LOCUS       NZ_CP034587            20597 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6000462
            Orig. end                         :: 6021059
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20597
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20597
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20597
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10597](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10597
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(1453..1467)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    2644..2655
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     misc_feature    3291..3306
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.94"
                     /tool="antismash"
     tRNA            3430..3503
                     /anticodon=(pos:6003926..6003928,aa:Pro,seq:ggg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EKH77_RS26760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EKH77_26760"
                     /product="tRNA-Pro"
     gene            3430..3503
                     /locus_tag="EKH77_RS26760"
                     /old_locus_tag="EKH77_26760"
     misc_feature    complement(3508..3523)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            complement(3565..4806)
                     /locus_tag="EKH77_RS26765"
                     /old_locus_tag="EKH77_26765"
     CDS             complement(3565..4806)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031194.1"
                     /locus_tag="EKH77_RS26765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26765"
                     /product="site-specific integrase"
                     /protein_id="WP_126916838.1"
                     /transl_table=11
                     /translation="MQKQIPPIGVKLSVDVEYREGFPNPHRARVRWFDPESGQRLSRSR
                     MLPTDDEAQSWVDRMERIAQRGVSPAVATMPLAEYGELEWDLAMRGLEPKTMDPYGAGW
                     RLRVVPAIGHLEVPVITNGVVDRTVYGWIADGHGRSTVKNSIAPLNRVMEQAVRDGIID
                     VNPAKITGWQRTYQQVEDELDDPRSLALRDWDALDDLANALVERSHDQYLGWGDVVRFS
                     ACTAARIGEVSGVRAQDIDRRTWTWECCRQTTPGPGGLIDKGTKGKRRRAVPLIPEIRP
                     MVSARLDAVGNDPMARLFTGPRGGRITTAILRDATHWDEVVVRLGYEHLRRHDLRHTGL
                     TWMADAGIPVHVLRVIAGHGSITTTQRYLHPDRRSIHLAGAALSRYLTDGRREAAGPKL
                     VPEPAPVRHLRLVR"
     gene            complement(4806..5069)
                     /locus_tag="EKH77_RS26770"
                     /old_locus_tag="EKH77_26770"
     CDS             complement(4806..5069)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345390.1"
                     /locus_tag="EKH77_RS26770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26770"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_126916839.1"
                     /transl_table=11
                     /translation="MPDRATPHISPASSKEISVDSLTASWYTTEEVARLLKRDPSTLRR
                     WRTARPPQGPPFVQLSQRAVMYSALDLQQWLVSRRIDPAQAA"
     misc_feature    complement(5202..5216)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(5395..5411)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.15"
                     /tool="antismash"
     gene            complement(5409..5792)
                     /locus_tag="EKH77_RS34000"
     CDS             complement(5409..5792)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS34000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="transposase"
                     /protein_id="WP_240667548.1"
                     /transl_table=11
                     /translation="MNRLLFPGARKAIQIKRRRTCRKTGKTTVKTIYAVTSLTAEQASP
                     ARLARLVRDHWGIESLHHLRDTTFAEDASPPRTGNAPRAMATWRNLAIGILKRSGVTNI
                     AAALRRNARDPQQPLALLGLGLG"
     misc_feature    5752..5765
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     gene            complement(<5968..6630)
                     /locus_tag="EKH77_RS34005"
                     /pseudo=""
     CDS             complement(<5968..6630)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033564.0"
                     /locus_tag="EKH77_RS34005"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRPPSPADAAVHPDAETTPRTSQQVVHASTPVCPHHINDRRSVK
                     QHVDSLQALKWRRKSYPTFHVSLTACAVPAGATSLAAVGEWIADAPFHVLEQLDVRLDP
                     LLPRRLAPSWSAVRRLRARLNADALDRAVGRWLADRRPQPSGGADLRGVSVDGKSLRGA
                     ARTKGRKIHLLAAMEHTSGLSLAQLDVGEKTNEITCLRPLLDTVADLAGTVVTSDALH"
     gene            6525..8216
                     /locus_tag="EKH77_RS26780"
                     /old_locus_tag="EKH77_26780"
     CDS             6525..8216
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734794.1"
                     /locus_tag="EKH77_RS26780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26780"
                     /product="ISAzo13 family transposase"
                     /protein_id="WP_276319241.1"
                     /transl_table=11
                     /translation="MGIPESTREQLAVKFAVLFPHLDERQRRLVMGAEARILGHGGIRA
                     VARAARASETTVRKGVNELETGEARLGRVRRPGGGRKKAAELDPGLRPALLALVEPDMR
                     GDPMSPLRWTVKSTRTLAAELTRQGHRASADTVGDLLREEGFSLQANAKTIEGTQHPDR
                     DAQFRYLNEQARDHRDTGDPVISVDTKKKELVGQYKNAGRSWQPAGEPVMVKTHDFPGQ
                     ADKAIPYGIYDMTANTGWVNVGTDHDTAAFAVASIRRWWQARGRHDYPGARRLMITADA
                     GGSNGYRTRGWKTGLAALAAETGLDITVCHLPPGTSKWNKIEHRLFSHITMNWRGRPLT
                     SHEVVLQSIAATTTRTGLTVHAELDTGQYPTGIHISDEAIAALPITRHRFHGDWNYTLR
                     PQLPLEATPVSSTAADQASAGTNPGLTLHSLQDPELTGMPRQQLSELIDALMPQLELQR
