LOCUS       NZ_CP034587            23479 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6892501
            Orig. end                         :: 6915980
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23479
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="38"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23479
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23479
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13479](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13479)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            146..>438
                     /locus_tag="EKH77_RS30670"
                     /old_locus_tag="EKH77_30670"
                     /pseudo=""
     CDS             146..>438
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044646.1"
                     /locus_tag="EKH77_RS30670"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="EKH77_30670"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTDAARERSGPLLPKRGGRGRPWRDHRQVVDGVLWRLRTGAP"
     gene            complement(557..1365)
                     /locus_tag="EKH77_RS30675"
                     /old_locus_tag="EKH77_30675"
     CDS             complement(join(557..1026,1026..1365))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="EKH77_RS30675"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EKH77_30675"
                     /product="IS5 family transposase"
                     /protein_id="WP_126917459.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MRDDLVADDLWERVAPLLPPAPERRRRYPGRLRVPDRAALAGIMY
                     VLRTGVAWRDVPAETVGCSGVTAWRRLRDWTEAGVWPHLHAALLTELRRADSLDLDDCS
                     VDGSHVRALKRGDHVGPSPVDRARPGSKHHLIVDRHGTPLAVTLTGGNRHDVTQLLPLL
                     DAVPPIRGRRGRPRRKPRRLYTDRGYDFDKYRRLLWKRGIKPLIARRGVAHGSGLGKVR
                     WVVERAFAWLHQFKRLRIRYERRADLHQGLLELACSLICLRRLRTSF"
     misc_feature    1413..1427
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    complement(1648..1662)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    1694..1703
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            2090..4000
                     /locus_tag="EKH77_RS30680"
                     /old_locus_tag="EKH77_30680"
     CDS             2090..4000
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024816.4"
                     /locus_tag="EKH77_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30680"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_164737914.1"
                     /transl_table=11
                     /translation="MLYRPEHATLLPPGAFRPAAEVQSAPGLANFPKKSGVFVGRNHAL
                     ADLDGAMTRPGGAVIQAVHGLGGIGKSALAVHWAVSRAADYNPIWWIAADSPAAIDAGL
                     AALAVALQPAMSGVLEVQELRGWAVRWLAAHDQWLVILDNVSNPGDVEPLLANAPTGRY
                     LITSRRATGWHGIAEQIRLDVLDHAEAVDLIARILTHRGPHDLDGAGDLCTELGCLPLA
                     IEQAAAYCAEAGATPRRYLALLADYPVTMYNVTAEGGDAERTIARIWHVTLDRLASVPF
                     AEHFLRILAWYAPDGIPLSLLNGLAEPPAILHAIGRLAAYSMLTVDGETLAVHRLVQAV
                     TRTPDHDDPHRQSQDIEKAWTQATKQLLRGQPHGMGPERWPAWRSFLPHVDALTSYSRP
                     AVDTFEIAELLSDAGAFHYFQFSYGRAIECLERAISSYRRSVGSLHQRTLVARNNLASV
                     YLATGHEGRAITILEKILAAHERIAGENHPECLTTRNNLAAAYRAADRLNEAIPLYEKT
                     YFALSETLGLHRFTMMAAHNLAAAYSDTGHRDDQAIPLYGILLAVQWQDLGGSDPDTLR
                     TCHSLALLYDAADDMDRAIPLYEIAFAGRRRLFGDDYPDTLDSRNHLIRAYYRRIMRKA
                     T"
     gene            <4102..4332
                     /locus_tag="EKH77_RS30685"
                     /old_locus_tag="EKH77_30685"
                     /pseudo=""
     CDS             <4102..4332
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="EKH77_RS30685"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30685"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="YRRLLWKRGIKPLIARRGVAHGSGLGKVRWVVERAFAWLHQFKRL
                     RIRYERRADLHQGLLELACSLICLRRLRTSF"
     gene            4671..5354
                     /locus_tag="EKH77_RS30690"
                     /old_locus_tag="EKH77_30690"
     CDS             4671..5354
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30690"
                     /product="hypothetical protein"
                     /protein_id="WP_126917461.1"
                     /transl_table=11
                     /translation="MFELLPGVGVALPGDTGTLRFGSDWRTAAGVLAGLGRVRPLPEAS
                     CTHTARWGDVEVTAHAGQAGRAAATSGELPLRSVVLSRGGSASGVPGGTPVVLGDIDLF
                     GYPAAEVLEALGDHRPPELQIRPADWRGYLTSVTLHTIPPPAPAGRRARAGAEAAEVER
                     ALAELEPLWTTERDQWQLLEAGGGHLPCHRGDPQTMLMICDEAVARRVTAAMLAAGVEV
                     VPEQL"
     gene            complement(5639..5770)
                     /locus_tag="EKH77_RS34480"
     CDS             complement(5639..5770)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS34480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_276319248.1"
                     /transl_table=11
                     /translation="MPKMTHQEWDAAALRLLGAPYVFAATSPRQQHEDWTHGVLAVP"
     gene            complement(5906..>6313)
                     /locus_tag="EKH77_RS30695"
                     /old_locus_tag="EKH77_30695"
                     /pseudo=""
     CDS             complement(5906..>6313)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741226.1"
                     /locus_tag="EKH77_RS30695"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30695"
                     /product="DUF4232 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RADDLEITAKDGTIDGDPDGTVVVELKNRGGRSCAISGYAGVDLK
                     TNAGSLSAKRTGEQAPSAIVKAGESTFFGINYPYNKSGGSGIRVTGVLVTPPNETKTVS
                     LPWPGAATLPVTDGSGSPVKVGPIGSAGQGG"
     gene            complement(6494..6991)
                     /locus_tag="EKH77_RS30700"
                     /old_locus_tag="EKH77_30700"
     CDS             complement(6494..6991)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30700"
                     /product="Tautomerase enzyme"
                     /protein_id="WP_126917463.1"
                     /transl_table=11
                     /translation="MPMLDVYIPDGALQPDAEAALLNRITEILIRNEGFDPADPVVRSV
                     SWLWLHRPAGVYIGGEPADAPRYKVVPSVPEGQLDERKRASVIAEVTEAILDAENDAWP
