                     AFVAGPEAGYITGASLTVDGGTNA"
     aSDomain        786..1304
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS03415_PKS_KR.1"
                     /evalue="1.90E-15"
                     /label="EKH80_RS03415_PKS_KR.1"
                     /locus_tag="EKH80_RS03415"
                     /protein_end="180"
                     /protein_start="7"
                     /score="49.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASRGIGAAIAKRLAADGASVAITYSKGAAAAAQVVKDIE
                     GAGGKAIAIQADATDAKAVNAAVEQVAKTFGRLDILVNNAGTAIPKPFEEATLDELDTV
                     IDINLRGVFIATQAALKHLPDGSRIINIGSCVGERNMTPGLAAYAATKGAVKMFTQGLS
                     REVGSRGITV"
     CDS_motif       792..857
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS03415_0001"
                     /evalue="2.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH80_RS03415"
                     /protein_end="31"
                     /protein_start="9"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LVTGASRGIGAAIAKRLAADGA"
     gene            1601..1999
                     /locus_tag="EKH80_RS03420"
                     /old_locus_tag="EKH80_03420"
     CDS             1601..1999
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019464714.1"
                     /locus_tag="EKH80_RS03420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03420"
                     /product="DUF427 domain-containing protein"
                     /protein_id="WP_126683323.1"
                     /transl_table=11
                     /translation="MTKNDQTSTRSIKKPGPDHPITIERNTHRVIVKILGQVVADTRHA
                     LTLKEASYPAVQYIPRNDVDMALLKRTDHSTYCPYKGECSYFSIPTGGERAVNAVWTYE
                     HPYEAVALIKDHVAFYPDRVNVIEQLDG"
     gene            2038..2784
                     /locus_tag="EKH80_RS03425"
                     /old_locus_tag="EKH80_03425"
     CDS             2038..2784
                     /NRPS_PKS="Domain: PKS_KR (7-172). E-value: 4.1e-14. Score:
                     44.8. Matches aSDomain:
                     nrpspksdomains_EKH80_RS03425_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="EKH80_RS03425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03425"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_126683324.1"
                     /sec_met_domain="adh_short_C2 (E-value: 2.1e-33, bitscore:
                     110.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLTGKTALVTGASRGIGRAAALALAKSGAQVLVHYRSAQKEAD
                     AVVEDIRKAGGRAEKLGADLSMPNGPHELARQARSIIGDRLDILVANAGVSKAATIEDT
                     TVKDFDQLFAVNVRAPYFLIQQLLPTMCAGSNIIFTSSLVARAAVGDLSAYAATKGAVD
                     TLVKHFAASLGSRGIRVNAVAPGVVQTDMSHFTKTEEGRNVTLGMQALKRLAQPNDIAG
                     AIAFLASDEARWITGDTLQVDGGSKL"
     aSDomain        2059..2553
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS03425_PKS_KR.1"
                     /evalue="4.10E-14"
                     /label="EKH80_RS03425_PKS_KR.1"
                     /locus_tag="EKH80_RS03425"
                     /protein_end="172"
                     /protein_start="7"
                     /score="44.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASRGIGRAAALALAKSGAQVLVHYRSAQKEADAVVEDIR
                     KAGGRAEKLGADLSMPNGPHELARQARSIIGDRLDILVANAGVSKAATIEDTTVKDFDQ
                     LFAVNVRAPYFLIQQLLPTMCAGSNIIFTSSLVARAAVGDLSAYAATKGAVDTLVKHFA
                     AS"
     CDS_motif       2065..2142
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH80_RS03425_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH80_RS03425"
                     /protein_end="35"
                     /protein_start="9"
                     /score="16.4"
                     /tool="antismash"
                     /translation="LVTGASRGIGRAAALALAKSGAQVLV"
     CDS             complement(3072..3230)
                     /gene="allorf_163957_164115"
                     /locus_tag="allorf_163957_164115"
                     /protein_id="allorf_163957_164115"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRRSGAMRKRTSQSEMTQRVGCIWCAEDLRAANRRNYETRLMHCA
                     STRCVKE"
     CDS_motif       complement(3135..3230)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRRSGAMRKRTSQSEMTQRVGCIWCAEDLRAA"
                     /locus_tag="allorf_163957_164115_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3072..3134)
                     /prepeptide="core"
                     /locus_tag="allorf_163957_164115_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="2413.7"
                     /monoisotopic_mass="2412.2"
                     /core_sequence="NRRNYETRLMHCASTRCVKE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRRSGAMRKRTSQSEMTQRVGCIWCAEDLRAA"
                     /leader_location="[3134:3230](-)"
                     /alternative_weights="2431.8"
     gene            3398..4546
                     /locus_tag="EKH80_RS03430"
                     /old_locus_tag="EKH80_03430"
     CDS             3398..4546
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03430"
                     /product="hypothetical protein"
                     /protein_id="WP_126683325.1"
                     /transl_table=11
                     /translation="MAFIGWLLVSTLVEPWISTSATRAVINAPAILITAPISGTVSAQY
                     AQNGQPIAPGQTIAVVKNTTVPRDALTTLLTQRLELQSHLDDVNSRLQADQHMLDYTNT
                     QYGKYQEASLAQLKTSYASMQAQQDAADAKLEALDAKYARAMALERDGAISAANVATAR
                     ADADTARKEADALDMSAKSVSAGIAAAQRGVYVSAGQNSNGQLPQLAQHRADIQNSIKE
                     EQAQIDAMNQQMDHLNQLVTHEQDRVQALSDYAVKAYAPGTAQEVVAPIGTQVAVGATL
                     VRATDCSKTNVVAVFPARMTPRLNIGTELRVRVSETSRARSAHITQLMPKATESLQNSY
                     SAPFPYAEDGSVYALAQWDSPDPADPALRSCTPGRSVMASLR"
     gene            4569..5837
                     /locus_tag="EKH80_RS03435"
                     /old_locus_tag="EKH80_03435"
     CDS             4569..5837
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS03435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03435"
                     /product="hypothetical protein"
                     /protein_id="WP_230473393.1"
                     /transl_table=11
                     /translation="MSTRWRQVASVGLIFTMVASTHANAGTLQQQLAASSCGTLRSAAM
                     AEPGNGPMLLPSYPTLKQGDDATRALENVAFVYDNALAGIALSACGNPDQARRIADALL
                     LAAVHDPSFKDGRLRNAYRSGPAHADKVELPGYWQSHGNYWSQDPYQVGTAVGNVAWAA
                     LLLLSVYDHSHDRRYLDGAVAQLRWIQDHASGAASPPGYEGGFFGYDNAQRAQHWKATE
                     HNIDVYAAATWAGRDSGDPALAQQAKLAAGFVYSMWDDTQHRFLVGTLDDGKTLSHDKS
                     GLDAQLWPLLAFSSPPAEWNQVWSWVDTQHRYGNGYGYRRHPDGIWTEGTAQVATALQA
                     SGKPVPDAVWQLLAAQRSESGMLYATPQRRIGTDFAIGPTSTYADFFYYHLPHLGATAW
                     AALAGMGWNPLTGRPIARTEATP"
     gene            5834..7807
                     /locus_tag="EKH80_RS03440"
                     /old_locus_tag="EKH80_03440"
     CDS             5834..7807
