LOCUS       NZ_CP034587            22583 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 824442
            Orig. end                         :: 847025
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22583
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="10"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22583
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12583](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12583
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    881..895
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            1273..2217
                     /locus_tag="EKH77_RS03370"
                     /old_locus_tag="EKH77_03370"
     CDS             1273..2217
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (21-110). E-value: 8.6e-09.
                     Score: 27.5. Matches aSDomain:
                     nrpspksdomains_EKH77_RS03370_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016826367.1"
                     /locus_tag="EKH77_RS03370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03370"
                     /product="oxidoreductase"
                     /protein_id="WP_126912947.1"
                     /transl_table=11
                     /translation="MRHSPPRWTTEDMPNLEGRLAVVTGATGGIGYVTARELAHAGAEV
                     VVTGRDAGRARRAAEDMASEVPGARVRPDLLDLADLASVTGFAHRVEHGGRPVDLLVNN
                     AGVMGIRHRATTKDGFELTVGTNHLGHFALTGRLLPQLLAAPAPRVVTVSAAISRSAIA
                     ELSDLQSTRKYRALNAYAKSKLANVLFALELQRRADAAGVALTSVAVHPGFSATGLQRH
                     ATRPVRALARLLPGHFVGQSVESAALPTLYAATAADVAPAGFYGPTGRFETRGAPGPVD
                     LPVPAASTTLAARLWHTSESLTHVRYRWPEGAS"
     CDS_motif       1336..1422
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH77_RS03370_0001"
                     /evalue="9.50E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH77_RS03370"
                     /protein_end="50"
                     /protein_start="21"
                     /score="24.7"
                     /tool="antismash"
                     /translation="VVTGATGGIGYVTARELAHAGAEVVVTGR"
     aSDomain        1336..1602
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS03370_PKS_KR.1"
                     /evalue="8.60E-09"
                     /label="EKH77_RS03370_PKS_KR.1"
                     /locus_tag="EKH77_RS03370"
                     /protein_end="110"
                     /protein_start="21"
                     /score="27.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGATGGIGYVTARELAHAGAEVVVTGRDAGRARRAAEDMASEV
                     PGARVRPDLLDLADLASVTGFAHRVEHGGRPVDLLVNNAGVMGI"
     CDS_motif       1678..1734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH77_RS03370_0002"
                     /evalue="8.50E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="EKH77_RS03370"
                     /protein_end="154"
                     /protein_start="135"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="GRLLPQLLAAPAPRVVTVS"
     gene            complement(2226..2888)
                     /locus_tag="EKH77_RS03375"
                     /old_locus_tag="EKH77_03375"
     CDS             complement(2226..2888)
                     /EC_number="7.4.2.11"
                     /GO_function="GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942101.1"
                     /locus_tag="EKH77_RS03375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03375"
                     /product="methionine ABC transporter permease"
                     /protein_id="WP_126912948.1"
                     /transl_table=11
                     /translation="MKADWNTFWVKVVDATGETVYMVLVTLALSAVLGTAVGLALYATR
                     KGGLLRNRAVFAVLSALVNVIRPVPFIIAIVALSPVTRGVVGTMIGTEAAIFPMTVVAT
                     FGVARIVESNLLSVEPGVIEAARSMGAGPLRVLLTVLVPEALGPLVLGFTFMLVALIDF
                     SAVAGTVGGGGVGNLAMTYGYLRFDTSVMVVTVAVLVLLVQIAQLLGNFLARKVLRR"
     gene            complement(2885..3895)
                     /locus_tag="EKH77_RS03380"
                     /old_locus_tag="EKH77_03380"
     CDS             complement(2885..3895)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942104.1"
                     /locus_tag="EKH77_RS03380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03380"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_126912949.1"
                     /transl_table=11
                     /translation="MIELRDVTKVFPAAKKSPGAGAPAVDGVSLAVERGSVFGVVGHSG
                     AGKSTLLRLINYLETPTSGTVLVDGQDLGALGERRRREVRRSIGMVFQQFNLFRSRTVL
                     GNVAYPLRLSGLSRAEARERAGEALRFVGLDAHARRYPEQLSGGQRQRVGIARALATEP
                     GVLLCDEATSALDPRTTGEVLDLLRRVNGELGVTIVLITHEMEVVRSLCDHVAVMAAGK
                     VVETGGVHDVFSRPAHPVTGTFVRSALHDVPDAATLARLRARHPGRLVTVPVGGGEDLS
                     RLFREHDVDFTIAHAGVTEVQARTLGGVTFELRGAERDVAAVLARLTAEEEVVAR"
     misc_feature    complement(3862..3879)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    3878..3892
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.79"
                     /tool="antismash"
     gene            complement(3899..4777)
                     /locus_tag="EKH77_RS03385"
                     /old_locus_tag="EKH77_03385"
     CDS             complement(3899..4777)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942105.1"
                     /locus_tag="EKH77_RS03385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03385"
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_126912950.1"
                     /transl_table=11
                     /translation="MRISLSRRRAAAASVAAALTLLLSACGMSDAAGGDRVRIGVNGAD
                     PEWDVLAEEAKKEGIDVKIVNFDDYQLPNRALADGDIELNAFQHLAFLSEFNKRNRTDI
                     VPVTSTSVAPMGLYSLKHKKVEDIPDGARVAIPNDPSNQGRALLVLRQAKLIGLKDKAG
                     IHGTPDDITDNPKHLKITPVDAQQTPRALKDTAASVINAGVAELAGYKVEQAVFHDDPE
                     SAVARPYVNVIAARAKDKDNKNIRKIVELYRSRTVQEAVRKSAHGARYVLDIPQGELRH
                     ELDRLTRQDRG"
     misc_feature    complement(4763..4778)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.07"
                     /tool="antismash"
     misc_feature    4875..4888
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.54"
                     /tool="antismash"
     gene            4971..5924
                     /locus_tag="EKH77_RS03390"
