LOCUS       NZ_CP034587            22598 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2549522
            Orig. end                         :: 2572120
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="18"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12598)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(23..922)
                     /locus_tag="EKH77_RS10935"
                     /old_locus_tag="EKH77_10935"
     CDS             complement(23..922)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717857.1"
                     /locus_tag="EKH77_RS10935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10935"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_126914211.1"
                     /transl_table=11
                     /translation="MQLQQLRYFATVAEVRHFTRAAEALHVAQPSLSQQIRALERELGA
                     ELFHRARGNIALTDAGEALLPLARRILADTETAHREVQEVARLRRGRVRLGAPPSLCAS
                     LVPDVLRTYHARFPGIELHVDEGGSRDLVRRLADGGLDLALIITPLGVGAPALETTELL
                     REDLVVVSAPDGPAPTRRSRMRVGELRELPMVMFRSGYDLREITIAACRAEGFEPSFTV
                     EGGEMDAVLGFVRAGLGLAVVPGMVAARSGLRVTPFEGDRMRRTVAVAHRKDTPPPRAA
                     RELRRVLLDHLEAAPDED"
     misc_feature    complement(950..964)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            1010..1717
                     /locus_tag="EKH77_RS10940"
                     /old_locus_tag="EKH77_10940"
     CDS             1010..1717
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267828.1"
                     /locus_tag="EKH77_RS10940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10940"
                     /product="succinate dehydrogenase cytochrome b subunit"
                     /protein_id="WP_126914212.1"
                     /transl_table=11
                     /translation="MALATRAAKPPSLIGSVWRSTVGKKAVMAVTGLIMLAYLVAHMLG
                     NLKVFFGAGEFNHYAAWIRTIGEPFLHHEWFLWLARVTLSAAVVLHGVAAYQLSRRDLA
                     ARPVKYRGRGRGRASYATRTMRWGGVILGLFIVWHILDLTTLTVNPNAQEGRTYENLVA
                     SFDRWYVSAFYIAAMLALGLHIRHGFWSAAQTLGVGSPRRDRLLKALANGLAALLTCGF
                     IVVPVGVLTGVVS"
     misc_feature    complement(1731..1745)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            1737..3683
                     /locus_tag="EKH77_RS10945"
                     /old_locus_tag="EKH77_10945"
     CDS             1737..3683
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521353.1"
                     /locus_tag="EKH77_RS10945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10945"
                     /product="fumarate reductase/succinate dehydrogenase
                     flavoprotein subunit"
                     /protein_id="WP_126918003.1"
                     /transl_table=11
                     /translation="MTDYLDYAVGAPVADAAAPDGPIAERWDRRRFTAKLVNPANRRKL
                     TVIVVGTGLAGGAAGATLAEQGYRVTQFCYQDSPRRAHSIAAQGGINAAKNYRNDGDSI
                     HRLFYDTVKGGDFRARESNVHRLAQVSVEIIDQCVAQGVPFAREYGGLLDTRSFGGVQV
                     SRTFYARGQTGQQLLLGAYQALSRQIAADNVEMHARTEMLDLIVVDGRARGIVARDLIT
                     GRISTHFADAVVLASGGYGNVFHLSTNAKNSNATAVWRAHRRGAHFANPCFTQIHPTCV
                     PRSGDHQSKLTLMSESLRNDGRIWVPKAKGDTRAPGDIPESERDYYLERIYPSFGNLVP
                     RDIASRAAKNVCDEGRGVGPGGQGVYLDFADAIARMGRAAVETKYGNLFEMYERITAEN
                     PYEVPMRIYPAIHYTMGGLWVDYDLQTTVPGLFAIGEANFSDHGANRLGASALMQGLAD
                     GYFVLPSTINDYLARHPHDAIPPDHPAVVEAVDGVSARLRRLLAGDGDRTPESFHRELG
                     ELLWDECGMARTDSGLRKALDRIPALREEFWRRIKVPGTGEELNQSLEKANRIVDYLEL
                     AELMCLDALHRTESCGGHFREESRTADGEAARDDEAFSYVAAWEFTGTGKSPVLHKERL
                     IFAYVQPTQRSYA"
     gene            3930..5381
                     /gene="iscB"
                     /locus_tag="EKH77_RS10950"
                     /old_locus_tag="EKH77_10950"
     CDS             3930..5381
                     /codon_start=1
                     /gene="iscB"
                     /inference="COORDINATES: protein motif:HMM:NF040563.1"
                     /locus_tag="EKH77_RS10950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10950"
                     /product="RNA-guided endonuclease IscB"
                     /protein_id="WP_126918004.1"
                     /transl_table=11
                     /translation="MRGETLSGALTTGRVTPDRPVREAGRKAQPAVFVLDKHGAPLQPT
                     TPARARKLLKQGRAAVHRHTPFVIRMKDRTVTQSSVHGVELGIDPGSQYTGFAVFATTR
                     TEAGATRRGLYAIELAHRGNQIRDKLARRAAYRRGRRTRNLRYRTPRFLNRRRPKGWLA
                     PSLKHRLDTVLSWANRLARWAPISKVHIENTSFDTHALSVGRPLESTDYQKGSLYYCEA
                     REYLSVKWGRACAYCGVRAVRLNIDHIHPRSRGGADRVSNLVLCCVPCNQAKSNRPVEE
                     FLAHNPPALRRVLSQVKAPLRDAAAVNATRWAIQQTLATAFPVVCSASGGRTKWNRQRL
                     GLPKTHTLDALCVGSLDELSQYPAVFLSVTATGRGTYARTSADKYGFPRLYRPRTKLVH
                     GYATGDLAQAVVPSGKKAGTHVGRISVRTRGNFNIRTSQGLLQGIRHTYFHLLQRADGY
                     GYTARPEGAPSSPPEAARTDQRRLR"
     gene            5378..6133
                     /locus_tag="EKH77_RS10955"
                     /old_locus_tag="EKH77_10955"
     CDS             5378..6133
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003984411.1"
                     /locus_tag="EKH77_RS10955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10955"
                     /product="succinate dehydrogenase/fumarate reductase
                     iron-sulfur subunit"
                     /protein_id="WP_126914213.1"
                     /transl_table=11
                     /translation="MNLTLCIWRQRSPEDAGGMTTYEVSGISEDMSFLEMLDHLNEELI
                     LAGDEPVAFDHDCREGICGACGMVINGRAHGPERTTTCQLHMRHFSDGDTIDIEPWRAA
                     AFPVVKDLVVDRSAFDRVIGAGGYVSVPTGSAPEAHATPVPKPVADLAFEHAECIGCGA
                     CVAACPNGSAMLFTSAKVVHLNVLPQGAPERESRVLDMVGAMDDQGFGGCTNTGECATA
                     CPKGIPLQSIATMNREYLRATLKGAGRRR"
     gene            complement(6168..6476)
                     /locus_tag="EKH77_RS10960"
                     /old_locus_tag="EKH77_10960"
     CDS             complement(6168..6476)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451031.1"
                     /locus_tag="EKH77_RS10960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10960"
