LOCUS       NZ_CP034587            22247 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 737102
            Orig. end                         :: 759349
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22247
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22247
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22247
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12247](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12247
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            345..1145
                     /locus_tag="EKH77_RS02960"
                     /old_locus_tag="EKH77_02960"
     CDS             345..1145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS02960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_02960"
                     /product="hypothetical protein"
                     /protein_id="WP_126912879.1"
                     /transl_table=11
                     /translation="MADTFRNAEAEIKIILAGGTAEDARRSLGLEPGNGKRLGIHFWDA
                     PREDGEGIRLPLAEAGAIIRLRRPDRGTKGNKGGGKGDRSDLTAKLRPCDPAALPAKWR
                     ENRGGKGWEFKVEEDWSGSDRVWSASLKVDGTFEPPASGDGNGPAPWPPPLTPGQRDLL
                     AHAGITDDGLRDAVALGPVRAARWKLSRPDLARPLTAEFWSVGDDGPCFLELSLRAPHA
                     DAPGAQELLERIVREQGLRPAPQQASKTQTVMTELARNHLRGAG"
     gene            complement(1197..1664)
                     /locus_tag="EKH77_RS02965"
                     /old_locus_tag="EKH77_02965"
     CDS             complement(1197..1664)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS02965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_02965"
                     /product="hypothetical protein"
                     /protein_id="WP_126912880.1"
                     /transl_table=11
                     /translation="MGKKTATTLAAAALMAVTLGGQAGAATLDHTSSTTGATRTSASAA
                     MSTEVRNAPFVLERNQSVSSDTATLVMQSDGNLVVYDEFGRARWASNTVNSGWRAAFQE
                     DGNFVVYTRSGKAVWNSGTAGHPGSRLAVQDDGNVVIYDGSQAIWNTRTAH"
     gene            complement(1875..2072)
                     /locus_tag="EKH77_RS02970"
                     /old_locus_tag="EKH77_02970"
     CDS             complement(1875..2072)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104845.1"
                     /locus_tag="EKH77_RS02970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_02970"
                     /product="hypothetical protein"
                     /protein_id="WP_126912881.1"
                     /transl_table=11
                     /translation="MSHRRTRTRIRLALIGTFPTALAVPALALLAAFGAVPWEVLPALA
                     VALAVHAAVNFLWRRSSRTT"
     gene            complement(2069..2878)
                     /locus_tag="EKH77_RS02975"
                     /old_locus_tag="EKH77_02975"
     CDS             complement(2069..2878)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979586.1"
                     /locus_tag="EKH77_RS02975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_02975"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_126912882.1"
                     /transl_table=11
                     /translation="MTASTTWKVGPLAEASGLTVRTLHHWDTIGLLSPSRRTAGGHREY
                     TEDDLVRLYQVLALRGLGLGLDTIAACLDAGVDPGRLVRDHLAKVEASIAALDVLRQRL
                     RRLDDSLAAGQYPTTGMLLDALHALGGTGPEGEHTLRRHLDDDQLRVLETRAAALGPAA
                     HYLLEIEWPELYRRADRLRTAGVPPTDPKVRRLVTRMDELSTLFTGGDAGISTGVRAAW
                     RDDPAAMSGEPEAPADGWRELADYLDAARSDSLRPLPPSSSAEGARP"
     gene            complement(2947..4095)
                     /locus_tag="EKH77_RS02980"
                     /old_locus_tag="EKH77_02980"
     CDS             complement(2947..4095)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038286.1"
                     /locus_tag="EKH77_RS02980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_02980"
                     /product="hypothetical protein"
                     /protein_id="WP_240667194.1"
                     /transl_table=11
                     /translation="MDIGELTDETLRDLRRERPYPAVSLLLPTTRRAPTSTEDQVRLRN
                     TVAEAKRRLADDPKASRSARIDVEAQIDAAVKEVDLAHSSDGLLILAAPGEHQVWYLPR
                     TVPQRVVVSDTFLTRNLVAARLSEEPYWVLVLSEAETRLWDGAGDHLVETIANGFPVRP
                     SLPDHEDALPGANFDKVGSHATTAREEAHVERERQYTRTVVGALMPVLDREPRPLYVVG
                     LREQIALLEKLCPRPGAITSRTEQGGAIGLSAHALAEVLRPAFEERRAARQGEVLRRLS
                     DARGQKRFTSGLDEIWQTVRQGRVALLAVEDHYQITARVDGNGGHPVRLEEPAEPLTAD
                     PAIREDVVDEIVEAALDNGADVEFVRDDTLAEEDRLAAVLRY"
     misc_feature    complement(4147..4162)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.54"
                     /tool="antismash"
     gene            4307..5500
                     /locus_tag="EKH77_RS02985"
                     /old_locus_tag="EKH77_02985"
     CDS             4307..5500
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449845.1"
                     /locus_tag="EKH77_RS02985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_02985"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_126912884.1"
                     /transl_table=11
                     /translation="MTKRTARGVLLSLLTAAALIGGASGPSGARSSVPPDHRAHEGTRA
                     AMEALVRAGMPGVVGQASEGRDGSGAGDGRRVWNGSAGTADLGRPRAPRARDRFRIGSN
                     TKTFVATVMLQLEAEHRLRLTDTVERWLPGLVRGHGNDGRAVSLRRLLDHTSGISDYAA
                     DPALHKRLFERDFLRHRFDTYTPRQLVRTAVSHPPVFAPGKGWSYSNTNYVLAGLVIEK
                     VTGHPYGREIRDRVLRPLGLRATSVPGRSAALPRPSGRGYIRFPDEPGTPFHDVTGINP
                     TEAWAAGEMISTVGDLNAFYRALLGGRLLPARQLAEMLTTVDTGLRPAARYGLGIAARK
                     LSCGVTVWGHDGGIQGAVSQVSGVRDASHTAAFGGNALGVPFDTLALAEAEFCGRAR"
     gene            complement(5552..6142)
                     /locus_tag="EKH77_RS02990"
                     /old_locus_tag="EKH77_02990"
     CDS             complement(5552..6142)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS02990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_02990"
                     /product="hypothetical protein"
                     /protein_id="WP_206279799.1"
                     /transl_table=11
                     /translation="MAEIWMPHAINMDLGDHAPYDPGFPPKAIAHITADTDKATPEHPL
                     DLVPFTNLQGFFTHDGKEKAPHILWDPFAGAFAQFFPATSRSKAVHDLAGGTRTNRAGK
                     VVIQIEALFFPFCRVNGKVFRRLADTPCKGWPALNAWVRSWEVPDTWPMGHPVDFTPHR
                     SETVWETKGGWYAHAQVPENTHVDPGSWPDFAE"
     gene            complement(6235..7008)
                     /locus_tag="EKH77_RS02995"
                     /old_locus_tag="EKH77_02995"
     CDS             complement(6235..7008)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013672.4"
                     /locus_tag="EKH77_RS02995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_02995"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_126912885.1"
                     /transl_table=11
                     /translation="MFWSRRWPAVAAALLLMLAAAAPGIAAPGAVGRPGAGSVSGRPGC
                     SGAALRRVPTDRKVIALTFNAAWNEDGITRVLTVLRRERVPAMFFLTGDFADRHPEAAR
                     ALAARHPVGSHSYSHPRFPGLSFPEERREAVLSARAIRRATGRMPVAFRFPYGEFTERN
                     VRDVNALGYAVVEWVDDTAGWRGPDGGVTVDMVVRRAERAFSPGAIIQMHVGSTDARHS
                     VLDADALPRIIASARAHGYGFADLGRLVRRCRVRG"
     gene            7186..7374
                     /locus_tag="EKH77_RS03000"
                     /old_locus_tag="EKH77_03000"
     CDS             7186..7374
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS03000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_03000"
                     /product="hypothetical protein"
                     /protein_id="WP_126912886.1"
                     /transl_table=11
                     /translation="MRRTPVMTLGTAAVLGLLPGSPGTADSGAPTITACRLPAPTRPGT
                     RLRGTVPVARLTYGPAQ"
     gene            7358..9085
                     /gene="polX"
                     /locus_tag="EKH77_RS03005"
                     /old_locus_tag="EKH77_03005"
     CDS             7358..9085
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="polX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890124.1"
                     /locus_tag="EKH77_RS03005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03005"
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="WP_126912887.1"
                     /transl_table=11
                     /translation="MARPNDEVEAVLQEYADLVAITGGDAFKARAYEKAARAIGGFPTD
                     ISTLDAEGLREIPHVGKSIADKVLEYLSTGRIPALEETRAAIPPGVRELIAVPTLGPRK
                     AMTLYEELGVSSVEQLLDAIHDKKLRDLKGFGPRTEENILHGIDLARKAGGSGGRILID