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467336.1"
                     /locus_tag="EKH80_RS03440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03440"
                     /product="glycosyltransferase"
                     /protein_id="WP_126683326.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.4e-27,
                     bitscore: 90.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPVDEMKLLHLLALTVLFGIGMACVANPKRSLHRLVFGTFSGV
                     LLLRYAIWRATETLPDPSHGFASVWSYVFFFFEMVSIVYTLATIVVMVRRRDSRPSADA
                     GEARLRAAGGRVPAVDVFIATYNEDLQILEKTIVSAKAIDYPHVNVWVLDDTRRDWLRD
                     YCARMDVHYVRREDNRHAKAGNLNNGLKLSAQHTNAPYILVLDADFASQKNILYRVLGL
                     FDEPNVALVQTPQFYYNADPIQHNLGATDSWVDEQRVFFDVFQPSRDAWNSAFCVGTSF
                     VISREAITQAGGFPTDSVCEDIHTTYVLRRNGHITRWLNERLSVGLSAEGLIEYINQRG
                     RWCLGTMQVALLKDGPLRGPGYNLVDRLHYIHGMLHWIGKPFLLLMLIAPVLYWYFGIA
                     AFYTTPEQFVFYGVPALVGFWLYGPWITERKTLPIFTEVTQLVAAYAVTMTMISACFKP
                     FGRPFKVTAKGLDRSKVVVHWKLASFFIALMLCLMAGAVNSVMTAQMNGGTAFNLAWTL
                     IALVLDLAAIVACVDLPRLRQEERFPFPRAARWRQGGHVQSSEFIDISLDGAAMSHSPV
                     MPTPGEALEVSVPEVGWVPATVVRLSKRRLCVRFKPNEATRHLLIKLIFCHAPHNIAVK
                     ARPLRAFAQLMRMAGFALFPPR"
     gene            7822..9351
                     /locus_tag="EKH80_RS03445"
                     /old_locus_tag="EKH80_03445"
     CDS             7822..9351
                     /GO_component="GO:0009279 - cell outer membrane [Evidence
                     IEA]"
                     /GO_function="GO:0015288 - porin activity [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1076: RND efflux
                     system, outer membrane lipoprotein,"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR01845.1"
                     /locus_tag="EKH80_RS03445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03445"
                     /product="efflux transporter outer membrane subunit"
                     /protein_id="WP_158628731.1"
                     /transl_table=11
                     /translation="MKPLLCSAALASCMLAGCSMEPTYQRPGMPVPDSFPSTAPITRTA
                     PSTAAAQADAEVANLDWHQFFKDTALQRLIEIALGNNRDLRVAAANMTQARANYGVARA
                     SLFPEIDLQAYGGRQRLPAMSQQPANGLLGPVQNNNDKAATFNTYQVQAGMTSYEVDFF
                     GHQRAIAHESGKLADASAAEYEAARIALIGEVANAYLSLNADRALLQLAQQTLAAQQQH
                     AQVMNKAYGDGGVSEFDMRRSQAQADAAQVDVENLQIRIAKDTNAMAVLIGQPLPAGYS
                     APSQWEDPLLTDVPAGLPSSLLDRRPDIVAAEDRLRAANADIGRARAAFFPNIALTAVL
                     GTLSGGLSSLFHAGSAAWTGAVSGTIPLLDWGKNKNGLAASKAGYTGAVAAYEGTVQEA
                     FREVADTLAVRDHIVPALKAQQALVDQSQRIYSISQVRFKEGLDDYISSQDAQRSLYTD
                     QQKLVSLKLEQAVNQVNLYKALGGGWNPTHSGNTTARVTLPVRQSSVRASL"
     gene            complement(10001..12868)
                     /locus_tag="EKH80_RS03450"
                     /old_locus_tag="EKH80_03450"
     CDS             complement(10001..12868)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="EKH80_RS03450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03450"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_126683328.1"
                     /sec_met_domain="DUF4135 (E-value: 9.4e-75, bitscore:
                     246.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-45, bitscore:
                     149.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSSADAGGFTATLGCLVEPGLVRLAAQLQTIPGLGACERATILQ
                     ATRSSLLSTLHGKLTRLLLLELNAARVTGRLGGEDAQQRWREFCAIAAELSWWEGLAEH
                     YATLSTRIARIVDNRCSAILRFAQRWATDRPALASLCGGKPGDLLELSIGTGDSHCDGQ
                     SVVLLRTEGGRLVYKPHSVAVDAELHDLIEYLATCGSTSSMKVPRVAVYPGYGWAEFVA
                     HRYAADDSELHDFYRGIGHWLALMRVLGGSDLHAENLIAMGPHPVVVDCETLFTPRMPP
                     RPSGWGQAVDQAVEVLGGTVLAIGLLPARGQALGWRGVDSSGIGRLRGQQPMQPQAIIE
                     NVGTDEARLGSIMTELMAAQNQPSEQPALVRFWPRVLEAFDEMTACLRRLDAEGQLQVR
                     LRRFADCPVRVVVRATEIYAEIGRMLWHPISLHDEGAARKRAFDLLAEMAERTALAPSD
                     AAVIEAEIDALMVGDIPFFSTLPRHGRLDGPGRTQWLAPGDRIEEVLQAWRTSDLQLDR
                     QVIQAALVSAFIGEGLLPKQGSLWSVRARQGDIERRRRHQSAAIMRQILANAIRGGDGS
                     IAWIAPVVGPTSRTTQPIKQDLYNGISGIAVAVAAYLRETDAGRANSVDGLDELLSASL
                     RTLDQAETTRLRDEAGDIKIRPRLPGGYVGLGSQIWTCLTLARWGIEQEQMLHRACALA
                     AQLPNAVMEDTTHDVLSGVAGAIPPLLALAAALPVGGYLTMARQFGDLLCERARYQDGL
                     ACWGGESGMAGLGGFSHGATGIGWALRKLARASGESRYDELADAAFAYDDSLFDTEHGN
                     WRDLRTTERALGAATWCNGAVGIGLAHVDLDPELTHPSTRLLLRRAAAATWHFGLGLDH
                     CLCHGDLSVWEMFEHAIAAGEAPKGMSSEHLQASILSSLESHGPTCGMTKDIFVPGLMT
                     GVAGVAYQLLRMHPASQLPSVLTLA"
     gene            complement(13018..13209)
                     /locus_tag="EKH80_RS03455"
                     /old_locus_tag="EKH80_03455"
     CDS             complement(13018..13209)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.3"
                     /locus_tag="EKH80_RS03455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03455"
                     /product="DUF6229 family protein"
                     /protein_id="WP_126683329.1"
                     /transl_table=11
                     /translation="MDTVLEGEALVAQWRASADVDSPAGPLFIGGKYAKADIVNSAESI
                     TTNFLCTCGTAIHDNCCN"
     CDS_motif       complement(13135..13209)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MDTVLEGEALVAQWRASADVDSPAG"
                     /locus_tag="EKH80_RS03455_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13018..13134)
                     /prepeptide="core"
                     /locus_tag="EKH80_RS03455_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.60"
                     /molecular_weight="3898.4"
                     /monoisotopic_mass="3895.9"
                     /core_sequence="PLFIGGKYAKADIVNSAESITTNFLCTCGTAIHDNCCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDTVLEGEALVAQWRASADVDSPAG"
                     /leader_location="[13134:13209](-)"
                     /alternative_weights="3916.4"
                     /alternative_weights="3934.4"
     gene            13443..14030
                     /locus_tag="EKH80_RS24040"
                     /old_locus_tag="EKH80_03460"
     CDS             13443..14030
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03460"
                     /product="hypothetical protein"
                     /protein_id="WP_148110418.1"
                     /transl_table=11
                     /translation="MPWLPIYASRHDQAELFEYLNNSPDLAFIRSDGAGRWRAFEKLES
                     WCDGRYCLWHTESGPLPLLQTWGKAHRVVNDPFEGWVEVRPGADKSQPYFGAGHPGIIW
                     FNAYSSDPRSANVSTIGISSFEWIGNHYQALGNVAAPSTKALWGSLRRWVSKRAVKVPR
                     DGPAQSTPAEIWAMSDALELFSKGIPGAPNPP"
     misc_feature    complement(13486..13500)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.01"
