LOCUS       NZ_CP034587            15978 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5767422
            Orig. end                         :: 5783400
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..15978
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /product="aminopolycarboxylic-acid"
                     /region_number="25"
                     /rules="AfsA"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..15978
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10960
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10960
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5960](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5960
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    complement(993..1002)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(1193..2419)
                     /locus_tag="EKH77_RS25775"
                     /old_locus_tag="EKH77_25775"
     CDS             complement(1193..2419)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742091.1"
                     /locus_tag="EKH77_RS25775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25775"
                     /product="transposase"
                     /protein_id="WP_240667531.1"
                     /transl_table=11
                     /translation="MAVHHSTRPFTPGTASLVSFAEEVFGYLPRADQRRWAHAYLEGLL
                     TTPGKKTVRRLAAAVSASPTASQSLHQFVNASPWDWGPALRSLAHWTLRRTVPRAWTIG
                     TVVVPKRGESSVGVHRRFDPASGRTVNCQFGVGIFLSTDTEPVPLGWRILLPSRWTDDD
                     TLRERARIPESSVGDRPASAQVLDLVHTLHSRTAATPLPVVADMSSCTEAASLIRGLDR
                     AGCDFVVAVPPALAVLPGGRPRGDGQDAPVPVRRLVYQGDGFGEVPAPLGAPGAAPAGQ
                     PRRLLNALVRLPERPGARTGTTTPPAYRAFARRVPGRQADEPVWVTNLTRHSAEELVAL
                     TGHHARTTGALRTLEDDFGLRDFEGRSFPGWHHHMTLVSAAFAYSRLADAAAAAAARVD
                     RPLAVVRSA"
     cand_cluster    2444..15978
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2444..15978
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[7443:10978](-)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(7444..10978)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="2"
     misc_feature    complement(2462..2477)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.95"
                     /tool="antismash"
     misc_feature    complement(2484..2497)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.14"
                     /tool="antismash"
     misc_feature    complement(2485..2498)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.44"
                     /tool="antismash"
     misc_feature    complement(2486..2499)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     misc_feature    complement(2651..2664)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.78"
                     /tool="antismash"
     gene            2660..3241
                     /locus_tag="EKH77_RS25780"
                     /old_locus_tag="EKH77_25780"
     CDS             2660..3241
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="EKH77_RS25780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25780"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_164737859.1"
                     /transl_table=11
                     /translation="MQERAVRTRSALVRAAARAFDRNGYDGTSLSQIRAAAEMSMGALT
                     FHFATKGELADAVQDEGWILTEARVRDALTPAGDPVDGLVALTLALAALMEEEPMVRSA
                     ARLTRERAGGRAWTSAWRPAAHALIERARASGVLPPVARPEVVADLVSHLIVGAEAQIR
                     ASAADAGRPAVDVGGQLARIWDLVLLPVRG"
     gene            complement(3327..4265)
                     /locus_tag="EKH77_RS25785"
                     /old_locus_tag="EKH77_25785"
     CDS             complement(3327..4265)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742094.1"
                     /locus_tag="EKH77_RS25785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25785"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_126916680.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.2e-10, bitscore:
                     38.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPLVALTGATGFIGSAALRELGRRGVRVRALTRHPGPDTDPLV
                     ERFTGDLTDPGSLRGLCEGADALLHLASCVSPDESLCEAVNHRGAVALAAEARRAAVPR
                     VVALSTAAVYGPGPHSGPDVDAIRPAPISPASRTRLAGEAPMLECGAVVLRPGLVLGAG
                     DRWVVPALAELLRRVPARWDGGRGLLSAVDVTDLARLVADLACGPHAVPAGVHHASHPV
                     PVRNGGLMDALAEHAVLPRAEADWPWQRCLESLRLNPGRMSERQFALLARDHWYASTEV
                     WRAAACAPGPGVLARLEEAAPWYRRHVAPTA"
     gene            complement(4262..4891)
                     /locus_tag="EKH77_RS25790"
