LOCUS       NZ_CP029617            37105 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8145974
            Orig. end                         :: 8183079
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..37105
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /product="azole-containing-RiPP"
                     /region_number="35"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..37105
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22792
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22792
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12792](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12792)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    343..358
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(902..922)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.07"
                     /tool="antismash"
     misc_feature    complement(1193..1204)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.62"
                     /tool="antismash"
     gene            1644..2315
                     /locus_tag="DMA15_RS35870"
                     /old_locus_tag="DMA15_35855"
     CDS             1644..2315
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014906.4"
                     /locus_tag="DMA15_RS35870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35855"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_164551906.1"
                     /transl_table=11
                     /translation="MKQRPARQPLSREQIVQAAVRLLDEGGVRNLRMRQLADSLNSAPM
                     SLYWHVSTKDDLLELAVDAVFPDPPSRSGTGDWRDDIKAGATDLFEVLLRHSWMIELMG
                     GHPPVGPRALAHTSAIIEILEQAHFSPRQLDSALSAIYYYTVGAALSEASWQAMARQSA
                     ESEEEWVSRLGPYLGMATQSHPASLGDYVKRSASSSTGQRFHDGLECMVSGMGQMRSED
                     S"
     misc_feature    complement(1678..1693)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            complement(2819..4051)
                     /locus_tag="DMA15_RS35880"
                     /old_locus_tag="DMA15_35865"
     CDS             complement(2819..4051)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_transf_28"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1102: glycosyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018434.4"
                     /locus_tag="DMA15_RS35880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35865"
                     /product="glycosyltransferase"
                     /protein_id="WP_164551907.1"
                     /sec_met_domain="Glyco_transf_28 (E-value: 1e-07, bitscore:
                     30.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILLVTWGSTGDVLPYAGLGARLKAAGHEVTAATSERHAARFQA
                     GGMPVHILPLARHEESALSAERFDRWQSPARLRRRKRNAQEMTQVIARGVLEAVTNGAE
                     IILAHPMTHPLCAVIAEGTGRTCIGIYAASPGMLVPQAGANTATGRGYRAAERLVWAAT
                     HPLYAPALSWLQRELGARSRRFRTPSGILRGARVLHGFSPALLPKRLVLPQGHKCAGYW
                     WPTTDSTWRPDDRLADFLASGPAPVFFGFGSLSIGGAEPLSDMIKSVVRRLGVRAVVQA
                     GWQGLDVHGDGILTIGECPHDWLFPRMSALVHHAGSGTVGAGLRAGVPAVPVPLVLDQP
                     FWARRLTALGLSPGYVSARRLTADSLSATLRTALQDKRYRERCAKISRTIESEDGTIAV
                     LDELEGHLASR"
     gene            4205..5104
                     /locus_tag="DMA15_RS35885"
                     /old_locus_tag="DMA15_35870"
     CDS             4205..5104
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (57-267). E-value:
                     1.2e-19. Score: 62.8. Matches aSDomain:
                     nrpspksdomains_DMA15_RS35885_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="DMA15_RS35885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35870"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_125516961.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-09, bitscore:
                     37.3, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 2.5e-10, bitscore: 39.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLSTDTAVTVADTTLDYRGFRYLARTSTAGSSATEPLVVLGGSS
                     QDRFSWMRYERWLLPHTTVVTLELPGYGGADALPVEHGMDFLADAVCHATEALALGRVN
                     VFGACFGASIALRLAQRHPDHVARLMLGGTAVEISPEYTASARRWRRMVDDGQFDEMAQ
                     DMVEQFMAPPGHGKVRRQAAVARLMRQRFACLTARELAMDITHHERLLTHPWSLPGLPV
                     SAPVLVFTGEHDTITPPEVGRRVAADLGARFTTITESDHLVQIERDSDLADLMAHFFTD
                     RALDQLPYLNPVEHFTRT"
     aSDomain        4376..5005
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS35885_Abhydrolase_1.1"
                     /evalue="1.20E-19"
                     /label="DMA15_RS35885_Abhydrolase_1.1"
                     /locus_tag="DMA15_RS35885"
                     /protein_end="267"
                     /protein_start="57"
                     /score="62.8"
                     /tool="antismash"
                     /translation="LLPHTTVVTLELPGYGGADALPVEHGMDFLADAVCHATEALALGR
                     VNVFGACFGASIALRLAQRHPDHVARLMLGGTAVEISPEYTASARRWRRMVDDGQFDEM
                     AQDMVEQFMAPPGHGKVRRQAAVARLMRQRFACLTARELAMDITHHERLLTHPWSLPGL
                     PVSAPVLVFTGEHDTITPPEVGRRVAADLGARFTTITESDHLVQIER"
     gene            complement(5269..5691)
                     /locus_tag="DMA15_RS35890"
                     /old_locus_tag="DMA15_35875"
     CDS             complement(5269..5691)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015928.4"
                     /locus_tag="DMA15_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35875"
                     /product="peptidase inhibitor family I36 protein"
                     /protein_id="WP_125516963.1"
                     /transl_table=11
                     /translation="MRKRIAACVAATTAVLALAVPTAASAEETRVTAVAGVEGLYRLSG
                     GDYVARAWSECGSGSCFFQNDGGGGWLWVVPSCGHHKVPSWFEDRASSAWNRTPTRIHI
                     YKHSNYSGYLGTVPGWFKGDLARADEDVMSSVFADC"
     gene            complement(5725..6810)
                     /locus_tag="DMA15_RS35895"
                     /old_locus_tag="DMA15_35880"
     CDS             complement(5725..6810)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020610447.1"
                     /locus_tag="DMA15_RS35895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35880"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_125516965.1"
                     /transl_table=11
                     /translation="MSSINEAARQTDGGDGPVVSASTDGVPAPERFDWWAQMVGAEVMP
                     VAIHSAHAPRFRGSVEAVGMPHSQVAAFAFSPMVARRSPVHIRRHDPEEYYLVLVRGSP
                     IRLEQARGVACLGSGDMSLFTTSAPLVCDFLDRGRQTRLTLLRLPRTVLPLAGGRADRL
                     LAEPLSTRAGSGSAALLGSYLAGLPTAAHTCGPAELARLGAIGIDLAATVLAGRLGAQE
                     ALPAETRRAAVRSRIKIFIEQNLGDPELLPAAIAAHHHLSVRSLHLLFRNEPETVGAMI
                     RRLRLERCRTELADPALGTRTIAATAARWGFRHPADFSRAFRRAYGFPPSEVRARTGAR
                     ALDVQQVCARCRRSAGRHGSQ"
     gene            complement(6933..7394)
                     /locus_tag="DMA15_RS35900"
                     /old_locus_tag="DMA15_35885"
     CDS             complement(6933..7394)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS35900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_35885"
                     /product="hypothetical protein"
                     /protein_id="WP_125516967.1"
                     /transl_table=11
                     /translation="MSESTKNGTSPVGDTSTGDKADRSKAESAKATTAKAAGGTARSAS
                     KTASGAAAKTGSAARDVKSSVAEAGKGAASVGATLGEKAKAGGELLSAVPQKTMQAAAT