                     /old_locus_tag="EKH77_03390"
     CDS             4971..5924
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS03390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_03390"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_126912951.1"
                     /transl_table=11
                     /translation="MVTTRHRPRPLNHPKMATGFDQVLHALRGRKPRRAAGLPGEPRWR
                     AEFVARDAQGPRLGLQDFGYASHELSRGYGAVDDTALVGPVRLLTPDGLACLTEVCDRL
                     ESSAGTARFITTRRVRNADLMSAFINNMIRDKGFLLACSRLAGVPLIPHPLRIPTVQIN
                     YFEADGRADIVKWHHDGMDHVLTLQLNGYEDYDGGRFHYFLGRVDEFTGARQGDPRIRE
                     APCGERGAALFLHGSRIYHAVTPVTRGRRVTVVVSFLCPYFARRDSNTFWHLAADDGIP
                     ATIPGWLRLKWPVRDPAMDYSLRAGSPVVTWEDLRG"
     gene            complement(5899..6591)
                     /locus_tag="EKH77_RS03395"
                     /old_locus_tag="EKH77_03395"
     CDS             complement(5899..6591)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049072.1"
                     /locus_tag="EKH77_RS03395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03395"
                     /product="response regulator transcription factor"
                     /protein_id="WP_126917855.1"
                     /transl_table=11
                     /translation="MRVVIAEDHYLVREGTRRLLEDTGDISVVSAVGDAAELLDAVEEL
                     RPEAVIADIRMPPGHHTEGITAAHAIRAGHPGIGVVMLSQHADENYAFDLFRRGTDGLA
                     YLLKERIGELDELLRALREVAAGRSVVDPRIVEVLMGSHTRAADAPLACLTRRELDVLR
                     HMAEGKTNRAIAAELVLSESTIEKHVNSTFAKLGLAEEPQLHRRVSAVLAYLRHAPRGP
                     ATPAGPPR"
     gene            complement(6608..8677)
                     /locus_tag="EKH77_RS03400"
                     /old_locus_tag="EKH77_03400"
     CDS             complement(6608..8677)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="EKH77_RS03400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03400"
                     /product="ATP-binding protein"
                     /protein_id="WP_126912952.1"
                     /transl_table=11
                     /translation="MRGNGRAIQVAAFSGGLCLLWAVTTGAFLLRNNTVTLPWILGSVL
                     PCYCAGLFAWWHAPASPVARRLLLIGAALAVSIGIRCTSALLTTSFGWDLTAPENGLPS
                     LTASCLVLPTEWDNLAVSILVVHLLALLPDGRPRFRYERPVLRSLWALLALPFLLPLAG
                     VPTRVVEYVVFYYPEAWLPGVGAALLVLRALRARAAGDRDLAGVLPVAAAATVLFLGRG
                     ASRLFRPWHGETGVLYLVGSALGALPYVLISLSVVYAAFRYRLLGVDIVIRRSVVYGTL
                     WLIISGWYLGMAMTLGLTAGQYFPIGLSVLVAVTATALFQPVRERLNRLAQRRVFGERL
                     SGFELLVQFGSALEHAYDLSRLAPQLAAGLQQGLTLSWTRVRLGGGDLPVHLGTAGEPP
                     GRGRPAGPGGGFPLRYGDDVLGLIEYGPKAEGRFTPEDHDLVETLARQAALAVHNARLA
                     AELSTRVLEVQRQAGELDASRARIVHAQDSERRRIERRLHDGIQQDLVALVAKLRLARN
                     RLGRGGDVDAVLTEVQDDAYRVIDELREVAHGIHPPVLTDQGLVAAVTSRARRMPIPVT
                     VRVDESLDRVRFALEIEESAFYLVSEALTNVLKHARAGRVTIGISRADGWLVVEVVDDG
                     VGFPCDTTGGSGLTGMRDRIEAVGGDLRITSRAGGGTTIRSRLAERLREEETVD"
     misc_feature    8890..8905
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.98"
                     /tool="antismash"
     misc_feature    8896..8911
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.49"
                     /tool="antismash"
     gene            8906..9967
                     /locus_tag="EKH77_RS03405"
                     /old_locus_tag="EKH77_03405"
     CDS             8906..9967
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="EKH77_RS03405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03405"
                     /product="radical SAM protein"
                     /protein_id="WP_126912953.1"
                     /sec_met_domain="Fer4_12 (E-value: 2.4e-06, bitscore: 26.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.6e-16, bitscore: 57.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVSSGPEVVVWDTTYACPLRCSHCYSESGRRAPRQLSHEDMLRV
                     ADALISLNPRVVALSGGEPLVVKGIFEVAGRLSRAGVRTAVYTSGWIMEPWMAAELGSV
                     FDEVIVSLDGATAQVHDRIRGRRGSFDRALSALTLLDGVARERARRGRAPLWFGIDCVV
                     VRSNFPQLEEFCTAIAPRFPELRTLTFNAAVPEGLASRPEFCRFELLDDTQVAELTSDG
                     RRARLQRLAPAGVRVFTTDNQNLVMRPDRFASGVDTLVMQIEPDGDVRALPVYEGTVGN
                     ILQESPLDLWHRGVSRLSDPFVVETLSAVRTMQDWAAAVRRMDYHFGSPEVRSRIDRRA
                     IRTNPPEFSALAH"
     gene            10001..12583
                     /gene="lanKC"
                     /locus_tag="EKH77_RS03410"
                     /old_locus_tag="EKH77_03410"
     CDS             10001..12583
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="EKH77_RS03410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03410"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_126912954.1"
                     /sec_met_domain="micKC (E-value: 4.7e-142, bitscore: 473.3,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-08, bitscore:
                     32.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLKDYDRFCLADPVFYEVPERYPDDHERFAAARREPPRGWQRG
                     ESGWWITLRPGPAAPGAGWRIHVSVALPELARAVEIVWGHCVAHALPFDFVRSRATARE
                     LCGHRAEPLPGNRLITVHAGDGATLTRSLEELGVLLAGLPGAYVAGALRHGPGPLYVSH
                     GPPGPEGLPRPGDRTVFAPPGGVPLPEPLRADLEALRARPAGGFPYRAERALGRSHGGG
                     TYLAVDKRTGERVVLREARPYAGLDERGEDAVTRLDRERAARERLVGLDCVPRVLGHLT
                     HAEHRFLAEEFIEGTSLLRAAADAFPLTSRERAAREAAPYTAWALDVVDRTERALHALY
                     AHGLRLGELRPENIVVRPDGRVALVGLGTLTDAGDDRAPATGDPGFAAPPGLTAPDALR
                     HLLDRLRLWLFLPVPHRGPGKLHTLTAAIERHYPVPRGFGAGLLTGLWPEGHPAEDDRA
                     GALLAADRPDWPAIRDSLVRGIHATATPDRADRLFPGGPTGTGELGGPGLAHGAAGVLY
                     ALHRTGARVPEEYTAWLLDAVRRDPEPAPGLHEGLHGVAFVLDALGLRAEALDVLGLCP
                     PERDAVPDAGLAAGRAGIALTLLHFAGATGDPALLTRALGLAGELGRAVEDGPPPAPPG
                     RPAPYGLLHGATGAALLFLRLYEHTGDASLLGLAGRALRHDLVRLRTLPDGMLTLFDGT
                     ANLPYLHGGSTGLAFVLRDLLRYRPDPRLAAVLTSLRLTCDAVYVRNAGLLRGRAGSVA
                     VLAALGEPVTGTALGGQIRRLSWYAQAYRGHLAFPGFRMLRLSADLATGAAGVLLALGS
                     AFGATGPVLPFLDPRPVAVPPAREGGERRVGDPGAAGAGGGDPRPVAV"
     gene            12715..13767
                     /locus_tag="EKH77_RS03415"
