LOCUS       NZ_CP034587            21236 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 221440
            Orig. end                         :: 242676
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21236
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21236
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21236
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11236](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11236)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(188..199)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(549..563)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.34"
                     /tool="antismash"
     misc_feature    579..593
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.77"
                     /tool="antismash"
     misc_feature    580..592
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    complement(583..596)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    complement(583..597)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.48"
                     /tool="antismash"
     misc_feature    complement(584..597)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.08"
                     /tool="antismash"
     misc_feature    584..598
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.16"
                     /tool="antismash"
     misc_feature    complement(587..600)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.92"
                     /tool="antismash"
     misc_feature    complement(601..619)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    609..623
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.2"
                     /tool="antismash"
     gene            690..1592
                     /locus_tag="EKH77_RS01025"
                     /old_locus_tag="EKH77_01025"
     CDS             690..1592
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-273). E-value:
                     6.8e-23. Score: 73.5. Matches aSDomain:
                     nrpspksdomains_EKH77_RS01025_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268078.1"
                     /locus_tag="EKH77_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01025"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_126912552.1"
                     /sec_met_domain="PF00561 (E-value: 1.2e-19, bitscore: 69.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.1e-10, bitscore:
                     41.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEEKALNVGPSAIEVVYERFGDPKAPPVLLVMGGGAQMIHWPEG
                     FCTELVDRGVQVIRFDNRDSGRSSHFPHVPPPDLQAAMAGDFSSASYTLSDMAADAVGL
                     LDALGFDSAHVVGASLGGMIAQMIAIEHPTRIRSLTSMMSTTGDRAVGQPDFTVLAGLG
                     APPEDRQSFIGWQVRAMRAIGSPGFKPDDAGVAERAGRAYDRGHDRVGMLRQAIAVLAS
                     GDRTERLRTLSLPTLVIHGADDAMCDVSGGRATAAAVPGATLEIFDGLGHNFPRELWPG
                     IATLIADLVHRAEADPPGA"
     aSDomain        768..1508
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS01025_Abhydrolase_1.1"
                     /evalue="6.80E-23"
                     /label="EKH77_RS01025_Abhydrolase_1.1"
                     /locus_tag="EKH77_RS01025"
                     /protein_end="273"
                     /protein_start="26"
                     /score="73.5"
                     /tool="antismash"
                     /translation="PPVLLVMGGGAQMIHWPEGFCTELVDRGVQVIRFDNRDSGRSSHF
                     PHVPPPDLQAAMAGDFSSASYTLSDMAADAVGLLDALGFDSAHVVGASLGGMIAQMIAI
                     EHPTRIRSLTSMMSTTGDRAVGQPDFTVLAGLGAPPEDRQSFIGWQVRAMRAIGSPGFK
                     PDDAGVAERAGRAYDRGHDRVGMLRQAIAVLASGDRTERLRTLSLPTLVIHGADDAMCD
                     VSGGRATAAAVPGATLEIFDGLGHN"
     CDS_motif       1029..1076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EKH77_RS01025_0001"
                     /evalue="1.10E-03"
                     /label="NRPS-te1"
                     /locus_tag="EKH77_RS01025"
                     /protein_end="129"
                     /protein_start="113"
                     /score="11.5"
                     /tool="antismash"
                     /translation="HVVGASLGGMIAQMIA"
     gene            complement(1598..2830)
                     /locus_tag="EKH77_RS01030"
                     /old_locus_tag="EKH77_01030"
     CDS             complement(1598..2830)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548927.1"
                     /locus_tag="EKH77_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01030"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_126912553.1"
                     /transl_table=11
                     /translation="MRNTDILISGAGIGGTALAYWLRAAGFAVTVVERAPEPRPGGQTV
                     DLRGAGRTVVSRMGLMDRARALAVDQRGFAYVNGAGRITARMPADSFGGEGIISEIEIL
                     RGDLARLLYDATLPDTEYLFDDTVTRLDEDDDGVTVTFEKAAPRRFGLVFGADGLHSAV
                     RALAFGPEPDCVRPLNAYTAWFTAAEDLRLDGWMLMYNEPGGLVASARPGRLPGEIKAG
                     LGFRSAPLAYDRRDISAQQDLVARRFAGAGWEVPRLLRAMRAAPDFFLDSMAQVRLDSW
                     SRGRAALVGDAGYCATPLTGLGTSLALVGAYVLAGELASAGGDHRIAFRKYDEVMRPYV
                     DQAQQLPPGGASGYAPSSALAIGLRNLSMRAMNHWPMKNVLAAQFAKAGNIALPEYDRL
                     AAAGGGAGDRG"
     gene            2975..3922
                     /locus_tag="EKH77_RS01035"
                     /old_locus_tag="EKH77_01035"
     CDS             2975..3922
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548926.1"
                     /locus_tag="EKH77_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01035"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_126912554.1"
                     /transl_table=11
                     /translation="MNGQAAPRYTRIADELRQRIEAGELAPGDRVPSTREITRQWGVAM
                     ATATKVLTELRDQGLVRAVPGVGTVVEPAVRRPEQPAQPQPAPPRRKGTADQALTPARI
                     AEVAVAVADVEGLAAASMRRVAAELEVATMSLYRHVADKDALLLEMMDAVFRRWSLPEN
                     PSGGWRERLELVARTLWRMFRRHPWLAPALSVTRPQMVAGALPFSEWALAALEGRGLDP
                     STAFTAHLTLFTYVRGTAVNVEMEAEAEALSGLDSEEWMTSQEPALLAALTGDRFPRMR
                     HLATTGYDFDLDDLFEFGLQRLLDGLAVFLGEAP"
     gene            4030..4470
                     /locus_tag="EKH77_RS01040"
                     /old_locus_tag="EKH77_01040"