                     RDARRIWVFPTEIPEGHWGGRGRIRPLATILARLSGGDTKRARTLARERIAASRAEHAR
                     LP"
     misc_feature    complement(6991..7005)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     gene            7089..7580
                     /locus_tag="EKH77_RS30705"
                     /old_locus_tag="EKH77_30705"
     CDS             7089..7580
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998300.1"
                     /locus_tag="EKH77_RS30705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30705"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_126917464.1"
                     /transl_table=11
                     /translation="METRRIDPVNCSVARALSVVGERWSLLIVREALDGARRFGEFHSR
                     LGVARNLLATRLDTLVAAGVMRRVPYQEPGDRQRFAYELTERGWALRPTLVALLEWGDA
                     YLADPQGPSVIVRHRPVDDASPCDEPVKVVLECTAGHSHLAPEDVCRTPGPGARFVEGS
                     "
     misc_feature    complement(7818..7831)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            7850..8713
                     /locus_tag="EKH77_RS30710"
                     /old_locus_tag="EKH77_30710"
     CDS             7850..8713
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039441.3"
                     /locus_tag="EKH77_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30710"
                     /product="DUF6424 family protein"
                     /protein_id="WP_346429089.1"
                     /transl_table=11
                     /translation="MTDPAARRRLNQGGDAPIGAPCAHGANSNGSREGRVTMTPQTDPS
                     KPHVEHEDKPWTINIPGHPPRSDSPEYVASRKQMHKLVDSLDHPFYGPEPVEDHHGGGL
                     WVKDDQGWFMVRNMAGIEWSAQFCADPAKVDLLRQNARRLYAGFPDAVEELGIRELLDT
                     PITDADGVQRWTDSICNASVPLAKKDHSAELPKGGGVHHYPSPITEIGFFKRDDFILWV
                     TDDAGEPVAVAPVDRRGSGDGRVNVLFASEQSPLHAELHKAQAKGQALVLDAGHAVARA
                     AFARQA"
     gene            8856..9661
                     /locus_tag="EKH77_RS30715"
                     /old_locus_tag="EKH77_30715"
                     /pseudo=""
     CDS             8856..9661
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612359.1"
                     /locus_tag="EKH77_RS30715"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30715"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVTSLITPASEGPCWFRILPCLMSRMSSLSMSRG"
     gene            complement(9669..9866)
                     /locus_tag="EKH77_RS30720"
                     /old_locus_tag="EKH77_30720"
     CDS             complement(9669..9866)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30720"
                     /product="hypothetical protein"
                     /protein_id="WP_126917467.1"
                     /transl_table=11
                     /translation="METSSPGRISGDIALEGVGGEAMTHVGAEMLPAAETAPVLPALIL
                     VAYLVDRVPGRSRLRLTMGH"
     gene            complement(10001..11212)
                     /locus_tag="EKH77_RS30725"
                     /old_locus_tag="EKH77_30725"
     CDS             complement(10001..11212)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="EKH77_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30725"
                     /product="terpene synthase family protein"
                     /protein_id="WP_126917468.1"
                     /sec_met_domain="T1TS (E-value: 7.3e-46, bitscore: 156.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDHQGPTAPGQSDTGEELVIPRLTYPWPTIDSPLADALDEET
                     FRWYDEDYADVFPDPADRERYRKQLLSRVTPYMFPTANDIDRLRPAARWMNHITLMDDF
                     FDLTPAEEIAPLRNRIYQVMTGRDDPRPGELGLLRQLAAAREEFRRYVPQFWIDRMALS
                     HWQYIHYGLMEEVAFRRQGIYPSIHRCRMIRMHSIGQRPFADQIEPVTGVLLPGDVFNH
                     PVVQRLRDLQACVIALQNDISSLHKELALGQNEVVSQILSVRHHRQVSLQQAVDEVVAM
                     HNRDVEEIWSLQQCLPDFGPHQAAVENYVQHLGIQIAGLQNWYDRIGRQFRYGYGGFVI
                     PQYGRKEIKIKTKMAYVDPDGTPYEPPRIYGYGREERSAGAIDDALRYANDNGTPWQGQ
                     EKAD"
     gene            complement(11209..12204)
                     /locus_tag="EKH77_RS30730"
                     /old_locus_tag="EKH77_30730"
     CDS             complement(11209..12204)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954462.1"
                     /locus_tag="EKH77_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30730"
                     /product="terpene synthase"
                     /protein_id="WP_240667629.1"
                     /sec_met_domain="T1TS (E-value: 6.7e-45, bitscore: 152.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDSTTMARLRYPFPSLMNPHAEALQQHTDRVWIDEEWAGIVPPE
                     IAEGFKQVRTAYMTAFFFPSATWERLIPLARMMLFSLYQDDVYEHASPDQVQHLRHQTV
                     AVARGEITPQEAGVPLARAIAQIRAEALAFIPPTSVARWADDLDLYFQGLEAETTHLAA
                     DTVPGIEEYMAMREKALMIHPFLALKEIETGTVLPEGIHDHPVVRRLKSLTVRITGWFN
                     EFQSYDKDMRTGMGNVNFINVLAHHHRICIDQAREELFSIHDRELDEFVRLQRDLPDFG
                     RWSDPVAQHIHHFSFVISGWRGVDKHIHRYDPEYYPDQDTLCATAGKDPT"
     gene            complement(12391..13479)
                     /locus_tag="EKH77_RS30735"
                     /old_locus_tag="EKH77_30735"
     CDS             complement(12391..13479)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957287.1"
                     /locus_tag="EKH77_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30735"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_126917469.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.2e-46, bitscore:
                     155.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPTPPLTPAVDLAGTREAVDTCLTGFLDRKMRAAASEGMPTEA
                     ISVLRRFLTSGGKRLRPLLCVCGWCAAGGHGDTTTIVRAAASLEMFHAFALIHDDVMDR
                     AATRRGAPTVHRRLAQHHREGRSMTAARHLGVSTAVLVGDLALAWSDELLPTVDLTSRQ
                     LGAVLPLIDVMRSEVMYGQYLDVTAAGHPTGDVEYALRIARYKTAKYTVERPLHIGAAM
                     AGAPLAVREALSAFALPVGEAFQLRDDLLGVFGKPQITGKPSLDDLREGKHTVLVALAL
                     ERATPSQRHILDALLGNPDLDDAGADRIRRVLTATGARAEAEHMIIIRRTQALRVLEAA
                     RLPPAATAALRKLTGAATARTS"
     misc_feature    complement(13813..13831)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.67"
                     /tool="antismash"
     misc_feature    complement(13913..13926)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.53"