                     ERTLRIRRGHERLVAPGTGAKAKLTPADRILATVLHQRKLATMDLLGQLFGVTAMTISR
                     ANQEVRPLLETHGHHINASTARFRTPADITTFLAPHPTQSEIKSAC"
     gene            complement(8552..9043)
                     /locus_tag="EKH77_RS26785"
                     /old_locus_tag="EKH77_26785"
     CDS             complement(8552..9043)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074196.1"
                     /locus_tag="EKH77_RS26785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26785"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_126916840.1"
                     /transl_table=11
                     /translation="MNNVYFDIIMPRRDAERVVFKLYDDVVPKTARNFRELATGQHGFG
                     YAGSSFHRIIPEFMLQGGDFTKGNGTGGKSIYGETFDDENLTLKHNKVGLLSMANRGKN
                     TNGSQFYITTVSASWLDGKHVVFGEVVEGYDTVKTIESFGSSSGTPREKVTIAQSGIVK
                     "
     misc_feature    9085..9100
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.47"
                     /tool="antismash"
     gene            complement(9313..>9724)
                     /locus_tag="EKH77_RS26790"
                     /old_locus_tag="EKH77_26790"
                     /pseudo=""
     CDS             complement(9313..>9724)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="EKH77_RS26790"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EKH77_26790"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="DATGIPLAVTLTGGNRNDVTQLIPLLEAVPSVRGKRGRPPCRPDV
                     VFGDRGYDHDKYRRLVRVLGVKPLIARRGTGHGSGLGAQRWVVERAFRPLALVPPPADP
                     LGDPRRHPQSFPHPGVCTHLLAPPGSSSTPPLI"
     misc_feature    9928..9943
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.04"
                     /tool="antismash"
     gene            10001..10597
                     /locus_tag="EKH77_RS26795"
                     /old_locus_tag="EKH77_26795"
     CDS             10001..10597
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="EKH77_RS26795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26795"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_276319264.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.4e-19, bitscore:
                     66.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.6e-16,
                     bitscore: 58.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTAQTCGLSPQWALDQLEGMHIDIGFTGFTTEADYQAYVDAVTW
                     PGAMITSGLIPHQVPDHDFAQTCRVLSDGIQRTDNLFDMADDLREGRMTLPTADLDRHG
                     VTRRELALGVDTPGLRALLTAHVRTAREALERASRMFDEVPPEFAPSVRCLIGLYHHRL
                     NQVVDRGVTIARTPVRDDPLTCLRLLASARTPVFA"
     gene            10607..11296
                     /locus_tag="EKH77_RS26800"
                     /old_locus_tag="EKH77_26800"
     CDS             10607..11296
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473850.1"
                     /locus_tag="EKH77_RS26800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26800"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_240667549.1"
                     /transl_table=11
                     /translation="MTTPSRSTAATAHPDLPGPGSVTWERMGRWATLSVGLRALVLQTA
                     HPVVGAGVAEHSDFRDDFFPRFTRTLASTLRFVYGTPAEAAAEGRRLRALHARIRGTDH
                     HGRPYRALDPQAYAWVHATLFEAVVALGPALPGVPPPPLVPALLWRVAWPPIARYAVRV
                     TVPTLPPAYLDRLGLASTSTDTRRTSRFFARTARIDRLLTSRYRYLPAAAKARRQADTA
                     NALMARP"
     misc_feature    11668..11684
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    11749..11769
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 24.98"
                     /tool="antismash"
     gene            11795..12121
                     /locus_tag="EKH77_RS26805"
                     /old_locus_tag="EKH77_26805"
     CDS             11795..12121
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573954.1"
                     /locus_tag="EKH77_RS26805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26805"
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_126916842.1"
                     /transl_table=11
                     /translation="MGVTREIIEPGDGVNFPKKGDTVTMHYTGVLTNGQKFDSSHDRNE
                     PFKTPIGIGKVIKGWDEGVPQMSLGERARLTITPDYAYGSGAVGKIIPPNATLIFDVEL
                     LKIN"
     gene            12260..13547
                     /locus_tag="EKH77_RS26810"
                     /old_locus_tag="EKH77_26810"
                     /pseudo=""
     CDS             12260..13547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981789.1"
                     /locus_tag="EKH77_RS26810"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26810"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLQGDRQEAFVRLSHFRTELYACLAARGDALFELCDALLRMDGPV
                     RTLVDLALAPEHRRGHGALYGGLNRGDRRRPTASRAGRRCRCRKRRMFGSFWPQMSLRG
                     CGRTPTPALTGPSATRSAAGKASTRWSRAGPTRSSPHWRPAARPGQRYWMRSAWSPAPM
                     SPR"
     gene            13544..13669
                     /locus_tag="EKH77_RS34600"
     CDS             13544..13669
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS34600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_346429076.1"
                     /transl_table=11
                     /translation="MTAWRNLAIGALRLNGVTNIATALRRNARDPRRPLALLGLA"
     misc_feature    complement(13670..13679)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     gene            13839..14720
                     /locus_tag="EKH77_RS26815"
                     /old_locus_tag="EKH77_26815"
     CDS             13839..14720
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000096.1"