     CDS             4030..4470
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012859.4"
                     /locus_tag="EKH77_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01040"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_126912555.1"
                     /transl_table=11
                     /translation="MRTRAVVATMALALAGGGFLGTPASAIAASPAQEWVVNNPRAVIV
                     QRTSGLCLTATGGADSAVTTRGCRDAPGQRFMMEGGDIRNQAGGLCLTATGLDQPTVMR
                     PCNGSAGQRFFVQGPDIRSQASGRCLTATAPERPVLLTPCRA"
     gene            complement(4494..5219)
                     /gene="lepB"
                     /locus_tag="EKH77_RS01045"
                     /old_locus_tag="EKH77_01045"
     CDS             complement(4494..5219)
                     /EC_number="3.4.21.89"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138271.1"
                     /locus_tag="EKH77_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01045"
                     /product="signal peptidase I"
                     /protein_id="WP_126912556.1"
                     /transl_table=11
                     /translation="MTTGENEGNHEENNEENTARGTRRKRSGWREIPLLIGLALVLALA
                     IKTFLVQPFSIPSGSMENTLRTDDRVLVDKLTPWFGGTPHRGEVVVFKDPGGWLSDKLP
                     ERSNAFQRGVRKSLAFVGLMPSADEKDLIKRVIGVGGDTVECRRGEPVKVNGKPLDEPY
                     IHPGATPCDDMPVGTVKVPKDHLWVMGDHRDDSRDSRAHVHEPGGGFVPVDNVIGRAVV
                     VAWPVSRWATLPVPGTFDR"
     gene            complement(5274..6083)
                     /locus_tag="EKH77_RS01050"
                     /old_locus_tag="EKH77_01050"
     CDS             complement(5274..6083)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (25-128). E-value:
                     1.4e-22. Score: 72.5. Matches aSDomain:
                     nrpspksdomains_EKH77_RS01050_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986973.1"
                     /locus_tag="EKH77_RS01050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01050"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_126912557.1"
                     /sec_met_domain="PF00561 (E-value: 5.6e-17, bitscore: 60.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.5e-14, bitscore:
                     51.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDAVVTTEGDRIRWAELPGREPTRVYVHGLGATSPAYFAGVAAH
                     PLLAGHRSLLVDLLGHGISDRPVTFDYTLEGHADALAAALTAAGAAGAEVIAHSMGGSV
                     AVVLAARHPHLVSRLVLVDANLDPIPPTPGSGGSSGIAAHTEEEFLAGGWREVRDRAGA
                     HWWSTMRLAGLEALHRSAVHLTRGSVPIMREILMELTIPRTFLLPEDDGPLPGADALAE
                     AGVAVVPIPDCGHNIMLDNPEAFARATAHALAPTTTTTSHIVGTPVR"
     aSDomain        complement(5700..6008)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EKH77_RS01050_Abhydrolase_1.1"
                     /evalue="1.40E-22"
                     /label="EKH77_RS01050_Abhydrolase_1.1"
                     /locus_tag="EKH77_RS01050"
                     /protein_end="128"
                     /protein_start="25"
                     /score="72.5"
                     /tool="antismash"
                     /translation="VYVHGLGATSPAYFAGVAAHPLLAGHRSLLVDLLGHGISDRPVTF
                     DYTLEGHADALAAALTAAGAAGAEVIAHSMGGSVAVVLAARHPHLVSRLVLVDANLDP"
     misc_feature    6064..6079
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            complement(6164..7771)
                     /locus_tag="EKH77_RS01055"
                     /old_locus_tag="EKH77_01055"
     CDS             complement(6164..7771)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539468.1"
                     /locus_tag="EKH77_RS01055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01055"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_206279787.1"
                     /transl_table=11
                     /translation="MITVRDAELRAGARLLLSGISFTVSPGDRVGLVGRNGAGKTTLMT
                     ALAGLARPAAGTVTRTGPVGHLAQDSRAADPAVTVTDRILSARGLDRALRRLRAAEAAM
                     AEATGPGALDRAMNAYARAEAAFQAAGGYAAEAEAARVAAGLGLPDRVMGEPVGVLSGG
                     QRRRVELARILFAGHEDGTLLLDEPTNHLDADSVAWLRAFLQGHRGGLVVISHDTSLLT
                     DVVNRVFHLDPRRATIDIHNTGWTTYLTQRETDERRRARERANAERKAAALHAQADKMK
                     ARSATAVVARSMARRADRMLAGLEPARHAEKVARIRLPEPEPCGRTPLGAISLTKSYGD
                     HPVLTGVDLAVDRGSRLVVLGLNGAGKTTLLRVLAGTERPDSGRVTHGHGLRLGYFAQE
                     HDTLARERTVRENLADAAPHLTDGEIRRVLGAFLFSGDDADKPAGVLSGGEKTRLALAG
                     LVHSGANVLLLDEPTNNLDPASRDEVLAAVGSYPGAIVMVTHDEGAIDALRPDRVLLLP
                     DADEDLWSEDYRDLVSLA"
     misc_feature    7754..7768
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            complement(7898..8308)
                     /locus_tag="EKH77_RS01060"
                     /old_locus_tag="EKH77_01060"
     CDS             complement(7898..8308)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059343.1"
                     /locus_tag="EKH77_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01060"
                     /product="VOC family protein"
                     /protein_id="WP_126912558.1"
                     /transl_table=11
                     /translation="MTHLGLVTLVVRDYDEAIAFYRDAVGFDLLEDTRLDDGKRWVVVA
                     PPGAKETALLLAEAATGEQAARVGDQTGGRVGWFLNTEAFERDYERMRAAGVVFDEEPR
                     REPYGTVAVFRDLYGNRWDLIQHDRADGGATR"
     misc_feature    8414..8429
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.02"
                     /tool="antismash"
     gene            complement(8436..8669)
                     /locus_tag="EKH77_RS01065"
                     /old_locus_tag="EKH77_01065"
     CDS             complement(8436..8669)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130385.1"
                     /locus_tag="EKH77_RS01065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01065"
                     /product="chaplin"
                     /protein_id="WP_126912559.1"
                     /transl_table=11
                     /translation="MSIRNAAAVTVMAAAAIGAGATGATADQAHGSACKSPGVLAGNVA
                     QVAPRVSPNVGGNAISVVGVLNSSQGNALINK"
     gene            8929..9099
                     /locus_tag="EKH77_RS32830"
     CDS             8929..9099