                     /tool="antismash"
     gene            complement(14050..14940)
                     /locus_tag="EKH80_RS03460"
                     /old_locus_tag="EKH80_03465"
     CDS             complement(14050..14940)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS03460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03465"
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="WP_126683330.1"
                     /transl_table=11
                     /translation="MGWTNIDPYPFHVTQWPKSVASYGDYDGGERLQLSWDLGRVSEKE
                     KKQAIKQWVERLPELHNVRWLSLWSHVTPPLLEAACRMTHLECLQIKWSNVRDISSIGN
                     LRHLRYLYFGSSTKIESVEPLAALSNLRLLEIENFKRVTDFSPLARLTSLESLAVTGSM
                     WTRQDIGALETFGQMTWLQSLAIDTSKVKTLRPLANLSGLKFLGVGNRLPMPEYAWLSA
                     MLPNTQCRWFEPYLDLAGTGFSICTQCRQDSKVMLTGKGGKLLCRICDSKQIERHEEAF
                     IVAKSQALAEHPRRS"
     CDS             complement(14958..15026)
                     /gene="allorf_175843_175911"
                     /locus_tag="allorf_175843_175911"
                     /protein_id="allorf_175843_175911"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSPQNALGQAAMARAYTCLRGT"
     CDS_motif       complement(14982..15026)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSPQNALGQAAMARA"
                     /locus_tag="allorf_175843_175911_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14958..14981)
                     /prepeptide="core"
                     /locus_tag="allorf_175843_175911_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.90"
                     /molecular_weight="776.9"
                     /monoisotopic_mass="776.4"
                     /core_sequence="YTCLRGT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSPQNALGQAAMARA"
                     /leader_location="[14981:15026](-)"
                     /alternative_weights="794.9"
     gene            15107..15580
                     /locus_tag="EKH80_RS03465"
                     /old_locus_tag="EKH80_03470"
     CDS             15107..15580
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="EKH80_RS03465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03470"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_126683331.1"
                     /transl_table=11
                     /translation="MNRNTPQTLDTVSSIVSEVTAHCLMTRTRRISRVVTSLFDQELRP
                     YGLSSSQFSLLVLIARMDGASRAEIGRANHQERSTSTRNLQLVIDQGWAEELVPEKGRS
                     RPIVISKAGRTLLAQAIPAWRAAQVKAKQLLGADGASAIVRLSSGLPIEELAG"
     misc_feature    complement(15584..15597)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            15635..16609
                     /locus_tag="EKH80_RS03470"
                     /old_locus_tag="EKH80_03475"
     CDS             15635..16609
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012993.4"
                     /locus_tag="EKH80_RS03470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03475"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_126683332.1"
                     /transl_table=11
                     /translation="MTIVKAAAVQISPVLYSREATVEKIVRKIHDLGQRGVQFATFPET
                     VVPYYPYFSAVQTPMAQLFGSEYLRLLEQSVTVPSPTTDAIGEAARKAGMVVSIGVNER
                     DGGTIYNTQLLFDADGTLIQRRRKITPTHFERMIWGQGDGSGLRAVDSKVGRIGQLACF
                     EHNNPLARYALMADGEQIHSAMYPGSAFGDGFAMRMEINIRQHALESGAFVVNATAWLD
                     ADQQAQIMQDTGCQIGPISGGCFTAIVAPDGTLLGEPLRAGEGEVIADLDFDLIYRRKQ
                     QMDSRGHYARPELLSLLIDRTPTAHLHDRAARSAIDLARAEIL"
     gene            16628..17548
                     /locus_tag="EKH80_RS03475"
                     /old_locus_tag="EKH80_03480"
     CDS             16628..17548
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF017206.4"
                     /locus_tag="EKH80_RS03475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03480"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_126683333.1"
                     /transl_table=11
                     /translation="MNTSNESPILVTGAAGDVGAVGRSVVAMLLEKGHKVRALVRREDE
                     RSESLRKLGADVVVGDLTDLKSVHRAIEGCQRIYFGMSISAAYLEATANVAAVARHHGV
                     EVIVNMSQMTVSQMGIHETTDSPQHKLHWLAEQVLAWSGLPVVNVRPTVFLDGFFLRLA
                     AMGVRDNDELVLPLGGAKTSPIAAYDVARVVATILDDPAPHIGQIYNLTGPESVDVEQH
                     ARAFSEALGRTIRYRDVPVEPWAEKLREFGVPPHLLSHLAAMARLHAQGRYDRATDDVF
                     KLTSQKAMSTAEFVKRHAAEFTRGQ"
     gene            17660..18682
                     /locus_tag="EKH80_RS03480"
                     /old_locus_tag="EKH80_03485"
     CDS             17660..18682
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (71-229). E-value:
                     3.1e-29. Score: 94.2. Matches aSDomain:
                     nrpspksdomains_EKH80_RS03480_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="EKH80_RS03480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03485"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_126683334.1"
                     /sec_met_domain="PF00561 (E-value: 8.4e-25, bitscore: 82.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3e-19, bitscore:
                     64.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKCLSLFSSIAMALAVSVSATHAAEVLPSGAAHATGKVSDAALVK
                     SLPGFKNAYTDVDGVRLHYVTGGKGEPLVLLPGWPETWWTFHKIMPALAEHYTVIVIDI
                     RGMGTSSRPTDGYDKKTMAKDIYALVQSLGYDKVAIAGHDIGSAVAYAYAENYPQATDK
                     LVMMEFPHPDESLLTFPLLPTQGPVGDKVGSSRPYLWWFAFNQVNELPEKLLAGRIRVE
                     QDWLFKYFLQDENAIDARDRAVYEQAYNSGEAIRAGNAWYQAFGQDVADNKGYGKLEMP
                     VLVLAGPAYPWMKAVVGKKATKLIALPVPNSGHFVQEEQPDFVSKTMIDFLQNPDTSNR
                     "
     aSDomain        17873..18346
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH80_RS03480_Abhydrolase_1.1"
                     /evalue="3.10E-29"
                     /label="EKH80_RS03480_Abhydrolase_1.1"
                     /locus_tag="EKH80_RS03480"
                     /protein_end="229"
                     /protein_start="71"
                     /score="94.2"
                     /tool="antismash"
                     /translation="PLVLLPGWPETWWTFHKIMPALAEHYTVIVIDIRGMGTSSRPTDG
                     YDKKTMAKDIYALVQSLGYDKVAIAGHDIGSAVAYAYAENYPQATDKLVMMEFPHPDES
                     LLTFPLLPTQGPVGDKVGSSRPYLWWFAFNQVNELPEKLLAGRIRVEQDWLFKY"
     gene            18887..19348
                     /locus_tag="EKH80_RS03485"
                     /old_locus_tag="EKH80_03490"
     CDS             18887..19348
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039665.3"
                     /locus_tag="EKH80_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03490"
                     /product="DUF6130 family protein"
                     /protein_id="WP_126683335.1"
                     /transl_table=11
                     /translation="MSFTLRSLFIVAFGSLFCTAAWGQNTAEGDHPPALLPLASEPAPK
                     IVAYAPLAEPLARGVAIIPFRTENLRIMPVFGTAAAQVSPRLGHLHVTVDHWPGGWAHT