                     /locus_tag="EKH77_RS26815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26815"
                     /product="DUF5655 domain-containing protein"
                     /protein_id="WP_126916843.1"
                     /transl_table=11
                     /translation="MSGLKLFNVGAGGAEEIPARPVARERCLQELVEQHMETFLGVRFL
                     ASEYSTGPRHGGRIDSLGLDENGAPVIIEYKRGQDAGVINQGLFYLSWLIDHKAEFQHL
                     VRERLGAAAAAQVLWNDPRLICIAEDFTRYDAHAIGEIQRTIDLVRYRYFGGDLLALEP
                     VASVTGRERQPRPRRVGARPGRHFGGVAEELRSAVGEVLVSLGDDVTHVDRKQYRAYRR
                     LRNFACVSRMHKQHVLIYLNADPGKVDLIPGFTRDVTNVGHHGTGPLEVRLRTEKDLER
                     AVPLFRLGYAGA"
     gene            complement(14765..16006)
                     /locus_tag="EKH77_RS34015"
     CDS             complement(14765..16006)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /locus_tag="EKH77_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_240667550.1"
                     /sec_met_domain="HAD_2 (E-value: 2.8e-25, bitscore: 88.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTPRPAIQSRHTDPARRGGQRSLLLDLDGVLLDTRPVMQKAWG
                     AVQQRHRIEVPFEQYEQHLGRPFNDIMRRLTVTDAEAVHQTYSEASKAVAHLARPFDGV
                     EEVLHTLVARGWLLGVVTSKPLDRAAPLLAQLGCPFGSVRAAGGPGRSKPAPDPLLLAL
                     VDLCADPAQATFVGDMAVDHEAARRAGISRRWRAHSGATPRGGSPPPLRELPPNDQRHA
                     DEQAFLSAVTTRPNELGGIRSYLSPGDFADPLHQQLYRCLTALHHRGEPIDPITVLWEA
                     QHRGVLASTTPETVLTTCARSGNDPDYWATRILDHALLSTTAASAEHIKLAVDDPTMTP
                     QQLITVCRRALRDLTAVRLRRHHAHQRPPAPPLRSSRPPTQRSVTRPPPRIAPVNPFGP
                     SYSAPRAPTSSSSR"
     gene            complement(16097..16291)
                     /locus_tag="EKH77_RS26825"
                     /old_locus_tag="EKH77_26825"
     CDS             complement(16097..16291)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS26825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_26825"
                     /product="hypothetical protein"
                     /protein_id="WP_126916844.1"
                     /transl_table=11
                     /translation="MNDRARPRRRLAWYDPVGTVCKWTYGVGVLATLGLLGQLVRLEHH
                     HNAVPNPPSASVPDLPAEE"
     gene            complement(16288..16605)
                     /locus_tag="EKH77_RS26830"
                     /old_locus_tag="EKH77_26830"
     CDS             complement(16288..16605)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039764.3"
                     /locus_tag="EKH77_RS26830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26830"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_126916845.1"
                     /transl_table=11
                     /translation="MSTVRVTLGRLPLAATVEHLLLRLRGHIQLLLPEIEAKGWARYGQ
                     DDQIRLMTASVRDRLNNEPKTGPAVVRCVYAQELAHICRGLLALALAEPGFEQPFPAAA
                     S"
     gene            complement(16704..17498)
                     /locus_tag="EKH77_RS26835"
                     /old_locus_tag="EKH77_26835"
     CDS             complement(16704..17498)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (12-233). E-value: 5.7e-24. Score:
                     77.2. Matches aSDomain:
                     nrpspksdomains_EKH77_RS26835_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.4"
                     /locus_tag="EKH77_RS26835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26835"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_126916846.1"
                     /sec_met_domain="TauD (E-value: 6.2e-22, bitscore: 77.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREAKPFTAHYVDVQSSRAEEVVRERLRDIGMITLSGFTSRTVVR
                     EFASRIMDITPHRDSDPDGLTTLRDTRRHMRLAGYGGFGNGELAPHTERSGVPEPPRLM
                     LLVCGTPAHHGGDCLLTDGRAVYADIAARHRDAIVALSKERTAFFGGGDGHATQVFTEH
                     PDGRVSVRLRLDGLARFNPTVQSYLPDLRSTLTTYQIRLPLDAGQGYLIDNQRWLHARE
                     SFTGNRLCWRVLGEPRFPLLRGFAPASRSAARPTASGRVVVS"
     aSDomain        complement(16800..17462)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS26835_TauD.1"
                     /evalue="5.70E-24"
                     /label="EKH77_RS26835_TauD.1"
                     /locus_tag="EKH77_RS26835"
                     /protein_end="233"
                     /protein_start="12"
                     /score="77.2"
                     /tool="antismash"
                     /translation="DVQSSRAEEVVRERLRDIGMITLSGFTSRTVVREFASRIMDITPH
                     RDSDPDGLTTLRDTRRHMRLAGYGGFGNGELAPHTERSGVPEPPRLMLLVCGTPAHHGG
                     DCLLTDGRAVYADIAARHRDAIVALSKERTAFFGGGDGHATQVFTEHPDGRVSVRLRLD
                     GLARFNPTVQSYLPDLRSTLTTYQIRLPLDAGQGYLIDNQRWLHARESFTGNRLCWRV"
     misc_feature    complement(17418..17420)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17667..18086
                     /locus_tag="EKH77_RS26840"
                     /old_locus_tag="EKH77_26840"
     CDS             17667..18086
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010272230.1"
                     /locus_tag="EKH77_RS26840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_26840"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_126916847.1"
                     /transl_table=11
                     /translation="MTYKPPTWPVSVKAVALDIRQRVLLLKNERAEWELPGGRLEHDDD
                     SPETTVERELLEETGWEVKTGPLIDGGVWIYEPIPGRRVLIVTYGCTVLTPDREPVVSH
                     EHKSIGLFTADEVPELNMPDGYKRAIATWYGQRQR"
     gene            18111..19271
                     /locus_tag="EKH77_RS33410"
     CDS             18111..19271
