LOCUS       NZ_CP034587            21023 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6836094
            Orig. end                         :: 6857117
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21023
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="37"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21023
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21023
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11023](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11023
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            2299..2751
                     /locus_tag="EKH77_RS30395"
                     /old_locus_tag="EKH77_30395"
     CDS             2299..2751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532219.1"
                     /locus_tag="EKH77_RS30395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30395"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_164737910.1"
                     /transl_table=11
                     /translation="MSGYEPGVHADRTARHGRPHLTLDIERVLSVSARQAIRAEFSFDP
                     RAPLIVCVEFGVEGGPRALWRIGRDLLRQGLRSRSGVGDIQIWPSNPENRATAWLQLTS
                     GDMAALFELPIPPLSEWLDHTYALVPAGHELSGVDWDVTTTDLLAG"
     gene            complement(2748..3212)
                     /locus_tag="EKH77_RS30400"
                     /old_locus_tag="EKH77_30400"
     CDS             complement(2748..3212)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669129.1"
                     /locus_tag="EKH77_RS30400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30400"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_126917429.1"
                     /transl_table=11
                     /translation="MMNRRLLLRTSSAAVAGALGAAALPDTVATAAEATPGPSARPIGG
                     SGPTDGVTRRLLQEHPSPAEGWEAVQTLVEIPRHKESGRHSHPGVEVGYIIRGDVLMEF
                     DDRPPLRLRTGDPFFIPEGAIHNARNVGTVTTMMLSTYVVDATKPLVTTY"
     gene            complement(3407..7432)
                     /locus_tag="EKH77_RS30405"
                     /old_locus_tag="EKH77_30405"
     CDS             complement(3407..7432)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963198.1"
                     /locus_tag="EKH77_RS30405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30405"
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_206279959.1"
                     /transl_table=11
                     /translation="MLASLVTLFTPPAPAQAVEDLDKRAITFNMQGGTRWETVRTNLIK
                     DADVVTLQEATTAPWDFTKNEVITDNLGDTAKTPTGLPSLKYRVYAQQWGERRKQGVLL
                     YLDILGRDAWGAGTGADTGDPETENNSQKSMAIWLRDAPDDLKDLKDRVKVFPAQDVGN
                     KWIRSRPAFGVKVGNTWYFDIHAASIRSGDTPNHHTVALIDTISRTMAGERWRALGDFN
                     SAAAPTRGRFPNTFYATKNGKPDGTPTTTQKSGFALDYMIASDQLKNLDVSTTGRNGGS
                     DHNPVRFTPRNTRACATDWSEPTRYNYDAAVWLAARAVEDACGPPPAVVSMGDSYISGE
                     AGRWAGNAPASAAGSAWGTDRAAVNCNGDESLCDHDASKVYGDTSYDKGGSGCDRSDSA
                     EIKGLTVDDVPLERRFNIACSGATTDNVTTTGFKGRRPQIDDLRDIARSNEVRLVVLSI
                     GGNDLKFADILQDCVKAYFYPSLFNKGCRGAKEKEFADGLDPARAKIVKSVEAIRNVLR
                     EAGQEDGSYQIVLQSYPNPLPLGRDYRDPENAPVPPANYSRYLSGGCPFLDADSDWAHS
                     SVVPRISAMLRGAANEAGVSFLDLQDAFAGHELCGRTTQQAGKDHKLSSPLPAERAEWV
                     RWVPYLVDGLKDLPWQAQGNQQEAIHPNHYGQLALSACLTKITAKLGPAPVASSCVGKP
                     SGAPGSVDGSVDNSTVLSKSNRRAPVAGLPDWSRAGYRAGEVLPAAASRTSDPTCRITP
                     SELEQRFKVRPDDGQDDTAGLQSAIDRIRESCTPGAGPNRLSVIELPKGRLDVSKQLAV
                     DASYLVIRGQGSDPDGGTRIVFRPDENTRYDKLTEKGERWNQGAMEHKCEFTTGNNVGS
                     GGWIWPGRGLFRVQTREVAEKYLKICGYPSKIPENRRDLFEGSVNQHWESGVAVAGSPA
                     DAKYAAHQGDRVIQLDPKAKTDAFKPGGDLWVGAANSLKFYQSQEVAGAAADDGRLENL
                     HMRQQVFTIASVDAARHTVTIDKPLEFDVPVDSTSDGSPPLGVNGKPYPSKVTALKMIS
                     DVGFEDFSFTEDINGLPKLGGGTYRLSPADAVHNYGNMAPEYAMHGIVFKWAADSWVRG
                     VRADMTGSHPVVTEVARNIQIEHNVFDGAWNKGKGGNGYLRGSRVWDSVYAFNTSRNLR
                     HFTFQWSASGNVAIGNDLDSDLNLHGGWEHRNLFENNTVHVPYNHSSGECTTNCGGEGG
                     AGDKGTWWPVYWAAGSKGIGWSGSTGPQNVFFRNTLTKQTTPGGPYEPYQPYADTSRVF
                     QFGSAAGDASVFQHLKGAGGPIQDWADNERHDYTGGDGVNASRADAGRSLFLRDYRS"
     misc_feature    complement(7409..7411)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7915..8484
                     /locus_tag="EKH77_RS30410"
                     /old_locus_tag="EKH77_30410"
     CDS             7915..8484
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020120274.1"
                     /locus_tag="EKH77_RS30410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30410"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_206279960.1"
                     /transl_table=11
                     /translation="MSSQAAAELRSRYVEQVASELEENRRRQEELAKKIELLQQEEALL
                     SDILNLAERYEGFADASRLPEQAQGEPAVAKAKRRSAAGATTRRSTPSGTASAGTRTKS
                     DAKGKPGRPLLGDSLMDLLTGHDEPRSAKELRDELLEKDPSRNPTPQVVRNTLESLVAK
                     GRVQRHKQQRAVMYTLVKPADDADAG"
     misc_feature    complement(8498..8510)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    complement(8500..8509)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.19"
                     /tool="antismash"
     gene            8589..9929
                     /locus_tag="EKH77_RS30415"
                     /old_locus_tag="EKH77_30415"
     CDS             8589..9929