                     /product="transcriptional regulator"
                     /protein_id="WP_126914214.1"
                     /transl_table=11
                     /translation="MTDPEDGFNETIHAPNRLRICAALDAVEEIEFATVRETLGVSPSV
                     LSKHVTVLTDAGYVEQRRAVRDTRQRVWLRLTKDGRDAYRAHLAALRAIVNADLGEG"
     gene            complement(6473..6937)
                     /locus_tag="EKH77_RS10965"
                     /old_locus_tag="EKH77_10965"
     CDS             complement(6473..6937)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS10965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_10965"
                     /product="hypothetical protein"
                     /protein_id="WP_126914215.1"
                     /transl_table=11
                     /translation="MATDENSRSSRPSMPSREGAAEALALAEQAQVAVASLTPGRAFDV
                     KLSLCVAGVYLSHLLPEPWDFVGLALMYVIMLAVLALHFRSSGVRHRVNPGMKRSMFGA
                     AVLAFGLYMVALYLDDHQGMPWIWVPAGLLAAGGILALDSKTRKKGIAAS"
     gene            7090..7707
                     /locus_tag="EKH77_RS10970"
                     /old_locus_tag="EKH77_10970"
     CDS             7090..7707
                     /GO_function="GO:0022841 - potassium ion leak channel
                     activity [Evidence IEA]"
                     /GO_process="GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018446.4"
                     /locus_tag="EKH77_RS10970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10970"
                     /product="TMEM175 family protein"
                     /protein_id="WP_126914216.1"
                     /transl_table=11
                     /translation="MARDPYVIEMDRMLAFADAVTAIAITLLALEIHVPEGLPDAEVGQ
                     AFGHLLPKVLAYLVGFVLVGAIWLGHHKLFRLMATLDRAMVRLEFALLAVIAFLPFTAR
                     LMSEHGGAPVAMAVYTGAIGLEAALLAVMALRLRAPGPLRRPEVTRQQVAREVFDNASI
                     ATIALVALLIALAAPLVAVWWWVLIWPVRGLPRYWPWLRARL"
     gene            complement(7776..8036)
                     /locus_tag="EKH77_RS10975"
                     /old_locus_tag="EKH77_10975"
     CDS             complement(7776..8036)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139226.1"
                     /locus_tag="EKH77_RS10975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10975"
                     /product="Prokaryotic metallothionein"
                     /protein_id="WP_126914217.1"
                     /transl_table=11
                     /translation="MAQCNTCGNDYWLAFEVKTITGDTYTFDSFECAINKLAPRCEHCE
                     SRIIGHGVEVAGRFFCGAHCAREGDSGLGSQIRDTVGAHPG"
     gene            complement(8184..9995)
                     /locus_tag="EKH77_RS10980"
                     /old_locus_tag="EKH77_10980"
     CDS             complement(8184..9995)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885658.1"
                     /locus_tag="EKH77_RS10980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10980"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_126914218.1"
                     /transl_table=11
                     /translation="METVNAAAEARETGRGTGDAERAARPRGAGRRALARYLRPQRPAI
                     LGGALLGLAGGALGLAQPLAAERLVNDLERDRTATTEVIALGVLVLLGAVLVALGHLVL
                     ERAAERLVCTARRGLADRLLRLRVPVAERHEPGDLISRVTADTTLLRQVATQAMAAALT
                     GTVITLVTVVMMGVLDLVLLGVTLAVIAFISLSSGLVIPRIGRATRQTQEAVGGMGAAL
                     ERAFGAFRTVKASGAEQCEIARLHEAAERARRMGTRAASWEAVSDTVSQVSVQVSFLVV
                     LGVGGVRVASGAIDVSTLVAFLLYLFSLAPRINQLVGAAGQFQVGAAAALRIREAEEMA
                     VEDPGAGPEPAADAGCGPRPASVAFDRVRFGYRPGLPAVHRRISFTVPARGLTAFVGPS
                     GAGKTTVFSLIERFYEPDSGRVLLDGRDVRHWPLSALRAAIGYVEQDAPVLAGTLRENL
                     LLGVPHATDGQLREVLRRARLDDLADRLPEGLDTTVGHRGSMLSGGERQRVAIARALLR
                     SPRLLLLDEATSQLDAANEAALRGTVADAARTMTVLVVAHRLSTVTGADRIVVMEAGRI
                     RAVGTHAKLLASDELYGRLAATQLLAN"
     gene            complement(10001..10417)
                     /locus_tag="EKH77_RS10985"
                     /old_locus_tag="EKH77_10985"
     CDS             complement(10001..10417)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047207.1"
                     /locus_tag="EKH77_RS10985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10985"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_126914219.1"
                     /sec_met_domain="PF13471 (E-value: 3e-24, bitscore: 83.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPEAVPYRPGAVPLATRWAARAAVALAHLLATQPPGRIRAVLR
                     VLRRGARPASLAEATGARDAVLAVSLASGGQKGCLPRSLATVLLCRMRGQWAVWCVGVR
                     SRPPFAAHAWVEAESVLVGEGAPADYFQRFFTVE"
     gene            complement(10414..10680)
                     /locus_tag="EKH77_RS10990"
                     /old_locus_tag="EKH77_10990"
     CDS             complement(10414..10680)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175266.1"
                     /locus_tag="EKH77_RS10990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10990"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_126914220.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.5e-22,
                     bitscore: 78.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.4e-15, bitscore: 53.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRLRSGVVMTETDYGIALLDQTTGEYWTLNPTAALVLRTLLDG
                     ESRGQAAHALAARYDVDPGEAARDVERVYGELRSARLLSGTRP"
     aSDomain        complement(10432..10680)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EKH77_RS10990_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.30E-25"
                     /identifier="RREFam002.1"
                     /label="EKH77_RS10990"
                     /locus_tag="EKH77_RS10990"
                     /protein_end="83"
                     /protein_start="0"
                     /score="78.0"
                     /tool="antismash"
                     /translation="MSLRLRSGVVMTETDYGIALLDQTTGEYWTLNPTAALVLRTLLDG
                     ESRGQAAHALAARYDVDPGEAARDVERVYGELRSARLL"
     gene            complement(10757..12598)
                     /locus_tag="EKH77_RS10995"
                     /old_locus_tag="EKH77_10995"
     CDS             complement(10757..12598)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986679.1"