                     TWTVLKNRKAIAVGVGSGAVAMLAGAYALGGANVRRGQGPLTRATRGVL"
     gene            <7592..>7774
                     /locus_tag="DMA15_RS35905"
                     /old_locus_tag="DMA15_35890"
                     /pseudo=""
     CDS             7592..>7774
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964443.1"
                     /locus_tag="DMA15_RS35905"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DMA15_35890"
                     /product="TauD/TfdA family dioxygenase"
                     /pseudo=""
                     /sec_met_domain="TauD (E-value: 7.2e-09, bitscore: 34.5,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGGPIPGAVMDHLRACYRAAAPRFDYRADDVLVIDNMLLSHGR
                     EPFTGPRRIALAMAEP"
     gene            7815..9143
                     /locus_tag="DMA15_RS35910"
                     /old_locus_tag="DMA15_35895"
     CDS             7815..9143
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720433.1"
                     /locus_tag="DMA15_RS35910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35895"
                     /product="MFS transporter"
                     /protein_id="WP_125516969.1"
                     /transl_table=11
                     /translation="MFARSLRSNRDFSVFWAVQALSEVGNAFSLVALPLLVLHTTGSAA
                     QMGLLTAVAGATALLTGLVGGTWADRFDRRLLLMLCDAARLVLYGAIPVCWALNPQIWL
                     LYVVMALASVFETLFRITYVTAVPNLVDKEQIVAANGRLEATNAIAYIAGPALAGVVAG
                     LFGPTAAVAINAGSFGISLVGLAFIRLRPTVRSSADEAENKAAWAQDLRSGFLVGAAFL
                     WRTPVLRALTLLLTVTTFLSLGMTDVFIYHLRHGLGQDERTVGYVLALAGLGTCVAAAA
                     TAWLRRSWGFGTCWLGAMGLCSVSVLVLGGTGQVAVATVTICLYSFGMALAGICSMSLR
                     QQVTPDHLLGRVTSAFWTIHGSLAPLGAALLTALVGRLGTRGPLTAVAVVFLAVVVAAA
                     FTPIRQRRPELTAVPLPRTRPTPPPPRDTPPSAACGEGDVHHI"
     misc_feature    9367..9381
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    complement(9612..9626)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            9617..9763
                     /locus_tag="DMA15_RS36920"
     CDS             9617..9763
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS36920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164551908.1"
                     /transl_table=11
                     /translation="MTMTTRCSVSVRWQHVRVVIIVMVLVFLSVMTHGDGDMTLVDALL
                     PRV"
     gene            complement(10001..10894)
                     /locus_tag="DMA15_RS35915"
                     /old_locus_tag="DMA15_35900"
     CDS             complement(10001..10894)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="DMA15_RS35915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35900"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_125516971.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.3e-09,
                     bitscore: 34.7, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-07, bitscore: 30.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.1e-18, bitscore: 66.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLSVSEYVRESTSPHGGSVLLDVRSGHCFAMNSMAHALWREWH
                     RSGNFDSAVVVVAGRYPDVQHDRIRKDARRLADDLISRGLLAAHAPSLTPPAAGQHAYP
                     HPAADAPSPPAERAPATAGRRPDGRGSAGHAPSVGEVPPVTEVPLAAAQMTMSAEPVRD
                     GGDRSLRGAVTAVLSLVVLLGALLLIRLPLRTVSRTVGWTARTWCRREATPEQASAALA
                     AVRRAARWYPGRAACLELSLATLGSLALTGRRVVWCIGTADDPYRFHAWVEAQGVAIAS
                     PDEYGNSEFRRVLCVS"
     aSDomain        complement(10634..10849)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DMA15_RS35915_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.10E-11"
                     /identifier="RREFam002.1"
                     /label="DMA15_RS35915"
                     /locus_tag="DMA15_RS35915"
                     /protein_end="87"
                     /protein_start="15"
                     /score="34.7"
                     /tool="antismash"
                     /translation="PHGGSVLLDVRSGHCFAMNSMAHALWREWHRSGNFDSAVVVVAGR
                     YPDVQHDRIRKDARRLADDLISRGLLA"
     gene            complement(10891..12792)
                     /locus_tag="DMA15_RS35920"
                     /old_locus_tag="DMA15_35905"
     CDS             complement(10891..12792)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="DMA15_RS35920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35905"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_125516973.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.5e-24, bitscore:
                     84.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPAASAAATDPRCPSPALPPTNGPTIAGLLSAAPAPAPHGATR
                     LWPGEPLLWSWGPWHPGEVRTVQCAHARLAAIGQCLADEATMRHDLRRAVQDGRWERLT
                     HWPGAYLLLVLQDDGHLTAYADPAGQFPLYYGRHGQNTVLSTRARTAAALSGAAARPDA
                     AALAAHIVCPAVPELTEGRTAYDGIRRLGGGQALRVTPSGDCTPWTYEDLAPDPGTRFE
                     DSAAQLRSALTRAVILRTDTAPRITSDFSGGLDSTSLAFLAARTTGRPPLDAFVYHHPD
                     APAGDLAHALAHAEHAPSVRLAVTRGSEDSLPYSGLPEHGSADQPDPAAVIGARQQLRL
                     DHIARGGPGIHLTGEGGDALLAAPPSYLGDIAATAGLRRLLSDGRALARIRQLSPADVI
                     LRARCLARTPLHQAMSGLASHLDDPLDHPPQWADAVAWWPAPGPETVWLTTRARRHLAE
                     LAEERARSTDLVSPSGPATPGTRAVLCELRTSAAVQAQFTSTARASGIWPHAPFLDSEV
                     VRACTRLPLPHRIDPFAAKPLLAAALTGLVPDPVLRRRTKGDYAAENYHGVRRSATQIR
                     ARLLRSPLADLGIIEPLRVIASVERAVAGLAAPFPALNRLLGADLWLTAGASGQERS"
     misc_feature    complement(12109..12111)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12810..13013)
                     /locus_tag="DMA15_RS35925"
                     /old_locus_tag="DMA15_35910"
     CDS             complement(12810..13013)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS35925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_35910"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_125516975.1"
                     /transl_table=11
                     /translation="MTYEPIAVSPYEDFGYPRQAVKAEAVPSREEPAAYEPPMVVDLGH
                     VREVALGSSPSGSADANAQYYY"
     misc_feature    complement(12974..12991)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.41"
                     /tool="antismash"
     gene            complement(13408..14517)
                     /locus_tag="DMA15_RS35930"
                     /old_locus_tag="DMA15_35915"
     CDS             complement(13408..14517)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012692.4"
                     /locus_tag="DMA15_RS35930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35915"
                     /product="ROK family protein"
                     /protein_id="WP_206302899.1"
                     /transl_table=11
                     /translation="MAIKSGTQADIAHRTLLSQATVSAAVQELAKVSLVPTTKQRGKVC
                     LSAVNDVGVGVHLGFNHMTVVARRLDKEFDRATSRVSSEGVSRGWSRALPEVKQMIDEA
                     IEGTERHRSDVFSLGVAVPRMINPRTGGFTPPILPPWRAGDDPAKDLGTWLGVRAFIDN
                     DANLGALAEQTYGTREHAETVVYVKASTGIGAGIIVHNSVLRGHGGMAGELGHLTVDPH
                     GAVCQCGGRGCLETVIGADALIAQVRAARARNSLPAPETLEQVITAAQAQDAVCMRVIH
                     DAGRCLGQSLAQLCNLLNPDLVVIGGQLAQSPLLLEGCKESLRRFALPGAVAEDSEFVL
                     DLSELDTRAEAQGALILGLRGMEHAANNT"
     cand_cluster    13710..37105
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    13710..37105