                     AAMDVAEQIVAELSGTAGCEGCAYAGSLRRMRETIGDIDVLVAATRSGPFMEAIAALPY
                     TAEVIAHGEKKTSIRTTKGLQVDLRVLPPGSWGAGLLYFTGSKAHNIRIRELAVRHGYK
                     LSEYGLFHAKSGRRITSATEEDVYARLGLPWIPPTLREDRGEVAAGLRDELPELVEDGD
                     IRGDLHTHTDLTDGLASLEDMVTAAARRGYSYYAVTDHAPDLYMQRMTDAKILAQRERV
                     RELDGKHRRMRLLHGAELNIGPDGEVDWPGEFLAGFDLCVASVHSHFNQSRAELTRRLV
                     RACENPHVSVIGHPTTRLIGKRPGIDADFDAVFEACARTGTALEINAHPERIDLCDEDI
                     LRAKRYGVKFAVNTDAHSTTHLPYMRYGVGTAQRGWLTKDDIINTWPLQRLRRFLSPK"
     gene            complement(9107..9805)
                     /locus_tag="EKH77_RS03010"
                     /old_locus_tag="EKH77_03010"
     CDS             complement(9107..9805)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563157.1"
                     /locus_tag="EKH77_RS03010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03010"
                     /product="VC0807 family protein"
                     /protein_id="WP_126912888.1"
                     /transl_table=11
                     /translation="MTDVSSAPSRRFGPSAMLSWAVTIACNVVLPFVTYNQLTGAGWSD
                     FSALVASGVWPVVDVVIYLIWHRRVDEFAVLTLIFLVLTIAVTGVGPHSARLLLVKDSL
                     ITGLFGVVCLISLATPRPLMFYLGRKFGTDGSANAVAHWNGLWRHESFRRTMTLITMVW
                     GLGYVVEAIARVGLSYALSTGAMVAVNSVLAYGVPALLIAWTITHSKRARAKGHAEATA
                     PAAEAAATAV"
     misc_feature    complement(9884..9900)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.64"
                     /tool="antismash"
     misc_feature    9893..9907
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.98"
                     /tool="antismash"
     gene            10001..12247
                     /locus_tag="EKH77_RS03015"
                     /old_locus_tag="EKH77_03015"
     CDS             10001..12247
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174668.1"
                     /locus_tag="EKH77_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03015"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_126912889.1"
                     /sec_met_domain="T1TS (E-value: 2.9e-79, bitscore: 266.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNPFELPRFYTPHPARLNPHLEGARRHSKAWARRMNMVEGSGVW
                     DEGEFDSHDYALLCSYTHPDASGPKLDVVTDWYVWVFFFDDDFLARFKRTGDTVGARAY
                     LDRLRAFMPLGPDDPVAEPTNQVEAGLADLWARTVPDMSPEWRRRFRESTWHLLEESMW
                     ELSNINEGRVANPVEYIEMRRKVGGAPWSAHLVEYAAGAEVPDAVAASRPLRVLKDTFA
                     DGVHLRNDLFSYQRETESEGELANAVLVFEHFLGCDTQRAADAVGDLLTSRLQQFEHTA
                     LTEVGPVLREHGLDARAYADVFAYVKGLQDWQAGGHEWHLRSSRYMKSTTGTPRVPEAL
                     LGGPLGIGTSAALLVPSILAALPARLRGFTHVPFEKVGPLPRPDFEMPFQTRHNPHLEA
                     TRRHGVDWARRTGITVPSPTDPLAGHWDEENLHDFDLGLCAAGISPESSPDELDLATDW
                     LIWGTYADDVYPAHFGRRADGLTAAKDCTDRLKLFMPLDAVVTETPLNCLERSLADIWV
                     RTVTPMPAADRAVFRRAVEGMLDSWQWELTNQRMNKIPEPVDYIEMRRDTFGSPLTMAL
                     ARLRHGKALPPEVLASRPVQALENAASDYATLMNDVFSYQKEIEFEGEVHNSVLVVQNF
                     FDCGREEALGIVADLMRSRMREFLHIVATQLPALCEEFALDVKARIALDGYVQELKDWL
                     AAILTWHRECRRYGEADLVRRRAASAAAPPLQAPLGAPAGLGTSGTRLTSLLRG"
     tRNA            complement(12307..12380)
                     /anticodon=(pos:complement(749446..749448),aa:Lys,seq:ctt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EKH77_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EKH77_03020"
                     /product="tRNA-Lys"
     gene            complement(12307..12380)
                     /locus_tag="EKH77_RS03020"
                     /old_locus_tag="EKH77_03020"
     misc_feature    12494..12511
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.94"
                     /tool="antismash"
     gene            12500..13630
                     /locus_tag="EKH77_RS03025"
                     /old_locus_tag="EKH77_03025"
     CDS             12500..13630
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240822.1"
                     /locus_tag="EKH77_RS03025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03025"
                     /product="dispase autolysis-inducing protein"
                     /protein_id="WP_126912890.1"
                     /transl_table=11
                     /translation="MQRIGIAATAAAAALALVQMPASAQPPTTAADGPASWTAPSCARV
                     TGDGSVTFTTDDGRTLAPTSGTLKATGYTHGLVALDTPGTLLATHNDALLRSTDAGCVW
                     QRVATLGGASTRLAAAPGGRAFVWQKNGRYLARVDGTTVTPLKAPTARVSGLGTDRARP
                     GHVRLAGADGQLYDSVDGGATWRRAGTPAFGGTASVYGVAFDPADPDHAVAGGMATGGA
                     VTTDGGVTWRAARGLSADGGRANLFDAAVSPADPHVVYALGVDLVEAAPGSSSEGRHLY
                     RSADGGLTYAKVVDDSAAVKLTNGTLLAPSPVDPKVLHFTFGTYFQNYGTDLFRYDAST
                     GRVTATHNAYDGVSAIAFNPARPEVMYLGVEEVRVD"
     gene            complement(13654..15447)
                     /locus_tag="EKH77_RS32890"
     CDS             complement(13654..15447)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04215.1"
                     /locus_tag="EKH77_RS32890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="choice-of-anchor A family protein"
                     /protein_id="WP_164737724.1"
                     /transl_table=11
                     /translation="MNEGTARPPDDPRTRFRARCTTWLRRTAAGAATAAAALGGLALPA
                     QAAPLPGGLGPCLPGSCPRTYPALNDRPFTGRDDNINLFTGGDFRVRGGAAGAEGRVVT
                     LGDFDVNKTSGGPLYTVGVLHFGSRVPPSDGADFLTTDGDVLVAPGQRLDAERGVVRHA
                     GDVSGLVIGGDVAASGAARPYAGLRERLLAAGRCYARGADGRGRPATGTARNTGTETVF
                     TGDGTSRLQVFHVNFDLVGRDGGQQAIRFTGIPAGATVLVNLEGTSRVVNTFSGGATDD
                     NPFNRLRERLLWNVPDARRVDFLGTGQFQGSVLVGDPTSEATVTLPGMNGRFLTAGSLT
                     HTSATGGGSGQEFHAYPFNGDLPDCAPPPRPTGEVTVVDRDAQDGRPLQGARFQLWRET
                     NGVPGLQTSGDRPDTRSADECVSDTHGVCRTTVEPGTYYWQELQPPPGYKLPDRTVFGP
                     LELTAVNAAEGVSLTVGSTPDPASYGSIHLVTKDARTGRPLPGARFELWRETNRRPGLQ
                     IAGAAPDRRADPGCTTDRAGRCAFRGLPPGAYYLRETVVPDGYLPPPERVFGPYAVTVA
                     NARSGITVTVKGTPREKGGRA"
     misc_feature    15510..15525
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    15517..15531
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.31"
                     /tool="antismash"
     gene            complement(15590..15916)
                     /locus_tag="EKH77_RS03035"
                     /old_locus_tag="EKH77_03035"
     CDS             complement(15590..15916)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742334.1"
                     /locus_tag="EKH77_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03035"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_126912891.1"
                     /transl_table=11
                     /translation="MIFIAVKFTIRPERSAEWLDLVKDFTEATRAEDGNVFYEWSKSVD
                     NPHQFVLLEAFKDSAAGETHVNTEHFKTAMAWMPDVVASTPEIIHVETPGTGWSAMAEV
                     TPRP"
     misc_feature    15897..15910
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    15993..16008
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            complement(16053..16967)
                     /locus_tag="EKH77_RS03040"
                     /old_locus_tag="EKH77_03040"
     CDS             complement(16053..16967)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540969.1"
                     /locus_tag="EKH77_RS03040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03040"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_126912892.1"
                     /transl_table=11
                     /translation="MIDPRRLRVLSALADHGTVTAAAHALYLSPSAVSQQLAALEAETG
                     HALLERRGRTVRLTAAGSVLAGHAVEIAAQLERAEADLARCSTGLVGEVTVAAFATSIT
                     EVVAPAVAALGRRAPQVRVRVKDAEGHTSARLLLDGEADIAVAVEHRDALASDAGRLLH
                     APLYEEPFDAVLPPGHRLADKPEVDLTDLRDDPWITPWPGNPVHEAVVRACEEARFRPR
                     VECLSDDFSAVCALVAVGAGVALVPRSALHGIRPALTPAVRPLRGPGPTRRVFTAVRRG
                     SEGHPLLRLALAELRDRAAALVG"
     misc_feature    17005..17021
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(17055..17071)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.62"
                     /tool="antismash"
     gene            17062..18102
                     /gene="tdh"
                     /locus_tag="EKH77_RS03045"
                     /old_locus_tag="EKH77_03045"
     CDS             17062..18102
                     /EC_number="1.1.1.103"
                     /GO_function="GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (12-266). E-value: 7.1e-11.