                     /old_locus_tag="EKH77_25790"
     CDS             complement(4262..4891)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007264896.1"
                     /locus_tag="EKH77_RS25790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25790"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_126916681.1"
                     /transl_table=11
                     /translation="MARPRQDRAVRTRAAILHAAAEVFDELGFSGASVSKIIARADATQ
                     GAMYFHFKSKEDLARAVMNEQGEGIVMPEGEPGLQHLIDITLHLATELQSNVLLRAGVR
                     LAVEQGEFGVQDDTAYQEWAARFHEQLVAARDRGELLPEVNERELAWVLVSCYTGTQLF
                     SQVSTNRADLPERVALLWRYLLPGVATPEARARLVTGPGAAGTARR"
     gene            5001..5960
                     /locus_tag="EKH77_RS25795"
                     /old_locus_tag="EKH77_25795"
     CDS             5001..5960
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979781.1"
                     /locus_tag="EKH77_RS25795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25795"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_126916682.1"
                     /sec_met_domain="AfsA (E-value: 2e-22, bitscore: 77.6,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDLVQQAPVLSSIPSTPHGLTTCVPRQYVHKAAMAEVLLTGWER
                     VADDTFTIGAQWPRTHSFYTPVDGRYDPLLFAETVRQTIPLLSHLAYDTPFGHHLIWDH
                     FRYELDPAATAVAATPAEIELRITCSDVKRRQGRFSALVMDVTALRDGAPLGIARARFT
                     SHAPAVYRRLRGEYGDPSVVSRAVPLAPPLAPVRVGRDRFHDVVLSPTDADGVWQLRVD
                     PSHPVLFDHPVDHAPGMLLLEAARQAALAATGPDHGAVLGLETVFSQYVEFDSPCWIEA
                     TVLPQDDGALTRTRVTARQNDREAFSAVVTSTAGRSGV"
     gene            complement(6017..7444)
                     /locus_tag="EKH77_RS25800"
                     /old_locus_tag="EKH77_25800"
     CDS             complement(6017..7444)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998466.1"
                     /locus_tag="EKH77_RS25800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25800"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_126916683.1"
                     /transl_table=11
                     /translation="MPSVPAALPRLLRDSRALAVLAVPLVLTQLAQVALTTTDTVMMGL
                     LGTGELAAGGLAIVVFNQVRTMGVGLVTSVGNRVAAAAARAGTSPERAAAPGPDDEVAA
                     VARAGLAVATLAGVAGAVLMVVIGQCLSLLGQDAEVAHRARAMLVALAPGLLPCLWFQA
                     VRQFTVGMRRPQALLRITLASVAVNAGLNWVFVHGTWGLPRLGLTGIGVATSLVHLLSF
                     LALYASTRRDPVLGPCLSARVLGADRATVRRLIGLGVPIAATYGSEAGFFSLTALMAGS
                     FGSAALAAHTAVNQLVYIVFQVAVGLSHAASINVSRELALGDVAAARRLRTTALACAAA
                     VMAVVGGCYLAFPGAVLRPFLDSGAAGDGDALSIATGLLAVVAVLQFFDCAQNIGVGLL
                     RGLDDTKGGFRATLVGYWLVGLPASLLLGYAADLRTLGLWLGLLAGLATTAALLLRRYA
                     AGLRARSGAVAEAVATG"
     gene            complement(7444..8508)
                     /locus_tag="EKH77_RS25805"
                     /old_locus_tag="EKH77_25805"
     CDS             complement(7444..8508)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138038.1"
                     /locus_tag="EKH77_RS25805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25805"
                     /product="cysteine synthase family protein"
                     /protein_id="WP_126916684.1"
                     /sec_met_domain="AesC (E-value: 7.7e-173, bitscore: 572.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 1.8e-57, bitscore: 193.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAALTARPAPVPPSAAPARPAVVTRVSELIGHTPLLELCRTADG
                     SRLLLKLEMFNPMGTAKIRMARQMVLDAEARGELRPGGRIVESTSGNTGLGLAVMAAER
                     GYAFTAVVDHHASADKLRAMRALGTELVYVTDDGTDELATAAREELAESLARGRDNTIF
                     TEQHNNPSNGVGYAAVAHELHDALEGRVDVLVAAVGTGGALCGTARELRRLVPEVRTVG
                     VEPKGSIAFGGPAHDYHQSGTGTPEGAEIGALVDFSLIDEGVKVGDVEAFATCRAVART
                     GLLIGGSAGGVVHEALRRLPSLPPGSTMVALVNDGGEKYLDTVFDDGWMAARDLLDPVV
                     EREVGDLLGTLRGH"
     gene            complement(8553..9935)
                     /locus_tag="EKH77_RS25810"
                     /old_locus_tag="EKH77_25810"
     CDS             complement(8553..9935)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091639.1"
                     /locus_tag="EKH77_RS25810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25810"
                     /product="Y4yA family PLP-dependent enzyme"
                     /protein_id="WP_240667532.1"
                     /sec_met_domain="AesB (E-value: 9.8e-197, bitscore: 652.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 9.1e-23, bitscore:
                     79.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3e-06, bitscore:
                     25.9, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAVTTTRAAAAPPLPAHPDPEASAVLESGLLQELSYAFDGPF
                     HFLLPDRFDTNLAAFRAALAEAGVAGRVYYAKKANKAAVWVERCAATGAGVDVASAGEL
                     REALAHGVRGEDITVTGPAKHEQLLRVAVLQGALIAVDSPGELDRVLALTGGTTRPARV
                     LLRRLPPDQPHSRFGLDDEETAAALRRCAAAGPAVSMEGFSFHLSGYALRPRADLAGRL
                     VDECRAARALGLRADRISVGGGFAVDYAAADDWHGFLAEQRPEHYHAGKAFTAGDFYPY
                     HSPLAGAGVLRAVLATTPEGHSASLARLLRDAGVTLMLEPGRALLDRAGATVFRVLGVK
                     ERDGYAVLTVDGSSLSLSEQWFNSEYLPDPVLLTEAGPARGPAVVAACVGGATCLESDM
                     VTWRKVPLPARPREGDLLVYPNTAGYQMDSNESPFHDLPLPPKVVVDRPAGRPRWRLDR
                     HA"
     gene            complement(9947..10978)
                     /locus_tag="EKH77_RS25815"
                     /old_locus_tag="EKH77_25815"
     CDS             complement(9947..10978)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091640.1"
                     /locus_tag="EKH77_RS25815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25815"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_126916685.1"
                     /sec_met_domain="AesA (E-value: 1.4e-165, bitscore: 548.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTSPAAPAHDSHRIRDDKALTVLSTSDVAGIDITPADVLATVE
                     NAYRTLAAGRSDNPRKLTVKPGDGHSVAYAMLGRDGSRDVVAVKTSYKHGLHSPRDAQH
                     YYTTLTLYDDVTGLPLAMMDCGRIGALRTPAVSALLARECAPPGARAALVIGTGTQGRL
                     ALPFLLTALPGLERLMLHGTHPDGITAVRRQLRAYFPGRDVEIVTDLREAAGAADIVVA
                     TAGPHTPAAVEASWLRPGALAVLVGHGLAPSTLHEADRVVATSEAQMRVTGTDMADADG
                     ELPAVDAEFPAVLAGDALGRTAPDQRVFAYNSGLVVTDIALGHRFAQLALTQGLGTRVP
                     LWQ"
     gene            complement(11013..12056)
                     /locus_tag="EKH77_RS25820"
                     /old_locus_tag="EKH77_25820"
     CDS             complement(11013..12056)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (158-312). E-value: 1.3e-11. Score:
                     36.8. Matches aSDomain:
                     nrpspksdomains_EKH77_RS25820_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546195.1"
                     /locus_tag="EKH77_RS25820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25820"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_126916686.1"
                     /sec_met_domain="TauD (E-value: 1.4e-09, bitscore: 36.8,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGTAPVPAAAPSPTPAPVRLLDDASVDELHRAADEILTAFGTS
                     ATSPALLRRVRGSAAALGPSIRHQCRPVDTDAGLFVLRGLRVDDARIGATPESWRTAGD
                     AGAHHDIALLLLATVMGDPIAWEGQQEGRFVHNIVPAPGHEREQTGASSSVLLSPHTED
                     AFHPGRAHLLMLTCMRNHDAIATTAASVRRTRLDDATVEELTRPVLPILPDDAYAEAQG
                     FAGEPPRVPALWRAPDGLTLRFDPAYTPLAEATPEYRAAYRRLEDELARVSVAVSLSPG
                     EVLVVDNDLVVHGRVPFTARYDGTDRWLKRASVRVPGRRTRPAAEAGEHGYGQAAIEAH
                     AAEAPAA"
     aSDomain        complement(11121..11582)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS25820_TauD.1"
                     /evalue="1.30E-11"
                     /label="EKH77_RS25820_TauD.1"
                     /locus_tag="EKH77_RS25820"
                     /protein_end="312"
                     /protein_start="158"
                     /score="36.8"
                     /tool="antismash"
                     /translation="PHTEDAFHPGRAHLLMLTCMRNHDAIATTAASVRRTRLDDATVEE
                     LTRPVLPILPDDAYAEAQGFAGEPPRVPALWRAPDGLTLRFDPAYTPLAEATPEYRAAY
                     RRLEDELARVSVAVSLSPGEVLVVDNDLVVHGRVPFTARYDGTDRWLKRA"
     misc_feature    12194..12212
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.57"
                     /tool="antismash"
     misc_feature    12221..12236
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.07"
                     /tool="antismash"
     misc_feature    12328..12346
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 28.57"
                     /tool="antismash"
     gene            12389..13936
                     /locus_tag="EKH77_RS25825"
                     /old_locus_tag="EKH77_25825"
     CDS             12389..13936
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138034.1"
                     /locus_tag="EKH77_RS25825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25825"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_240667533.1"
                     /transl_table=11
                     /translation="MDFTRRQMLLAGAALGSAALLTACQDGGGTASAGAGNQPRPGGTL