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="EKH77_RS30415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30415"
                     /product="cytochrome P450"
                     /protein_id="WP_276319268.1"
                     /sec_met_domain="p450 (E-value: 1.3e-72, bitscore: 243.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGRLPLLGHLPQLAVKRVEFLQSVRTRGDIVRIFLGNRPVFILN
                     SPEAVHDVLLTQSRKFGKGLLFDVARPFIGNGIITSERDFHLRQRRALQPAFHRNSIAA
                     CVGTMTDIAEEQVSAWRPGEVIAMDVVMRRMMTVMLVATLFSTERPEGAAAVAELGEQV
                     AEHLTTVMRGVFVGTVLPAPIASSRVLGHRKYLAAAAALRELADTAVRQARQTQQAGQA
                     PTARGDLLSVMLAGTPGNPRGMTDVEARDELLSLLMAGAETTSTTLSWALHELGRRPEI
                     TRRMRAECDALPAGALPGAATLPFTDRFLREVLRLHQPSWLLMRRALEPVRVCGVELPR
                     GAELVYSAVTMHRDPAYYPEPLRFDPDRWLARTEKDLPPGAYVPFALGNRKCIGDHFAM
                     TEMLVVLRAIVSRWRPRPVEGHRVRPVVQALIRPNALPMRVSPWPAG"
     misc_feature    8601..8603
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9967..9981)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            10001..11023
                     /locus_tag="EKH77_RS30420"
                     /old_locus_tag="EKH77_30420"
     CDS             10001..11023
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="EKH77_RS30420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30420"
                     /product="pentalenene synthase"
                     /protein_id="WP_126917432.1"
                     /sec_met_domain="T1TS (E-value: 5e-62, bitscore: 209.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVDPGPPAPVQTPDPVPFPRRISPDFRAAHDRHLAWPKSFGFLS
                     SEAAEAHHLRGQFPLIAAMFYPNATGSELDLGVDQQSWYFLFDDALDEEWGRSPERVRH
                     LVGLVKEGTSGEASPLPLAGAFADMRRRSCQDMPEDWIQRSAAHWSSYLDHHVHEARSR
                     QTGAPMSLSTYLRVRRHTIGVAPVVDLAERLSSCVLPDHLYALPHLSVMREMTKTFIIC
                     DNDIVSLEKDTALGERNNLVLCLERDHGLSRAEAIDQALCRRAEALELFTGAHRALLGA
                     TATSHLDPAERDLLQRYCTEALRTTIRGAHDWHHASTRYHGQSAPPVPLTRPRSQDRSS
                     "
     gene            11035..12234
                     /locus_tag="EKH77_RS30425"
                     /old_locus_tag="EKH77_30425"
     CDS             11035..12234
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019434434.1"
                     /locus_tag="EKH77_RS30425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30425"
                     /product="cytochrome P450"
                     /protein_id="WP_126917433.1"
                     /sec_met_domain="p450 (E-value: 4.1e-21, bitscore: 73.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDHRPASFVASERDGTCPFDPSPDLRRMREEDGLPRLRVLHPVR
                     GEIEAVVITGYGDVRAAFADERLVTGNGIDPTLPRTLFNHPGFLPAYSGPEHARLRRML
                     TGSFTVRQVERLRPAIETIVADHLDAMAEQGPVVDLVEAFALPIPSLAICELLDVPYGT
                     RSMFQRCSQVIMDGTVDADRLVAASAELNAAMADIVARNRATPGDGVLGTVVRQHGAEL
                     TDEELIGFGTTLLVGGHETTATMLALSVLALLRGPDQLAALRDDPAVTGTAVEELLRHL
                     AIPAPLLRTAVTDVEINGHRIAEGEHVLLSPLTANRDPGLVPERPDDLDLRRRPVAQLS
                     FGFGAHQCLGQQLARLEMKIALPALLRRFPTLRLAVPEAALRFREGSTVYGVEVLPVTW
                     "
     gene            12423..13046
                     /locus_tag="EKH77_RS30430"
                     /old_locus_tag="EKH77_30430"
     CDS             12423..13046
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532196.1"
                     /locus_tag="EKH77_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30430"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_240667615.1"
                     /transl_table=11
                     /translation="MSTAQPARKRDAAATREAILAAAVVEFTEHGYAGAGVRRIAERAG
                     VTAMMVNRYFGSKQGLFTQAVARSFAPPTIVGDERADLAGAIAHTLTERTASDAERLDP
                     FLLLLRSAPDPEAADIVRRGVEANVGARLAGLLDGPDADVRAQLALALVAGTWLLRGVV
                     GTTALATADDARLIALLTDMLEPVVHEVGGTSAATGTGPDGTQG"
     gene            complement(13064..13864)
                     /locus_tag="EKH77_RS30435"
                     /old_locus_tag="EKH77_30435"
     CDS             complement(13064..13864)
                     /NRPS_PKS="Domain: PKS_KR (10-116). E-value: 1e-10. Score:
                     33.8. Matches aSDomain:
                     nrpspksdomains_EKH77_RS30435_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015794361.1"
                     /locus_tag="EKH77_RS30435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30435"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_126917435.1"
                     /transl_table=11
                     /translation="MNLNLIGKRALVTGSSAGLGEATARFLAAEGAGVVVHGRDARRTE
                     RVAREIREAGGTADVVVGDLADDDAAAGVARAATAGGPVDILVNNAGSYRHLTWAEATP
                     DEWRDTYDANVVSGVRMIRHLVPAMRERGWGRVVTIGGGLASQPMDAHPQYNATLAARH
                     NLAVSLARELKGTGVTSNVVSPGAILVEATKDFFTGIGPARGWGRTWDEVEPNAVQALI
                     PNDQERFGKPEEVAAAVAYLCGDHAQYISGATIRVDGGLIRSAF"
     aSDomain        complement(13517..13834)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS30435_PKS_KR.1"
                     /evalue="1.00E-10"
                     /label="EKH77_RS30435_PKS_KR.1"
                     /locus_tag="EKH77_RS30435"
                     /protein_end="116"
                     /protein_start="10"
                     /score="33.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="LVTGSSAGLGEATARFLAAEGAGVVVHGRDARRTERVAREIREAG
                     GTADVVVGDLADDDAAAGVARAATAGGPVDILVNNAGSYRHLTWAEATPDEWRDTYDAN
                     VV"