                     Score: 33.7. Matches aSDomain:
                     nrpspksdomains_EKH77_RS03045_PKS_ER.1"
                     /codon_start=1
                     /gene="tdh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016467934.1"
                     /locus_tag="EKH77_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03045"
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="WP_126912893.1"
                     /sec_met_domain="ADH_N (E-value: 3.2e-30, bitscore: 102.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.6e-23, bitscore:
                     79.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALVKTAAGPGLELTEVPTPEAGPGQVLIKVLRTGICGTDLHID
                     SWDDWAARVVRAPLVVGHEFAGEVVETGAGVSTVSVGDIVSGEGHLVCGTCRNCMAGRR
                     HLCIRTIGLGVHTDGAFAEYVVLPESNVWVHRHEIDIDVAAIFDPFGNAVHTALSFPVL
                     NEDVLITGAGPIGMMAAAVANHAGARSTVITDVSPYRLALAEKMGATVALDVSDRRIAD
                     VMPELGMTEGFDVGMEMSGRADALQDMIATMSPGGRIAALGLPTGDVSIDMATVVTRML
                     TLRGIYGREMFETWYAMSVLLRSGLDISPVITHRFGFEQYAEAFATARSGQCGKIVLDW
                     TRPVLP"
     aSDomain        17098..17859
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS03045_PKS_ER.1"
                     /evalue="7.10E-11"
                     /label="EKH77_RS03045_PKS_ER.1"
                     /locus_tag="EKH77_RS03045"
                     /protein_end="266"
                     /protein_start="12"
                     /score="33.7"
                     /tool="antismash"
                     /translation="LELTEVPTPEAGPGQVLIKVLRTGICGTDLHIDSWDDWAARVVRA
                     PLVVGHEFAGEVVETGAGVSTVSVGDIVSGEGHLVCGTCRNCMAGRRHLCIRTIGLGVH
                     TDGAFAEYVVLPESNVWVHRHEIDIDVAAIFDPFGNAVHTALSFPVLNEDVLITGAGPI
                     GMMAAAVANHAGARSTVITDVSPYRLALAEKMGATVALDVSDRRIADVMPELGMTEGFD
                     VGMEMSGRADALQDMIATMSPGGRIAALGLPT"
     gene            18165..19349
                     /locus_tag="EKH77_RS03050"
                     /old_locus_tag="EKH77_03050"
     CDS             18165..19349
                     /EC_number="2.3.1.29"
                     /GO_function="GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (41-383). E-value:
                     1.3e-71. Score: 233.6. Matches aSDomain:
                     nrpspksdomains_EKH77_RS03050_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356659.1"
                     /locus_tag="EKH77_RS03050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03050"
                     /product="glycine C-acetyltransferase"
                     /protein_id="WP_206279800.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.2e-69, bitscore:
                     233.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-05, bitscore:
                     22.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDSMREHLRKELQDIRDAGLYKSERVITSPQSAAISVGDGKVLN
                     FCANNYLDLADHPEVIAAAKTALDDWGFGMASVRFICGTQAPHKELEEKISRFLGMEDT
                     ILYSSCFDANGGVFETLLTAEDAVISDELNHASIIDGIRLSKAARFRYRNRDMADLERC
                     LKEASGARHKLIVTDGVFSMDGYIAPLDEICDLAERYGALVMVDDSHAVGFVGEEGRGT
                     PELFGVTERVDIITGTLGKALGGASGGYVAARAEIVELLRQRSRPYLFSNSLAPSIVGA
                     SLRVLDLLTESGDRRARLRENTKLFRAEMTAAGFDILPGEHPIAPVMVGDAALAGRMAA
                     ALLEKGIYVIAFSYPVVPNGKARIRVQLSAAHSREDVLRTVAAFREVRDALVAA"
     aSDomain        18288..19313
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS03050_Aminotran_1_2.1"
                     /evalue="1.30E-71"
                     /label="EKH77_RS03050_Aminotran_1_2.1"
                     /locus_tag="EKH77_RS03050"
                     /protein_end="383"
                     /protein_start="41"
                     /score="233.6"
                     /tool="antismash"
                     /translation="KVLNFCANNYLDLADHPEVIAAAKTALDDWGFGMASVRFICGTQA
                     PHKELEEKISRFLGMEDTILYSSCFDANGGVFETLLTAEDAVISDELNHASIIDGIRLS
                     KAARFRYRNRDMADLERCLKEASGARHKLIVTDGVFSMDGYIAPLDEICDLAERYGALV
                     MVDDSHAVGFVGEEGRGTPELFGVTERVDIITGTLGKALGGASGGYVAARAEIVELLRQ
                     RSRPYLFSNSLAPSIVGASLRVLDLLTESGDRRARLRENTKLFRAEMTAAGFDILPGEH
                     PIAPVMVGDAALAGRMAAALLEKGIYVIAFSYPVVPNGKARIRVQLSAAHSREDVLRTV
                     AA"
     gene            complement(19411..19962)
                     /locus_tag="EKH77_RS03055"
                     /old_locus_tag="EKH77_03055"
     CDS             complement(19411..19962)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676809.1"
                     /locus_tag="EKH77_RS03055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03055"
                     /product="heme-binding protein"
                     /protein_id="WP_126912894.1"
                     /transl_table=11
                     /translation="MKSLQNVSVRARVIAGSVAVAVAGAVTFGAVAATAAPVPAAAPAP
                     VAKGLVQVNRLSVDAATKAAQAALAAAKKDGQKVSVAVVDRDGNTVVTLRGDGAGPQSY
                     ESAERKAFTAVSWNAPTSELVKRLQQTPNLKDIPGTLFLPGGAPVQDKGAPVAGIGVAG
                     APSGDLDEKYAKAGVAGLAE"
     gene            20133..21350
                     /locus_tag="EKH77_RS03060"
                     /old_locus_tag="EKH77_03060"
     CDS             20133..21350
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154871.1"
                     /locus_tag="EKH77_RS03060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03060"
                     /product="sensor histidine kinase"
                     /protein_id="WP_240667195.1"
                     /transl_table=11
                     /translation="MNTYVTGTAPPLPDRDPDARWFAVVRHTAFFLLLGASLVRFLIRH
                     AGHPDTPWIIALSTLLGILYVLGAGLDDAAPAHRRLWLGAVVGVWVVLVVAAPSFAWCA
                     VPLVYTALRTLPVRGSLVLIAGLTVFVVAAQISLFGFDPNLVVAPPTVAALATAAFVHM
                     ERQRARQDALIGDLLRTRRELAATERREGALAERQRLSMEIHDTLAQGLSSQQMLLQAA