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[23709:27105](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(23710..27105)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="2"
     misc_feature    14630..14639
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.04"
                     /tool="antismash"
     misc_feature    14632..14645
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.05"
                     /tool="antismash"
     misc_feature    14633..14646
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.16"
                     /tool="antismash"
     misc_feature    complement(14649..14658)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.85"
                     /tool="antismash"
     misc_feature    complement(14775..14789)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.68"
                     /tool="antismash"
     misc_feature    complement(14780..14798)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.31"
                     /tool="antismash"
     misc_feature    complement(14785..14799)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.56"
                     /tool="antismash"
     misc_feature    14786..14799
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.74"
                     /tool="antismash"
     misc_feature    complement(14787..14800)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.87"
                     /tool="antismash"
     gene            14981..16384
                     /locus_tag="DMA15_RS35935"
                     /old_locus_tag="DMA15_35920"
     CDS             14981..16384
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839230.1"
                     /locus_tag="DMA15_RS35935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35920"
                     /product="M28 family metallopeptidase"
                     /protein_id="WP_125516979.1"
                     /transl_table=11
                     /translation="MSQQTGSSRRTVLTAAAAATTAGAVGLQTGPATARDGGRPTAQEP
                     PRELRALLREIDHRRIEATVRRLAAFGTRHTLSSQDDPVRGIGAARDWILAELRRHARR
                     SGGRMTVELQSYVQEPGPRIPTPTRITNVVATLRGSASPDRLYVVSGHYDSRASDVMDF
                     TSDAPGADDDASGVALVMELARVMAPRRIGATLVFAAVAGEEQGLFGAAHMAERFKQRK
                     ADVQGMFTNDIVGSSTADDGTRDPRTIRLFAEGVPSSETPEEAAVRRAVGGENDSPARQ
                     LARFVEDVAANDATGMRVRVVHRRDRYLRGGDHIPFLERAYPAARFTEPAEDFAHQHQD
                     VRVVDGKQYGDLPEFCDFPFLARVARVNAATLWSLAQAPGTPRGAKILTAALTNETELV
                     WERGTEADLTGYEVVWRETTDTDWTHVIDVGDATRHTVDLSKDNVFFGVRAVGRSGLRS
                     PVAFPAPQR"
     gene            complement(16282..17217)
                     /locus_tag="DMA15_RS35940"
                     /old_locus_tag="DMA15_35925"
     CDS             complement(16282..17217)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525992.1"
                     /locus_tag="DMA15_RS35940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35925"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_125516981.1"
                     /transl_table=11
                     /translation="MDFRTELSAFLRSRRARLGPEDLGVRPFGGRRRVPGLRREELADL
                     AGVSVDYYIRLEQGRTHNVSDSVLDAVARALRLDEAERAHLGHLIRALRHPASTPPVPQ
                     PVRPGVRVLLTALGEVPAYVLGRRLDILASNAAARALFTDFEALPAGQRNAAWLVFLDP
                     AVRGLYPDREAWEESARGTVAALRMDLGRYSCDDRLCDLLGELSVRSEDFRALWAEHHV
                     GEHAYGIERLRHPTAGELTLRRETLRLPDEGDQCLVTYAAEEGTPSSSALAGLGAPQRC
                     GAGNATGLRRPERPTARTPKKTLSLDRSTV"
     misc_feature    complement(17291..17304)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            17432..18223
                     /locus_tag="DMA15_RS35945"
                     /old_locus_tag="DMA15_35930"
     CDS             17432..18223
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (20-190). E-value: 3.5e-14.
                     Score: 45.1. Matches aSDomain:
                     nrpspksdomains_DMA15_RS35945_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640883.1"
                     /locus_tag="DMA15_RS35945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35930"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_125516983.1"
                     /sec_met_domain="adh_short (E-value: 4.9e-35, bitscore:
                     119.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITTEQTTSLTRPLTGRIAVVTGASSGIGEATAHKLAARGAHVA
                     LLARRADRLDEHVARIEAAGGTALALPTDVTDPASLTAAAAGIHARLGRVDLVVNNAGL
                     ALPDLLGGAAGDNWQRMIDVNVTGAFAVVETFVPDLLAAAAERGHADLVNISSAAAQSV
                     LPGFAAYAASKAAFSHLSRNLRAQLSPADVRVTNIEPGTVDTELRDHIDEPAISAAVQE
                     AVASIEGLPSGSDIAELIAFAVERPRHLNLPQISVLPTREA"
     CDS_motif       17492..17581
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DMA15_RS35945_0001"
                     /evalue="4.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="DMA15_RS35945"
                     /protein_end="50"
                     /protein_start="20"
                     /score="16.2"
                     /tool="antismash"
                     /translation="VVTGASSGIGEATAHKLAARGAHVALLARR"
     aSDomain        17492..18001
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS35945_PKS_KR.1"
                     /evalue="3.50E-14"
                     /label="DMA15_RS35945_PKS_KR.1"
                     /locus_tag="DMA15_RS35945"
                     /protein_end="190"
                     /protein_start="20"
                     /score="45.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVTGASSGIGEATAHKLAARGAHVALLARRADRLDEHVARIEAAG
                     GTALALPTDVTDPASLTAAAAGIHARLGRVDLVVNNAGLALPDLLGGAAGDNWQRMIDV
                     NVTGAFAVVETFVPDLLAAAAERGHADLVNISSAAAQSVLPGFAAYAASKAAFSHLSRN
                     LRAQLSP"
     gene            complement(18316..19074)
                     /locus_tag="DMA15_RS35950"
                     /old_locus_tag="DMA15_35935"
     CDS             complement(18316..19074)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS35950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_35935"
                     /product="hypothetical protein"
                     /protein_id="WP_125516985.1"
                     /transl_table=11
                     /translation="MARKPRVPYRSWPLALTASAVLLAGGCGGGGSAEGDLGKGTQDGS
                     ETTESFEPPEPTKAAVDPPHGGQTPDKGWESEAEDAVAVVDNFWSAHWNDHFTGAYTSP
                     TVFGTYIPGTAEAPSCGGEPAVPDNAFYCTTDDFIAWDAALMSKGYEKGDAWIYLVIAH
                     EWAHAVQNRVDGLAVEAAELQADCLAGAALYGSADLQFEDGDSDELGAALTELADDTPW
                     TNSRDHGDAEQRINAFSTGGSDGVAACLPE"
     gene            complement(19157..20425)
                     /locus_tag="DMA15_RS35955"
                     /old_locus_tag="DMA15_35940"
     CDS             complement(19157..20425)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS35955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_35940"
                     /product="hypothetical protein"
                     /protein_id="WP_125516987.1"
                     /transl_table=11
                     /translation="MTGRPSRFSLRIRLQIALIAIIVGATLLATWQFSQSSGAYQDAMR
                     QEIRRQAAMVEDIRAVYADEGPQAMRVAAAEARADGLRPIRNEGRLAASEYTLAAQTAF
                     HLPRSARRDHLLGNGAYRYKDLGYDLPQRLADVQQRSPGLYGLTPDAQMRDGDRWAAWG
                     TASAAGGTLAVLVAMCAANVLRPRRWQRTPTASGRRVLRRLEIIPQPATASAGHRRSAL
                     FNLLACVLPLLLPLGQILAAGGEQRAQAEAARSAVRLSASIEAHGLRTAFLTEGLRTAL
                     AAEAGALARELAVWDTGISPSDARHERVMAAVEGTIAVQIRSIAKYMGRVPVAEDRVDM