                     /tool="antismash"
     gene            complement(14258..15373)
                     /locus_tag="EKH77_RS30745"
                     /old_locus_tag="EKH77_30745"
     CDS             complement(14258..15373)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575794.1"
                     /locus_tag="EKH77_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30745"
                     /product="serine/threonine protein kinase"
                     /protein_id="WP_164737916.1"
                     /transl_table=11
                     /translation="MKVGSWNEWDPLKHVVVGRADGTMVQAPESAVVRDWPEDGFPLGT
                     YGPLPEEMTAAANEQLDNLAHVLESRGIRVDRPRPLDFSRPVATPEWSQQSMFGAMPVR
                     DVLVVIGNELLEATMSFRSRWFEYLAHRPLIESYYRADPGMRWEAAPKPRLTEASYRPG
                     FRDEYDALPYEEQIARVRAGELVLTEAEPLFDAADIARCGKDLFVQQSLATNAAGIRWL
                     RQHLPEHRVHGVTFENLHPMHIDATWVPLRPGLVLHCAERPADEDLLQYFKINDWQVVR
                     AATPGRQTPPPLSACSRWLSMNVLVLDPGTVCVEASETAQMEQLDRLGFEVVPVPFWDV
                     APFGGGLHCATLDVHREGVLEDYFPRRSGRF"
     misc_feature    15600..15609
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            15628..16137
                     /locus_tag="EKH77_RS30750"
                     /old_locus_tag="EKH77_30750"
     CDS             15628..16137
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30750"
                     /product="hypothetical protein"
                     /protein_id="WP_126917471.1"
                     /transl_table=11
                     /translation="MPALLTYFELTRAHGLSPFRAARRTKAPGGGAHLMRTGLLCIAAG
                     LLTGSLGGGRPTPLWLNAGSCALTGCGLGLANGAAMTTVAMGTSGATGATGTPPHLALC
                     SAAPALALTAVALTRRGGGLAPLLPSGVRALTLSASGRAKRSPRGWDDRWGWPGIPPDR
                     ATALRF"
     misc_feature    16246..16255
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.35"
                     /tool="antismash"
     misc_feature    16253..16267
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
     gene            16386..16997
                     /locus_tag="EKH77_RS30755"
                     /old_locus_tag="EKH77_30755"
     CDS             16386..16997
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561593.1"
                     /locus_tag="EKH77_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30755"
                     /product="response regulator transcription factor"
                     /protein_id="WP_240667630.1"
                     /transl_table=11
                     /translation="MRVVLAEDHPTVRAGTRAFLEPEGFVVVGEAACEREALEVVSEQR
                     PDVLMLDMRLESGLALKVIPQFLAAAPGMGILVQSCYEDRAIICGALAAGAAGYLLKSS
                     PVSELVLAVRTVASGGRYVQPSLGAGLARDQGREPELQLRERQVLGLLAEGHTNREVAA
                     RLTVSVRTVESVRAALRARLGLVTRAELVAYARQNRSADV"
     gene            16990..18027
                     /locus_tag="EKH77_RS30760"
                     /old_locus_tag="EKH77_30760"
     CDS             16990..18027
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="EKH77_RS30760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30760"
                     /product="sensor histidine kinase"
                     /protein_id="WP_126917473.1"
                     /transl_table=11
                     /translation="MCSGTAGPATARQPLALGALSGFCIAVTLVSVVAYAANFLTHDRL
                     PPRTISTPSIALATGTLALLTCGMRRARRLLIMICCGFTALSVDRLAHSAATDHVALAF
                     LLAASAYAVPAWPEVKVLLSRGRASAMVERQEHHAGLLAGELHDEVLQLLALTRRRLDA
                     ARALDDPDALRAAMEDASRTLDEQAGTLRRIIATVSPAAVQGLGLAESVTSLAAQVAAE
                     NGLVVDVEVQGDRPHVCAGENGVNLAVYRVAQEALTNVVKHADARHITLALACRDEGIS
                     LTVTDDGRGLGPNPPRVTEGYGMQGMRWRCEAYGGTFSARTAGAAGTVVRAVFPLRSCR
                     RARSS"
     gene            complement(18089..18964)
                     /locus_tag="EKH77_RS30765"
                     /old_locus_tag="EKH77_30765"
     CDS             complement(18089..18964)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30765"
                     /product="hypothetical protein"
                     /protein_id="WP_126917474.1"
                     /transl_table=11
                     /translation="MHHSTRRAATLCAATAVAALCGVVPAQAADGPTTPAATDITAAQK
                     VLRSGQLRDTVARFLTAAAERDDPNGDAQAGGGGADGGVAGAPRSPERSPATAPGFDLK
                     KPVPFYELSPEFVAGKAKATAGAALRLSYLASRVSAANGRQAAVLLAPGQGGSAWQLAG
                     IRDGDTDISAAERGTDQERTFMEPQIHGWYRLTGSGSVEPLNKEARTALQGKARVPLAE
                     YQQLVAKRYGDKLPGSAYDRKGLAGGYALAEDQAATAPSRPWLPAASGAAALTVSGAAV
                     LHLYRRRRSA"
     gene            complement(18989..19846)
                     /locus_tag="EKH77_RS30770"
                     /old_locus_tag="EKH77_30770"
     CDS             complement(18989..19846)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023802.4"
                     /locus_tag="EKH77_RS30770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30770"
                     /product="papain-like cysteine protease family protein"
                     /protein_id="WP_164737917.1"
                     /transl_table=11
                     /translation="MLLATTGAAVLSGGLLLSLSPQAQASVTGSVTGGRGNFSTVNQRS
                     QPSLSAAITGKSWVGDQIPMTCRTTGDVVENNSRWIWSGKYYIADAFIRENTGGLPLCA
                     STRPTDRPTGNPTDRPTGNPTGRKALDISMQKQVKDQWCWDATGLTIANFWGYNRYDQY
                     DFCRLAAQNNRLDCNNRPATLGDMANALRNMGFRNSGSDLYRNASFGETRTEIANGRPF
                     AVRIGWNSGGGHMNVVYGYDSTTSMIAVGDPWPTTKTYTWWNYSTYSGNNSFRWTHTRV
                     GIHG"
     gene            complement(20260..21810)
                     /locus_tag="EKH77_RS30775"
                     /old_locus_tag="EKH77_30775"
     CDS             complement(20260..21810)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30775"
                     /product="hypothetical protein"
                     /protein_id="WP_126917476.1"
                     /transl_table=11
                     /translation="MRNLRRGAALAPVLLTSLSLALAGCSPLGSGSTDASDETANSAIS
                     APPNDFLLGKTPPAGSEPSAVAIPAGGGVKTRKSAVKVDSIDRNSGRAVISQTLARPTP
                     SASGTPGPSATGAEKQPTEGKPVAVGDIVASKPVPGAPQGLLAKVTKVERTTSKGTEVR
                     TAPVDLSTVLGDTEVKSKLPVAPSGFKVDSLVPGVKVSWAERGNVHAGPEGLKLPFGSL