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS32830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164737687.1"
                     /transl_table=11
                     /translation="MAKDKDMDDRRQQLSDDARFFLSGLPRADREKALRERTPKQLDEA
                     GKEVRSALTEE"
     gene            complement(9112..9975)
                     /locus_tag="EKH77_RS01070"
                     /old_locus_tag="EKH77_01070"
     CDS             complement(9112..9975)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640631.1"
                     /locus_tag="EKH77_RS01070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01070"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_126912560.1"
                     /transl_table=11
                     /translation="MTTTPSATAAVLRTEFQKAVAAYWNTNQQDPVNLRLGEVDDLYHH
                     HYGLGDYDPSVLEGPAATREQRIIEEMHRLETAQADVLLDHLGAITPQDRLLDGGSGRG
                     GTSVMAHQRFGCAVDGVSISEYQVGFANEQARKRGIDESVKFHFRNMLDTGFETASRRA
                     IWTNETTMYVDLFELFGEFSRLLEFGGRYVCITGCSNDVKGLRSKAVSRIDEHYTCNIH
                     PRSAYFKALAANNLTPISVVDLTPATIPYWELRAKSEVATGIEEAFLTAYKEGSFHYLL
                     IAADRV"
     misc_feature    complement(9984..10002)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    complement(9992..10007)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            complement(10001..11236)
                     /locus_tag="EKH77_RS01075"
                     /old_locus_tag="EKH77_01075"
     CDS             complement(10001..11236)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890277.1"
                     /locus_tag="EKH77_RS01075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01075"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_164737688.1"
                     /sec_met_domain="T1TS (E-value: 6.5e-61, bitscore: 205.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLSRMSAPSATHDVARLVATLLSHQSGAAPLVPGARAAHGDVH
                     RRAASAREPLRAVPTGPTGLGTSGLRIPAARPTPGTTGVSSSSGKSNSLVPELYCPPPL
                     RDDRALGEEVNDRLVDWAEEIGIYPERLDRVRGTDLGRMMMLVHPQTDDPDRLLAAARC
                     ALAEWATDDYYCDDETMGSSPAHLGAHLGTALAAVDPAHLPEPHASELDEALRADPVRA
                     ALRSGFEHLARYADPSQLARVRQEIGGLFVGYGQEGSWRSTGKMPAVWEYLTHRRFNSF
                     LPCIALVDVMDGHPLSAAEYAEPRVRRVVTMAGTASTLVNDLYSMAKEKDATGLNFNLP
                     AAIVAEEKCSLREAVERSAAIHDELVRSFEREAAALSLTGSPALRRFLAGVWAWLGGNK
                     AWHAGSARYGTS"
     gene            complement(11277..12695)
                     /locus_tag="EKH77_RS01080"
                     /old_locus_tag="EKH77_01080"
     CDS             complement(11277..12695)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538392.1"
                     /locus_tag="EKH77_RS01080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01080"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_126912561.1"
                     /transl_table=11
                     /translation="MSTSALPEQQEYTGAQAQLSLGIAAARNLATTTKSLPQMQGISSR
                     WLIRMLPWVQVSGGTYRVNRRLVYEVGDGRVTFVQEGASVRVVPAELGELPLLRGFADT
                     GVLRALADRFEQREYEPGQVITEAGRPTDHVYLIAHGKVEKLGTGHYGEDTRRGVLADG
                     GFFGGRTLAPEPGDWDFTARALTACTVLALPRHAYEEVAGRSESLRSHVQRRGDEGERP
                     RNKRGEADIALASGHTGEPVLPGTFVDYELEPREYELSVAQTVLRVHSRVADLYNDPMN
                     QVEQQLRLTVEALRERQEHELVNNREFGLLHNVDYSQRVQTHSGPPTPDDMDELLSMRR
                     STKFFLAHPKAIAALGRECNKRGLAFDTADVEGHGMPAWRGVPILPCGKIPVTDEGTSS
                     ILAMRTGESAGGVVGLWQTGIPDEYEPGLNVRFMGINDQAVISYLVSTYYSAAVLVPDA
                     LGVLENVQIAGAPS"
     gene            complement(13089..13502)
                     /locus_tag="EKH77_RS01085"
                     /old_locus_tag="EKH77_01085"
     CDS             complement(13089..13502)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019325722.1"
                     /locus_tag="EKH77_RS01085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01085"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_126912562.1"
                     /transl_table=11
                     /translation="MEALYTAVATATHGREGRAVSSDGLLDVQLALPAQLGGNGAGTNP
                     EQLFAAGYAACFASALGLVGRQAKVDLGDAAVTAEVGIGKEGEGFGLAVTLRVELPDAV
                     DTATGRKLVEQAHQVCPYSNATRGNIPVELVVE"
     gene            13620..14117
                     /locus_tag="EKH77_RS01090"
                     /old_locus_tag="EKH77_01090"
     CDS             13620..14117
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986495.1"
                     /locus_tag="EKH77_RS01090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01090"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_126912563.1"
                     /transl_table=11
                     /translation="MTKPPITPSEHAPREDLLRLDRQLCFSLNAASRAFGAVYRTLLKD
                     LGLTYPQYLVMMVLWEHTELPVKRLGELLRLDSGTLSPLLKRLEAAGLVHRERSAQDER
                     SVLVRLTPAGTALREEAALVPVRIATATGFTAQEAGELRALLEKLTLALDGAAFDDGSL
                     CD"
     gene            complement(14176..14835)
                     /locus_tag="EKH77_RS01095"
                     /old_locus_tag="EKH77_01095"
     CDS             complement(14176..14835)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010043972.1"
                     /locus_tag="EKH77_RS01095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01095"
                     /product="1,4-alpha-glucan branching protein"
                     /protein_id="WP_126912564.1"
                     /transl_table=11
                     /translation="MSVIHRTTLTPTKEELLASWLPSRPWYRPGAGAPQLTKAGGFRLD
                     DPAGEVGIEFMVTTDTAGPEPVSYLVPLTYRGAPLEGAEDALVGTLEHGVLGKRWVYDG
                     CHDPVFTTAILALIEGRVQAQAQSVSDTLDEGIARSFTGQGPVAAAFTSVTDDTESTEL
                     TGAPHGAALRLHRVLRPGPDTAPEGATGHVLGWWNLQDGTRVQGLFATLSTTTSRD"
     gene            complement(14888..15343)
                     /locus_tag="EKH77_RS01100"
                     /old_locus_tag="EKH77_01100"
     CDS             complement(14888..15343)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139228.1"
                     /locus_tag="EKH77_RS01100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01100"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_126912565.1"