                     DRIWTADPGTARHHVRAAADVAARGLAEARRFVQDLAPADLAGGVPLAEALRALAEREP
                     VPGLAVRFHQEGTPVPLPESAESALLRIAQGALANVREHAGASTAALTLTWLDDQVVLD
                     VADDGRGFDASTAPAAGPGRGHGLPAMRARAGRLGGRLSVESVPGEGTVVSAALPLVSP
                     DSPELP"
     gene            21347..21991
                     /locus_tag="EKH77_RS03065"
                     /old_locus_tag="EKH77_03065"
     CDS             21347..21991
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887434.1"
                     /locus_tag="EKH77_RS03065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_03065"
                     /product="response regulator transcription factor"
                     /protein_id="WP_126912896.1"
                     /transl_table=11
                     /translation="MSAATPVRLLLCDDHAVVRAGLRALFASEPGIEVVGEAGTGEEAV
                     AMAAKLRPDVVLMDLQLGPGIGGVEATRRITAAPDEVRVLVLTTYDTDADVTRALEAGA
                     TGYLLKAERPEELFAAVRAAAQGRTALSPPVAGRVMARLRGTRPATGTLTDRERDILDQ
                     LARGLGNRDIARALFISEATVKTHLGRIYAKLGVDTRAGAVAVAKEQRLLG"
     misc_feature    complement(22220..22235)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.5"
                     /tool="antismash"
ORIGIN
        1 ccgacacgta ctcgccggcg gccatcgaga gcgaaccggc cagcagtccc gccagtccgg
       61 cggtcagcag ggtgccccga tcctcggtcg cgccggcgac gccgacgacg agtccggcgg
      121 tggacaccac tccgtcgttg gcgccgagga cggcggcacg cagccagttg agccgcgctt
      181 cggtggcctg gacgggcccg acgtggtgcg gcgggtcatg atcgctcacg gggcaaggat
      241 cccgtcgggc cgggcggggc cggtgcgcgg cgcgccggag cccgaagttc ctgtgattgt
      301 cagccagttg gcgcgcattc tccctctgtg acataaagga tgacatggcg gatacgttca
      361 ggaacgccga ggccgaaatc aagatcatcc ttgcgggtgg gacggcggag gacgcgcgcc
      421 ggtctctggg gctggagccc gggaacggca aacgcctcgg catccacttc tgggacgccc
      481 cccgggagga cggcgagggc atccgcctcc ccctggcgga ggccggggcc atcatccggc
      541 tgcgcaggcc ggacaggggc accaagggaa acaagggcgg cggcaaggga gacaggagcg
      601 atctcacggc gaagctgcgg ccgtgcgacc cggccgccct gcccgcgaaa tggcgcgaga
      661 accgcggcgg caaggggtgg gagttcaagg tcgaggagga ctggagcggc agcgaccgcg
      721 tctggtcggc ctcgctcaag gtggacggga ccttcgagcc gcccgcctcc ggcgacggga
      781 acgggcccgc cccctggccg cccccgctca cccccggcca gcgcgacctg ctggcgcacg
      841 ccgggatcac cgacgacggc ctgcgggacg ccgtcgccct cggcccggta cgggccgcca
      901 ggtggaagct ctcgcggccg gacctggccc ggccgctcac cgccgagttc tggagcgtcg
      961 gcgacgacgg cccgtgcttc ctcgaactgt ccctgcgcgc cccgcacgcc gacgccccgg
     1021 gcgcccagga gctcctggag cgcatcgtgc gggagcaggg cctccggccc gctccacagc
     1081 aggcgtcgaa gacccagacg gtcatgaccg agctcgcccg gaaccacctg cgcggggcgg
     1141 gatgacacat ccggcggccg cgaggcgacc gccggaccga tctcttcggc ggcccgtcag
     1201 tgagccgtgc gggtgttcca gatcgcctgg ctgccgtcgt agatcacgac attgccgtcg
     1261 tcctggacgg ccaggcgcga gccggggtgc ccggcggtgc ccgagttcca gacggccttg
     1321 cccgagcggg tgtagaccac gaagttgccg tcctcctgga acgccgcccg ccagccgctg
     1381 ttgacggtgt tggaggccca gcgggcccgg ccgaactcgt cgtagacgac gaggttgccg
     1441 tcggactgca tgaccagcgt ggcggtgtcg gacgacaccg actggtttct ctcgaggacg
     1501 aacggcgcgt tgcgaacttc tgtcgacatg gctgcggatg cgctcgtccg ggtcgcgccg
     1561 gtcgtcgagg aggtgtgatc gagggtggcc gcgccggcct ggccgccgag ggtgacggcc
     1621 atcagtgccg cggccgcgag cgtcgttgcg gtcttcttcc ccacgaaagg atcccttcgt
     1681 cgagttgctc ttccaccggt gcccccgggt gaaggcgggc ggaaacgaac tctcgcagct
     1741 tccccggtca cggaggaccg ctcggttccc gtatgacggg ttcacaccga cctttggcca
     1801 aggaactcgc gttcgatgcg tttccgccgg tgaaaacccg cgcgtttggc gggaacaaga
     1861 ccggtacggt cctctcatgt ggtcctgctg gagcggcgcc acaggaagtt gacggcggcg
     1921 tggacggcga gcgccaccgc cagggccggg aggacctccc agggcaccgc gccgaacgcc
     1981 gccagcaggg ccagggccgg gacggccagc gcggtgggga acgtcccgat cagtgcgagg
     2041 cggatacggg tacgggtacg gcggtggctc acggccgggc tccttcggcg gaagaggacg
     2101 ggggaagagg gcggagggaa tcggaacggg cggcgtccag gtagtcggcc agttcccgcc
     2161 agccgtcggc cggagcctcc ggctcaccgg acatcgcggc cgggtcgtca cgccacgccg
     2221 cccgcacgcc ggtggagatc cccgcgtcgc cgccggtgaa cagcgtgctc agctcgtcca
     2281 tgcgcgtcac caggcgccgg accttcggat cggtgggcgg gaccccggcc gtacggagcc
     2341 ggtcggcccg gcggtagagc tccggccatt cgatctccag cagatagtgc gccgcgggtc
     2401 ccagggcggc ggcgcgcgtc tccagcaccc gcagctggtc gtcgtccagg tggcggcgca
     2461 gcgtgtgctc gccctccggg ccggtgccgc cgagggcgtg cagcgcgtcg agcagcatgc
     2521 cggtggtcgg gtactggccg gccgcgaggc tgtcgtcgag gcggcgcagc cgttgccgca
     2581 gcacgtcgag cgcggcgatg gaggcctcga ccttcgccag gtggtcccgg accagccgcc
     2641 cggggtccac tccggcgtcg aggcaggcgg cgatggtgtc caggcccagc cccaggccgc
     2701 gcagggcgag cacctggtag agccggacga ggtcgtcctc ggtgtactcc ctgtgcccgc
     2761 cggcggtgcg ccgggagggg ctgagcaggc cgatggtgtc ccaatggtgc agcgtacgga
     2821 cggtcagccc gctggcctcg gcgagcggac cgaccttcca ggtcgtggaa gcggtcatgg
     2881 ggacaacgat gcatcctcac gccgcgtgag gttcaagccg ggacggcgat caggcgaccg
     2941 gtacggctag tagcgcagca ccgccgccag ccggtcctcc tcggcgaggg tgtcgtcccg
     3001 gacgaactcg acgtccgccc cgttgtccag cgccgcctcg acgatctcgt cgacgacgtc
     3061 ctcgcggatg gcggggtccg ccgtcagcgg ctcggcgggc tcctccaggc gcaccgggtg
     3121 gccgccgttg ccgtcgacgc gggcggtgat ctggtagtgg tcctcgaccg cgaggagcgc
     3181 cacccggccc tggcggacgg tctgccagat ctcgtccagt ccggaggtga agcgcttctg
     3241 gccgcgcgcg tcgctgaggc ggcgcagcac ctccccctgc cgtgcggcgc ggcgctcctc
     3301 gaacgccggg cgcagcacct cggccagcgc gtgcgcggac aggccgatcg cgccgccctg
     3361 ctcggtccgg gaggtgatcg cgccgggcct ggggcacagc ttctcgagga gggcgatctg
     3421 ctcgcgcagc cccacgacgt acaacggccg gggttcgcgg tccagtacgg gcatgagggc
     3481 cccgacgacg gtgcgcgtgt actggcgttc gcgctccacg tgggcctcct cgcgcgcggt
     3541 cgtggcgtgg ctgccgacct tgtcgaagtt ggcgccgggc agggcgtcct cgtggtcggg
     3601 gagggagggg cggacgggga agccgttggc gatggtctcc acgaggtggt ccccggcgcc