                     SVDPVIVNALAPGPHKVLLEIADPTHKIMTSTTVDFVAPQRKADEQHAH"
     gene            19389..19829
                     /locus_tag="EKH80_RS03490"
                     /old_locus_tag="EKH80_03495"
     CDS             19389..19829
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03495"
                     /product="hypothetical protein"
                     /protein_id="WP_126683336.1"
                     /transl_table=11
                     /translation="MKFTETAPTLPCPSGPPPWLGKIAQDATLEGAVLKRAVHGKDNIL
                     ALISHARSLYEFQDYTYYGPWGSEFFMESYRASINGVPMECSVIVHMNDAGEADSLLIH
                     HYPLDATLEFSRLMGEKFGDQFANLYLTAAQADGLAKASSKK"
     gene            complement(19927..20316)
                     /locus_tag="EKH80_RS03495"
                     /old_locus_tag="EKH80_03500"
     CDS             complement(19927..20316)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024093.4"
                     /locus_tag="EKH80_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03500"
                     /product="VOC family protein"
                     /protein_id="WP_126683337.1"
                     /transl_table=11
                     /translation="MSVPSAIEVVTLFVDDITQAMTFYESVFQSKVMGRDEVSCLLDFG
                     GIAVNLLQRSEAPELIEPLPVAPATAGSHVLLTIKVTDVDATCAMLQDRGVRLLNGPVD
                     RPWGRRTAAFADPSGHVWEVAQELG"
     gene            complement(20366..20962)
                     /locus_tag="EKH80_RS03500"
                     /old_locus_tag="EKH80_03505"
     CDS             complement(20366..20962)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018684.4"
                     /locus_tag="EKH80_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH80_03505"
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="WP_230473394.1"
                     /transl_table=11
                     /translation="MTSLRCWPEADRGRVTGADYDGAAYIEFNPDTSSVVPSHSLENFS
                     ENSSVSANLSSTSVRETQRIATMFRKSSLVFSATLCIAAFTASAQESAQFSKCLDQAAG
                     ASGKMLECHKTEVGRWDPRLNAAYQTLLHRYKDKQRAQLQQEQRAWLKHHLSETHRLAA
                     QPEDIGDAAFLQSESFELDDLITRTLALEKLVNQK"
     gene            20988..22568
                     /locus_tag="EKH80_RS03505"
                     /old_locus_tag="EKH80_03510"
     CDS             20988..22568
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH80_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH80_03510"
                     /product="hypothetical protein"
                     /protein_id="WP_126683338.1"
                     /transl_table=11
                     /translation="MRTTEAPQSAARGESVAWRKPGEVAESPLQAMIDQSPRMTAQRRM
                     IADIRSGTAPRQLAQLNAAPDSEGTGIPGAASEQSMLEQDPDTRKEQAREDLLATIDDL
                     DGADGQQLERVLAQLQEKYALSKTVVDVDDPENLKVELYASPPLVIAGAALGIVAIATM
                     GAAYASYTLRRRVTYHRTIRRLTTAGYRRDDAEALFRQHNNERDLIDWAPVLRRQIEDR
                     VAIDEAMIAGMQIYDRSVTRLVTAGYRRHDAEALFRLHGHVDHLIAWAPILRRQIEDGV
                     AIDQEMLTNVLRQHGAADKMEELQRAGDGKNLAWGEHNPGLNLNEPGHLTELGRWINDK
                     NNNPEPDPVRGTMNCWEVIWFSAYKMRYITWEHMHEVYQNELEGTSLNTYFNERIRVGA
                     QKKFDPNNADSGRPLRGDIVLFGSAEVHTAMATGTEAGPEGKRSPEVFSLWTQPNHNYL
                     QRVTINALLAVDSEWDDDDEEEENEEEEEKKEEEVKSDKSELRISIRRGKDKAAGHGPP
                     VWFFSPKWG"
     CDS             22598..22783
                     /gene="allorf_183483_183668"
                     /locus_tag="allorf_183483_183668"
                     /protein_id="allorf_183483_183668"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMLGVIRPSSLLHRRGEGRFSHGGCMSQAMQPSTKCRNSTRAKGP
                     LGFAPNGVFLSVHLDA"
     CDS_motif       22598..22669
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMLGVIRPSSLLHRRGEGRFSHGG"
                     /locus_tag="allorf_183483_183668_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22670..22783
                     /prepeptide="core"
                     /locus_tag="allorf_183483_183668_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.00"
                     /molecular_weight="3813.4"
                     /monoisotopic_mass="3810.9"
                     /core_sequence="CMSQAMQPSTKCRNSTRAKGPLGFAPNGVFLSVHLDA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMLGVIRPSSLLHRRGEGRFSHGG"
                     /leader_location="[22597:22669](+)"
                     /alternative_weights="3831.4"
                     /alternative_weights="3849.4"
                     /alternative_weights="3867.4"
                     /alternative_weights="3885.5"
     CDS             22776..22859
                     /gene="allorf_183661_183744"
                     /locus_tag="allorf_183661_183744"
                     /protein_id="allorf_183661_183744"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLDVIPVGGQVDGASKRATRLSTCHSG"
     CDS_motif       22776..22799
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLDVIPVG"
                     /locus_tag="allorf_183661_183744_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       22800..22859
                     /prepeptide="core"
                     /locus_tag="allorf_183661_183744_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="1841.0"
                     /monoisotopic_mass="1839.9"
                     /core_sequence="GQVDGASKRATRLSTCHSG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLDVIPVG"
                     /leader_location="[22775:22799](+)"
                     /alternative_weights="1859.0"
                     /alternative_weights="1877.0"
                     /alternative_weights="1895.1"
                     /alternative_weights="1913.1"
ORIGIN
        1 cccgcgaggt gattctcttc aacaacgccg gcgtctcctc gagctccggc gaagttcctc
       61 ccagcttccc ggaaatgggc ggcaatgcca tcgccttcat caaggcgctc ggtctttcca
      121 aagttgacgt gctgggcttc tccatcggcg gcatggtggc ccaggaaatc gctgtgcagg
      181 gcggcgatct gatccgcagg gtgatcctgg tcggcaccgg tccgcgcggg gccgatatgg
      241 ccgccagcca gtcgcatgcg atcttttcag gcacctacga tccgcctgag cagctgtggc
      301 tggccgttca cttctcgccc tcggcctcca gccgcgaagc gggtctggcc ttcctcaagc
      361 gcaaatggga acgccaggat cgtgatccgg aaatgagtgc cgaagccatc gctcgccaag
      421 gtgaggccat cggcaagtac atcgcccagc acgaaggcgt gcttgactat ctgaagggca
      481 tccgccagcc caccctcgtc gtgcagggca gcgatgatgt gatcatcccg acgcacaact
      541 cctacgtctt gcaacagaac ctgcccaacg cccagctgat catctacccg gacgccaatc
      601 acggctcctt ctaccaatac ccggagctgt tcgtggcaca agccacacag ttcctcgacg
      661 caggattcaa gacgcccgac ggtgtgtccg gaaacctgcc gttccctgcc cttccgtcgt
      721 ccaactgaac cctcttactt cactactttg aaggaataac tctcatggca aacctgacca
      781 acaagacagc actcgtaacc ggcgcctctc gcggcattgg cgcggccatc gccaagcggc
      841 tggccgccga tggtgccagc gtggcaatca cctatagcaa gggcgccgct gccgctgccc
      901 aggtggtgaa agacatcgaa ggagccggcg gcaaagccat cgcgatccaa gcggacgcaa
      961 ccgatgccaa ggctgtcaac gccgcggtgg aacaggttgc gaaaaccttc ggccgactcg