                     /transl_table=11
                     /translation="MDQIDRNILRELQKDGRLTIQDLAQRVGLTSSPCMRRVRQLEQDG
                     VIQGYRAVINPEAVGRGFEVLVSIEVKRDREAVEAFEAALQGIPDVIEAYRLFGSPGCL
                     LRIAVADLTAYERLWIERLTTLSGITEVNSQIIMKRVKEPQGLPVDD"
     misc_feature    15333..15353
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.87"
                     /tool="antismash"
     gene            15493..16515
                     /locus_tag="EKH77_RS01105"
                     /old_locus_tag="EKH77_01105"
     CDS             15493..16515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535669.1"
                     /locus_tag="EKH77_RS01105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01105"
                     /product="asparaginase"
                     /protein_id="WP_126912566.1"
                     /transl_table=11
                     /translation="MGQVVVISTGGTIASRWQGSGFAADARGGDVLATAAVPDGVTVRV
                     VDLMSVNSARLTTADQLALLRTVHEVLADPDVAGIVVTHGTDTLEESAFFVDLHHGDPR
                     PVVFTGAQLPLEDPNGDGPRNLHDALLTAASVRDLGVLVVFDGQVHAARGTIKVQTLAA
                     DAFADPSGSRVADVGPSGVVIHRRPERPEPLPLPAADGPLPRVDVVMHHCDADTLLFDA
                     AVGAGAQGVVLVATGAGNATPEIAAAVAGAASRGVLVAVTTRVPSGSVAEIYTHGGAVD
                     LVAGGAVLTGTLRAGQARIAVLAATLAATDPAARAEALRRALGAPAPAADAHGASLANA
                     "
     gene            16559..18010
                     /gene="aspA"
                     /locus_tag="EKH77_RS01110"
                     /old_locus_tag="EKH77_01110"
     CDS             16559..18010
                     /EC_number="4.3.1.1"
                     /GO_function="GO:0008797 - aspartate ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aspA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988107.1"
                     /locus_tag="EKH77_RS01110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01110"
                     /product="aspartate ammonia-lyase"
                     /protein_id="WP_126912567.1"
                     /transl_table=11
                     /translation="MTATVPHPATAPDSTLFRSEHDLLGDRDVPAHAYYGVHTLRAVEN
                     FPITGTPIAAYPDLVTALAAVKQAAALANRDLGLLPGDKADAIVRACEEIRAGRLHDHF
                     VVDVIQGGAGTSTNMNANEVIANRALEHLGHAKGDYRRLHPLEDVNAGQSTNDVYPTAV
                     RLSLQLAADGLLEAMEVLRLAFAAKAEEFADVLKMGRTQLQDAVPMTLGQEFAAYAVML
                     AEDRARLEEARALLREINLGGTAIGTGLNAHPEYPELACRHLGAITGVPLSVAGDLVEA
                     TQDMGAFVQLSGVLKRIAVKLSKTCNDLRLLSCGPRAGLAEINLPAVQAGSSIMPGKVN
                     PVIPEVVNQVAFEVIGNDVTVTMAAESGQLQLNAFEPVIAHSLLKSIAHLRSGCLTLAE
                     RCVTGITANREHLAQLVGQSIGLATALNPHIGYEKATAVAQEALTTGASVRDLVLAKGL
                     LTPERLEEILHPDNLARPHSAAVHG"
     gene            18068..19477
                     /locus_tag="EKH77_RS01115"
                     /old_locus_tag="EKH77_01115"
     CDS             18068..19477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100786.1"
                     /locus_tag="EKH77_RS01115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_01115"
                     /product="NAD-dependent malic enzyme"
                     /protein_id="WP_126912568.1"
                     /transl_table=11
                     /translation="MATAPSVSYSMTVRLEVPASGTAVSELTTAVESSGGSVTGLDVTA
                     SGHEKLRIDVTMATTSTEHADEIVEKLRGIEGVTLGKVSDRTFLMHLGGKIEMASKHPI
                     RNRDDLSMVYTPGVARVCMAIAENPEDARRLTIKRNSVAVVTDGSAVLGLGNIGPKAAL
                     PVMEGKAALFKRFAGIDAWPICLDTQDSDAIVEIVKAIAPGFAGINLEDISAPRCFEIE
                     ARLREALDIPVFHDDQHGTAIVVLAALTNALRVVGKNVGDVRVVMSGAGAAGTAILKLL
                     IAAGVRHAVVADIHGVVHTGRPDLVSASPDSALRWIADNTNPEGVTGTLKEAVRGADVF
                     IGVSAPNVLDGEDVAAMAPDSIVFALANPDPEVDPGIARKTAAVVATGRSDFPNQINNV
                     LVFPGVFRGLLDAQSRTVNTDMMLAAARALADVVAEDELNANYIIPSVFNAKATEAVAS
                     AVKQAALAARQ"
     misc_feature    complement(21009..21025)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.98"
                     /tool="antismash"
ORIGIN
        1 gcgccgcctc gaacgcgtcc cgggtgcgca gctccaccca tacggcgttt cctcccacac
       61 cgggcggccg gggccacccg ggctcggtcc ggcactccca caggccgaag gaggctccgg
      121 ccggatcggc cgcgagcgcg aggcgcccct cgtcggacga cagcggcccg acggcgacgg
      181 tgccgccgcg ttcctgtacg cggccgacgg cggtgtcggc gctctccgtg ccgaagtagg
      241 tggtccaggt gacggggagc tcccactcgt gggccgtcgc gttgataccg gcgaccgccg
      301 tcttgcccgc catcgcgtgg acgtaggagc cccgccggcc ggccacggtc tcgaaccgcc
      361 agcccagcag tggcccgtag aagtccttgg ccccgtccag gtcccgcgtg gccaggctca
      421 cccagcaggg aacacccggc agacacgcgc atctcgtgcc ggtcatgtcc ccagctcact
      481 ccccgttccc ggcatctgca accggggccg ggatccggga agaccgccta cggaattccc
      541 ccactccgca ttttcagcct atagctttcc ttcactattg tccattttgc aaaaattcca
      601 cctgttcgta ttttcagtcg ctttaaatgc aggtatgttc atgtctccac tcgactgatc
      661 tccactcgaa ccgaggagac gttgcggctg tgagcgaaga gaaagctctg aatgtcggcc
      721 cgtcggccat cgaagtggtc tacgagcgct tcggcgaccc caaggcaccg cccgtgctgc
      781 tggtgatggg cggcggcgcg caaatgatcc actggccgga gggattctgt accgaactcg
      841 tcgaccgcgg tgtgcaagtg atccggttcg acaatcggga ttccggccgg tcgtcgcatt
      901 tccctcacgt gccaccgccg gatctccagg ccgcgatggc cggtgatttc tcatcggcct
      961 cctacacgct gtcggacatg gcggccgacg ccgtcgggct gctcgacgcc ctcggattcg
     1021 acagcgccca tgtcgtcggc gcgtccctgg gcggcatgat cgcccagatg atcgccatcg
     1081 agcacccgac ccggatccgg tcgctgacgt cgatgatgtc caccaccggc gaccgggccg
     1141 tgggccagcc cgacttcacc gtcctggccg gactcggggc gccgccggag gaccggcagt
     1201 ccttcatcgg ctggcaggtg cgggccatga gggcgatcgg gtcccccggg ttcaagcccg
     1261 acgacgccgg agtggccgag cgggccggcc gcgcctacga ccggggccac gaccgcgtgg
     1321 gcatgctgcg ccaggccatc gccgtcctgg cctccggaga ccgcaccgag cggctgcgga
     1381 cgctctcgct cccgactctg gtgatccacg gcgcggacga cgccatgtgc gacgtcagcg
     1441 gcgggcgggc caccgcggcg gccgtccccg gcgccacgct cgagatcttc gacggcctgg
     1501 gccacaactt cccccgcgag ctgtggccgg gcatcgcgac gctgatcgcc gatctcgtcc
     1561 accgcgccga ggcggacccg cccggcgcct gacccggcta ccccctgtcg ccggcaccgc
     1621 cgcccgcggc ggcgaggcgg tcgtactcgg gcagggcgat gttcccggcc ttggcgaact