                     TTVTALSREPKKLGAARAEQNRQVDLAEQAGRRSLLLSAATAVAVVAQILTVAAFAGGR
                     RRWLWWPAVGVLASTALTAVAFT"
     gene            complement(20422..20793)
                     /locus_tag="DMA15_RS35960"
                     /old_locus_tag="DMA15_35945"
     CDS             complement(20422..20793)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS35960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_35945"
                     /product="hypothetical protein"
                     /protein_id="WP_125516988.1"
                     /transl_table=11
                     /translation="MLPATLVGVWESRPDGGSGTIAYRFTADGRYKYVGLLFYPNTDGD
                     DVQITFVAQGTARVEGDRLFLNPTTATKSRQDPGDPAGDYTDQPAERSPERHGWSVSGD
                     VLTLTDVKGAQIAYDRQSL"
     misc_feature    complement(21066..21079)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    21109..21121
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    21278..21295
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            complement(22118..>22213)
                     /locus_tag="DMA15_RS35965"
                     /old_locus_tag="DMA15_35950"
                     /pseudo=""
     CDS             complement(22118..>22213)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036771.1"
                     /locus_tag="DMA15_RS35965"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35950"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="RTRYERRADLHQGLLELPCSLICLRRLRTAF"
     gene            complement(22232..22861)
                     /locus_tag="DMA15_RS35970"
                     /old_locus_tag="DMA15_35955"
     CDS             complement(22232..22861)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005321989.1"
                     /locus_tag="DMA15_RS35970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35955"
                     /product="hypothetical protein"
                     /protein_id="WP_125516990.1"
                     /transl_table=11
                     /translation="MASLPLSARRTATATIAALVAGLTLCTSSTASSAEQRTDHRRPGA
                     ARIVGSGDFVLPYLSDNDVRSFSFDAVAAPYSIPRPKIPTGLPVDARGTVRISHHSADQ
                     NVTYTSEGQVECLVTGPNTATVTALITKVSHEETGSLGKRVGLSVYDGGKGGKADRVGF
                     SWNGVNLLPNSEDAEVGTCMAPAPYAPVVKGGYTVTHAELAPLPRP"
     misc_feature    complement(22951..22964)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            23331..>23570
                     /locus_tag="DMA15_RS35975"
                     /old_locus_tag="DMA15_35960"
                     /pseudo=""
     CDS             23331..>23570
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012948683.1"
                     /locus_tag="DMA15_RS35975"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35960"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRADLVPDDLWEQVAPLLPPPPERRHRHPGRLRVPDRVALAGVMY
                     VLRTGVAWRDVPAETVGCSGVTAWRWLRDWTEAGL"
     gene            complement(23710..24876)
                     /locus_tag="DMA15_RS35980"
                     /old_locus_tag="DMA15_35965"
     CDS             complement(23710..24876)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905653.1"
                     /locus_tag="DMA15_RS35980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35965"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_240660122.1"
                     /sec_met_domain="PF00881 (E-value: 1.3e-15, bitscore: 56.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPRAAEAPAPPTRSAGGSGADGGSPSGPVHYRRSPDLLLEWQDE
                     AGPVLVDCRRWRRFTARPRLLALLNALDRPLTTEEIHARWGGSAPNGEGNGEAELAATQ
                     RALDQLSAAGIIRSSAHTVQAPQGLTPYELAAHARAGHGPAANTQQGSPPPARLRHPDS
                     TETVRLTDSDELPSRPLREVLTERRSIRDFASSPLPLGHLAVFLARSARVRGPLGPLGF
                     QQTQRPSPSGGGRHSVETYVIARKVSGLTPGAYHYDPFDHTLNRLAPWDDELAAVLNTT
                     VTMPAYMEHPPPASLLLASHAARTGWKYEGLALSLIYRDAGCLLQTLCLTATDLGLGAC
                     PTGTMRPANQIAFLKCHHDGLLHVGNLALGIPGPDRDIAGRPVGPRSS"
     gene            complement(24925..27105)
                     /locus_tag="DMA15_RS35985"
                     /old_locus_tag="DMA15_35970"
     CDS             complement(24925..27105)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905652.1"
                     /locus_tag="DMA15_RS35985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35970"
                     /product="YcaO-like family protein"
                     /protein_id="WP_125516992.1"
                     /sec_met_domain="TIGR03604 (E-value: 7.1e-79, bitscore:
                     264.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6.3e-67, bitscore: 225.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAHAPTELRPDVSLVPRGDHLYVCASTGTLRVPVRVPAPGTGSE
                     AVRADAVPERVVRGLRSRGLAHQQGQSVHPLYGEMTALRAGRPVAVARQGLGGEVSALL
                     ERAGVPTVADDRTSPVAAAVLPLSLPEEQLVRRVASALEAGTPLVTYLDTPTRFFHATL
                     RPPHTPCPVCLVRRLRANHIWQPIAGLPLTVLFGASDSGGWPSTAVASGLLAHEVLTLL
                     GTGTRHGEDEAAESGKTPEDEITQSRVRLTEIEHGSLARTEHDLFHLPGCPACAAHAVP
                     PRREDEPTEIDNTLSWERMRGAVDTLTGMVLRLLVDEQDEAIGKATYARTAGMTKTHWF
                     SPVTAEARGGAVKNDPVTARVCAVGETLERYAAGVYDPESLVRASATALGSEAVDPRTL
                     PLGSAAEYARHTRLAPCDPDAEIDWVPGRSLLTGHTRYVPACAVYLPYRFPPGHRAWYD
                     PISTGLAAGGSYHHAVHGGLMEAVERDASVIFWENRLVLPTLDLDGLPEGPARRIVERM
                     RAQGVTVTAKDLTTDLGIPVVGVRFLRHTERRPVVTHSARADLDPHAALLGALEEGCLG
                     WAGARLWQENLDAGETIPEPDEVLTTLKDFSLFYWAPHRLTHLAFWDEGPLRPVAARRP
                     SPGLPADVTEATRRLAARGHEAIAVDITPIDVAECGVTVVRTVVPGLCPITLRSDFHRR
                     GGPRVFQAPLAMGVRDTALTEAQLNPLPLPFL"
     gene            complement(27235..27393)
                     /locus_tag="DMA15_RS35990"
                     /old_locus_tag="DMA15_35975"
     CDS             complement(27235..27393)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016905651.1"
                     /locus_tag="DMA15_RS35990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35975"
                     /product="azolemycin family RiPP peptide"
                     /protein_id="WP_125516994.1"
                     /transl_table=11
                     /translation="MQQTKQPVEIDGDALFEEMAIPESEEAFAGHSCLSWAAPHSMDVL
                     TPTSGGS"
     gene            complement(27705..28457)
                     /locus_tag="DMA15_RS35995"
                     /old_locus_tag="DMA15_35980"
     CDS             complement(27705..28457)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714840.1"
                     /locus_tag="DMA15_RS35995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35980"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_125516996.1"
                     /transl_table=11
                     /translation="MSETGGTGTAGRKGAGTRTAPGAGSPRERYRTQVRAEIKERAWEQ
                     IADAGASALSLNAIAKRMGMSGPALYRYFGSRDELITELIRDAYRDLADTFRADADNGR
                     GDAEDGTGTASGADLASLAHAMRRWARADPHRYFLVFGTPVPGYHAPDDVTGIASEIMA
                     ALLDACAKLPARTSAEVDDQPFDRHIKAHGQWAGEHPATPAQLHRALSFWTRLHGVLSL
                     ELAGHFTGMGFDAEAFFEAELEGLLAPA"
     gene            28615..29646
                     /locus_tag="DMA15_RS36000"
                     /old_locus_tag="DMA15_35985"
     CDS             28615..29646
                     /NRPS_PKS="Domain: PKS_ER (22-341). E-value: 2.1e-44.