                     RVGALGRASAITRDPHGNQGNESDYLVIALVYDTLTAPGAKANTVGRLAASWTPSDDLR
                     TWRFTLAKGAVFHDGTPVTADDVVWSLRRLRGTPAGAARLPGITAENITADGKDTVVLV
                     SGYANAELPLLTRLSTFVLKKDTAEADLPKAPGTGPFVLDWYRNGNARLVRNEHWHGGT
                     VLLDAIEVTMFESPQALANAVLAGQIDLASNAGAVAGRTAAARKDIQVVRRPDDMAMPI
                     VMRTSEGSPFADPRVREAFKLVVDRPAMVKQTLSGYGTVANDVLGTADPAYAKDIPQRA
                     RDLDKAKRLLKEANFDLGRTYELVTTEDVAGLAESATLFAAQAREAGIKVEVVKQESGT
                     FYDRTWLKGDFYTNYWGTNDSVVFFASKTLVTGAGQNEANFSDKDFDAAYREVLATKDA
                     GERGRKLRELQRIEHERSGYLLWGMADGIDLAAAKVRGLPRLPGYGRVQLENAWLAR"
     gene            13933..14874
                     /locus_tag="EKH77_RS25830"
                     /old_locus_tag="EKH77_25830"
     CDS             13933..14874
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173874.1"
                     /locus_tag="EKH77_RS25830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25830"
                     /product="ABC transporter permease"
                     /protein_id="WP_240667534.1"
                     /transl_table=11
                     /translation="MTPGIPRAAALLGRRLLLLVVLLAGVFAAIELLPGDAASAASDRG
                     ETAAGLAARRHLLGLDRPLPERFWDWITALPTGDLGTSARGQHVTDLLSAPFPNTLLLG
                     GAALVLTVLLSLTLGCLAAARPGGPVDRIVDVTATAAFALPEFVVSVGLLLVFSLWTGW
                     LPAATLTGADGGPADWTMLVMPVLALTLPQTGWNTRVVRAALADQAATPHVEAAALDGL
                     PAHRVLLRHALPGALPAVATGFATSTGMLLGGAVVVETLFNYPGIGTVLAGAVADRDTP
                     VIAGVVACAAAVITVVLLLADLVRARTVGTRP"
     gene            14871..15035
                     /locus_tag="EKH77_RS34595"
     CDS             14871..15035
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS34595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_346429072.1"
                     /transl_table=11
                     /translation="MSAPGLRALPAALALLALSGPLLAPHPVDTPVTAPTRGPATARPS
                     AATNWAGTS"
     gene            15083..15667
                     /locus_tag="EKH77_RS25835"
                     /old_locus_tag="EKH77_25835"
     CDS             15083..15667
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955054.1"
                     /locus_tag="EKH77_RS25835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_25835"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_346429073.1"
                     /transl_table=11
                     /translation="MAVTVTLLAAALGCLAVLSPRVGAVVERTADLVILVPPVLGLMLL
                     ALAWPGGRRLAVTTAAVVLGTPYAVRVVAAAAAPLAGAGFVEASVASGERLWRVAFHEI
                     LPNLRATILALFGLRFVEAVYVISMAGFLQLGPQPPEADWALMIRENAPGILLNPWATI
                     APAIAIAAVAIATSLATEALAPRRGGEVAAR"
ORIGIN
        1 ttcacccacg ccgaggcgct gcccggctac gacaccagcc cccgcgtcgc cgagcgggcc
       61 gccgagctcg tcgagcgctt cggcgtgacc gacatcgtcg cctgccagga gaacgacctg
      121 gagcgcgccg cccggctgcg cgtgcgctac ggcctgcccg gcccgcgccc cgaggacgtc
      181 gtgccctacc gcgacaagtg ggagatgaag cgcgccgccg tccgcgccgg catccccgtc
      241 gccgaccacg cgctcctggc cgcccccgag gacctcacgg acttcgtcgc cgtccacggc
      301 ctgcccgtgg tcgtcaagcc ccggcgcggc gccggctcca tcgacctggc cgtgctgcgc
      361 accgccgacg aggtcaccgg ctggctcgcg ggcgaccacc tcgccgcgcc gggcgaggaa
      421 cccacctggc tggtggaggc gttcgtcgag ggcggcatgt gccacatcga cggcgtggtc
      481 ctcgacggtc gcgtcgtcac catgtggccc tcgcgctaca cctacgtcct ggccgactac
      541 acccagcgcg aggggcgcat ggacatcgcc ctggacgccg acgacccgct gcgccaccgg
      601 ctgacggcct tcggcgagcg gctgctggcg gagttcgggg gcagcgagca cttcgccttc
      661 cacatcgagg tgttccacac cccggacgac gagctggtgc tgtgcgaggc ggcctgccgc
      721 gccggcggcg cgggcgtccg ggacgtccac cgcgcgatgt tcggcttcga cccggccgag
      781 ccgccggtcc gccgtcagct ggggctggac ttcccctacg agggcggcgg gaagccggag
      841 cgcgtcggcg gtcagctgct gttcacgcgg cggcccggca cggtccaccg gttgcccgac
      901 ccggcgggga tgcccgaagg ggtggtgaag caccagtact tcgcggcgcc gggggaccgg
      961 atggaggagg cctggcactc cggggacttc ctggccgcct tcgtggtggc gggcgcggac
     1021 cgcgcggagt gcgaagcgcg gatacgggcg ctggaggagt ggttcctcgc ggggctcgac
     1081 gtccgctgag cgggcggggc gtgggcgtgg cacgtacggt ccggcgcggt cggtcgctcg
     1141 ggaccggcgg ccgggcccgg gcggtggtcc gccggggccg cgcggcgggt cgtcaggccg
     1201 accggacgac ggccagcggc cggtccacgc gcgcggcggc cgcggcggcc gcgtcggcca
     1261 gccggctgta ggcgaaggcg gcggagacca gcgtcatgtg gtggtgccag ccggggaagg
     1321 accggccctc gaagtcccgc agcccgaagt cgtcctccag ggtccgcagg gcgccggtcg
     1381 tccgggcgtg gtgcccggtg agggccacga gttcctcggc ggagtgccgg gtgaggttgg
     1441 tgacccacac gggctcgtcg gcctgccggc cggggacgcg gcgggcgaac gcccggtacg
