LOCUS       NZ_CP034587            22700 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces luteoverticillatus strain CGMCC 15060 chromosome,
            complete genome.
ACCESSION   NZ_CP034587
VERSION     NZ_CP034587.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces luteoverticillatus
  ORGANISM  Streptomyces luteoverticillatus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     The whole draft genome of Streptomyce luteoverticillatus CGMCC 15060
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7367863)
  AUTHORS   Feng,Z., Chen,G., Zhang,J., Zhu,H., Yu,X., Zhang,W. and Zhang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2018) School of Life Sciences, Ludong University,
            186 Hongqi Road, Zhifu Distric, Yantai, Shandong 264025, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 247.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003970715.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:34:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,575
            CDSs (total)                      :: 6,474
            Genes (coding)                    :: 6,276
            CDSs (with protein)               :: 6,276
            Genes (RNA)                       :: 101
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 77
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 104 of 198
            Pseudo Genes (incomplete)         :: 118 of 198
            Pseudo Genes (internal stop)      :: 12 of 198
            Pseudo Genes (multiple problems)  :: 30 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:02:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 81347
            Orig. end                         :: 104047
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034587.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22700
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="2"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22700
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22700
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12700](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12700)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    complement(166..179)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.24"
                     /tool="antismash"
     misc_feature    complement(174..187)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.24"
                     /tool="antismash"
     misc_feature    complement(183..196)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.75"
                     /tool="antismash"
     misc_feature    187..200
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.19"
                     /tool="antismash"
     gene            220..1644
                     /locus_tag="EKH77_RS00395"
                     /old_locus_tag="EKH77_00395"
     CDS             220..1644
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /GO_process="GO:0009410 - response to xenobiotic stimulus
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980738.1"
                     /locus_tag="EKH77_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00395"
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="WP_206279783.1"
                     /transl_table=11
                     /translation="MTSELPSSRRWLVLGICCSALLLVSLDNTILNVALPSLRKDLGAS
                     VSGLQWTIDAYVVVLASLFMLAGSTADRFGRRRVFVTGLALFTAGSALCSLAPGLGWLI
                     AFRAVQAVGGSMLNPVAMSIITNAFTRPAERARAIGVWGGVVGISMAAGPIIGGTLVES
                     VGWRSIFWINVPVGLAALVMTLRYVPESRAPRPRRFDPAGQLLMIVLLASLTYGIIEGR
                     AAGWGSPEIVGCFTLSVAALAALIVHENRRFEPLIEPRLFRSAPLAGATATAVCAFAAL
                     SGFLFLNMLHLQERRGLSALDAGVHMLPMAAMCLVFAPLSGRLVGARGPRLPLVLAGVT
                     LTASGVLFAAFEAESSDPLLFTAYVLFGIGFGLVNAPITNTAVSGLPHSRAGVAAALAS
                     TSRQVGTSLGVAVIGATAAAGTGVTGWWIVTGCGLAVLTLGTITTGRWAARTAERAATG
                     LDRNSPDRTRTSVTTP"
     gene            1641..2078
                     /locus_tag="EKH77_RS00400"
                     /old_locus_tag="EKH77_00400"
     CDS             1641..2078
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556668.1"
                     /locus_tag="EKH77_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00400"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_126912447.1"
                     /transl_table=11
                     /translation="MSTQDETARRAWDNLREIVLGGNERRKEVVEALGMSFIRIKALRR
                     IAKRPMTLRELAEELLTDRPYTTLVVDDLARQGLVERSENPSDRRSKIVSLTPEGRAAA
                     ERADAIIGKPPAALLALPDEDLAALERIAGRVAKLTADQRR"
     gene            2133..2696
                     /locus_tag="EKH77_RS00405"
                     /old_locus_tag="EKH77_00405"
     CDS             2133..2696
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187898.1"
                     /locus_tag="EKH77_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00405"
                     /product="hypothetical protein"
                     /protein_id="WP_126912448.1"
                     /transl_table=11
                     /translation="MDLTPYVDDLHRQLAVAAEAGGEETRALAERLTAPLESAARLTLL
                     NALSAAMDEVTRDLAPGSVDVRLRGLDPEFVVTPPPVPEAFEDGLARGGDMGGGHGPAP
                     LPPAPAAATMSAEGDEGGTARINFRLPAPLKARVEDAAGREGLSVNAWLVRAVAAALEP
                     AGGHARPAGRTRHGNSQGFTGWVR"
     gene            2763..3599
                     /locus_tag="EKH77_RS00410"
                     /old_locus_tag="EKH77_00410"
     CDS             2763..3599
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006125606.1"
                     /locus_tag="EKH77_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00410"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_126912449.1"
                     /transl_table=11
                     /translation="MPVFDTPEPIAVTVEFEVGTTRVSASERTDTVVEIRPANSASDTD
                     VRAAQQTDVTYANGKLSVKGPRKRSPFGRPGSLEVSIELPSGSQLQAASPLGDFLCEGP
                     LGDCRLKTSAGDIRVEEAATVVLKTSHGDIHLGRATGDAEIIGAGRVEAGRLGGAATVK
                     NVNGGTTIDEAVGHVKAHASNGRISIGVAHTSVDARSANGAIRIDEVVSGRVTLATSAG
                     DLEVGVRESTAAWLDVKTNLGAVRNDLTPSDSPEGAAETVEVRARTAMGDITIRRP"
     gene            complement(3621..4283)
                     /locus_tag="EKH77_RS00415"
                     /old_locus_tag="EKH77_00415"
     CDS             complement(3621..4283)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010045164.1"
                     /locus_tag="EKH77_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00415"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_126912450.1"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-23, bitscore: 81.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFPIDALLFDSDDTVVSTRSVARSVWRQWAESHGMNLEEVMARV