     CDS_motif       complement(13757..13834)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH77_RS30435_0001"
                     /evalue="7.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH77_RS30435"
                     /protein_end="36"
                     /protein_start="10"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LVTGSSAGLGEATARFLAAEGAGVVV"
     misc_feature    complement(13849..13863)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.68"
                     /tool="antismash"
     misc_feature    13936..13951
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.07"
                     /tool="antismash"
     gene            14358..15053
                     /locus_tag="EKH77_RS30440"
                     /old_locus_tag="EKH77_30440"
     CDS             14358..15053
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013775.4"
                     /locus_tag="EKH77_RS30440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30440"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_240667616.1"
                     /sec_met_domain="APH (E-value: 2.5e-16, bitscore: 58.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPAATRNCPHCDQPITIVALLATPEAIWRLPGRVVARLDRFNGQ
                     EIAERELAVARWLADNGVHTARPAVVDRPALVDGQPVTFWDELTPHRPGTAADVARLLK
                     QMHQLPPPASLRLPPLEPLTKPTRRIANAGILTTDDRRWLQDHARRLAADFAGLPAGLP
                     LCALHGDAWDGNDAVDADGTACLLDLENTCCGPPEWDLVSTSVKHRTTATVTAAAYEDF
                     CSAYSMDVT"
     gene            15327..15545
                     /locus_tag="EKH77_RS30445"
                     /old_locus_tag="EKH77_30445"
     CDS             15327..15545
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_30445"
                     /product="hypothetical protein"
                     /protein_id="WP_126917436.1"
                     /transl_table=11
                     /translation="MAGRGLTVIGPGLTSGIGGGLPGCSAEKATGVSPCEEIMGIASKA
                     YNEIQRYALTHEQDDQPRTHQELGDNR"
     gene            complement(<15745..16056)
                     /locus_tag="EKH77_RS30450"
                     /old_locus_tag="EKH77_30450"
                     /pseudo=""
     CDS             complement(<15745..16056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670434.1"
                     /locus_tag="EKH77_RS30450"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EKH77_30450"
                     /product="phosphoketolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRDVTTSAPATTLTDDELRALDAHWRAANYLTVGQIYLMANPWLE
                     GMYAETYPDVNRNAAGMERLFRQFSFPAAYPATSPPRPAGRSTRAGELGYSLSHAYGAA
                     "
     gene            16232..17044
                     /gene="ppk2"
                     /locus_tag="EKH77_RS30455"
                     /old_locus_tag="EKH77_30455"
     CDS             16232..17044
                     /EC_number="2.7.4.1"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ppk2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606682.1"
                     /locus_tag="EKH77_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30455"
                     /product="polyphosphate kinase 2"
                     /protein_id="WP_126917437.1"
                     /transl_table=11
                     /translation="MTDDDRPHRLSRPLYERELLRLQVELVKLQEWVRAERRRLVVVFE
                     GRDAAGKGGAIQRVVQRLNPRVVRIAALPVPTERERTQWYFQRYVGQLPAAGEIVLFDR
                     SWYNRAGVEHVMGFCTDEEYARFLRQCPVFERLLVEDGILLRKYWFSVSDTVQEQRFRD
                     RLADPTRRWKLSAMDLESITRWEAYSRAKDEMFAHTDIPEAPWYVVESDDKRSARINMI
                     AHLLSTVPYRDIPMPAIDLPPRPPSTGYQRPPRDRQTRVPDRAAELAR"
     gene            complement(17168..18397)
                     /locus_tag="EKH77_RS30460"
                     /old_locus_tag="EKH77_30460"
     CDS             complement(17168..18397)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.4"
                     /locus_tag="EKH77_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30460"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_126917438.1"
                     /transl_table=11
                     /translation="MTRRTVSHGHDPKGRAACPCGAEVIRADGCEAANEQFRGLLESAP
                     DAMVIVDDTGAIRLVNSQTEVLFGYNRHELLGRPVEVLVPGRFRDRHAAHRKDYAHNQQ
                     FRPMGAGLDLYGLRKNGHEFPVEISLSPLRTGEGVLFSAAVRDVTERKAAEAELTRLYE
                     QQRHVALTLQHSLMGTPPDVPGLLTASRYLPATQGAGVGGDWFDLVPLADGKVGVLIGD
                     VMGRGLEAAAVMGRLRSAANALARTGMPPHRLMEVLDAIVTDLPGQLVTCCYLVVDPGS
                     GEITLCSAGHLPVLLAAPERDVLPLPAPVNVPLGVSGFPHEQVTRTAPPGATLVLYTDG
                     LVETPGTDIEKQITALTTALGTALDKQQNLETQDLEAVADSVLSALLPRSAGDDDVTLL
                     LAQLPPRIVR"
     misc_feature    18571..18585
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    18696..18711
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(18697..19356)
                     /locus_tag="EKH77_RS30465"
                     /old_locus_tag="EKH77_30465"
     CDS             complement(18697..19356)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1286: Pentapeptide
                     repeat protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963545.1"
                     /locus_tag="EKH77_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_30465"
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="WP_126917439.1"
                     /transl_table=11
                     /translation="MRTRAPRDLATLPFAHRLNPFTGEIERSGTYEWLHFEGRTFDDAE