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS33410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_206279932.1"
                     /transl_table=11
                     /translation="MPSAPRPAARHVVWHWATPQAEAVLASRELGTILRFHRAVHRLNQ
                     TELGEALGYDKTYVSALELGKRSLDDVGSRRRVAERLGLPPHVLGVTDVADTDHRAMVQ
                     FGESTVRLAEIARQSGHASEAVAELWPLVARLEARVEDGHSERDVVRLLARARVGLGVA
                     LGNVLPEERLATAARWTARSLEAARHLGDDPALLSGILRMHGNELRKARLTGAAVERLR
                     HAAAIAPTSDDRAAVLPLLARAAGAIGDRNLFDTVMRETDSLLERAAHTSLFNPYSLHE
                     IRLRGLLATGRAPAAIRLVEERPALTTRVAPQWRVIELVTVAQVRLIGGDRAGAAEALD
                     VALGEAVVQRLPHQVQRMMRAAGQRLPDIRVAAGEALDRMRQEMAA"
     gene            complement(19292..19474)
                     /locus_tag="EKH77_RS26850"
                     /old_locus_tag="EKH77_26850"
     CDS             complement(19292..19474)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS26850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_26850"
                     /product="hypothetical protein"
                     /protein_id="WP_126916848.1"
                     /transl_table=11
                     /translation="MSGPTPRPEQKLESPAESPVGAHYRKAHGDATTWPAHDFEVYYDL
                     ARAVPFPDLGPGQIR"
     misc_feature    complement(19615..19630)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.39"
                     /tool="antismash"
     misc_feature    20095..20108
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.66"
                     /tool="antismash"
     misc_feature    complement(20096..20109)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.83"
                     /tool="antismash"
ORIGIN
        1 gagcgtgtcg aagtccgtga acgggtcgcc gtcgatcacg gtggcgtcgg cgagcttgcc
       61 gacctccagc gtccccaggt cccgttccgc cccgaacgcc cgcgccggca gcaccgtcgc
      121 cgtccgcagc gcctgggcgg gcgtcagccc gtaccggtgg agggcgcgca gcccgaggtg
      181 gagggagagg ccgacgggga cgagcggggc gtccgtgccg agggccacga cgccgccgcc
      241 cgacagcacc ttccggtaga cgtcgatctc gcggcgcagc gtggtcagct ggtcgtccgt
      301 gggcgccttc gcggcggtct gccggacggt cgccacgtcc cacggcggca tcagcacggt
      361 gacgcggggg tcctcggcca ggtccggggt ctcgccgagc agggggacgg aggtgaagat
      421 cgtggcgatc atgcggaagt cggtgccggt gtagatctcc gtcaggtcct ggtacgcccg
      481 gccggtggcc gtcgtggcgt ggccgaactc gagccgctgc gtcgcctgga ggtgcgtggt
      541 gaggtcctgc cccagctgga cgcccggcga gcacaggtgg ctgcccgtgc gcaccccgag
      601 ccgttcgtgc gcgaatcggg ccgcctcgcg catgacccag cccggcgcgc ggacgtacgt
      661 cttgacgaag tcccagtcca gggcggtcgc gcgggtcagg gagcggcgca gtccctcctc
      721 ggtgcggtgg gcgcggccca tggtgtaggc gacgcgcggg ccgtccagca gctcgcccgc
      781 cgtcagcagc ctcggcccgg ccagcgcgcc ggccgccacg gcctcgcgga tgcgggcctg
      841 ctcgtaggcg aagccgccga gggagacggc cgtggtgatc ccgtaggcca gctggagggc
      901 ggtctggcgg ccgccgtagg tgtactgcca ggggtgggtg tgggcgtccc agaggccggg
      961 gatcacggtc tggtgcgagg cgtcgacggt ccgcagggcg ggccggcggg cccggcgggg
     1021 ctcgacggcg gcgatccggc cgtcgcggac gagcaggtcg acgtcctcgc ggacggtcgt
     1081 gcccgtgccg tcccagaagc ggcccgcgcg cacgacggtg tcggcggggg tggggcggcg
     1141 gtagtcgagg gcgacgggga cggtgcgggc ggtgccgtcc gccacgtcca gcagccgcag
     1201 ccgcccggcg gacaggtaga ggatccggcg gccgtcggcg gaccaggagg ggtggtcggc
     1261 ggcctcgtcg gtcagccggc gcggctcgcc gtcgggcgtg ccgtcggcgc gtacgggcag
     1321 cagccacagc gccgattcgt tgatcacggc catcgagcgg ccgtcgggcg accagacggg
     1381 cccggagtcg tagcggtcgg agaccgaggc gtgcggggcg agggcgtgca gccgggcggc
     1441 tccgctgtcg gcgtcgacga ccctgatcag gttgtagccc tcgcggaacc gctggttgag
     1501 gcggttgcgg tcgcacaggg cgacgaagcg cccgtcgggc gaccaggtgg gccggcccgg
     1561 caggccgccc gcgcccatgg gggccgccag cagcttctcc gtgcccgccg ccagatcgcg
     1621 gacgatgagg ttgccggaca tgtcgacgca ggccaggcgg gtgccgtcgg gggagagcgc
     1681 cgggtggacg cgcccgccgt cggccagcac ggtctcctcg ccggaggcga ggtcgcggcg
     1741 gcggacggcg tagagcccgt cgcggtcgtc cgtgaagatc agcgcccggc cgtcgcgggt
     1801 ccaggtgggg gccatgacgt accgcccggg ggaggcggcg agaacctgcc ggggccggtc
     1861 gcccttgtcg atctccgcga cccagagggc gttgagggcc gcgaaggcca cctgacggcc
     1921 gtcgggggag agggcgggca gatggagcga gcggacgcgg cggacgaccg cgccggtgtc
     1981 cgcgaagtcg taccgcttga cctcgtagcg gggccggtcc aggggcagct cggcgtggaa
     2041 ggggatggtc gccgccggta cgccccgggc gccggccggg ggcgtgggcg cgggggcggc
     2101 ggaggggtgg gggagggagt cggcggcggg tgcccggggc ggctcggggg cggcgccggg
     2161 tctgatgatc gtgaactgtc cgccgacggt cagcagcagc tcgtcgcggg agacccagcg
     2221 cggcggcacg ggctccacgt cgccgtcgac gggcacgacg gccccgtcca cgacgaggac
     2281 gcaggtcgcg gtgggcgcgg ccgtcgtccg cagataggcc agccgcccgg tgggcgagac
     2341 ggccggcgtc atgatctgcg cgccggccgc gccctcggcg cgctcgacgc gcaccggccc
     2401 ccgcccgtcg gccgccacgg acgcgaccgt acgggcctgg agcgcgcccc cggtcacctg
     2461 gccccggacg aacagcagcc gcttgccgtc ctgcgaccag acggggtcga agtcctccca
     2521 cgccccgtcc tgcccgggcc cctcctgccc gtcgcccccg gtgatccgcg tcagcgcgcc
     2581 cgtccgtacg tcgaccaccc acacccggta ggggctgccc gccacagggt cgcccccgcg
     2641 ctcggacgcg aacgcgatcc gcgtcccgtc cggcgaccag gccggtcccc ggtcgtccca
     2701 cggcccgtcc gtcacctgcc gcagcccgga gccgtcgggc cgcagggtcc agatgtggaa
     2761 gccgccgccc cggtaggcgc agacggccag cagccgcccg tcgggcgagt aggccggtct
     2821 ggtcggctcg agatcggccg gggtgatcgc gacggcctcc ccgccctcgc gcggcacgga
     2881 ccacagcacg ttctgcacct cgacgaccag ccgcccgccg cccggcgcga gcgacccggc
     2941 gccattggtg gcggccgtga acgacagcgc gccacccttg gcgcgtgggg ccgccaccgc
     3001 ttctatcgcg tccacgggca gcgcgacggc cgcaccggcc acggcggcgg taccggccgc