                     PVHGRPAKAIIADLLPADQVAEAVRRLEDAEVAHARAGNVTAVPGAPELTASLPAHRWA
                     VVTSGARRVARARLGHLGMLPEVLVTSDDTTRHKPHPEPFLLAAARLGVDPSRCAVVED
                     APAGLAAGRAAGMTTIALTTTHTAEELEADVIVEDLTALSAHVTHDGRLEVEIAVRV"
     misc_feature    complement(4257..4259)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4350..7073)
                     /locus_tag="EKH77_RS00420"
                     /old_locus_tag="EKH77_00420"
     CDS             complement(4350..7073)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_00420"
                     /product="hypothetical protein"
                     /protein_id="WP_126912451.1"
                     /transl_table=11
                     /translation="MADGQPGGDVNNIFQGTADIVIQFRDNFGEIHVHAPPSATPSEKS
                     AHALAEAVYRQWREEAKAWDVGGDRAAMAVRWAPRRRRADHAAHTGGDVRGRADQLTDL
                     LTGFLALPKRRLALLGAAGSGKTTLAVLLTMELLRRRLAGRVGDASTESLPVPVLLSLT
                     SWDPDREEFGAWFTRRLAEDHPGLPRIGGRHPARELWSTSGSVLLPVLDGLDEMPGARR
                     SAAVKALNRALYDRPLIITSRTAEFDALSPETVLGHTAVIEARPVTATAAVAYLNSAAP
                     NASPRWEPVFAEVRERPDGPLAGALSTPLMLSLARTVYARPWSEPVELTDRVRFPSRRS
                     VEDHLLDQFVPSVFTGEIPSDDRLDPPRRWSPSHARRYLGALARHLQAQETTELAWWRL
                     HRTPAARLAAFPALVLLGVVLSALATGLGRRVREASGGGTGPWGALTSMQLSTALFAGV
                     VTGMATQMLVRTWYTDHRFGEPRRTVSLRRPVAAARSAWRHTTRLRALSAALLAVPIAA
                     GFEAPVLHTATPGLYWLGAGCVAAAFAVAVLFTAPSDADENATTPRALLRAEHAAVTRA
                     LFVIGPLFGVASGVLHYGPDDMSMAYAAGLVTWLGAAGMLILISPWSRWALARTTLALT
                     GQAPWALMRFLQDAHRQGVLRQVAGTYQFRNAWLQERLAISTSTGLRNRSTSLYDERLL
                     AEDGITATSDGGWAFRLNVRRGTLAPIKAALPPAALFTLSVALRNGASEPARLCAPAAL
                     FLGIGGILSGLSWLLPRRVADLRISPHRISCLTPPKREVRFDWTHVAEVTVRRSRGRNA
                     ETGTYGIHVRLHPDAPHGLRSPKDKGAWRLVCDIGRRPVLPPAVEEALRDCAAERWVPP
                     AFPSVPGDGPRPRATNADDTRNDFTQWEKEFGPSGS"
     misc_feature    complement(7031..7045)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.74"
                     /tool="antismash"
     gene            complement(7211..8530)
                     /locus_tag="EKH77_RS00425"
                     /old_locus_tag="EKH77_00425"
     CDS             complement(7211..8530)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007493290.1"
                     /locus_tag="EKH77_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00425"
                     /product="acylglycerol kinase family protein"
                     /protein_id="WP_126912452.1"
                     /transl_table=11
                     /translation="MDGAPDPHETIRRRRFARLAIAAAGTGILLLVIAGPRSLLLLGVG
                     AAALLAFVMGLWWTAARRGPVRILAAGLAVAAPVAAIVLYTAAGLLWLVLLCLVLWAGA
                     ASAGWTALGAGSPSTTAREHPAAPPSRPYLIMNPRSGGGKVEEFGLREKAEALGARVVL
                     LDPDGGQDVAALARRAAADGADLLGVAGGDGTQALVADVAAAHGLPFMVLPAGTRNHFA
                     LDLGLDRDDPVACLNALTDGVELRVDLGRVGDRAFVNNASFGAYATIVRSRAYRDDKIR
                     TILRLLPDALSRHTGPHLRVHAGGDTIDAPQAVLVSNNPYRVGDSAGLGRRDRLDGGVL
                     GLLGVKVDTAAQAADLLLAPDSPGLTLLTTHEAVIEADTPEVSVGVDGEALALPAPVRC
                     AIEPGALRVRVPRRRPGVPRAKPRLDWRRLYAMATTTGRP"
     gene            complement(8681..9775)
                     /locus_tag="EKH77_RS00430"
                     /old_locus_tag="EKH77_00430"
     CDS             complement(8681..9775)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="EKH77_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00430"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_126912453.1"
                     /sec_met_domain="LANC_like (E-value: 2.1e-43, bitscore:
                     147.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGAPGRPWRPLLSPATAATTLARVLSAARPHRVPRRVRPHLAAG
                     AAGLALAYHQLDRCLPGRGWKTLAEDYLAAVAREYERTGASAGLFGGAAGLALAARVLG
                     HDLPTAHTHVVTEASRRAKELGDDPPERALDLVSGLTGAGAHLLGRHHEPASLAALRDV
                     LTALTTAASRRPPPDCGVAHGVSGPLALLALALGEGVTVPGQREAVAGYTALLTERRAD
                     DPWGPNWTGPATGTPVRASWCRGSPGIARALWLAGTALGDTAPRELAVRALKAVHRRPA
                     AARRIDVDPGLCHGLAGLLHITARFAHDTGDPELTTAVEGLATARFPRADDPGFLDGAA
                     GVALALLAAATDTEPTWDRALLLA"
     gene            complement(9864..9995)
                     /locus_tag="EKH77_RS34240"
     CDS             complement(9864..9995)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS34240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268248359.1"
                     /transl_table=11
                     /translation="MEDMVLELQELPETDEQALEPAMCCDTDHTSGQCTEIGPRCKG"
     CDS_motif       complement(9927..9995)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEDMVLELQELPETDEQALEPAM"
                     /locus_tag="EKH77_RS34240_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9864..9926)
                     /prepeptide="core"
                     /locus_tag="EKH77_RS34240_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.10"
                     /molecular_weight="2039.2"
                     /monoisotopic_mass="2037.8"
                     /core_sequence="CCDTDHTSGQCTEIGPRCKG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEDMVLELQELPETDEQALEPAM"
                     /leader_location="[9926:9995](-)"
     gene            complement(10001..12700)
                     /gene="lanL"
                     /locus_tag="EKH77_RS00435"
                     /old_locus_tag="EKH77_00435"
     CDS             complement(10001..12700)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="EKH77_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00435"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_240667145.1"
                     /sec_met_domain="Pkinase (E-value: 1e-17, bitscore: 62.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.6e-41, bitscore:
                     140.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVGPRASYQSIATRILGAERSAWSMRNGETWCALAPPGYRPRRQ
                     GWKLHVSATVASAHQVLEHAARVLVAHGCAFKFAVSPRVTADLTSVRAPRPHSGKFLTA
                     YPADDEQLRTLAEELHRATLGLAGPVILSDRRYRPGSLVHYRYGCFSPPRELDDEGFYR
                     GRLQAPDGTYVTDERNPWFSPPAWARPPFDDVPERPRSRGGPVLLADRYLVHEAIRHSN
                     RGGVYRARDRHTGRDVLLKEARPHVGAQPGGTDARDRLRHEAEVLSLLAPHGVAPAPHG
                     VFEAGGHVFLAEDLIDGENLQQWSADRASRHGGRLPVADARRLARDLTRLIGVVHAAGF
                     VLRDLKPTNVLVRPDGTPVLVDLEGAVRTGDTAPVLGTQGFTAPEYLSRTEAGPAPGPE
                     ADCYSLGVTLLHATAGINPVLAPDTPPARPPGERLATLVAAAAPDCPALRALAPLVLGL