                     /locus_tag="EKH77_RS10995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_10995"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_126914221.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.8e-33, bitscore:
                     114.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRSSSLSALPTWFLVLPDTAAEAVTEIAARARPHAVQSVPHPSG
                     RPWLLGRWDPEAFTLGEAGDARVAVLGEHAVSGAEAARAAGAVRTAGTLDALGRFAAAW
                     PGSFHLLARDAGGRVRIRGGVVGVRRVFHARTGPDAVAADRADVLADLLDAGLDEDRLA
                     VQLLAMGLLYPLNSRPVWHGVEALPGDHHLTLGPEGPARIGRWWTPPEPDVPLGEGAAR
                     LAAALGAAVDVRTRGRSLVTCDLGGLDSTAVCCLAARGDAKIVAYTAALRDPLGDDTHW
                     ARRTVDALGTVEHHEIPAGEVPLTFDGLGTFDQLLDAPSLMTVDHSRRMSIVRLAAERG
                     SALHLTGIGGDEVLSGASARLHALARTHPRVALRHLRGYRAKYRWPRGLVLRQLLDRRS
                     YRSWLTRVAADLTEPPAPSNAPVLDWSERPRMPHWATPDAVASVRRQILAAARTAAPLA
                     RDHGAHRELATMECISRFARHVGQLAGPLGVVCSAPYYDDRVVEAGLSVRPQERITPWR
                     YKPLIVEATRGVVPEVSRTRATKANASLEEETGLREHRARLLDLCEDSRLARLGLIDAG
                     ALRDWCLRPLEVEVESSLLHTTVACEVWLRSRESMSR"
     misc_feature    complement(12739..12754)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.09"
                     /tool="antismash"
     misc_feature    complement(12754..12763)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.42"
                     /tool="antismash"
     gene            complement(12781..12888)
                     /locus_tag="EKH77_RS11000"
                     /old_locus_tag="EKH77_11000"
     CDS             complement(12781..12888)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039305.3"
                     /locus_tag="EKH77_RS11000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11000"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_126914222.1"
                     /transl_table=11
                     /translation="MTYERPTIAKAGGFRKVTGLASKTAKDVLGGHNLV"
     misc_feature    complement(13180..13193)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.24"
                     /tool="antismash"
     gene            complement(13223..14929)
                     /locus_tag="EKH77_RS11005"
                     /old_locus_tag="EKH77_11005"
     CDS             complement(13223..14929)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018570065.1"
                     /locus_tag="EKH77_RS11005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11005"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_126914223.1"
                     /transl_table=11
                     /translation="MKSVSVAVIEAARAGDTAAQDELVATHLPLVYNIVGRALNGHADV
                     DDVVQETMLRVINGLDGLRDAASFRSWLVAITMNQIRSHCREERPEAPVSGLQEVVGEV
                     PDPKADFVDLTIVRLGLEGQRKEAAEATRWLDEGEQEVLSLWWLEAAGELKRAEVVAAL
                     GLTPQHTAVRIQRTKAQLDVARGVVQALAAYPRCERLGEVVATWDGVPSALWRKRVARH
                     VRACGRCTGALSTLVPAEGLLVGLGLVPVGGALLGWWGGGAVVPGEPVGFASAAHPAAA
                     PTAPHGGRAAARRAGGQRGGGHRSAGRSGGHRAGGGRSRTGRNAVMGAGALALIAGGVL
                     GGGYLMEDSPATTVKTQAVDASGDLKQLNAREPMPIKPTPSLSASPSASASASASASAS
                     PSGSASPSPSAKSSASHADESAPERTAAPARTRAPKPPSSGGDGSMAAQVVALVNAERA
                     KVGCSALTSNSLLDAAAQGHSDDMAARNFFNHTNPDGKGPGDRITAAGYNWSTYGENIA
                     YGQQDAASVMDSWMHSDGHRKNILNCSFKEIGVGINKAPGGPRWTQVFGAR"
     misc_feature    complement(15005..15014)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.37"
                     /tool="antismash"
     gene            complement(15042..16592)
                     /locus_tag="EKH77_RS11010"
                     /old_locus_tag="EKH77_11010"
     CDS             complement(15042..16592)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015648.4"
                     /locus_tag="EKH77_RS11010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11010"
                     /product="PH domain-containing protein"
                     /protein_id="WP_126914224.1"
                     /transl_table=11
                     /translation="MVRLRAPRHPVDPRARAWWTARALLTVSGPAALAAATLLTLCFLF
                     FPGAASWLVPLVTAVLVAPAVAYAVVMPARRCRTHGWELGESALYAVSGWYGRRRRIVP
                     LDRVESVALRRGPLLRRYGLAVVVVGMGPDAEAVRITGVSEPEARRLRAGIEGAVAASA
                     AETAASRTEGGRGAGILAVGRAGWLRYAPLTFWVWGGVLVAGGTTWRVLNAFGVKPWRI
                     GIVRRLWAGYGAGAPWLAALLGLAAVTLLGVAGALAVHAATWWRYRLERTPSGGLDVRR
                     GLFATSVVSIDADRLCGVALREPLLLRAGGGASVRAVAGGLGDRERNRKRSVALPPAPR
                     AEALRVCAEVLGTDGVLEAGALRPAPRVALRRRLVWALGWGVLPVALVLVALGWLLELP
                     VLLWCAAGWVAVASPMVCALARDAYRALGYAVRGRHLVVRSGTFGRETVALERSSVQGW
                     TFTDTPFASRADVVTVTAIVAAGEGGYRIRDMSATEAVQFAEYAAPGIVREFLIQTSA"
     gene            16704..17300
                     /locus_tag="EKH77_RS11015"
                     /old_locus_tag="EKH77_11015"
     CDS             16704..17300
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179604.1"
                     /locus_tag="EKH77_RS11015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11015"
                     /product="TetR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_126914225.1"
                     /transl_table=11
                     /translation="MPKRVDHDERRHRIAEALWRIASERGLDGASLRDVAAEAGISLGQ
                     LQHYFRTKDDMLVFALGHISELAARRIGARVGSLAGDPSPRTLLRETLAEMLPLDDKSR
                     TGQLVQIAYFVRAVHDERLRRHAKEGIPALREFFAAQIRRAMEGGDIAADRDPDTEAML
                     LISLVDGLTGYVLLDVLPGEEAMRLVDAHLDRLFT"
     gene            complement(17321..19411)
                     /locus_tag="EKH77_RS11020"
                     /old_locus_tag="EKH77_11020"
     CDS             complement(17321..19411)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942984.1"
                     /locus_tag="EKH77_RS11020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11020"
                     /product="FUSC family protein"
                     /protein_id="WP_126914226.1"
                     /transl_table=11
                     /translation="MTWASALKKTARAGLTIERVTLEPLVAVRGACGVAVVVGLMLAFG
                     SPALAVSSAFGAFASGLATFQRSWRPRPLLALAVAGVLGLSTFLGYLAAAHLALFVALL