     1021 acattctggt caacaacgcg ggcaccgcca tccccaagcc gttcgaagaa gccaccctgg
     1081 atgagctgga cacggtgatc gatatcaatc tgcgcggcgt gttcatcgcc acgcaggccg
     1141 cgctcaagca cctgccggat ggcagtcgca tcatcaatat cggctcctgc gttggcgagc
     1201 ggaatatgac gccgggtctg gcggcttacg ccgcaaccaa aggcgcggtg aaaatgttca
     1261 cgcaaggact gtcgcgcgag gtcgggtccc gcggcatcac ggtcaacaat atccagcccg
     1321 gccccatcga caccgacctg aatcccgccg aaggcgattg ggcaacaccg cagatcgcca
     1381 acaccgcgct gaagcgctac ggacaggttg cggacgtcgc cgcgatggtg gccttcgtcg
     1441 ccggccccga ggcgggctat atcactggcg cgagcctgac ggttgacggc ggtaccaacg
     1501 cctgagaacg catgagggta gcccattgca agaacctctc gcgcctcttt ttagaggcgc
     1561 gtaaaccgga cgagcaatcg tcctcccaag gagatctcac gtgaccaaga atgaccagac
     1621 ttccaccaga tcgatcaaga aacctggacc ggatcacccc atcacgatcg aacgcaatac
     1681 acatcgcgtt atcgtaaaaa tccttgggca ggtcgtcgcg gatacgcgtc atgccctcac
     1741 gttgaaagaa gccagttatc cagcagtgca gtacattcca cgcaacgatg tggatatggc
     1801 actgctgaaa cgcactgatc acagcactta ctgcccgtac aagggcgagt gctcctactt
     1861 cagcattccg acgggtggtg aacgcgccgt caatgcggtg tggacgtacg agcatcccta
     1921 cgaagctgtt gcgcttatca aggaccacgt cgcgttctat cccgatcgcg tcaatgtcat
     1981 cgaacagctt gacggctgat tccgccatcc gacctcccct acgaacggag aaatgtcatg
     2041 agcaatctca cgggtaaaac ggcgctggtg accggcgcct cacgcggtat cggtcgggcc
     2101 gccgcgcttg ccctggccaa atccggcgcc caggttctgg tccattaccg cagtgcgcag
     2161 aaggaagccg atgccgtcgt ggaagatatc cgtaaagccg gcggtcgtgc cgagaaacta
     2221 ggtgccgatc taagcatgcc gaacggtccg catgaattgg ccagacaggc tcgcagcatc
     2281 atcggcgacc gattggatat cctcgtggcc aacgctggcg tctcaaaggc agcgaccatc
     2341 gaagacacca cggtcaagga cttcgaccag ctctttgccg tgaacgtgcg tgcgccgtat
     2401 ttcctgatcc agcaactgct gccgaccatg tgtgcgggca gcaacatcat ctttacctct
     2461 tcgctcgttg cgcgcgctgc ggtaggcgac ctatccgctt atgcggcgac caaaggcgcc
     2521 gtcgacacgt tggtcaagca tttcgcagca tcgctgggct cccgcggtat ccgcgtcaac
     2581 gccgtcgcgc caggggtggt gcagacggat atgtcccatt tcaccaagac tgaagaaggc
     2641 cggaatgtga cactgggcat gcaggcgctc aagcgcctcg cacagcccaa cgatatcgcc
     2701 ggcgccattg cgtttcttgc ctcggacgag gcgcgctgga ttaccggtga caccctgcaa
     2761 gtggatggtg gttcgaagct gtagcaaaag gcgtgccttg gctgactggc tgttgattac
     2821 ctgcgtgaaa cggacgatgt gtaagagtcg caactcctac tagtgtgtcg acgggcttgt
     2881 gatcgccgaa cagcgtcacc cgagtcgctt cgttaaggtg ctgcgtcgcg acatctgcgt
     2941 gtcaagcgac tgtcggcaat aagtcgagta atcgcagcca ttgcgttaaa attgtccttc
     3001 tctcgaactc aaatctaact gatccatggc gtgcgagcgg atcaagtcag acgacgttca
     3061 ttcgcgttca actattcctt tacgcatctg gtgctggcgc agtgcatcaa tcgagtttcg
     3121 taattcctgc gattcgcagc acgtaagtcc tctgcgcacc agatacagcc aactcgctgt
     3181 gtcatctcgg attgagatgt tcgctttctc atcgctccgc ttcggcgcac aggcgtgggc
     3241 gtctgtgcga cttcaatgac agagacgaac cattttgaaa actcagttga ttccccgtga
     3301 acccctacac cgacctaccg cgttaccacc cagcaagatc aagccagaca agaagtcatc
     3361 gttcgccctt gtgcctcgcc tcgccggcta cgcactcatg gccttcattg gctggctgct
     3421 ggtgtcgacg ctggttgagc cctggatttc caccagtgcc acgcgcgccg tcataaacgc
     3481 accagccatt ctgatcaccg cgccgatcag cggcacggta agcgcccaat acgcgcaaaa
     3541 tggacaaccc attgcgccag gacaaaccat cgccgtagtg aagaacacca ccgtgccgcg
     3601 tgatgcgcta accacgcttc ttacgcagcg ccttgagctg caaagccatc tggacgacgt
     3661 caatagccgt ctgcaggccg atcaacacat gctcgactac accaacacgc aatatggcaa
     3721 ataccaggag gcaagcttgg cccagctcaa gacctcctac gcgtccatgc aggcccagca
     3781 ggatgcggca gacgccaaac tggaagcgct cgatgccaaa tatgcacgcg ccatggcact
     3841 ggaacgtgac ggcgccatca gcgcggccaa cgtagccacc gcgcgcgcgg atgccgatac
     3901 cgcgcgcaag gaagccgacg cattggatat gagcgccaag agcgtcagcg caggcatcgc
     3961 cgccgcgcaa cgcggcgtgt atgtctccgc cgggcagaac agcaatggcc agttgccgca
     4021 actggcgcag caccgcgccg atattcaaaa cagcatcaag gaagagcaag cgcagatcga
     4081 tgcgatgaac cagcagatgg accatctcaa ccaattggtc acgcatgagc aggatcgtgt
     4141 gcaggcgctc tctgactatg cggtcaaagc ctatgcgccc ggcacggcac aggaagtggt
     4201 cgccccgatc ggcacgcaag tggccgtagg agcgaccttg gttcgtgcca ccgactgcag
     4261 caagaccaat gtcgtggcgg tattccctgc gcgcatgacg ccacgcctga atatcggcac
     4321 cgagctgcgc gtacgtgtca gcgaaaccag tcgcgcacgc agtgcgcaca tcacgcagct
     4381 gatgccaaag gccaccgagt ccctgcaaaa cagctacagc gcgcccttcc cctatgccga
     4441 agatggttct gtctacgcac tcgcacaatg ggatagcccg gaccccgccg acccagcact
     4501 gcgatcctgc acgcctggtc gcagcgtgat ggcaagcttg cgttgatctc gtgccgaagg
     4561 agtctcctat gtctacgcga tggcgtcagg ttgcaagcgt cggcctgatc ttcacgatgg
     4621 ttgcatccac gcatgcaaac gccggcactt tacaacagca gctcgctgcc agcagttgtg
     4681 gcaccttgcg ctcggcggcg atggcggaac ctggcaacgg acctatgctg ttgccgagct
     4741 accccacctt gaaacaaggc gatgacgcga cccgggcgct ggaaaacgtg gcattcgtct
     4801 acgacaacgc cttggccggc atcgcgctca gcgcctgcgg aaaccctgat caagcgcgtc
     4861 gcatcgccga tgccctattg ctcgccgctg tgcatgatcc cagcttcaag gacggtcggc
     4921 tacgcaatgc ctaccgatca ggtccggccc atgccgacaa ggttgagctg cctggctact
     4981 ggcagagtca tggcaactac tggagccagg acccgtatca ggtcggcacc gccgtaggta
     5041 atgtcgcgtg ggccgcgttg ctgctgctga gcgtctacga tcacagtcac gatcgtcgtt
     5101 atctggatgg cgccgtggcg cagcttcgct ggatccagga tcacgcttca ggcgccgcat
     5161 cgccaccggg ctatgagggc ggcttcttcg gttacgacaa tgctcagcgc gcccagcact
     5221 ggaaagccac cgaacacaat atcgacgtct atgccgccgc cacctgggcc ggccgcgaca
     5281 gcggcgaccc ggcgctcgcg caacaggcga aactggcagc tggcttcgtc tattcgatgt
     5341 gggacgacac gcagcatcgt tttcttgtgg gcaccctgga cgatgggaag acgctttccc
     5401 acgacaaatc cgggctggac gcccagctct ggccactgct ggcgttcagt tcgccgccgg
     5461 ccgaatggaa ccaggtgtgg tcatgggtcg atacgcagca tcgctacggc aatggctacg
     5521 gctatcgccg tcatcccgat gggatctgga ccgaaggcac ggcgcaggtc gccaccgcgc
     5581 tgcaagccag cggcaagccg gtgcccgacg ccgtctggca gttgctcgcg gcacaacgca
     5641 gcgagagcgg catgctctac gccacgccgc agcggaggat cggcactgac ttcgcgattg
     5701 gccccacgtc gacgtatgcc gacttcttct actaccacct gccgcacttg ggcgcgactg
     5761 cctgggctgc attggcaggc atgggctgga atccactcac cggtcgcccg atcgcgcgca
     5821 cggaggccac gccatgaccc tgcccgtcga tgagatgaag ctgctgcatt tactcgcgct
     5881 gaccgtgctg ttcggtatcg gcatggcgtg cgtggccaat ccgaaacggt cgctccatcg
     5941 ccttgtgttc ggtacattct cgggcgtcct gctactgcgc tatgccatct ggcgcgccac
     6001 tgaaactctg cctgatccca gtcacggctt tgccagcgtg tggtcttacg ttttcttctt
     6061 cttcgagatg gtttccatcg tctacacgct tgccaccatc gtggtgatgg tgcgtcgtcg
     6121 cgattcgcgc ccatccgccg atgccggcga agcgaggctg cgcgccgcgg gtggccgcgt
     6181 ccccgcggtc gatgtattca ttgccaccta caacgaagac ctgcagatcc tcgagaaaac
     6241 catcgtctcg gcgaaagcca tcgactatcc acatgtcaac gtctgggtgc tggacgatac
     6301 ccgtcgcgac tggctgcgcg attactgtgc gcggatggac gtgcactacg tgaggcgcga
     6361 ggacaaccgc cacgccaagg caggcaatct caacaacggg cttaaactgt ccgcgcagca
     6421 cacgaacgcg ccctacattc ttgtgctgga cgccgatttc gcgtcgcaga aaaacattct