     3661 gtcccacagc cgggtctcgg cctcggagag caccagcacc cagtacggct cctcggagag
     3721 ccgggccgcg accaggttgc gggtgaggaa ggtatccgag acgacgacgc gctgcggcac
     3781 ggtgcggggc aggtaccaga cctggtgctc gcccggcgcg gccaggatga gcaggccgtc
     3841 gctggagtgg gcgaggtcga cctccttgac cgccgcgtcg atctgcgcct cgacgtcgat
     3901 gcgcgccgag cggctcgcct tcgggtcgtc ggcgagccgt cgcttggcct ccgcgaccgt
     3961 gttgcgcagc ctgacctggt cctcggtgct ggtcggggca cggcgcgtgg tcggcaggag
     4021 cagtgacacg gccgggtacg ggcgctcacg gcgcaggtcg cggagcgtct cgtcggtcag
     4081 ctcgccgatg tccatcaagg tcctcctcgg gcctgcgggg tgtcttccag ctcaccagag
     4141 gcatggccga acggccaatc gagcgggtcc acccggtgca cgggcgccgt gcgcctaccc
     4201 gtgcggggcc ctcccacacg tcctacccgt ctacccgtcc tactcgtacg gatgacttcc
     4261 cccgctcgtc cgacggccgg atcgtgggtc gcggtagcga agagtcatga cgaagcgcac
     4321 cgcccgcggc gttctgctgt ccctgctcac cgccgcggcg ctgatcggcg gcgcgtccgg
     4381 cccgtccggt gcccgctcgt ccgtcccgcc ggaccaccgt gcgcacgagg ggacccgggc
     4441 ggccatggag gcgctggtac gggccgggat gcccggcgtc gtcggccagg cgagcgaggg
     4501 gcgcgacggg agcggcgccg gcgacgggcg ccgcgtctgg aacgggtccg ccgggacggc
     4561 cgatctcggg cggccacggg caccgcgggc gcgcgaccgg ttccggatcg gcagcaacac
     4621 caagacgttc gtcgccaccg tgatgctcca gctggaggcc gagcaccggc tccggctcac
     4681 ggacaccgtc gagcgctggc tgccgggcct ggtgcgcggc cacggcaatg acgggcgcgc
     4741 cgtgtccctg cgccggctcc tcgaccacac cagcgggatc tccgactacg cggcggaccc
     4801 cgccctccac aagcggctct tcgagcggga cttcctccgc caccgcttcg acacctacac
     4861 gccacggcag ttggtgcgca cggccgtgtc ccatccgccg gtcttcgcgc ccggcaaggg
     4921 ctggagctac tccaacacca actatgtgct ggccgggttg gtcatcgaga aggtcaccgg
     4981 ccacccctac ggccgggaga tccgcgaccg tgtcctgcgg cccctgggcc tgcgcgccac
     5041 ctccgtaccg ggccggtcgg ccgccctccc ccggccctcc ggacgcggct acatccgctt
     5101 cccggacgag ccgggtacgc cgttccacga cgtcaccggc atcaacccga cggaggcgtg
     5161 ggccgccggc gagatgatct ccaccgtcgg cgacctgaac gccttctacc gggcgctgct
     5221 gggcggccgg ctcctgcccg cccgccagct cgcggagatg ctgaccacgg tggacaccgg
     5281 gctgcgcccg gcggcgcggt acgggctcgg catcgccgcg cggaagctgt cctgcggggt
     5341 gacggtgtgg gggcacgacg gcgggatcca gggcgcggtc tcccaggtga gcggcgtccg
     5401 ggacgcctcg cacacggccg cgttcggcgg caacgccctc ggggtgccct tcgacacgct
     5461 cgccctggcg gaggccgagt tctgcgggag ggcgcggtag cgcctcgcgc gtcccgggtg
     5521 ggattccatg aggcggtcgc ggtcagcgga gctattccgc gaagtccggc caggagccgg
     5581 gatccacatg ggtgttctcg ggtacctgtg cgtgggcgta ccagccgccc ttggtctccc
     5641 acaccgtttc ggagcggtgg ggggtgaaat ccacggggtg ccccatgggc caggtgtccg
     5701 gcacctccca ggaacgcacc cacgcgttga gtgccggcca ccctttgcac ggggtgtcgg
     5761 ccaatcgccg gaacaccttg ccgttgacgc ggcagaacgg gaagaacagc gcctcgatct
     5821 gaatgacgac ctttcccgca cggttggttc gcgtgccgcc cgcgaggtcg tgcaccgcct
     5881 tgctccggga cgtcgcgggg aagaactggg cgaaggcgcc ggcgaacggg tcccagagga
     5941 tgtgcggcgc cttttccttc ccgtcgtggg tgaagaaacc ctggagattg gtgaagggaa
     6001 caaggtccag cggatgctcc ggcgtggcct tgtcagtgtc cgccgtgatg tgcgcgatgg
     6061 ctttcggcgg aaaacccgga tcgtaaggag cgtggtcacc gaggtccatg ttgatggcgt
     6121 gcggcatcca tatctcggcc atgatccgcc tcctgccgtc atgtggtgtt cttcaagagt
     6181 gatcccgtgt gcgcggtccg gccactggtg ggcggaccgc ctgtgccggg cgtctcagcc
     6241 gcgcacgcgg cagcgccgta cgagccgtcc cagatcggcg aagccgtagc cgtgggcgcg
     6301 ggccgaggcg atgatccgcg gcagggcgtc ggcgtccagc acggagtggc gcgcgtccgt
     6361 ggagcccacg tgcatctgga tgatcgcccc cggtgagaac gcccgctccg cccgccggac
     6421 gaccatgtcc accgtcacgc ccccgtcggg cccgcgccag ccggccgtgt cgtccaccca
     6481 ctcgacgacg gcgtacccga gcgcgttgac gtcgcgaacg ttccgctcgg tgaactcgcc
     6541 gtacgggaac cggaaggcca cgggcatacg gcccgtggcc cggcggatgg cgcgtgcgga
     6601 caggacggcc tcccggcgct cctcggggaa ggacaggccg gggaaccggg ggtggctgta
     6661 ggagtggctg cccacggggt ggcgggcggc cagcgcgcgg gccgcctcgg ggtggcggtc
     6721 ggcgaagtcc cccgtcagga agaacatggc gggcacccgc tcccggcgga gcacggtcag
     6781 gacgcgggtg atgccgtcct cgttccacgc cgcgttgaag gtcagcgcga tgaccttccg
     6841 gtccgtgggg acgcgccgga gcgcggcccc ggaacagccc ggccgcccgg aaacggaacc
     6901 ggcgcctggc cggcccaccg cgcccggagc cgcgataccc ggagccgcgg cggcgagcat
     6961 cagcaggagg gcggccgcga ccgctggcca ccgacgggac cagaacatac gcacactcct
     7021 cccgcgcgaa acccgggacg atctcacgcg atccggtgcc gtccgctcgc acgccgtgcc
     7081 gatagatcgt ttctccttcc cccgtacggg cgatacggcg cgtgccgtcc cggcaccggg
     7141 gcagacccct aacgtccaag ccgatgaccg gataagaggt acttcatgcg ccgcacccct
     7201 gtcatgaccc ttggcaccgc cgccgtgctc ggcctcctgc ccggctcgcc cgggaccgcc
     7261 gacagcggcg cccccaccat caccgcgtgc cggctccccg cccccacacg gccgggcacc
     7321 cggttgcgcg gcaccgtccc ggtggcacgc ttgacctatg gcccggccca atgacgaggt
     7381 cgaagcggtc ctccaggagt acgccgacct cgtcgcgatc accggtggcg acgccttcaa
     7441 ggcccgtgcc tacgagaagg ccgcccgcgc gatcggcggc ttccccaccg acatctccac
     7501 cctcgacgcc gagggcctgc gcgaaatccc ccatgtgggg aagtccatcg ccgacaaggt
     7561 cctggagtat ctgagcaccg gccgcatccc ggcactggag gagaccaggg cggcgatccc
     7621 gcccggggtc cgcgagctca tcgccgtccc gacgctgggc cccaggaagg ccatgacgct
     7681 ctacgaggag ctgggcgtct cctccgtgga acaactcctc gacgccatcc acgacaagaa
     7741 gctgcgcgac ctcaagggct tcgggccccg gaccgaggag aacatcctcc acggcatcga
     7801 cctcgcgcgg aaggcgggcg gctccggcgg ccgcatcctc atcgacgccg ccatggacgt
     7861 cgcggaacag atcgtcgccg agctctcggg gacggccggc tgcgaggggt gcgcgtacgc
     7921 cgggtcgctg cgccggatgc gggagaccat cggggacatc gacgtcctcg tcgccgccac
     7981 ccgctcgggc ccgttcatgg aggcgatcgc cgccctcccg tacaccgccg aggtcatcgc
     8041 gcacggcgag aagaagacct cgatccgcac cacgaagggt ctccaggtcg acctgcgcgt
     8101 cctgccgccc ggctcctggg gggcggggct gctgtacttc accggctcca aggcgcacaa
     8161 catccgcatc cgtgaactcg ccgtccgcca cgggtacaag ctgtccgagt acgggctgtt
     8221 ccacgccaag agcgggcggc ggatcacctc ggcgacggag gaggacgtct acgcccggct
     8281 gggcctgccc tggatcccgc ccaccctgcg cgaggaccgg ggcgaggtgg cggccgggct