                     /old_locus_tag="EKH77_03415"
     CDS             12715..13767
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS03415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_03415"
                     /product="hypothetical protein"
                     /protein_id="WP_126912955.1"
                     /transl_table=11
                     /translation="MLAQGHLVADPLFVDAPERVEDTAVRFAHAARPAPPGWRRAERDG
                     WVMLRPRDARLPPQGWKIHVSATAEEASRAVATVWEYCVARGIGFKFLRSRTLLALVNS
                     KRAPRSAGGKLVTVYPRSEELLERALEELSTLLRGVKGPYILSDLRWGEGPLYLRYGGF
                     TPRFCFSGDGEYVPAVVRPDGRAVPDVRGAAFKVPPWAGVPPFVAGRIRAARADGAGGF
                     PYRVEKALRFSNSGGVYRALAPGTGRRVVLREARPYAGVDDNGMDAVARLGREHAVLER
                     LAGLGCVPRVLARTRHWEHHFLVEEFVEGNGWRRPWAAATPSSGRARAARSWPRTPTGR
                     ARSSPASRRR"
     misc_feature    13123..13125
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13662..15230
                     /locus_tag="EKH77_RS03420"
                     /old_locus_tag="EKH77_03420"
     CDS             13662..15230
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS03420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_03420"
                     /product="protein kinase/lanthionine synthetase C family
                     protein"
                     /protein_id="WP_126912956.1"
                     /sec_met_domain="Pkinase (E-value: 1.3e-09, bitscore: 36.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRRHPLFRPGASRAELAAYTDWACAVVTRLEEAIAALHGRGVVF
                     GDLQPGNVLVRPDGSVCLVDFETSFGMDENFTPALGTAGFTAPWARTGPAVDAYALDCM
                     RLAVFCPLTELLRFDPRKHEQLIRHVEDRFPLPPGYGERLRAGLAPPPDPAPPPAPTWP
                     GAAAGPTGTWDEVLGSLCDAVVRSATPERADRLFPGDVRQFDGQGAALAYGAAGVLHAL
                     HRTGHGGGARFEGYVDWLARAAERADWPRPGLYDGLAGVAYVLDELGRPQQARAALARL
                     AAFDLRGCGAGLFGGLAGIGLAFAHFGDLRAAARLAERLARGLCEDVLAPVPAAGLMRG
                     WSGPALLFSRLFAETGEDRWLRWAEAALARDLAHCGVSPGRHVHVRAGRRRLTTLGGGG
                     AGVAIALHEYLRHREDPHFAGLRDRIRAGLGAELLLSSGLFEGHAGLLYALVHLGGPAD
                     AREAQLRGLGLHAVRFQGRLAFPMDGLLRLSMDLATGTAGVLLAVHAALRGTTAGASLP
                     LLRTG"
     gene            15384..15953
                     /locus_tag="EKH77_RS03425"
                     /old_locus_tag="EKH77_03425"
     CDS             15384..15953
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS03425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_03425"
                     /product="hypothetical protein"
                     /protein_id="WP_126912957.1"
                     /transl_table=11
                     /translation="MFGKRGIGVASVSLALIASCLGWAAPAAGAHDDHGAHGGHGGHGP
                     VTCQGRESTTYSPGLTLTPQSVGIRAATAYTCSDRPGHTIAATGSANGRSPESTCLGLH
                     APAGHEVLRYGDGSVSEISYPVGNAERVLGVNTVMLKGVVVAGRDKGAEAERFVEVAPA
                     QGLPLACLTPEGVRRSTGVTQLRIIP"
     gene            complement(16021..17571)
                     /locus_tag="EKH77_RS03430"
                     /old_locus_tag="EKH77_03430"
     CDS             complement(16021..17571)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953713.1"
                     /locus_tag="EKH77_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03430"
                     /product="MFS transporter"
                     /protein_id="WP_240667201.1"
                     /transl_table=11
                     /translation="MARASGDPHSTTGPAPGRWAMLAVLCASLLLVAMDATILNVALPS
                     LIDDLRPGPLEQLWIIDIYGLILGGLLVTTGAVGDRWGRKRLFLVGFVLFGVASVLAAT
                     AHSSFQLIGGRVLLGLGGAMVMPSTLSLIRNIFTDARERALAIGVWAAVAGAGACVGPL
                     VGGFLVEHFEWQAAFWVNVPVVVVTVAVGVRLLPEYRAPHPGGLDWPGAGLSIVGIVAL
                     AWGIKHVAKGSPNPSDVGALVLGVALLALFAWHQLRLEDPLLDVRLFREGPFLAAALAT
                     LLAMLAIGAALFLISLWLQYVHGYSPSEAGLRTLPSALAMLVGSLSSPWLMHHAGVRAV
                     LATGLGALAAGFLLLALAPEPTTYPVVAVVLAGLGLGDGLAITASASVLVSAVPAERAG
                     QAGAVSETAYELGVGLGVALLGSIHGAVFSHRMTDRTANLPLRGHDLDTARGSVGGAAD
                     VARQVGGDTGRRVLTAARGAFDHALTTTAYVSAGIVVAVTLLTVFMVPRGFKVTGGGH"
     gene            complement(17714..18340)
                     /locus_tag="EKH77_RS03435"
                     /old_locus_tag="EKH77_03435"
     CDS             complement(17714..18340)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946917.1"
                     /locus_tag="EKH77_RS03435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03435"
                     /product="response regulator transcription factor"
                     /protein_id="WP_126912958.1"
                     /transl_table=11
                     /translation="MPDSATRVTVVVADEHPAYREGVVRGLRADGRIDVRAEAEDGVAA
                     LTAIRELVPHVALIDYRLPKMDGVAVIHAVVGEGLPTRLVLLSAATDATVVYRALREGA
                     AGYLAKDAKRPEFVEAVLAAADGRPVPSEAGPRPAADGDAAALSERERQVLRGFAEGKG
                     IPQLAAELRLAASTVKTVTHRLYEKLGVPDRAAAVAEAVRRGLLD"
     misc_feature    18292..18306
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            complement(18429..18668)
                     /locus_tag="EKH77_RS03440"
                     /old_locus_tag="EKH77_03440"
     CDS             complement(18429..18668)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547387.1"
                     /locus_tag="EKH77_RS03440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03440"
                     /product="antitoxin"
                     /protein_id="WP_126912959.1"
                     /transl_table=11
                     /translation="MSLIDTLKGLVGKGKAAAAENPEKVEQAVDKAGTFIDEKTGHKYS
                     DKIEKGKEAAKNAIPGEGEPETPPPPAPEPPAQP"
     gene            complement(18765..20972)
                     /locus_tag="EKH77_RS03445"
                     /old_locus_tag="EKH77_03445"
     CDS             complement(18765..20972)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024905.4"
                     /locus_tag="EKH77_RS03445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03445"
                     /product="FUSC family protein"
                     /protein_id="WP_126912960.1"
                     /transl_table=11
                     /translation="MARTPPAGAARRAAWATLAGCAGFYGFAHALGDRTVGLYATFGVL