                     IADPPARRPLEAAATFLRAEPATPPPTPSPALTGPDLDRLLGDGLAHIAATVDPDPTAE
                     HLWPRPASLPEGDPCNLQQGAAGVLAVLDRAVRTGEAPALAPLLRTATHWIDARLALPG
                     RTLPGLYFGRSGTVWALHDAARTLDDPGLAARARQYALDIPLDRADPDVCHGLSGAGLA
                     QLRLWRTTGDERFAERASACADSVIRLTAEADRAGGGVDWPLGPPHRRELAGSGSYGFG
                     HGVAGHAAFLLAAGSELDRPELADIAIGGGHALCALAERRGDIAVWPKGPGRTERMGLD
                     FWCNGASGIGTTLIRLWQATGEPRFREHAELAARAAHRDRWRLGTGTCHGVAGNAQLLL
                     DLADATGDDTYRTRAAEAAYCLHARAARRDGRLVVPDDTLRDFCVSYHVGLAGALDLLL
                     RLKHGGGRPWTADRTDHTSPAPDRPERR"
     misc_feature    complement(12874..12887)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.52"
                     /tool="antismash"
     misc_feature    complement(12891..12908)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.46"
                     /tool="antismash"
     misc_feature    complement(12903..12912)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.81"
                     /tool="antismash"
     misc_feature    12921..12936
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.72"
                     /tool="antismash"
     misc_feature    12921..12936
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.17"
                     /tool="antismash"
     gene            12997..14274
                     /locus_tag="EKH77_RS00440"
                     /old_locus_tag="EKH77_00440"
     CDS             12997..14274
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173109.1"
                     /locus_tag="EKH77_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00440"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_240667678.1"
                     /transl_table=11
                     /translation="MVALGFLIALEIVARRYAGVPGPITNQAKEVIFAPKPGPLYGGLA
                     LMMVVLTWRQRFIAAGAAVGIDVVFVLVRWAVGADMSDGRYFGNGALWVMLGCAVIAVT
                     RRTGRERVLLLQGVGLGLLLVAGRKTGDTWLLITSKTRPTVLDQYVATADHALGNPSWL
                     AGRILKATGPVGIHVLDLVYAQLAVAAVAVALYQLRNVATERRFPSHHLVRTFLVIGLL
                     GPAIYMIFPVVGPIFAYGPGTSGTGGLQWAVADLWPHTPPAIGVPHPVPYDGITPRNCM
                     PSLHTAWATAIFIHSRKGPRALRYAGTFWLVATLSATLGFGYHYGADLIAGVVFSLTIE
                     AGLRSLDRGWDRSGTRLVAYGATVFTVLLLSYRYLPVEMAGHPWLSGPLLVLAMGSVIY
                     GYVRTTRSWEPKAAPARRPEPQLELV"
     gene            complement(14350..14553)
                     /locus_tag="EKH77_RS00445"
                     /old_locus_tag="EKH77_00445"
     CDS             complement(14350..14553)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_00445"
                     /product="hypothetical protein"
                     /protein_id="WP_126912454.1"
                     /transl_table=11
                     /translation="MVGLPKWGNKESRAAEHERKQREKQEKKERAAVKAKEAEKTTEGG
                     YKPAPEEDVLGWGHRGESSPHQ"
     gene            14683..15834
                     /locus_tag="EKH77_RS00450"
                     /old_locus_tag="EKH77_00450"
     CDS             14683..15834
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020548967.1"
                     /locus_tag="EKH77_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00450"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_126912455.1"
                     /transl_table=11
                     /translation="MGSLSRSDPRPGPGVHGGLFRLGQCVPFAIALLVLGIEFSPAHFL
                     YTGPLLTATPALAAVTMGPRGTVAAAAVAMAVSATTATYNHAWGSLQVLTNFLALFLVS
                     GAGFLTSRAVRTRRRNEIDQVRRIATAAQQVILRPVPARLGPVGAAGMYLAAEAGAQIG
                     GDLYEITETRYGVRVIIGDVRGKGLPAVRSAAAVLGAFREASHYEEDLVEVMNHCTAAL
                     RRESAVPGAYSEDTLLEGFVTALVAQVSEGPAEEPVVEVVNRGHPPPLVLSRGEVRALT
                     PSSPLPPLWLEDFMTGPPAAAESHPFAVGDRLLLYTDGVIEARDGDDRFFPLAEAMERV
                     AEGTTPADAPRDFLEQLHRRLVLHTRGRLADDAAMLLVDRLER"
     gene            complement(15844..16164)
                     /locus_tag="EKH77_RS00455"
                     /old_locus_tag="EKH77_00455"
     CDS             complement(15844..16164)
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_00455"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_240667146.1"
                     /transl_table=11
                     /translation="MIDLRHPWEVERSGRLPHHPSLAYHNLSIEHRPYDQAALGPDVEP
                     ARYPPHLTLGWPAYGRAPAGIMSLFMAELAARYGSVRGYAAQRLGVDDELVSTLRGQLL
                     TP"
     misc_feature    complement(16135..16150)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.0"
                     /tool="antismash"
     misc_feature    complement(16150..16165)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            16315..16725
                     /locus_tag="EKH77_RS00460"
                     /old_locus_tag="EKH77_00460"
     CDS             16315..16725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849671.1"
                     /locus_tag="EKH77_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00460"
                     /product="DUF1992 domain-containing protein"
                     /protein_id="WP_126912456.1"
                     /transl_table=11
                     /translation="MTDRKPRVSDFESWADKQIREAEERGDFRDLPGFGRPLAGIDRPY
                     DADWWVKDKMRRENLSFLPPTLALRKEAEDALAAAVAARSEEEARRIVHEINDKIAASL
                     RRPPPGPPLGLVPFVIDDVLAARREKRGDGRP"
     gene            16795..17259
                     /locus_tag="EKH77_RS00465"
                     /old_locus_tag="EKH77_00465"
     CDS             16795..17259
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_00465"
                     /product="hypothetical protein"
                     /protein_id="WP_126912457.1"
                     /transl_table=11
                     /translation="MSDQEETLRKIITGVALALTAALLTGCGSGDSSPAAADKPATSAQ
                     PKAKAEGGSGEVKHEVTLEVLGSETTSVYYNLDTNKMEQVQLPWKKTSTITLTTDAEKK
                     VGLLVSVVPGSVHGPDGMLHAAPCVITVDGKKVADNQDGKSDKMCEYKVK"
     gene            17375..18301
                     /locus_tag="EKH77_RS00470"
                     /old_locus_tag="EKH77_00470"
     CDS             17375..18301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104584.1"
                     /locus_tag="EKH77_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00470"
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="WP_126912458.1"
                     /transl_table=11
                     /translation="MAEESAREPLIVSDEVREALDLGRPVVALESTIIAHGLPRPRNLR
                     VAEELEELVRAGGAVPATVAVLDGRPHVGLDKARLARVAGEDGLRKLGSRDLAPAVAAG
                     ASGATTVSGTAFLAERAGIRVFATGGLGGVHREWAQTQDESADLRLLARTRIAVVCAGV