     3061 cgcctgaaga aaaccgcgtc gggagaaggt ggtgtccaac tgtcctcctg ggtcggggga
     3121 gttgcacggg gcggcagccc ccatggcgga agccgatggt tgcacgcccc acaggccatg
     3181 ggtcaacacc ctgggccgat cacgaacccc cgccaggccc gtttcccggg gtgcccacgt
     3241 ggcacccccc accgccgacc tccgggggcg ggggattctt catccgaacg ggtaacccac
     3301 gtcacacccc cgcggggccc gcgtcgtgcc ggaggggggg cggcgcaagg ggtgagcgag
     3361 caccgcgcga agtgcggtat tgttctcatg cgcggtcggc gagggcgaaa gcccgggccg
     3421 gacgagcacc gggacgtggc gcagcttggt agcgcacttg actgggggtc aaggggtcgt
     3481 gggttcaaat cccgccgtcc cgacacggtg aaagaagcct ctgatcagcg ggaaaccgca
     3541 ggtcagaggc tcttttcgta tgcgtcagcg gacgagccgc aggtgccgaa caggcgcggg
     3601 ctctgggacc agtttgggac cagcggcctc tcggcggccg tcggtgaggt agcggctgag
     3661 ggcggcgccg gccaggtgga tcgaccggcg gtcggggtgc aggtaccgct gagtggtggt
     3721 gatcgaaccg tgcccggcga tcacgcggag cacgtgcacg gggattccgg cgtccgccat
     3781 ccacgtcagt ccggtgtgcc ggaggtcgtg gcggcgcagg tgctcgtagc cgaggcggac
     3841 gaccacctcg tcccagtggg tggcgtcccg caggatggcg gtggtgatcc ggccaccgcg
     3901 cggtccggtg aagagccggg ccatggggtc gttcccgacg gcgtcgaggc gcgcgctgac
     3961 catgggccgg atctcgggga tgagggggac cgcccggcgt cttttgccct tggtgccctt
     4021 gtcgatgagg ccgccggggc ccggggtggt ctggcggcag cactcccagg tccaggtgcg
     4081 gcggtcgatg tcctgggcgc ggacgccgga gacctcgccg atgcgggcgg cggtgcaggc
     4141 ggagaaccgg acgacgtcgc cccagcccag gtactggtcg tgggaacgct cgacgagggc
     4201 gttggccagg tcgtcgaggg cgtcccagtc gcgcagggcc agggagcggg ggtcgtcgag
     4261 ttcgtcctcg acctgctggt acgtcctctg ccagccggtg atcttggcgg gattgacgtc
     4321 gatgatgccg tcgcggacgg cctgctccat gacccggttc agcggggcga tggagttctt
     4381 gaccgtcgag cggccgtgac cgtcggcgat ccagccgtag acggtgcggt cgacaactcc
     4441 gttggtgatg acgggcactt cgaggtgccc gatcgccggg acgacgcgca accgccagcc
     4501 cgcgccgtac gggtccatgg tcttgggctc caggccgcgc atggccaggt cccattccaa
     4561 ctcgccgtat tcggcaagcg gcatcgtcgc cacggcggga ctcacgccgc gctgcgcgat
     4621 gcgctccatc cggtcaaccc aggactgggc ttcgtcgtcc gtgggcagca tccgcgagcg
     4681 ggagaggcgc tggccggatt cggggtcgaa ccatctgacg cgggcgcgat ggggattggg
     4741 gaatccctca cggtattcca cgtccaccga cagcttgacg ccgatcggcg gaatctgctt
     4801 ctgcatcagg cggcctgcgc cgggtcgatt cggcggctga cgagccactg ctgcaggtcg
     4861 agcgcgctgt acatcacagc gcgctgcgac agctgcacga aaggcggccc ctgcggaggg
     4921 cgcgcggtgc gccaccggcg gagggtggag ggatcgcgct tgaggagccg ggcgacttct
     4981 tccgtggtgt accaactggc ggtcagagag tcgaccgaaa tctctttgct ggaggcaggg
     5041 gatatgtgcg gtgtagcgcg gtcgggcatg gtcttcctgc ggttgaacga ggatctgtgc
     5101 aaggcgaatt ccgcgagagt ttccgatcgc tgatcggctg gttccggcga gacacaacac
     5161 tgggtcgacc tcgcggaaga gtccactcaa acgggggcgc attctctgac ggagaacacg
     5221 cgcacaggac cagtttcttg accgcagtcg gttgggataa ccggcgaatg cctgctataa
     5281 atcgcgcgct acttctcgga gaggcgacgg cttcggatgg cggcgcacca gccgcaggag
     5341 gctgcgctgc cgactgacga cctgcgggat cagggcttcg gcgtagtcgg atgatgcccg
     5401 gtttctgatc acccgaggcc gaggccgagg agcgcgagcg gttgttgggg gtcgcgagcg
     5461 ttgcggcgga gggcggcagc gatgttggtg acgccggagc gtttcaggat gccgatggcg
     5521 aggttgcgcc acgtggccat cgcccggggt gcgttgccgg tccgcggtgg ggaggcgtcc
     5581 tcggcgaacg tggtgtcgcg gaggtggtgc agggactcaa tgccccagtg gtcgcggacc
     5641 agccgggcga gccgggcggg ggacgcctgc tcggcggtca ggctggtgac ggcgtagatc
     5701 gtcttgacgg tggtcttgcc ggtcttgcgg caggtacggc ggcgcttgat ctggatggcc
     5761 ttgcgggcgc cggggaacag cagcctgttc acggtggcga ccttgatccg gcggacctcg
     5821 cagcgcccgt ggccggtctc cgtcgtccga cccagaagcg ggatgtcccg ccaaggaagc
     5881 gacttgagct gcttgcggag actcttccgg ccgcccttga cagtgggcct tccggccgag
     5941 gaggtagctg gcgtgctcgc gttgggtgtg cagcgcgtcg ctggtgacca ccgtcccggc
     6001 gaggtcggcg acggtgtcga gcaggggccg gaggcaggtg atctcgttcg ttttctcgcc
     6061 gacgtccagc tgggccaggg ataggccgct ggtgtgctcc atggctgcca ggaggtggat
     6121 cttgcggccc ttcgtcctgg ccgcgccgcg caggcttttg ccgtccaccg acactccgcg
     6181 caggtcagcg ccaccgctcg gttgcgggcg gcggtcggcg agccagcggc cgaccgcccg
     6241 gtccagcgcg tctgcgttga ggcgggcccg cagtcggcgc acggcggacc aggagggcgc
     6301 cagacgccgc ggcagcagcg gatcgagccg gacgtcgagc tgttccagca catggaacgg
     6361 ggcgtcggcg atccactcac cgaccgccgc aagcgaggtc gcccctgccg gcaccgcgca
     6421 cgctgtgagg gacacgtgga aggttgggta ggacttccta cgccatttaa gggcttgcag
     6481 agaatcaacg tgttgcttca cgctccgacg gtcgttgatg tggtgtgggc ataccggagt
     6541 cgacgcgtga acaacttgct gtgaagttcg cggtgttgtt tccgcatctg gatgaacggc
     6601 agcgtcggct ggtgatgggg gccgaggcac gcatcctggg gcacggcggg atacgggctg
     6661 tcgcccgggc ggctcgggcc agtgagacca cggtccgcaa gggtgtcaac gagctggaga
     6721 cgggcgaggc ccggctgggc cgggtccgcc ggccgggcgg aggccggaag aaagcggccg
     6781 agctggaccc gggcctgcgg cccgcgctgc tggccctggt cgagcccgat atgcggggtg
     6841 atccgatgtc gccgttgcgc tggacggtga agtccacgag aacgctcgcc gccgagctca
     6901 cccgccaggg ccaccgtgcc tcagccgaca cggtcggtga cctgctgcgc gaggaaggct
     6961 tcagcctgca ggccaacgcc aagaccatcg agggcacgca gcacccggac cgggacgccc
     7021 agttccgcta cctcaacgag caggcgcgcg accacaggga caccggagac ccggtcatca
     7081 gcgtggacac caagaagaaa gagctggtcg ggcagtacaa gaacgccgga cgttcgtggc
     7141 agcccgccgg cgagccagtg atggtcaaaa cccacgactt ccctggccag gccgacaagg
     7201 cgatcccgta cggaatctac gacatgaccg cgaacaccgg ctgggtcaac gtcggcaccg
     7261 accacgacac cgccgctttc gcggtcgcct ccatccgccg atggtggcag gcccgcggcc
     7321 ggcacgacta cccaggagca cggcgattga tgatcaccgc cgacgccgga ggctccaacg
     7381 gctaccgcac ccgaggctgg aagaccggac tcgcagccct cgccgccgag accggcctgg