                     PLVLFSQIPGPARHRTRVLLAMVPVGWIMVTSGTLLAVRGWAAAAGMFVVGFLVAFAAT
                     AGPGPAGLSVACQLFYILPCFPPYAPETLGSRLAGLTAGILLTALVDRLLDLLGLREPP
                     PTPYRVRLGRATAAVADSCAAAARGGEDVRPAAELALQEARPSRIPPAERPTSPSARDR
                     ALNHTRACVRHVHDQLDRFCRGPGAPGPAGPDDPATALLERTATALRPVATGLTSGTPP
                     PDGNDGNDGNDGNDGNDGTDDDALRRAVAAFDAVRADEIPGAPPERLRRDAVVRSAAEG
                     ARLAGQASRIALGARSTTAGAGRDGPFWYAAVPAPELWWHRMRVHLTLRSVHLQNALRV
                     ATAMAGARLLVGALGLSHGFWVLLATLSLMRTSAADTRTALRPAVTGTTAGALLAALAL
                     RAVGDVPLFYAVALPVVLLVGFTAAPLLGPAWGQATFTVVIVLMFAQLSTPQWQLSAVR
                     LVDVLVGGAIGVLASLLAWPRGAGGELRCAVADFLAAGAAGCRGVTDLLCGRPAPADPL
                     RPVRVAMLLAEASYCQYQGERLLRRAVDPPWEMAMLAGYHMLRGGELMLLRQGAALGAT
                     PLSPGAAAELTFLADRVADDALRAAEALRAPAPPRPAPGIPGPPPRPAATSGLLRGAAL
                     HAGHVDAARVLLTVDAEAWLTGVAEDVARIVRAPYAVTRSG"
     gene            complement(21165..21779)
                     /locus_tag="EKH77_RS03450"
                     /old_locus_tag="EKH77_03450"
     CDS             complement(21165..21779)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358950.1"
                     /locus_tag="EKH77_RS03450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03450"
                     /product="DsbA family protein"
                     /protein_id="WP_126917857.1"
                     /transl_table=11
                     /translation="MKLVYVFDAYCGWSHGFSATLTETARRHPELPVEVVSGGLFTGAR
                     RVPIREFGYVQGANAKIAELTGAEFGAAYDRLIADGSFVMDSEAAARGMAALRQAAPDR
                     AAELAAALQDAFYADGLSLSEESTYRTVAEAAGLDADAVAAAFSAPGAAKAARADFRRA
                     AEYGVQGFPTLLAVDGERVTVLAVGHATADQVAARLVAAGS"
     misc_feature    complement(21831..21848)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(21884..22378)
                     /locus_tag="EKH77_RS03455"
                     /old_locus_tag="EKH77_03455"
     CDS             complement(21884..22378)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151593.1"
                     /locus_tag="EKH77_RS03455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03455"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_126912961.1"
                     /transl_table=11
                     /translation="MAHESGIATAREAADDGLVLAFGRLQGAANRLEYILGRAIEEECG
                     ISHLMFEVLLILGRAGEAGLPMRAIAQERVLSTGGVTRLVDRMEAAGLVVRDADPGDRR
                     GRLVRLTPAGEETAVRAARIHRENIRRFFLEPLPEAHRERFAEDLKVLSHAARDALPRL
                     R"
     misc_feature    complement(22348..22362)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.13"
                     /tool="antismash"
ORIGIN
        1 ggatggccga gtactgccgg gaccgcttcg aggaggcccg cgaggccgcc gaggccctgg
       61 gcgtcgaggt cgcccacgta ccggcggtgg tcaactcgat cgcggccggt acggtccggc
      121 tgagcaccgg tcaggagctg tacgccgacg ccgtcgtcgt ctgcacgggc gtccaccgcc
      181 cccgcgtccc ggacggcttc gccgccttca ccgggcaccc ccgctactcg cccgccccct
      241 accccgccgc ccggctgcgc gaccccgagc tggggccgcc gcccggagcg gaggtcctgg
      301 tcctgggcag ccgccagtcg gccatcgacg cctccctgct gctgtgccgg gagggccacc
      361 gggtgacgat ggcctcgccc tcgggcgtac tgcccgccgt acgggtctcg ctgggcgcgc
      421 ccgtagggga cttcccttcg ctggagggcc tcgcgcggct cgacccggac gatcccctgc
      481 tggaggagaa ggtgcggcgc gccgtcgtgg aggccgtccg gtcgctcgac ccgaccccgc
      541 tgcgcctgca gtcctcgtcg gccggcgacc ccgtggcgcg gctgcgcgag gagacggcgc
      601 tggtggaggc gggcgcgtgc gcctggccgg gggccgtcat ggccgcgctg gaggcggtca
      661 tcgagctggg cgcccggctg cccgccgagc ggcgggcggc gctgctggag cgccacggct
      721 ggttcgtcgc ccggtatgcc acggcgatga cggtcgtcaa cgcgcgcagg ctgctcacgc
      781 acatcgactc cggggcgctg cgcctggccg gcggctaccc ggacgcggtg gccttcgagg
      841 cgggcgcctg gcgggtggag tggcccggtg ggggcgggcc ggagcgcttc ggccacgtgg
      901 tgaacgccac gggcttcgac cagccccggc tgtactggtc ggaggacggc accgcgctcc
      961 acccggcgga gccgccgcgc cactccggca ccgtggactt cctggcggac gacctgcgcg
     1021 tccggcggag ccccggggcc cggcccgagc gggtgtgggt ggtgggtgtc ggaacgcacg
     1081 tacggtttcc gttctcgaac cacctgcgcc aggtggtccg gcaggcccgc cgggtcgccg
     1141 gggaggtatc ggggacggcg gacggcaccg gggtgtgagg cggggccgcc gccgggcgcg
     1201 ccttcccctc gggcgccggt cgggcggcgg acaatacggt cgcccgtccg cgaccggccg
     1261 ccgaggagtc gcatgcgcca cagcccgccc cgctggacca ccgaggacat gccgaacctg
     1321 gagggccggc tggccgtcgt gaccggcgcc accggcggca tcggctatgt caccgcgcgc
     1381 gagctggccc atgcgggcgc cgaggtcgtg gtgacgggac gggacgcggg ccgggcgcgg
     1441 cgggcggcgg aggacatggc gagcgaggtg ccgggcgcgc gggtgcgtcc ggacctgctg
     1501 gacctcgccg acctggcctc cgttacgggg ttcgcccacc gggtggagca cggcgggcgc
     1561 ccggtcgacc tgctggtcaa caacgcgggg gtgatgggca tccggcaccg ggccaccacc
     1621 aaggacggct tcgagctgac cgtcggcacc aatcacctgg gccacttcgc gctcaccggc
     1681 cgactgctgc cccagctgct ggccgcgccc gcgccgcgcg tggtgacggt cagcgcggcg
     1741 atctcccgca gcgcgatcgc ggaactctcc gacctgcaga gcacccgcaa gtaccgggcc
     1801 ctgaacgcct acgccaagtc gaagctggcc aacgtgctgt tcgccctgga gctccagcgc
     1861 cgggccgacg cggcgggcgt cgcgctgacg agcgtggccg tccacccggg cttcagcgcg
     1921 acgggcctcc aacggcacgc cacccggccc gtccgcgcgc tggcccggct gctgccgggg
     1981 cacttcgtgg gccagtcggt ggagtcggcc gcgctgccga cgctgtacgc ggcgacggct
     2041 gcggacgtcg cccccgccgg cttctacggc ccgaccggcc gcttcgagac ccgtggcgcc
     2101 cccggcccgg tggacctccc cgtccccgcc gcgagcacca cgctcgccgc ccggctgtgg
     2161 cacacgtccg agtccctcac ccacgtccgc taccgctggc cggagggtgc ttcctgacgg
     2221 gcgggtcacc gccggagcac cttgcgggcc aggaagttgc ccagcagttg ggcgatctgc
     2281 acgaggagca cgaggacggc cacggtgacc accatcaccg aggtgtcgaa gcgcagatag
     2341 ccgtaggtca tggccaggtt gcccacgccc ccgccgccga cggtcccggc cacggccgag
     2401 aagtcgatga gggcgacgag catgaaggtg aagcccagca ccaggggccc gagggcctcg
     2461 gggacgagca cggtgagcag gacgcgcagg gggcccgcgc ccatggagcg ggcggcttcg
     2521 atcactccgg gttcgacgga cagcaggttg ctctcgacga tccgggcgac gccgaaggtg
     2581 gccacgaccg tcatggggaa gatggcggcc tcggttccga tcatggtgcc gacgacgccg
     2641 cgggtcaccg gggagagcgc gacgatggcg atgatgaagg ggaccgggcg gatgacgttg
     2701 acgagggcgc tcaggacggc gaagaccgcg cggttgcgga ggaggccgcc cttacgggtg
     2761 gcgtagaggg cgaggcccac ggccgtgccg agcacggcgg acagggccag ggtgacgagc