     6481 ttaccgcgta ctcggcctgt tcgacgagcc caacgtagcc ttggtacaga cgccgcagtt
     6541 ctactacaac gccgacccga tccagcacaa cctgggtgcg accgacagtt gggtggacga
     6601 acaacgcgta ttcttcgacg ttttccaacc atcacgcgat gcgtggaact cagccttttg
     6661 tgtgggaact tcgttcgtga tatcgcgcga ggcgatcacc caggccggcg gcttccctac
     6721 cgacagcgta tgtgaagaca tccatacgac ctatgtgttg cgcaggaacg gccacatcac
     6781 ccgctggctc aacgaacgtc tctccgtggg gttgtccgcc gagggcctga ttgagtacat
     6841 caaccagcgc ggccgctggt gcctgggcac gatgcaggtg gccctgttga aggatggccc
     6901 tctgcgcggt cccggctata acctggttga ccggctgcac tatatccacg ggatgctgca
     6961 ctggatcggc aagccattcc tactactgat gctgatagcg ccggtgctgt actggtactt
     7021 cggcatcgct gcgttctaca cgacgccgga gcagttcgtt ttttacggcg tgccagcact
     7081 ggtcggattc tggctctacg gcccgtggat caccgagcga aaaacgctgc cgatcttcac
     7141 cgaggtgacc caattggtgg cggcctatgc cgtgacgatg accatgattt ccgcttgctt
     7201 caagccgttc gggcgcccct tcaaggtcac cgccaagggg cttgatcgca gcaaagtggt
     7261 tgtccactgg aaactggcca gcttcttcat cgcactcatg ctgtgcctga tggcgggcgc
     7321 tgttaatagc gtgatgactg ctcagatgaa tggcggcacc gcgttcaacc tggcatggac
     7381 actgatcgcg ctagtgctgg acttggccgc gatcgtggcg tgcgttgatt tgccgcgatt
     7441 gcggcaagaa gagcgcttcc ccttcccgcg cgccgcgcgc tggcgtcaag gtgggcatgt
     7501 gcaatctagc gagttcatcg atatctcgct cgatggcgcg gccatgagcc acagccccgt
     7561 gatgcccacg ccaggcgaag cgcttgaagt gtccgtacca gaagtcggtt gggtgccggc
     7621 cacggtggtg cgcctcagta aacgccgctt gtgtgtgcgc ttcaagccga atgaggcaac
     7681 ccggcacctc ctgatcaagc tgattttttg tcatgcccca cacaacatcg ccgtcaaggc
     7741 acgtccgcta cgcgccttcg cccaactgat gcgcatggct ggctttgccc tctttcctcc
     7801 gcgatgatcc tggagattgc catgaaacca ctactgtgct ctgccgccct tgccagctgc
     7861 atgctggccg gctgctcgat ggagccgact tatcaacggc ccgggatgcc cgttcccgac
     7921 agctttccgt cgaccgcgcc aatcacacga accgcgccgt caacggcagc agcacaggcc
     7981 gacgccgagg tagccaacct agactggcat cagtttttca aagatacggc gttgcagcgc
     8041 ctgattgaaa tcgccctcgg caataaccgt gatttgcgcg tcgccgccgc caatatgact
     8101 caggcacgcg ccaactatgg tgttgcacgt gccagccttt tcccggagat tgatctgcaa
     8161 gcctatggcg ggcggcagcg cctgccggcc atgtcacagc agccggccaa cggtctgctt
     8221 ggcccggtcc agaataacaa cgacaaggcg gccaccttca atacctatca ggtacaagcg
     8281 ggcatgacca gctatgaggt ggatttcttt ggccatcaac gagcgatcgc ccacgagtcc
     8341 ggcaagctgg ccgacgccag tgcggccgag tacgaagccg cacgcattgc attgatcggc
     8401 gaagtggcca atgcctatct ttccctcaat gccgatcgcg ccctgttgca gttggcacaa
     8461 cagaccttgg ctgcgcagca acagcacgcc caggttatga acaaggcgta tggcgacggc
     8521 ggcgtgtcgg aattcgacat gcgccgatcg caagcccagg cagacgccgc ccaggtagac
     8581 gtggaaaact tgcaaatccg gatcgccaag gacaccaatg ccatggcggt gctcatcggt
     8641 cagccgttac cagccggcta cagcgcgcca agccaatggg aggatccctt gctgaccgac
     8701 gtgccggcgg ggctgccgtc ctcattgctc gaccgccgtc ccgacatcgt cgctgccgaa
     8761 gaccggttgc gtgcggccaa cgccgatatc ggtcgagccc gcgccgcctt ctttcccaac
     8821 atcgcgctga ccgctgtgct gggcacattg agcggtggcc tttccagctt gttccacgcc
     8881 ggctcggctg cctggaccgg tgcggtttcc ggcacgatcc cgctgctgga ctggggcaag
     8941 aacaaaaacg gactcgctgc cagcaaggct ggttacaccg gcgcggtcgc ggcctatgaa
     9001 ggtaccgtgc aagaggcttt ccgggaggtg gccgacacgc tggccgtccg cgaccatatc
     9061 gtccccgcgc tgaaggccca gcaggctctg gtggaccaat cgcaacgcat ctattccatc
     9121 tcgcaagtac gcttcaagga aggcctcgac gactatatat ccagccagga tgcgcagcga
     9181 tcgctttaca ccgatcagca aaaactggtg agcctcaagc ttgagcaggc cgtcaaccag
     9241 gtcaatctct acaaagctct gggcggcggc tggaatccaa cccacagcgg caacaccaca
     9301 gcacgcgtga cattgcctgt gcggcaatcg tccgtccggg catcgctttg aaaggcaggc
     9361 ttcggcgcga aactttctgc gtaggaattc gagagcgact ggcgccatca cccagacact
     9421 gtggttggcg cgcgctcgct tgcgaatgag gtgcttcggt gatgacccta agaaagtcat
     9481 cgcccaatca acaggcactg agctaccacc gtttcatctt ctgccggccc atacgaagtt
     9541 ggcgaccggt tctgcgggcg gctagcagcg tattcaccgc tagaagtggt cgactgtgcg
     9601 acagtttggc tactcgtcgc tttacacgag ccaatacttg ctcatcagtg ggacaacttg
     9661 accaaacggc catgccgccg ctgggcctcg tcttcccgac gtgtgcgggc atctcccgcc
     9721 caactcacca ggggctggac ttgtatgaca gtcgatgtga cgcggaaact acaaagcgca
     9781 cctcgccgca agcccgaaag ccaatgccag atggacgtca tccctaccct tccccttggg
     9841 tgaagtcacg agtgttgcag tcgcgtcccg ccagggccat cggaaaattt ctaggtaggg
     9901 gtttcgcgcg ctctcccgtc tccggcagcc gtagttgatg taccaaactt cggtgcatga
     9961 agaacaggcc aaggtgatcc tcgaccatcg cgagcctttc tcaagccagg gtaagcaccg
    10021 aaggtagctg gctggccgga tgcatacgca gcagttgata agccactcct gcgacgccgg
    10081 tcatcaagcc cggcacgaaa atatccttgg tcatgccgca ggtgggacca tgactctcca
    10141 gactgctgag tatcgaagcc tgcaggtgtt cgctgctcat gcctttcgga gcctcgcccg
    10201 cggcgatggc gtgctcaaac atttcccaca cgctgagatc gccgtggcac aggcaatggt
    10261 caaggccaag gccaaagtgc caggtcgccg ctgcggcgcg acgtagcagc aaccgcgtgg
    10321 agggatgtgt caattcaggg tcgaggtcta catgcgccaa tccaataccg acggccccat
    10381 tgcaccatgt cgcggcacca agggctcttt cggtcgtgcg cagatccctc caattgccat
    10441 gctccgtatc aaacaatgag tcgtcgtaag caaacgctgc gtccgccagc tcgtcatagc
    10501 gggattcacc gctggcacgg gctaacttgc gcagagccca gccgatgccg gttgccccgt
    10561 gcgagaaacc acccaaaccc gccatgcccg attcgccgcc ccaacaagcc aatccatcct
    10621 ggtagcgagc acgctcgcac aacaagtcac cgaactgtcg agccatcgtc aaatagccgc
    10681 caaccggtaa cgccgcagcc agcgcgagca atggtggaat ggctcctgcg acaccgctga
    10741 gtacgtcgtg ggtggtgtct tccatgacgg cgttgggaag ctgagcagcc agtgcgcagg
    10801 cgcgatgcag catttgctcc tgctcgatgc cccagcgagc cagcgtcagg caagtccaga
    10861 tctgagagcc caggccaaca tagccccccg gcaggcgcgg cctgatcttg atgtcgccgg
    10921 cttcgtcacg tagacgcgta gtttctgctt gatccagggt gcgcaaggat gcactgagca
    10981 gctcatcaag gccatccacc gaattggcgc gcccggcatc ggtttcgcgc agataggccg
    11041 caaccgctac ggcgatgccg gagatgccgt tgtagagatc ctgcttgatc ggttgcgtag
    11101 tacgactagt tgggccgacc accggagcga tccaggcgat gctgccgtcg ccgccgcgaa
    11161 tggcgttggc aaggatctgg cgcatgatcg ccgcagactg atggcgacgg cgccgttcga
    11221 tatcgccttg gcgtgcccgc acggaccata gcgaaccctg cttgggtaat aggccttcgc
    11281 cgataaaagc gctaaccaga gcggcctgga tcacttgtcg atccagttgc aaatccgacg
    11341 tccgccaagc ttgcaacact tcttcaatcc ggtcgccagg cgcaagccac tgcgtcctgc
    11401 caggcccatc aagtcggcca tgacgaggca aggtgctgaa aaaagggatg tcgccgacca
    11461 tcagcgcgtc aatttcagcc tcgatcacgg cagcatcgga gggtgccagc gcagtgcgct
    11521 cggccatttc cgccaataaa tcgaaggcgc gctttcgcgc cgcaccctcg tcatgcagag
    11581 atatggggtg ccacagcatg cggccgatct cggcatagat ttccgtagcc cgcaccacca
    11641 cgcgtaccgg gcaatcagcg aagcgtcgca ggcgcacctg caactggcct tcggcatcga
    11701 gacgccgcaa gcacgcggtc atttcgtcaa aggcttcaag tacccgcggc caaaatcgca
    11761 ccaaagccgg ttgttcgctg ggttgattct gtgcggccat cagctccgtc atgatggaac
    11821 caagacgagc ctcgtcagtg cccacgttct cgataatggc ttgcggctgc atgggttgtt
    11881 gcccccgcaa cctaccaatg ccggaactat cgacaccgcg ccagcccaaa gcttggccgc