                     AVWTLLSGMAWAVGPVTGFVATQTIAVMLVTVTLPTSVAGAAEHAALILVGGLVQAALI
                     VVFPIRPWGRQRDALADALAAEADYARRLRHDPVAHFDPQPLMHARSAAELTPRQARSR
                     PRQLGGARGVAERIRPVLASLADPVVGAPPEGPGRDRARELLGAAADVLDAVARAIRRG
                     RPVRVTPEVMATLEVPESGPRLDGAARRSALRLMALLADVVEAGDEPLRATRPTAGAER
                     RHLLRPTVAGLVPVAWRALRREARWSSPVGRHAVRVTTVACAGYLLGTVLPLGHGYWVP
                     MTSVMVMRPDFAQTYQRGVARFVGTLVGVWAGAGIMALTHPGPPVCAALAVVSVGLLYL
                     LMRTGYIVVSACIGAYIVFLLGIAGEGWSQTVQARLALTLLGGVLALAAYALWPTWETP
                     RLRDRLADWLRTNGDYALAVLDAHARPENRKRRVREALLDARAARLEWEEAAARAQQEP
                     VRHRGISRAAERSAESALATLGRAAMLMEAHLPGPDAEPDPGADEFAAALRAALPDAVT
                     AVRERRRPDWSGPHVALAAWVARVGDEGVAVRGSELMVEALDELAEALAPGQRGRNRAA
                     RR"
     gene            complement(19522..21024)
                     /locus_tag="EKH77_RS11025"
                     /old_locus_tag="EKH77_11025"
     CDS             complement(19522..21024)
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007826817.1"
                     /locus_tag="EKH77_RS11025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_11025"
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_126914227.1"
                     /sec_met_domain="Aldedh (E-value: 1.4e-136, bitscore:
                     454.3, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTVNHWIDGKSVEGTSGTYGPVTDPATGVVTTRVAFATAEEVDA
                     AVAAAKAAYGTWGGSSLAQRTAVLFRYRALLDAHREELARLITAEHGKVHSDALGEVAR
                     GLEVVELACGITQQLKGELSTQVSSRVDVSAIRQPLGVVAGITPFNFPAMVPMWMFPLA
                     IACGNTFVLKPSEKDPSSAIRLAELAAEAGLPDGVLNVVNGDRVAVDRLLEHPDVAAVS
                     FVGSTPIARYIHTTASANGKRVQALGGAKNHMLVLPDADLDAAADAAVSAAYGSAGERC
                     MAISAVVAVGGTGDELVAKIRERAEKIKIGPGDDPASEMGPLITKDHRDKVAAYVAGAA
                     AQGAEVVLDGTGFSGPGSVEYAAGHWIGLSLLDKVPTDADAYRDEIFGPVLCVLRAETY
                     EEGLAIVNASPWGNGTAIFTRDGGMARRFQLEVEAGMVGVNVPIPVPVGYHSFGGWKHS
                     LFGDHHIYGNDGVRFYTRGKVVTTRWPDPADGGVDLGFPHHG"
     misc_feature    21317..21332
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.01"
                     /tool="antismash"
     misc_feature    complement(21650..21664)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.33"
                     /tool="antismash"
     misc_feature    22473..22487
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.29"
                     /tool="antismash"
ORIGIN
        1 ggccctcagt cctcgtccgg cctcagtcct cgtccggcgc ggcttccagg tggtccagca
       61 gcacccgccg cagttcgcgg gccgcacgcg gcggcggggt gtccttgcgg tgggcgacgg
      121 cgacggtccg ccgcatgcgg tcgccctcga agggggtgac ccgcaggccg gagcgggcgg
      181 cgaccatgcc ggggacgacg gccaggccca gcccggcccg gacgaagccc aggacggcgt
      241 ccatctcgcc gccctcgacg gtgaaggagg gctcgaagcc ctcggcccgg caggcggcga
      301 tggtgatctc gcgcaggtcg tagccgctgc ggaacatcac catcggcaac tcccgcagct
      361 cgcccacccg catccggctc cggcgcgtgg gcgcgggccc gtccggtgcg gacaccacca
      421 ccaggtcctc ccgcagcagc tccgtcgtct ccagcgcggg ggcgcccacg ccgagggggg
      481 tgatgatcag ggccaggtcg agcccgccgt cggccagccg gcgcaccaga tcccgtgagc
      541 cgccctcgtc gacgtgcagt tcgatgccgg ggaagcgggc gtggtacgtg cgcagcacgt
      601 ccggcaccag gctcgcgcag aggctcggcg gggcgccgag ccggacccgg ccgcgccgca
      661 gccgggccac ttcctgcacc tcgcggtggg cggtctcggt gtcggcgagg atgcggcggg
      721 cgagcggcag gagggcctcg ccggcgtcgg tcagggcgat gttgccccgc gcgcggtgga
      781 agagctcggc gcccagctcc cgttccagcg ccctgatctg ctgggacagc gagggctggg
      841 cgacgtggag ggcctcggcg gcccgggtga agtgccggac ctcggcgact gtggcgaagt
      901 agcggagctg ctgaagttgc accccaccag ggtagatagg gaaagcctat ggaaacgagc
      961 cccatcatgt cttggacgca tcgaagtccg ccgacctagc gtcggcggca tggcactggc
     1021 gacccgggcg gcgaaacctc cgtccctcat cggctccgtg tggcgctcga ccgtcggcaa
     1081 gaaggcggtc atggcggtca ccggcttgat catgctggcg tatctggtcg cccatatgct
     1141 gggcaatctc aaggtcttct tcggggccgg ggagttcaac cactacgcgg cctggatccg
     1201 caccatcggc gaaccgttcc tccaccacga gtggttcctg tggctggccc gggtgacgct
     1261 gagcgccgcg gtcgtcctcc acggtgtggc cgcgtatcag ctcagccgcc gggacctcgc
     1321 ggcccgccca gtgaagtacc ggggccgcgg gcgggggcgc gcgagctacg cgacccgcac
     1381 catgcgctgg ggcggggtga tcctcggcct gttcatcgtc tggcacatcc tcgacctcac
     1441 caccctcacc gtgaacccca acgcccagga ggggcggacg tacgagaacc tcgtcgcctc
     1501 cttcgaccgg tggtacgtct ccgccttcta catcgccgcg atgctggccc tcggcctgca
     1561 catccggcac ggcttctgga gcgcggccca gacgctgggc gtgggctcgc cccgccgcga
     1621 ccggctcctc aaggccctcg ccaatggcct ggccgccctg ctgacctgcg gattcatcgt
     1681 cgtgcccgtc ggtgtcctga caggagtcgt gagctgacat gagcgagatg agcgagatga
     1741 ctgattacct cgactacgcc gtcggcgctc cggtggccga cgcggcggcc ccggacgggc
     1801 ccatagccga gcgctgggac cgccgccgct tcacggcgaa gctggtcaac ccggccaacc
     1861 gccgcaagct caccgtcatc gtcgtcggca ccggcctggc gggcggcgcg gcgggcgcca
     1921 ccctcgccga acagggctac cgcgtgacgc agttctgcta ccaggactcc ccgcgccgcg
     1981 cccactccat cgccgcccag ggcggcatca acgccgccaa gaactaccgc aacgacggcg
     2041 actccatcca ccgcctcttc tacgacaccg tcaagggcgg cgacttccgc gcccgcgagt
     2101 ccaacgtcca ccggctcgcc caggtctccg tcgagatcat cgaccagtgc gtggcgcagg
     2161 gcgtcccctt cgcccgtgag tacgggggcc tgctggacac ccgctccttc ggcggcgtcc
     2221 aggtctcccg caccttctac gcccgcggcc agacgggcca gcagcttctc ctcggcgcgt
     2281 accaggcgct gagccgccag atcgctgcgg acaacgtcga gatgcacgcc cgtaccgaga
     2341 tgctcgacct gatcgtcgtc gacggccggg ctcgcggcat cgtcgcccgg gacctgatca
     2401 ccggccggat cagcacccac ttcgccgacg ccgtggtcct cgccagcggc ggctacggca
     2461 atgtcttcca cctctccacc aacgccaaga actccaacgc caccgccgtc tggcgggccc
     2521 accggcgcgg cgcccacttc gccaacccct gcttcaccca gatccatccg acctgcgtcc
     2581 cgcgctccgg cgaccaccag tcgaagctga cgctgatgag cgagtcgctg cgcaacgacg
     2641 gccgcatctg ggtgcccaag gcgaagggcg acacgagggc gcccggggac atccccgaat
     2701 ccgagcgcga ctactacctg gaacggatct atccctcctt cggcaatctc gtcccccgcg
     2761 acatcgcctc ccgcgccgcg aagaacgtct gcgacgaggg tcgcggagtc ggcccgggcg
     2821 gccagggcgt ctacctcgac ttcgcggacg ccatcgcgcg gatgggccgc gcggccgtcg
     2881 agacgaagta cggcaacctc ttcgagatgt acgagcggat cacggcggag aacccctacg