     1501 ccgggggcgt cgtcgtgccc gtccgggcgc cgggccgctc cggcagccgg accagggcgt
     1561 tgagcagccg tcgcggctgc ccggccgggg ccgcgccggg ggcgcccagg ggggcgggga
     1621 cctcgccgaa gccgtcgccc tggtagacca gccgccgcac ggggacgggc gcgtcctggc
     1681 cgtcgccgcg cgggcgtccg ccgggcagca cggccagggc ggggggcacg gcgacgacga
     1741 agtcgcagcc ggcgcggtcg agtccgcgga tcagtgaggc cgcctccgtg caggagctca
     1801 tgtcggcgac gacgggcagc ggggtggcgg cggtccggga gtggagcgtg tggaccaggt
     1861 cgagcacctg cgccgaggcg ggccggtcgc ccacgctgga ctccggtatg cgggcccgct
     1921 cgcgcagggt gtcgtcgtcg gtccagcggg agggcagcag gatccgccag ccgagcggca
     1981 ccggctcggt gtcggtggac aggaagatcc ccacgccgaa ctggcagttg acggtgcggc
     2041 ccgaggcggg gtcgaagcgg cggtggacgc ccaccgagct ctcgccgcgc ttggggacga
     2101 ccaccgtgcc gatcgtccag gcccggggga cggtccgccg cagggtccag tgggcgagcg
     2161 agcgcagggc cggtccccag tcccacgggc tggcgttgac gaactggtgg agcgactgcg
     2221 aggccgtggg cgaggcggag acggcggccg ccaggcggcg gaccgtcttc ttgcccgggg
     2281 tggtgagcag cccctccaga taggcgtggg cccagcgccg ctggtcggcg cggggcaggt
     2341 agccgaagac ctcttcggcg aaggagacga gtgaagcggt gcccggggtg aacgggcggg
     2401 tcgaatggtg cacagccatc gcacggtccc ttctgacgcg gacggcagag cccggccgcg
     2461 agcgaaagaa tagagaacga tcgctttgtt ttcaaaaccc ccggggtgtg accttcgaaa
     2521 ccgggaagga gtgccgagcc cgacgatcat ggccgtaagg tggttgaacg ccggtcttcc
     2581 accggcaagt tgaagccgtc gttccgcaat ggcgcggtcc catggcccat ggcggtgaat
     2641 gtctggaggg agcatggtca tgcaggagcg cgccgtacgg acccgttcgg cgctcgtccg
     2701 ggccgcggcc cgcgccttcg accgcaacgg ctacgacggc acgtccctgt cccagattcg
     2761 cgcggcggcc gagatgtcca tgggggcgct gaccttccac ttcgccacca agggcgaact
     2821 cgccgacgcc gtgcaggacg agggctggat cctgacggag gcccgggtgc gcgacgcgct
     2881 gacgccggcg ggcgacccgg tggacggcct ggtggcgctc accctggcgc tggccgcgct
     2941 gatggaggag gagccgatgg tccgctcggc ggcccggctc acccgtgagc gcgccggggg
     3001 ccgggcctgg acctccgcgt ggcggccggc cgcgcacgcg ctgatcgagc gcgcccgggc
     3061 gtccggcgtg ctgccgccgg tggcgcggcc ggaggtggtc gccgacctgg tcagccatct
     3121 gatcgtgggc gcggaggcgc agatacgcgc ctcggccgcg gatgccgggc gcccggcggt
     3181 ggacgtcggc gggcagctcg cccggatctg ggacctggtg ctcctcccgg tccgcggctg
     3241 accgcgcccc gaaggggcgc ggggaactgc gcgaccagcc acgacgcacc ggcagatgcg
     3301 taccggaccg gtcggtcggc ctgcgttcac gccgtaggcg ccacgtgccg ccggtaccag
     3361 ggtgccgcct cctccagccg ggcgaggacg cccggccccg gcgcgcaggc cgccgcccgc
     3421 cacacctccg tgctcgcgta ccagtggtcg cgggcgagga gcgcgaactg acgctcgctc
     3481 atgcgcccgg ggttcaaccg caggctctcc aggcagcgtt gccacggcca gtcggcctcg
     3541 gcgcgcggca ggacggcgtg ctcggcgagg gcgtccatca ggccgccgtt gcgcaccggg
     3601 accgggtggc tggcgtggtg gacgcccgcc ggcacggcgt gcggcccgca cgccaggtcg
     3661 gcgacgagcc gcgccagatc ggtgacgtcc acggccgaca gcaggccgcg cccgccgtcc
     3721 cagcgcgcgg gcacccggcg cagcagctcg gccagggccg gtaccaccca gcggtcgccc
     3781 gcgcccagca ccagccccgg gcgcaggacc acggccccgc actcgagcat cggggcctcg
     3841 cccgccagcc gggtgcggct cgcgggcgat atgggcgcgg gccggatcgc gtcgacgtcc
     3901 ggcccggagt gcggacccgg tccgtagacg gccgcggtcg acagggcgac gacgcggggc
     3961 accgccgccc ggcgggcctc ggcggccagc gcgacggcgc cccggtggtt gaccgcctcg
     4021 cacaggctct cgtccgggga gacgcaggag gccaggtgga gcagggcgtc ggccccctcg
     4081 cacagccccc gcagcgagcc ggggtcggtc aggtcgccgg tgaaccgctc gacgagcggg
     4141 tccgtgtccg ggccggggtg gcgcgtcaac gcgcgcacgc gcacgccccg tcggccgagt
     4201 tcgcgcagcg cggcggagcc gatgaacccc gtggcgccgg tcagcgcgac cagcggcccg
     4261 ctcaccggcg ggccgtcccg gccgcgccgg ggccggtgac gagccgcgcg cgggcctccg
     4321 gcgtggcgac gccgggcagc aggtagcgcc acagcagggc cacgcgctcg ggcaggtcgg
     4381 cgcggttggt ggagacctgg gagaagagct gggtgccggt gtagcagctc accaggaccc
     4441 aggccagctc ccgttcgttc acctcgggca ggagctcgcc gcggtcccgg gcggcgacca
     4501 gctgctcgtg gaagcgggcg gcccattcct ggtaggcggt gtcgtcctgg acgccgaact
     4561 ctccctgctc gacggcgagt cggacgccgg cgcgcagcag cacattgctc tggagctcgg
     4621 tcgccaggtg gagggtgatg tcgatcaggt gctggaggcc gggttcgccc tcgggcatca
     4681 cgatgccctc gccctgctcg ttcatgaccg cccgggcgag gtcctccttg gacttgaagt
     4741 ggaagtacat cgcgccctgg gtggcgtccg cccgagcgat gatcttgctg acgctggcgc
     4801 cgctgaaccc gagctcgtcg aagacctccg cggccgcgtg gaggatggcc gcgcgggtcc
     4861 tcaccgcgcg gtcctgtctg ggcctcgcca tgaggtgact ccctgtgatc tctcgacaaa
     4921 caaaacgaac accctttatc ttacggctcc agcgtcagag acagagcagc agcagcttta
     4981 gagcgtccgg gaagtcggtt atgcacgatc tggttcagca agcccctgtt ttgagctcca
     5041 tcccctccac gccgcacggc ctgaccacct gtgtgccccg gcagtacgtc cacaaggcgg