                     RVDVDTSLDTEKDAKGEGVESPTKASFKGFVQLAPEVDFNYYGRGSGDGPSGTGLRLTG
                     DWSSAFHFKGRTAPTTNGKPVRVPFVVLHANPTFYIGELPVTVNIDLTCYVLIDAAGRM
                     SLDVQQDPVKGDFTLGSAFSLREGWQPEAKAGFTPGTLKASASAAADAKIRFGTEANLG
                     LYGSVGVKGDVAAPYVRTEVKGGAGASTEGRAAADADWKLFAGVDLEGWVMPYLKIGGV
                     QALAVRLPMPQVRREVQLAHGKGAIRIPQPRTPQDDTKPGDTKPGDKDQSGGGRPRRH"
     gene            complement(21938..22837)
                     /locus_tag="EKH77_RS30780"
                     /old_locus_tag="EKH77_30780"
     CDS             complement(21938..22837)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012427.4"
                     /locus_tag="EKH77_RS30780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30780"
                     /product="glycosyltransferase"
                     /protein_id="WP_126917477.1"
                     /sec_met_domain="MGT (E-value: 5.2e-36, bitscore: 123.3,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPGVRAAVGEFRPDVLVADQQAVAGGLVAERLGLVWATSATTTA
                     GFTSLSGLPEVDAWIAGRIGELRRRIGDPRSTADPRLSDRLVLAFSTEALAGPVPPGGG
                     QVRFVGPSLTARPATGDFPWHRLDPRTPTVLITLGTANAEVAPRFLAACAQAVRGRPDR
                     AQAVIVDPTGTVPEFADRVLVRPHVPQLAVLERCDAVICHGGHNTVCEALWHGLPLVVA
                     PIRDDQPAVAAQVTDAGAGVRVRFNRATADVLGTALDTVLHEPGCREAAGRVRASFRAA
                     GGAAAAAAHLEALAAGAK"
     misc_feature    complement(23290..23304)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.57"
                     /tool="antismash"
ORIGIN
        1 agtggccaca ccgcggcggc actggtccgc cccgacggca ccgtccaacg caccgcaccc
       61 gacccgaagg ccctgtgcgg gctcctgcgc gcaccgagct cctacgggcg ttttcgaggg
      121 tgatcctgtt tcagtgcgag gcgagttgac ggacgcggca cgggagcgga gtggacctct
      181 gctgccgaag cggggcggac gtggccgtcc atggcgtgac caccgccagg tggtcgacgg
      241 tgtgctgtgg cggctgcgga ccggggctcc ctgacgcggt ctccctgacg cggtctccct
      301 gagcggtacg ggccatggca gaccgtctac gagcggttcg cccgctggga agtggacggg
      361 atctgggcga cgttgctgga gcacctccag gtttgcgacg acacggtggg ccgggtggac
      421 tggacggtgt cagtcgactg tgacgggccg acctcgcacg acaccggcac gggtactggg
      481 cgacaaagcg tatgccagct gggcgacacg ccgcttgctg cggcgccggg ggcatcgctg
      541 ccacttactg atcgtttcag aatgaggttc gtaggcggcg gaggcatatg aggctgcagg
      601 ccagttcgag caggccctgg tggagatcgg cgcgtcgctc gtagcggatg cggagccgtt
      661 tgaactggtg cagccaggcg aaagcgcgct cgaccaccca gcgcaccttg cccaggccgg
      721 atccgtgggc gacgccgcgt cgggcgatca gcggtttgat gccgcgtttc cacagcaggc
      781 ggcggtactt gtcgaagtcg tagccccggt cggtgtacag gcgtcggggc ttgcggcggg
      841 ggcgtccccg tcggccccgg atcggcggga cggcgtcaag cagcggcagg agctgggtga
      901 cgtcatggcg gttgccgccg gtgagcgtga cggcgagcgg ggttccgtgc cggtcgacga
      961 tcaggtgatg cttggagccg gggcgggcgc ggtcgacggg cgaggggccg acgtgatccc
     1021 ccctttgagg gcccggacgt gcgatccatc cacggagcag tcatccaggt ccaacgagtc
     1081 cgcgcggcgg agttcggtca gcagtgcggc gtgcaggtgt ggccagacgc cggcctcggt
     1141 ccagtcccgc agccggcgcc aggccgtgac tccggagcag cccacggtct cggccgggac
     1201 gtcgcgccag gcgacgccgg tccgcaggac gtacatgatg cccgcgagag ccgcccggtc
     1261 cggaacgcga agccgcccgg gataccggcg gcgccgttcg ggagcgggtg gcagcagcgg
     1321 ggccacccgc tcccacaggt cgtcagcaac aagatcatca cgcacccgga caccctgccg
     1381 accaagatcg gcaaacacaa ggctcgcagc tcaactcatt ctgaaacgct cagttagggc
     1441 gaccacgttg ggcttggcgg cgaacgctgt gggcatgcgt tgtggattca gaacgcagcc
     1501 cgcctcgctg cgtgctgtcc tcgggatgcg agcatccccc aaccgaggtg gcattgatag
     1561 taaaggtggc tacgtcaccg ggagctgact caccagttcc ctccgccggg tcggcggtgc
     1621 agatcactcg gcgatacacg cggaggatga acatgaatgc caggtggtgg gtgtctggaa
     1681 tcgtaacgct ggccgttttt tgcgtattca catggctcgc gggcgcgttt gcgctaccag
     1741 ctctgatgga atcctcaccg gagcggtggg gggtggcatg tggcgtcggg ctggccctcg
     1801 ccgccctcgc ggccctatgg ggagcgtcgt gggcgaaacg gatgagcccc acagtccaac
     1861 atccctcagc tgaggatagg tcgatcaacg ccggcgggga tatctcggga atcgcttcca
     1921 ccggcgatga cacaaccaat acccagagcc catgagtagc cgacctcggt ggggaaaaga
     1981 tgaacccccc acgccagcat tgccctcctc gaacacggcg gtcgatcggt cgatcagcgc
     2041 ggaaggtgat atctcgggaa tcgcttccac cggcgactat gcaacgaacg tgctctaccg
     2101 tccagaacat gccacgctgc tgcccccagg agcattccgg cctgcggcgg aggtccaatc
     2161 cgcacctggg ctggcgaact ttccgaagaa atcaggggta ttcgtaggtc ggaaccatgc
     2221 gctggcggat ctggacggag ctatgacccg accaggcggg gcggtaatcc aggcggtaca
     2281 tggtcttggc gggatcggca agagtgccct tgccgttcat tgggcggtca gccgtgccgc
     2341 cgactacaac ccaatttggt ggattgccgc cgactccccg gccgccatcg acgccgggct
     2401 ggccgcgctt gccgtcgccc tacaaccggc gatgtccgga gtcctagagg tgcaggagct
     2461 gcgcggatgg gcggtacggt ggcttgcagc ccacgaccaa tggctcgtga tattggacaa
     2521 cgttagcaac cccggcgacg tcgaaccttt gctagccaac gcgcctaccg gccgctactt
     2581 gatcaccagt agacgggcta ccgggtggca cggaatcgcg gaacaaattc gcctagacgt
     2641 cttggaccat gcagaggcag tagacctcat cgccagaatt ctgacccacc gcgggccgca
     2701 cgacctcgat ggcgcagggg acctatgtac cgagttggga tgcctgccac tagcgataga
     2761 acaggccgct gcatactgtg cggaggcagg cgccaccccc cgccgatacc tggctctgct
     2821 ggccgactac ccagtcacca tgtataacgt gactgccgaa ggcggggatg ctgagcgcac
     2881 aatcgcccgg atctggcatg taactctgga tcggctggct tctgttcctt tcgctgaaca
     2941 cttcctgcgg attctggcct ggtatgcgcc agatggcatc cctctctctc tgctaaatgg
     3001 acttgcggaa ccgccggcaa tacttcatgc gatcggacga cttgccgcct atagcatgct
     3061 caccgtggac ggtgagaccc tcgcggtgca ccgactagtg caggccgtta cacgcactcc
     3121 tgaccacgat gatccacatc gccaatcgca ggacatcgaa aaggcgtgga cgcaggcaac
     3181 caaacaacta ctccgggggc agcctcacgg gatggggccg gaacgctggc cggcatggag
     3241 atcgttccta ccccatgtgg atgccctcac atcatattcg cgacccgccg tcgatacctt
     3301 cgaaatcgcc gagcttctct ccgacgcggg agcattccac tactttcagt tttcttatgg
     3361 tagggcgatc gagtgcctgg agcgtgctat atcttcatat cggcgttctg tgggaagcct
     3421 gcatcagcgc acactcgtcg cccgcaataa cctggccagc gtctacctgg ctacaggcca
     3481 tgagggtaga gccatcacca ttctggaaaa gattcttgcc gctcacgaac gcatcgccgg
     3541 tgaaaatcat cctgagtgcc tgacaacgcg taataatctc gccgctgcct atcgcgcggc
     3601 agataggctg aacgaggcga tccccctata cgagaagacc tattttgcgt tgagtgaaac
     3661 cttgggtctc catcggttca cgatgatggc ggcgcataat ctcgccgccg cctacagtga