     2941 aggtccccat gcggatctac ccggccatcc actacacgat gggcggactg tgggtggact
     3001 acgacctcca gacgaccgtg cccggcctct tcgccatcgg cgaggccaac ttctccgacc
     3061 acggcgccaa ccggctgggc gcctccgccc tgatgcaggg cctagccgac ggctatttcg
     3121 tcctcccttc caccatcaac gactatctgg cccgccaccc ccacgacgcg ataccgccgg
     3181 accacccggc ggtcgtggag gccgtcgacg gcgtgagcgc ccggctgcgc cggctgctcg
     3241 cgggcgacgg cgaccgcacg cccgagtcct tccaccgcga gctgggcgaa ctgctgtggg
     3301 acgagtgcgg catggcccgc accgacagcg gactgcgcaa ggccctggac cgcatcccgg
     3361 cgctccgcga ggagttctgg cggcggatca aggtgccggg gacgggcgag gagctcaacc
     3421 agtcgctgga gaaggccaac cggatcgtcg actatctgga gctcgccgag ctgatgtgcc
     3481 tcgacgccct ccaccgcacg gagtcctgcg gcggccactt ccgggaggag agccggacgg
     3541 ccgacggcga ggcggcccgc gacgacgagg cgttctccta cgtcgcggcc tgggagttca
     3601 cggggacagg caaatcacct gttctccata aagagcgcct gatattcgcg tatgttcagc
     3661 ctacccagcg gagttacgcg taacgggttc tcccgccctc agggcggggg cctcggcctg
     3721 cgccgaggcc cgccgttacc agcaccagcc atcaccagca gggaggtgac ctcgatggct
     3781 acgttccacg caggacagag gaccgaccga gctgtgcttc ctcagcagcc cgctctcgaa
     3841 ttcgcgtcag cagacacccc gagaacaggg acgaaacggg tcgcgaacgc ctcacgacac
     3901 gacgtcgcgc ggcatccggc gtggaacatg tgcgagggga gacgctcagt ggcgcactta
     3961 ccaccgggcg cgtcaccccg gaccgtccgg tccgggaggc gggccgtaag gcccaaccgg
     4021 ccgtattcgt cctcgacaaa cacggcgcac cattgcaacc caccactcct gccagggccc
     4081 gtaagctcct caaacaggga cgggctgcgg tacaccgaca tacgccattc gtcatccgca
     4141 tgaaagaccg taccgtcact cagtcttcgg tgcatggtgt cgagttggga atcgaccccg
     4201 gctcccaata cacaggattc gctgtcttcg ccaccacacg cacggaggca ggggccactc
     4261 gccgtggcct atatgcgatc gaacttgctc accgcggaaa ccagatccgt gacaagctgg
     4321 cccgacgcgc ggcttaccga cgcggccgtc gcactcgaaa cctacgctac cgcacgcctc
     4381 ggttcctgaa ccgccgacgc ccgaaaggct ggctggcacc gtcactcaag caccgcttgg
     4441 acaccgtcct ctcctgggcg aaccgacttg cccgctgggc tccgatatcc aaagtgcata
     4501 tcgagaacac ctcattcgac acccatgctc tcagcgtggg aaggccactg gaatcaactg
     4561 attaccagaa aggcagtctt tactactgcg aggctcgcga gtatctctca gtaaagtggg
     4621 gtcgagcctg cgcttactgc ggcgttcgtg ccgtgcgact gaatatcgat cacatccacc
     4681 cacgatcaag gggtggggcc gatcgcgttt ccaacctcgt cctttgctgc gtcccctgca
     4741 atcaggccaa gagcaatcgc cccgtggagg agttcctggc gcataacccc ccagcattgc
     4801 gccgggtgct ttcccaggtc aaggccccgc tccgggacgc cgctgccgtc aatgccaccc
     4861 gctgggcgat acaacaaaca ctcgccacag catttcccgt cgtgtgcagt gcttctggtg
     4921 gtcgcaccaa gtggaaccgg caacgcctcg gccttccgaa gactcacacc ctcgatgcct
     4981 tgtgcgttgg ctcgctggac gagctgagtc aatacccggc cgtcttcctg tccgtcacag
     5041 caaccgggcg tggaacctac gcacgcacca gtgccgacaa gtacggcttc ccccgcctgt
     5101 accgtccgcg gaccaaactc gttcacggtt acgcgaccgg ggacctggcc caagcggtgg
     5161 ttccttccgg caagaaagcc ggcacacacg tcggccgcat ctcagtgcgc acccgaggca
     5221 acttcaacat ccgcacctct caaggtctcc ttcaagggat ccgacacacg tacttccacc
     5281 tgctacagcg agctgacgga tacggctaca cggcccgccc ggagggagca ccgtcctctc
     5341 cgcctgaggc cgcgaggacc gaccaaagga gactccgatg aacctcaccc tgtgcatctg
     5401 gcgccagcgc tcccccgagg acgccggggg catgaccacc tacgaggtca gtggcatcag
     5461 cgaggacatg tccttcctgg agatgctcga ccacctcaac gaggagctga tcctcgccgg
     5521 cgacgagccc gtggccttcg accacgactg ccgcgagggc atctgcggcg cctgtggcat
     5581 ggtcatcaac ggccgggccc acggcccgga gcgcaccacc acctgtcagc tccatatgcg
     5641 gcacttctcc gacggcgaca ccatcgacat cgagccctgg cgggccgccg ccttccccgt
     5701 cgtcaaggac ctggtcgtcg accgctcggc cttcgaccgg gtgatcggcg ccggcggcta
     5761 tgtctccgtg cccaccggct ccgcgcccga ggcccacgcc acacccgtac cgaagccggt
     5821 ggccgacctg gccttcgaac atgccgagtg catcggctgc ggcgcctgtg tggccgcctg
     5881 ccccaacggc tcggcgatgc tcttcacgtc cgcgaaggtg gtccacctga acgtcctgcc
     5941 gcagggcgcg ccggagcgcg agtcccgggt gctggacatg gtgggcgcca tggacgacca
     6001 gggcttcggc ggctgcacga acaccggcga gtgcgccacg gcctgcccca agggcatccc
     6061 cctccagtcg atcgcgacga tgaaccgcga gtacctgcgg gccaccctca agggcgccgg
     6121 acgacgccgc tgagccggcc cccaccgaca ccggcgcagg cgccgggtca cccctccccc
     6181 aggtcggcgt tgacgatcgc ccggagggcg gcgaggtggg cgcggtaggc gtcgcggccg
     6241 tccttggtca ggcgcagcca gacgcgctgc cgggtgtcgc gcacggcccg ccgctgctcg
     6301 acgtaccccg cgtcggtcag caccgtcaca tgcttgctga gcacggacgg gctcacgccc
     6361 agcgtctcgc ggacggtcgc gaactcgatc tcctcgacgg cgtcgagcgc ggcacagatc
     6421 cggagccggt tcggcgcatg gatcgtctcg ttgaagccgt cttcggggtc ggtcacgacg
     6481 ctgctatgcc cttcttacgg gttttgctgt ccagggccag gatgccccct gcggccagca
     6541 gacccgccgg gacccatatc cacggcatgc cctggtgatc gtccagatac agcgccacca
     6601 tatagagccc gaaggcgagg acggcggcac cgaacatgct ccgcttcatg cccgggttca
     6661 ctcggtgccg gacgccgctg gagcggaagt gcagcgccag gacggccagc atgatcacgt
     6721 acatcagggc gaggcccacg aagtcccatg gctcgggcag gagatgggac agatacaccc
     6781 cggccacaca cagggagagt ttcacatcga acgcccggcc gggggtgagg gacgcgaccg
     6841 ccacctgcgc ctgctccgcc agggccaggg cctcggcggc gccttcccgg gacggcatgg
     6901 acggccggga cgaccgcgag ttctcgtcag ttgccatgtc ggaaagtcaa gcacacggtt
     6961 tccgggtcgg caactctcga ctttccgctg tggaaaaccc ggattccggg cgccgccgaa
     7021 tcatccgatc gtgcggtttt ccgccgatac ccccgtaaag ttccccgcat ccgccctacg
     7081 ctggcgaccg tggcgcgcga cccgtacgtc atcgagatgg accgcatgct cgccttcgcc
     7141 gacgccgtga ccgccatcgc gatcacgctg ctggccctgg agatccacgt gccggaaggc
     7201 ctgcccgacg cggaggtggg ccaggcgttc ggccacctgc tgccgaaggt cctggcgtac
     7261 ctcgtcggct tcgtgctcgt cggggcgatc tggctcggtc accacaagct cttccggctg
     7321 atggccaccc tcgaccgggc catggtccgg ctggagttcg ccctgctggc cgtcatcgcc
     7381 ttcctgccct tcaccgcccg gctgatgagc gaacacggcg gcgcgcccgt ggccatggcc
     7441 gtctacacgg gcgccatcgg cctggaggcc gcgctgctgg ccgtcatggc gctgcggctg
     7501 cgcgcccccg gcccgctccg caggccggag gtcacccgtc agcaggtcgc ccgggaggtg
     7561 ttcgacaacg cgtcgatcgc caccatcgcc ctcgtcgccc tcctgatcgc cctggccgcc
     7621 cccctggtgg ccgtctggtg gtgggtgctg atctggccgg tgcgcggcct gccgcgctac
     7681 tggccgtggc tgcgcgccag actctgacgg gcccctcagc gcccccccgt cagcccccgc
     7741 cagcccctgc catcgcccca tcacccgtca ccccgtcacc ccgggtgcgc ccccaccgtg
     7801 tcgcggatct ggctccccag tcccgagtcg ccctcgcggg cgcagtgcgc cccgcagaag