                     GSSSLFSESAFSSVTFNRGRFRRSRFDDVWLHTVRMVGTNLAETTWLDSECTASIFAGA
                     EVHGAEMRRTVFHQCKFDSANLRAATLKDVTFVDCLLRDVDFSGATLNGVCFPGSALDG
                     ARFDKATLTAVDLREATTLRIASGTGSLSGATISTTQLFDLAPLLAQHVGFTVKDD"
     misc_feature    19314..19327
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.87"
                     /tool="antismash"
     misc_feature    19524..19542
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    19525..19538
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    complement(19529..19538)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.85"
                     /tool="antismash"
     misc_feature    complement(19531..19540)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.58"
                     /tool="antismash"
ORIGIN
        1 cagccccggt ctggatcccc ggatccgtcg tctgatcctg gacgaggccc aggggaaccc
       61 gctggctctg ctggagctgc caccccatgt gacgcacggt ggccgggcag gaggcgaccg
      121 ggacgaatcg cccggacaca ccggcatacc cctgcccctg ccattgcccc tgcgccttca
      181 gcaggtttac ggcgcccgta tcgcggcact cggtgacgcc gtgcgcgcgg aactgctgcg
      241 cggtgccctg gacggcgtcg gagcgggcac ggcgaccgga cacggccgtg gcacgcgcta
      301 tcgcatgacg gacgccgacg aggcggcggc acgcggcctg ctggacatgg atcccctcag
      361 cggcgacttc gttttccggc accctctggt tcggtcggcg gtcgtccgga cggcgaccgc
      421 ctgccaacgg cgcgccgccc acgcggtcct cgcgcacgtg caccgcgagg acgtggaacg
      481 gcgcgccatc cacctggcgg cttccgcggt cgaccccgac gagcgggtcg cggcagcgct
      541 ggaggcggct gccgactccg ccaccctgcg cggcgcctcg ctgaccgccg tgtcctggct
      601 gacccgggcg gcggagctga gccggagcga cgaggaacgg tcccggagac tgggtgacgc
      661 ggcgttcgtc gccggccagg ccgggctgct ggaccgggcc cggcaactgg tccgctttga
      721 caccacgaca gggacgagcg aatccccggc ctcggtcctc acatcggcct acgtcgcgct
      781 gtacgaggac ggggacgtgc ggtccgcgca gcgtcacatc atggcggcga tcgagaacat
      841 ccgtgacggg ggagtgcggg aaccgaacga ggtactcacc cggttggtga accttctcct
      901 ggccatcagc cagtacgcga gcgacaagac gtcgtgggag cggacacacg agctgctcgg
      961 ctccctgggc gacctggtgt ccccgaactc ccgcacctac gaggacgcct ggagtgacgt
     1021 ggtgcgtcgt ggcaccggcg tgcacgagcg ggtggagcgc gccctcgccg atctccgcac
     1081 tctcgaaccg tgggagacca ccaacctggg cgtcgccgcc taccacgtcg acaccctcag
     1141 ccagtaccag ccgcacttcc ggcgcaccgt cgaccgcgag gtggagaccg gggccgtggc
     1201 gtcggccatg accatgctgc atctgatcat gctcgaccag atggcggtgg gggagtggga
     1261 cgaggccgaa cggaccggac agcgcaccct ggacctgacg atggcgcacg actacgcgct
     1321 gttcactcac cacacacacg cgtacctcgg cctcctcgcc gcgatgcgcg gacggaccga
     1381 aagcgcacga gagctccagg ccaccgtcga cacctgggcc cgcccccgcg gcgtcggctt
     1441 cctcacccag atcgccgatg ccatcggcac cgccgccgcc ctcaccgaag gcgactacga
     1501 agccgcctat ctccacgcca tcggcatcac atcccccggc accttcacct cctacgccca
     1561 ccaagcctcc cgcaccctcc tcgacctcgt cgaggccgcc ctccacaccg gccgcgccga
     1621 acaagcacgt cgccacgccc tcgccgcaca ccgcgccggc ctccccgccg tctccccccg
     1681 cctcgccctc ctcacctacg gcgccctcgc catgaccgcc accgaccccg ccgaagccga
     1741 cgacatgtac caccgcgccg aaacccaccc cgccgccgcc ggtttcccct tcgaactcgc
     1801 ccgcgtccgc ctcgcccacg ggatccgcct ccgccacacc caagggcgca aagccgcacg
     1861 ccaccccctc acgctcgccg ccgaaacatt cgaacgcctt ggcacacccc cctgggccga
     1921 acgagcccgg gccgagctcc gcgccgcggg cgcgcccagc tccacctccc cctccgcgga
     1981 gtgcctcgcg gcactgacgt ggcaggaacg ccggatcgcg gatctcgccg ccggtggcct
     2041 gaccaacaaa gagatcggcg cacgcatgca cctgtcaccg cgcaccgtcg gctcgcacct
     2101 ctaccgggtc ttccccaagc tcggcatcac ctcccgggcc gcgctgcgcg acgccctggg
     2161 cagtcgaatg acttaacgcc gccgatcgcc gaacgcggtc agggcctgat ttcggcggtc
     2221 aacttactta tgcgcggtgc tccgcagggg acgagagtgg gtcgggccag cttcccccca
     2281 ggtaaggacc cacgcgtcat gagcggctac gaaccaggtg tacatgccga cagaacggca
     2341 cggcacggtc gaccccacct gaccttggac atcgagcgcg tgctgagcgt ctctgcacgc
     2401 caggcgatca gggccgagtt cagcttcgac ccgcgagccc ccttgatcgt gtgtgtggag
     2461 ttcggcgtcg agggcggtcc gcgcgccctg tggcggatcg gacgggacct gctccggcag
     2521 gggctgcgct cgaggagcgg agtcggcgac atccagatct ggccgtcgaa cccggagaac
     2581 cgggcgaccg cttggctcca gttgacctcc ggcgacatgg cggcgctgtt cgaactgccg
     2641 ataccaccgc tctcggagtg gctcgatcac acctacgcgc tcgttcccgc cggccatgag
     2701 ctctccggag tcgactggga cgtcaccacc acggaccttc tcgccggcta gtaggtcgtc
     2761 acgaggggct tcgtcgcgtc gacgacgtat gtggagagca tcatcgtcgt caccgtgccg
     2821 acgttgcggg cgttgtggat ggcgccttcc gggatgaaga acgggtcccc cgtgcgcagg
     2881 cggagaggcg gtctgtcgtc gaactccatc aggacgtcac cgcggatgat gtagccgacc
     2941 tcgacgccgg gatggctgtg ccgccccgac tccttgtggc gcgggatctc cacgagtgtc
     3001 tgcacggctt cccacccctc ggcgggcgaa gggtgctcct ggaggagcct gcgcgtgacg
     3061 ccatcggtcg gaccggagcc cccgatgggg cgggccgaag ggcccggggt ggcctcggcg
     3121 gccgtcgcca cggtgtccgg cagggcggcc gcgccgagcg cgccggccac cgctgcgctg
     3181 ctcgtacgca gaagaaggcg tcggttcatc atcgtgtctc ttacatgtcg accgttcaca
     3241 cctgaaggca atcacgccct cgaaacacac acaaggttga aagtcggcca acgcacacgt
     3301 gtgaacaaat agatctcacc catatgccag ggagtcatac gaggcgcgcc cgcttccagc
     3361 gggccgaaat ccgctggaaa cgggcgcgca cggccacggg tcgaactcag gagcggtagt
     3421 cgcgcaggaa cagggaacga ccggcgtcgg ctctggaggc gttgaccccg tcaccgccgg
     3481 tgtagtcgtg gcgctcgttg tccgcccagt cctggatggg gccgcccgcg cccttcaggt
     3541 gctggaagac gctcgcgtcg ccggcggcgg aaccgaactg gaacaccctg gaggtgtcgg
     3601 cgtagggctg gtacggctcg taggggccgc ctggggtcgt ctgcttggtc agagtgttgc
     3661 ggaagaagac gttctgcggg ccggtggatc cggaccagcc gatgcccttg ctgccggcgg