     7441 acatcaccgt ctgccacctg cctcccggca catcgaagtg gaacaagatc gagcaccggc
     7501 tcttctccca catcaccatg aactggcgcg gcaggcccct gaccagccac gaagtcgtcc
     7561 tccagagcat cgccgcaacc accacccgca ccggcttgac cgtgcacgcc gaactcgaca
     7621 ccggccagta ccccaccggc atccacatca gcgacgaggc catcgccgcc ttgccgatca
     7681 cacgccaccg cttccacggc gactggaact acacccttcg ccctcagctg cccctggaag
     7741 cgaccccggt cagcagcaca gcagcagacc aggcatcggc gggcacaaac cctggcctga
     7801 cgctgcattc actacaggac ccggaactga ccgggatgcc ccgccagcag ctcagcgagc
     7861 tgatcgatgc cctaatgccc cagctggaac tgcagcgtga gcgaacactc cgcatccgcc
     7921 ggggacacga gcgcctggtg gcccccggca caggcgccaa agccaagctc accccagccg
     7981 accgaatcct ggccaccgtg ctccaccagc gcaagctcgc caccatggac ctcctcggtc
     8041 agctcttcgg cgtcaccgcc atgaccatca gccgcgcgaa ccaggaagtc cgccccctcc
     8101 tggaaacgca cggacatcac atcaacgcct ccaccgcccg gttccgcaca cccgccgaca
     8161 tcaccacgtt ccttgccccc caccccaccc aaagcgagat caagtcagca tgttgattct
     8221 ctgcaagccc taagaacctc taacagaatg accactgggg tggttgaatc cgactctgcg
     8281 tcaagttgat cacgctatgg ggctggggta gctcggtcga agctgtggag attggtgaca
     8341 atctacgggc ggtggccgaa ccgctgttgc cgaaggttgg cgctccaggt tcttcctggt
     8401 ggtggacgcg cgcgtagccg atcttgatct cggcccgagg gtgggctcgg ggatcaggag
     8461 gccgaattga tggagtgcgc cagttggcgg gtttcgtcag ccgacgcgct caggggatac
     8521 gtttgcggag ctctccgggc ctgtaggcgt gttacttgac gatcccggac tgggcgatgg
     8581 tgaccttttc tctgggggtc ccgctggacg agccgaaact ctcgatcgtc ttgaccgtat
     8641 cgtagccttc gacgacctcc ccgaacacga cgtgcttgcc gtccagccac gacgcactca
     8701 cggtggtgat gtagaactgg gagccgttgg tgttctttcc tctgttggcc atcgacagga
     8761 ggcccacctt gttgtgcttg agggtgaggt tctcgtcgtc gaacgtctcc ccgtagatgc
     8821 tcttgccgcc ggtcccgttg cctttggtga agtcgccgcc ctgcagcatg aactcgggga
     8881 tgatgcggtg gaaggacgac ccggcgtagc cgaagccgtg ctggccggtg gccagctcgc
     8941 ggaagttgcg agcggtcttg gggaccacgt cgtcgtacag cttgaacacg acgcgctcag
     9001 cgtcccgcct gggcatgatg atgtcgaagt agacgttgtt catggcgcca tcctgacacg
     9061 attagctgct cttcctgagg cacctcgcct atggcgatcc gttgagcagc catggccaag
     9121 ggctcagcaa ttggcgcact cattcgccgt tcgaagcgaa caccatttcg ccccccgaag
     9181 aagtgagcga cttttgcgtc cctgtgttcc gtcccttgtg ccttggggag gggtgataga
     9241 cgagcagcgg aggctgctcg ggcatgtccg gcaggagtgg ccgcgcgagg tcctcgaaac
     9301 gtcaccaggc gcctatgagt ggcggcgttg aactgctgcc aggcggcgcc agcagatgag
     9361 tgcacacccc agggtgagga aagctttgtg gatgtcgtcg cggatctccc agcggatccg
     9421 caggcggcgg aaccagtgca agtgggcgga atgcgcgctc gacaacccag cgttgggcac
     9481 cgagtccgga gccgtgcccg gtgccccgtc gggcgatcag tggcttcacc ccaagcacgc
     9541 ggacgaggcg gcggtacttg tcgtggtcgt agccgcggtc gccgaacacg acgtccgggc
     9601 gacatggggg ccggccgcgc ttgccccgca cggacggcac cgcttcgagc agcggaatga
     9661 gctgggtgac atcgttgcgg ttgccgccgg tcagcgtgac tgcgagcggg atgccagtgg
     9721 catcaggccg gcgtgcacga cccgcgactg cgggccgact acacgaccat cgcgcggtac
     9781 atgccccgcc gtgagacaac gggctggctc gccatccggg caaccgcccc agcccactac
     9841 caggcgcact tcatcgcggg cggcgcactg atccacttca acgacgacgt ctacgaccgg
     9901 gcccctgctg accggaagac ccgtaacctg accacctggt cggcccaggt gcgcgaagcg
     9961 gtagagggca aacgcccccg gcatccgatg ctgcgcctac ctgcacaccg cgcaaacctg
    10021 cgggctgtcc ccgcaatggg ctctcgacca actggaaggc atgcacatcg acatcggctt
    10081 caccggattc accaccgaag ccgactatca ggcatacgtc gacgcggtca cctggcccgg
    10141 tgccatgatc acctccggcc tgatccccca ccaggtaccg gaccacgact tcgcccagac
    10201 ctgccgggta ctctccgacg gaatccagcg caccgacaac ctcttcgaca tggccgacga
    10261 cctgcgcgaa gggcgcatga cgctcccgac agccgacctg gaccggcacg gcgtcacccg
    10321 ccgtgaactc gccctgggcg tcgatacgcc gggcctacgc gcgttgctga cggcccatgt
    10381 gcgcaccgcc cgggaagccc tggagagggc gagccgcatg ttcgacgagg tcccccctga
    10441 gttcgccccc tccgtccgct gcctgatcgg cctgtaccac caccgcctga accaggtcgt
    10501 cgatcgcggg gtgaccatcg cccgcacccc agtgcgcgac gacccgctca cctgcctgcg
    10561 cctactggcc tccgcccgca cccccgtctt tgcctgacgg cgcgccatga caacaccatc
    10621 ccgctccaca gcggccaccg cccaccccga cctgcccggt cccggctcgg tcacctggga
    10681 acgcatgggc cggtgggcca ctctgagcgt gggcctgcgc gccctggttc tgcagaccgc
    10741 ccaccccgtc gtcggtgccg gcgtcgccga gcactccgac ttccgcgacg acttcttccc
    10801 gcggttcacc cgcaccctcg cctcaaccct gcgcttcgtc tacggcacgc cggccgaggc
    10861 cgctgccgag ggccgccggc tgcgagccct gcacgcgcgc atccgcggca ccgaccacca
    10921 cggccgtccc taccgggccc tggaccccca ggcgtacgcc tgggtccacg ccaccctctt
    10981 cgaagccgtg gtcgccctgg gccctgccct gcccggcgtt ccgccaccgc ccttggtgcc
    11041 cgccctgctg tggcgagtcg cctggccgcc catcgcacgc tatgcggtcc gggtcaccgt
    11101 ccccaccctg cccccggcct atctcgaccg actgggtctc gcctcgacca gtaccgacac
    11161 ccggcgaacc agtcggttct tcgcccgcac cgcccgcatc gaccgcctcc tcaccagccg
    11221 ctaccgctac ctgcccgccg cagcaaaagc ccgccgacaa gccgacaccg ccaacgcact
    11281 aatggcgcgt ccgtgaccga caccgcccgt tgtaccccgg agcaagtagc cggtgagctc
    11341 agcgcccgcc tccggcgcgg accatctgat acgagatctc gtccgcgcgg tgctcatcct
    11401 gcagccgttc gaaaatccgc ttcactgtgt gacgctctcg cgcggccctg acggcagcac
    11461 ggcggatcgc cgcgtacaga tcaaccttgg actccggcag caacccgccc cctcgccatg
    11521 cagagcacaa ccatggtccc gaagcaagca ctcatctgct ctcgaaactc ggcgacatca
    11581 ttctcccggg gaaagccatc ttggcgccgg gcaacaggcg ctctcgtaac tcaccgacaa
    11641 agccaaagtg cggctttccc tctcagcttg tagtttatct ggcagggtcg aaatatccct
    11701 cgagctgggg cgttcggcgt tcccgtcggc cgtcgcttcc gcgtgaagag atctagcatc
    11761 ggcgaaggtt catcatcgag cggaggcagg tcgcatgggc gtgactaggg agatcatcga