     8341 ccgcgacgag ctgcccgaac tcgtcgagga cggcgacatc cggggcgacc tccacaccca
     8401 caccgacctc acggacgggc tggcctccct ggaggacatg gtcaccgccg ccgcccggcg
     8461 cggctactcc tactacgccg tcaccgacca cgcgcccgac ctgtacatgc agcggatgac
     8521 cgacgccaag atcctcgcgc agcgcgagcg ggtgcgggaa ctcgacggga agcaccggcg
     8581 gatgcggctg ctgcacggcg ccgagctgaa catcgggccg gacggggagg tggactggcc
     8641 cggcgagttc ctcgcggggt tcgacctgtg cgtcgcgtcc gtccactcgc acttcaacca
     8701 gagccgggcg gagctgaccc gacggctggt gcgggcctgc gagaaccccc atgtgtcggt
     8761 catcgggcac cccaccaccc ggctcatcgg caaacggccg ggaatcgacg ccgacttcga
     8821 cgccgtattc gaggcgtgcg cgcggaccgg caccgccctg gagatcaacg cccatccgga
     8881 gcggatcgat ctgtgcgacg aggacattct gcgggcgaaa cggtacgggg tgaagttcgc
     8941 ggtgaacacg gacgcgcact ccaccacgca tcttccgtat atgcgctatg gcgtgggaac
     9001 ggcgcagcgt ggctggctga ccaaggatga catcatcaac acctggccgc tgcaacggct
     9061 gcgccgtttc ctgtccccga aatgacgggg actcggcagg tcaggatcag acggccgtgg
     9121 cggcggcctc ggccgccggc gctgtggcct cggcgtggcc cttggcgcgg gcgcgcttgg
     9181 aatgggtgat cgtccaggcg atcagcaggg cggggacgcc ataggcgagg acggaattca
     9241 cggcgaccat ggcgccggtc gacagcgcgt aggacagtcc gacgcgggcg atcgcctcga
     9301 cgacgtatcc gaggccccag accatggtga tcagggtcat cgtccgccgg aaactctcgt
     9361 gccgccagag gccgttccag tgggcgacgg cgttcgcgga gccgtcggtg ccgaatttcc
     9421 ggccgaggta gaacatcagc gggcgaggag tggccaggct gatcaggcag acgacgccga
     9481 agaggccggt gatcagggag tccttgacca gcagcaggcg ggccgagtgc ggtccgacgc
     9541 cggtgacggc gatggtcagc accaggaaga tcagggtcag tacggcgaac tcgtcgacgc
     9601 gccggtgcca gatcaggtag atgacgacgt ccaccaccgg ccagacgccg gaggccacaa
     9661 gggcggagaa gtcgctccag ccggcgccgg tgagctggtt gtaggtgacg aacggcagca
     9721 ccacattgca ggctatggtc acggcccagc tcagcatggc actgggcccg aagcgccggg
     9781 acggcgcgga tgacacgtcg gtcatcgatt cccccaagat caaaagagca aaacgggggg
     9841 actgtagggg aaaggcgtca ccagcagcaa gatcgttaat ctcagcccct cttttattca
     9901 ccatattggg cggaaatcct actttccctc acctcctcgc ccactccccg ccatagcgtg
     9961 cccccgacgg tcccatccac accgaaaggc cgcgcacgcg atgcccaacc ccttcgagct
    10021 gccccgcttc tacacaccgc acccggcccg tctcaatccc catctcgagg gtgcgcggcg
    10081 gcattcgaag gcatgggcgc ggcggatgaa catggtcgag ggatcgggcg tctgggacga
    10141 gggggaattc gactcccacg actacgcgct gctgtgctcc tacacccacc ccgacgcctc
    10201 cggccccaag ctggacgtgg tcaccgactg gtacgtgtgg gtgttcttct tcgacgacga
    10261 cttcctggcc cggttcaagc gcacgggcga caccgtgggc gcccgcgcgt atctcgaccg
    10321 cctccgcgcc tttatgccgc tcggcccgga cgaccccgtg gcggagccca ccaatcaggt
    10381 ggaggcgggg ctggccgacc tgtgggcgcg tacggtgccg gacatgtcgc cggagtggcg
    10441 gcggcgcttc cgggagagca cctggcatct gctcgaggag tcgatgtggg agctgtcgaa
    10501 catcaacgag ggccgggtcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtcgg
    10561 cggggcgccc tggtccgccc acctcgtcga gtacgcggcg ggcgccgagg tgcccgacgc
    10621 ggtggcggcg agccggccgc tgcgcgtcct gaaggacacc ttcgccgacg gggtccacct
    10681 gcgcaacgac ctcttctcct accagcgcga gaccgagagc gagggcgaac tcgccaacgc
    10741 cgtcctcgtc ttcgagcact tcctgggctg cgacacccaa cgggccgccg acgccgtggg
    10801 cgacctcctc acctcccgcc tccagcagtt cgagcacacc gccctcaccg aggtcggccc
    10861 ggtcctgcgg gagcacgggc tggacgcgcg ggcgtacgcc gacgtcttcg cctacgtcaa
    10921 gggcctccag gactggcaag ccggcggcca cgagtggcac ctgcgctcga gccgctacat
    10981 gaagagcacc acgggcaccc cccgggtgcc cgaggccctg ctgggcgggc cgctcggcat
    11041 cggcacctcg gcggccctgc tggtgccctc gatcctggcg gcgctgcccg cgcggctgcg
    11101 cgggttcacc cacgtcccgt tcgagaaggt gggcccgctg ccgcgccccg acttcgagat
    11161 gcccttccag acccggcaca acccccacct ggaggccacc cgccggcacg gcgtcgactg
    11221 ggcccgccgc acgggcatca ccgtccccag ccctaccgac cccctcgcgg gccactggga
    11281 cgaggagaac ctccacgact tcgacctggg gctgtgcgcc gccggcatca gcccggagtc
    11341 gagccccgac gaactggacc tcgccacgga ctggctcatc tggggcacct acgcggacga
    11401 cgtctacccc gcgcacttcg ggcggcgcgc cgacggcctg acggcggcga aggactgcac
    11461 cgaccggctc aagctgttca tgccgctgga cgccgtcgtc accgagacac cgctgaactg
    11521 cctggagcgg agcctggccg acatctgggt ccggacggtg acgcccatgc ccgccgccga
    11581 ccgcgcggtg ttccggcggg ccgtcgaggg gatgctggac agctggcagt gggagctgac
    11641 caaccagcgc atgaacaaga tccccgagcc ggtcgactac atcgagatgc gccgcgacac
    11701 cttcggctcc ccgctcacca tggcgctcgc ccggctccgc cacggcaagg cgctgccccc
    11761 ggaagtcctc gcctcccggc ccgtccaggc gctggagaac gccgcctcgg actacgccac
    11821 gctcatgaac gatgtcttct cctaccagaa ggagatcgag ttcgagggcg aggtccacaa
    11881 ctccgtcctg gtcgtccaga acttcttcga ctgcgggcgc gaggaggccc tgggcatcgt
    11941 cgccgacctg atgaggtccc ggatgcggga gttcctccac atcgtcgcca cgcaactgcc
    12001 cgccctgtgc gaggagttcg cgctcgacgt gaaggcccgc atcgccctgg acggctacgt
    12061 ccaggagctc aaggactggc tggcggccat cctcacctgg caccgggagt gccggcgcta
    12121 cggcgaggcc gacctggtcc gccgccgcgc cgcctctgcc gccgcgccgc ccctgcaggc
    12181 acccctgggc gcaccggccg gcctcggcac ctcggggacc cggctcacgt ccctcctgcg
    12241 gggctgacgc ctggggagta cggcgaaggc ccccaccgac cggtgggggc cttcgctgtc
    12301 gttcagtgcg ccaccaggga ctcgaacccc ggacctgctg attaagagtc agccgctctg
    12361 accaactgag ctagcggcgc gaaacgcata ctacccgatc ggctgacggg cttggtgcca
    12421 ttggcccatg gttgccctcc cctcctcagg ggcatgatcg cccggttggc tccacccctt
    12481 gcctacttca ggagatccca tgcagcggat cggtatcgcc gccaccgcgg cggccgccgc
    12541 cctcgcgctc gtccagatgc ccgcctccgc gcagccgccc accaccgcgg ccgacggacc
    12601 ggcgtcctgg acggcaccgt cctgcgcccg tgtcaccggt gacggctccg tcaccttcac
    12661 caccgacgac ggcaggaccc tcgcgcccac ctccggcacc ctcaaggcca ccggctacac
    12721 ccacggcctg gtcgcgctgg acaccccggg caccctgctc gccacccaca acgacgccct
    12781 gctgcgctcc accgacgccg gctgcgtctg gcagcgcgtc gccacgctcg gcggcgcttc
    12841 cacgcggctg gccgcggcac ccggcgggcg ggccttcgtc tggcagaaga acggccgcta
    12901 tctcgcccgc gtggacggca ccaccgtcac gcccctgaag gcgccgaccg cgcgcgtcag