     3721 cccagtagac cggccaccag gtgcccttgt cgccggcgcc accttcaccg ccgcagttgg
     3781 tggtgcactc gccggaggag tggttgtagg gaacatgcac ggtgttgttc tcgaacaggt
     3841 tgcggtgttc ccagccgccg tgcaggttca ggtcggagtc gaggtcgttg ccgatggcga
     3901 cgttgccgga agccgaccac tggaaggtga agtgccggag gttgcggctg gtgttgaagg
     3961 cgtagacgga gtcccagacg cgggatccgc gcagatagcc gttgccgccc ttgcccttgt
     4021 tccaggcgcc gtcgaagacg ttgtgctcga tctggatgtt cctggccacc tcggtgacga
     4081 ccgggtggga gccggtcatg tcggcgcgga caccgcgtac ccaggagtcg gcggcccact
     4141 tgaagacgat gccgtgcatg gcgtactcgg gtgccatgtt gccgtagttg tggaccgcgt
     4201 cggccggact gagccgatac gtaccgccgc cgagcttggg cagaccgttg atgtcctcgg
     4261 tgaaggagaa gtcctcgaac cccacatcgc tgatcatctt cagcgcggtg accttgctgg
     4321 ggtagggctt gccgttcacc cccagcggcg gggagccgtc cgaagtggag tcgaccggga
     4381 cgtcgaactc cagcggcttg tcgatcgtga cggtgtggcg ggcggcgtcc accgaggcga
     4441 tggtgaacac ctgctggcgc atgtggaggt tctccagtcg gccgtcgtcc gccgcggccc
     4501 cggccacctc ctgggactgg tagaacttga ggctgttggc cgcgcccacc cacagatcac
     4561 cgcccggctt gaaggcgtcc gtcttcgcct tggggtccag ctggatcacc cggtcgccct
     4621 gatgcgcggc gtacttggcg tcggccgggg aaccggccac ggcgacgccc gactcccagt
     4681 gctggttgac ggagccctcg aagaggtcac ggcggttctc cgggatcttg gaggggtagc
     4741 cgcagatctt gaggtacttc tcggcgacct cgcgggtctg cacccggaac agtccgcgtc
     4801 cgggccatat ccagccaccc gatccgacgt tgttgcccgt agtgaactca cacttgtgtt
     4861 ccatcgcccc ctggttccag cgctcgccct tctcggtgag tttgtcgtag cgggtgttct
     4921 cgtcggggcg gaagacgatc cgcgtgccgc cgtccgggtc cgagccctgt ccacggatga
     4981 ccaggtagga ggcgtccacg gcgagctgtt tgctgacatc gagcctgccc ttgggcagct
     5041 cgatcaccga cagccggttg ggacccgcgc ccggcgtgca ggattcgcgg atccggtcga
     5101 tggcgctctg cagccccgcc gtgtcgtcct gcccgtcgtc gggcctcacc ttgaaccgct
     5161 gctcgagctc ggacggggtg atgcggcagg tggggtcgga ggtgcgggaa gcggcggcgg
     5221 gcagcacctc accggcgcgg tatcccgccc ggctccagtc cggcagtccg gccacgggag
     5281 cacggcggtt gctcttgctc agcaccgtac tgttgtcgac acttccgtcg acggagccgg
     5341 gagcgccgga cggcttgccc acgcaggacg aggccaccgg ggccgggccg agcttcgccg
     5401 tgatcttggt caggcaggcg gacagggcga gctggccgta gtggttgggg tggatcgcct
     5461 cctgttggtt cccctgggcc tgccagggca ggtccttgag gccgtcgacg aggtacggga
     5521 cccaccgcac ccactcggcg cgctcggcgg ggagcgggga ggagagcttg tggtccttgc
     5581 ccgcctgctg tgtcgtcctg ccgcacagct cgtgcccggc gaacgcgtcc tgcaggtcca
     5641 ggaaggacac cccggcctcg ttggcggcgc cacgcagcat ggcactgatc cggggcacca
     5701 cggaggagtg cgcccagtcg ctgtccgcgt ccaggaaggg acatccgcca ctcaggtacc
     5761 ggctgtagtt ggcgggcggg accggcgcgt tctccgggtc gcggtagtcg cggccgagcg
     5821 gcagggggtt ggggtaggac tgcagcacga tctggtacga gccgtcctcc tgcccggcct
     5881 cgcgcaacac gttccggatc gcttcgaccg acttcacgat cttcgcccgt gcggggtcga
     5941 ggccgtcggc gaactccttc tccttggcgc cgcggcagcc cttgttgaac agggacgggt
     6001 agaagtacgc cttgacgcag tcctggagga tgtcggcgaa cttcaggtcg ttgccgccga
     6061 tcgacagcac gaccagtcgc acctcgttgc tccgggcgat gtcgcgcaga tcgtcgatct
     6121 ggggccgccg gcccttgaag ccggtcgtgg tgacgttgtc cgtcgtcgct cccgagcagg
     6181 cgatgttgaa acgccgttcc agcggtacgt cgtcgaccgt caggcccttg atctcggcgg
     6241 aatccgatcg gtcgcacccg cttccgccct tgtcgtacga cgtgtcgccg tacaccttgg
     6301 acgcgtcgtg gtcgcacagg ctctcgtcac cgttgcagtt caccgctgcc cggtcggtgc
     6361 cccacgccga gccggccgcg gaggcggggg cgttaccggc ccaccgtccc gcctcgcccg
     6421 aaatgtagct gtctcccatg gagacgaccg caggaggcgg gccgcacgcg tcctccacgg
     6481 cacgcgcggc gagccagacg gcggcgtcgt agttgtagcg cgtcggctcg ctccagtcag
     6541 tggcgcacgc gcgggtgttc cgcggggtga acctgacggg attgtggtcg gaaccgccgt
     6601 tccggccggt cgtcgacacg tcgaggttct tcagctgatc gctcgcgatc atgtagtcca
     6661 gtgcgaagcc gctcttctgc gtcgtggtgg gcgtgccgtc gggcttgccg ttcttcgtcg
     6721 cgtagaacgt gttggggaac ctgccgcgag tgggggcggc ggcgctgttg aagtcgccca
     6781 gggcccgcca tcgctcgccg gccatggtcc gggagatcgt gtcgatcaga gcgacggtgt
     6841 gatggttggg cgtgtcaccg gaacggatcg acgcggcatg gatgtcgaag taccaggtgt
     6901 tgccgacctt cacaccgaac gccggacggg acctgatcca cttgttgccc acgtcctggg
     6961 cggggaagac tttgacgcgg tccttgaggt ccttgaggtc gtcgggcgcg tcccgcagcc
     7021 agatcgccat ggacttctgg ctgttgttct ccgtttccgg atcaccggtg tcggcgccgg
     7081 taccggcgcc ccaggcgtcc ctgcccagga tgtccaggta gagcagcacc ccctgcttcc
     7141 ttcgctcacc ccattgctgg gcgtagaccc ggtacttcag gctgggcagc ccggtcgggg
     7201 tcttcgcggt gtcaccgagg ttgtcggtga tcacttcgtt cttggtgaag tcccagggag
     7261 cggtcgtggc ctcctgcagt gtcacgacgt cggcgtcctt gatcagattc gtcctgacgg
     7321 tttcccagcg ggtgccaccc tgcatgttga acgtgatggc gcgcttgtcg aggtcctcga
     7381 ccgcctgcgc cggcgcgggc ggtgtgaata acgtgacgag cgaggcgagc atcgccgcgc
     7441 acagggcctg cgccgcggcg cttgcccacc aaggtctcgg tctgcgccgg gacccgcgtc
     7501 ccggcgtgcg tatggacaac tgtccgtctc tctttcccgt ccgccgcggc ccgtcacgag
     7561 cccggaaccc gatgccgatc accgcgacgg gccttgcgtg acgaccgggc ggatcagtca
     7621 tgggggtgga tgggcgggcc ggagccgcgt gagtgtgtcg cgcggccgcg gcgtcggagc
     7681 ccgttcaacg ggtggcgatg ctgacatgtg tgcgatcggg ctgtcaacgt aaggcaggtg
     7741 tgaccacaag gtgtgagtca ccgttcgata tgtgctgacg gacggacata cgtgaagtcc
     7801 cggcatgcct gtgcctacac gcagaggcat gtctgccctt aaggtgagga gcgaacatgt
     7861 tcgacgagcc gtccggcgtc gacatcgcgt cgtccatatc aagggagtga aggtgtgagc
     7921 agccaagcag cggccgagct ccgatcgcgg tacgtggaac aggtcgcatc ggaactggag
     7981 gagaaccgca ggcgccagga ggagctggcg aagaagatcg agctgcttca gcaggaggaa