    11821 gcccggggac ggagtgaact tccccaaaaa aggggacacc gtcacgatgc actacacagg
    11881 cgtgctgacg aacggccaga agttcgactc gtcccacgac aggaatgagc cgttcaagac
    11941 tccgatcggg atcggcaaag tgatcaaagg ctgggacgag ggtgtacccc agatgtcact
    12001 gggtgagcgc gcgaggctga ccatcacgcc cgactacgcc tatgggagcg gtgccgtcgg
    12061 caaaataatc ccgcccaacg ccacactcat cttcgacgtt gagctgctga agatcaactg
    12121 agtttgcctt catccggaga cgaagcgtcc ctcgaactgg ggcgctcacc tgagtattcc
    12181 ggacacgcgg gtggcctcgg cctgatcatg tgttccgacc aaggacgcac ctgaccagac
    12241 cgaggccgtg gagacgagag tgctgcaggg ggaccggcag gaagcattcg tgaggttgtc
    12301 tcacttccgg acggagttgt acgcctgcct ggctgctcgg ggcgacgcgt tgttcgagtt
    12361 gtgtgatgcg ttgttgcgca tggacgggcc ggtgcggacg ctggtcgacc tcgcgctcgc
    12421 accggaacac cgccgcgggc acggagccct ttacggtggc ttgaaccggg gggatcgacg
    12481 tcgcccgact gcgtcgcgcg ctggccggcg atgccgctgc cgaaagcggc ggatgttcgg
    12541 atcgttctgg ccgcagatgt ctctccgtgg ctgcggccgg acgccgacac ctgcgctgac
    12601 cggtccttct gccacacgtt cggccgcggg aaaggcaagc accagatggt cccgggccgg
    12661 ccctactcga tcgtcgccgc actggagacc ggccgcacgt cctggacagc ggtactggat
    12721 gcgatccgcc tggagcccgg cgccgatgtc gccgcggtga ccacagccca gatctgcgag
    12781 gtagtcgaac ggcttgtggt cgccggccag tggaagccgg gtgatccgaa ggtcctggtc
    12841 gtctcggacg ccggctacga cgcaccccgc atcgcccact tgctgggcga gctgcccgtc
    12901 gagatcctcg gccgcctccg ctccgaccgc gtcatgcggc ggtcgactcc accgcgggtg
    12961 tgccgcccgg gccggccgcc caagcacggt ggcgagttcg tcttcggcga ctctgccacc
    13021 tggggtgcca aacaggccgt gaccgtcacc gacacccggc tttacgggaa agcgaccgca
    13081 caggcgtggg accggctgca tccgaggctg acccggcggg cggcttggct cgaccacgac
    13141 gggccgttgc ctcccatcga gggcaccgtc gtccgcctgg tcttggagaa gctgcccagc
    13201 ggcggggtga acaagccggt ctggttgtgg tggtcgggca cggcgccacc gaggacgacg
    13261 tggaccgctg ctggcagtcc ttcctccgcc gcttcgacat cgagcacacg gttcgcctgt
    13321 tcaagcagac tctcggatgg accaaacccc ggcttcgcag ttcggaggcg gccgaccggt
    13381 ggacgtctac gcggtcacga gtctcaccgc ccaccaggcc gccccggccc agcttgcgaa
    13441 gctggtccgc ggccagtgga gcatcgagtc cctgcaccac gtccgcgaca ccaccttcgc
    13501 cgagggcgca tcccaaccgc ggaccggcaa cgcaccacgc gcgatgaccg cctggcggaa
    13561 cctcgccatc ggcgccctga ggctgaacgg cgtcaccaac atcgccaccg ccctccgccg
    13621 caacgcccgt gatccacgac gcccactggc cctcctcggc ctcgcgtgat cacaaaacgg
    13681 agatcaggtg actacgccga agccctgcct gcgggatgcg tgcacggtgg gaccgcctgc
    13741 cccacgttca cggcaatcgg attgcaggcc agcatgcagc gggaaacaat ctcgcctccg
    13801 tcggccgtta aggcaggcgg aggcaagaag gggtggacgt gtcaggtctg aagttgttca
    13861 acgtcggggc gggcggcgcg gaggagattc ctgcgcgacc ggtagcgcgc gagcgatgcc
    13921 tgcaggagct ggtcgagcag cacatggaga ccttcctcgg cgtgcgcttc ctggccagcg
    13981 agtacagcac gggaccacgg cacggcggcc ggatcgactc cctcgggctt gatgagaacg
    14041 gggcgcccgt gatcattgag tacaagcgcg gccaggatgc aggtgtgatc aaccaggggc
    14101 tcttctacct gtcgtggctg attgaccaca aggccgagtt ccagcacctg gtccgcgagc
    14161 gcctcggcgc agccgccgcg gcccaggtgc tgtggaacga tcccaggctg atctgcatcg
    14221 ctgaggactt cacacgctac gacgcccatg ccatcgggga gatccagcgc acgatcgacc
    14281 tggtccgcta ccggtacttc ggcggtgacc tgctcgcgct tgagccggtc gcctccgtca
    14341 cgggacggga acgccagccg cgtcctcggc gggtcggtgc tcgtccaggt cggcacttcg
    14401 gtggtgtggc cgaagagctg agatcggccg tcggcgaggt cttggtctcc ctcggcgatg
    14461 acgtgaccca cgtggaccgt aagcaatatc gcgcctaccg gagactgcgg aatttcgcct
    14521 gtgtcagccg catgcataag cagcatgtcc ttatctatct gaatgctgac ccgggcaagg
    14581 tggatctgat ccccggtttc actcgtgatg tgacgaatgt cgggcatcac ggtacgggcc
    14641 cgttggaggt gcgccttcgt acggagaagg acctcgaacg ggccgtccct cttttccgtc
    14701 tcgggtatgc aggcgcgtaa ttggtgcgcg atcccacgcg tggcggtggc ggatggtgca
    14761 tgaactaccg cgacgaactc gatgtcggtg cacgcggggc tgagtagctg ggcccgaaag
    14821 ggttcaccgg ggcgatcctc gggggtgggc gagtcacgga gcgttgtgtc gggggccggg
    14881 aggaacgtag aggcggggcc ggcggtcgtt ggtgtgcatg gtgccgccgt agccgcacgg
    14941 cggtgaggtc tcgaagggcg cggcggcaga ccgtgatgag ttgttgtggc gtcatggtgg
    15001 ggtcgtctac cgcgagtttg atgtgttcgg cggaggcggc ggttgtgctg agcagcgcgt
    15061 ggtccaggat ccgcgtggcc cagtagtcgg gatcgttgcc ggagcgggcg caggtggtga
    15121 ggacggtttc gggggtggtg ctggcgagga ctccgcggtg ctgggcttcc cagagcacgg
    15181 tgatggggtc gatgggctcg ccgcggtgat gcaaggcggt caggcagcgg tagagctgtt
    15241 ggtggagagg gtcggcgaag tctcccgggc tgaggtagga gcggatgccc cccagttcgt
    15301 tcggtcgggt cgtgactgcg gagaggaagg cttgttcgtc ggcgtgccgt tggtcgttcg
    15361 ggggaagctc gcggagcggg ggaggggagc ccccgcgagg cgtggctccc gaatgggcgc
    15421 gccagcgccg ggatattcca gctcggcgcg ccgcttcatg gtcgaccgcc atgtcgccca
    15481 cgaaagtggc ttgcgccgga tcagcacaga gatcgacgag cgcgagcagc agaggatcgg
    15541 gggccggctt gctgcggcca ggaccgccgg ctgcgcgaac cgagccgaaa gggcacccga
    15601 gctgcgccag cagaggggcc gcacgatcca gtggcttgga cgtgacgaca ccgaggagcc
    15661 acccgcgggc gacgagagtg tggagcactt cctccacgcc atcgaacggt cgagcgagat
    15721 gggcgacggc cttcgacgct tccgagtacg tctgatgcac cgcctcggca tcggtcacgg
    15781 tcaggcgcct catgatgtcg ttgaacgggc ggcccaagtg ctgctcgtac tgttcgaacg
    15841 gcacctcgat gcggtggcgc tgctggaccg cgccccacgc cttctgcatc accggtcgtg
    15901 tgtcgagcag gactccgtcg aggtcgagga gcagcgagcg ctgtccgccg cggcgcgccg
    15961 gatcggtgtg acggctctgt atcgcggggc gaggtgtcga ggccatgttc ttctccctcg
    16021 agtccggggt gggactgccg tggttcgaaa gggcgtgccg agccttcgga tgccggtgag
    16081 agcgatgcgt ggacgatcac tcctcggccg gcagatcggg cacgctggcc gacggcgggt
    16141 tcgggacggc gttgtggtgg tgttcgagcc ggacgagctg cccgagcagc cccagcgtgg