                     Score: 143.8. Matches aSDomain:
                     nrpspksdomains_DMA15_RS36000_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669955.1"
                     /locus_tag="DMA15_RS36000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35985"
                     /product="medium chain dehydrogenase/reductase family
                     protein"
                     /protein_id="WP_125516998.1"
                     /sec_met_domain="ADH_N (E-value: 3.1e-06, bitscore: 25.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.8e-19, bitscore:
                     67.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATELVEVVLPGRVEPEGLELRRGPLPTAGAGQVVVEMEAIGVS
                     FAEQQMRRGRYYDQPPFPFVPGYDLVGTVLAAGPGAAPSLVGKRVAALTKTGGWASHVL
                     LDAADVVEVPGGVGAAEAETAVVNGITAWQMLHRKARVRAGQTVLVHGANGGVGSLLVQ
                     LALAAGARVIGTASARHHEALRRLGVRTIDYRTEDVPRRVGELAPGGVDAVFDHVGGRS
                     VIDSWGLLAPGGTLVSYGTAATRDDTGSKQWPVLKILGRVWLWNGLPNGRHAYFFNVWA
                     GRAFGKDRFRARLRADLGEVFAALERGEITASVAAELPLARVADAMRLAESGTVSGKVV
                     LTP"
     aSDomain        28681..29637
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS36000_PKS_ER.1"
                     /evalue="2.10E-44"
                     /label="DMA15_RS36000_PKS_ER.1"
                     /locus_tag="DMA15_RS36000"
                     /protein_end="341"
                     /protein_start="22"
                     /score="143.8"
                     /tool="antismash"
                     /translation="RRGPLPTAGAGQVVVEMEAIGVSFAEQQMRRGRYYDQPPFPFVPG
                     YDLVGTVLAAGPGAAPSLVGKRVAALTKTGGWASHVLLDAADVVEVPGGVGAAEAETAV
                     VNGITAWQMLHRKARVRAGQTVLVHGANGGVGSLLVQLALAAGARVIGTASARHHEALR
                     RLGVRTIDYRTEDVPRRVGELAPGGVDAVFDHVGGRSVIDSWGLLAPGGTLVSYGTAAT
                     RDDTGSKQWPVLKILGRVWLWNGLPNGRHAYFFNVWAGRAFGKDRFRARLRADLGEVFA
                     ALERGEITASVAAELPLARVADAMRLAESGTVSGKVVL"
     CDS_motif       29047..29109
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DMA15_RS36000_0001"
                     /evalue="6.70E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="DMA15_RS36000"
                     /protein_end="165"
                     /protein_start="144"
                     /score="18.7"
                     /tool="antismash"
                     /translation="GQTVLVHGANGGVGSLLVQLA"
     gene            29738..31159
                     /locus_tag="DMA15_RS36005"
                     /old_locus_tag="DMA15_35990"
     CDS             29738..31159
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604352.1"
                     /locus_tag="DMA15_RS36005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35990"
                     /product="carotenoid oxygenase family protein"
                     /protein_id="WP_125517000.1"
                     /transl_table=11
                     /translation="MTDTNTAAGAGIGTGAHAKTSTDTGADPHQLPYLTGHFAPVPDEV
                     TAWGLTVRGALPPELSGRYFRNGHNPGPGQKPTHWFRGAGMLHGVRLGGGRAEWYRNRW
                     VRTPALEGAPLVRDDGTMDLTAGVAGTHVIEHAGRILALQEANLPFEVGPELDTLGAYD
                     FRGGLTTAMTAHPKEDPETGELHFFGYSPLAPYLTYYVADAQGELIRSRVVPGAGPTLM
                     HDFGLTAHHTVWLDLPVVFDAEEHSGIPYRWSDTYRPRIGVMPRDGSAEPTWYEVEAGA
                     MIHVTNAYEDAAGRIVVEGPRYDRSSWESSWKWWTGAPGHPPVPVVGSMRHRWVLDPAT
                     GTAREERLDSLVTEFATINEALTGSAHRYTYTVAFPGAGLERYALVKYDALTGQRQIAD
                     AGPGRMYGEPYFVPAAEGTAEDDGYLMTLVSDLARDASELLILSARDITRPPVAAVELP
                     RRVPAGIHGSWIPDA"
     gene            complement(31213..31986)
                     /locus_tag="DMA15_RS36010"
                     /old_locus_tag="DMA15_35995"
     CDS             complement(31213..31986)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059309.1"
                     /locus_tag="DMA15_RS36010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_35995"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_240660123.1"
                     /transl_table=11
                     /translation="MLEKGLLVAWSTRQLAELAGTTTKTVRHYHDLGLLEEPERAPNGY
                     KQYGVSHLVRLLRIRRMTDLGVALADVPLVESGDEKALRILRHLDVELAADIARKQRMR
                     RELAAVMGNRAALDMPPEFRTLADDLPEAQRSLLLAYSSILTPEAMAALREQLSGPRGT
                     LEADFAALDEDAPEEVRQRLAERMAPEVRQQHRDHPGLADLGVSSRRETAVAESVVVHA
                     LLEFHNRAHLDVLRRVHAILFEDDITEGDSKDARG"
     gene            32132..33643
                     /locus_tag="DMA15_RS36015"
                     /old_locus_tag="DMA15_36000"
     CDS             32132..33643
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (92-275). E-value:
                     8.1e-21. Score: 66.7. Matches aSDomain:
                     nrpspksdomains_DMA15_RS36015_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014158379.1"
                     /locus_tag="DMA15_RS36015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_36000"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_206302900.1"
                     /sec_met_domain="PF00561 (E-value: 2.5e-25, bitscore: 88.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRQGSVGQSLALVAVLGLGGSPAPVPAAAEEPRTPQVEWGQCPD
                     DVVAEAAPTALRCATVPVPLDYADPEGEQIDLTVSRLAAADPDKRRGVLMLNPGGPGGS
                     GLALSALLVAHGLPSSVTERYDLIGMDTRGTGHSTPVSCGFTTDSPYYSNIPPYAVDDA
                     AVTAQAKVAERAAEQCADNDHDGRLRHLTTANTARDLDRIRAALGEEKTSYLGYSYGTA
                     LGAAYASMFPEHADRIVLDSNIGDTHLDRDGLRRYALGTAQTLPHFAKWAARRHDSYGL
                     GRTPHQVRASYLTIAGTLDKAPVAGIDGGLFRLLTFGHLFKKTQYPQLAQTWQAILEGD
                     ETALRGLPAAQEEAADGAPSPTDNALTVFLSVTCNDVEWPEDVNTYRRGVAEDRERYPL
                     FGAATANITPCAFWPHAPAEPPVKIGTEGPRNVLLLQNRRDASTPHRGGKMLREKFGDR
                     ARLVSVDDSGHGVYVLGNNSCALNTTTRYLVEGEMQVKDVFCRAD"
     aSDomain        32408..32956
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS36015_Abhydrolase_1.1"