     7861 aagcggcccg cgacctcgac gccgtggccg atgatgcggg actcgcagtg ctcgcacctg
     7921 ggcgcgagct tgttgatcgc gcactcgaag ctgtcgaagg tataggtgtc gccggtgatg
     7981 gtcttgacct cgaaggccag ccagtagtcg ttgccacatg tgttgcactg ggccatggcg
     8041 tgctccgtct cgatgcgggg gtacgggagg tacgcctcgc atgatctccg cgaggaccac
     8101 cccccaccgt caacacaaac aacccattca cccgaaggtg gtgccgcgtg cggctgtgtg
     8161 cacgccgccc gaccctcggc ccgtcagttc gccagcaact gcgtggccgc cagccgcccg
     8221 tacagctcgt cgctcgccag cagcttggca tgggtgccca cggcgcggat gcggcccgcc
     8281 tccatgacca cgatccggtc cgcgccggtc accgtggaca gccggtgggc gacgaccagc
     8341 accgtcatcg tccgggccgc gtcggcgacg gtgccccgca gggccgcctc gttggccgcg
     8401 tccagttgcg aggtggcctc gtccaggagc agcagccgcg ggctgcgcag caacgcgcgg
     8461 gcgatcgcga cacgttggcg ctcgccgccg gagagcatgc tgccccggtg gccgacggtc
     8521 gtgtcgagcc cttccggcag ccggtcggcc aggtcgtcga ggcgggcccg gcgcaggacc
     8581 tcccggagct gcccgtcggt ggcgtgcggg acgcccagga ggaggttctc ccgcagcgtt
     8641 ccggcgagga cgggcgcgtc ctgctcgacg tagccgatcg cggcgcgcag cgcggacagg
     8701 ggccagtggc ggacgtcccg gccgtccagc aggacgcggc cgctgtccgg ttcgtagaac
     8761 cgctcgatga gggagaagac ggtggtcttg cccgcgccgg acgggccgac gaaggcggtc
     8821 agcccccggg cgggcaccgt gaaggagatg cggcggtgca cggcgggcag cccgggccgg
     8881 tagccgaagc gcacccggtc gaaggcgacc gacgcggggc gggggccgca tccggcgtcc
     8941 gccgccggct ccggcccggc gccggggtcc tcgaccgcca tctcctcggc ctcccggatc
     9001 cgcagggcgg ccgccgcccc cacctggaac tggccggcgg cgcccacgag ctggttgatg
     9061 cggggggcga gcgagaagag gtagagcagg aaggcgacga gcgtggagac gtcgatcgcc
     9121 ccggaggcga cgcgcacgcc gcccacgccc agcaccacca ggaaggagac ctgcacggac
     9181 acctgggaga cggtgtccga gacggcctcc caggaggcgg cgcgcgttcc catgcggcgg
     9241 gcccgctcgg cggcctcgtg caggcgggcg atctcgcact gctcggcccc ggacgccttg
     9301 accgtgcgga aggcgccgaa ggcgcgttcc agggcggcgc ccatgccgcc gacggcctcc
     9361 tgggtctgcc gggtggcgcg gccgatgcgg gggatcacca ggccgctgct caggctgatg
     9421 aacgcgatca ccgcgagggt cacgccgagc agcaccaggt ccagcacccc catcatcacg
     9481 acggtgacga gggtgatgac ggtgccggtc agggccgcgg ccatcgcctg tgtggccacc
     9541 tgacgcagca gcgtcgtatc ggcggtgacc cgggatatca gatcgccggg ttcatggcgc
     9601 tcggctacgg ggacccgcag cctgagcagc cggtcggcga gcccgcgccg ggcggtgcac
     9661 acgagccgtt cggccgcccg ttccagcacg aggtggccga gggcgacgag caccgcgccc
     9721 agcaggacga gcacaccgag ggcgatcacc tccgtggtgg ccgtccggtc ccgttcgagg
     9781 tcgttcacca ggcgttcggc ggccagcggc tgggccaggc ccagggcgcc gccggcgagc
     9841 cccagcagcg cgccgccgag gatggcgggg cgctgcggcc ggaggtaccg ggccagggcc
     9901 cggcggcccg cgccccgcgg ccgcgccgcg cgctccgcgt ccccggtccc ccgcccggtc
     9961 tcccgcgctt ccgccgccgc gttcacggtc tccatgacac tcactccacg gtgaagaagc
    10021 gctggaagta gtcggccggt gcgccctcgc ccaccaggac cgactccgcc tccacccacg
    10081 cgtgtgccgc gaagggcggc cgggagcgga ctcccacgca ccacacggcc cactggccac
    10141 gcatccggca cagcagcacc gtggcgaggg accgtgggag acagcctttc tgccccccgc
    10201 tggcgaggct gacggcgagg acggcgtccc tggcgccggt cgcctcggcg aggctcgcgg
    10261 gccgggcccc gcgccggagc acgcgcagga ccgcgcggat gcgcccgggc ggctgggtgg
    10321 ccagcagatg ggcgagggct acggcggcgc gggcggccca gcgggtggcg agggggacgg
    10381 cgcccggccg gtacggaacc gcctccgggg tcgtcatggc cgggtcccgg acagcagcct
    10441 ggccgaccgc agttcgccgt agacgcgctc gacgtcgcgt gccgcctcgc cgggatccac
    10501 gtcgtagcgc gcggccagcg cgtgggcggc ctgccccctg gactccccgt cgaggagcgt
    10561 ccgcaggacg agcgcggcgg tggggttgag ggtccagtac tcgccagtgg tctgatccag
    10621 cagggcgatg ccgtagtcgg tctcggtcat caccactccg gagcggagtc ggagcgacat
    10681 tttccacctt tccggtcggt tccgttccag cggttcgcga cgtcagcggt ttcgcgatgc
    10741 cgcgcttctc gcgacgtcag cggctcatcg attcccggga gcgcagccac acctcgcagg
    10801 ccacggtggt gtgcaacagg ctgctctcga cctccacttc gagcgggcgc aggcaccagt
    10861 cccgcagcgc gcccgcgtcg atcaggccca gccgcgcgag gcgggagtcc tcgcacaggt
    10921 ccagcagccg ggcgcggtgc tcccgcaggc ccgtctcctc ctccagggag gcgttggcct
    10981 tggtggcccg ggtgcggctg acctcgggga cgacgccgcg ggtggcctcg acgatcagcg
    11041 gcttgtagcg ccagggggtg atccgctcct gcggccgtac cgacaggccc gcctcgacga
    11101 cgcggtcgtc gtagtacggg gccgagcaga cgacgcccag cgggccggcc aactgcccca
    11161 cgtgccgggc gaaccgggag atgcactcca tggtcgccag ctcgcggtgc gcgccgtggt
    11221 cccgggccag gggtgccgcg gtgcgggccg ccgcgaggat ctggcggcgt acggacgcga
    11281 ccgcgtccgg agtcgcccag tggggcatcc ggggccgctc ggaccagtcc agcaccggcg
    11341 cgttcgacgg cgcgggcggc tcggtgaggt ccgcggcgac ccgcgtcagc caggaccggt
    11401 aggaacggcg gtcgaggagc tggcggagca cgagcccccg gggccagcgg tacttggcgc
    11461 ggtaaccgcg caggtggcgc agcgcgacgc gcgggtgggt gcgggcgagg gcgtggaggc
    11521 gggcggaggc gccgctgagc acctcgtccc cgccgatgcc ggtgaggtgg agggccgagc
    11581 cgcgctcggc ggccagccgc acgatgctca tacggcggct gtggtcgacc gtcatgaggg
    11641 agggggcgtc gaggagctgg tcgaaggtgc cgaggccgtc gaaggtcagg ggcacctccc
    11701 cggccgggat ctcgtggtgc tcgacggtgc ccagggcgtc gacggtgcgg cgcgcccagt
    11761 gggtgtcgtc gccgaggggg tcgcggagtg cggccgtata ggcgacgatc ttggcgtcgc
    11821 cgcgtgcggc caggcagcag accgcggtgg agtccaggcc gccgaggtcg cacgtcacca
    11881 gggaacggcc gcgggtgcgg acgtcgacgg cggcgcccag cgccgccgcg aggcgcgcgg
    11941 cgccctcgcc cagcgggacg tccggctccg gcggtgtcca ccagcgcccg atgcgggcgg
    12001 ggccctcggg gccgagggtg aggtggtggt ccccgggcag ggcttcgact ccgtgccaga
    12061 ccggccggga gttcaggggg tacaggaggc ccatcgcgag caactggacg gccaggcggt
    12121 cctcgtcgag gccggcgtcg agcaggtcgg ccagcacgtc cgcgcggtcc gccgcgacgg
    12181 cgtccgggcc cgtacgggcg tggaagacgc gccgtacgcc gacgacgccg ccccggatcc
    12241 ggacgcgtcc gccggcgtcc cgggccagca ggtggaagct tcccggccag gcggcggcga
    12301 accggccgag cgcgtcgagg gtcccggccg tccggacggc cccggcggcc cgtgcggcct
    12361 cggcaccgga caccgcgtgc tcgcccagga ccgccacccg ggcgtccccg gcctcgccca
    12421 gggtgaacgc ttccgggtcc cagcggccca ggagccacgg ccggccggaa gggtggggca
    12481 cgctctggac cgcgtggggg cgggcccgcg cggcgatctc cgtgaccgcc tcggcggcgg
    12541 tgtcgggcag gacgaggaac caggtgggca gggcggacag ggacgaggaa cggtccatgc
    12601 gcaaacacct ccggccgtcg atccgggcgg cattctcggc atcgcttcgc ggaaaacgga
    12661 tggaaatcgg ggggtgaacg gcccatggcc ctcacccccc gattccgggg gcctcccgct
    12721 cgtcaccggt cattcttcag tggactcgac cagtgaaaaa acgggcccct tccggccgtc