                     KSVLDVPATLQRLETLGVGVLGFRTREFPGFYLTGSGVPVDWTVGTAAEVADVLRAQDA
                     LGGPPSALVVANPVPVDQQLDPALHDRVLAGALAACAREGVTGQAVTPFLLDHLFRHTD
                     GASLEANVAAVRGNVRLAAEIAKAYAA"
     gene            18298..19230
                     /locus_tag="EKH77_RS00475"
                     /old_locus_tag="EKH77_00475"
     CDS             18298..19230
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989495.1"
                     /locus_tag="EKH77_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00475"
                     /product="sugar kinase"
                     /protein_id="WP_126912459.1"
                     /transl_table=11
                     /translation="MTGGGPGGGSEGGSRGLLVVGDVVTDIVARHRSPLAPATDTAARI
                     ASLPGGAGANVACWAARSGAEDVRILARVGADAVDAHERVLRAAGVRPRLVADPAAPTG
                     TVICLVGADGERTFLTDSGAVLRLSTADWDGELLAGVGHLHVSGYLFFADASRAAARLA
                     MEAARARSIPVSVDPASAGFIAGFGTDRFLAALAGVDVLLPSHHEAALLTGRSEPAEAA
                     AELSRRFPLVVSTRGARGALVAASGAIVARVPARPATAVDTTGAGDAFTGGFLAARLAG
                     HGPVEAARHGCRTAAEAVTVIGGRPRDPG"
     gene            19309..20085
                     /locus_tag="EKH77_RS00480"
                     /old_locus_tag="EKH77_00480"
     CDS             19309..20085
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561662.1"
                     /locus_tag="EKH77_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00480"
                     /product="N-acetyltransferase"
                     /protein_id="WP_126912460.1"
                     /transl_table=11
                     /translation="MRDIDSITITTLAERPALIPRIYEIDDTWPYFTAHEPVVGALLGR
                     VPEDFPDYCVVATDATDGDRVVARGLSVPFNASLDGREETPDQGWDRVLVWASDDRLRG
                     VAPTTASALEITVDREHLGRGLSSRMLTAMREAVGRQGHDVLLAPVRPTAKHLEPRVPM
                     ADYALRRRDDGLPADPWLRVHVRAGGVIEKVAPASMTVSGSLAEWRRWTGLPFDRDGDV
                     EVPGALTPVRCDVAHDRAVYVEPNVWVRHRAGGRPG"
     misc_feature    19316..19336
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            20216..20623
                     /locus_tag="EKH77_RS00485"
                     /old_locus_tag="EKH77_00485"
     CDS             20216..20623
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327055.1"
                     /locus_tag="EKH77_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00485"
                     /product="ATP-binding protein"
                     /protein_id="WP_126912461.1"
                     /transl_table=11
                     /translation="MMRRVLATAALAMAALGAGAVGPGATAYAAPLPSGLDLKGVTMDP
                     GNLGSAVDEAAQKSTRVIGDAGGGAVGKVVPAAGRTGGTAVKSSTSAVQQTIGRAAGSA
                     GETVGETAKAATKDGPPFGRLAPGRLGHLPS"
     gene            complement(20697..20906)
                     /locus_tag="EKH77_RS00490"
                     /old_locus_tag="EKH77_00490"
     CDS             complement(20697..20906)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EKH77_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EKH77_00490"
                     /product="hypothetical protein"
                     /protein_id="WP_126912462.1"
                     /transl_table=11
                     /translation="MDSSRERDPYRDDGDYVEDMTEETLGQREQSRQSMQGGQQDERRR
                     RLNDDLNDNLSDDRDGLDDLDDLP"
     gene            complement(21006..22109)
                     /locus_tag="EKH77_RS00495"
                     /old_locus_tag="EKH77_00495"
     CDS             complement(21006..22109)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004943703.1"
                     /locus_tag="EKH77_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EKH77_00495"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_126912463.1"
                     /transl_table=11
                     /translation="MSYQSPTTYQARRRPSRAKRWVIAGASVVTLGLIAWPVMSYYEIP
                     PFTDKGDAISFGGSGDGKNGDQAPGSKAQMPLGPKAGFKISGTVPEDGTKIAVTTYKGK
                     KSGFEGKVWVWAPKEYDDPKYAKSGFPVLIALPGGAGYPNNYWMGTDLKLEASISKWAQ
                     EGKSLPFIIAMPVLNPENHDKDPKDPKAGLYWDGSDIPGQPKMGTWLTEDVPQLVKENF
                     RTIKSRDGWAFMGSSTGASAGLKSVLQKPDQFKAVIASGPDIVPDSRLWAGHEKEKADN
                     NSDVLAQRLIAKKGPEVYLAFQVGSNEPVKPPIDRFLAKYGNNKGPIKTKYRINVGGEH
                     NAASYVPNMEAGGLIQWVSEHMQGPTT"
     misc_feature    22213..22228
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.25"
                     /tool="antismash"
ORIGIN
        1 cgccgtcaac gagatcatgg tgcggcccac ggcgcaggag ccctgaccgc cggggccgtc
       61 ccggaaagcg ccgtcgaggg gcgcgcccgg aagggcgcgc ccctcgacgg cgttcttgct
      121 tcagtgagcc ccggcggaaa accagtgcgc cggaccccgc attggttgta ctctttaaat
      181 gattggactt attaaactaa cctgacccgg gaggtcggtg tgacctcgga gttgccctcc
      241 agccgccgtt ggctcgtcct cggcatctgc tgctcggccc tgttgctggt cagcctggac
      301 aacacgatcc tcaatgtggc cctgccctcc ctgcggaagg atctgggtgc ctcggtctcg
      361 gggctccagt ggaccatcga cgcctacgtc gtcgtcctgg cctcgctgtt catgctcgcg
      421 ggctcgacgg ccgaccggtt cggccggcgg cgcgtcttcg tcaccggtct ggcgctgttc
      481 accgccggat cggcactgtg cagtctcgcg cccggcctcg gctggctgat cgccttccgg
      541 gccgttcagg ccgtcggcgg ctccatgctc aaccccgtcg cgatgtcgat catcaccaac
      601 gccttcaccc gccccgcgga acgggcccgg gccatcgggg tctggggcgg ggtcgtgggc
      661 atcagcatgg cggccgggcc catcatcggc ggcaccctgg tggagtcggt cggctggcgc
      721 tcgatcttct ggatcaacgt gcccgtcggg ctggcggcgc tggtgatgac cctgcgctac
      781 gtaccggagt cccgggcccc gcggccgcgc cgcttcgacc cggccgggca gctgctgatg
      841 atcgtgctgc tcgcctcgct gacctacggg atcatcgagg gccgtgcggc gggctggggc
      901 tccccggaga tcgtcgggtg cttcaccctc tccgtagccg ccctcgccgc gctgatcgtc
      961 catgagaacc ggcgcttcga gcccctcatc gaaccccgcc tcttccgcag cgcgccgctg
     1021 gcgggagcca ccgccacggc ggtctgcgcc ttcgcggcgc tgtccggctt cctgttcctc
     1081 aacatgctgc acctccagga acggcgcggt ctgtccgctc tggacgcggg tgtgcacatg
     1141 ctgcccatgg ccgccatgtg cctggtcttc gcgccgctgt ccggacggct ggtgggggcg
     1201 cgcggacccc ggctgccgct cgtcctggcc ggggtgacgc tcaccgccag cggcgtgctc
     1261 ttcgcggcgt tcgaggcgga gtcgtcggac ccgctgctgt tcaccgccta tgtgctcttc
     1321 gggatcgggt tcgggctggt gaacgcgccc atcaccaaca ccgcggtctc cggcctcccg
     1381 cactcgcggg ccggggtggc cgccgcgctg gcgtccacca gccggcaggt cggcacgtcg
     1441 ctcggtgtcg cggtcatcgg cgccacggcc gccgccggta ccggggtcac cggctggtgg
     1501 atcgtcacgg ggtgcggact ggccgtcctc accctcggta cgatcaccac cggccgctgg
     1561 gccgctcgga ccgccgagcg cgccgcgacc ggcctcgacc gcaacagccc cgaccggacc
     1621 aggacctcgg tgacgacccc atgagcacgc aggacgagac agcacgacgg gcctgggaca
     1681 acctccggga gatcgtcctc ggcggcaacg agcgccgcaa ggaggtcgtc gaggcgctcg