    16201 cgaggacgcc gaccccgtac gtccacttgc acacggtgcc gacggggtcg taccaggcga
    16261 gtcggcgtcg aggccgtgca cggtcgttca tgaagcggcc gccggaaagg gctgctcgaa
    16321 gcccggctcg gcgagcgcga gagcgaggag gccgcgacag atgtgggcga gctcttgggc
    16381 gtacacacag cgcacgaccg cgggtccggt cttcggctcg ttgttcagcc tgtctcgcac
    16441 ggacgcggtc atgaggcgga tctggtcgtc ctggccgtac cgcgcccagc ccttggcctc
    16501 gatctcgggc agcagcagct ggatgtggcc gcgcaggcgc agcaacaggt gctcgacggt
    16561 ggcggccagc ggcagcctgc cgagggtgac gcggaccgtg ctcatgatgt cgtcgacatc
    16621 gatggggtag tcgacctgcc tggccggggg agcgccccgg cgagtagcgc gaggtcggcg
    16681 accagcggcg gtcttgacgg ttctcacgac acgaccaccc gcccggatgc ggtcggcctc
    16741 gcggcggatc gcgaggcggg cgcgaagccg cggaggaggg ggaagcgggg ttcgccgagg
    16801 acgcgccagc acaggcggtt gccggtgaag gattcgcggg cgtggagcca gcgctggttg
    16861 tcgatcaggt agccctggcc ggcgtccagc gggagccgga tctggtaggt ggtgagcgtg
    16921 cttcggagat ccggcaggta gctctgcacg gtggggttga agcgggcgag gccgtcgagc
    16981 ctgagccgca cggacacccg gccatcggga tgctcggtga acacctgcgt cgcgtggccg
    17041 tctccgccgc cgaagaacgc cgtgcgctcc ttgctcagcg ccacgatggc atcgcggtgg
    17101 cgtgccgcga tgtccgcgta gaccgctcgg ccgtcggtga gcaggcagtc gccgccgtgg
    17161 tgggcggggg tgccgcagac caggagcatg agccggggcg gctcggggac gccggagcgc
    17221 tcggtgtgcg gggcgagttc gccgttgccg aaacccccgt atccggcaag gcgcatgtgg
    17281 cggcgggtgt cgcggagggt ggtcagcccg tcggggtcgc tgtcgcggtg aggagtgatg
    17341 tccatgattc gggaggcgaa ctcgcgaacg acagttcggg aggtgaagcc gctgagggtg
    17401 atcatcccga tgtcgcgtaa ccgttcgcgg accacctctt cggcccgcga cgactggacg
    17461 tcgacgtagt gggccgtgaa cggcttggcc tcgcgcatca gtgcgctcct ctcctcgggg
    17521 acggtgcggc cagggtcgac tcggagcggc ggcgtggtac agcgacggat tgtcgactcg
    17581 gacaattcgc ctacgcaggc agagagttgc cgggcgcgtg ctatgttccg cacgctccaa
    17641 ggaccggcga cgcacgaagg acagcgatga cctacaagcc cccgacctgg cccgtttccg
    17701 tcaaggccgt cgctctcgac atccgccagc gcgtgctgct gctcaaaaac gaacgcgcgg
    17761 agtgggagct gcccggcggc cgcctcgagc acgacgacga cagtccggag acgacggtcg
    17821 agcgggagct gctggaggag accggctggg aggtgaagac cgggccgctc atcgacggcg
    17881 gcgtgtggat ctacgagccg atccccggcc gacgcgtgct gatcgtgacg tacggctgca
    17941 cggtgctcac cccggatcgc gagccggtcg tcagccatga gcacaagagc atcggcctct
    18001 tcacggccga cgaggtcccg gagctgaaca tgcccgacgg ctacaagcgc gccatcgcca
    18061 cctggtacgg gcagcggcag cgctgaccgg ccgccgggag gtgcgacgtc atgccgtcgg
    18121 cgccccgccc cgccgcccgc catgtggtct ggcactgggc gaccccgcag gccgaggctg
    18181 tcctcgccag ccgcgaactc ggcacgatcc tgcggttcca ccgggccgtc caccggctca
    18241 accagaccga gctcggcgag gccctgggct acgacaagac gtacgtctcg gcccttgagc
    18301 tcggcaaacg ctcgctggac gatgtcggct cccgccgccg cgtcgctgaa cggctcggcc
    18361 tgccgccgca cgtcctcggt gtgaccgacg tcgccgacac cgaccaccgg gccatggtgc
    18421 agttcgggga gtcgaccgtc cggctcgccg agatcgcccg ccagtccggc cacgcttccg
    18481 aagccgtcgc cgagctctgg cccctcgtcg cccgcctgga agcccgtgtc gaggacgggc
    18541 acagcgaacg tgacgtcgta cggctcctcg cccgtgcccg cgtgggcctc ggcgttgccc
    18601 tcggcaacgt gctccccgag gagcgactgg ccaccgcggc ccgctggacc gcccgcagtc
    18661 tggaagcggc ccgccacctc ggcgacgacc ccgccctgct ctccggcatc ctgcgcatgc
    18721 acggcaacga actgcgcaag gcccgcctca ccggcgccgc tgtcgaacgc ctgcgccacg
    18781 ccgccgccat cgcgcccacg tccgacgacc gcgccgccgt cctgccgctc ctggcccgtg
    18841 ccgccggggc catcggagac cggaacctgt tcgacacggt gatgcgcgag accgacagcc
    18901 ttctcgagcg ggccgcgcac acctcgctgt tcaaccccta ctcgctccac gagatccgcc
    18961 tgcgcggact cctggccacg ggccgcgcac cggcggcgat acggctcgtc gaggaacggc
    19021 cggcactcac gaccagggtg gcgccgcagt ggcgggtgat cgagctggtc accgtcgccc
    19081 aggtccgtct catcggcggg gaccgtgctg gggcggccga ggccctggac gtggcgctgg
    19141 gcgaagcggt ggtgcagcga ctgccgcacc aagtccagcg gatgatgcgc gccgccggtc
    19201 agcggctgcc ggacatccgg gtcgccgcag gcgaggcgct ggaccggatg cgacaggaga
    19261 tggccgcgta ggaccgcggc cgcgagcccg ctcaccggat ctgcccgggg ccgagatcgg
    19321 ggaaggggac cgcgcgggcg aggtcgtagt agacctcgaa gtcgtgggcg ggccaggtcg
    19381 tcgcatcgcc gtgcgctttc cggtaatggg ctccgacggg ggattcggcg gggctctcga
    19441 gcttctgctc cggacggggg gtgggtccgg acatggccgt gccaggaaaa acgggcatgg
    19501 ggaggctcca gcctgagcgg tctgcgggtg cggcgagtca tcgttgttca tcgcttcgag
    19561 acgatggccc accgcgttgt gtacggggga tggaagacgg tgcccaaaac cggggagaat
    19621 catggtcgtt gggccttgtg cctgggcacg gatactgcac ttcgctgcca cggctgtgaa
    19681 agcagcggat gcgtacggtc cccgggtgta cgcatcaacg gcgtggacga tgaaggagac
    19741 gcgatgccgc agtcgccgaa gccactgaac ccgacaggat cggtcaggga acggttcggt
    19801 gcccacctcc gccactggcg catggtccgg cgcctgtcgc agacgcagct cggcgccctg
    19861 gtccacgtca gcggcaacca gatcggcaag atcgaaaagg gcgagcggat atgccgggcc
    19921 ccgctggcgc gccttctcga cgccgcgctc gacacgggcg gaatcctgga gtggatgtgc
    19981 tcctacgtcg aagccgaagc ggacaacggc cggcctgatg cgtacaagac caaggacggg
    20041 acagactctg gccgtatggg tgttcccgag gcggtcatgc tgtcactcga cgatgacacg
    20101 ctgagtgaca actggagtga cgtgcgacgc cgttccttcc tcaccgctgg aggcgcaacc
    20161 gcgatagcgg cctctccctt ctcccacctg ctcgcgccca ccgagcccgc gcagctcccg
    20221 gccgtcgtgc gccttcagga catcgagcag atccaggacg ccgcgaacgt ggtctccggc
    20281 tgggacaacg cctatggcgg gggcggcatc gtccgacaag tggccaccgc acagctgaag
    20341 tgggcctctg ccctcctcga gtgccgctgc ccggagaaga tccggccgca gctgttcgcc
    20401 gccgccgcgc ggctcggcat ggtcgtcggc gccactgact tcgacgccta cgcccacgac
    20461 gacgctcgcc gcgtgttcgc cttcgccgca gcctgtgccg aggaagccgg ggaatggcat
    20521 ctgcgtgcga agatctacag cttccgcgcc cgccaggcca tctggctcga cgacggagac
    20581 accggcttga cccatgc
//