    12781 tcagacgagg ttgtgaccgc cgagaacgtc cttcgcggtc ttgctggcca ggcccgtcac
    12841 cttgcggaag ccgccggcct tggcgatggt gggacgctcg tacgtcatgg cgttctcctt
    12901 cttcgcgatg cgaacgatga accgcaggtc acctgctcac ggccgggggg agcgccccct
    12961 cgcccccgcg cacaccactg ctcgtaaggg cagggggcga cgcctcccgg atctttcgat
    13021 cccggccgca cgaagagagt aaatatgacg aacacatcat cacaatgctc tggctctgcc
    13081 gttggtggtg aaatgcgggc gccctatcgc gacgcgcgcc cggggaactc ccgggcgcgc
    13141 tgcgacattt accgcgacgc gaaaatcagc ggtcagtcat cctcataatt caaccatcaa
    13201 catgtggtgg aacgagcgga attcaccgcg ccccgaacac ctgggtccag cgcggaccgc
    13261 ccggcgcctt gttgatgccg acgccgatct ccttgaagga gcagttgagg atgttcttgc
    13321 ggtggccgtc gctgtgcatc cacgagtcca tgaccgacgc cgcgtcctgc tgcccgtagg
    13381 cgatgttctc gccgtaggtg ctccagttgt agcccgccgc ggtgatgcgg tcgcccgggc
    13441 ccttgccgtc ggggttggtg tggttgaaga agttccgggc cgccatgtcg tcggagtgac
    13501 cctgggcggc cgcgtccagg aggctgttgg aggtcagggc cgagcagccc accttcgcgc
    13561 gctccgcgtt gaccagcgcc accacctgcg cggccatgga accgtcgccg ccggaggacg
    13621 gcggcttggg cgcccgggtg cgggccgggg cggccgtgcg ctcgggggcg gattcgtccg
    13681 cgtgggacgc cgaggacttc gccgacggcg aggggctcgc cgaaccgctc ggcgaggcgc
    13741 tcgccgaggc cgacgcggac gccgaggcgc tcggcgaggc ggagagcgac ggcgtgggct
    13801 tgatgggcat gggttcgcgg gcgttcagct gcttcaggtc gccggacgcg tccacggcct
    13861 gcgtcttgac ggtcgtggcg ggcgagtcct ccatgaggta gccgccgccc agcacgccgc
    13921 cggcgatcag ggcgagcgcg cccgcgccca tcacggcgtt gcggcccgta cgcgaccgcc
    13981 cgccgcccgc gcggtgcccg ccggaccggc cggcggaacg gtgcccgccg ccccgctgac
    14041 caccggcacg gcgggcagcc gcccggccac cgtgcggggc ggtcggcgcg gcggccgggt
    14101 gcgccgccga cgcgaagccc acgggctcgc ccggcaccac ggcaccgccg ccccaccagc
    14161 ccagcagcgc gccgccgacc ggcaccagac cgaggccgac cagcaggccc tcggccggga
    14221 ccagcgtcga cagggcgccc gtgcagcggc cgcaggcgcg cacgtgccgg gcgacgcgct
    14281 tgcgccacag cgcggacgga acgccgtccc acgtggcgac gacctcgccg agccgctcgc
    14341 agcgcgggta cgcggcgagc gcctggacga cgccgcgggc gacgtccagc tgcgccttcg
    14401 tccgctgtat tcggacggcg gtgtgctgcg gggtcagccc gagcgcggcg acgacctcgg
    14461 cgcgcttcag ctcgccggcg gcctccagcc accacaggga caggacctcc tgctccccct
    14521 cgtccagcca gcgcgtggcc tcggcggcct ccttgcgctg gccctccagg cccagccgga
    14581 cgatggtcag gtcgacgaag tcggccttcg ggtccggcac ttcgccgacc acttcctgca
    14641 gaccactgac gggagcctcg gggcgctcct cccggcagtg gctgcgtatc tggttcatgg
    14701 tgatggcgac gagccaggac cggaagctcg cggcgtcgcg cagcccgtcc aggccgttga
    14761 tcacgcggag catggtctcc tggaccacgt cgtcgacgtc cgcgtggccg ttcagggccc
    14821 ggccgacgat gttgtagacg agtggcaggt gggttgcgac gagctcgtcc tgtgccgccg
    14881 tgtccccggc acgcgccgcc tcgatcacgg ccacgctcac actcttcacg cccgcacctc
    14941 tttccgcacc cgccacgaat ggcgctcgat ccgacaccta ggagaccggg cgccgatcgg
    15001 cagataacaa aaaagttggg tgcgaatgta cgacaggtgg ttcaggcgga tgtctggatc
    15061 aagaactcac gaacgatccc cggagccgca tattccgcaa actggacggc ctccgtcgcc
    15121 gacatgtccc gtatgcggta tccgccctcc ccggcggcga cgatcgcagt gacagtgacc
    15181 acatccgccc ggctcgcaaa gggcgtatcg gtaaatgtcc atccctgtac ggaactccgc
    15241 tcgagggcca ccgtctcccg tccgaacgtc ccggaccgta cgaccagatg gcgcccccgc
    15301 accgcgtacc ccagcgcccg gtaggcgtcg cgcgccagcg cgcacaccat cggcgaggcc
    15361 accgccaccc accccgccgc gcaccacagc agcaccggca gctccagcag ccaccccagc
    15421 gcgacgagca ccaacgccac cggcaggacg ccccacccca gcgcccacac cagccgccgc
    15481 cgcaacgcga ccctcggggc gggacgcaga gcccccgcct cgagcacccc gtccgtcccg
    15541 agcacctctg cgcacacccg gagcgcctct gcccggggcg ccggagggag tgcgacgctc
    15601 cgcttgcggt tgcgctcccg gtcgcccagg ccgcccgcca cggcccgtac ggacgccccg
    15661 ccacccgcgc gcagcagcag cggttcccgc agcgcgaccc cgcacaaacg gtccgcgtcg
    15721 atggagacga ccgatgtcgc gaacagcccg cgccggacgt cgagaccgcc cgaaggcgtg
    15781 cgctccagcc ggtaccgcca ccaggtcgcg gcgtggaccg ccagcgcccc cgccacgccc
    15841 agcagggtca cggccgccag gccgagcagc gcggcgagcc acggcgcgcc ggcgccgtaa
    15901 ccggcccaca gacggcggac gatcccgatc cgccagggct tgacgccgaa ggcgttgagc
    15961 acgcgccagg tcgtgccgcc cgccacgagg acgcctcccc agacccagaa cgtcagcggg
    16021 gcgtaccgca gccagcccgc ccttccgaca gcgagaatcc cggcgccacg cccgccctcg
    16081 gtgcgggagg ccgctgtctc ggcggccgaa gcggccaccg ccccctcgat tccggcccgc
    16141 agccgccggg cctccggctc cgacaccccc gtgatccgta cggcctcggc gtccggcccc
    16201 atgccgacga ccaccacggc cagcccgtac cgccgcagca gcggcccgcg gcgcagtgcg
    16261 acggactcca cgcggtccag cggcacgatc cggcgccgcc gcccgtacca gccggagacc
    16321 gcgtagagcg ccgactcccc cagctcccac ccgtgcgtcc ggcaccgccg cgccggcatg
    16381 accaccgcgt acgccacggc gggtgccacg agcaccgccg tcaccagtgg caccagccat
    16441 gacgcggcgc cgggaaagaa gaggaagcag agggtgagca gcgtggcggc ggccagcgcc
    16501 gccggcccgc tcacggtgag cagcgcacgg gccgtccacc aggcgcgcgc ccgcgggtcc
    16561 acgggatggc gcggcgccct gagccgcacc acgcacgacg aacccttttc caagtcaatc
    16621 gtattgccaa acacagggcg ctaagctatc gcaatacaac tgacctgtaa acgagaaccg
    16681 tcgaacgaga gggaccgctc cccgtgccca agcgcgtcga ccacgacgaa cgccgccacc
    16741 gcatcgccga ggccctgtgg cggatcgcgt ccgagcgcgg gctggacggc gcgagcctgc
    16801 gtgacgtggc ggcggaggcg ggcatctcgc tggggcagct ccagcactac ttccgcacca
    16861 aggacgacat gctcgtcttc gccctcggcc acatcagcga gctggccgcg cggcggatcg
    16921 gcgcccgcgt cggctccctg gccggagacc cctccccccg gacgctgctg cgcgagacgc
    16981 tcgcggagat gctgccgctg gacgacaaga gccgcaccgg tcagctggtg cagatcgcct
    17041 acttcgtccg cgccgtccac gacgagcggc tgcgccggca cgccaaggag ggcatcccgg
    17101 cgctgcggga gttcttcgcc gcgcagatcc ggcgcgcgat ggaagggggc gacatcgccg
    17161 ccgaccgcga cccggacacc gaggcgatgc tgctgatctc cctcgtggac ggcctgaccg
    17221 gctacgtcct gctcgacgtg ctgccgggcg aggaggcgat gcggctggtg gacgcgcacc
    17281 tggaccggct gttcacctga attcgcctaa agaagcgggc tcagcggcgc gccgccctgt
    17341 tgcgtccccg ctgccccggc gcgagcgcct cggccagttc gtcgagcgcc tccaccatca
    17401 gctccgagcc ccgcacggcc accccttcgt cgccgacccg cgcgacccag gcggccagtg
    17461 ccacgtgcgg cccggaccag tccgggcgcc gccgctcccg taccgccgtc acggcgtccg
    17521 gcagcgcggc gcgcagggca gccgcgaact cgtcggcccc ggggtccggt tcggcgtccg
    17581 ggcccggcag gtgggcctcc atcagcatcg ccgcccgccc cagcgtggcc agcgccgact
    17641 cggccgaccg ttcggcagcg cgcgagatgc cccggtggcg cacgggctcc tgctgcgcgc