     3721 tactgggcat cgagatgacc aggccattcc cctgtacggg atacttctcg cagtccagtg
     3781 gcaggatctg ggagggagtg accccgatac gcttcggaca tgccatagcc tcgcgctgct
     3841 ttatgatgcc gcggatgata tggaccgggc catcccgctg tatgaaatag catttgctgg
     3901 tcgacgtcga ctgtttggtg atgactatcc cgacaccttg gattcacgca accatctcat
     3961 aagggcctac tatcggagaa ttatgaggaa ggctacctga accccgcatc tcgggaaatt
     4021 cgccttgccg agtgcgaagc ggcaatgagg catggacggc gactgccagg tccgctgcta
     4081 tgacggctgg cactggccaa gtaccgccgc ctgctgtgga aacgcggcat caaaccgctg
     4141 atcgcccgac gcggcgtcgc ccacggatcc ggcctgggca aggtgcgctg ggtggtcgag
     4201 cgcgctttcg cctggctgca ccagttcaaa cggctccgca tccgctacga gcgacgcgcc
     4261 gatctccacc agggcctgct cgaactggcc tgcagcctca tatgcctccg ccgcctacga
     4321 acctcattct gaaacgatca gttagggccg gaagcctcgg gccaaggaag gtcccgaggc
     4381 ttcccccgcc cgaggccctg ggaagcggac tgttctcaga gcaggctagc cagctgggtg
     4441 atcacgcctc cgacgagggc gtggagcccg accacggcta ggcccaagag ctgaccgaca
     4501 atgggcaaga gcatcgctgc actcctgtcg tatgagccgc tcatcattgc ggcctggtgg
     4561 ccggatcaac gacgccccgt ccggccagac acgctctaca gcaacggctg cccgacgggt
     4621 tagaggcagc cggcttgcct cctcgccggg ccccggtgca ccatcggccg atgttcgagt
     4681 tgctgcccgg tgtcggggtc gccctgcccg gcgacacggg taccctgcgc ttcgggtcgg
     4741 actggcggac ggcggccggg gtcctggcgg ggctcggccg cgtccggccg ctgccggaag
     4801 cctcctgtac ccacaccgcc cgctggggcg acgtcgaagt gaccgcccac gcgggccagg
     4861 cgggccgggc cgcggccacg tccggcgaac tgccgctgcg ttccgtcgtg ctgagtcgcg
     4921 gcgggtcggc gtcgggcgtc ccgggcggca cacccgtcgt cctcggagac atcgacctgt
     4981 tcggctaccc ggccgccgag gtgctggagg ccctcggcga ccaccggcct ccagagttgc
     5041 agatccggcc cgctgactgg cgtggctacc tgacgagcgt caccctgcac accatcccgc
     5101 cgcccgcgcc ggccggccgc cgtgcgaggg ctggggccga ggcggccgag gtcgagcgcg
     5161 ccctggccga actcgagccg ctgtggacca cggaacgcga ccagtggcag ttgctggagg
     5221 ccggcggcgg ccacctgccc tgccaccggg gggatccgca gaccatgctg atgatctgcg
     5281 acgaggctgt ggcccgacgg gtcacagccg cgatgctcgc ggccggcgtg gaggtcgtcc
     5341 cggagcagct ctgaggcggt ccggcgccct cgggtctgga tgccgcgggc ggttcgggat
     5401 gcggccgacc ggggtgcagg cggtgtggcg ggaccgggag gtgcgggatg gacccgtccc
     5461 gcacgggttc agtccgcagg tcgtgccgcg gcccggtgac tggttccccc gtgtcggtgc
     5521 ccctggcgtg acggagccga gaggcacatg atcgcaggcc gtgccaagag cccctatgcc
     5581 ttccggacag cagttgccgc accgcgatcc gcagacggcc tgccccggcg gcccgcgttc
     5641 acggcacggc gaggacgccg tgcgtccagt cctcgtgctg ctggcggggg ctggtggccg
     5701 cgaagacgta gggggcgccg agcagccgta gtgccgccgc gtcccactcc tggtgcgtca
     5761 tcttcggcat gaccgcggtc cggcgtcggt gacgcgcact gcctgcggag aacccgacgg
     5821 cctctacccc ccccgtcggg gctcttcgag gccgggcccc tggggcatcc ggcggtgtgg
     5881 tgtcacggtt cgccggtgcg ccggatcaac cgccctgacc ggcgcttccg atcgggccga
     5941 ccttcaccgg ggagccggag ccgtccgtga cgggcaacgt ggcggcgccc ggccaaggaa
     6001 gggagaccgt cttcgtctcg ttcggcgggg tcaccagaac tcccgtgacg cggataccgg
     6061 agccacccga cttgttgtac ggatagttga tgccgaagaa cgtcgactcc ccggccttga
     6121 cgatggccga gggggcttgc tcaccagtgc gcttcgctga cagtgacccc gcgttggtct
     6181 tcagatcgac gcccgcgtac ccggaaatcg cacagctgcg gccaccccgg ttcttcagct
     6241 ccaccacgac ggtgccatcg gggtcaccgt cgatggtgcc gtccttcgcc gtgatctcca
     6301 gatcgtcggc gcggccgtcg cccgcgccct cgccgccatg ctccgccatc ccggcccgtc
     6361 cggcggcaag gacaggactg gcatctccct cgacgaggtc ttcgcccacc tgcgcatctc
     6421 gtccgacggg aactgacgtc gccctgtcgg ctgtgtcacc ggctgtatcg atctccgctt
     6481 cgtgccccgc tcgtcagggc aggcgggcgt gttcggctcg gctggcggcg atccgctcac
     6541 gcgcgagcgt acgggcccgc ttggtgtcgc cgccgctgag ccgggcgagg atcgtcgcga
     6601 gcggtctgat ccggccccga ccgccccagt ggccctcggg gatctcggtg gggaacaccc
     6661 agatccggcg ggcgtcacgc ggccaggcgt cgttctcggc gtccaggatc gcctcggtga
     6721 cctcggcgat gacgctcgca cgcttgcgct cgtcgagctg gccctcgggg acggagggga
     6781 cgaccttgta acgcggcgcg tccgcgggtt ctccgccgat gtagacgccg gccggccggt
     6841 gcagccagag ccaggagacg gaacggacca ccgggtcggc ggggtcgaat ccctcgttgc
     6901 ggatgaggat ctcggtgatg cggttcagca gcgccgcttc ggcgtccggc tggagcgcgc
     6961 cgtcgggaat gtatacgtcg agcatgggca tggccgatcg attcccctct gggtttagtt
     7021 ctgcaactca gatgggagcc tatgagggct gagtacagct tgtaaaccca gatggataca
     7081 ctcgtcccat ggagacgcgg cgaatcgacc cggtgaactg ctcggtggcg cgcgccctct
     7141 cggtggtggg ggagcgctgg tcgctgctga tcgtccgcga agcgctggac ggcgcgcgcc
     7201 ggttcgggga gttccactcc cgcctcgggg tcgccaggaa tctcctggcg acccggctcg
     7261 acaccctggt ggccgcggga gtgatgcgcc gcgtgccgta tcaggagccc ggggaccgtc
     7321 agcgcttcgc ctacgaactc accgagcggg gctgggcgtt gcggcccacg ctcgtggcgc
     7381 tgctggaatg gggcgacgca tacctcgccg acccgcaggg cccgtcggtc atcgtccgcc
     7441 accggcccgt cgacgacgcg agcccatgcg atgagccggt caaggtcgtc ctcgaatgca
     7501 ccgctgggca cagccacctc gccccggaag acgtttgccg cacgcccggg ccgggtgcgc
     7561 gcttcgtgga aggctcctga aaacccggga tcgtacttgc cgggctcatc gcgagaaatg
     7621 cgatccaaat aggggaaccc acgcctgtgt tacgaggcaa aggttgcctg acgtggcaca
     7681 gggtgggccg tgcccggccg gcacgggcgt ggaggacctc gctgtaggac acggcattgt
     7741 tctctgttgt cgggtttgac cgccggtttg acgaacccgc cggtaaccac tcgtcaccgg
     7801 tggaagtctg ctcgttccaa ccaagcggtt ggaacggtcg gttcccggtt tgactgaccc
     7861 agcggcgaga cgcaggctga atcaaggagg ggacgctccc ataggcgcac catgtgcgca
     7921 cggtgcgaac agcaatggct cacgggaagg ccgcgtgacc atgactccac aaacagaccc
     7981 gagtaagccg cacgtcgaac acgaggacaa accctggacc atcaacatcc ccgggcatcc
     8041 tccacgcagt gattcacccg agtatgtggc atcccgcaag cagatgcaca aactcgtgga
     8101 cagcttggac cacccgttct acggaccgga accagttgag gaccaccacg gcggcggcct
     8161 ctgggtcaag gacgaccagg gctggttcat ggtccgcaac atggccggca tcgagtggtc
     8221 cgcgcagttc tgcgccgacc ccgccaaggt cgacctgctg cgccagaacg cgcggcggct
     8281 ctacgcgggc ttccccgacg ccgtcgagga actcggcatc cgggaactgc tggacacgcc
     8341 catcacggac gccgacggcg tccagcggtg gaccgattcc atctgcaacg ccagcgtgcc
     8401 cctggccaag aaggaccaca gcgccgagct gccgaagggc ggcggcgtcc accactaccc
     8461 gagtccgatc accgagatcg gcttcttcaa gagggacgat ttcatcctgt gggtcacgga
     8521 cgacgcgggc gaaccggtgg ccgtcgcccc ggtggaccga cggggttcgg gggacgggcg
     8581 tgtgaacgtc ctgttcgcgt ccgaacagtc ccccctccac gcggaactgc acaaggccca