     8041 gccctgctgt cggacatcct caatctcgcc gagaggtacg aaggcttcgc cgatgcctcg
     8101 cgtctgccgg agcaggcaca gggcgagccc gcggtggcga aggcgaagcg ccgaagtgcc
     8161 gccggagcga ccacgcggcg ttcgacgccg agcgggacgg cgtcggcagg gaccaggacg
     8221 aagagcgacg cgaaggggaa gccgggccgg cctctgctcg gggactcgct gatggacctg
     8281 ctgaccggtc atgacgaacc ccgttcggcg aaggaactgc gggacgaact tctggagaag
     8341 gacccgagcc gtaatccgac accgcaggtg gtacggaaca ccctcgagtc cctggtcgcc
     8401 aagggacgcg tccaacgcca caagcagcag cgggcggtca tgtacaccct cgtgaagcct
     8461 gccgacgacg ctgacgccgg ctgaggttcc gccgaacttt caaaaagcga gcgccttttc
     8521 gggctcacga ttcagggagg tgcagagctg tgcgttccat caccgctcca gcggtggcgg
     8581 cccccatcgt gccggggcgc ttacccttgc tcggccacct gccacagttg gccgtcaaac
     8641 gggtggagtt cctgcaatcg gtcaggacgc ggggcgacat cgtcaggata ttcctcggca
     8701 atcggccggt gttcatcctg aactcaccgg aggccgtcca cgacgttctt ctgacgcaga
     8761 gcaggaagtt cggcaaaggg ctgctgttcg acgtcgcacg gcctttcatc gggaacggca
     8821 tcatcacgtc cgagcgggat ttccaccttc ggcaacggcg cgcactccaa ccggcttttc
     8881 accggaacag catcgcggcg tgcgtcggca cgatgaccga catcgccgag gagcaggtgt
     8941 cggcctggcg tccgggcgag gtgatcgcca tggacgtggt gatgcgccgg atgatgacgg
     9001 tcatgctcgt ggcgacgctg ttcagcaccg aacgcccgga gggtgccgcg gccgtcgccg
     9061 aactggggga acaggtcgcc gagcatctga ccacggtgat gcgcggggtc ttcgtgggta
     9121 ctgtgctgcc cgcgccgatc gcctcttcac gtgtgctggg gcaccgcaag tacctggccg
     9181 cggccgcggc gctgcgcgaa ctcgcggaca ccgccgtccg gcaggcccgg cagactcagc
     9241 aggccggtca ggcccccacc gcccgcggtg acctgctgtc ggtcatgctc gcgggcaccc
     9301 cggggaatcc gcgggggatg accgacgtgg aggcccgcga cgagctgctg tccctgctca
     9361 tggccggtgc cgagaccaca tcgaccacct tgtcctgggc gctccacgaa ctcggccggc
     9421 gcccggagat cacccggcgg atgagggccg agtgcgacgc gctgcccgcc ggcgccctgc
     9481 ccggcgcggc cacgcttccc ttcaccgacc ggttcctccg ggaggtactc cggctccacc
     9541 agcccagctg gctgctcatg cggcgcgctc tggagccggt gcgggtctgc ggggtcgagc
     9601 tcccgcgagg agccgagctg gtctacagcg cggtgacgat gcaccgcgac ccggcgtact
     9661 acccggagcc actgcggttc gacccggacc ggtggctcgc ccgtaccgag aaggaccttc
     9721 caccgggcgc ctacgtcccg ttcgccctcg gcaaccggaa gtgcatcggc gaccacttcg
     9781 cgatgaccga gatgctcgtc gtcctgcgcg cgatcgtctc gcggtggcga cctcggccgg
     9841 tcgaggggca ccgggtccgg ccggtggtcc aagcgctgat ccggcccaat gcgctgccca
     9901 tgcgcgtctc accctggccg gccggctgag ccggccccgt ttcccggagg tgcgccacac
     9961 catgacatcg acggcattga cgacttcgac agcagagtac gtgtccgtgg atccggggcc
    10021 accggccccg gtccagaccc cggatcccgt tcccttcccg cgccggatca gtccggactt
    10081 ccgggccgcc cacgaccgtc acctcgcctg gccgaagtcc ttcggcttcc tgtcctcgga
    10141 agcggcggag gcccaccacc tcaggggcca gttcccgctg atcgcggcca tgttctatcc
    10201 gaacgcgacc ggaagcgaac tggacctcgg agtcgaccag cagagctggt acttcctgtt
    10261 cgacgacgcg ctcgacgaag agtggggccg gtcacccgag cgggtccgcc acctcgtcgg
    10321 actcgtcaag gagggcacca gcggcgaggc gtccccgctg cccctggccg gtgctttcgc
    10381 cgacatgcgc cgacgcagct gccaggacat gcccgaggac tggatccagc gatcggcggc
    10441 ccactggtcg tcctacctcg accaccacgt ccatgaggcg cgcagccgac agaccggcgc
    10501 gcccatgtcg ctgagcacat acctgcgggt ccggcgccac accatcggcg tggcaccggt
    10561 cgtcgacctt gccgagcgtc tgtcctcgtg cgtcctgccc gaccaccttt acgcgctgcc
    10621 gcacctgtcg gtcatgcgtg agatgacgaa gaccttcatc atctgcgaca acgacatcgt
    10681 ctccctggaa aaggacacgg cactggggga gcgcaacaac ctggtgctct gcctggaacg
    10741 ggaccacggc ctctcccggg ccgaagcgat cgaccaggcc ctctgccgcc gggccgaagc
    10801 cctggaactg ttcaccggcg cccaccgggc cctgctcggc gccacggcga cgagccacct
    10861 cgacccggcc gaacgcgacc tgctccagcg ctactgcacg gaggcgcttc ggaccaccat
    10921 ccgcggtgcc cacgactggc accacgcctc cacccggtac cacgggcagt cggcgcctcc
    10981 cgttccactc acacgaccgc gttcccagga ccgaagcagc tgaggagcac cagcatgccc
    11041 gaccaccgcc cggcgtcctt cgtagcctct gaacgagacg ggacctgccc gttcgacccg
    11101 tcgccggacc tgcgccggat gcgcgaggag gacggccttc cgcgactgcg cgtcctccat
    11161 ccggtgcgcg gcgagatcga ggccgtcgtc atcaccggat acggcgacgt ccgggccgcc
    11221 ttcgcggacg agcgcctggt gacgggcaac ggcatcgacc cgacgctgcc gcgcaccctg
    11281 ttcaaccacc cgggcttcct gcccgcctac agcggcccgg agcacgcccg cctccgccgc
    11341 atgctcaccg gcagtttcac cgtccgtcag gtcgagcgac tgcgtcccgc gatcgagacg
    11401 atcgtcgccg accacctcga cgccatggcg gagcagggac cggtcgtcga cctggtcgag
    11461 gcgttcgcgc tgcccatccc gtcgctggcg atctgcgaac tgctcgacgt tccctacggg
    11521 acccggtcca tgttccagcg ctgctcccag gtgatcatgg acgggaccgt cgacgccgac
    11581 cggctggtcg ccgcctcggc cgagttgaac gccgccatgg cagacatcgt cgcccgcaac
    11641 cgggcaaccc ccggggacgg agtgctgggc acggtggtgc ggcagcacgg cgcggagctc
    11701 accgacgaag aactcatcgg gttcggcacc accctcctgg tcgggggaca cgagaccacg
    11761 gcgaccatgc tcgcgctgag cgtgctggcc ctgctccgcg gcccggacca gctcgccgcc
    11821 ctccgcgacg accccgcggt caccggtacg gccgtcgagg aactcctgcg ccacctcgcc
    11881 atccccgcac cgctcctgcg cacggccgtg accgacgtcg agatcaacgg ccaccggatc
    11941 gccgaaggcg agcacgtact gctctctccc ctgaccgcga accgtgaccc cgggctcgtc
    12001 cccgagcgcc ccgacgacct cgacctgcgt cgccgtccgg tcgcccagct gtccttcggc
    12061 ttcggcgccc accagtgcct cggccagcaa ctggcccgcc tggaaatgaa gatcgccctg
    12121 ccggccctgc tccgccgctt ccccaccctc cgactcgccg tccccgaagc cgccctccgt
    12181 ttccgtgagg gctcgacggt ctacggggtc gaggtgctcc cggtcacctg gtgaggcgtg
    12241 gcgtcgtcag gccgtgccga gccaggcctc ggccagggcg ggcagcgtcc cggcgccgag
    12301 gcgccagtgg ggcgccgtcg aggtcgcggc gcggcgccac gcctcggtca ccacgtcgcg