    17701 gggcggccgc ctcctcccac tccagccgcg ccgcccgcgc gtccagcagc gcttctcgga
    17761 cccgccgctt ccggttctcc ggccgggcgt gggcgtcgag gaccgccagc gcgtagtcgc
    17821 cgttggtgcg gagccagtcg gccagccggt cgcgcagccg gggcgtctcc caggtgggcc
    17881 acagcgcgta ggcggccagc gccagcaccc cgcccagcag cgtcagcgcc agcctggcct
    17941 gcacggtctg cgaccagccc tcccccgcga tgccgagcag gaagacgatg tacgcgccga
    18001 tgcacgcgga caccacgatg tagcccgtcc gcatcagcag gtacagcagc cccacgctca
    18061 ccacggccag cgccgcacag accggggggc cggggtgggt gagcgccatg atgcccgcgc
    18121 ccgcccagac gccgacgagc gtgcccacga agcgggccac gccgcgctgg taggtctggg
    18181 cgaagtcggg ccgcatcacc atcaccgagg tcatcggcac ccagtagccg tggcccagcg
    18241 gcagcaccgt gccgagcaga tagcccgcac aggccaccgt cgtcacccgc accgcgtgcc
    18301 ggccgaccgg cgaggaccag cgcgcctcgc gccgcagcgc ccgccaggcc acggggacga
    18361 gcccggccac ggtgggccgc aacagatgcc gccgctccgc ccccgccgtc ggccgggtgg
    18421 cgcgcagggg ctcgtcgccg gcctccacga catcggccag cagcgccatc agccgcagcg
    18481 ccgagcggcg ggcggcgccg tcgaggcgcg gcccggactc gggcacctcc agggtggcca
    18541 tcacctcggg cgtcacccgc acgggccggc cccgccggat ggcgcgcgcg acggcgtcga
    18601 ggacgtcggc ggcggcaccc agcagctccc gggcccggtc ccgcccgggg ccctccgggg
    18661 gcgcgcccac gacggggtcg gcgagggagg cgagcaccgg ccggatccgc tcggcgaccc
    18721 cgcgcgcgcc gcccagctgc cgcggtctgc tgcgggcctg gcgcggggtc agctcggcgg
    18781 cgctgcgggc gtgcatcagc ggctgcgggt cgaagtgggc gaccgggtcg tggcgcagcc
    18841 ggcgcgcgta gtccgcctcg gcggccagcg cgtccgcgag ggcgtcgcgc tggcggcccc
    18901 aggggcggat ggggaagacg acgatgagcg ctgcctgcac caggccgccc acgaggatca
    18961 gcgccgcgtg ctcggccgcc ccggcgacgg aggtgggcag ggtgacggtg acgagcatga
    19021 ccgcgatcgt ctgcgtggcg acgaaccccg tcaccgggcc gacggcccag gccatgcccg
    19081 acagcagggt ccacaccgcc agcagcgcga cgaagagggc gaggtgggcg gcggcgaggt
    19141 agccgaggaa agtgctgagg cccagcaccc ccgcgaccgc cagcgcgagc agggggcggg
    19201 gccgccagct gcgctggaag gtcgccaggc cggaggcgaa agcgccgaac gcggaggaga
    19261 cggcgagggc gggcgaaccg aaggccagca tcaggccgac gacgaccgcc acgccgcagg
    19321 cgccgcggac ggccacgagc ggttccaggg tgacgcgctc gatggtcagc cccgcgcggg
    19381 ctgtcttctt cagcgcgctg gcccaggtca tggggacgag cttacgtccc gtaccgggac
    19441 ggatcggggc aggccggtgg gccggtttgt gcccacccgt tccgcccttg cggaacgcct
    19501 gcccacaaac cggctgctgc cctatccgtg gtgcgggaag cccaggtcga cgccgccgtc
    19561 cgccgggtcc ggccagcggg tggtgacgac cttgccgcgg gtgtagaagc ggactccatc
    19621 gttcccgtag atgtggtggt cgccgaagag cgagtgcttc cagccaccga aggagtggta
    19681 gcccaccggc accgggatgg gcacgttgac gcccaccatg cccgcctcga cctccagttg
    19741 gaagcggcgt gccatgcctc cgtcgcgggt gaagatcgcg gtgccgttgc cccacggcga
    19801 ggcgttgacg atggccaggc cctcctcgta cgtctcggcg cgcagcacgc acagcaccgg
    19861 gccgaagatc tcgtcgcggt aggcgtcggc gtcggtcggc accttgtcga gcagggacag
    19921 gccgatccag tggccggccg cgtattcgac ggaacccgga ccgctgaagc ccgtgccgtc
    19981 gaggacgacc tccgcgccct gggccgcggc gcccgccacg taggcggcga ccttgtcgcg
    20041 gtggtccttg gtgatcagcg ggcccatctc cgaggcgggg tcgtcccccg ggccgatctt
    20101 gatcttctcg gcgcgttcac ggatcttcgc caccagctcg tccccggtgc cgccgaccgc
    20161 gacgaccgcc gagatggcca tgcagcgctc gcccgccgag ccgtaggcgg cggagacggc
    20221 ggcgtccgcg gcggcgtcga ggtcggcgtc gggcagcacc agcatgtggt tcttggcgcc
    20281 gccgagggcc tggacgcgct tgccgttggc ggaggcggtg gtgtggatgt accgggcgat
    20341 gggcgtggag ccgacgaagg agacggcggc gacgtccggg tgctccagga gccggtcgac
    20401 ggcgacccgg tcgccgttga cgacgttgag gacgccgtcc ggcagcccgg cctcggcggc
    20461 gagctccgcg agacggatcg cggacgaggg gtccttctcg ctgggcttga ggacgaacgt
    20521 gttgccgcag gcgatggcga gcgggaacat ccacatcggc accatcgccg ggaagttgaa
    20581 cggcgtgatg cccgcgacga caccgagcgg ctggcggatc gcggagacgt ccacccggct
    20641 ggagacctgc gtggacagct cgcccttgag ctgctgggtg atgccgcagg ccagctccac
    20701 gacctccagg ccgcgcgcga cctcgcccag ggcgtcggag tggaccttgc cgtgctcggc
    20761 ggtgatcagc cgggcgagtt cctcgcggtg ggcgtcgagc agggcgcggt agcggaagag
    20821 caccgccgtg cgctgcgcca gggaggagcc gccccaggtg ccgtaggcgg ccttggcggc
    20881 ggccacggcc gcgtcgacct cctcggcggt ggcgaacgcg acgcgcgtgg tgacgacgcc
    20941 cgtggccggg tcggtgaccg gcccgtacgt gcccgaggtg ccctcgacgg acttgccgtc
    21001 gatccagtgg ttgacggtct tcatctctac tgcgacctct cttgcctcaa aggccttacg
    21061 tcaaaggtaa cgacggcggg cggctgcgtt gcggtcgtac tcctcccggg ccgacacggc
    21121 cgccgggcgg gtcgcggtct cggcgacggg cacatcccac cacgcctggg cggggggcgc
    21181 cccggacaca gtgtcggccg tttcggtctc cacgtagaca catgtgggcc ggtcggcggc
    21241 gcgtgcctcc gccagcgcgg cgcgcagctc gtgggcggtg cgggcacgga gcacgctcat
    21301 gccgagtgag gcggcgttgg ccgccaggtc gaccggcagc ggggcgccgg tgtacgtgcc
    21361 gtcgggcgcg cggaagcggt aggcggtgcc gaagcgctcg ccgccgacgg cctccgagag
    21421 gccgccgatg gaggcgtagc cgtggttctg caccaggatc accttgaccg ggatgccctc
    21481 ctgcacggcg gtgacgagct cggtgggcat catcaggtac gtcccgtcgc cgaccagcgc
    21541 ccatacgggc aggccgggtg cggccagggc gacgccgatg gcgccgggga tctcgtagcc
    21601 catgcaggag tagccgtatt cgaggtggta ctggcggcgg gagcgggtcc gccacagctt
    21661 gtggaggtcg ccggggaggg agcccgccgc gttgacgatc acgtcctcgt cgccgacgac
    21721 ggagtccagc gcgccgagca cctgcgcctg ggtgggccgg gcgccgtcgc cccggccgtc
    21781 gtccggggcg tacgcgcggg cgacggtcgt ctcccactcg gccttcccgg cggtgtacgc
    21841 gctggcgtac gcgtccggca cgcggtgtcc cgcgacggcc tccgtgagcg cctccaggcc
    21901 gctgcgggcg tcggcgacga gcgggagccc ggcgagcttg tgggcgtcgt acggggcgat
    21961 gttgaggttg acgaagcgga cgtccggggc ggcgaagagg gtcgcggagg cggtggtgaa
    22021 gtcgctgtag cgggtgccga cgccgatgac gaggtccgcg gcgcgggcga gggcgtcggc
    22081 gacggccgtg ccggtgtgac cgatgccgcc gacgtccgac gggtggtcgt ggcgcagcga
    22141 acccttgccc gcctgggtgg aggcgacggg gacgccggtg gcgtcggcga acgcgcgcag
    22201 cgcgtcctcg gcctcgctgt ggtggacgcc gccgcccgcg atcagcaacg gccggcgggc
    22261 ggcccgtacg gcccttgcgg ccgccgccag ttcggccggg tcgggggcgg ggcggcggac
    22321 gtgccagacg cggtcggcga agaactcctc gggccagtcg tacgcctcgg cctggacgtc
    22381 ctggggcagg gcgagggtga cggcccccgt ctccaccggg tcggccagga cgcgcatggc
    22441 ggcgagcgcg gcggggatca gcgcctcggg gcggacgatc cggtcgaagt accgggagac
    22501 ggggcgcagg cagtcgttga cggagacgtc gcccgctccg gggtgctcga gctgctggag
    22561 gacggggtcg gcggggcggg tggcgaaggt gtcgccgg
//