     1741 gcatgagctt catccgcatc aaggcgctgc gccggatcgc caaacgcccc atgacgctgc
     1801 gggagctggc ggaggagctg ctgacggacc ggccgtacac gacgctcgtc gtggacgacc
     1861 tggcacggca ggggctggtc gagcgctcgg agaacccctc ggaccggcgc tccaagatcg
     1921 tctccctgac gccggaaggg cgcgccgccg cggaacgggc cgacgccatc atcggcaagc
     1981 cgcccgcggc cctgctggcc ctgccggacg aggacctggc ggcgctggaa cggatcgccg
     2041 ggcgggtggc gaagctgacg gccgatcagc ggcgctgatc gcccgacggg ggggctttgc
     2101 gcatggcgcc atcctggcgc cataatgacg tcatggactt gacgccctat gtcgacgatc
     2161 ttcatcgcca gctcgcggtc gccgcggaag cgggtggtga ggaaacccgg gccctggccg
     2221 agcggctcac cgcgcctctc gagtccgcgg cccggctcac gctgctgaac gcgctctccg
     2281 ccgccatgga cgaggtcacc cgtgacctcg cgcccggttc ggtcgacgta cggctgcgcg
     2341 ggctcgaccc cgagttcgtc gtgacaccgc cgcccgttcc ggaggccttc gaggacggcc
     2401 tcgcgcgcgg cggcgacatg ggcggcggcc atggccccgc cccgctgccc ccggcgcccg
     2461 ccgcggccac gatgtccgcc gagggcgacg aaggcggcac cgcccgtatc aacttccgcc
     2521 ttcccgcgcc cctcaaggcc cgggtcgagg acgccgccgg ccgggagggc ctgtcggtca
     2581 acgcctggct ggtacgggcc gtcgccgcgg ccctcgagcc ggccggcggc catgcccgcc
     2641 ccgccgggcg gacgcgccac gggaactcgc agggcttcac cggctgggtg cgctgaccac
     2701 gccgcgcccc ggtcgttccc cgttcttccc tcatccacca cagccatgag gacggcacag
     2761 ccatgcctgt tttcgacact cccgaaccga tcgccgtgac cgtcgagttc gaggtcggca
     2821 ccactcgggt cagcgcgagc gagcggacgg acaccgtcgt ggagatccgg ccggccaaca
     2881 gtgccagcga caccgacgta cgcgccgcgc agcagaccga cgtgacctac gccaacggta
     2941 agctctcggt caaaggtccc cggaagcgct cgcccttcgg ccggcccggc tcgctggagg
     3001 tgagcatcga gcttccctcg ggctcacagc tgcaggccgc ctctcccctg ggcgacttcc
     3061 tctgcgaggg gccgctcggc gactgccggc tgaagacctc ggcgggcgac atccgcgtcg
     3121 aggaggcggc caccgtcgtc ctcaagacct cccacgggga catccacctc ggccgtgcca
     3181 cgggggacgc cgagatcatc ggggccgggc gcgtcgaggc cggccggctc ggcggcgccg
     3241 cgacggtgaa gaacgtcaac ggcgggacga cgatcgacga ggccgtcggc catgtgaagg
     3301 cccacgcctc caacggacgc atcagcatcg gcgtcgcgca cacgtcggtc gacgcgcgct
     3361 cggccaacgg cgccatccgg atcgacgagg tggtcagcgg ccgggtcacc ctggcgacct
     3421 ccgccgggga cctggaggtc ggcgtccgcg agtccaccgc cgcctggctc gacgtcaaga
     3481 ccaacctcgg cgcggtgcgc aacgacctca ccccctccga cagtcccgaa ggggccgcgg
     3541 agacggtcga ggtccgcgcc cgcaccgcca tgggcgacat caccatccgc cgcccctgac
     3601 cacccgtcgg cccttcgcac tcagactcgt acggcgatct cgacctcgag ccggccgtcg
     3661 tgcgtgacat gggcggagag ggcggtgagg tcctcgacga tcacatccgc ttcgagctct
     3721 tccgccgtgt gcgtggtggt cagggcgatg gtcgtcatgc ctgccgcgcg ccccgcggcc
     3781 agcccggccg gcgcgtcctc gacgacggcg cagcgggacg ggtcgacgcc caggcgcgcg
     3841 gctgccagga ggaagggttc cgggtggggc ttgtggcggg tggtgtcgtc ggaggtgacg
     3901 agcacctcgg gcagcatgcc caggtgcccg agccgggccc gggccacgcg gcgggcgccg
     3961 gaggtcacca cggcccagcg gtgcgcgggc agcgaggccg tgagctcggg cgctccgggg
     4021 accgcggtga cgttgccggc tcgggcgtgg gccacctcgg cgtcctccag gcgccggacc
     4081 gcctcggcca cctggtcggc gggcagcagg tccgcgatga tcgccttggc aggacgcccg
     4141 tgcaccggga cccgtgccat cacctcctca aggttcatgc cgtgggactc cgcccattgc
     4201 ctccatacac tgcgggccac cgagcgcgtg gagacgaccg tgtcatcgct gtcgaataaa
     4261 agggcgtcaa tcggaaatcg catgatccgg agcgtaccgg tgccgttccg gcgcgcagga
     4321 cgcgtcagtc aggggccggt gaagaggatt cagctgccgg acgggccgaa ttccttttcc
     4381 cattgggtga agtcgttcct cgtgtcgtcg gcgttcgtcg cgcgtgggcg ggggccgtcg
     4441 ccggggacgg acgggaaggc gggcggtacc cagcgttccg ccgcgcagtc ccgcagggcc
     4501 tcctcgaccg ccgggggcag gacgggccgg cgtccgatgt cgcagacgag gcgccaggcg
     4561 cccttgtcct tcgggctgcg gaggccgtgc ggcgcgtcgg ggtggaggcg gacgtggatg
     4621 ccgtacgtgc cggtctccgc gtttctgccg cgggatctgc ggacggtgac ttccgcgacg
     4681 tgggtccagt cgaagcggac ttctcgcttc gggggtgtga ggcaggagat ccggtggggt
     4741 gatatccgca ggtcggcgac gcggcggggc aggagccagg acagtccgga gaggatgccg
     4801 ccgatgccga ggaacagggc tgcgggggcg cagagccggg cgggctcgct cgcgccgttg
     4861 cgcagcgcga cgctcagggt gaacagggcc gccggtggca gagccgcctt gatgggggcg
     4921 agggtgcccc tgcggacgtt gagccggaag gcccagccgc cgtcggatgt ggcggtgatg
     4981 ccgtcctccg ccaggagccg ctcgtcgtac agggaggtgg aacggttccg gaggccggtg
     5041 gaggtgctga tcgcgagccg ctcctggagc caggcgttcc ggaactggta ggttcccgcg
     5101 acctggcgca ggacgccctg gcggtgggcg tcctggagga agcgcatcag cgcccagggg
     5161 gcctggccgg tcagtgccag ggtggtccgg gcgagcgccc agcgactcca cgggctgatc
     5221 aggatcagca ttccggccgc gccgagccat gtcaccagcc cggccgcgta ggccatggac
     5281 atgtcgtccg gcccgtagtg gagcacgccg gacgcgacgc cgaacagcgg gccgatgacg
     5341 aacagggccc gggtgacggc tgcgtgttcg gcccgcagca gggcgcgtgg ggtggtcgcg
     5401 ttctcgtcgg cgtcggaggg cgcggtgaag agcacggcga cggcgaacgc cgccgcgacg
     5461 cagccggcgc ccagccagta caggcccggt gtggcggtgt ggagcaccgg tgcttcgaag
     5521 ccggccgcga tggggacggc gagcagggcg gcggacaggg cccggagccg tgtcgtgtgc
     5581 cgccaggcgg aacgcgccgc cgccacgggc cgccgcaggc tcaccgtccg tctcggctcg
     5641 ccgaagcggt gatcggtgta ccaggtccgt acgagcattt gtgtcgccat gccggtcacc
     5701 acgcccgcga acagcgccgt cgagagctgc atcgacgtca gggcccccca tggccccgtg
     5761 ccgccgcccg acgcctcgcg gacgcgccgt ccgaggccgg tggccagggc ggacagcacc
     5821 accccgagga gcacgagggc ggggaaggcg gcgaggcggg cggcgggggt gcggtgcagg
     5881 cgccaccagg cgagttcggt ggtctcctgg gcctgcaagt ggcgggcgag ggcgccgaga
     5941 tagcgtcgcg cgtgggaggg ggaccatcgg cgcggcgggt ccaggcggtc gtcggagggg
     6001 atctcccccg tgaacaccga cgggacgaac tggtccagca ggtggtcctc cacggaccgc
     6061 cgggagggga agcggacccg gtcggtcagt tcgacgggct ccgaccaggg gcgtgcgtag
     6121 accgtccggg ccagggacag catgaggggc gtcgacagcg ccccggccag tggcccgtcg
     6181 ggccgctcgc gcacctccgc gaacaccggc tcccagcgcg gggacgcgtt gggggcggcg
     6241 ctgttgaggt aggcgacggc ggcggtggcc gtgacggggc gcgcctcgat gacggccgtg
     6301 tgcccgagca cggtctccgg ggagagggcg tcgaactcgg cggtgcggga ggtgatgatc
     6361 aggggtctgt cgtacagggc gcggttcagt gccttcacgg ccgccgagcg gcgggcgccg
     6421 ggcatctcgt cgaggccgtc gagcacgggc agcagcacgg acccgctggt gctccacagc
     6481 tcgcgggcgg ggtgccggcc gccgatccgg ggcagtccgg ggtggtcctc ggccagccgg
     6541 cgggtgaacc acgcgccgaa ctcctcgcgg tccgggtccc aggaggtcag cgagaggagg
     6601 accggcacgg ggaggctctc ggtgctcgcg tcgccgactc gtcccgccag ccgccgtctc
     6661 agcagctcca tggtgagcag gacggcgagc gtggtcttgc cggaacccgc ggctccgagg
     6721 agggcgagac ggcgcttcgg cagcgcgagg aacccggtga gcaggtccgt gagttggtcg
     6781 gcccggcctc gtacgtcccc gccggtgtgc gcggcgtggt cggcccggcg ccttcgggga
     6841 gcccagcgga ccgccatcgc cgcccggtcc ccgcccacgt cccaggcctt ggcctcctcc
     6901 cgccactgcc ggtagacggc ctcggcgagg gcgtgcgccg acttctccga cggtgtggcg