    12361 catccatgtc cggacgcgga cttgttgctc cgtgccccga tgcgtcccgt atgctcccgg
    12421 gcatgagcac tgcgcaaccc gcccgtaagc gcgacgccgc cgccacgcgc gaggcgatcc
    12481 tcgccgccgc ggtcgtggag ttcaccgagc acgggtacgc gggtgccgga gtgcgtcgga
    12541 tcgccgagcg ggcgggggtg acagcgatga tggtcaaccg ttacttcggc tccaagcagg
    12601 gcctgttcac gcaggccgtc gcgcgttcct tcgcgccgcc gaccatcgtc ggcgacgaac
    12661 gcgccgactt ggcgggggcc atcgcccata cgctcaccga gcgcacggcg tccgacgccg
    12721 agcggctcga cccgttcctc ctgttgctgc gctcggcacc ggatcccgag gcggcggaca
    12781 tcgtccggcg gggcgtggaa gccaatgtgg gtgctcgcct ggctgggctg ctcgacgggc
    12841 cggacgccga cgtgcgtgcg cagctcgccc tcgcgctggt cgccgggacg tggctgctgc
    12901 gcggcgtcgt cggcaccacc gcgctcgcca cggccgacga cgcccgcctc atcgccctgc
    12961 tcaccgacat gctcgaaccg gtcgtccacg aggtgggtgg cacgtccgcg gcgacgggaa
    13021 ccggtcctga cggcacccaa ggctagcgac ccgccgtcgg tgctcagaag gcggagcgga
    13081 tgagcccgcc gtcgacgcgg atggtggctc cgctgatgta ctgcgcgtgg tcgccgcaga
    13141 ggtaggcgac ggccgcggcg acctcctcgg gcttgccgaa acgttcctgg tcgttgggga
    13201 tgagggcctg gacggcgttg ggctcgacct cgtcccaggt ccggccccag ccgcgggcgg
    13261 gcccgatccc cgtgaagaag tccttggtgg cctcgacgag gatcgctccg ggggagacga
    13321 cgttggacgt gacgccggtg cccttgagtt cgcgggcaag ggagacggcg aggttgtgcc
    13381 gggcggccag ggtggcgttg tactgggggt gggcgtccat cggctgggag gcgagcccgc
    13441 cgccgatggt gacgacacgg ccccagccgc gttcgcgcat ggcggggacc aggtgccgga
    13501 tcatccggac gcctgagacg acgttggcgt cgtaggtgtc gcgccattcg tcgggggtgg
    13561 cctcggccca ggtcaagtgc cggtaggaac cggcgttgtt gacgaggatg tcgaccggac
    13621 cgcccgcggt ggcggcgcgg gcgacgccgg ctgcggcgtc gtcgtcggcg aggtcgccga
    13681 cgaccacgtc ggccgtcccg ccggcctccc ggatctcccg ggcgacccgc tccgtgcggc
    13741 gcgcgtcccg gccgtgcacc acgaccccgg cgccctcggc cgccaggaat ctcgcggtgg
    13801 cctcgcccag ccccgcgctc gagccggtga cgagtgcgcg cttgccgatg agattgaggt
    13861 tcatcctgtg ttccctctca gggcccgctt cgtggcccgc gctgtgtggt ggtgcgaggc
    13921 atccgacacg cgcaagtcta cactcgtaga cttatgcctg tcgggcgcaa gggcgtcgca
    13981 gcccgccggg cgcaccctca gccgccacat cgcggacccg ccggacgaga tggcacctcg
    14041 ggcgccccgc cctcacaccc cggccaagcg cctgcctacg ccggaacgca gcccgcacca
    14101 gcgcaaaggc cctagagaaa cgggcctgtc ccctctgtaa cagcaccgtc gagacgtcac
    14161 gcagcgtccg gcagatctac tgctctcccg cctgtcgcag aaaggccgac cgtctccgcg
    14221 gccaggcccg cgaccagggc cgagcccgcc ggctcggtga gagccgccca gccggacacg
    14281 gaccgagcct ccatcacccg cctggttcca caccccaccc cgcagcacct cggcaactct
    14341 ccaaggggta cgacccgttg gagcccgcag ctactcgcaa ctgcccacac tgcgaccagc
    14401 cgatcacgat cgtcgccctg ctggccaccc ccgaagccat ctggaggctc ccgggcaggg
    14461 tcgtcgcccg cctcgaccgc tttaacgggc aggagatcgc ggaacgggaa ctggccgtgg
    14521 cccgatggct cgccgacaac ggcgttcaca ccgcccgtcc ggcggtcgtc gatcgacctg
    14581 ccctcgtcga tgggcagccg gtgacgttct gggatgagct cacaccccac cggccgggaa
    14641 ccgccgccga cgttgcccgg ttgctgaagc agatgcacca gctacccccg ccggcctccc
    14701 tccgcctgcc gccgctcgaa cccctcacca agcccacacg ccgcatcgcc aacgctggca
    14761 ttctcaccac cgatgaccgc cgctggctcc aggaccacgc tcgccggctc gccgcggatt
    14821 tcgccggcct cccggccggc ctgccgctgt gcgctctgca cggcgacgcc tgggacggaa
    14881 acgacgccgt cgacgccgac ggcaccgcct gcctcctcga cctggagaac acctgctgtg
    14941 gaccaccgga atgggacctc gtctccacct cggtgaagca ccgcacgacc gccaccgtca
    15001 cggcagccgc gtatgaggac ttctgctcgg cctacagcat ggacgtcacc tagtggcccg
    15061 ggtactcagt cctggcgggc atccgggaac tgcgcatcgt caccttcgcc ctccagatcg
    15121 ccgaccaaca ccctcacgcc cgcgcggaag cacagcaccg tgtcgactgc ctgcgcggcc
    15181 gcaagggccc acgcccgtgg acatggacgg ccgtaccgtg accggggcgg gtttccctcc
    15241 ggtccgagcg gtccagtgtg ccgggctgag cgcagagcgc tgcgcgcccg ggcggcgcct
    15301 gccatgccgt agggcgggaa gcgccggtgg cgggacgggg gctcaccgtc atcggccctg
    15361 gcctgaccag cggcatcggc ggtggtctcc cgggctgcag cgccgagaag gccaccggcg
    15421 tcagcccctg cgaggaaatc atgggcatcg cctccaaggc ctacaacgag atccagcgct
    15481 acgcactcac ccacgagcag gacgaccagc cccggacgca ccaggaactg ggtgacaacc
    15541 gctgactccc ggtgagcggc cgggggatcc gcgctccgcg agggcgcgat gtgccgtcaa
    15601 cgccgagcaa ctcgcggacc gtcccgtcag gctgccgggc gtcgcccggg caacggcttc
    15661 gccccgggct cggcgtgtgg ccgggcccgg ggcgaaggag gggtgcctta ccgcgccggt
    15721 acggtcagtg cgaggcggcg cgcctgcggc tccgtaggcg tgggagaggg agtagcccag
    15781 ctcccccgcc ctcgtggatc gacctgcggg tctcgggggc gacgtggctg ggtacgccgc
    15841 cgggaaggag aactgccgga agagccgctc catgcccgcc gcgttccggt tgacgtcggg
    15901 gtaggtctcg gcgtacatcc cttccagcca cgggttggcc atcagataga tctgcccgac
    15961 ggtcaggtag ttcgcggccc gccagtgagc gtccagggcc cgcagctcgt cgtcggtgag
    16021 agtggtggcc ggtgccgacg tcgtgacgtc ccgcatgact gcctccgaag ggttggacgg
    16081 ggccctgtca ggagcctttc cccagcctgg gtttcgcgcc gggctgccgc cagggccgat
    16141 cggagggcac ccgggcccat tcggcccagg cggggccggc cgggtaggtc cgcgccgtag
    16201 tgtcgggagg ggcgtacggg aggagaggac agtgactgac gacgatcgac cgcaccggtt
    16261 gtcgcgcccg ttgtacgagc gggagctgct gcggcttcag gtggagctgg tcaagctcca
    16321 ggagtgggtg cgggccgagc gccggcggct cgttgtggtc ttcgaggggc gcgacgcggc
    16381 gggaaaaggt ggcgcgatcc agcgggtcgt ccagcgcctg aacccgcgtg tcgtccggat
    16441 cgccgcgctg cctgtgccga ccgagcggga acgcacgcag tggtacttcc agcgttacgt
    16501 gggacagctg cccgccgccg gggagatcgt tctgttcgat cgcagctggt acaaccgcgc
    16561 gggcgtcgag cacgtcatgg gcttctgtac cgacgaggag tacgcgcgtt tcctccgcca
    16621 gtgccccgta ttcgaacggc ttcttgtcga ggacgggatc ctgctgcgca agtactggtt