     8641 ggccaagggc caggcactgg tcctcgacgc cggccatgcg gtggcccggg ccgccttcgc
     8701 gcgacaggcc tgacctggtg gtgtccgggg acgcggtggc ggcgtcaatg gtgcgtggcg
     8761 tactggaaaa tcagtgaacc cttttcatcc tggctcttga agggtgaaac gtgcgggtca
     8821 ggtggggtaa cacagcaggg cccctcgtcg ttggcgtggt gacttcactc atcacaccgg
     8881 catccgaggg gccctgttgg ttccgtattc ttccatgctt gatgtcccgc atgagctcgt
     8941 tgagcatgtc gcgtggctga tccatgcccg tcggcaggag ctgaagtcgc cgtggaggag
     9001 actgggctgc ttcaggcagg ccctgctggt gctcgcccat ctgcggaaga atgagacgtt
     9061 cgcgcaggtg gcgggtggct tcggcgtctc cacgacgaca gcctggcgtt acgtggacga
     9121 gaccatcaag atcctggccg cctgggcccc gggcctgcgc gaggctctcg ccggcctggg
     9181 tgaaggagac ttcgtcatcg ttgacggcac cctgatcccg accgaccgta tcgccgcgga
     9241 cgagccgtac tacagccaga aacaccgcaa gcacgggatg aacatccagg tcgtcgcccg
     9301 cccggacgga accccgctgt ggttctcccg cgcgctgccc ggacgcaccc acgacctcac
     9361 cgcagcccgg gcccacggca tcctccagac ctgtctgacc agggagatcc tcgtcctggc
     9421 cgaccgggcc taccagggcg ccggcgccac cgtccgcacc ccctactacg gccatcgtga
     9481 actccccgcc cactaccaac ggttcaaccg cgtccacgcc agactccgag cgcccggcga
     9541 acgcgccttc gcccagctga agcaatggcg gatcttccgc aagacccgct gcagcaccaa
     9601 ccgcatcgga accatcgtcc aagccatcca taccctgctg atctgcgaaa acagaggatg
     9661 aaaaaggctc agtgacccat cgtcaggcga agccgcgagc gaccaggtac gcgatcgacc
     9721 aggtacgcga cgaggatcag cgcgggcagg accggtgccg tctcggcggc cggaagcatc
     9781 tcggcgccga cgtgggtcat ggcctcgccg ccgaccccct cgagcgcgat gtcaccgctg
     9841 atgcggcccg gggaggaggt ctccacgctg acgtccagcc cgtcggtacg tcacccacag
     9901 gcccagccgc atcgggccat cgcccaggtc gcccaccgct tagctcgaca agtccccgtc
     9961 gacgccttcc gctcgacgcc tgcaacgaac cgggcggaag tcagtcggct ttctcctggc
    10021 cctgccaggg ggtgccgttg tcgttggcat atcgcagggc gtcgtcgatg gctccggcag
    10081 agcgctcctc ccggccgtat ccgtaaatgc gtggcggctc gtacggggtg ccatcggggt
    10141 cgacgtaggc catcttcgtc ttgatcttga tctctttccg gccgtactga gggatgacga
    10201 acccgccgta gccgtaccgg aactgccggc cgatccggtc gtaccagttc tggagcccgg
    10261 cgatctggat tcccaggtgt tgtacgtagt tctctactgc cgcttggtgg gggccgaaat
    10321 cggggaggca ctgctggagg gaccatattt cctccacgtc ccggttgtgc atggccacca
    10381 cttcgtcgac ggcctgctgg aggctcacct ggcggtggtg gcggacgctc aggatctggc
    10441 tgaccacctc gttctgcccg agggcgagtt ccttgtgcag ggagctgatg tcgttctgaa
    10501 gggcgatcac gcacgcctga aggtctctga gccgctggac gaccggatgg ttgaagacgt
    10561 cgcccggcag cagcacaccg gtcaccggct caatctggtc ggcgaaaggc cgctggccga
    10621 tggagtgcat gcggatcatg cggcagcggt ggatcgatgg gtagatgccc tgcctgcgaa
    10681 atgcgacctc ctccatcagc ccgtagtgga tgtactgcca gtggctgagc gccatccggt
    10741 cgatccagaa ctgcggcacg taccggcgga actcctccct tgcggcggcc agctgccgca
    10801 gcaggccgag ttcccctggc ctgggatcgt cacgaccggt catgacctga tagatgcggt
    10861 ttcgcagcgg ggcgatctcc tccgccgggg tgaggtcgaa gaagtcgtcc atcagcgtga
    10921 tgtggttcat ccaccgggcg gccgggcgca gtcggtcgat gtcgttggcg gtcgggaaca
    10981 tatacggggt gacccgggag agaagctgct tgcggtagcg ttcccggtcg gccggatccg
    11041 ggaaaacgtc cgcgtagtcc tcgtcgtacc agcggaaggt ctcctcgtcg agagcgtcgg
    11101 ccagcgggct gtcgatggtt ggccacgggt aggtcaggcg ggggatgacg agttcctcgc
    11161 cggtatcgga ctggccgggg gcggtcgggc cttggtggtc ggtgctggtc acgtcgggtc
    11221 ctttccggcg gtggcgcaga gggtgtcctg gtcggggtag tactcggggt cgtagcggtg
    11281 gatatgtttg tcgacgcctc gccagccgga tatcacgaaa ctgaagtggt ggatgtgctg
    11341 ggcgaccggg tccgaccatc tgccgaagtc cggaaggtct cgctgaaggc ggacgaattc
    11401 gtccagttca cggtcgtgga tgctgaacag ctcctcgcgg gcctggtcga tgcagatgcg
    11461 gtggtggtgc gccaggacgt tgatgaagtt cacgttcccc atgccggtgc gcatgtcttt
    11521 gtcgtaggac tggaattcgt tgaaccagcc ggtgatccgt acggtgagcg atttcagccg
    11581 ccggaccacg gggtggtcgt ggatcccctc cggcagcacg gtgccggtct cgatctcctt
    11641 cagggccaga aacgggtgga tcatcagcgc cttctcccgc atggccatgt actcctcgat
    11701 gcccgggacg gtgtcggcgg cgaggtgtgt ggtctcggct tccaggccct ggaagtacag
    11761 gtcgaggtca tcggcccacc gtgccaccga ggtgggcggg atgaaggcga gggcttcggc
    11821 gcggatctgc gcgatcgccc gggcgagcgg cacccccgcc tcctgcggcg tgatctcgcc
    11881 ccgggcgacg gccaccgtct gatgccgcag gtgctgcacc tggtcagggg aggcgtgctc
    11941 gtacacgtca tcctggtaga gggagaacag catcatccgg gccagcggga tcagacgctc
    12001 ccaggtcgcc gacggaaaga agaacgccgt catgtaggcg gtccggacct gcttgaaccc
    12061 ttcggcgatc tcgggcggca cgatgcccgc ccactcctcg tcgatccaca cccggtcggt
    12121 gtgctgctgc agcgcctcgg catgagggtt catcaggctg ggaaacgggt aacgcagcct
    12181 ggccatcgtg gtcgaatcca tcatgtcgtc ctcaccatgg cgtcgttgac ttcgagggcc
    12241 gccctcggcg cggtcgggaa accccggcgc ggtccagacc cgctcgatcc gcgggtgcct
    12301 ccttggccat cggcccgctc cgcctgcaga tcgttcgacg tcgtgtgacg tgcggccgcc
    12361 ggctgtactg cgtgatcctt gcggtggtgg tcatgacgtc ctcgcggttg cggcgccggt
    12421 gagcttgcgc agggcggcgg tggcggcggg cggaagccgc gcggcctcca ggacgcgcag
    12481 tgcctgtgtg cggcggatga tgatcatgtg ttccgcctcg gcccgggcgc cggtggcggt
    12541 gagcacccgg cggatgcggt cggccccggc gtcgtcgagg tccgggttgc cgagcagcgc
    12601 gtccaggatg tgccgctggc tgggagtggc gcgctcaagg gccagggcca ccaggacggt
    12661 gtgcttgccc tcgcgcaggt cgtccagcga cggcttgccg gtgatctgcg gcttgccgaa
    12721 gacaccaagg aggtcatcgc ggagttggaa ggcctcaccg accggcaagg caaaggcgct
    12781 cagcgcctcg cgcaccgcaa gcggggcacc ggccatggcg gcgccgatgt gcaggggccg
    12841 ctcaacggtg tacttggcgg tcttgtaacg cgcgatccgc agcgcgtact caacatcccc
    12901 ggtggggtgg ccggcggcgg tgacgtccag gtactggccg tacatcacct cactgcgcat
    12961 gacatcgatc agcggtagca cggcaccgag ttgacgggag gtgaggtcga cggtgggcag
    13021 cagttcgtcg gaccaggcca gtgccaggtc gccgacgagc actgccgtgc tgacccccag
    13081 gtgtcgggcg gccgtcatgc tccgcccctc tcggtggtgc tgggcgaggc ggcggtggac
    13141 ggtgggggcg ccgcggcggg tggcggcgcg gtccatgacg tcgtcatgga tgagagcgaa
    13201 cgcgtggaac atctccagcg acgcggccgc tcgcacgatc gtggtggtgt cgccgtggcc
    13261 gccggcggcg caccagccgc agacgcacag cagcggacgc aggcgtttgc caccggacgt
    13321 aaggaaccgt cgcaggacgc tgatggcctc ggtgggcatg ccctctgagg ctgcggcgcg
    13381 cattttgcgg tcgaggaagc cggtcaggca ggtatcgacg gcttctctgg tcccggcgag
    13441 gtccaccgcg ggagtgaggg gcggtgtcgg ggcgctcatg acggtgtttc cccttgattg
    13501 tccttgtgtc cggccaggag gagggtctga cccgggctgg tggaagaaga ccttcggccg
    13561 accggcacca cggggtcgct gccggtcggg cccagagtcc ggccagagca acatggttgt