    12961 cgggctgggg accgaccggg cgcggcccgg tcatgtgcgc ctggccgggg ccgacgggca
    13021 gttgtacgac tccgtggacg gcggggccac ctggcgccgc gccggcaccc cggcgttcgg
    13081 cggcacggcg agcgtctacg gcgtggcctt cgacccggcc gatccggatc acgccgtcgc
    13141 cggtggcatg gcgaccggtg gcgcggtgac caccgacggc ggcgtcacct ggcgggcggc
    13201 gcgcgggctt tcggccgacg gcgggcgggc gaacctcttc gacgccgccg tctcccccgc
    13261 cgaccctcac gtcgtctacg ccctgggcgt cgacctggtg gaggccgcgc cgggctcgtc
    13321 ctccgagggg cggcatctgt accggtcggc cgacggtggc ctgacgtacg ccaaggtcgt
    13381 cgacgactcc gccgccgtca agctcaccaa cggcacgctg ctggcaccca gtccggtcga
    13441 cccgaaggtc ctccacttca ccttcggcac atacttccag aactacggca ccgatctgtt
    13501 ccgctacgac gcctcgacgg gccgggtgac ggcgacgcac aacgcctacg acggcgtctc
    13561 cgcgatcgcc ttcaacccgg cccggccgga ggtgatgtac ctgggcgtgg aggaggtgcg
    13621 ggtcgactga cccgcaggac cccgcccgtc acgtcacgcg cgcccacctt tctcgcgcgg
    13681 ggtgcccttc accgtcacgg tgatgccgga ccgcgcgttg gcgacggtca ccgcgtacgg
    13741 cccgaacacc cgctcaggag gcgggagata gccgtcgggc accacggtct cgcgcaggta
    13801 gtacgcgccc ggcggcaggc cccggaaggc gcagcggccc gcgcggtcgg tggtgcagcc
    13861 ggggtcggcc cggcggtcgg gggcggcgcc cgcgatctgg agcccggggc ggcggttggt
    13921 ctcgcgccac agctcgaagc gggccccggg cagcggtcgg ccggtgcggg cgtccttggt
    13981 caccaggtgg atcgagccgt aggaggccgg gtcgggggtg ctgccgacgg tgagggagac
    14041 gccctcggcc gcgttgacgg cggtgagctc gagcggcccg aacaccgtgc ggtcgggcag
    14101 cttgtagccg ggcgggggct ggagctcctg ccagtagtag gtgccgggtt ccacggtggt
    14161 gcggcacacg ccgtgggtgt cggagacgca ctcgtcggcg gagcgggtgt cgggccggtc
    14221 gccggaggtc tggaggcccg ggacgccgtt ggtctcccgc cagagctgga aacgggcgcc
    14281 ctgcagcggc cggccgtcct gggcgtcccg gtccacgacc gtcacctctc cggtgggccg
    14341 gggcgggggc gcgcagtcgg ggaggtcgcc gttgaagggg taggcgtgga actcctggcc
    14401 gctgccgccg cccgtggcgg aggtgtgggt gagcgaaccg gcggtgagga agcggccgtt
    14461 catgcccggc agggtgaccg tggcctcgct ggtggggtcg cccaccagga cgctgccctg
    14521 gaactggccg gtgcccagga agtcgacgcg ccgggcgtcg gggacgttcc acaggaggcg
    14581 ctcgcgcagc cggttgaagg ggttgtcgtc ggtggcaccg ccactgaagg tgttgacgac
    14641 gcgggaggtg ccttcgaggt tgacgaggac ggtggcgccg gcggggatgc cggtgaagcg
    14701 aatggcctgc tggccgccgt cacggccgac gaggtcgaag ttgacgtgga acacctggag
    14761 ccgggaggtg ccgtcgccgg tgaacacggt ctccgtaccg gtgttgcggg cggtgccggt
    14821 ggcggggcgg ccgcgtccgt ccgcgccgcg ggcgtagcag cggccggcgg cgaggagccg
    14881 ctcgcgcagt ccggcgtagg gccgggcggc gcccgaggcc gcgacgtcgc cgccgatgac
    14941 caggccggag acgtcgcccg cgtgccggac gacgccgcgt tcggcgtcca gccgctggcc
    15001 gggggcgacg aggacgtccc cgtcggtggt caggaagtcg gcgccgtcgg acggggggac
    15061 gcgggagccg aagtggagga cgcccacggt gtagaggggg ccgccggagg tcttgttgac
    15121 gtcgaagtcg ccgagggtca ccacccggcc ctcggccccg gcggcgccgc cgcgtacgcg
    15181 gaagtcaccg ccggtgaaga ggttgatgtt gtcgtcgcgg cccgtgaacg gcctgtcgtt
    15241 gagggccggg taggtccggg ggcagctgcc cggcaggcag gggccgaggc cgccgggcag
    15301 cggggccgcc tgggcgggca gggccaggcc accgagggcg gcggccgcgg tggcggcgcc
    15361 ggccgccgtg cgccgcagcc atgtggtgca ccgggcgcgg aagcgggtcc ggggatcgtc
    15421 ggggggcctg gccgtgcctt cgttcacttt gtctccgcct ggtctaaccg atttgtcgac
    15481 gttttcgccg cacggtcccg actatggctt tgaccatctc ttcagatatt ccgacgcgcc
    15541 gggtcgtgac ccgaacagcc ccctccccgg cgcgcccggc cggacggcgt cacggacgcg
    15601 gcgtcacctc ggccatggcc gaccagccgg tgcccggcgt ctcgacgtgg atgatctccg
    15661 gcgtgctcgc gacgacgtcg ggcatccagg ccatggcggt cttgaagtgc tcggtgttga
    15721 cgtgcgtctc accggccgcg ctgtccttga acgcctccag caggacgaac tggtgggggt
    15781 tgtcgacgct cttggaccac tcgtagaaga cgttgccgtc ctccgcgcgg gtggcctcgg
    15841 tgaagtcctt gaccaggtcc agccactcgg cgctgcgctc ggggcggatg gtgaacttga
    15901 cggcgatgaa gatcatgcgt gctcctgggg ggtgcgaacg gctgatgcgg acggctgaat
    15961 cgccaccatc gtgccccggt ccctcgcggc ccgcgaacgc cggtgcgacc gattccggcc
    16021 ctgccggaaa accggccgcg gccgtcaccc gttcacccca ccagtgcggc cgcccggtct
    16081 cggagctccg ccagggccag ccgcagcagg gggtgcccct cgctgccccg gcggaccgcg
    16141 gtgaacaccc ggcgcgtggg gcccgggccg cgcagcggac ggacggcggg ggtgagcgcc
    16201 ggacggatgc cgtggagcgc cgagcgcggg acgagcgcga cgcccgcccc gacggccacc
    16261 agcgcgcaga ccgccgagaa gtcgtccgag aggcactcca cgcggggccg gaaccgggcc
    16321 tcctcgcagg cccgcaccac ggcctcgtgg acgggattgc ccggccaggg ggtgatccac
    16381 gggtcgtccc gcaggtccgt gaggtccacc tcgggcttgt cggcgaggcg gtggccgggc
    16441 ggcaggacgg cgtcgaaggg ctcctcgtag aggggggcgt gcagcagccg accggcgtcg
    16501 gaggccaggg cgtcgcggtg ctcgacggcc acggcgatgt cggcctcgcc gtccaggagc
    16561 agccgggcgc tggtgtgccc ctcggcgtcc ttgacccgca cccggacctg gggcgccctc
    16621 cggccgaggg cggccacggc gggggcgacg acctcggtga tggacgtggc gaaggccgcg
    16681 acggtcacct cgcccaccag accggtggag caccgggcca ggtcggcctc ggcccgctcc
    16741 agctgggcgg ctatctccac cgcgtgcccg gccaggacgc tgccggccgc cgtgagccgg
    16801 accgtgcggc cgcgccgctc cagcagggcg tgcccggtct ccgcctccag ggcggccagc
    16861 tgctgggaga ccgccgaggg cgagaggtac agggcgtggg cggccgcggt cacggtgccg
    16921 tggtcggcga gggcgctcag caccctgagc cggcgggggt cgatcatttg tccactatcg
    16981 cattcatgaa gcagagcttc acaggtgtca tcgcataacg ttgatggact tcacagtcct
    17041 cagccgccac agtgatcccc catgagggca ttggtgaaga ccgcggcggg gccgggtctc
    17101 gaactgaccg aggtaccgac ccccgaggcc ggtcccgggc aggtactgat caaggtgctg
    17161 cgcaccggca tctgcggcac ggacctgcac atcgacagct gggacgactg ggcggcccgg
    17221 gtggtccgcg cacccctcgt cgtcggtcac gagttcgcgg gcgaggtcgt ggagaccggc
    17281 gccggcgtga gcaccgtgag cgtcggcgac atcgtcagcg gcgagggcca cctcgtctgc
    17341 ggcacctgcc gcaactgcat ggccggccgc cgccacctgt gcatccgcac catcggcctg
    17401 ggcgtccaca ccgacggcgc gttcgccgag tacgtggtcc tgcccgagtc gaacgtctgg
    17461 gtccaccggc acgagatcga catcgacgtc gccgcgatct tcgacccgtt cggcaacgcc
    17521 gtgcacaccg cgctgtcctt cccggtgctc aacgaggacg tcctcatcac cggcgccggc