                     /evalue="8.10E-21"
                     /label="DMA15_RS36015_Abhydrolase_1.1"
                     /locus_tag="DMA15_RS36015"
                     /protein_end="275"
                     /protein_start="92"
                     /score="66.7"
                     /tool="antismash"
                     /translation="VLMLNPGGPGGSGLALSALLVAHGLPSSVTERYDLIGMDTRGTGH
                     STPVSCGFTTDSPYYSNIPPYAVDDAAVTAQAKVAERAAEQCADNDHDGRLRHLTTANT
                     ARDLDRIRAALGEEKTSYLGYSYGTALGAAYASMFPEHADRIVLDSNIGDTHLDRDGLR
                     RYALGTAQTLPHFAKWAARR"
     misc_feature    33722..33737
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            33802..34371
                     /locus_tag="DMA15_RS36020"
                     /old_locus_tag="DMA15_36005"
     CDS             33802..34371
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560144.1"
                     /locus_tag="DMA15_RS36020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_36005"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_125517002.1"
                     /transl_table=11
                     /translation="MVRAGLSPERLTLAGAELADEAGFGQVTLSALARRFDVKPASLYA
                     HVKNSHDLKTRIALFALEELADRVADAVAGRAGKDALTAFANAYRDYARAHPGRYEAAR
                     YRLDPQTAAASAGVRHAQMTRALLRGYDLAEPDQTHAVRMLGSVFHGYASLEAAGGFDH
                     TDIAAQQSWAWTLDCLDTALRSRSAS"
     gene            34449..35627
                     /locus_tag="DMA15_RS36025"
                     /old_locus_tag="DMA15_36010"
     CDS             34449..35627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020124864.1"
                     /locus_tag="DMA15_RS36025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_36010"
                     /product="GDSL-type esterase/lipase family protein"
                     /protein_id="WP_125517004.1"
                     /transl_table=11
                     /translation="MSTEQKLITTPITADFLRGHLDVEETPHGLLPHRLPARARRQIPD
                     DQLAVAEAQPSGVRLAFRTSATTIRLDTLPTKRVYRGFPPPPDGVYDLLVDGRLTAQAT
                     VDGGNLRTITDMQTQTAEFTPGPVGTAHFTDLPAGEKDIEIWLPHAEITEVVALYSDAP
                     VEPAPKTGRRVWLHHGSSISHGSNAVSPSTIWPALAASAGDVELINLGFSGSALVDPFT
                     ARAMRDTRADLISLKLGINVVNGDAMRLRAFAPAIHGFLDTIREGHPAIPLLLVSPVLC
                     PTHENTPGPLMPDPSGGTLKFKATGDPAETAAGRLTLTIVRDVLAGIVEQRSAEDPNLH
                     YLDGLDLYGESDHDEFPLPDGIHPGPEGHRRIGENFAKLVFADNGPFALTPG"
     gene            complement(35663..36439)
                     /locus_tag="DMA15_RS36030"
                     /old_locus_tag="DMA15_36015"
     CDS             complement(35663..36439)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356715.1"
                     /locus_tag="DMA15_RS36030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_36015"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_125517006.1"
                     /transl_table=11
                     /translation="MAWSTREMAELAGTSLRAVRHYHDIGLLDEPERRSNGYKQYGVSH
                     LVRLLRIKRLTALGFSLSQIADMREGPDSAPDPRDLRALDDELAATIERLQHARAEVGA
                     LMRRTAASDLPLSLASLDETAEFPDPDRSFVTVLGTVLGPNGMDAYADLLHEQPQPVAR
                     ELDELPADADEQTRQSLAERLVPYVRGLQVKHPGLHDLASDAPRGRRHADRTIGKAIAD
                     LYNPAQVDVMRRLQKLLSDSGCEADRPESTDKAREA"
     misc_feature    36554..36568
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    36555..36567
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(36561..36575)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.91"
                     /tool="antismash"
     misc_feature    36562..36578
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.94"
                     /tool="antismash"
ORIGIN
        1 gacgtgaccc cgaacgcgtc cgtgaacgcg ttgtcggcgc gccgcttcaa ctcctccccg
       61 gcggcgccgg gcagggcgcc ggccactccg acggcgtcgg ggaggccttc gcgcgcggca
      121 tccatggcct tggggtccac cccggcgacg gggtcgtcca tctccctgcg gaagagcgcg
      181 gacgccacgc tgcccatgat cgccacgctc agtccgttgc cgagttcgta ggaggtctcc
      241 tcgatgcccg cggcgccacc cgcggtatcc gcgtcggccg tcgacatgat ggcgtccgac
      301 gcggccgtca tggcgcaacc cgcaccggcg ccgatgcccg cgagggcgat ggcgaacacc
      361 cagtactcgg tgtcgggctc gacgttcatc aggacgaaga acgcggcgcc gatcaggccc
      421 atcccgatca tcatggcgta ccgcgtcccg tacctcggga cgatgacgga catgatcggg
      481 gccccgatca tggtggccag gagcagcggc agcagccgaa ggcccgactc catcggcgag
      541 gcgccgccga tgaactgcca gtgctgcgtg agcagcagca tcagcccgcc catgccgaac
      601 atggcaagga ccacggacac caccgccacg gagaacgcgc ggtcgcggaa gagcgtcggg
      661 tcgaagagcg ggtcgcggat gcgcagcacc cgcaccacca gggcggtgag cagcaccagg
      721 ccgagaacac ccgtgatgat cgtctgcgcc tccaggccct tggcgccgcc gtgctggatg
      781 gcgtacacga gggagatcag gccggtgacg gagagcagcg ctccgacggt gtcccagcgc
      841 ggcggattcg gatgcctgga ttccgggacc agggtcagcg cggcgatcag ggcgaggacc
      901 atgatcggca cgttgatcag aaagaccgag ccccaccaga agtgctcgat catgacaccg
      961 ccgaccaccg gcccgaccgc ggcaccggcc gccgacatgg tggcccacac ggcgagcgcc
     1021 accgtccgct ctttgcggtc ggtgaagacg ttccggatga tcgagagcgt cgacggcatg
     1081 atgatcgccg cgccgatgcc gagcagcgcg cgggccgtga tcagcatcgc gggcccggtc
     1141 gcccaggccg cggcggccga tgcggcgccg aagacgatga agccaaggca caggaaacgt
     1201 ttgcggccca cgcggtcgcc gagcgtgccg cagctgatga gcagaccggc gacgacgagc
     1261 gagtagacgt cgacgatcca cagcaactgc accgatgagg gtcgaagttc ggtgctgagc
     1321 gtgggcagag ccacgttcag caccgtcagg tcgagggcga cgacgagaag gctcagtgag
     1381 aggaccccca gcaccgccca tcggtttttc gccccgggga cgccgccgtc gtcaccgccc
     1441 tcacctcctc cgtggcccgc gccctgctgc tcatgcacca cgccgtccat gactggcctc
     1501 cttcgggatt ccgtcaactg gtctcgtacg tcataccagc tatcgtacgt cgtacgagac
     1561 tgcgttagca taggactgtg aatgaaactt ctggacgaga aaacacaccg aaaggccaac
     1621 ccggctcgat ctggctgcgc gaggtgaagc agcggccggc gaggcagccg ctgagccgtg
     1681 aacagatcgt gcaggcggcg gtgcgtctcc tggatgaagg gggtgtccgc aatctgcgca