     6961 gacggcggcg cgtggacgtg gatctcgccg aagttgtcgc ggaactggat gacgatgtcg
     7021 gcggtgccct ggaagatgtt gttcacgtcg ccgcccggct ggccgtcggc catggctgcc
     7081 acctcgagtc aatgcggtgc ccggcgttgg cctgagggga gggggccggg cgaatgcggt
     7141 cactctacaa ctctcctgtt cggacgaagg gttgaatagg tcaacagctc gatagggcgg
     7201 aatggcctgt tcagggtcgt cctgtcgtcg tggccatggc gtacagccgc cgccagtcca
     7261 ggcggggctt ggcccggggc acgcccgggc gtcggcgcgg cacgcgtacg cgcagcgcgc
     7321 cgggttcgat cgcgcagcgt acgggggccg ggagggcgag ggcctccccg tcgacgccga
     7381 cgctcacttc gggcgtgtcg gcctcgatga ccgcctcgtg ggtggtgagg agcgtgaggc
     7441 ccggcgagtc gggggcgagg agcaggtcgg cggcctgcgc ggcggtgtcg accttgacgc
     7501 ccagcaggcc caggactccg ccgtcgagcc ggtcgcgccg tccgaggccc gcgctgtcgc
     7561 cgacgcggta ggggttgttg ctcacgagca cggcctgcgg ggcgtcgatc gtgtcgcccc
     7621 cggcgtggac gcgcaggtgt gggccggtgt gccgggacag ggcgtccggc agcagccgga
     7681 gaatggtacg gatcttgtcg tcgcggtagg cgcggctgcg gacgatggtc gcgtaggcgc
     7741 cgaacgaggc gttgttgacg aaggcgcggt cgccgacgcg gccgaggtcc acgcgcagtt
     7801 cgacgccgtc ggtgagggcg ttcaggcacg cgacggggtc gtcgcggtcg aggccgaggt
     7861 cgagggcgaa gtggttgcgg gttccggccg ggaggaccat gaacggcagg ccgtgcgccg
     7921 ccgcgacatc ggccacgagt gcctgggtgc cgtcgccgcc ggccacgccg aggaggtccg
     7981 cgccgtcggc ggcggcccgg cgggcgagag cggcgacgtc ctggccgccg tccgggtcga
     8041 gcagcacgac tcgtgcgccc agggcctccg ctttctcccg cagcccgaac tcctcgacct
     8101 ttccgccgcc cgatcgcggg ttcatgatga ggtacgggcg cgaaggcggt gcggcggggt
     8161 gttcccgggc cgtggtcgag ggactgccgg cgcccagcgc ggtccagccg gcggaggccg
     8221 cgccggccca cagcacgagg cacaacagga cgagccacag cagtccggcg gcggtgtaga
     8281 ggacgatcgc ggcgacgggg gcggcgacgg ccagcccggc ggccaggatc cttaccgggc
     8341 cgcgccgggc ggcggtccac cacaggccca tgacgaaggc gaggagcgcg gcggccccga
     8401 cgccgagcag caggaggctt ctcggtcccg cgatgacgag cagcaggatg cccgtgccgg
     8461 cggccgcgat cgccaggcgc gcgaagcggc gccgcctgat ggtctcgtgg gggtccggag
     8521 caccgtccat cgtctctccc gtccacgtcg gtgtcggtac cactgtcggt gtcgtccagg
     8581 gtgtggggcc ctgtcgccat tggacgacgt cggccctcgc cacgccaacc accacgggga
     8641 gcgggagccc gccgacgggg gcgtacggga gcggaatgcg ctacgcgagc agcagggcgc
     8701 ggtcccacgt gggctcggtg tccgtggccg ccgccagcag ggcgagggcc acaccggccg
     8761 ccccgtcgag gaagccgggg tcgtcggccc gtgggaagcg cgcggtcgcc agcccttcga
     8821 ctgccgtggt gagttcgggg tcgccggtgt cgtgggcgaa gcgcgcggtg atgtggagca
     8881 ggccggccag gccgtggcac aggccagggt cgacgtcgat acggcgtgcc gcggcggggc
     8941 gccggtggac ggccttgagc gcccgtaccg cgagctcgcg cggggccgtg tcgccgagtg
     9001 ccgtccccgc cagccagagg gcgcgggcga tgccggggct cccccggcac cacgaggcgc
     9061 gtacgggcgt gcccgtggcc gggccggtcc agttggggcc ccacggatcg tcggcgcgcc
     9121 gttcggtgag cagcgcggtg tacccggcga cggcttcgcg ctggccgggt acggtgacgc
     9181 cctcgccgag ggccagtgcc agcagggcga gcggtccgga cactccgtgg gcgacgccgc
     9241 agtcgggtgg gggccggcgg cttgcggcgg tggtgagggc ggtgaggacg tcgcgcaggg
     9301 cggccagtga ggcgggctcg tggtgccggc cgaggaggtg ggcgcccgct ccggtcagcc
     9361 cggagacgag gtcgagggcg cgctccggag ggtcgtcgcc gagctccttg gcccgtcggg
     9421 acgcttcggt gacgacgtgg gtgtgcgcgg tcggcaggtc gtgtccgagc acccgcgcgg
     9481 cgagggccag gccggccgcg cctccgaaga ggccggccga ggcgccggtc cgctcgtact
     9541 cccgtgccac cgcggccagg tagtcctcgg cgagcgtctt ccagccccgg ccgggcaggc
     9601 agcggtccag ctggtggtag gcgagggcca ggccggcggc gccggcggcg aggtggggtc
     9661 gtacgcggcg gggcacgcgg tgcgggcggg cggcggacag gacacgggcg agcgtggtgg
     9721 cggccgtggc cggggacagc agggggcgcc atggccgacc gggcgcgccg gtcatgtgcc
     9781 ctctcctctg cctggtcgtc cgggagttct gtgcggcctc cgccgccggt gggtggccgc
     9841 cgcacagaac ggtcgggcgg gcgtcagccc ttgcagcgcg gcccgatttc ggtgcactgg
     9901 ccgctcgtgt ggtcggtgtc gcagcacatc gcgggttcca gtgcctgctc gtcggtctcc
     9961 ggcagttcct ggagctccag gaccatgtcc tccatgggta tcacctcctc tcgggtcggt
    10021 ccggggcggg tgacgtgtgg tcggtccggt cggccgtcca gggccggccg ccgccgtgtt
    10081 tgaggcgcag caggaggtcc agggctccgg ccaggccgac gtggtagctc acgcagaagt
    10141 cgcggagggt gtcgtcgggg acgaccagcc ggccgtcgcg ccgggcggcc cgtgcgtgga
    10201 ggcagtaggc ggcctcggcg gcccgggtcc ggtaggtgtc gtcgccggtg gcgtcggcca
    10261 ggtcgaggag cagctgggcg ttgcccgcca cgccgtggca ggtgccggtg ccgagccgcc
    10321 agcggtcccg gtgggcggcg cgcgccgcca gttcggcgtg ctcgcggaag cgcggctcgc
    10381 cggtggcctg ccacagccgg atgagggtgg tgccgatgcc ggaggcgccg ttgcaccaga
    10441 agtcgaggcc catccgctcg gtgcggcccg gtcccttggg ccagacggcg atgtcgcccc
    10501 ggcgctcggc gagcgcgcac agcgcgtgtc cgccgccgat cgcgatgtcg gcgagttccg
    10561 ggcggtcgag ctcactgcct gcggcgagca ggaacgcggc gtggcccgcg acaccgtggc
    10621 cgaagccgta cgaaccggag cccgcgagtt cgcggcggtg cggcgggccg agcggccagt
    10681 ccactccccc gccggcccgg tcggcctcgg cggtgaggcg gatcacgctg tccgcgcagg
    10741 cggacgcccg ttcggcgaag cgctcgtcgc ccgtggtgcg ccacaggcgc agctgggcga
    10801 gcccggcgcc ggagaggccg tggcagacgt ccgggtcggc acggtccagg gggatgtcga
    10861 gggcgtactg ccgggcgcgg gccgcgaggc cggggtcgtc gagggtgcgt gccgcgtcgt
    10921 gcagcgccca gacggtgccg gagcggccga agtagagccc gggcagggtc cggccgggca
    10981 gggcgagtcg tgcgtcgatc cagtgggtgg ccgtgcggag caggggggcg agggcggggg
    11041 cctcacccgt gcggacggct ctgtcgagta cggcgaggac gcccgccgct ccttgctgga
    11101 ggttgcaggg gtcgccctcg ggcagggagg cgggcctggg ccacaggtgc tcggcggtcg
    11161 ggtcggggtc gacggtcgcg gcgatgtggg cgaggccgtc gccgagcagg cggtcgaggt
    11221 cggggccggt gagggcgggc gacggggtgg gcggcggggt ggccggttcg gctcgtagga
    11281 aggtggccgc cgcctccagt ggccggcggg ccggtgggtc ggcgatgagg ccgaggacga
    11341 gtggcgccag ggcgcggagg gcggggcagt ccggggcggc ggccgccacg agcgtcgcga
    11401 ggcgttcgcc gggcgggcgc gcgggcggtg tgtccggggc gaggacgggg ttgatgccgg
    11461 cggtggcgtg cagcagggtg acgcccaggc tgtagcagtc ggcttcgggg cccggtgcgg
    11521 gaccggcctc cgtccgggag aggtattcgg gcgcggtgaa gccctgcgtg cccagtacgg
    11581 gggccgtgtc cccggtgcgc acggcccctt ccaggtcgac gaggacgggc gtgccgtcgg
    11641 gccgcacgag gacgttggtc ggtttgaggt cgcggagtac gaatccggcc gcgtgcacca
    11701 cgccgatcag gcgggtgagg tcgcgcgcga gccgccgggc gtccgcgacc ggtagccggc
    11761 cgccatggcg cgaggccctg tcggccgacc actgctggag gttctcgccg tcgatcaggt
    11821 cctcggcgag gaagacgtgt cccccggcct cgaagacgcc gtgcggggcg ggcgcgacac
    11881 cgtgcggggc cagcagggac agcacctcgg cctcgtgccg cagccggtcc cgggcgtcgg
    11941 tcccgccggg ctgggctccg acgtgcggcc gggcctcctt caggaggacg tcccggccgg
    12001 tgtggcggtc ccgggcgcgg tagacgccgc cgcggttgga gtggcggatc gcctcgtgga
    12061 cgaggtagcg gtcggcgagg aggacggggc cgccccggga gcgggggcgt tcggggacgt
    12121 cgtcgaaggg cgggcgggcc caggcgggcg gggagaacca ggggttgcgt tcgtcggtga
    12181 cgtaggttcc gtcgggtgcc tggagccgcc cgcggtagaa accctcgtcg tcgagctcgc