     2821 accatgtaga ccgtctcgcc ggtggcgtcg acgaccttga cccagaaggt gttccagtcg
     2881 gccttcatcg ggccaccacc tcttcctcgg cggtcaggcg ggccaggacg gcggccacgt
     2941 cccgttcggc gccgcgcagt tcgaaggtga cgccgcccag ggtgcgggcc tggacctcgg
     3001 tgacgccggc gtgggcgatc gtgaagtcga cgtcgtgttc gcggaagagc cgcgagaggt
     3061 cctcgccgcc gcccaccggg acggtcacca gccgtcccgg atggcgggcg cggagccggg
     3121 ccagggtggc ggcgtcgggc acgtcgtgga gcgcggagcg gacgaacgtc ccggtgacgg
     3181 ggtgcgcggg gcgggagaag acgtcgtgga cgcccccggt ctccacgacc ttgccggcgg
     3241 ccatcacggc cacgtggtcg cagagcgagc ggaccacctc catctcatgg gtgatcagca
     3301 cgatcgtcac gcccagttcg ccgttgacgc gccggaggag gtccaggacc tcgcccgtgg
     3361 tccgcgggtc gagggcggag gtcgcctcgt cgcacagcag cacgcccggt tcggtggcca
     3421 gggcgcgggc gatgccgacg cgctggcgct ggccgcccga gagctgttcg gggtagcggc
     3481 gggcgtgggc gtccaggccg acgaagcgca gggcctcccc ggcccgctcg cgggcctcgg
     3541 cgcggctcag cccggagagc cggagcgggt aggcgacgtt gccgaggacg gtgcgcgagc
     3601 ggaacaggtt gaactgctgg aagaccatcc cgatggagcg ccggacctcg cgccgccgcc
     3661 gttcgcccag ggcgccgagg tcctggccgt ccacgagcac ggtgccggag gtgggggtct
     3721 ccaggtagtt gatcaggcgc agcagggtgc tcttgccggc gccgctgtgg ccgacgacgc
     3781 cgaagacgct gccgcgctcg acggccaggg agacgccgtc gacggcgggc gccccggcgc
     3841 cggggctctt cttggcggcc gggaacacct tggtgacatc acggagttcg atcacggttc
     3901 agccccggtc ctggcgggtg aggcggtcga gctcgtggcg gagctcgccc tgggggatgt
     3961 cgaggacgta ccgggcgccg tgggccgatt tcctgacggc ctcctgcacc gtgcgcgagc
     4021 ggtagagctc gacgatcttc cggatgttct tgttgtcctt gtccttcgcg cgggcggcga
     4081 tgacgttgac gtaggggcgg gcgacggcgc tctcggggtc gtcgtggaag acggcctgct
     4141 cgaccttgta accggccagt tcggcgactc ccgcgttgat gacggacgcg gcggtgtcct
     4201 tgagggcgcg cggggtctgc tgggcgtcga ccggtgtgat cttcaggtgc ttggggttgt
     4261 cggtgatgtc gtcgggcgtg ccgtggatgc cggccttgtc cttgaggccg atgagcttgg
     4321 cctggcggag gacgagcagg gcccgtccct ggttggaggg gtcgttgggg atcgcgacgc
     4381 gggcgccgtc ggggatgtcc tccaccttct tgtgcttgag cgagtacagg cccatcggtg
     4441 ccacggaggt ggaggtgacg ggcacgatgt cggtgcggtt ccgcttgttg aactcggaga
     4501 ggaacgccag gtgctggaag gcgttcagtt cgatgtcgcc gtcggccagg gccctgttgg
     4561 gcagctggta gtcgtcgaag ttgacgatct tgacgtcgat gccctccttc ttggcctcct
     4621 cggcgaggac gtcccactcc gggtcggcgc cgttgacccc gatgcgcacc cggtcgccgc
     4681 cggccgcgtc cgacatgccg caggccgaca gcaggagcgt gagggcggcg gcgacggagg
     4741 ccgcggcggc gcggcggcgg gagagggaga ttctcatcgg agctcattcc acgaaagaac
     4801 gtacggggct tgctgtgccg atgatcgtag gcgctcaacg ccacttcgcc tggaaatgaa
     4861 aggaggcatt cacgttttcg caatagaagc aaggaagggc cggtcacggc gggagccgtg
     4921 gcgggaacac ctcccttgcc gcgcgccgca cgcggcgctg caatcggctc atggtgacga
     4981 cccgacacag accccgccct ctcaaccacc cgaagatggc caccgggttc gaccaggtcc
     5041 tccacgccct gcgcggccgg aagccccggc gcgccgccgg gctgccgggc gagccccgct
     5101 ggcgcgccga gttcgtggcg cgggacgccc aggggccgcg cctggggctc caggacttcg
     5161 gctacgcctc ccacgagctc agccgcggct acggcgcggt ggacgacacg gcgctcgtcg
     5221 ggccggtgcg gctcctcacg ccggacggcc tggcctgtct gaccgaggtg tgcgaccggc
     5281 tggagagctc ggccggcacc gcccggttca tcaccacccg ccgggtgcgc aacgccgatc
     5341 tgatgtcggc gttcatcaac aacatgatcc gggacaaggg cttcctgctg gcctgttccc
     5401 ggcttgcggg ggtgcccctg atcccgcatc cgctgcggat ccccaccgtg cagatcaact
     5461 acttcgaggc cgacggccgc gccgacatcg tcaagtggca ccacgacggc atggaccacg
     5521 tcctcaccct ccagctcaac ggctacgagg actacgacgg cgggcgcttc cactacttcc
     5581 tgggccgcgt ggacgagttc accggcgccc ggcagggcga tccccggatc cgggaggcgc
     5641 cctgcgggga gcgcggggcg gcactgttcc tccacggcag ccggatctac cacgccgtca
     5701 ccccggtgac gcggggccgc cgggtgacgg tcgtcgtctc cttcctctgc ccgtacttcg
     5761 cccgccggga ctccaacacc ttctggcacc tggcggccga cgacggcatc ccggcgacga
     5821 tcccgggctg gctccggctg aagtggccgg tgcgggaccc cgcgatggac tacagcctgc
     5881 gcgcggggag cccggtcgtc acctgggagg acctgcgggg gtagcgggcc cccgtggcgc
     5941 gtgccgcaga taggcgagga cggcgctgac gcgccggtgc agctggggct cctccgcgag
     6001 gccgagtttg gcgaacgtgg agttgacgtg cttctcgatc gtcgattccg acaggacgag
     6061 ctccgcggcg atggcgcggt tggtcttgcc ctcggccatg tgccgcagga cgtcgagctc
     6121 gcggcgggtc aggcaggcca gcggggcgtc ggccgcgcgg gtgtggctgc ccatcaggac
     6181 ctcgacgatg cgggggtcga cgacggagcg gcccgccgcc acctcgcgca gggcgcgcag
     6241 cagttcgtcg agctcgccga tgcgttcctt gaggaggtag gcgaggccgt cggtgccgcg
     6301 ccggaacagg tcgaaggcgt agttctcgtc ggcgtgctgg gagagcatga cgacgccgat
     6361 gccggggtgg ccggcgcgga tggcgtgggc ggcggtgatg ccctcggtgt ggtggccggg
     6421 cggcatgcgg atgtcggcga tgaccgcctc ggggcggagc tcctcgacgg cgtcgaggag
     6481 ctccgccgcg tcgccgaccg ccgagacgac ggagatgtcg ccggtgtcct ccagcagccg
     6541 gcgggtgccc tcgcgcacca ggtagtggtc ctcggcgatg acgacgcgca tcggtccctc
     6601 cgtcacctca gtcaacggtc tcctcttctc tgagcctctc ggccagccgg gagcggatcg
     6661 tggtgccgcc accggcacgg ctggtgatcc gcaggtcccc gccgaccgcc tcgatgcggt
     6721 cccgcatgcc cgtcagcccc gagcccccgg tggtgtcgca ggggaagccc acgccgtcgt
     6781 cgacgacctc caccaccagc cagccgtccg cgcgcgatat gccgatcgtc acccggccgg
     6841 cccgggcgtg cttgaggacg ttcgtcagcg cctccgagac caggtagaac gccgactcct
     6901 cgatctccag ggcgaagcgc acccggtcca gggactcgtc gacgcgcacg gtgacgggga
     6961 tcggcatccg ccgggcccgg gaggtgacgg ccgcgaccag tccctggtcg gtgaggacgg
     7021 gcgggtggat gccgtgggcg acctcgcgca gctcgtcgat gacgcggtag gcgtcgtcct
     7081 gcacctcggt cagcacggcg tcgacgtcgc ccccgcggcc cagccggttg cgggccaggc
     7141 gcagtttggc gacgagggcc acgaggtcct gctggatgcc gtcgtgcagc cgccgttcga
     7201 tgcggcggcg ttcgctgtcc tgggcgtgga cgatccgcgc gcgggaggcg tccagctcgc
     7261 ccgcctggcg ctgcacctcc aggacgcggg tggagagttc ggcggccagg cgcgcgttgt
     7321 ggacggcgag ggccgcctgc cgggccaggg tctccaccag gtcgtggtcc tcgggggtga
     7381 agcggccctc ggccttgggc ccgtactcga tcaggccgag gacgtcgtcg ccgtagcgca
     7441 gcgggaagcc gcccccgggg ccggccgggc ggccccggcc ggggggttcg ccggccgtgc
     7501 ccaggtggac gggcaggtcc ccgccgccga gccggacgcg ggtccagctc agggtgagcc
     7561 cctgctggag gccggccgcg agctggggcg ccaaccggct gaggtcgtag gcgtgttcga
     7621 gggcgctgcc gaactggacg agcagttcga agccgctgag ccgctcgccg aagacccgcc
     7681 gctgggcgag ccggttcagc cgctcccgca cgggctggaa cagggcggtc gcggtgaccg