     1741 tgcgtcagct cgcggactcg ctgaactcgg caccgatgtc gttgtactgg cacgtgtcga
     1801 ccaaggacga cctgctggaa ctggccgtcg acgcggtctt ccccgatccg ccgtcccggt
     1861 ccggcacggg ggactggcgc gacgacatca aggcgggcgc gacggatctg ttcgaggtgc
     1921 tgctgcggca ctcctggatg atcgagctga tgggcggtca tcccccggtg gggccccgcg
     1981 ccctggcgca tacgagcgcc atcatcgaga tcctggagca ggcccacttc tccccgaggc
     2041 agctggactc ggcgctctca gcgatctact actacaccgt gggcgccgcc ctgtccgagg
     2101 cgtcctggca ggcgatggcc cgccagagcg ccgagagcga ggaggagtgg gtgagccgcc
     2161 tcggccccta cctcggcatg gcgacccagt cccacccggc gtccctgggc gactacgtca
     2221 agcgcagcgc ttccagcagc acgggccagc ggttccacga cggcctcgaa tgcatggtgt
     2281 ccggtatggg gcagatgcgt tccgaggact cctgaggccc cgacacgccc ctcggcctgc
     2341 tcccggccgt gctggtcgtc ctcctggagc aggccgccgt cgacgatgac gccataggcc
     2401 ggccgccgac ggctgtcggc ccacctcgac ccggaacgcg agcggttggc ctcgccgcga
     2461 cctgccgcac gacgggactc ctcgccggca tcgtgggagg gccgttccgg cgaacggagc
     2521 gtgaccctcc acggcggcgt acagcgtggc gcccagggac cagaggtcgg actccgccgt
     2581 cgcgggcagg ccgcggcgtg agcgcgcctt gtgcctcgat gaggtcggcc agggacccgc
     2641 cgtccaccaa ctccatgatg atccagggcc gctgctcgtc gtgggcctgc cggacggcgc
     2701 ccatgccacc taggccgagc agtcggctca accggtagcg gcccgcgagg agttgcccgt
     2761 gatcgtcatc cacgtagagg atataggtca acaaggctgc cgttccccgc tgcttcctct
     2821 accggctcgc gaggtggccc tccagctcgt cgaggactgc gatcgttccg tcctcgctct
     2881 cgatggtcct tgagatcttg gcgcaccgct cgcggtaccg cttgtcctga agcgccgtgc
     2941 gcagggtggc ggagaggctg tcggccgtca ggcgccgagc gctgacgtac ccgggggaga
     3001 ggcccagggc ggtcaggcgg cgggcccaga agggctggtc gagtacgaga ggtaccggca
     3061 cggcgggcac accggcccgc agaccggcac ccacggtccc cgagccggcg tggtggacga
     3121 gagcggacat gcgggggaag agccagtcgt gcgggcactc gccgatcgtg agaatgccgt
     3181 caccgtggac gtcgaggccc tgccagcccg cctgtaccac cgcacgcacc cctagtcggc
     3241 ggaccaccga cttgatcatg tcgctgagcg gctcggcgcc cccgatggac agacttccga
     3301 agccgaagaa gacgggggcg ggtcccgacg ccaggaagtc ggccagcctg tcgtcggggc
     3361 gccacgtgct gtccgtggtg ggccaccagt agcccgcgca cttgtgccct tgggggagga
     3421 cgagtctctt cggcagcagg gcgggactga aaccgtgcag gacgcgtgct ccgcgcagaa
     3481 tgccactggg agtcctgaag cggcggcttc gcgcgcccag ttcacgttgg agccaggaga
     3541 gggcgggagc gtacaaggga tgcgtggccg cccacaccaa cctctcggcg gctcggtacc
     3601 cccggccggt ggccgtattc gcgccggcct gcggcacgag catgccggga gacgccgcgt
     3661 agatcccgat acacgtgcgg ccggtacctt cggcgatcac ggcgcacagc ggatgcgtca
     3721 tcgggtgggc caggatgatc tcggcaccgt tggtgaccgc ctccaggacg ccccgggcga
     3781 tgacttgggt catttcctgg gcgttgcgtt tcctgcgtct gagccgggcg ggactctgcc
     3841 agcggtcgaa ccgctcggcg gagagcgcgg actcctcgtg acgggccagc ggcaggatgt
     3901 ggacgggcat cccacccgct tggaagcgcg ccgcgtggcg ctcggaagtg gcggctgtca
     3961 cctcgtggcc cgcagccttc aggcgggctc ccaagcccgc gtagggcagc acgtccccgg
     4021 tcgagcccca ggtcaccaac aagatccgca tgcggccgag tatgcacagg ggggctgacc
     4081 gcacgacgga ccagaacgcc cgcatccccc agaagagtgg ggtgcggcct caccttgacg
     4141 ccgtgtgcgt gaagcggagc acgaaatcag cccgcattcg cggaggctta ggtatgtatg
     4201 cgggatgtct ctcagcaccg acaccgccgt cacggtggct gacaccaccc tggactaccg
     4261 cgggttccgc tacctcgccc gcacgtccac cgccggatcc tccgccaccg aaccgctcgt
     4321 cgtactcggt ggctcctcgc aggaccgttt ctcctggatg cgttatgagc gatggcttct
     4381 gccgcacacc accgtggtga ccttggaact gcccggctac ggaggcgccg acgcgctgcc
     4441 cgtcgaacac ggcatggact tcctcgccga cgccgtctgc cacgcgaccg aagcccttgc
     4501 cctggggcgg gtcaacgttt tcggtgcctg cttcggagcc tccatcgctc tgcgcctcgc
     4561 gcaacggcac cccgaccacg tcgcgcgtct catgctcgga ggcacagcgg tcgagatctc
     4621 tcccgagtac accgcgtcgg ccaggcgatg gcgtcgcatg gtcgacgacg gccaattcga
     4681 cgagatggcc caggacatgg tcgagcagtt catggcccca ccgggacacg ggaaggtgcg
     4741 gcgtcaagcg gcggtggcac gcctgatgcg gcagaggttc gcctgcctca ccgcgcgtga
     4801 gctcgccatg gacatcacac accacgaacg tctgctgacc cacccctgga gcctgcccgg
     4861 gctccccgtc tccgccccgg tgctcgtctt caccggcgag cacgacacca tcacgccgcc
     4921 cgaggtgggg cggagagtcg ccgcggatct cggtgcccgg ttcaccacca tcacggagtc
     4981 cgaccatctg gtccagatcg aacgcgacag tgacctggcg gacctgatgg cccacttctt
     5041 caccgaccgc gcactggacc agctccccta cctcaaccct gtcgagcact tcacccgcac
     5101 ctgagggcga cgtgccggcg agaacgggag cgggcttcgc atctgcggtg ctgtcgagca
     5161 gagcgccgga cgtggacggc atggccgtca cttcgtgggg cgacctcgaa gcgcgcactg
     5221 accggccccc tccgaccggt caggtcaacc acttcggcgg cgccgggctc agcagtccgc
     5281 gaagacggag ctcatcacgt cctcgtccgc gcgcgcgagg tcacccttga accagccggg
     5341 gacggtgccc agatagccac tgtagttgct gtgcttgtag atgtggatgc gggtgggcgt
     5401 ccggttccag gccgaactcg cccgatcctc gaaccacgag ggcaccttgt ggtggccgca
     5461 gctcggcacc acccacaacc agcccccgcc cccgtcgttc tggaagaagc aggagccgct
     5521 accgcactcg gaccaggccc gggcgacgta atcgccgcca ctgagccggt acaggccctc
     5581 cacgcccgcc accgccgtga cgcgggtttc ctcggcgctc gccgccgtcg gcacggcgag
     5641 tgcgagaacg gccgtcgtcg ccgcgacgca cgctgcgatc ctcttgcgca tgtctcctcc
     5701 tggagtcgct ggaatgccgt gcgttcactg tgacccgtgg cggcccgccg atcgtcggca
     5761 acgagcgcac acttgctgaa catccagcgc acgcgccccc gtccgggccc gtacctcgct
     5821 cggcgggaag ccgtacgccc tgcggaaggc ccggctgaag tccgcggggt ggcggaatcc
     5881 ccagcgtgcg gccgtcgcgg cgatggtgcg cgtgccgagc gccggatcgg ccagctccgt
     5941 gcggcagcgc tccaggcgca ggcgccggat catggcgccc acggtctccg gttcgttccg
     6001 gaaaaggagg tggaggctgc gcacggagag gtggtggtgg gcggcgatgg ccgccgggag
     6061 cagttccgga tcgcccaggt tctgctcgat gaagatcttg atccgggagc gtaccgcggc
     6121 cctgcgggtc tccgcgggca acgcctcctg ggccccgagc cgccccgcca gtacggtcgc
     6181 ggccagatcg atcccgatcg caccgagccg ggccaactcc gccgggccac aggtgtgggc
     6241 ggcggtcggc agcccggcca ggtacgagcc gagcagcgcc gccgaccccg aaccggcgcg
     6301 ggtggacagc ggctcggcca gcagccggtc cgcccggccg ccggccagcg gcagtaccgt
     6361 gcgcggcagc cgcagcagcg tcagccgggt ctgccggcct cggtcgagga agtcgcagac