     5101 ccatggccga ggtcctcctc accggatggg agcgcgtcgc cgacgacacc ttcacgatcg
     5161 gcgcccagtg gccgcggacc cacagcttct acaccccggt cgacggccgc tacgacccgc
     5221 tcctcttcgc cgagaccgta cggcagacca tccccctgct gtcccacctg gcctacgaca
     5281 ccccgttcgg ccaccacctg atctgggacc acttccgcta cgagctcgac cccgccgcga
     5341 cggccgtggc cgccaccccg gccgagatag agctgcgcat cacgtgcagc gacgtcaaac
     5401 gccgtcaggg ccgcttctcc gcgctggtga tggacgtcac cgccctccgc gacggcgcgc
     5461 ccctgggcat cgcccgggcc cgtttcacca gccacgcccc ggccgtctac cgacggctgc
     5521 gcggcgagta cggcgacccg tccgtcgtct cccgggccgt gccgctggcc ccgcccctgg
     5581 ccccggtgcg cgtcggccgc gaccgcttcc acgacgtggt cctctcgccc accgacgccg
     5641 acggcgtctg gcaactgcgc gtggacccca gccaccccgt gctcttcgac caccccgtcg
     5701 accacgcccc cggcatgctg ctgctcgaag ccgcccgcca ggccgcgctc gccgccacgg
     5761 gcccggacca cggcgccgtc ctgggcctgg agaccgtctt cagccagtac gtggagttcg
     5821 acagcccctg ctggatcgag gcgaccgtcc tcccgcagga cgacggcgcc ctcacccgca
     5881 cccgggtcac ggcacgccag aacgaccgcg aggcgttctc cgcggtcgtc accagcacgg
     5941 ccggccggtc cggcgtctga ggcacggtcc cggtaagggc ggacgtgaac cgccctcacc
     6001 gggaccgggg gtgtggtcag cccgtggcca ccgcctccgc gaccgcgccg ctccgggcgc
     6061 gcaggcccgc cgcgtagcgg cgcagcagca gcgccgccgt cgtggcgagg cccgccagca
     6121 gcccgagcca caggccgagg gtgcgcaggt ccgccgcgta cccgaggagg agcgaggcgg
     6181 gcagccccac gagccagtag ccgacgagcg tggcgcggaa gccgcccttg gtgtcgtcca
     6241 ggccgcgcag caggccgacg ccgatgttct gcgcgcagtc gaagaactgc aggacggcga
     6301 cgaccgcgag cagcccggtc gcgatggaca gcgcgtcgcc gtcccccgcc gcgccggagt
     6361 cgaggaacgg ccgcaacacc gccccgggga aggccagata gcagccgccg accaccgcca
     6421 tgacggcggc ggcgcaggcc agcgcggtgg tcctcagccg ccgtgccgcg gcgacgtccc
     6481 ccagggccag ctcgcggctg acgttgatcg aggcggcgtg ggagagcccc acggcgacct
     6541 ggaagacgat gtagacgagc tggttgacgg ccgtgtgcgc ggcgagcgcc gcactgccga
     6601 aggaaccggc catcagcgcc gtcagcgaga agaaccccgc ctccgagccg taggtggccg
     6661 cgatcggcac gcccagcccg atcagccgcc gcacggtggc gcggtccgcg cccaggaccc
     6721 gggcgctcag gcacgggccg agcaccgggt cccggcgcgt cgaggcgtac agggcgagga
     6781 aggacagcag gtgcaccagc gacgtcgcca cgccgatgcc ggtcagcccc agccgtggca
     6841 gcccccaggt gccgtggacg aacacccagt tgagccccgc gttgacggcc acggacgcca
     6901 gcgtgatccg cagcagcgcc tgcggccgcc gcatcccgac cgtgaactgg cgcaccgcct
     6961 ggaaccacag gcacggcagc agccccggcg cgagggccac cagcatcgcc cgggcccggt
     7021 gggcgacctc cgcgtcctgg cccagcaggg acaggcactg gccgatgacg accatcagga
     7081 cggccccggc gacaccggcg agcgtcgcca ccgccagacc ggcccgggcg acggcggcga
     7141 cctcgtcgtc cggccccgga gcggcggccc gctcggggga cgtcccggcg cgcgcggccg
     7201 ccgccgcgac gcggttgccg acggaggtca ccaggccgac gcccatggtg cgcacctggt
     7261 tgaagacgac gatcgcgagg ccgcccgccg ccagctcccc ggtgccgagc aggcccatca
     7321 tcacggtgtc ggtcgtggtg agcgcgacct gggcgagctg ggtgaggacg agcgggacgg
     7381 cgagcacggc cagggcccgg ctgtcgcgca gcagccgggg cagggcggcg ggcaccgagg
     7441 gcatcagtgg ccgcgcaggg tgccgaggag gtcgccgacc tcgcgttcca cgaccgggtc
     7501 gaggaggtcg cgggcggcca tccagccgtc gtcgaagacg gtgtccaggt acttctcgcc
     7561 accgtcgttg accagcgcga ccatcgtgct gcccggcggc agcgagggca gccgccgcag
     7621 cgcctcgtgg acgacgccgc cggcggagcc gccgatgagc agtccggtgc gggccaccgc
     7681 gcggcaggtg gcgaacgcct cgacgtcacc gaccttgacg ccctcgtcga tgagcgagaa
     7741 gtccacgagc gcgccgatct cggcgccctc gggcgtgccg gtgcccgact ggtggtagtc
     7801 gtgcgcgggc ccgccgaagg cgatggaccc cttgggctcc accccgaccg tccgtacttc
     7861 cgggacgagc cggcgcagct cgcgggcggt gccgcacagg gccccgccgg tgccgacggc
     7921 ggcgacgagc acgtccacgc ggccctccag ggcatcgtgg agctcatggg cgacggccgc
     7981 gtaaccgacg ccgttgctgg ggttgttgtg ctgctcggtg aagatcgtgt tgtcgcgtcc
     8041 ccgggcgagg ctctcggcga gctcctcccg ggcggcggtg gccagctcgt ccgtgccgtc
     8101 gtcggtgacg tacacgagct cggtgcccag cgcgcgcatc gcgcgcagtt tgtcggcgct
     8161 ggcgtggtgg tcgacgacgg cggtgaaggc gtagccgcgc tcggcggcca tgacggccag
     8221 gccgagcccg gtgttgccgg aggtggactc gacgatccgg ccgcccgggc gcagttcgcc
     8281 ccgggcctcg gcgtccagca ccatctgccg ggccatccgg atcttggcgg tgcccatggg
     8341 gttgaacatc tccagcttca gcagcagccg gctgccgtcc gcggtgcggc agagctccag
     8401 gagcggggtg tggccgatga gttcggagac acgggtgacc acggcgggcc gggcgggcgc
     8461 ggcggacggg ggaaccggcg cggggcgggc ggtgagtgcc gcgttcatgg atcaggggct
     8521 cctgtcgggc ttgtacgtga cgggcggagg ggtcaggcgt ggcggtcgag gcgccagcgc
     8581 ggccgtcccg ccggacggtc gacgacgacc ttggggggca gcggaaggtc gtggaagggc
     8641 gactcgttgg agtccatctg gtagccggcc gtattcgggt agaccagcag atcgccttcc
     8701 cggggccggg cgggcagggg caccttgcgc caggtgacca tgtcggactc caggcacgtc