    11941 gtgctggcag tagccctatg gccaggacgg tccctccgag cacctcgact gcctgatcaa
    12001 cggcctgccc ccatcctgac ggacgtggcg gcatccttgg ggtaaaaagc gtctcgcaat
    12061 ccaccaccac gggatgtggc cccatcgcga tgagattctc agcatgcaga tcactgccac
    12121 ccagcacgcg cattagcgct aaccaatggc cgatgcctcg gtagaagtcg tgcagctcac
    12181 tgtcgtcggc ggcatagcga tgcgcgacaa actcggccca cccgtaccct ggatagaccg
    12241 caacgcgcgg aactttcatc gatgaggtac taccgcaagt ggccaagtac tcgatcaaat
    12301 cgtgcagctc ggcatctaca gccaccgaat gcggcttata gactaagcgg ccaccttcgg
    12361 tgcgcagcag aaccaccgac tggccgtcgc aatggctgtc accggtaccg atgctcagct
    12421 ccagcagatc ccccggcttg ccgccacaca gtgatgccaa ggcaggccgg tctgttgccc
    12481 accgctgagc aaaacgcagt atggcggaac aacggttatc gacaatacgg gctattcgag
    12541 tggatagcgt ggcatagtgc tcagccaaac cctcccacca gctcaactca gcggcgatcg
    12601 cgcaaaattc ccgccaacgc tgctgggcgt cttcaccccc caaccgtccg gttacccggg
    12661 cggcattgag ttccaacaag agcagccggg tcagcttgcc gtgcagagtc gagagcagag
    12721 acgagcgtgt tgcctggagt atcgttgcgc gctcgcacgc acctagcccc ggtatggttt
    12781 gaagctgggc tgccagtcga accaagccag gctcgacaag gcagcccaaa gtagcggtaa
    12841 aaccgccagc atctgcggat gaaggcatct ggggattacg agccgcagag acagtggcgc
    12901 cgctttcagc gaccttcact agcgaaaccc tctttcaaaa gcgcttgcat agaggcttga
    12961 ttcctcgcaa taagacgatt tcaatgaagg tagacgcttg tcgtcaggag ctgacgctca
    13021 attacagcag ttatcgtgaa tggcggtgcc gcaagtacac aaaaaattcg tagttatcga
    13081 ttcggcggaa ttgacaatat cggccttggc atattttcct ccgatgaaca gtgggccggc
    13141 cggactatcg acgtccgcgc tcgcacgcca ttgcgcaacc aaggcctcac cttccaatac
    13201 cgtgtccata gcactctcct cactgttaag tttcggctga gtaacgaaaa cgacaaagga
    13261 ttccccctac cggccactca ccccatttcg tggccgttcc caaagttagc accaggtcga
    13321 atgcgtggca atgagagcgc taaaagtcaa ggataggcga aaagaggtcg gaagctttag
    13381 catcccttca ttcgatcaag aaatggcaaa ctagtcggag agttctttag gggaatattt
    13441 tcatgccatg gcttccgata tacgcgtcga ggcatgatca ggccgaatta tttgagtatt
    13501 tgaacaactc gccggacctc gctttcatca ggtccgatgg agcgggacgc tggcgggcat
    13561 tcgaaaagct cgaatcgtgg tgtgacggca gatattgcct atggcacact gaaagcggcc
    13621 cactgccact tctccaaact tggggcaaag ctcatcgagt cgtaaacgac ccctttgaag
    13681 gctgggttga agttcgcccc ggcgcagata aatcgcaacc gtatttcggc gcgggccatc
    13741 cgggaatcat ttggttcaat gcctattcgt cagatccacg ttcagcgaat gtctcgacga
    13801 ttggtatttc atccttcgag tggattggaa accactatca agctctcggc aacgtcgccg
    13861 ctccctctac aaaggcccta tggggctcac tgcgtcgatg ggtgagcaaa cgtgccgtca
    13921 aggtcccgcg tgatgggccg gcgcaatcca caccagctga aatttgggcc atgagcgacg
    13981 ctcttgaact attctcgaaa ggcattcctg gagctcccaa tccaccctaa gtgacaacaa
    14041 cacgtgccct tagctcctgc gcgggtgctc ggcgagcgcc tgcgatttcg ccacgatgaa
    14101 agcctcctcg tgccgctcaa tctgcttgct gtcgcaaata cggcatagca gctttcctcc
    14161 ctttccggtc agcatcacct tcgaatcttg cctgcattgc gtgcagatgc tgaagccggt
    14221 cccggccagg tcgagatagg gctcgaacca gcggcattgg gtgttcggca gcatcgccga
    14281 gagccatgca tactcgggca tcggcagccg attgccaacg ccgaggaact tgagccccga
    14341 caggttcgcg agcggtcgca gcgttttgac cttcgatgtg tcgatcgcga gtgactgcag
    14401 ccatgtcatc tggccaaacg tttccagtgc gccaatgtcc tgccgcgtcc acatgctccc
    14461 ggtaacagcg agggattcga gtgaggtcag ccgtgccagc ggcgaaaaat ccgtgacccg
    14521 cttgaaattt tcgatctcga gcaagcgcaa gttcgaaagc gctgcaagtg gctcgacgga
    14581 ctcgattttc gtcgaactgc cgaaatagag ataacgaagg tgccttagat tcccgatcga
    14641 ggagatgtcg cggacattgc tccatttgat ctgcaggcat tcgaggtgtg tcatgcggca
    14701 tgcagcttcg agcaacggcg gcgtgacatg cgaccacagg ctgagccagc gcacattgtg
    14761 caattcaggc aaccgctcga cccattgctt gatcgcctgc ttcttttcct tttcggaaac
    14821 gcggccaaga tcccatgaga gctgcaggcg ctcgcctcca tcatagtcac cgtaggacgc
    14881 gaccgacttt ggccactgcg taacatgaaa tggataggga tcgatgttgg tccagcccat
    14941 gccttgccgc ctttctatca ggtgcctctg aggcaagtat atgcgcgcgc catagcggcc
    15001 tgtccgagtg cgttttgagg tgacaagggc tgtcagcaga cccgatcagg ccgctcgtcc
    15061 catcctgggc ttgacattat ggtgtatata cactacagtt cctcccatga accgcaacac
    15121 gccccaaacc ctagataccg tctccagcat cgtctcagaa gtgacggcgc actgcctgat
    15181 gacgcggacc cgccggatct caagggtcgt gacgagcctc ttcgaccagg agctgcgtcc
    15241 gtacggcctg agctcctcgc agttctccct gctcgtgctg atcgcccgca tggacggcgc
    15301 cagccgggcc gagatcggtc gggccaatca ccaggaacgc tctacgtcca cgcgcaatct
    15361 gcagctcgtg atcgatcaag gctgggctga agaacttgtt ccggaaaaag gccgcagccg
    15421 ccccatcgtg atttcgaagg ctggccgcac cctgctcgct caagcgatcc ccgcgtggcg
    15481 tgccgcccag gtcaaagcca agcaactact tggcgctgac ggggcttctg ccattgtccg
    15541 gctgtcctct ggcctgccca tcgaggagct ggccggctga tccttttttt atcaactatg
    15601 ttgcatatac accatatctc atcgaggaat ccccatgacc atcgttaaag ccgctgccgt
    15661 gcagatcagc ccggtgctct acagccgcga ggccaccgtc gaaaagatcg ttcgcaagat
    15721 ccacgatctc gggcaacggg gcgtccagtt cgccaccttc cccgaaaccg tggtgccgta
    15781 ctacccgtac ttttccgccg tgcaaacgcc catggcacag ctgttcggca gcgaatatct
    15841 ccggctgctc gaacaatccg tgacggtgcc ctcgcccacg acggacgcga tcggtgaagc
    15901 cgcccgcaag gccggcatgg tggtgtccat cggcgtgaat gagcgcgatg gcggcaccat
    15961 ctacaacaca cagttgctct ttgacgcgga cggcactctg atccagcgtc gccgcaagat
    16021 cacgcccacg catttcgaac gcatgatctg gggccagggc gacggttcgg gactgcgcgc
    16081 ggtggacagc aaggtcggcc gcatcggtca gctggcgtgc ttcgagcaca acaatccgct
    16141 ggcgcgctac gcgctgatgg ccgatggcga gcagattcat tccgccatgt atccgggctc
    16201 cgcttttggc gacggcttcg ccatgcgcat ggaaatcaat attcgtcagc acgcgttgga
    16261 atcaggcgcg ttcgtggtga acgcgaccgc ctggctcgat gcggaccagc aggcgcagat
    16321 catgcaggac accggctgcc agatcggccc tatctcgggt ggttgcttca cggccatcgt
    16381 cgcgcccgac ggcacgctgc tgggtgagcc gttgcgcgcc ggcgaaggcg aagtcatcgc
    16441 cgacctcgat tttgatttga tctatcgccg caaacagcag atggattcgc gtggccacta
    16501 tgcccgcccg gaactgctca gcctgctgat cgaccgcacg ccgacggccc accttcacga
    16561 tcgcgccgct cgctccgcca tcgatttggc ccgcgccgaa attctctgac caaggcagat
    16621 ccatcccatg aatacatcga atgagagccc catcctggtc accggcgctg ccggcgacgt
    16681 cggggccgtc ggtcgcagcg tggtcgccat gctgctggag aaaggtcaca aagtacgcgc
    16741 gctggtgcgt cgtgaagacg aacgctccga gagcctgcgc aagcttggcg ccgatgtggt
    16801 agtcggcgac ctgacggatc tgaagtccgt ccatcgcgcc attgaaggct gtcagcgcat
    16861 ctacttcggc atgtcgatct cggcggccta tctggaggcg accgccaatg tggccgctgt
    16921 cgcgcgccac catggcgtcg aagtgatcgt caacatgtcg cagatgacgg tgtcgcagat
    16981 gggcatccat gaaaccactg atagtcctca gcacaagctt cactggctgg ccgaacaggt
    17041 gctggcgtgg tctggcctgc ccgtcgtcaa cgtccgcccg accgtcttcc tggacggctt
    17101 tttcctgcga ctggcggcca tgggcgtgcg cgacaacgac gagctcgtgc taccgctggg
    17161 aggcgccaag acctcgccca tcgccgctta tgacgtagcg cgtgtcgtgg ccacgattct
    17221 cgatgacccg gcaccgcaca tcgggcagat ctacaatctg accggtccgg agtcggtgga
    17281 tgtcgagcag catgcacgtg ccttctccga ggctcttggc cgaacgattc gctatcgcga
    17341 cgtgccggtg gaaccgtggg ccgagaagct ccgtgagttc ggcgttccgc cgcatctgct