    13621 ccacgagagg tgcgctttcc ccgggttgaa ctccggacca tgcgtgttgc tgccgtagcg
    13681 gttaatcaaa atgtcgattc cgctgtgcgt gctcgcatgt gcccaggcct accagtaccg
    13741 ttcttttgcc gggcctaatt tgcggggttt tgcccccgtg ggaagttcta ccgtcggtgt
    13801 cgaccttgtt ccagtgcgca acattcgcat cgctgcaatc agcaggctgc tgccgagtgc
    13861 ggccacaccc cggcccggtg cctccgacgc ttgcaagtgg agccaggcag gttagtaatt
    13921 gttatccggt gacccagagc atgggaacgc ctcattcccg ccaatcgcgt agcgatgccc
    13981 cagtagttgg tattgaaagt gaccgttcga taggggtgag acttggccgg ccgatggagg
    14041 acgcggcgcg catcgcggtg gagacggtgc gggagacgga gacgtcggtg gaggaggtcc
    14101 gcttcgtctt cgcgggctgc tgtccaacat cgccgcctgg gacgcgacgg ggcacagcga
    14161 caactgcggc aaccccgact tcgcggtact cagcgacacc acctgcatca ccgagggcat
    14221 ccaccacggg cactgactcc tggtctcact cccggcctca gaacctgccg gatcgccggg
    14281 ggaagtagtc ctcgagtacg ccttcgcggt ggacgtcgag cgtggcgcag tgcagtccgc
    14341 cgccgaaggg ggccacgtcc cagaacggca ccgggacgac ctcgaagccc agccggtcga
    14401 gctgttccat ctgtgcggtc tcgctcgctt ccacgcagac cgtcccgggg tccagcacca
    14461 gcacgttcat cgacagccag cggctgcacg cggacagggg tggcggggtc tgccgcccgg
    14521 gggtggcggc ccggacgacc tgccagtcgt tgatcttgaa gtactgcagc aggtcctcgt
    14581 cggcgggccg ctcggcgcag tgcagcacga gccccgggcg gagcggcacc caggtggcgt
    14641 cgatgtgcat ggggtggagg ttctcgaacg tcaccccgtg tacgcggtgc tccggcaggt
    14701 gctgccggag ccagcggatc ccggccgcgt tcgtggcgag ggactgctgg acgaacaggt
    14761 ccttgccgca gcgggcgatg tccgcggcgt cgaagagcgg ttcggcctcg gtcagcacga
    14821 gctccccggc cctgacacgg gcgatctgct cctcgtacgg cagcgcgtcg tactcgtccc
    14881 ggaagcccgg ccggtaggac gcctcggtca gccggggctt gggggccgcc tcccagcgca
    14941 tgccggggtc ggcgcggtag taggactcga tcagcggccg gtgtgccagg tactcgaacc
    15001 agcggctgcg gaacgacatg gtcgcctcca gcagctcgtt cccgatcacc accaggacgt
    15061 cccggaccgg catggcaccg aacatgctct gctgcgacca ctcaggggtg gcgaccggcc
    15121 ggctgaagtc cagcggccgg ggccggtcga cccggatgcc gcgtgactcg aggacgtggg
    15181 cgaggttgtc cagttgctcg ttggccgccg ccgtcatctc ctcgggcaac ggcccgtacg
    15241 tgccgagtgg aaagccgtcc tccggccagt cacggacgac cgccgactcg ggcgcctgca
    15301 ccatggtgcc gtccgcccgg ccgacgacga cgtgcttcag cggatcccac tcgttccagg
    15361 aaccgacctt caccgatcct ccccttgggg gcgccgtgta cggcccgctc tccgaaagcg
    15421 ggaagcggcg aggagacaca gtctggcgtc tccccggccg cggtacgagg ggacaggccg
    15481 gggcgcgtga ggtgctgtcc ggagagcgcg tgccctctcc ggacaggcgg gcatcaggga
    15541 cggagcagta cgcccacggt gccgaacgcg tacgaggccc ggtacagctc gtcgccccgg
    15601 aaggcggcga cgtagccgtt ggtccgcgtg cccgcgctcc tgacgtactt cgaactgacc
    15661 cgggcgcacg gcctcagccc tttccgggcg gcccggcgca ccaaagcccc cggcggcggc
    15721 gcccacctga tgcgcaccgg cctcctctgc atcgccgccg gccttctcac gggaagcctc
    15781 ggcggcggca ggcccacacc cctgtggctg aacgccggct cctgcgccct gaccggctgc
    15841 ggcctgggcc tggccaacgg cgccgcgatg acgacggtcg ccatgggcac atcaggcgcc
    15901 acgggcgcca cgggcacacc cccacacctg gcactctgct cggcggcccc ggccctcgcc
    15961 ctgaccgccg tcgccctcac ccgccgtggc gggggactgg cgcctcttct cccctcgggg
    16021 gttcgggcgc tgacgctttc ggcgagcggg cgtgcgaagc gttcgccgcg cgggtgggat
    16081 gaccgatggg gatggcccgg aattcccccg gaccgcgcta ccgcgctgcg cttttgatgg
    16141 ggagtcatgt gtcgcggccc tcttccggcg aaaggcgtcc gcgtccgaaa cggtcggatt
    16201 cccgtagaag tccgcaagat ttctgcgggt cagccgcagg aaattgaatt tttgaccgtc
    16261 cttttcggga atttcgtcgg ttgacaaggt tggccactac atcggaaggt gaacgcattc
    16321 actggggcgg caaaacagcc atgttttcct cgcgcccgag aggctatgca gaagaggggg
    16381 gtcccgtgcg agtggtcctg gccgaggatc atccgaccgt tcgagccgga acccgggcgt
    16441 tcctggagcc cgagggcttc gtcgtggtcg gggaggccgc ctgcgaacgc gaggccttgg
    16501 aggtcgtttc cgagcagcgg cccgatgtgc tgatgctgga catgaggctg gagtcggggc
    16561 tggcgctcaa ggtcattccc cagttcctcg ccgccgcgcc ggggatggga attctcgtgc
    16621 agagctgcta tgaggaccgt gcgatcattt gcggcgcgct ggccgccggt gccgcgggct
    16681 atctgctgaa gagcagtccc gtgtcggagc tggtcctggc ggtacggacg gtggcgtcgg
    16741 gaggacggta cgtacagccc tccctcggtg ccgggctggc ccgtgaccag ggccgggagc
    16801 cggagctgca actgcgggag cggcaggtcc tgggcctgct ggccgaaggg cacaccaacc
    16861 gtgaggtggc cgcgcggctg acggtcagcg tccgcacggt ggagagcgtc agggccgctc
    16921 tgcgtgcccg gctgggcctg gtcaccaggg ccgagctcgt cgcgtacgcc cggcagaacc
    16981 gctccgccga tgtgtagcgg gaccgccggg ccggccaccg cacgacagcc gctcgccctg
    17041 ggcgcgctca gcggcttctg catcgcggtc accctggtca gcgtcgtggc ctacgcggcc
    17101 aacttcctca cccacgaccg gctgccgccc cggacgatct cgaccccgag catcgccctg
    17161 gccaccggca ccctcgcact gctgacctgc gggatgcggc gggcccgccg tttgctgatc
    17221 atgatctgct gcgggttcac ggccctgagc gtggaccggc tggcccattc cgcggcgacg
    17281 gaccacgtgg ccctggcgtt cctgctggcg gcatcggcgt acgccgtccc ggcctggccc
    17341 gaggtgaagg tgctcctcag ccggggaagg gccagtgcca tggtggagcg gcaggagcac
    17401 cacgcgggcc tgctcgcggg cgagctgcac gacgaagtcc tccaactgct ggcactgacc
    17461 cggcggcggc tcgacgcggc ccgcgcgctg gacgaccccg acgcgctgcg cgcggcgatg
    17521 gaggacgcgt cccgcaccct cgacgaacag gccggcacgc tgcgccgcat catcgccacc
    17581 gtgagcccgg cggccgtcca ggggctgggg ctcgccgagt cggtcacctc cctcgccgca
    17641 caggtcgccg ccgagaacgg gctcgtggtg gacgtggagg tccagggcga ccggccccat
    17701 gtgtgcgcgg gggagaacgg tgtgaatctc gccgtctacc gggtcgccca ggaagcgctc
    17761 accaacgtgg tcaagcacgc cgacgcccgg cacatcaccc ttgccctcgc ctgtcgcgac
    17821 gagggcatca gcctcaccgt caccgacgac gggcgcggtc tcggaccgaa cccgccgaga
    17881 gtcaccgagg ggtacggcat gcagggcatg cgctggcgct gcgaagcgta cggcggcacc
    17941 ttcagcgcca ggaccgcggg cgccgccggc acggtcgtcc gggccgtgtt cccgctgcgc
    18001 agctgccgga gagcccggtc gtcctagccg gccggccggg cgtgcgggcg ccggcgtggc
    18061 ccctggcccg tacgggccag gggcgggatc aggccgagcg gcgtcggcgg tacaggtgga
    18121 ggaccgccgc gcccgacact gtcagggccg ccgcgccgga ggcggccggg agccaggggc
    18181 gggaaggggc ggtggcggcc tggtcctcgg cgagggcgta gccgcccgcg aggcccttgc
    18241 ggtcgtaggc cgagccgggg agcttgtcgc cgtagcgctt ggcgacgagc tgctggtact
    18301 ccgcgagcgg gacgcgggcc ttgccctgca gggccgtccg ggcttccttg ttgagaggct
    18361 cgacggagcc gctgccggtc agccggtacc aaccgtggat ctgcggctcc atgaaggtcc
    18421 gttcctggtc cgtgccgcgt tcggcggcgc tgatgtccgt gtcgccgtca cggatgccgg
    18481 ccagttgcca ggcgctgccg ccttgtcccg gagcgagcag gacggcggcc tgacggccgt