    12241 gcggcgggga gaagcagccg tagcggtagt ggaccaggct gccggggcgg taccgccggt
    12301 ccgagaggat cacggggccg gcgagtccga gggtggctcg gtgcagctcc tcggcgaggg
    12361 tgcgcagctg ctcgtcgtcg gcggggtagg cggtgaggaa cttgccggag tgcggcctcg
    12421 gggcccgtac cgaggtgagg tcggcggtga cgcgcggcga taccgcgaac ttgaacgcgc
    12481 agccgtgcgc cacgaggacg cgagccgcgt gctccagcac ctggtgggcc gaggcgacgg
    12541 tcgccgacac atggagcttc cacccctgtc gccgagggcg gtaccccggt ggcgcgagcg
    12601 cgcaccacgt ctcgccgttc ctcatgctcc acgcggagcg ctcggccccg aggatccgcg
    12661 tggcgatcga ctggtagctc gcccgggggc ccaccgtcac gccgtcagaa tggcatgggc
    12721 cccggccccg ggcaacggtc cggtcggtgg gcgcggaggg ttccgcgggg ggcggtcatg
    12781 accggcgaag ccacccgtat cgcaccaatg gcatgatcgg actctcgacg agcgccccct
    12841 cgcccgtccc gcaccggaag gccacgctgt ccggcacgaa gagtgaccgc ttcaacaacg
    12901 tctaacaaat cggccaaaca attgatatct ataaaccaca gaattgattt cgccgcgtgg
    12961 cgtaggccac gggtgatcct gtgggccacg gcgggtgtgg tggcccttgg attcctcatc
    13021 gcgctggaga tcgtcgcccg tcgctacgcc ggcgtaccgg ggccgatcac caaccaggcg
    13081 aaagaggtga ttttcgcccc caagccgggg ccgctgtacg gcggtctggc gttgatgatg
    13141 gtggtgctca cctggcggca gcggttcatc gcggccggtg ccgcggtcgg catcgacgtc
    13201 gtcttcgtgc tggtgcggtg ggcggtcggc gccgacatgt ccgacggccg ttacttcggc
    13261 aacggcgcgt tgtgggtgat gctgggctgc gccgtcatcg ccgtcacgcg ccgcaccggc
    13321 cgggagcgcg tcctgctgct gcagggcgtc gggctgggcc tgctgctggt ggccggtcgc
    13381 aagaccggcg acacctggct gctcatcacc tcgaagaccc gcccgacggt gctcgaccag
    13441 tacgtggcga ccgccgatca cgcgctgggc aacccctcgt ggctggcggg ccggatcctc
    13501 aaggccaccg gcccggtcgg cattcacgtc ctcgacctgg tctatgccca gctcgcggtg
    13561 gcggcggtcg ccgtcgcgct gtaccagctg cgcaatgtgg cgacggagcg ccgctttccg
    13621 agccaccatc tggtgcgcac cttcctggtg atcggcctcc tcgggccggc catctacatg
    13681 atcttcccgg tggtcgggcc gatcttcgcc tacggtccgg gcacctccgg caccggcggc
    13741 ctgcaatggg cggtggccga cctgtggccg cacacgccgc cggcgatcgg cgtcccgcac
    13801 ccggtgccgt acgacgggat caccccgcgc aactgcatgc ccagcctcca cacggcgtgg
    13861 gccaccgcga tcttcatcca ttcccgcaag ggaccgcgcg ccctgcggta cgcgggaacg
    13921 ttctggctgg tcgccacgct cagcgcgacc ctgggattcg gctaccacta cggcgcggac
    13981 ctgatcgccg gtgtggtgtt ctcgctgacg atcgaggcgg gcctgcgctc gctcgaccgc
    14041 ggctgggacc ggtcgggaac ccggctggtc gcctacggcg cgacggtctt caccgtgctc
    14101 ctgctgtcct atcgctatct gccggtggag atggccgggc atccgtggct gtccggaccg
    14161 cttctcgtcc tggcgatggg ctcggtgatc tacggctacg tacggaccac caggtcgtgg
    14221 gagccgaagg ccgcgccggc gcggcgaccg gaaccgcaac tcgaactcgt gtgagtcatc
    14281 gacgacggga gccaccggcc tggccaggcc ggtggctccc gtcgttcggg cagatcacgt
    14341 tcgggtgggt cactgatggg gggacgactc cccgcggtgg ccccagccga ggacgtcctc
    14401 ctcgggcgcg ggcttgtaac caccctccgt cgtcttctcc gcttccttcg cttttaccgc
    14461 cgccctttcc ttcttctcct gcttttcccg ctgctttcgc tcgtgttcgg ctgcgcggga
    14521 ttccttgttt ccccatttcg gcagtccgac catggcgggc cccctctcgc atcggacttc
    14581 cgcgacaatt tcaggttcac acgggggcgc ggggcacgca tccggccacc gcggcgccgt
    14641 cggcgagtgg accggcgagg tctcgcggag gagcctggag tcatggggtc gctctcgcgc
    14701 tcggatcccc ggccggggcc gggcgtccac gggggcctct tccggctggg gcagtgcgtc
    14761 ccgttcgcga tcgccctgct ggtgctgggc atcgagttct cgcccgcgca ctttctgtac
    14821 accggccctc tgctcacagc gacaccggcg ctggcggcgg tgacgatggg acctcggggc
    14881 accgtcgcgg cggcggccgt cgcgatggcc gtcagcgcga ccaccgcgac ctacaaccac
    14941 gcctggggca gcctccaggt cctcaccaac ttcctggccc tcttcctggt gtccggggcg
    15001 ggcttcctga cgagccgcgc cgtgcggacc cgccggcgga acgagatcga ccaggtgcgc
    15061 cggatcgcca cggcggcgca gcaggtcatc ctgcgccccg tgcccgcccg gctgggcccg
    15121 gtcggggccg ccggcatgta tctcgcggcg gaggcggggg cgcagatcgg cggcgacctg
    15181 tacgagatca cggagacccg gtacggggtc cgggtgatca tcggggacgt caggggcaag
    15241 ggtctgcccg cggtgcgctc ggcggcggcc gtactgggcg ccttccggga ggcctcgcac
    15301 tacgaggagg atctggtgga ggtgatgaac cactgcacgg ccgcgctgcg gcgggagtcc
    15361 gccgtaccgg gcgcgtacag cgaggacacc ctgctggagg ggttcgtcac ggcgctcgtg
    15421 gcccaggtgt cggaggggcc ggcggaggag ccggtggtcg aggtggtcaa ccggggacat
    15481 ccgccgccgc tggtgctgtc ccggggcgag gtgcgggccc tgaccccttc ctcgcctttg
    15541 ccaccgctgt ggctggagga cttcatgacc ggtcccccgg ccgcggcgga gagccatccg
    15601 ttcgcggtcg gtgaccgtct cctgctgtac accgacggcg tgatcgaggc ccgcgacggg
    15661 gacgaccgct tcttccccct ggccgaggcc atggaaaggg tggcggaagg aaccactcct
    15721 gccgacgccc cgcgggactt cctcgaacag ctccaccgga ggctcgtcct gcacacccgt
    15781 ggtcgcttgg cggacgacgc ggcgatgctc ctcgtcgacc ggctggagag atgaacccct
    15841 ctctcagggt gtcaggagct gtccgcgaag cgtcgacacc agctcgtcgt cgacgccgag
    15901 ccgctgcgcg gcgtagcccc gcaccgaccc gtaccgcgcg gcgagttcgg ccatgaagag
    15961 gctcatgatc ccggctgggg cgcggccgta ggcgggccaa ccgagcgtca gatgtggggg
    16021 gtagcgggct ggttcgacgt cggggcccaa ggcggcctgg tcgtacggcc ggtgctcgat
    16081 gctcaggttg tggtaggcga gcgaggggtg gtgcgggagg cgtccgctgc gttcgacctc
    16141 ccaggggtgt ctgaggtcga tcacagtgcg gacgcccagc gcgaggaagc ggtcccagtc
    16201 ccgggcgcgc gggcgtcgag gccggttccg cgtcgcgtct gggatcctgg gagtacaggc
    16261 ggtgtgctgg ggacgggtcg tgggcgggtg cgccacggcc gggaggagcg gactgtgacc
    16321 gatcgtaaac cccgtgtgtc ggacttcgag tcgtgggcgg acaagcagat ccgggaagcc
    16381 gaggagcgcg gcgacttccg cgacctgccg ggcttcggcc gcccgctggc gggcatcgac
    16441 cggccctatg acgcggactg gtgggtcaag gacaagatgc gccgcgagaa cctctcgttc
    16501 ctgccgccga cgctggcgtt gcgcaaggag gcggaggacg ccctggcggc ggcggtggcg
    16561 gcccggagcg aggaggaggc gcgcaggatc gtccacgaga tcaacgacaa gatcgccgcg
    16621 tctctccgca ggccgccgcc cgggccgccg ctcggtctgg tcccgttcgt catcgacgac
    16681 gtcctggccg cgcggcgcga gaagcgcggc gacggccgac catgacgtac cgctcccggt
    16741 cggactcgac ctggtggaca ggggcgacac ccgcacacca ctaagatcgt tcacttgtcc
    16801 gaccaggagg aaacattgcg caagatcatc acgggtgtgg ctctcgccct gaccgcggct
    16861 cttctgacgg gatgcggcag cggcgacagc agcccggcgg ccgccgacaa gcccgcgacg
    16921 tccgcgcagc cgaaggcgaa ggcggaaggc gggagcggcg aggtcaagca cgaggtgacg
    16981 ctggaagtcc tcggcagcga aacgacgtcg gtctactaca acctggacac caacaagatg
    17041 gaacaggtgc agttgccctg gaagaagacc tccaccatca ccttgacgac ggacgccgag
    17101 aagaaggtgg gcctgctggt gtcggtcgtc cccggctccg ttcacggccc tgacggcatg
    17161 ctgcacgcgg cgccctgcgt catcaccgtc gacgggaaga aggtcgcgga caaccaggac
    17221 ggcaagtccg acaagatgtg cgagtacaag gtgaagtgac ggttccggtc tccctccgcc
    17281 tcgggaggct tccggtgccg cgaggctggg aacggtcttt gcgaccagga agccggtgcg
    17341 cgataccgcg ccgggtgtgg cggaaggggc tgcgatggcg gaggaatcgg ctcgggagcc
    17401 gctgatcgtc tcggacgagg tgcgggaggc gctggacctc ggccggccgg tggtggccct