     1681 gtgcggcgag cacgttcttc atgggccagt ggttcatcgc ccgcatcgac agattccgca
     1741 agccgatggc cagcgcactg gagggcgcgt acccggaggc tccgccgggt ggcagttgct
     1801 gggcctggtc gacgtagggg cgcatgacct cgtcgtactt ccggaaggcg atccggtggt
     1861 cgccgccggc ggaggcgagt tcacccgcca ggacataggc gccgaccagg gccaggctgg
     1921 tgcccaggcc cgtgagcggc gtcgcgcagt agccggcatc cccgacgagc gcggcccggc
     1981 cgcgggacca gctgtcgagc cggacctgtg ccatggagtc gaggaagaag tcgggcgcgg
     2041 cgcgcatcgc ccgcagcagg cgcggcactt cccatcccgc gccggcgaag cgccgggcca
     2101 ccaggtcctg ttgcgcggag atgtcgcgcc ggtcgtaggc gaggggtgcc gagcggaaac
     2161 cgaggcccgc cttgatctcg ccggggagcc ggcccgggcg ggccgaggcg acgagtccgc
     2221 cgggctcgtt gtacatcagc atccagccgt cgagcctcag gtcctcggcg gccgtgaacc
     2281 aggcggtgta ggcgttcagc ggacgcacgc agtccggctc cggcccgaag gccagcgcgc
     2341 ggacggcgga gtggagtccg tccgcgccga agaccagccc gaaccggcgg ggggcggcct
     2401 tctcgaaggt gacggtgacc ccgtcgtcgt cctcgtcgag acgggtgacg gtgtcgtcga
     2461 agaggtactc ggtgtccggc agggtggcgt cgtacagcag acgggcgagg tcgccgcgga
     2521 ggatctcgat ctccgagatg atcccctcgc cgccgaagct gtccgccggc atccgggcgg
     2581 tgatacggcc ggccccgttg acgtacgcga agccgcgctg gtcgacggcg agcgctcgcg
     2641 cccggtccat caggcccatc cgcgagacca cggtacggcc cgcgccccgc aggtccacgg
     2701 tctggccgcc cggccggggt tccggcgccc gctcgacgac ggtgacggcg aagcccgccg
     2761 cgcgcagcca gtacgccagg gcggtgccgc cgataccggc accggagatg agtatgtcgg
     2821 tgttccgcat ggcactgaat gtacgccgta cacagcgcac tacgcaaggc caatcaccct
     2881 cccgagcagg tcatttggcc tggcaagtgc actagtacgc gggcgcggcg gctaggatgg
     2941 cggggattag gtgcactagt gcggagggaa aacggtgaac gggcaggcag caccccgcta
     3001 tacgcggatc gccgacgaac tgcggcagcg gatcgaggcg ggcgagctgg cgccgggcga
     3061 ccgggtgccc tcgacccggg agatcacccg gcagtggggc gtcgcaatgg cgaccgcgac
     3121 caaggtgctc accgagctcc gcgaccaggg cctggtccgc gccgtcccgg gcgtcgggac
     3181 ggtcgtcgaa cccgccgtgc gacgaccgga acagccggca cagcctcagc cggcgccccc
     3241 gcgccgcaag ggcaccgcgg accaggcact cacgccggcg cggatcgccg aggtggccgt
     3301 cgcggtggcc gatgtggagg ggctggcggc cgcctcgatg cgccgggtcg cggccgagct
     3361 ggaggtggcg accatgtcgc tgtaccggca cgtggccgac aaggacgcct tgttgctgga
     3421 gatgatggac gcggtgttcc gccggtggtc gttgcccgag aacccctccg ggggctggcg
     3481 ggagcggctg gagctcgtcg cccggacgct gtggcggatg ttccgccgcc acccctggct
     3541 cgcaccggcc ctctcggtca cccggccgca gatggtcgcc ggcgcgctgc cgttcagcga
     3601 gtgggcgctc gcggctctgg aggggcgcgg tctcgatccc tcgaccgcgt tcaccgccca
     3661 cctcacgctg ttcacctatg tgcgcggcac cgccgtcaac gtcgagatgg aagcggaagc
     3721 ggaggcgctc agcggcctgg acagcgagga gtggatgacc agtcaggagc ccgcgctcct
     3781 cgccgcgctg accggcgacc ggttcccgag gatgcggcac ctcgccacga ccgggtacga
     3841 cttcgacctc gacgacctgt tcgagttcgg tctgcagcgc ctcctcgacg gcctggccgt
     3901 gttcttgggc gaggcgccct gacccgccgt ctccctcgga cccgtacggg tgaggtgggg
     3961 tgtgcccggg ccggttcccg gaaacggtgc cagtgtccgt gcccgcgccc gtttccgaga
     4021 ggtcgcttca tgcgtacgcg cgctgtcgtc gccaccatgg cactcgccct cgccggtggt
     4081 gggttcctcg gaacccccgc ctccgccatc gccgcgtccc cggcccagga gtgggtggtg
     4141 aacaatccgc gcgccgtcat cgtgcaacgg accagcgggc tctgcctgac ggccacgggt
     4201 ggcgccgaca gtgccgtgac cacccggggg tgcagggacg caccggggca gcggttcatg
     4261 atggagggag gggacatccg caaccaggcc ggcggcctgt gcctcacggc caccggcctg
     4321 gaccagccca cggtgatgcg gccctgcaac ggatccgccg gccagcggtt cttcgttcag
     4381 ggcccggaca tccgcagcca ggccagcggt cggtgcctga cggccaccgc ccccgagagg
     4441 cccgtgctgc tgaccccgtg ccgggcctga cgcccgggtc gtacgccgcc gtgctatcgg
     4501 tcgaacgtgc cgggcacggg cagggtggcc caccgggaga cgggccaggc gacgacgacg
     4561 gcccggccga tcacgttgtc cacgggcacg aacccgccgc ccggctcgtg gacatgggcg
     4621 cgggagtcgc gtgagtcgtc gcggtggtcg cccatgaccc acaggtggtc cttgggcacc
     4681 ttcaccgtgc cgaccggcat gtcgtcgcac ggggtggcgc ccgggtggat gtacggctcg
     4741 tccaggggct tgccgttgac cttcacgggc tcgccgcgcc tgcactccac ggtgtcaccg
     4801 ccgaccccga tcacccgctt gatcaggtcc ttctcgtccg ccgagggcat caggccgacg
     4861 aaggcgaggg actttcgcac cccgcgctgg aaggcgttgc tccgctccgg gagcttgtcg
     4921 gacagccagc cgcccgggtc cttgaagacc acgacctcgc cccggtgcgg cgttcccccg
     4981 aaccagggcg tgagcttgtc gaccagcacc cggtcgtccg tccggagggt gttctccatc
     5041 gagccggagg gaatggagaa cggctgcacg aggaaggttt tgatcgccag cgcgagcacg
     5101 agggccaggc cgatcaggag gggtatctcc cgccatcccg agcgcttcct ccgcgtgccg
     5161 cgcgcggtgt tctcctcgtt gttctcctcg tggttcccct cgttctcccc ggtggtcatc
     5221 gctcgcctct ccccttggtc gtaccggggc tgtgatcggc acccggcagt gactcaacga
     5281 acaggggttc ccacgatgtg gctggtcgtc gtggtggtcg gcgcgagcgc gtgcgcggtg
     5341 gcgcgggcga aggcctcggg gttgtcgagc atgatgttgt gcccgcagtc gggaatcggg
     5401 accacggcca ccccggcctc ggcgagcgcg tcggcgccgg gcagcggacc gtcgtcctcc
     5461 ggcagcagaa acgtgcgcgg aatggtgagc tccatgagga tttcgcgcat gatgggcacg
     5521 ctcccccggg tgaggtggac cgcgctgcgg tgcagcgctt cgaggccggc cagccgcatg
     5581 gtggaccacc agtgcgcacc ggcccggtcg cggacctccc gccagccgcc ggcgaggaac
     5641 tcctcctccg tgtgggcggc gatgccgctg ctgcccccgg agccgggcgt gggcgggatc
     5701 gggtcgaggt tcgcgtcgac gaggaccagc cgggagacca ggtgcgggtg gcgggcggcc
     5761 aggacgacgg cgaccgagcc gcccatgctg tgcgcgatca cctccgcgcc ggcggcgccg
     5821 gctgcggtca gcgcggcggc gagcgcgtcg gcgtgcccct ccagggtgta gtcgaaggtg
     5881 acgggccggt cgctgatgcc gtgcccgagc aggtcgacga gcagggaccg gtgaccggcc
     5941 agcagcgggt gggccgcgac gcccgcgaag taggcgggcg acgtggcccc cagaccgtgc
     6001 acgtagacgc gcgtgggttc ccggcccggc agttcggccc agcggatccg gtcgccttcg
     6061 gtcgtcacga cggcgtctcg cacagctctt cccccatagc ccgagttcgg tgatcgtcag
     6121 ggggaagagc gtaaccgccc gcgccgttcg ggctcgggcc gcgtcaggcg agggagacca
     6181 ggtcccggta gtcctcgctc cacaggtcct cgtcggcgtc cggcagcagc aggacgcggt
     6241 cggggcgcag ggcgtcgatg gcgccctcgt cgtgcgtgac catcacgatc gcgccggggt
     6301 acgagccgac ggcggccagg acctcgtcgc gggaggcggg gtcgaggttg ttggtgggtt
     6361 cgtccagcag caggacgttc gcgccggagt ggacgagccc ggccagggcc aggcgggtct
     6421 tctccccgcc cgagaggacc ccggcgggtt tgtcggcgtc gtccccggag aagaggaacg
     6481 cgccgaggac gcgccgtatc tcaccgtccg tcaggtgggg ggctgcgtcg gcgaggttct