     7741 cgaccagcac ggacagcccg atggggaagt actggccggc cgtcagcccg agcgtcatcg
     7801 ccatgcccag gtaccagccg ctgatgatca gccacagggt gccgtagacg accgagcggc
     7861 ggatgacgat gtcgacgccc aggagccggt agcggaaggc ggcgtagacg acggacaggg
     7921 agatcagcac atagggcagg gcgccgagcg ccgagccgac gaggtagagg acgcccgtct
     7981 cgccgtgcca gggccggaac agccgcgagg cgccccggcc gaggaagagg acggtggccg
     8041 cggcggcgac gggcagcacc ccggcgaggt cccggtcccc ggcggcccgc gcgcgcaggg
     8101 cgcgcagcac cagcagcgcg gcgcccacgc cgggcagcca ggcctcgggg tagtagaaga
     8161 ccacgtactc cacgacgcgc gtgggcacgc ccgccagcgg caggaggaac ggcagggcca
     8221 gcagcgccca cagcgagcgc agcacggggc gttcgtagcg gaaccggggg cggccgtcgg
     8281 gcagcagggc gagcaggtgg acgacgagga tactgacggc gaggttgtcc cactcggtgg
     8341 gcaggacgag gcaggacgcc gtcagggacg gcaggccgtt ctcgggcgcg gtgaggtccc
     8401 agccgaacga ggtcgtcagc agcgcggagg tacagcggat gccgatgctc accgccagcg
     8461 ccgcgccgat cagcagcagc cggcgggcga ccgggctcgc gggggcgtgc caccacgcga
     8521 acaggccggc gcagtagcac gggaggacgg aaccgaggat ccacggcagg gtgacggtgt
     8581 tgttccgcag cagaaacgct ccggtggtca ccgcccacag caggcacagc ccgccggaga
     8641 acgcggcgac ctgtatcgca cggccgttac ccctcacatg cacccctcac gcgcgacatt
     8701 atcgggggcg cccaggtgcc agtccagacg atcccgttcg gcgcgtatag cggaaaaccc
     8761 ccagtgagat cggaggattc cggggtacgc acggcggtcc cggcgcggca gactcggtat
     8821 atacgccctt tacccggccc tcggcggtcc cggtaggacg atcgactgtg cgattctgcg
     8881 attcaaggaa agccgaaagg gaaccatgag cgtgtcttcc ggtcccgagg tggtcgtctg
     8941 ggacaccacc tatgcctgtc ccctgcgttg ctcgcactgc tattcggagt ccggcaggcg
     9001 ggcaccgcgg caattgagcc acgaggacat gctgcgggtc gccgacgccc tgatctcgct
     9061 gaatccccgg gtggtggcgc tctccggcgg ggaacccctc gtcgtcaagg ggatcttcga
     9121 ggtcgcgggc cggctctcgc gggccggggt gcgcaccgcc gtctacacca gcggctggat
     9181 catggaaccc tggatggcgg ccgaactcgg ttcggtgttc gacgaggtga tcgtgagcct
     9241 cgacggggcg acggcccagg tccacgaccg gatccgcggc cggcgcggct ccttcgaccg
     9301 ggcgctgagc gccctcaccc tgctcgacgg ggtcgcccgg gagcgcgccc ggcgggggcg
     9361 cgcgccgctg tggttcggca tcgactgcgt cgtcgtgcgc agtaatttcc cgcaactcga
     9421 ggaattctgc acggccatcg ccccgcgctt cccggaattg cgcacgctca ccttcaacgc
     9481 ggcggtgccc gaagggctcg ccagccgccc ggaattctgc cgcttcgaac tcctcgacga
     9541 cacccaggtc gccgagttga ccagtgacgg gcggcgggcc cggctccagc ggctcgcacc
     9601 ggccggggta cgggtcttca ccaccgacaa tcagaacctc gtgatgcgcc cggatcgttt
     9661 cgccagtggc gtcgacacac tggtgatgca gatcgaaccg gacggtgatg tcagagcgct
     9721 gcccgtgtac gagggcacgg tgggaaacat tctccaggaa tcgccgctcg atctgtggca
     9781 ccggggcgtc tcccggctca gcgatccctt tgtcgtggaa acgctgtcgg cggtgcgcac
     9841 catgcaggac tgggcggcgg ccgtgcgccg catggactat cacttcggct ccccagaggt
     9901 ccgttcccgt atcgaccgcc gcgcgatccg tacgaatccc ccggagttca gcgccctcgc
     9961 ccactgaccc ccgcagtcct cgccccgaaa gggacgcgcc gtgctgacgc tcaaggacta
    10021 cgaccgcttc tgcctcgccg accccgtctt ctacgaggtg cccgagcgct acccggacga
    10081 ccacgagagg ttcgcggcgg cccgccggga gccgccgagg ggctggcagc ggggcgagtc
    10141 cggctggtgg atcaccctgc ggcccggtcc ggcggcgccc ggggcgggct ggcggatcca
    10201 tgtgtcggtg gcgctgccgg agctcgcccg ggccgtcgag atcgtctggg ggcactgcgt
    10261 ggcccacgcc ctgcccttcg acttcgtccg cagccgcgcc accgcacggg aactgtgcgg
    10321 ccaccgcgcc gaaccgctgc cgggcaaccg gctgatcacc gtccacgcgg gcgacggcgc
    10381 gacgctcacc cggagcctcg aagaactcgg cgtcctcctc gccgggctgc ccggcgcgta
    10441 cgtggcgggc gcgctgcggc acgggcccgg cccgctgtac gtcagccacg gcccgcccgg
    10501 cccggagggc ctgccccggc ccggcgaccg gaccgtcttc gccccgccgg gcggggtacc
    10561 gctgcccgag ccgctgcggg ccgacctgga ggcgctgcgc gcccggccgg cgggcggctt
    10621 cccctaccgg gccgagcggg cgctcggcag gtcccacggc ggcggcacct acctcgcggt
    10681 cgacaagcgc accggcgagc gcgtcgtcct gcgcgaggcc cggccgtacg ccgggctcga
    10741 cgagcgcggc gaggacgccg tcacccggct cgaccgggag cgggccgcgc gcgagcgcct
    10801 ggtgggcctg gactgcgtac cgcgcgtcct cggccacctc acccacgccg aacaccgctt
    10861 tctcgccgag gagttcatcg aggggacctc gctgctgcgg gccgccgccg acgccttccc
    10921 gctcacctcg cgggagcgcg ccgcgcggga ggccgccccc tacaccgcct gggccctgga
    10981 cgtcgtggac cggaccgagc gggccctgca cgccctgtac gcccacggac tgcgcctcgg
    11041 cgaactccgg ccggagaaca tcgtcgtgcg gccggacggg cgggtggcgc tcgtcgggct
    11101 cggcacgctc acggacgccg gggacgaccg ggcccccgcc accggcgacc ccggcttcgc
    11161 cgcaccgccc ggccttacgg cccccgacgc cctgcgccat ctgctggacc ggctgcgcct
    11221 gtggcttttc ctgccggtcc cccaccgcgg cccgggcaag ctccacaccc tcaccgccgc
    11281 gatcgagcgg cactacccgg tcccccgggg gttcggcgcc gggctgctga cggggctgtg
    11341 gcccgagggc cacccggccg aggacgaccg ggcgggcgcg ctgctggcgg cggaccggcc
    11401 cgactggccg gcgatccgcg actccctcgt ccggggcatc cacgccaccg ccaccccgga
    11461 ccgcgccgac cggctcttcc ccggcggccc caccgggacc ggggagctgg gcggccccgg
    11521 gctcgcccac ggcgcggccg gggtcctgta cgcgctgcac cggaccgggg cgcgggttcc
    11581 cgaggagtac accgcgtggc tcctggacgc cgtgcggcgc gaccccgagc ccgcgcccgg
    11641 cctccacgag ggccttcacg gcgtcgcgtt cgtcctcgac gcgctcggcc tgcgcgcgga
    11701 ggccctcgac gtcctcggcc tctgcccgcc ggagcgcgac gcggtgcccg acgcgggcct
    11761 ggccgccggc cgggccggca tcgccctgac cctgctccac ttcgccggcg ccaccgggga
    11821 ccccgcgctc ctgacccgcg cgctgggcct cgcgggcgag ctcggccgcg ccgtcgagga
    11881 cggccccccg cccgccccgc cgggccgccc cgccccctac gggctgctgc acggcgcgac
    11941 gggagcggcc ctgctcttcc tgcggctgta cgaacacacc ggcgacgcct ccctcctcgg
    12001 cctcgccggg cgcgccctgc gccacgacct ggtgcggctg cgcaccctcc ccgacgggat
    12061 gctcaccctc ttcgacggca cggccaacct gccgtacctc cacgggggca gcaccgggct
    12121 cgcgttcgtc ctgcgcgacc tgctgcggta ccggcccgac ccccggctgg ccgccgtgct
    12181 gacctcgctc cggctcacct gcgacgccgt gtacgtgcgc aacgcgggcc tgctgcgcgg
    12241 ccgggccggg tcggtggccg tgctcgcggc gctcggcgag ccggtgacag gcacggcgct
    12301 cggcgggcag atccgccggc tgtcctggta cgcccaggcc taccgggggc acctggcgtt
    12361 ccccgggttc cggatgctgc ggctgtcggc ggacctggcg acgggcgccg ccggtgtgct
    12421 gctcgcgctg ggctcggcgt tcggggcgac cgggcccgtg ctgcccttcc tcgacccccg
    12481 tcccgtggcc gtaccacccg cccgggaggg aggtgaacga cgtgtcggag atcctggagc
    12541 tgcaggagct ggaggaggag acccccgccc agtggccgtg tagcaacagc taccaaagca
    12601 ccctcggaca ggtctgagcc gccctcggag gacggcgagc cggccgccgc accgcacggc
    12661 gacggccggc ccgccggaat cgcgaggccc gacatggcac cggaggagca cggcatgctc