     8761 gccccgccca cgcacgccgc gacgacggcg gggccccggg ccgggccggc ctcggtgagc
     8821 agcacgggat ccggcaaata ctcgctgttg aaccactgtt ccgagaggct gaggctgctg
     8881 ccgtccacgg tgaggacggc gtagccgtcc cgctccttga cgcccagcac ccggaagacg
     8941 gtcgcgcccg cccggtccag cagggcgcgg cccggctcca gcatcagggt cacgcccgcg
     9001 tcgcggagca gccgggcgag gctcgcggag tgcccctcgg gggtggtggc cagcacggcc
     9061 cgcaggacgc ccgccccggc gagcggggag tggtaggggt agaagtcgcc cgccgtgaac
     9121 gccttgcccg cgtggtagtg ctcgggccgc tgctcggcga ggaagccgtg ccagtcgtcg
     9181 gcggcggcgt agtcgacggc gaagccgccg ccgacgctga tccggtcggc gcgcaggccc
     9241 agggcccgcg ccgcccggca ctcgtcgacg agccggccgg ccaggtcggc gcggggccgc
     9301 agggcgtaac cggacagatg gaagctgaag ccctccatgc tcacggccgg gccggcggcc
     9361 gcgcagcggc gcagggcggc ggccgtctcc tcgtcgtcga gcccgaagcg gctgtgcggc
     9421 tggtccggcg gcagccggcg cagcagcacc cgggccgggc gggtcgtccc gccggtcagg
     9481 gccaggacgc ggtccagctc accgggggag tcgacggcga tgagggcgcc ctggagcacg
     9541 gcgacgcgca gcaactgctc gtgcttggcg gggccggtga ccgtgatgtc ctcgccgcgc
     9601 accccgtggg cgagggcctc gcgcaactcc ccggcggagg cgacatccac gcccgcgccc
     9661 gtcgccgcgc agcgctcgac ccacacggcc gccttgttgg ccttcttcgc gtagtacacc
     9721 cggcccgcca cgccggcctc ggcgagggcg gcgcggaagg cggcgaggtt ggtgtcgaag
     9781 cggtcgggga ggaggaagtg gaacggtccg tcgaaggcgt aggagagctc ctggagcagc
     9841 ccgctctcca gtaccgccga cgcctcggga tccgggtggg cgggcagcgg aggggcggcc
     9901 gccgcccggg tcgtcgtcac tgcggtggct gtcaccgcgg tggttgtcac tgccacagcg
     9961 gcacccgcgt tcccaggccc tgggtgaggg cgagttgggc gaaccggtgg ccgagcgcga
    10021 tgtcggtgac gaccaggccg ctgttgtagg cgaagacccg ctggtccggc gcggtgcgcc
    10081 cgagggcgtc cccggcgagg acggccggga actcggcgtc gacagccggg agttcgccgt
    10141 cggcgtcggc catgtcggtg ccggtgacgc gcatctgggc ctcgctggtg gccaccacgc
    10201 ggtcggcctc gtggagggtg gagggtgcca ggccgtggcc gacgaggacg gccagggcgc
    10261 cgggccgcag ccaggacgcc tccacggcgg cgggggtgtg gggtccggcc gtggcgacga
    10321 cgatgtcggc ggccccggcg gcctcccgca ggtcggtgac gatctccacg tcccggccgg
    10381 ggaaatacgc gcgcaactgg cggcggacgg cggtgatgcc gtcggggtgg gtgccgtgga
    10441 gcatcagccg ctccaggccc ggcagcgccg tcagcaggaa cggcagggcc agccggccct
    10501 gggtgccggt gccgatcacc agcgcggccc gcgccccggg cggcgcgcac tcgcgggcca
    10561 gcagcgcgga gacggcgggg gtgcgcaggg cgccgatccg gccgcagtcc atcatcgcca
    10621 ggggcagccc ggtgacgtcg tcgtagaggg tgagggtggt gtagtagtgc tgcgcgtcgc
    10681 gggggctgtg gaggccgtgc ttgtacgagg tcttgacggc gacgacgtcg cgggagccgt
    10741 cgcggccgag catcgcgtag gcgacggagt ggccgtcgcc gggcttgacg gtgagcttgc
    10801 gcgggttgtc ggagcggccg gcggcgaggg tgcggtaggc gttctccacg gtggcgagga
    10861 cgtcggcggg cgtgatgtcg atgcccgcga cgtcgctggt ggacaggacg gtcagggcct
    10921 tgtcgtcgcg tattcggtgg gagtcgtggg ccggggcggc gggggaggtg tccgtcatgg
    10981 gcggttccct tcggatccgt gtgggggcct ggtcaggcgg cgggggcctc ggcggcgtgc
    11041 gcttcgatcg cggcctgtcc gtagccgtgc tcgccggcct cggcggcggg gcgggtgcgg
    11101 cggccgggga cgcggaccga ggcgcgcttg agccagcggt cggtaccgtc gtagcgggcg
    11161 gtgaagggca cccggccgtg gacgacgagg tcgttgtcga cgacgaggac ctcgccgggg
    11221 gagaggctca cggccacgga gacgcgggcg agttcgtcct ccagccgccg gtaggcggcc
    11281 cggtactcgg gggtggcctc ggccagcggg gtgtaggccg ggtcgaagcg cagggtgagg
    11341 ccgtccgggg cgcgccacag ggcggggacg cggggtggct ccccggcgaa gccctgggcc
    11401 tcggcgtagg cgtcgtcggg caggatcggc agcaccggcc gggtgagctc ctcgacggtg
    11461 gcgtcgtcca gccgtgtccg gcggacactg gccgcggtgg tggcgatggc gtcgtggttg
    11521 cgcatgcagg tgagcatcag cagatgggcg cggccggggt ggaaggcgtc ctcggtgtgc
    11581 gggctgagga gcacgctgct gctggcgccg gtctgttccc gctcgtgccc gggggccggg
    11641 acgatgttgt ggacgaagcg gccctcctgc tggccctccc aggcgatggg gtcgcccatg
    11701 acggtggcca gcaggagcag ggcgatgtcg tggtgggcgc cggcgtcgcc ggcggtgcgc
    11761 cagctctccg gcgtggcacc gatccgggcg tcgtccacgc gcaggccgcg caggacgaac
    11821 aggccggcgt cggtgtccac gggccggcac tggtgccgga tggacgggcc gagggcggcg
    11881 gcggaccccc ggacgcgccg caggagcgcg ggggaggtgg cggaggtgcc gaaggcggtg
    11941 aggatctcgt cggcggcgcg gtgcagttcg tcgaccgagg cgtcgtcgag caggcggacg
    12001 ggggcgggag tgggggaggg tgcggcggcg gggacgggtg cggttcccgt gctcatggcg
    12061 cgatcttccg ttccgtagcg gggtgtggga gtccgaaggg gcgacgcggg cgtacgggca
    12121 tgggggagag gggcggaggg tgggggccgc cggcccgtgg cgtcggggac tggccagaac
    12181 gtaccgttag aagttaggta aggcaaacct aactcgcggg ttatccgttt ggtccgcctt
    12241 ccgggtgatg agccctggaa tcaagggggt tgaggtcctg gccgaaatcc atgcatcgac
    12301 cagacgggtt tgcgatgccg ggtgtggtta gggtaggcaa acctaagtag ctcggaagtg