    17461 ggagtcgacg atcatcgcgc acgggctgcc ccggccgcgg aacctgcggg tggcggagga
    17521 gctggaggaa ctcgtacggg ccggtggtgc cgtacccgcg accgtcgcgg tgctggacgg
    17581 ccggccgcac gtcggcctgg acaaggcgcg actggcgcgg gtggcgggcg aggacgggct
    17641 gcgcaagctg gggagccgcg atctggcgcc ggcggtggcg gcgggggcga gcggggcgac
    17701 gacggtgtcg gggacggcgt tcctcgcgga acgggccggg atccgcgtgt tcgcgacggg
    17761 cggcctgggc ggcgtccacc gcgagtgggc acagacgcag gacgagtccg ccgatctgcg
    17821 cctgctggcg cggacccgga tcgcggtggt gtgcgcgggg gtgaagtcgg tcctggacgt
    17881 ccccgcgaca ttgcagcgcc tggagacgct gggcgtgggg gtactgggtt tccggacgcg
    17941 ggaattcccc ggcttctacc tcaccggctc cggcgtgccg gtcgactgga cggtcgggac
    18001 ggcggcggag gtggcggacg tgctgcgcgc ccaggacgcg ctgggtggcc cgccctcggc
    18061 tctcgtcgtc gcgaaccccg tccccgtgga tcagcagctg gacccggcgc tgcacgaccg
    18121 ggtgctggcc ggggcgctgg cggcgtgcgc gcgggagggc gtcaccgggc aggcggtcac
    18181 accgttcctc ctcgaccatc tcttccggca caccgacggc gcgtccttgg aggccaacgt
    18241 ggcggcggtg cgcggcaacg tccggctggc ggccgagatc gccaaggcgt acgccgcgtg
    18301 acgggcggtg ggccgggcgg tgggtcggaa ggcgggtcga gagggctgct cgtcgtcggc
    18361 gacgtggtga ccgacatcgt cgcccgccac cgctccccgc tcgcgcccgc gaccgacacg
    18421 gcggcccgca tcgcctccct gcccggcggc gccggggcca acgtggcctg ctgggcggcc
    18481 cgttcgggcg ccgaggacgt ccgtatcctg gcccgggtgg gcgcggacgc ggtggacgcg
    18541 cacgagcgcg tgctccgcgc ggccggtgtc cggccgcgtc tggtggccga tcccgccgcg
    18601 ccgaccggca cggtcatctg tctggtcggc gccgacggcg agcggacgtt cctcaccgac
    18661 agcggcgcgg tgctgcgcct gtccaccgcc gactgggacg gcgagctgct cgccggggtc
    18721 ggtcatctgc atgtgtccgg ctatctcttc ttcgccgacg ccagccgcgc ggcggcccgg
    18781 ctggcgatgg aggcggcccg cgcccgttcc ataccggtga gcgtcgaccc ggcgtcggcg
    18841 ggtttcatcg ccggcttcgg tacggaccgt ttcctggcgg cgctcgccgg agtggacgtc
    18901 ctcctgccca gtcaccacga ggcggcgctg ctgacggggc gttccgagcc ggccgaggcg
    18961 gcggccgagc tgagccggcg ctttccgctc gtggtgtcga cgaggggcgc gcggggcgcg
    19021 ctggtggcag cgtcgggcgc gatcgtcgcc cgggtgccgg cccgccccgc gacggccgtg
    19081 gacacaacag gtgcgggtga cgccttcacc ggcggtttcc tcgcggcccg tctcgcgggc
    19141 cacggcccgg tcgaggccgc gcggcacggc tgccggaccg ccgccgaggc cgtcaccgtc
    19201 atcggcggcc ggccgcgcga cccgggatga cggccttcac gacgtccggt gacggaggcg
    19261 gcgaattcgc tggcacggcg ggttgtccct gtgacagggt gcgctgccgt gagagacatc
    19321 gacagcatca cgatcacgac actcgccgag cgcccggcgc tgattcccag gatctacgag
    19381 atcgacgaca cctggccgta cttcaccgcc cacgagccgg tggtgggtgc cctgttgggc
    19441 cgggtgcccg aggactttcc cgactactgc gtcgtggcga cggacgcgac ggacggcgac
    19501 cgtgtcgtgg cgcgcgggct gagcgtgccc ttcaacgcct cgctcgacgg gcgcgaggag
    19561 acgccggacc aggggtggga ccgggtcctg gtgtgggcgt ccgacgaccg gctacgcggc
    19621 gtagccccca cgacggcgag cgcgctggag ataaccgtgg acagggaaca cctcggccgc
    19681 ggcctgtcct cccgcatgct caccgcgatg cgggaggccg tcggccggca gggccacgac
    19741 gtgctcctgg ctcccgtgcg gcccacggcc aagcacctgg agccgcgcgt ccccatggcc
    19801 gactacgcgc tccggcggcg cgacgacggc ctgccggccg acccgtggct gcgggtgcac
    19861 gtcagggccg gtggtgtcat cgagaaggtc gctccggcgt cgatgacggt cagcggctcc
    19921 ctggccgagt ggcggcggtg gaccgggctg cccttcgacc gcgacggcga cgtcgaggtg
    19981 ccgggcgcgc tcaccccggt gcgctgcgac gtcgcgcacg accgggcggt ctacgtcgag
    20041 cccaacgtct gggtccggca ccgcgccggc ggccggccgg ggtgatcgaa tgaccggacg
    20101 ccgttcttta ctgtggtgga gggaatgggc tcgcggcctg cccctgtgac gtgtccggtg
    20161 tcgtctcccg ctcgttcttg tcgtggaggc tcttccgtcg acgatcgaag gagtcatgat
    20221 gcgacgagtc cttgcgacgg ccgccctggc catggccgcc ctgggcgcgg gtgccgtcgg
    20281 gccgggggcc accgcgtacg ccgccccgct gcccagcggg ctcgacctga agggcgtcac
    20341 catggatccc ggtaatctgg ggtcggcggt ggacgaggcc gcccagaagt cgacgagggt
    20401 gatcggcgac gccgggggcg gtgccgtcgg caaggtggtc cccgcggccg gccggacggg
    20461 cgggacggcc gtgaagtcgt cgacgtccgc cgtccagcag accatcggcc gcgcggcggg
    20521 gtcggcgggt gagactgtcg gcgagaccgc gaaggcggcc accaaggacg gtccgccctt
    20581 cgggaggctg gcgcccggaa ggttggggca cctgccttcc tgacgccccc tccctggcag
    20641 gggtgcccgc caccggccgg tccgcgcccg gggcgctccg gaccggccgg atggggttac
    20701 ggaaggtcgt ccaggtcgtc gaggccgtcc cggtcgtcgc tcaggttgtc gttgaggtcg
    20761 tcgttgagcc gccggcgccg ctcgtcctgc tgcccgccct gcatgctctg ccgggactgc
    20821 tcgcgctgcc ccagcgtctc ctccgtcatg tcctcgacgt agtcgccgtc gtcgcggtac
    20881 gggtcgcgtt ccctgctgct gtccatgccg tgctcactcc tcgacgagac gggcggtggg
    20941 cggcttcgcc cccagcagcc tcacacgcac ccgctcgacg tgcatgtcgg ccgccggtgc
    21001 gcgggtcagg tcgtggggcc ctgcatgtgt tcgctgaccc actgaataag acccccggcc
    21061 tccatgttgg ggacgtacga ggccgcgttg tgctcgccgc cgacgttgat ccggtacttc
    21121 gtcttgatcg ggcccttgtt gttgccgtac ttggcgagga agcggtcgat gggcggcttg
    21181 accggttcgt tggagccgac ctggaaggcg aggtagacct cggggccctt cttggcgatg
    21241 aggcgctggg cgaggacgtc ggagttgttg tcggccttct ccttctcgtg gccggcccac
    21301 aggcgggagt cgggcacgat gtcggggccg gaggcgatga ccgccttgaa ctggtcgggc
    21361 ttctggagga ccgacttcag gcccgcggag gcaccggtgg aagagcccat gaaggcccag
    21421 ccgtcacgcg acttgatggt gcggaagttc tccttgacga gctggggaac gtcctcggtg
    21481 agccaggtgc ccatcttggg ctggccgggg atgtcgctgc cgtcccagta gagcccggcc
    21541 ttggggtcct tggggtcctt gtcgtggttc tcggggttga ggaccggcat ggcgatgatg
    21601 aaggggaggc tcttgccttc ctgggcccac ttggagatgg acgcctcgag cttgaggtcg
    21661 gtgcccatcc agtagttgtt ggggtacccg gcgccgccgg ggagggcgat gaggacgggg
    21721 aagccgctct tggcgtactt cgggtcgtcg tactccttgg gggcccagac ccagaccttg
    21781 ccttcgaagc cggacttctt gcccttgtag gtggtgacgg cgatcttggt gccgtcctcg
    21841 gggacggtgc cggagatctt gaagccggcc ttggggccga ggggcatctg ggccttggag
    21901 ccgggtgcct ggtcgccgtt cttgccgtcg cccgacccgc cgaaggagat cgcgtcgccc
    21961 ttgtccgtga acgggggtat ctcgtagtag gacatcaccg gccaggcgat gagaccgagc
    22021 gtgacgacgg acgccccagc gatcacccag cgtttggcgc gggagggacg gcgccgggcc
    22081 tggtaggtcg tgggcgactg gtacgacatc ggaaatcctt actgcggtga cgacaagggc
    22141 gcggatactg ctggatagct gtgacatccg taaggagtgg gcccgtccgg cagcgggttc
    22201 cggctgtcac agaatgatga tgtttccccg ggcctgacgc gtggcgcggc cgtcacgggg
    22261 agtgcgggaa cgggaccgcg agcggaaccg gcccctgctt cgagggtaga cggccggctg
    22321 tgccctcaga tgccgaaggg cgccgcgtag cggaccgtgc ctgccggcag cgggtgggcg
    22381 tcgtccaggg cgagggccat cagcgcctcg tcggggacgt cgatggtcac gccgatgcca
    22441 tgggccgagg cgcgcccgaa gccgaagcgc gggtagtacg ccgggtgccc gaggacgacg
    22501 acgtagcgct cgcccatctc cccggccgcc cgcagcgcgg cgcggacggc tgccgatccg
    22561 gcgccgctcc tctgcagccc gggccgcacg gcgacggggg ccaggcacag ggcgggggtg
    22621 tcgccgatgt ggcagcgcgt cagcagcgcg tgaccgacgg gttcgccacc ctcgtcggtg
    22681 acgacgaggg acaggccgtc
//