    12721 gctcaaggcc acctcgtcgc cgaccccctc ttcgtggacg cccctgagcg cgtggaggac
    12781 accgccgtcc gcttcgccca cgccgcccgc ccggccccgc cggggtggcg gcgcgccgaa
    12841 cgcgacggct gggtgatgct gcggccccgg gacgcgcggc tgccgccgca gggctggaag
    12901 atccacgtct cggcgaccgc cgaggaggcc tcccgggcgg tcgccacggt ctgggagtac
    12961 tgcgtcgcgc gcggcatcgg cttcaagttc ctgcgcagcc gcaccctgct ggccctcgtc
    13021 aacagcaagc gggccccgcg ctcggcgggc ggcaagctcg tcaccgtcta cccgcgctcc
    13081 gaggagctcc tggagcgcgc gctcgaggag ctgtccaccc tcttacgggg cgtcaagggc
    13141 ccctatatcc tcagcgatct gcgctggggc gaggggccgt tgtacctgcg ctacgggggt
    13201 ttcacgccac ggttctgctt ctccggcgac ggcgagtacg tgcccgccgt cgtccggccg
    13261 gacggcaggg cggtgcccga tgtgcgcggg gccgcgttca aggtgccgcc gtgggcgggc
    13321 gtgccgccgt tcgtcgccgg gcggatccgc gccgctcggg cggacggcgc cggtggcttc
    13381 ccctaccggg tggagaaggc cctgcggttc tccaacagcg gcggcgtcta ccgcgctctc
    13441 gcccccggca ccgggcggcg cgtggtgctg cgcgaggccc ggccgtacgc gggggtcgac
    13501 gacaacggca tggacgcggt ggcccggctg gggcgcgagc acgccgtgct ggaacgcctc
    13561 gcgggactcg gctgcgtacc acgggtgctc gcccggacgc gtcactggga acaccacttc
    13621 ctcgtcgagg agttcgtcga ggggaacggc tggaggaggc catgggccgc cgccaccccc
    13681 tcttccggcc gggcgcgagc cgcgcggagc tggccgcgta caccgactgg gcgtgcgcgg
    13741 tcgtcacccg cctcgaggag gcgatagcgg ccctccacgg gcggggcgtg gtcttcgggg
    13801 acctacagcc gggcaatgtg ctggtccggc cggacggcag cgtctgcctc gtcgacttcg
    13861 agacgtcctt cgggatggac gagaacttca ccccggcgct gggcacggcg ggcttcacgg
    13921 ctccctgggc gcgtacgggg ccggcggtcg acgcctacgc gctggactgc atgcggctcg
    13981 cggtcttctg cccgctcacc gagctgctgc gcttcgaccc gcgcaagcac gagcagttga
    14041 tccggcacgt ggaggaccgc ttccccctcc cgcccggcta cggcgagcgg ctgcgcgccg
    14101 gtctcgcccc gcccccggac cccgcgccgc cgcccgcgcc cacgtggccg ggcgcggcgg
    14161 ccgggccgac cggtacctgg gacgaggtcc tcggctccct gtgcgacgcc gtcgtgcgca
    14221 gcgccacccc ggagcgggcg gaccggctct tccccggtga cgtccggcag ttcgacgggc
    14281 agggcgcggc gctggcgtac ggcgcggcgg gcgtgctgca cgcgctgcac cgcaccgggc
    14341 acggcggcgg cgcgcgcttc gagggatacg tggactggct ggcccgggcg gccgagcggg
    14401 cggactggcc ccggccgggg ctgtacgacg ggctcgcggg cgtggcctac gtcctcgacg
    14461 agctcgggcg cccgcagcag gcgcgggcgg ccctggcccg gctggcggcg ttcgacctgc
    14521 gcggctgtgg ggcggggctg ttcggcgggc tcgccgggat cggcctggcc ttcgcccact
    14581 tcggggacct gcgggcggcg gcccggctgg cggagcggct ggcgcgcggc ctctgcgagg
    14641 acgttctcgc gccggtcccg gcggcggggc tgatgcgggg ctggtcgggg ccggccctgc
    14701 tgttcagccg gctcttcgcc gagacgggcg aggaccgctg gctgcggtgg gcggaggccg
    14761 cgctcgcccg cgacctcgcg cactgcgggg tgtccccggg ccggcacgtc catgtgcgcg
    14821 cggggcggcg ccggctgacc acgctgggcg ggggcggcgc cggtgtggcc atcgccctcc
    14881 acgagtacct gcggcaccgc gaggacccgc acttcgccgg gctgcgggac cggatccgcg
    14941 ccgggctggg agcggaactg ctgctgtcct cgggcctctt cgagggccac gccgggctgc
    15001 tctacgcgct cgtccacctc ggcggcccgg cggacgcgcg cgaggcccag ctgcgcgggc
    15061 tggggctgca cgcggtgcgg ttccaggggc ggctggcgtt cccgatggac gggttgctgc
    15121 ggctgtcgat ggacctggcg acgggcaccg ccggggtgct gctcgccgtc cacgcggcgt
    15181 tgcggggcac gacggcgggc gcgtcgctgc cgctcctgcg caccggttga gcgcgccgcg
    15241 ccggggtgcg cgcgctgtgg cgcgggcggg ccgggggtgc tgcgggagcc gggcggtgcc
    15301 gggtggttcc cgtggccggc gggggtagag agggccggaa cgcgcccgtc cgggtgcgtc
    15361 gaggcttctc gaaggggtac ggcatgttcg gaaagcgtgg catcggggtc gcgtcggtct
    15421 cactggcgct gatcgcctcc tgcctgggct gggccgctcc ggcggccggg gcccacgacg
    15481 accacggcgc ccacgggggc cacgggggcc acgggccggt cacgtgccag gggcgggaga
    15541 gcacgacgta cagtccgggc ctgacgctca cgccgcagtc ggtcggcatc cgggcggcca
    15601 ccgcgtacac ctgctccgac cgcccggggc acacgatcgc ggccaccgga tccgccaacg
    15661 gccggtcccc ggaatccact tgtctcggac tccacgcgcc cgcggggcac gaggtcctgc
    15721 ggtacgggga cggctcggtg tcggagatct cctaccccgt cggcaacgcc gagcgggtcc
    15781 tcggcgtcaa cacggtgatg ctcaagggcg tggtcgtcgc cgggcgcgac aagggcgcgg
    15841 aggcggaacg gttcgtcgag gtggcaccgg cccaggggct tccgctggcg tgcctgaccc
    15901 cggagggcgt ccggcggtcg accggtgtga cgcagctgcg catcattccg tgatccgggc
    15961 ctgacccggt cctgatccgg ccttgatccg gccttgatcc gggcggcggg cggccggcgt
    16021 tcagtggccg ccgcccgtca ccttgaagcc gcgcgggacc atgaacacgg tcagcagggt
    16081 cacggcgacg acgatgcccg ccgagacgta ggcggtggtg gtcagcgcgt ggtcgaaggc
    16141 gccccgcgcg gccgtcagca cccgccgtcc cgtgtccccg cccacctgcc gcgccacgtc
    16201 cgccgcgccg ccgacggaac cgcgcgcggt gtcgaggtcg tgcccgcgca gcggcaggtt
    16261 cgccgtccgg tccgtcatcc ggtgggagaa gacggcgccg tggatgctgc cgagcagggc
    16321 cacgcccagg ccgacgccga gctcgtaggc ggtctcggag accgcgccgg cctgcccggc
    16381 ccgttccgcc gggacggcgg agacgaggac ggacgccgag gcggtgatgg ccagcccgtc
    16441 gccgaggccg agcccggcca ggacgacggc gacgaccggg taggtggtcg gctccggggc
    16501 cagcgcgagg agcaggaacc cggcggccag ggcgcccagt ccggtggcca gcacggcgcg
    16561 caccccggcg tggtgcatca gccagggcga gctcagcgag ccgaccagca tggcaagggc
    16621 cgagggcagg gtgcgcagtc cggcctccga gggcgagtag ccgtggacgt actggagcca
    16681 cagcgagatg aggaacagcg cggccccgat ggcgagcatg gcgaggaggg tggccagcgc
    16741 tgccgcgagg aacgggccct cgcggaacag ccggacgtcc agcagcgggt cctcgagccg
    16801 tagttggtgc caggcgaaca gggcgagcag ggccacgccg aggacgaggg cgcccacgtc
    16861 cgaggggttg gggctgccct tggcgacgtg cttgatgccc caggcgaggg ccacgatgcc
    16921 gacgatcgac aggcccgcgc cgggccagtc gagacccccg gggtgcggag cgcggtactc
    16981 cggcagcagc cgcacgccca cggcgaccgt cacaacgacg accgggacgt tcacccagaa
    17041 cgccgcctgc cactcgaagt gctcgacgag gaacccgccc accagcggcc ccacacaggc
    17101 gcccgccccg gccacggcgg cccacacgcc gatggccagg gcccgttccc gggcgtcggt
    17161 gaagatgttc cggatgaggg agagcgtcga gggcatcacc atggcgccgc ccagcccgag
    17221 cagcacccgg ccaccgatca gctggaacga gctgtgcgcg gtcgcggcga ggacggaggc
    17281 gacgccgaag agcacgaagc cgacgaggaa gagccgcttg cggccccacc ggtcgccgac
    17341 cgcgccggtg gtgacgagga ggccgcccag gatcagccca tagatgtcga tgatccacaa
    17401 ctgctccagc gggccgggcc ggaggtcgtc gatcagcgag ggcagggcga cgttgaggat
    17461 ggtggcgtcc atggcgacca gcagcaggct ggcgcacagc acggccagca tcgcccagcg
    17521 gccgggggcg ggaccagttg tggagtgggg gtccccggaa gctcgcgcca tcggacgaca
    17581 acacctcacc gatctcggga acccgagcgt ccggtggccg gaaggcaccg gtcaggccag