    16681 ctcggtgagt gacacggtgc aggagcagcg gttccgtgac cggctggcgg atccgacacg
    16741 gcgctggaag ctgtcggcga tggacctgga gtcgatcacc cgctgggagg cgtactcgcg
    16801 ggcgaaggac gagatgttcg cgcacaccga cattcccgag gcgccttggt acgtcgtcga
    16861 gagcgacgac aagcgctcgg cccgcatcaa catgatcgcc cacctgctgt cgacggtgcc
    16921 gtaccgcgac atcccgatgc ctgccatcga tctgccgccc cgcccaccct ccaccggata
    16981 ccagcggcct cctcgggatc gacagacacg ggtgcccgat cgcgcagcgg agcttgcacg
    17041 ataggactgg aacgatgccg aggtgtggtg gcgaagctgt gcgggacgac gtaccacgac
    17101 ggtgcgccgc ttccgatcgc cggtggtcga gcggctggac gagcggagtg cggtcagcag
    17161 tcagcggtca gcggacgatg cggggcggca gctgcgccag gagcagggtc acatcgtcgt
    17221 cgcccgcgct gcgcggcagc agggccgaga ggaccgagtc cgccactgcc tccaggtctt
    17281 gtgtttccag gttctgctgc ttgtccagcg ccgtgcccag tgcggtggtg agggccgtga
    17341 tttgcttctc gatgtcggtg ccgggcgtct ccaccaggcc gtcggtgtac agcacgagag
    17401 tggcgcccgg tggcgcggtg cgggtcacct gctcgtgcgg gaagccgctc acgcccaacg
    17461 gcacgttcac cggtgcgggc aacggcagga cgtcgcgctc gggagcggcc aggagcaccg
    17521 gtaggtgccc tgccgaacag agggtgatct ctccgctgcc ggggtcgacc accaggtagc
    17581 agcaggtgac cagttggccg gggaggtcgg tgacgatggc gtcgaggacc tccatcagcc
    17641 tgtggggcgg catgccggtg cgggccaagg cgttggcggc ggagcgcagc cggcccatga
    17701 cggcggctgc ttccagacct cggcccatca catcgccgat caggacaccg accttgccgt
    17761 ccgccagcgg gacgaggtcg aaccagtcgc cgccgacgcc ggcgccttgg gtggcgggca
    17821 gatagcggct ggcggtgagg aggccgggca cgtcgggtgg ggtgcccatg aggctgtgct
    17881 gcaacgtcag cgcgacgtgc cgctgctgct cgtagagcct ggtcagctcg gcttccgccg
    17941 ccttgcgttc ggtgacgtcg cgcacggccg ccgagaacag cactccctca cccgttcgca
    18001 gcgggctgag gctgatctcg acagggaact cgtgcccgtt cttgcggagc ccgtagaggt
    18061 ccagcccggc gcccatggga cggaactgct gattgtgcgc gtagtccttg cggtgtgccg
    18121 cgtgccggtc gcggaaccgg ccgggtacga ggacttccac cggacgaccc aacagctcgt
    18181 gccggttgta gccgaacaga acctccgtct gggagttgac cagacggatg gcgcccgtgt
    18241 cgtccacgat gaccatggcg tcgggggctg attcgagcag cccccggaac tgttcgttcg
    18301 ccgcctcgca accgtccgcg cggatgacct cggccccaca ggggcaggcc gcccggcctt
    18361 tggggtcatg cccgtgagaa acggtgcgtc tggtcatccg cctgcctttc ctgggcgcag
    18421 ggggtgcttg cgtcgcgcgc acaaaggtcc caccgctgcg agccgatcgt ggcacgcagg
    18481 cccggcctgt gacgtcccat ggttgtagtt gatcgcttct caccgggaaa gggcgaagaa
    18541 ctgtccgttc atggccggac gcctgaagcg cgattccttc ggccatggcc ggtacggcgt
    18601 atcccagttg tgatggggcc tgacaggcga agcagaagat ttcgatggct cggtgaaggg
    18661 ctgcgcccct ggggccaggg gctgttctgg gtctgctcag tcgtctttca cggtgaagcc
    18721 gacgtgttgt gccaggaggg gtgccaggtc gaatagctgg gttgtgctga ttgtcgcgcc
    18781 actcagggat ccggtcccgg aagcgatgcg cagggtggtg gcctcgcgca ggtcgacggc
    18841 ggtcagcgtg gccttgtcga agcgggcccc gtcgagggcg gagccgggga agcacacgcc
    18901 attgagtgtt gctccgctga agtccacgtc acgcaggaga cagtcgacga acgtcacgtc
    18961 cttgagtgtg gctgcgcgca ggttggctga gtcgaatttg cactgatgga agacggtgcg
    19021 gcgcatctcg gcgccgtgga cctcggcgcc ggcgaagatg ctggcggtgc actcgctgtc
    19081 cagccaggtg gtctcggcga ggttggtgcc gaccatccgg acggtgtgca gccacacgtc
    19141 gtcgaagcgc gagcggcgga aacggccgcg gttgaaggtg accgaggaga aggccgactc
    19201 actgaagagg gaactgctgc cctccgcgtc gtcgaaggtt cggccttcga agtggagcca
    19261 ttcgtatgtg cctgatcgct cgatctcccc ggtgaagggg ttgaggcggt gcgcaaacgg
    19321 cagtgtggcc aggtctcgcg gggcgcgggt tcgcataggg cttcctccag gggacggggg
    19381 tgggcagccc tcacctgcgg gccttggcag gaccacggtg agggggaggg cctcatgctg
    19441 acgccaggcg cgtcgtttta tccaatcgcg ctcgggtccg acgaccggct ccggaggcgg
    19501 aggagatcta gcgccactcc agaaactata taaaaacata gaaaagggac acatggtctt
    19561 gctgtggttg tgacattcct ccggtacccg agttgcaggt atcccgtagt gatctctctt
    19621 cagatcacca agtacgccct gcggaaggcg aattggctcg cgtgcggccc ctgtccggcg
    19681 accggttctg cctggagacg cagttccccg aaattgattc tgcgctttgt tccctgagcg
    19741 gcttaactgc cggccttgct cacgagccgt cctggagagg agaggcgatc cccgcttcgc
    19801 cggtggtcct cactgctgca ggggcttgtc ggcacgtctc ccgggtgcga gtagttgggt
    19861 acaggaaatc ccggcgatat tgatcttggt cggccagcac accgttccgt ggcctcgccg
    19921 aggtttacgg aaagatcgtc gagtggtacc ggcgctggct acggtccgcc tcgtgccggt
    19981 ggagtttctg actgatgagc aggccgaggc gtacgtgacg ttcaccgagg cacccacgcg
    20041 cccggagctg gagcggttct tcttcctcga cgatgacgac cgcgatctga tcgcgctgcg
    20101 tcgtgcggac gcgcaccggc tgggtatggc ggtgcagatc tgtacggtcc gctacgtcgg
    20161 ccggtttctg ggggaggacc cgctcgccgt gccgtgggag accgtggagt acctggccgg
    20221 acagctcggc atcgcggacg cctcgtgcgt gaagcggtac gccgagcggc gctcgacggt
    20281 gtacgagcac gccgatgaga tccagaggcg gttcaaatac cgcgacttca ccgaccggaa
    20341 gtgggggcgg gaattacgca gcttcctgta cgggcgggcg tggacgcacg ctgaggggcc
    20401 ggtggcactg ttcggccacg cggtgacgtg gctgtggaag aaccgggtgc tgctgccggg
    20461 tgtctcggtg ctggccggcg ggtgtcggag gcgcgtacgg cggccgagcg gcgcctgtac
    20521 aaggcggtgg cccgcgcggc ggaccgagcg gatgcggcgc tcgcgccggc gttggccgag
    20581 ctgctggtgg tgccggaggg caggcgggtc tcggagctgg agcggctgcg cgccccgccg
    20641 gtgaagtcga cgggcacggc gatggtgcgg gccatggagc gggtggagga gatctccgcg
    20701 tgcccgacgg cgagacgccg gccgccgggt acgggccgct ggaggccatc gcctgcacaa
    20761 ggtgaacctc aagcggatcg ccacgcactg gccggacatg ctccgcgtcg ccgggtcgct
    20821 catcaccaac caggtccgcg cctacgacct gctgcggatg ttcggccgcg agggccaccg
    20881 accccgctcg gcgcagcgtt cgtcgagtat ggccgggtcg acaagaccat gcacctggtc
    20941 gcgctggtcg cacccggtcg acgacaccta ccgccggctg atgaaccggc agctgaccgt
    21001 gcaggagtcc cgccaccgcc tgg
//