     6541 cgcggacggt gcgttcccgg gcgagggtgt cgtgctcctg ggcgaagtag cccagccgca
     6601 gcccgtgtcc gtgcgtcacc cgtccgctgt ccgggcgttc cgttccggcg aggacgcgca
     6661 gcagggtggt cttgcccgcg ccgttgaggc cgaggacgac gaggcggctg ccgcggtcga
     6721 cggcgaggtc gacgccggtg agcacggggt ggtcgccgta ggacttggtg aggctgatcg
     6781 cgccgagggg cgtgcgtccg cagggttccg gttcgggcag gcggatcctg gcgaccttct
     6841 cggcgtgccg ggccggttcg aggccggcga gcatgcggtc ggcccggcgc gccatgctcc
     6901 tggccacgac ggcggtggcg gagcgcgcct tcatcttgtc ggcctgggcg tggagggcgg
     6961 cggccttgcg ttcggcgttg gcgcgctcgc gtgcccggcg gcgttcgtcg gtctcccgct
     7021 gggtcaggta ggtggtccag ccggtgttgt ggatgtcgat ggtggcgcgt cgggggtcga
     7081 ggtggaagac gcggttgacg acgtcggtga gcagggaggt gtcgtggctg atcaccacca
     7141 ggccaccgcg gtgcccttgg aggaaggcgc gcagccaggc gacggagtcg gcgtcgagat
     7201 ggttggtggg ctcgtccagc aggagggtgc cgtcttcgtg tccggcgaag aggatgcggg
     7261 cgagttccac cctgcgtcgt tgcccgccgg agaggacgcc cacgggttcg cccatgacgc
     7321 ggtcgggcag tccgagcccg gcggcgacgc gggcggcctc ggcttcggcc gcgtagccgc
     7381 ccgccgcctg gaaggcggct tcggcgcggg cgtaggcgtt catcgcccgg tccagcgcgc
     7441 cggggccggt ggcctcggcc atggcggcct cggccgcgcg cagccggcgc agggcccggt
     7501 cgaggccgcg cgcggagagg atgcggtcag tgacggtgac ggcggggtcg gcggcacggg
     7561 agtcctgggc cagatggccg acggggccgg tgcgggtgac ggtgccggcg gcggggcggg
     7621 ccagtccggc gagggcggtc atgagggtgg tcttgcccgc gccgttgcgg ccgacgaggc
     7681 cgacgcggtc gccgggcgag acggtgaagg aaatgccgga cagcaggagg cgcgcgcccg
     7741 cgcgcagctc ggcatcacga acggtgatca tgggatgacg ctccgagaaa gcaaaaggac
     7801 acacttctgg cgtggaagcg ggtccttcgc taggaaactc ggggcataga catgggctca
     7861 ccgtaaccgg ccgcgcgcga gcggcgcacc cggtttttca gcgggtagcg ccgccgtcgg
     7921 cccggtcgtg ctggatcagg tcccagcggt tcccgtacag atcccggaag acggcgacgg
     7981 tgccgtacgg ctcgcgcctg ggctcctcgt cgaacacgac cccggccgcg cgcatccgct
     8041 cgtagtcgcg ctcgaacgcc tcggtgttca ggaaccagcc gacccggccg cccgtctggt
     8101 ccccgacgcg agccgcctgc tcgccggtcg cggcttcggc gaggagcagc gcggtctcct
     8161 tcgcgcccgg cggggcgacg accacccacc gtttgccgtc gtcgaggcgg gtgtcctcca
     8221 ggaggtcgaa gccgacggcg tcgcgataga aggcgatggc ttcgtcgtag tcgcgtacga
     8281 cgagggtcac gagtccgaga tgtgtcatgt ggcgatcttc cccgactgcc cacacatgcc
     8341 acagaggtgg ccggttccgt ccgggtggga cggtgccggc cacctctgct cgggtggggg
     8401 gaggtgctgg gccgtgaccg agaggtcagg accgcttact tgttgatgag cgcgttgccc
     8461 tgggagctgt tgaggacgcc gacgaccgag atggcgttgc cgccgacgtt cggggagacg
     8521 cggggcgcga cctgggcgac gttcccggcg aggacgcccg gggacttgca ggccgagccg
     8581 tgcgcctggt cggcggtggc gccggtggcg ccggcgccga tggcggcggc ggccatcacc
     8641 gtgacggcgg cggcgttgcg gatgctcatg tgctctctcc ttgattggtg gggggaggca
     8701 gtgcaaaagc tctggcaaga gagagtcttg cgtatgaaaa accgctgacg tgaccgatgg
     8761 cgatatgttc atccgctctg atgatcacgt gctcgccctt gaccccttgt gggtgtcgcc
     8821 ccctcgtccg cccggcgttc atccgcttgg aacgcctccg ggagccgatc cggtgcggag
     8881 gctgtccact gtgagggaga acgttccggc cggatcgagg gaggtcccgt ggccaaggac
     8941 aaggacatgg acgacaggcg tcagcagctc tccgacgacg ccaggttctt cctgagcgga
     9001 ctgccgagag cggaccgtga gaaggcgctg cgcgagagga cccccaagca gctcgacgag
     9061 gccggcaagg aggtgcggag cgccctcacg gaggagtagc cccggcacgg gtcagacgcg
     9121 gtcggcggcg atgagcaggt agtggaagct gccttccttg tacgcggtga ggaacgcctc
     9181 ctcgatgccc gtggccacct cggacttcgc gcgcagctcc cagtagggga tggtggcggg
     9241 ggtgaggtcc acgacgctga tcggcgtcag gttgttggcg gccagggcct tgaagtaggc
     9301 gctgcgcggg tggatgttgc aggtgtagtg ctcgtcgatg cggctgaccg ccttggagcg
     9361 caggcccttg acgtcgttgg agcagccggt gatgcacacg taccggccgc cgaactccag
     9421 gagccgggag aactcgccga acagctcgaa gaggtccacg tacatggtgg tctcgttggt
     9481 ccagatcgcc cggcgggagg cggtctcgaa gccggtgtcg agcatgttgc ggaagtggaa
     9541 cttcacgctc tcgtcgatac cgcgcttgcg cgcctgctcg ttggcgaagc cgacctggta
     9601 ctccgagatc gacacgccgt ccaccgcgca gccgaagcgc tggtgggcca tgacgctggt
     9661 gccgccgcgg ccggaaccgc cgtccaggag gcggtcctgg ggggtgatgg cgcccaggtg
     9721 gtcgaggagg acgtcggcct gggcggtctc caggcggtgc atctcctcga tgatgcgctg
     9781 ctcccgggtc gccgcgggcc cctccaggac cgaggggtcg tagtcgccga gcccgtagtg
     9841 gtggtggtag aggtcgtcga cctcgcccag gcgcaggttg accgggtcct gctggttggt
     9901 gttccagtac gcggccaccg ccttctggaa ctcggtgcgc aggactgccg cggtggcgga
     9961 gggcgtggtg gtcaactcgt tctccttaac ggtttacaac ttacgacgtg ccgtagcggg
    10021 cgctgcccgc gtgccaggcc ttgttgccgc cgagccaggc ccacactccg gcgaggaagc
    10081 ggcgcagggc cggggagccg gtgaggctga gggcggccgc ctccctctcg aaggagcgca
    10141 cgagctcgtc gtggatcgcg gcgctccgct cgacggcctc ccggagcgag cacttctcct
    10201 ccgcgacgat cgccgcgggc aggttgaagt tcaggccggt ggcgtccttc tccttggcca
    10261 tcgaatagag gtcgttcacg agcgtgctcg cggtgcccgc catggtgacg acgcggcgca
    10321 cgcgcggttc ggcgtactcg gcggcggaca gcgggtgtcc gtccatcacg tcgacgaggg
    10381 cgatgcaggg caggaagctg ttgaagcgcc ggtgggtgag gtactcccac acggcgggca
    10441 tcttccccgt gctccgccag gagccctcct gcccgtatcc gacgaacagt ccgccgatct
    10501 cctggcgcac ccgggccagc tggctcgggt ccgcgtagcg ggcgaggtgc tcgaaaccgg
    10561 accggagggc ggcgcggacg gggtccgcgc gcagggcctc gtcgagttcc gaggcatggg
    10621 gctcggggag gtgggcgggg tcgacggccg cgagggcggt cccgaggtgg gcgccgaggt
    10681 gggccgggga ggagcccatg gtctcgtcgt cgcagtagta gtcgtccgtg gcccactcgg
    10741 cgagcgcgca gcgggcggcc gccagcagcc ggtccgggtc gtcggtctgg gggtggacga
    10801 gcatcatcat gcgcccgagg tcggtgccgc ggactcggtc gagccgctcc gggtagatgc
    10861 cgatctcctc ggcccagtca accagccggt cgttgacctc ttcgccgagg gcccggtcgt
    10921 cgcggagcgg cggcgggcag tacagctcgg ggacgaggga gttcgactta ccggacgagc
    10981 tggatacgcc cgtcgtcccg ggcgtgggcc gggcggccgg gatgcggagg ccggaggtgc
    11041 cgaggccggt cggaccggtg ggcacggccc ggagcggctc ccgcgcggac gccgcgcgcc
    11101 ggtggacgtc gccgtgcgcg gcgcgggcgc cgggcacgag gggggccgcc ccgctctggt
    11161 gggacagcag tgtggccacc agcctcgcca cgtcgtgggt ggccgagggt gcggacatgc
    11221 gggacagcag cgacaccggt tctctccgtt cctctccgtt ctcgggtgcg gcggtgtcag
    11281 gaaggcgcgc cggcgatctg gacgttctcc agcaccccga gggcgtcggg cacgagcacg
    11341 gcggcggagt agtaggtgct gaccaggtag gagatgacgg cctggtcgtt gatgcccatg
    11401 aagcggacgt tcaggccggg ctcgtactcg tcggggatgc cggtctgcca caggccgacc