    12361 accccccatc tgccggatcg aggacgacgt ggacttcacc aggcgccaga tgctgctggc
    12421 cggagcggcc ctgggctccg ccgcactgct caccgcctgc caggacggcg gcggtacggc
    12481 ctccgccggc gccggaaacc agccgcgccc cggcggcacc ctgcgcgtcg gcgcgctggg
    12541 ccgggcgtcc gccatcaccc gcgacccgca cggaaatcag ggcaacgaga gcgactatct
    12601 cgtcatcgcc ctcgtgtacg acacgctcac cgcccccggt gcgaaggcca acacggtcgg
    12661 ccgcctcgcc gcctcctgga ccccctccga cgatctgagg acctggcgct ttaccctcgc
    12721 caagggcgcc gtcttccacg acggcacccc cgtcaccgcc gacgacgtcg tctggtccct
    12781 gcgcagactg cggggcaccc ccgccggcgc cgcccggctc cccggcatca cggcggagaa
    12841 catcacggcc gacggcaagg acaccgtcgt cctcgtctcc ggctacgcca acgccgaact
    12901 ccccctgctc acccggctct ccaccttcgt cctgaagaag gacaccgccg aggcggacct
    12961 gcccaaggcg cccggcaccg gcccgttcgt cctcgactgg taccgcaacg gcaacgcccg
    13021 cctcgtgcgc aacgagcact ggcacggcgg cacggtcctc ctcgacgcca tcgaggtgac
    13081 catgttcgag agcccccagg ccttggccaa cgccgtgctg gcgggccaga tcgacctcgc
    13141 ctccaacgcc ggcgccgtcg ccggccgcac ggccgccgcc cgcaaggaca tccaggtcgt
    13201 ccgccgcccc gacgacatgg ccatgcccat cgtcatgcgc acctccgagg gcagcccctt
    13261 cgccgatccc agggtccgtg aggcgttcaa gctcgtcgtg gaccgcccgg ccatggtcaa
    13321 gcagacgctc tccggctacg gcaccgtcgc caacgacgtc ctcggcaccg ccgaccccgc
    13381 ctacgccaag gacatccccc agcgcgcccg cgatctggac aaggcgaaac ggctgctgaa
    13441 ggaggcgaac ttcgacctcg gcaggaccta cgagctcgtc accaccgagg acgtcgccgg
    13501 cctcgccgag tccgccaccc tcttcgccgc ccaggcccgc gaggccggga tcaaggtcga
    13561 ggtcgtcaag caggagtccg gcaccttcta cgaccggacc tggctcaagg gcgacttcta
    13621 caccaactac tggggcacca acgactccgt cgtcttcttc gcctccaaga ccctcgtcac
    13681 cggcgccgga cagaacgagg cgaacttctc cgacaaggac ttcgacgccg cctaccgcga
    13741 ggtcctcgcc accaaggacg cgggcgagcg cgggcggaag ctgcgcgagc tccagcggat
    13801 cgagcacgag cgctccgggt atctgctgtg gggcatggcc gacggcatcg acctggcagc
    13861 cgcgaaggta cgcggcctgc ccaggctgcc gggctacggg cgtgtccagc tcgagaacgc
    13921 ctggctcgcc cggtgacacc cggcataccg agggcggccg ctcttctggg gcgccgactg
    13981 ctgctgctcg tcgttctcct ggccggagtc ttcgccgcga tcgaactgct gccgggcgac
    14041 gcggcgtcgg ccgcgtccga ccgcggcgag accgccgccg gcctcgccgc gcggcggcac
    14101 ctgctcggcc tggaccggcc cctccccgaa cgcttctggg actggatcac cgccctgccc
    14161 accggcgacc tcggcacctc cgcgcgcgga cagcacgtca ccgacctgct gtccgcgccc
    14221 ttccccaaca ccctcctgct gggcggcgcc gcgctcgtcc tcacggtcct gctgtcgctg
    14281 accctcggct gcctggccgc cgcccggccc ggcggacccg tcgaccggat cgtcgacgtc
    14341 accgccaccg ccgccttcgc gctccccgaa ttcgtcgtct ccgtcggcct gctgctcgtg
    14401 ttctcgctgt ggacgggctg gctccccgcc gccaccctca ccggcgcgga cggcggaccc
    14461 gccgactgga cgatgctcgt catgcccgtc ctcgccctca ccctgcccca gaccggctgg
    14521 aacacccgcg tcgtccgcgc ggccctcgcc gaccaggccg ccacccccca cgtcgaggcc
    14581 gccgccctcg acgggctgcc cgcccaccgg gtgctgctgc gccacgcgct gcccggcgcc
    14641 ctgcccgccg tcgccacggg cttcgccacg tccaccggga tgctgctcgg cggggccgtc
    14701 gtcgtcgaga ccctcttcaa ctacccgggc atcggcaccg tcctggccgg agccgtcgcc
    14761 gaccgcgaca cgcccgtcat cgccggggtc gtcgcctgcg ccgccgccgt catcaccgtc
    14821 gtgctcctcc tcgccgacct cgtccgcgcc cgcaccgtag gaacccgccc atgagcgccc
    14881 ccgggctccg tgccctgccc gccgccctgg ccctactggc cctgagtggc ccactcctgg
    14941 ccccgcaccc cgtcgacacc cccgtcaccg cccctacgcg gggcccggcg acggcgcggc
    15001 cctcggcggc gaccaactgg gccgggacgt cctgagccga ctcctccacg gcggcgacgc
    15061 cctcatcgcc ggcgcgctcg ccgtggccgt gaccgtcacc ctcctcgcgg ccgcgctggg
    15121 ctgcctcgcg gtgctcagcc cccgcgtggg cgcggtcgtc gaacgcaccg ccgacctggt
    15181 catcctcgtg cccccggtcc tcggcctcat gctcctcgcc ctcgcctggc ccggcggccg
    15241 gcgcctggcc gtcacgaccg ccgccgtggt gctgggcacc ccctacgccg tgcgggtcgt
    15301 cgccgcggcg gccgcgccgc tggccggcgc gggattcgtc gaggcgtccg tcgcgagcgg
    15361 cgagcggctg tggcgcgtcg cgttccacga gatcctgccc aacctgcggg ccacgatcct
    15421 ggcgttgttc ggcctgcgct tcgtcgaggc ggtctacgtc atctccatgg ccggcttcct
    15481 ccaactcggc ccacaaccac cggaagccga ctgggccttg atgatccgcg agaacgcgcc
    15541 ggggatcctg ctgaaccctt gggccacgat cgctcccgcg atcgcgatcg cggcggtggc
    15601 gatagccacg agcctcgcca cggaggccct cgccccgcgg cgcggcgggg aggtggcggc
    15661 acgatgacga cgcactcgcg ggggaagggg ccggggtctg gtgggcctgg cgggtcgggt
    15721 gcgggcggcg gtgaagcccc gctcgtcacc gtcgccgggc tcgaagtggg catccccggc
    15781 ggaccgttgt tgctggcttc cgccgggctc accctgcggc gggggcggat caccgtgctg
    15841 accgggcctt ccgggtccgg taagacgacc ctgctccggg ccgttctcgg cgacttgccg
    15901 tcgggggcgc gcgtggcgcg cgggggcgtg cgcgtcctgg gggaggacgt gttcgccctg
    15961 ccgcccgccc ggctgcgt
//