    18541 tggcggccga gacgcgggag gcgaggtagg acagccgcag cgccgcgccg gcggtggcct
    18601 tggccttgcc ggcgacgaac tcgggcgaca gctcgtagaa ggggaccggc ttcttgaggt
    18661 cgaagccggg tgcggtggcg ggcgaccgct cggggctgcg cggggcgccg gccacgccgc
    18721 cgtccgcgcc gccgccgccg gcctgggcgt cgccgttcgg gtcgtcccgc tcggcggcag
    18781 ccgtcaggaa gcgggcgacg gtgtcacgaa gctggccgga gcgcagcacc ttctgggcgg
    18841 cggtgatgtc ggtcgccgcg ggggtggtgg gtccgtcagc ggcctgcgcg ggaacgactc
    18901 cgcagagggc ggcgacggca gtggccgcac acagggtggc ggcgcgtcgg gttgagtggt
    18961 gcatggtggg tcgtttcctc cggtcgttct agccgtgtat gccgacgcgc gtgtgggtcc
    19021 accggaagga gttgtttccg gagtaggtgg agtagttcca ccaggtatag gtcttcgtgg
    19081 tgggccaggg gtcgccgacc gcgatcatgc tggtggtgct gtcgtagccg tagacgacgt
    19141 tcatgtggcc gccgccggag ttccagccga tacggacggc gaacgggcgc ccgttcgcga
    19201 tctcggtccg ggtctcgccg aaggaggcgt tgcggtacag gtcgctgcca ctgttgcgga
    19261 agcccatgtt gcggagggcg ttggccatgt cgccgagggt ggcggggcgg ttgttgcagt
    19321 ccagccggtt gttctgggcg gccaggcggc agaagtcgta ctggtcgtag cggttgtagc
    19381 cccagaagtt ggctatggtc aggccggtgg cgtcccagca ccactggtcc ttgacctgct
    19441 tctgcatgct gatgtcgagg gccttccggc cggtgggatt gccggtgggc ctgtcagtgg
    19501 ggttaccggt gggcctgtcg gtgggccggg tggaggcgca gagcggtagc cccccggtgt
    19561 tctcccggat gaacgcgtcg gcgatgtagt acttgccgga ccagatccag cgggagttgt
    19621 tctcgacgac gtcgccggtg gtgcgacagg tcatcgggat ctggtcgccg acccatgact
    19681 ttccggtgat ggcggctgaa agcgacggct gggaccgctg gttgacggtg ctgaaattgc
    19741 cccggccacc ggtgaccgag ccggtgacgc tggcctgggc ctggggggag aggctcagca
    19801 ggagcccgcc cgacaggacg gcggcgccgg tcgtggccag aagcaccttt ttgcgccgtg
    19861 acgcgggggc ggcatgtgtg tgcgtcgatg tgcgggttga tccacgaaat atgtgcatgg
    19921 ggtttcttct cttgctgatc ggcgaggcgg atcagtactg gatggtgtgg ttgtagaggc
    19981 cgtcacgggc cgccgtgacg gccacggtga gggagagagg agggcgctgc cgcggtcatc
    20041 aatcagtggt gaacggcagc gccttgatcg acaactcgcc gagacattac gtcatatgga
    20101 ttacgcatgt catattcggc atgcaactac acgacacaaa aggcgaatag atgcggtgtc
    20161 acctgtggtt ttgcgggaaa cccgcaatgg gtgcggtaaa cccgcaatag gcaaagggaa
    20221 ttgaggcgcc gcctatcggg cggtccgagc gccggcgcgt cagtggcgcc ggggcctgcc
    20281 gccgccggac tggtccttgt caccgggctt cgtgtcaccc ggcttcgtgt cgtcctgcgg
    20341 agtgcgcggc tgggggatcc gtatggctcc cttgccgtgt gcgagttgca cctcgcgccg
    20401 cacctggggc atcggcaggc gcacagcgag cgcctggacg ccgccgatct tcagatacgg
    20461 catgacccag ccctccaggt ccactcccgc gaacagcttc cagtcggcgt cggccgcggc
    20521 cctgccctcg gtcgacgcgc cggccccgcc cttgacctcg gtgcgcacgt acggcgcggc
    20581 gacgtcgccc ttcacgccca cgctgccgta gagaccgagg ttcgcctcgg tgccgaaccg
    20641 gatcttcgcg tcagccgcgg ccgacgcgct cgccttcagc gtcccgggcg tgaagccggc
    20701 cttggcctcg ggctgccagc cctcgcgcag actgaacgcg gagccgagag tgaagtctcc
    20761 cttcaccggg tcctgctgga cgtcaaggct catcctgccg gccgcgtcga tcaggacgta
    20821 gcaggtgaga tcgatgttga cggtgaccgg cagctcgccg atgtagaagg tcgggttggc
    20881 gtggaggacg acgaacggca ccctcaccgg cttgccgttc gtcgtgggag ccgtccgccc
    20941 cttgaaatgg aacgccgagg accagtcacc ggtcagccgc agcccggtcc ccgacgggcc
    21001 gtcgccggaa ccgcggccgt agtaattgaa gtcgacctcg ggtgcgagct ggacgaagcc
    21061 cttgaacgac gccttggtgg ggctttccac cccttccccc ttcgcgtcct tctccgtgtc
    21121 gagcgaggtg tcgacgtcga cgcgcaggct gccgaagggc agcttgaggc cctcgggtcc
    21181 ggcgtggacg ttgccgcgct cggcccagga gaccttcacc ccggggacga gcgaatcgac
    21241 cttgaagccg gacggggcga cgggcagctt gctcttgacc tcggtgtcgc ccagcacggt
    21301 ggagagatcg accggggcgg tacggacctc ggtgcccttc gaggtcgtcc tctccacctt
    21361 cgtgaccttg gccaggaggc cctggggcgc tccgggcacg ggtttgctgg cgacgatgtc
    21421 gcccacggcg acgggcttgc cctccgtggg ctgcttctcc gcgcccgtcg ccgacggccc
    21481 cggcgtaccg gacgcgctcg gggtgggccg cgcgagggtc tgggagatga cggcgcgccc
    21541 gctgttccgg tcgatggagt cgaccttcac cgccgacttc cgcgtcttga cgccgccgcc
    21601 cgccggaatg gccaccgcgc tgggttcgga tcccgccggg ggcgtcttcc cgaggaggaa
    21661 gtcgttgggg ggagcgctga ttgcactgtt cgccgtctcg tccgaggcgt cggtggagcc
    21721 gctccccaag ggtgagcagc cggccagggc gagcgagagg gaggtgagca gcactggtgc
    21781 cagtgccgct cctctgcgga ggttgcgcat agtggatcct cgtggattgg tgtgaggggt
    21841 ctgttgtccc tgcgagaggg ggcgtgggaa cacgtcacgt caggtcatgg gcggaacctt
    21901 tcgttcggca gggcctgtgg gcttacgggc ctgcgggtca cttcgccccg gccgccaggg
    21961 cctcgaggtg cgcggccgcg gccgcggcgc cccccgcggc gcggaacgac gcgcgcaccc
    22021 tcccagccgc ctcgcggcag ccgggttcgt ggaggacggt gtccagcgcc gtgcccagca
    22081 cgtcggcggt cgcccggttg aaccggaccc gtacgcccgc cccggcgtcc gtcacctggg
    22141 cggcgacggc gggctggtcg tcccggatgg gcgcgacgac gagggggagg ccgtgccaca
    22201 gggcctcgca cacggtgttg tggccgccgt ggcagatcac cgcgtcgcac cgttccagca
    22261 cggccagttg gggaacgtgc ggccggacca gcacccggtc ggcgaactcc ggcaccgtgc
    22321 ccgtcgggtc gacgatcacc gcctgtgccc ggtccggccg tccgcgcacc gcctgggcgc
    22381 acgcggcgag gaagcggggc gccacctcgg cgttggccgt gccgagggtg atcagcacgg
    22441 tgggcgtccg ggggtcgagc cggtgccagg ggaagtcgcc ggtggccggc cgggcggtga
    22501 gcgacggtcc gacgaaccgg acctgtccgc cgccgggcgg gaccggtccg gccagggcct
    22561 cggtgctgaa ggccagcacc agccggtcgg acagccgggg gtccgcggtg ctccgggggt
    22621 cgccgatccg ccgccgcagt tccccaatcc tcccggcgat ccaggcgtcg acctcgggca
    22681 ggccggacag cgaggtgaag cccgccgtgg tggtcgccga ggtggcccac accagcccca
    22741 gccgctcggc cacgaggccg ccggcgacgg cctgctggtc ggccaccagg acgtccggcc
    22801 ggaactcccc gacggccgcc cgcactccgg gcgccatgtg ctcggcgagc ggcccgagga
    22861 agcgttccca caggaacttg gagggccgcg cgggccgcgc ggcgccgacc ccttccgaga
    22921 tcgagcacgc ccaggccgcc ggcccggcag accgccgcta ccaggcgtgg atcgggttcg
    22981 ccgaacgggc tgacgcccag gattgtttct gtggacacgg gcactccgga gacaagaggg
    23041 aggcgagagg gaggcgagag cgaagcaaag ggtcgttggg ggggagcacc gggaccgcgc
    23101 gggagcctcg ggcacccgag gccggagagg gacgccgcga tcggtgccgg tgagggcggg
    23161 acaggacaag aggcgcgcga cctcgaaggt cgtcggaaac gcggcccgac tttcccggtg
    23221 gggcctggct ggatcattgc acggcaaggc gcgaagggaa tacctggatc ggtattgtcg
    23281 cgtgaatggt gtacatcaca ttcatggtcg ggtcgatacc ggttgcgggc ttcccgcaag
    23341 ggaattgtgg gaagcccgca acgggtgcgg aattaccgca agaatagtcc gtaccagtcg
    23401 aggtgacagg ctcaactccc ttgtaattac tgctgattga ggtagcttcg gatcggatgc
    23461 gaattccgct cgaaaactt
//