    17641 tcgaccggat ccccggggca cacgcaaccg gagcgtcgtc cgagcccgcg aagcgctgag
    17701 ccctcggcgg gctttagtcg agcaggcccc ggcgcacggc ctcggcgacc gcggccgccc
    17761 ggtcgggcac gccgagcttc tcgtacagcc ggtgggtgac ggtcttgacg gtgctcgccg
    17821 ccagtcgcag ctcggccgcg agctggggga tgccctttcc ctcggcgaag ccgcgcagga
    17881 cctgccgctc gcgctcggag agggccgcgg cgtccccgtc ggcagccggc cggggaccgg
    17941 cctccgaggg caccggcctg ccgtcggcgg ccgccagcac cgcctcgacg aactcgggcc
    18001 gtttggcgtc cttggcgagg tacccggcgg ctccctcccg gagcgcccgg taaacgacgg
    18061 tcgcgtcggt ggccgccgac agcagcacga gccgggtcgg caggccctcc ccgacgacgg
    18121 cgtggatcac ggcgacgccg tccatcttgg gcagccggta gtcgatcagg gccacgtgcg
    18181 ggacgagctc ccggatggcg gtcagcgcgg cgacgccgtc ctcggcctcg gcccgcacgt
    18241 cgatacggcc gtcggcgcgc aggccccgga cgacgccctc gcggtaggcg gggtgctcgt
    18301 cggccaccac cacggtcact ctcgtcgcgg aatccggcac gtcgccaccg cctctcgcgc
    18361 ctctcacgcg tcttgctttc gcgcacgcgt cgtcgcgtcc gcccacgcgt tccacgatag
    18421 gcgcgcgcct agggctgcgc gggcggttcc ggggcgggcg gaggaggtgt ctcgggctcg
    18481 ccctcgccgg ggatggcgtt cttcgccgct tccttgccct tttcgatctt gtcggagtac
    18541 ttgtggccgg tcttctcgtc gatgaacgtc ccggccttgt ccaccgcttg ttcgaccttt
    18601 tcggggttct cggccgcggc ggccttcccc ttgccgacga ggcccttgag cgtgtcgatg
    18661 agcgacatgg cgttctcctc actgaatgcc gggcccacgc tggagaaggc cccgccatca
    18721 gcatgcgcac ggccggggag ggggcatgcg ggccacgggg cggactaacc cgaacgggtg
    18781 acggcgtacg gggcgcggac gatccgtgcg acgtcctccg ccacgcccgt cagccaggcc
    18841 tccgcgtcca ccgtcagcag gacgcgcgcg gcgtccacgt gcccggcgtg cagggcggcg
    18901 ccgcgcagga ggcccgacgt ggcggcgggg cgcgggggcg ggccggggat gccgggggcc
    18961 gggcgcggcg gggcgggggc gcgcagcgcc tcggccgcgc ggagggcgtc gtcggccacg
    19021 cggtcggcga ggaaggtcag ttcggcggcg gctccgggtg agagcggggt ggccccgagg
    19081 gcggcgcctt gccgcaggag catcagttcg ccgccgcgca gcatgtggta gccggccagc
    19141 atggccatct cccacggcgg gtccacggcg cgccggagga ggcgttcgcc ctggtactgg
    19201 cagtacgagg cctcggccag gagcatggcc acccggaccg ggcgcagggg gtcggcgggc
    19261 gcggggcggc cgcagaggag gtccgtgacg ccccggcacc cggcggcgcc cgcggcgagg
    19321 aagtcggcga cggcgcagcg cagttcgccc ccggcgccgc gcggccaggc gagcaggctc
    19381 gccaggacgc cgatcgcgcc gccgacgagg acgtcgacga ggcgcacggc ggacagctgc
    19441 cactgcggcg tggagagctg ggcgaacatc agcacgatga cgacggtgaa cgtcgcctgc
    19501 ccccacgcgg gaccgagcag cggggccgcg gtgaacccga cgagcaggac gacgggcagc
    19561 gcgaccgcgt agaagagcgg tacgtcgccg acggcgcgga gcgcgagggc ggcgagcagg
    19621 gccccggcgg tcgtaccggt gacggcgggg cgcagggcgg tacgggtgtc ggcggccgag
    19681 gtgcgcatga ggctgagggt ggccaggagg acccagaagc cgtgcgagag gccgagggcg
    19741 ccgaccagga gccgggcgcc tgccatggcc gtggccaccc ggagggcgtt ctggaggtgg
    19801 accgagcgga gggtcaggtg cacccgcatc cggtgccacc acagctcggg ggcgggcacg
    19861 gcggcgtacc agaacggtcc gtcgcgcccc gccccggccg tcgtggagcg ggcgcccagg
    19921 gcgatccgcg atgcctggcc ggccagccgc gcgccctcgg cggcggagcg gacgacggcg
    19981 tcgcggcgga gccgctcggg cggggcgccg gggatctcgt ccgcgcggac ggcgtcgaag
    20041 gcggcgacgg cacggcgcag cgcgtcgtcg tcggtgccgt cgttgccgtc gttgccgtcg
    20101 ttgccgtcgt tgccgtcgtt gccgtcgggg ggtggagtgc cgctggtcag gccggtggcg
    20161 acggggcgca gggcggtggc ggtgcgctcc agcagggcgg tggcggggtc gtcgggtccg
    20221 gcggggccgg gggcgccggg gccgcgacag aagcggtcga gctggtcgtg gacgtgccgg
    20281 acgcacgcgc gggtgtggtt gagggcgcga tcgcgggcgg agggcgaggt ggggcgctcg
    20341 gcgggtggga tccgggaggg acgcgcctcc tggagcgcca gctcggcggc gggccggacg
    20401 tcctcgccgc cgcgcgcggc ggcggcgcag ctgtcggcca cggcggccgt cgcgcggccg
    20461 agccgcaccc ggtacggggt gggcgggggc tcccgcaggc cgaggaggtc cagcagccgg
    20521 tcgacgaggg cggtgagcag gatgccggcg gtcaggcccg ccaggcggga gccgagggtc
    20581 tcgggagcgt agggcgggaa gcagggcagg atgtagaaga gctggcaggc cacgctcagc
    20641 ccggccgggc cgggcccggc cgtcgccgcg aaggcgacga ggaagcccac gacgaacatg
    20701 ccggccgcgg cggcccagcc gcgcacggcc agcagcgtgc cggacgtgac catgatccag
    20761 cccaccggca ccatcgcgag gaggacgcgg gtgcggtgcc gggcggggcc ggggatctgc
    20821 gagaacagca ccagcgggag gacgccgaag gtggcgtaga ggccgacggt gcggtcgccg
    20881 agggcgtgcg cgaagccgta gaagccggcg cagccggcga gggtggccca ggcggcgcgg
    20941 cgggccgcgc ctgcgggcgg ggtgcgggcc atggtgcttt cccaggctag gcggggtgcc
    21001 gcaggtcgca accgggggaa gacttgcccc ggtcccgccc tttcaccgtt tcccggggct
    21061 ccgccccgga ccccggtcct caagcgccgg acgggctgct gtgctctgtc ctcaagcgcc
    21121 ggacgggctg ctgtgctctg tcctcaagcg ccggacgggc tgaattagct ccctgccgcc
    21181 accagccgcg ccgcgacctg gtcggccgtg gcgtgtccca cggccaggac cgtgacacgc
    21241 tcgccgtcga cggcgagcag cgtcgggaag ccctggacgc cgtactccgc agcgcggcgg
    21301 aagtccgcgc gggcggcctt ggcggcgccg ggtgccgaga aggcggcggc cacggcgtcc
    21361 gcgtcgaggc cggcggcctc ggcgacggtg cggtaggtgc tctcctcgga gaggctgagc
    21421 ccgtccgcgt agaacgcgtc ctggagggcg gcggccagct cggcggcccg gtccggggcg
    21481 gcttggcgca gggcggccat gccgcgcgcg gcggcctcgg agtccatgac gaaggagccg
    21541 tccgcgatca gccggtcgta ggccgcgccg aactccgccc ccgtcagctc agcgatcttc
    21601 gcgttggcgc cctggacgta gccgaactcg cggatcggca cgcggcgggc gccggtgaac
    21661 agtccgccgg agacgacctc cacgggcagc tccgggtggc gccgggcggt ctcggtgagc
    21721 gtggccgaga agccgtggga ccagccgcag taggcgtcga agacgtagac gagcttcatg
    21781 gggggtgcct ccaggagggt gtgacgcgag ctattcacct gccacaacag tatctgctca
    21841 gtcagatatt ccggacggcc gaccgcactc ctcggcgcgg ccctcagcgc agtcgcggca
    21901 gcgcgtccct cgccgcgtgg ctgaggacct tcaggtcctc ggcgaaccgc tcccggtgcg
    21961 cctccggcag cggctccagg aagaagcggc ggatgttctc gcggtggatc cgggcggccc
    22021 ggaccgccgt ctcctccccc gccggggtca gccggacgag ccggccccgc cggtcgccgg
    22081 ggtcggcgtc ccggaccacc aggcccgccg cctccatccg gtccaccagc cgggtcaccc
    22141 cgcccgtgct cagtacccgc tcctgggcga tcgcccgcat gggcagcccc gcctccccgg
    22201 cccggcccag gatcagcagc acctcgaaca tcaggtggct gatcccgcac tcctcctcga
    22261 tcgcccggcc caggatgtac tccagccggt tcgcggcccc ctggagccgg ccgaaggcca
    22321 gcaccaggcc gtcgtccgcc gcttccctgg ccgtcgcgat cccgctctcg tgtgccacgt
    22381 ggcccctctc gcccgtcacc cgtcacccct ggctgtgcgt ggcacccgtg cgccactgga
    22441 ggagcctaga gctacgccga gaactgccgc accagccgca ccccctggac ggccgtcaag
    22501 tgcggcagat acgccttgct gaccgcccgg gtgatggcgg gcagggccgc cgggtccggg
    22561 taggccatgt acatgggccg gta
//