    11461 acgccgccgg cggactcgcc ggtgcgcatg gcgaggatcg aggaggtgcc ctcgtccgtg
    11521 accgggatct tgccgcaggg caggatcggg acgccgcgcc aggcgggcat gccgtggccc
    11581 tcgacgtcgg cggtgtcgaa ggcgagcccg cgcttgttgc actcgcggcc gagggcggcg
    11641 atggccttcg ggtgcgcgag gaagaacttg gtgctgcggc gcatgctcag cagctcgtcc
    11701 atgtcgtccg gggtgggcgg gccggagtgg gtctggacgc gctggctgta gtcgacgttg
    11761 tgcagcaggc cgaactcgcg gttgttgacg agctcgtgct cctggcgttc gcgcagtgcc
    11821 tcgacggtca ggcgcagttg ctgctcgacc tggttcatgg ggtcgttgta gaggtcggcg
    11881 acccggctgt ggacccgcag gacggtctgg gcgacgctca gctcgtactc gcgcggttcg
    11941 agctcgtagt cgacgaaggt gcccgggagg accggctcgc cggtgtgccc ggaggcgagg
    12001 gcgatgtcgg cctcgccgcg cttgttccgg gggcgctcgc cctcgtcgcc gcgccgctgg
    12061 acgtgggagc gcagcgactc gctgcggccg gccacctcct cgtacgcgtg gcgcggcagg
    12121 gccagtacgg tgcaggcggt cagggcgcgg gccgtgaagt cccagtcgcc gggctcgggg
    12181 gccagggtcc gcccgccgaa gaagccgccg tcggccagca cgccccggcg ggtgtcctcg
    12241 ccgtagtggc cggtgccgag cttctccacc ttgccgtggg cgatcaggta cacgtggtcg
    12301 gtgggccggc cggcctcggt gatgacctgg ccgggctcgt actcccgctg ctcgaagcgg
    12361 tcggcgaggg cgcgcaggac gcccgtgtcg gcgaagccgc gcagcagggg cagctcgccg
    12421 agctcggcgg ggacgactct gacgctcgcg ccctcctgga cgaaggtgac gcggccgtcc
    12481 ccgacctcgt agacgagccg ccggttgacc cggtaggtgc cgccgctgac ctggacccag
    12541 ggcagcatgc ggatcagcca gcgcgagctg atgccttgca tctgcggcag ggacttggtg
    12601 gtggtcgcga ggttccgcgc cgccgctatg cccaggctga gctgtgcctg ggcaccggtg
    12661 tactcctgct gctccggcag cgctgaggtc gacatcccag gtccttccgt ctcggggccc
    12721 gtaacggcct gcggagcgct ggtgcccacg gcggtgacct gcggtgacgg cgctccggcg
    12781 ggagtgaatc aggccggggc ggcaccggtc gaaagcgggc ggccgggtgg gtcggattca
    12841 cgccacatac ggatcggagg accctctggc cacttgagtc actccggtcg gtgtgtcaag
    12901 ggccttttgg ggaagatcga ttgggccgtt cgggcccggt ggttcaccgc cgacatccgg
    12961 gtcgacatgt ccgggtcaat gacggggagg tcatggggga accggggtgt gcggtgttcg
    13021 aggatgacga aaactcttcg ttcggcggcc ggcaggcccc ggtcggggcc cgcttcagcc
    13081 gcgggtcgtc actcgacgac gagctcgacc gggatgttgc cgcgggtcgc gttggagtag
    13141 gggcagacct ggtgggcctg ctcgaccagc ttgcggcccg tcgcggtgtc gaccgcgtcg
    13201 gggagctcca cgcgcagcgt gaccgccagc ccgaagccct cgccctcctt gccgatgccg
    13261 acctcggcgg tcaccgcggc gtcaccgagg tcgaccttcg cctgccggcc gaccagaccg
    13321 agggcgctgg cgaagcacgc cgcgtacccg gcggcgaaca gctgctccgg gttggtgccg
    13381 gcgccgttgc cgccgagctg cgccgggagg gccagctgga cgtcgaggag gccgtcggag
    13441 ctgacggcgc ggccctcacg gccgtgggtg gcggtggcga cggcggtgta cagggcttcc
    13501 atgggaacca tccctctcgg agatcgcggc gagggcctgt ccggcccgcc tgacacccat
    13561 caaggtagtg cacgattcag ttgtgcgcaa ttaaatgccc ggcgagatac cctgggcgca
    13621 tgacgaagcc gccgatcacc ccctccgagc acgcgccccg cgaggacctc ctccgcctgg
    13681 accggcagct ctgcttctcg ctgaacgccg cctcccgcgc gttcggcgcc gtctatcgca
    13741 cgctgctcaa ggacctgggc ctcacctacc cgcagtacct ggtgatgatg gtcctctggg
    13801 agcacaccga gctgcccgtg aagcggctgg gcgagctcct gcgcctggac tccgggacgc
    13861 tctccccgct cctcaagcgc ctggaggcgg ccgggctcgt gcaccgcgag cgcagcgcgc
    13921 aggacgagcg atccgtcctc gtccgcctca ccccggcggg caccgcgctg cgcgaggaag
    13981 cggccctcgt gccggtccgg atcgcgacgg ccacgggctt caccgcccag gaggccgggg
    14041 aactgcgcgc gcttctggag aagttgacgc tcgcgctcga cggcgcggcc ttcgacgacg
    14101 gatccctctg cgactgactc gccgcgccgc cggacatgcc cgtgcccggc cggagccggg
    14161 tacgggcagc gcggatcagt cccgcgatgt ggtggtgctc agagtggcga agaggccctg
    14221 gacgcgggtg ccgtcctgga ggttccacca gcccaggacg tgaccggtcg cgccctcggg
    14281 tgcggtgtcc gggccggggc gcagcacccg gtgcagacgg agcgcggcgc catggggcgc
    14341 gcccgtcagc tcggtggact ccgtgtcgtc ggtgacggag gtgaaggccg cggccacggg
    14401 gccctgcccg gtgaaggagc gggcgatccc ctcgtcgagg gtgtcgctga cactctgggc
    14461 ctgggcctgg acccggccct cgatcagggc gaggatcgcc gtggtgaaca ccgggtcgtg
    14521 gcacccgtcg tagacccagc gcttgcccag cacaccgtgc tccagggtcc cgacgagggc
    14581 atcctccgcg ccctccagcg gggcgccccg gtaggtgagc ggcaccaggt agctgaccgg
    14641 ctccgggccc gccgtgtcgg tcgtcaccat gaactcgatc ccgacctcgc cggccgggtc
    14701 gtccagccgg aacccgcccg ccttggtcaa ctgcggcgcg cccgccccgg ggcggtacca
    14761 cggccgggag ggcagccagg aggcgagcag ctcctccttg gtgggcgtaa gggtggtgcg
    14821 gtggatgacg gacataccct ggcttctctt tcgttgagcg ttgtatgacc cctcatcatg
    14881 ggcgagatca gtcgtcgacc ggaagcccct gcggctcctt gacccgcttc atgatgatct
    14941 gcgagttgac ctcggtgatg cccgacagcg tggtgaggcg ctcgatccac agccgctcgt
    15001 aggccgtgag gtcggcgacc gcgatgcgca gcagacagcc cgggctgccg aagagccggt
    15061 acgcctcgat cacgtccggg atgccctgga gcgcggcctc gaacgcctcg accgcctccc
    15121 ggtcgcgctt gacctcgatg gagacgagca cctcgaagcc ccgcccgacg gcctccgggt
    15181 tgatcaccgc ccggtagccc tggatcacgc cgtcctgttc cagctggcgg acacggcgca
    15241 tacaggggga cgaggtgaga cccacgcgct gggcgaggtc ctggatggtc agccggccgt
    15301 ccttctggag ctcgcgcaag atattcctgt cgatctggtc catcacgcga ttatccacca
    15361 cgctacgcgc gtcaccacgc ccgacatggc aaaccgattg cgcccgattc gtcatatcgt
    15421 tgccaggaac aaaccggcgt gcgcccccgg cgcgcacgcc ggtcatgaac tacgagcaga
    15481 agtgagcacg acgtgggaca ggtcgtcgtc atcagcaccg gcggaacgat cgccagccgc
    15541 tggcaggggt ccggcttcgc cgccgacgcc cgcggcgggg acgtcctggc gacggccgcc
    15601 gtgcccgacg gcgtgaccgt gcgggtcgtg gacctgatga gcgtcaacag cgcccggctg
    15661 accaccgccg accagctcgc gctgctgcgc acggtgcacg aggtgctggc cgaccccgac
    15721 gtggccggca tcgtcgtcac ccacggcacg gacaccctgg aggagtccgc cttcttcgtg
    15781 gacctccacc acggcgaccc ccgcccggtg gtcttcaccg gcgcccagct gccgctcgag
    15841 gaccccaacg gcgacgggcc gcgcaacctc cacgacgccc tcctgaccgc cgcctcggtg
    15901 cgcgatctcg gtgtgctcgt cgtcttcgac ggccaggtgc acgccgcgcg cggcacgatc
    15961 aaggtccaga ccctggccgc cgacgccttc gccgacccgt ccgggagccg cgtcgccgac
    16021 gtgggcccca gcggcgtcgt catccaccgg cggcccgagc gcccggagcc tctcccgctg
    16081 cccgcggcgg acgggccgct gccccgggtc gacgtcgtca tgcaccactg cgacgcggac
    16141 accctcctgt tcgacgccgc cgtcggcgcg ggcgcccagg gcgtcgtcct cgtggcgacc
    16201 ggcgcgggca acgccacccc cgagatcgcc gccgccgtcg ccggcgcggc ctcgcgcggt
    16261 gtgctcgtcg ccgtgaccac gcgcgtgccc agcggctccg tcgccgagat ctacacccac