    17401 cagccatctc gcggcgatgg cccgcctgca cgcgcaaggt cgctacgacc gcgccactga
    17461 cgacgtcttc aagctgacca gccagaaagc catgagcacg gccgaattcg tgaaacgtca
    17521 tgcggccgaa ttcacgcgtg gccagtgagc cgtacggccg gtctactcct tccaagatca
    17581 ccaacgatcg ctgctaacga atgtaggcac gacctcgcat tcgcaactcg atcactcgaa
    17641 cgaatcaagt atcactttca tgaaatgcct ttcactgttc agctccatcg cgatggcttt
    17701 ggccgtatcg gtatccgcta cgcatgcggc agaagtgctt ccttccggcg ccgcccatgc
    17761 caccggcaag gtgtccgatg cagctctggt caagtcactt ccgggcttca agaacgcgta
    17821 caccgacgtt gacggcgtgc gtctgcacta cgttaccggc ggcaagggcg aaccgctggt
    17881 cctgcttccg ggctggccgg aaacctggtg gacgtttcac aagatcatgc ctgccctggc
    17941 cgagcactac acggttatcg tcatcgacat ccgcggcatg ggtacatcgt cgcggccaac
    18001 agacggttac gacaagaaga ccatggccaa ggatatttac gcactggtcc aatccctggg
    18061 ctacgacaag gtcgccatcg ccgggcatga catcggctcc gccgtggcct atgcctacgc
    18121 ggaaaactac ccgcaggcca ccgacaagct ggtgatgatg gaatttccgc accccgacga
    18181 aagcctgctg acgttcccgc tactgcccac gcaaggtccg gtcggcgaca aagtgggatc
    18241 gtcgcgcccc tacctgtggt ggttcgcctt caatcaggtg aacgaactac cggaaaagct
    18301 gctcgcaggc cgcattcgcg tggagcagga ctggctcttc aaatactttc tgcaagacga
    18361 gaacgccatc gatgcgcggg accgcgcagt gtacgaacag gcctacaaca gcggggaggc
    18421 cattcgtgct ggtaacgcct ggtaccaggc cttcggccag gacgtggccg ataacaaagg
    18481 ctacggcaag cttgagatgc ccgtcctcgt gctggccgga ccggcctacc cgtggatgaa
    18541 ggcagtggtc ggcaagaagg ccaccaagct catcgcgttg ccagtgccga acagcggtca
    18601 tttcgtgcag gaggagcaac cggacttcgt cagcaagacg atgatcgact tcctgcaaaa
    18661 ccctgacaca tcgaaccgat gaaacgacat ttgcgccgcg tcagtcagtt tgtccgatcg
    18721 acgacaacgg gtcgcaacca agaataggag atatcccttg tccaacccta ccgataggca
    18781 accaatgcga aaggcgcctg aacgcctcta tggccataag aacgatttag cagggcgcca
    18841 ggatctgctt gatccccggc cgaacttgcg cgcaaggggg catgccatgt cattcaccct
    18901 cagaagtctc ttcatcgttg cctttggctc cctcttttgc accgctgcct ggggccaaaa
    18961 tacggcagag ggtgaccacc caccggcgct ccttcccttg gcatcggagc cggcaccaaa
    19021 gatcgtcgcc tatgcaccct tggcggagcc gctggctcgt ggcgtcgcca ttattccatt
    19081 tcgaaccgaa aaccttcgaa tcatgcccgt gttcggcacg gcggcggcac aggtatcacc
    19141 acgcctcggt catcttcatg tgactgtcga ccattggccc ggcgggtggg cgcacaccag
    19201 tgtcgatccg gtcattgtga acgcattggc gccgggtccg cacaaggttc tcctcgagat
    19261 agccgatccg acgcataaga tcatgaccag tacaacggtc gatttcgtcg cgccccagag
    19321 gaaagccgac gagcagcatg cgcactagtg tcccgcgcac gagcaaaaac accacttgga
    19381 attgaaccat gaaattcact gaaactgcgc ccacgctgcc gtgcccatcg ggcccgccgc
    19441 cgtggctggg aaaaattgcg caggacgcga cgcttgaagg ggccgttctc aagcgtgccg
    19501 ttcacggcaa ggacaacatt cttgccctca tttcacacgc ccgcagcttg tacgaattcc
    19561 aggactacac gtactacggg ccctggggga gcgagttctt catggagtcg tatcgggcaa
    19621 gcatcaacgg cgtgccgatg gaatgctcgg tgatcgtgca catgaacgat gccggcgaag
    19681 ccgattcgct actgatccac cactacccgc tcgacgccac gctggagttt tcccgcctca
    19741 tgggcgagaa gttcggcgac cagttcgcca acttgtacct caccgccgcc caggccgatg
    19801 gcctggcgaa ggcctcaagc aaaaaataag agggccagga aacagggggc agagcatttt
    19861 ttgcagcatt gaagagagcg ctgtgccatg gcaaggcgtt ttccgcgccc caaagtgctc
    19921 tgatccctag ccaagttctt gggcaacttc ccaaacatgg ccggacgggt cggcgaaggc
    19981 ggccgtgcgg cgcccccacg ggcggtcaac ggggccgttt agcaacctca cgccacggtc
    20041 ctggagcatg gcgcaagtag cgtccacatc ggtgaccttg atcgtgagca gaacatggct
    20101 gcccgccgtc gccggagcca cgggtagcgg ctcaatcagt tccggcgcct cggaacgctg
    20161 gagcaggttg accgcgatgc cgccgaaatc caacaggcag gaaacttcat cccggcccat
    20221 caccttggat tggaagacgc tttcataaaa ggtcatggcc tgcgtgatgt cgtcgacaaa
    20281 caatgtcacg acttcgatag cacttggaac ggacacctgc ttccccttct ccgagctcac
    20341 ttcaaggatt gtcaatggcg ccaggtcact tctggttgac gagcttctca agcgccaacg
    20401 ttcgcgtgat caagtcatcc agctcaaaac tctccgactg taagaatgcc gcgtccccaa
    20461 tgtcctccgg ctgggcagcc agacggtggg tctcgctcaa atgatgcttg agccatgctc
    20521 tttgttcttg ctgcaattga gcccgctgct tgtccttgta cctatgcagt agcgtctgat
    20581 aggccgcatt cagtctcggg tcccatcggc cgacttcagt cttatggcat tccaacattt
    20641 tcccggaagc gccggcagct tgatccaggc atttgctgaa ctgtgcactc tcctgtgcgc
    20701 ttgcagtaaa tgcggcgata cagagggtgg cgctaaaaac gagagatgat ttgcggaaca
    20761 tcgtggcgat cctttgcgtc tctctgaccg aggtagagct taggttggct gatactgaac
    20821 tattttcact gaaattttca agagaatgcg aaggaacaac ggaactcgta tctgggttga
    20881 actcgatata cgccgcaccg tcataatccg ctccagtcac cctgccccgg tccgcttcgg
    20941 gccagcagcg gaggctggtc attgaaccta ccccccagga agcggcgatg agaacaactg
    21001 aagcacctca atccgccgct cgcggggaat cagtagcgtg gcgtaagccc ggagaggttg
    21061 ccgaatcacc gctgcaggcg atgatcgacc aaagcccgcg catgacagcg cagcgccgga
    21121 tgattgcgga catacgtagc ggcaccgcgc cgcgccagct ggcacagctc aacgcggcgc
    21181 ccgacagcga gggcaccggc attccaggcg ccgcatccga acagtcaatg cttgaacaag
    21241 atccggatac ccgcaaggaa caggcacggg aagatctgct ggcaaccatt gacgacctgg
    21301 atggggccga cggccagcaa ttggagcggg tgctggcgca gctccaggaa aaatacgctc
    21361 tgagcaagac cgtggtcgac gtcgacgacc cggaaaacct caaggtggag ctttatgcgt
    21421 ccccgcccct ggtcatcgcc ggcgctgcgc tgggcatcgt cgcgatcgcc acgatgggcg
    21481 cggcctatgc cagctacacc ctccgcagac gggtcaccta tcaccggacc atcaggcgcc
    21541 tgaccactgc cggttaccgc agggacgatg cggaggcgct attccggcag cacaacaacg
    21601 aaagggacct gatcgactgg gcgcccgtcc tgcgtcgaca gattgaagac cgcgtagcga
    21661 tcgatgaagc gatgattgct ggtatgcaaa tctatgaccg gagcgttacg cgcctggtca
    21721 ctgccggtta ccgcaggcac gatgcggagg cgctgtttcg cttgcatggc catgtggatc
    21781 acttgatcgc ctgggcgccg atcttgcgcc gccagattga agacggcgta gccatcgatc
    21841 aagaaatgct cactaacgta ctacggcaac acggcgccgc cgacaaaatg gaagagttac
    21901 agcgggcggg agacggaaaa aatctggctt ggggagaaca caatcccggt ctcaacctaa
    21961 acgaaccagg ccatctaacc gagctaggcc gttggattaa tgacaaaaac aataaccctg
    22021 agcccgatcc ggtgcgcggc accatgaatt gctgggaggt gatctggttc agcgcctaca
    22081 agatgcggta catcacctgg gagcatatgc atgaggtcta tcagaacgaa ctcgaaggga
    22141 cgagtctgaa cacgtatttc aatgagcgca tcagggtggg cgcccagaag aagttcgatc
    22201 cgaacaatgc tgactctggg cgtccattgc gcggagacat cgtgctgttt ggatccgccg
    22261 aagtgcatac ggccatggcc acagggactg aggcgggacc ggaaggaaaa cgctctcccg
    22321 aagtcttcag tctctggacg caacccaatc acaactactt gcagcgcgtg acgataaatg
    22381 cactgctagc cgtcgattca gagtgggacg acgatgacga agaagaagaa aacgaagaag
    22441 aagaagaaaa aaaagaagaa gaagttaaga gtgataaaag cgaattgcgg atcagtatcc
    22501 ggcgcggcaa agacaaagcc gccggacacg gcccgcccgt atggttcttt tctccgaaat
    22561 ggggatgagc cgaatggcgc ttacttaagc gtgcatcttg atgcttggcg tgattcgccc
    22621 ctcttcccta ctgcaccgta ggggagaggg tagattctcg cacggtggct gcatgtcgca
    22681 ggcaatgcag ccatctacga aatgccgcaa cagcacgcgg gcaaagggac cattggggtt
    22741 tgctccgaat ggcgttttct taagcgtgca tctcgatgct tgacgtgatt cccgtagggg
    22801 ggcaggtaga tggcgccagc aagcgagcaa ctcgcttaag tacgtgccat tcgggatgag
    22861 cccatttc
//