    17581 ccgatcggca tgatggccgc ggccgtcgcg aaccacgccg gggcgcgctc caccgtgatc
    17641 accgatgtga gcccctaccg gctcgccctg gcggagaaga tgggcgccac cgtcgccctc
    17701 gacgtcagcg accggcgcat cgccgacgtc atgccggagc tcggcatgac cgagggcttc
    17761 gacgtcggca tggagatgtc cggccgcgcc gacgccctcc aggacatgat cgcgaccatg
    17821 tcccccggcg gccggatcgc cgccctgggc ctgcccaccg gcgacgtgag catcgacatg
    17881 gccaccgtcg tcacccgcat gctgacgctg cgcggcatct acggccgcga gatgttcgag
    17941 acctggtacg cgatgtccgt gctgctgcgc agcggcctcg acatctcgcc ggtgataacg
    18001 caccgcttcg gtttcgagca gtacgccgag gccttcgcca cggcccgctc cggccagtgc
    18061 gggaagatcg tcctcgactg gacccgtccg gtcctcccct gacgccgtcc cgcccccacg
    18121 ccggtcatcc ccctggcgta cgaccacacc acgaggagtc ccccgtgttc gacagcatgc
    18181 gcgagcacct gcgcaaggag ctgcaggaca tccgtgacgc cgggctgtac aagtccgagc
    18241 gcgtgatcac cagcccgcag tccgcggcca tcagcgtggg tgacggcaag gtcctgaact
    18301 tctgcgccaa caactacctc gacctcgccg accaccccga ggtcatcgcc gccgccaaga
    18361 cggccctgga cgactggggc ttcggcatgg cctccgtccg gttcatctgc ggtacccagg
    18421 cgccgcacaa ggagctcgag gagaagatct cccggttcct cggcatggag gacacgatcc
    18481 tctacagctc ctgcttcgac gccaacggcg gtgtcttcga gacgctgctg acggccgagg
    18541 acgcggtgat ctccgacgag ctcaaccacg cgagcatcat cgacggcatc cgcctgtcga
    18601 aggcggcccg cttccgctac cgcaaccgtg acatggccga cctggagcgc tgcctcaagg
    18661 aggcctccgg cgcccggcac aagctgatcg tcaccgacgg cgtcttctcc atggacggct
    18721 acatcgcccc cctggacgag atctgcgacc tggccgagcg ctacggcgcc ctcgtcatgg
    18781 tcgacgactc ccacgccgtc ggcttcgtcg gcgaggaggg ccgcggcacg cccgagctgt
    18841 tcggggtgac cgagcgggtc gacatcatca ccggcaccct cggcaaggcc ctcggcgggg
    18901 ccagcggcgg ctacgtcgcc gcgcgcgccg agatcgtgga gctgctgcgc cagcgctcgc
    18961 gcccgtacct cttctcgaac tccctcgcgc cgtccatcgt cggcgcctcg ctgcgggtgc
    19021 tcgacctgct gaccgagtcc ggtgaccgcc gggcgcggct gcgggagaac accaagctct
    19081 tccgcgcgga gatgaccgcc gcgggcttcg acatcctgcc gggcgagcac ccgatcgccc
    19141 cggtgatggt cggtgacgcc gcgctggccg gccggatggc cgcggcgctg ctggagaagg
    19201 gcatctacgt gatcgccttc tcctaccccg tcgtgcccaa cggcaaggcg cgcatccgcg
    19261 tccagctgtc cgccgcgcac tcccgcgagg atgtgctgcg cacggtcgcc gcgttccgcg
    19321 aggtccgcga cgcgctggtc gcggcctgaa gctgaggttc atggggcccg tcccggtctt
    19381 ccggggcggg ccccacggcg tgcgccggac ctactccgcg aggccggcga cgcccgcctt
    19441 cgcgtacttc tcgtcgagat cgccgctggg cgcgcccgcc acgccgatgc ccgcgaccgg
    19501 ggcgcccttg tcctggacgg gggcgccgcc gggcaggaag agggtgcccg ggatgtcctt
    19561 gaggttcggg gtctgctgga gccgcttgac cagctccgag gtcggggcgt tccaggagac
    19621 ggccgtgaac gccttgcgct cggcggactc gtaggactgc gggcccgcgc cgtccccgcg
    19681 cagggtcacc acggtgttgc cgtcgcggtc gacgacggcg acggacacct tctgcccgtc
    19741 cttcttcgcg gcggcgagcg cggcctgcgc ggccttggtc gccgcgtcca ccgacagccg
    19801 gttcacctgg accaggccct tggcgaccgg ggccggggcg gcggcgggaa cgggggccgc
    19861 cgtggcagcg acggcgccga aggtgacggc accggcgacg gccacggcga cggagccggc
    19921 gatcacacgg gcgcggacgg agacgttctg gaggctcttc atggggaact cctgacggaa
    19981 ctgatcggag ccgatcggga cgtctccatc ctcgaagcga tcacgacccc ttccggtcgt
    20041 cggtccggag ggcatccgcg cgcggttcgg acgacccggg gtcgaccgat cggatgatgc
    20101 gagggcgatc accaggggtt aggacagaag acgtgaacac gtacgtgacc ggcaccgccc
    20161 caccgctccc ggaccgcgac cccgacgcgc ggtggttcgc cgtcgtccgg cacaccgcgt
    20221 tcttcctcct cctcggcgcg tccctcgtcc gcttcctgat ccgtcacgcg ggccacccgg
    20281 acaccccgtg gatcatcgcc ctgagcaccc tcctcggcat cctctacgtg ctcggcgcgg
    20341 gcctcgacga cgccgccccg gcgcaccggc ggctgtggct cggcgcggtc gtcggggtgt
    20401 gggtggtgct ggtggtcgcg gccccgagct tcgcctggtg cgccgtgccg ctcgtctaca
    20461 ccgccctgcg caccctgccc gtccggggct ccctcgtgct gatcgcgggg ctgacggtct
    20521 tcgtcgtggc cgcgcagatc agcctcttcg gcttcgaccc caacctcgtc gtcgcgccgc
    20581 ccaccgtcgc cgcgctggcc accgccgcct ttgtgcacat ggagcggcag cgggcccggc
    20641 aggacgccct gatcggcgat ctgctgcgca cgcgccggga gctggccgcg accgagcgcc
    20701 gcgagggcgc gctcgccgag cggcagcggc tgtcgatgga gatccacgac accctggccc
    20761 agggcctgtc cagccagcag atgctgctcc aggcggccga ccggatctgg acggccgacc
    20821 cgggcacggc ccgccaccac gtccgcgcgg cggcggacgt cgccgcccgg ggcctggccg
    20881 aggcccgccg cttcgtccag gacctggccc ccgccgatct ggcgggcggg gtacccctgg
    20941 cggaggcgct gcgcgccctg gccgagcggg agccggtgcc cggcctcgcg gtgcgcttcc
    21001 accaggaggg gacgcccgtg cccctgccgg agagcgcgga gtcggcgctg ctgcggatcg
    21061 cgcagggcgc gctcgccaac gtccgcgagc acgcgggggc gagcaccgcg gccctcaccc
    21121 tcacctggct cgacgaccag gtcgtcctcg acgtcgccga cgacgggcgg ggcttcgacg
    21181 cctccaccgc cccggcggcc ggcccggggc gcggccacgg cctgcccgcg atgcgggccc
    21241 gcgcgggcag gctgggcggc cggctgagcg tggagtccgt gcccggcgag ggcaccgtcg
    21301 tctccgccgc cctccccctc gtctcccccg actccccgga gctgccatga gcgccgccac
    21361 gcccgtccgt ctgctgctgt gcgacgacca cgccgtcgtc cgcgccgggc tgcgcgccct
    21421 gttcgccagc gagcccggca tcgaggtcgt cggcgaggcg ggtaccggcg aggaggccgt
    21481 cgccatggcg gcgaagctgc ggccggacgt ggtgctgatg gatctccagc tgggcccggg
    21541 catcggcggg gtggaggcca cgcgccgcat caccgccgcg ccggacgagg tgcgggtgct
    21601 ggtgctcacc acctacgaca cggacgccga cgtcacccgc gccctggagg ccggggccac
    21661 cggctatctg ctgaaggccg agcggcccga ggagctcttc gcggccgtcc gggccgccgc
    21721 ccagggccgt acggcgctct ccccgccggt ggccggccgg gtcatggccc ggctgcgcgg
    21781 cacccggccc gccaccggca cgctcaccga ccgcgagcgc gacatcctgg accagctcgc
    21841 gcgcggcctc ggcaaccggg acatcgcccg ggcgctgttc atcagcgagg ccacggtcaa
    21901 gacccacctg ggccgcatct acgccaagct gggcgtggac acgcgggcgg gggcggtggc
    21961 cgtggcgaag gagcagcggc tgctgggctg actttcagcc cgtccggcgt ttgaggaccg
    22021 gggtctgggg cggagcccca ggaaacggtg agagggcggg accggggcct catcccccac
    22081 acagctagta ggactccgtt aggtcttcct ggcgggtttg ttcggtggca tgttgggtgt
    22141 atggacgcgc ttgaagtggg ccgtgttcgg gtgaagttgg ggttgttcgt cgctgatgtg
    22201 ttcgcgtcgg tgccgcggaa ggaccagcgg gccaagagcg actgcta
//