    16321 ggcggcgccg tggacctcgt cgccggcgga gccgtgctca ccggcacgct gcgcgccggc
    16381 caggcacgca tagccgtgct cgccgcgacg ctcgccgcca ccgacccggc cgcgcgcgcc
    16441 gaggcgctgc gccgggccct cggggccccc gcgccggccg ccgacgcgca cggcgcgtcg
    16501 ctcgcgaacg cctgatcacc ccccacaccg cctccccccg cacccgatcg gacccccgat
    16561 gacggccacc gtcccccacc ccgccaccgc acccgacagc accctgttcc gcagcgagca
    16621 cgacctcctc ggcgaccggg acgtccccgc ccacgcgtac tacggcgtcc acacgctgcg
    16681 ggccgtggag aacttcccca tcaccggcac cccgatcgcc gcgtaccccg acctcgtcac
    16741 cgcgctggcc gccgtcaagc aggccgccgc gctggccaac cgcgacctgg gcctgctgcc
    16801 cggcgacaag gcggacgcca tcgtgcgggc ctgcgaggag atccgcgccg gccgcctcca
    16861 cgaccacttc gtcgtggacg tgatccaggg cggcgcgggc acctccacca acatgaacgc
    16921 caacgaggtc atcgccaacc gggcgctgga gcacctcggc cacgccaagg gcgactaccg
    16981 ccgcctccac ccgctggagg acgtcaacgc cgggcagagc accaacgacg tctaccccac
    17041 cgccgtccgg ctctccctcc agctcgccgc cgacgggctg ctggaggcca tggaggtcct
    17101 ccggctggcc ttcgccgcca aggcggagga gttcgcggac gtcctcaaga tgggccgcac
    17161 ccagctccag gacgcggtgc ccatgacgct gggccaggag ttcgccgcct acgccgtcat
    17221 gctggccgag gaccgggccc ggctggagga ggcccgcgcc ctgctccggg agatcaacct
    17281 cggtggcacc gccatcggca ccggcctcaa cgcccacccc gagtacccgg agctcgcgtg
    17341 ccgccacctc ggcgcgatca cgggcgtccc gctgagcgtc gccggcgacc tcgtcgaggc
    17401 cacccaggac atgggcgcgt tcgtccagct gtccggtgtg ctcaagcgga tcgccgtcaa
    17461 gctctccaag acctgcaacg acctgcggct gctctcctgc ggcccgcgcg ccggtctcgc
    17521 cgagatcaac ctgccggccg tgcaggcggg ttcgagcatc atgcccggca aggtcaaccc
    17581 ggtgatcccc gaggtcgtca accaggtcgc cttcgaggtc atcggcaacg acgtgaccgt
    17641 caccatggcc gccgagtccg gccagctcca gctcaacgcc ttcgagccgg tcatcgcgca
    17701 cagcctcctg aagagcatcg cccacctgcg gtccggctgc ctgacgctgg ccgagcggtg
    17761 cgtcaccggc atcaccgcca accgcgagca cctggcccag ctggtcggtc agtccatcgg
    17821 cctggccacc gccctcaacc cgcacatcgg ctacgagaag gccacggccg tcgcccagga
    17881 ggccctgacc accggcgcct ccgtccgcga cctcgtcctg gccaagggcc tgctcacccc
    17941 ggagcggctc gaggagatcc tccacccgga caacctcgcc cgcccccact ccgcggcggt
    18001 ccacggctga ccgccggacc actccgcacc gctcccctcc caagaaacag aaagaagaag
    18061 tacccccatg gcaacggcgc ccagcgtctc gtactcgatg acggtccggc tggaggttcc
    18121 cgcgtcgggg accgcggtca gtgagctgac cacggccgtg gagtcctccg gcgggtccgt
    18181 gaccggcctg gacgtgaccg cttccggcca cgagaagctg cgcatcgacg tcaccatggc
    18241 caccacctcg accgagcacg ccgacgagat cgtcgaaaag ctccgcggca tcgagggcgt
    18301 gaccctgggc aaggtctccg accgcacgtt cctgatgcac ctcggcggca agatcgagat
    18361 ggcctccaag caccccatcc gcaaccgcga cgacctctcc atggtctaca cccccggcgt
    18421 cgcccgcgtc tgcatggcca tcgccgagaa ccccgaggac gcccgccgcc tgaccatcaa
    18481 gcgcaacagc gtcgccgtcg tcaccgacgg ctccgccgtc ctcggcctgg gcaacatcgg
    18541 ccccaaggcc gccctcccgg tcatggaggg caaggccgcc ctcttcaagc gcttcgccgg
    18601 catcgacgcc tggccgatct gcctggacac ccaggactcc gacgccatcg tcgagatcgt
    18661 caaggccatc gcccccggct tcgccggcat caacctcgag gacatctccg ccccccgctg
    18721 cttcgagatc gaagcccgcc tgcgcgaagc cctcgacatc cccgtcttcc acgacgacca
    18781 gcacggcacc gccatcgtcg tcctcgccgc cctgaccaac gccctgcgcg tcgtcggcaa
    18841 gaacgtaggc gacgtccgcg tcgtcatgtc gggtgcgggc gcggccggca ccgccatcct
    18901 caagctcctc atcgccgccg gggtgcggca cgcggtggtc gccgacatcc acggcgtcgt
    18961 ccacaccggc cgccccgacc tcgtctccgc gagcccggac tcggcgctgc gctggatcgc
    19021 ggacaacacc aaccccgagg gcgtgaccgg gacgctgaag gaggccgtgc gcggcgcgga
    19081 cgtcttcatc ggcgtctccg cccccaacgt cctggacggc gaggacgtcg ccgcgatggc
    19141 cccggactcg atcgtcttcg cgctggccaa ccccgacccc gaggtcgacc ccggcatcgc
    19201 ccgcaagacc gccgcggtgg tggccaccgg ccgctcggac ttcccgaacc agatcaacaa
    19261 cgtgctggtc ttccccggcg tcttccgcgg cctgctcgac gcccagtccc gcaccgtcaa
    19321 caccgacatg atgctcgccg ccgcccgcgc cctcgccgac gtcgtcgccg aggacgaact
    19381 caacgccaac tacatcatcc ccagcgtctt caacgcgaag gcgaccgagg cagtggcctc
    19441 ggccgtcaag caggcggcgc tggccgcccg ccagtaggcg gaaatcacgc ggcggtgccc
    19501 gggacacggg caccgccgtt ctcgtacgct cgcccgcgcg cgagcggccc cgcgtcctcg
    19561 gagcggagcg gtcccgggcc ctggccgtgt gggcagggcc cgggaccggg tcagcgggtc
    19621 aggcctccac tccgtagtac tgggcgagga agccggtgac gtccgccgcg tgggggctca
    19681 gctcgggcag gtgcgtggcg agggcggtgc gcacggcctc cgtgagttcg ggcaggccgg
    19741 tggccgcgcc cttgacgtac gggtcgaggc ggcggacgag ctcgtagttg ctctccacgt
    19801 ccagctgccg catggcccgc tccagcggcg gggcctccgc cccggccacc ggcggcagca
    19861 gccggctgac gaacgtgacg cggtgcatca cgcgccagca cgggggcttc cggtccgact
    19921 ggcgcgcctg gcgcagcgcg gccgcgttgg ggtcggtgcc gttctccagc caggtggggt
    19981 cgacgacctt gtggaagaag gtgtcgaagt gctcggtgtc ctcgccgagg tagaagctga
    20041 ggaaccggta ggcgtccacc ttgccgggcg cgttgacggg gttgccgtcg gcgtcgaaga
    20101 cgggtttgcg gttggcgtcg tactgctgga cgttgccgga cggtgagcag gtgacgttca
    20161 gcccgaagga gcgggtggcc tccttgccgc gggcccgggt gacggacatg ccgccgccga
    20221 cggccgcgtc gagctgggcg ttgatcccga cgcccatgat gtcgaaggac gtgccgacgg
    20281 acgcgcccac cgaaccggac agcgagtacg agccggaggt cgtctcgctg acggcgtccg
    20341 tggtctcggt ggtctcggcg aagaagccgc cgtcggcggt ccagacgtag gtgttgacca
    20401 ggtcgcggcg ggagaagccg tcgccggtgg agttgcccgc cgtgtcgcgg cccttgccgg
    20461 gcgaggtgtc gccgccgatc gcgccgccca ggacccggcc cgcccgctcg gcggtggggt
    20521 cgggggcgct cgtgtcggtg gagaccgtct cgtagtagcc gcgcagccgc tgctgctcgc
    20581 gctggatgcg ccgcttgacg gcgtaggcct cgcgaggctt gtagtagctg tactcgccgt
    20641 ggtcgcgggc gtccgtgtag tcggggtcga ggaccttgcc gcgctcgtcg tagccgaccg
    20701 tgccgtccag ggtgccctgt ttggtgtagc gcgggttgag cgggaaggtg acgacgttcc
    20761 agtccttggg gatgtcgggg ttgggctgga tgcggtaggc gacgagggcg ccgctgtggg
    20821 cgagccgcag cgcgaagacg tcggcggtct gggactggac gagcgcgaag ccggtgttga
    20881 cggggatgta ccggcggccg agcgtggcgt tgaggggctt ggtcgggtcc tcccagctgc
    20941 cggagaggtc gaccttcatg gaccgggtgg tgttctcgcc ctgggagacg gcggtctcgt
    21001 cggcccagct gttggagaac tccaggctgc cgcgcacacc cgccgacacc ttggccttcg
    21061 ccatcgactt ggcgacaccg aagcccagcg gtgcggcgat catccacatg tcgacgtcga
    21121 cctcgttgga gagggcgaag gagaacgcgg cgtcgacgct gcgttccttg gccgacgaca
    21181 gcgagtggac gacctcctcg gcctgggtga actccaccga ggcgacgccg tcgtag
//