     6421 gagcggcgcc gaagtggtga acagactcat gtcgccgctc cccaggcagg ccacgccgcg
     6481 cgcctgctcc agccggatgg ggctcccgcg gacgaggacc aggtagtact cctccgggtc
     6541 atggcggcga atgtgcacgg gggaacggcg ggccaccatc ggggagaagg cgaaagcggc
     6601 tacctggctg tgcggcatgc ccacagcctc cacgctgccc ctgaaacggg gcgcgtgcgc
     6661 gctgtggatc gctacgggca tgacctcggc gccgaccatc tgggcccacc agtcgaaccg
     6721 ctccggcgcc ggaaccccgt cggtgctcgc ggacaccacc ggcccgtccc cgccatcggt
     6781 ctgccgcgcc gcctcattga tgctggacat tcaacgatgc tcacggctcg ccgccccgcc
     6841 ggaaagccgc gggccggaca gatgacggca agacgcagac gaaccccctg gcgcggccgt
     6901 ccggcggtgc cagggggttc gctcatgacc gttcagagga ctccgcgcgt ggcacgggtc
     6961 agagggccct ggccgcgcct cacgttggcg cctcccagcg cgtaggcacc ggccagcatg
     7021 gcgacggcac cactgccgac gcccaccgcg atcgccttgc ggttcttgag caccgtccat
     7081 gtcgtcgccg ccgcttgcat ggtcttctgc ggtacggcgg acagcagttc gccgcccgcc
     7141 ttcgccttct caccgagcgt cgcgcccaca gacgccgcgc ccttccccgc ttcggcgacc
     7201 gatgacttca cgtcacgggc cgctgagccg gtcttggcgg cggctccgga agcggtcttg
     7261 gacgcggaac gggccgtgcc tcctgcggcc ttggccgtgg tggccttggc gctctccgcc
     7321 ttggaccggt cggccttgtc ccccgtcgaa gtgtcaccta caggactggt tccgtttttc
     7381 gtcgattcac tcatgccctc cgtctgaccc cgtctcaccg ctcgaaacaa acgcgtattc
     7441 gtacgccgtg cgccccggcg aaccgtgaac gcacccggcc ccgaagtcag gtgccgccac
     7501 cactactccc gcgtgcgtga gcagaggggt gctgcctgcc tccaacgtcc tgatcggcct
     7561 caccactgac cgggagtcgg tctgcgccga ctacggcgcc ggcggaccga tcccgggcgc
     7621 cgtcatggac catctccgcg cctgctaccg agccgcggcg ccccgcttcg actaccgtgc
     7681 cgacgacgtg ctggtgatcg acaacatgct gctctcgcac ggccgggagc cgttcacagg
     7741 gccccgccgg atcgcgctcg ccatggcgga gccgtacacc cccaaccgct ggccccagga
     7801 cggaagaccc tcgtatgttt gcgcgttccc tccggtccaa ccgggacttc tccgtcttct
     7861 gggcggtcca ggccctgtcc gaggtcggca acgccttctc gctggtggcg cttccgctgc
     7921 tggtgctgca caccaccggg tcggcggcac agatggggct gctcacggcc gtcgcgggcg
     7981 ccaccgcgct cctcaccgga ctggtgggcg gcacctgggc cgaccgcttc gaccggcggc
     8041 tgctgctgat gctgtgcgac gccgcccggc tcgtgctgta cggcgcgatt ccggtctgct
     8101 gggccctgaa cccgcagatc tggctgctgt acgtggtcat ggcgctggcc tcggtcttcg
     8161 agacgttgtt ccggatcacc tatgtcaccg ccgtgccgaa cctcgtcgac aaggagcaga
     8221 tcgtcgcggc gaacggccga ctggaggcga cgaacgcgat cgcctacatc gcgggcccgg
     8281 ccctggccgg tgtggtggcc gggctgttcg ggcccacggc cgccgtcgcc atcaacgcgg
     8341 gcagcttcgg gatctctctc gtgggcctgg ccttcatcag gctcaggccc accgtgcggt
     8401 cttcggccga cgaggccgag aacaaggcgg cctgggccca ggacctgcgc tccggcttcc
     8461 tggtcggcgc cgcgttcctg tggcgcacgc cggtgttgcg ggcgctcacc ttgctgctga
     8521 ccgtcaccac cttcctcagc ctgggcatga ccgatgtctt catctaccac ctgcggcacg
     8581 gtctcgggca ggacgaacgc acggtgggct acgtcctcgc cctggccggg ctcggcacct
     8641 gcgtggccgc cgccgcgacc gcctggctgc gccgctcctg ggggttcggc acctgctggc
     8701 tcggcgcgat gggtctgtgc tcggtgtcgg tgctggtact gggcggcacc ggacaggtgg
     8761 ccgtggcgac cgtgacgatc tgtctgtact ccttcggcat ggcactcgcg ggcatctgct
     8821 cgatgtccct gcgtcagcag gtcacgccgg accatctgct cggccgggtc acctccgcgt
     8881 tctggacgat ccacggcagc ctcgcgcccc tcggcgcggc tctgctcacg gctctggtgg
     8941 gccggctggg gacacgtggg ccgctgaccg cggtggcggt cgtcttcctg gccgtggtgg
     9001 tggccgccgc cttcaccccc attcgacagc gccggccgga actgaccgcc gtaccgctcc
     9061 cgcggacacg gcccactccg ccgccaccac gagatacgcc tccctcagcg gcctgcggag
     9121 aaggtgatgt gcatcacatt tagcgaatgt ggggtactgg ctcgtacaca agaacggcgt
     9181 cagtgccagg catgcgtctc actattcgat gagggcgaag ggtgttcacg ctccgtttgc
     9241 cttcgaatcc ggcgctgggc gcgccccggt gggggtcggg gcgaaggaag gctcaccggc
     9301 ggttcggcgg tgtgagacga cctgcctctc tggtgtccgc tgagatggtg tcaggggcag
     9361 agagcggtct caattttcgg ttcacgtcgc gacgccattc attgcccgtt gtaaatgggt
     9421 gaattgaagt gcgacgtgga gtggattccc tcggactggg gctcatgagg cacgtggggg
     9481 cgcggcaaag gccattgtct tgcggcaggt tgacggcaac actgttcttc acacggagtt
     9541 gttgccacat tcccgaatcg tcgggcatcg gtgtcgacgc gtgcggaagg tgaggtgaag
     9601 cagaatgggt atgaagatga cgatgaccac ccgctgttcg gtctctgtgc gctggcagca
     9661 cgtgcgagtg gtcatcatcg tcatggtcct cgtgttcctg agtgtgatga ctcacggaga
     9721 cggtgacatg acgctggtcg acgcgctgtt gccgcgcgtc tgaggggcga gcaggtccct
     9781 ccaaaggggg cggttgccgg gagaccggtg accgccccct tcactttgtc aggctagcgc
     9841 acaaagtctt ggcgttgaag gggaatcccc tcgaaatctc cccggtgttc ttggaactat
     9901 ccggtagggg tcccggcagg cgtcaggcgt atgcgaattg aacacggcag cgggaagagc
     9961 cgtggagggg cccattcccg cagccggttt gaccaacaaa tcagctcacg cagagaaccc
    10021 tgcggaattc gctgttgccg tactcgtcag gcgaggcgat ggcgactccc tgcgcctcca
    10081 cccacgcgtg gaaacggtag gggtcgtccg ccgtgccgat gcaccacacc acccgccggc
    10141 cggtcagggc cagggacccg agcgtggcca gggacaactc caggcaggcg gcgcgtccgg
    10201 ggtaccaccg ggctgcccgc cgcaccgccg cgagggcggc tgaggcctgc tccggcgtgg
    10261 cctcccgccg gcaccaggtg cgtgcggtcc agcccaccgt acgggagacg gttctcaacg
    10321 gcagccggat gagcagcagc gcgccgagga gcacgaccag gctgagtacc gcggtcacgg
    10381 cgccgcgaag ggagcggtcg cctccgtccc gcaccggttc ggccgacatg gtcatctggg
    10441 ctgcggccag gggcacttcg gtgacgggcg gtacctcgcc caccgatggg gcgtgcccgg
    10501 cggatccgcg accgtccggt cggcggcccg cggtcgccgg tgcccgctcc gccgggggag
    10561 acggagcgtc ggccgccggg tgcgggtatg cgtgttgtcc cgccgcgggg ggcgtaaggc
    10621 tcggggcgtg cgcggcgagg aggccacggc tgatcaggtc gtcggcgagg cggcgggcgt
    10681 cctttcggat ccggtcgtgt tgcacgtccg ggtaacggcc ggccaccacc accaccgcgg
    10741 agtcgaagtt cccgctgcgg tgccattccc gccagagtgc gtgagccatg gagttcatcg
    10801 cgaagcagtg gccggaccgc acgtccagca gcacgctgcc accgtgcggc gaggtgctct
    10861 cgcggacgta ctcggacacg ctcagccgcg tcatgaccgc tcctgcccgc tggcaccggc
    10921 cgtcagccac aggtccgcgc cgagcaggcg gttgagcgcc gggaaggggg cggccagacc
    10981 cgcgaccgcc cgttcgaccg aggcgatcac ccgcaagggc tcgatgattc cgaggtcggc
    11041 cagcggggat cgcaggagcc gtgctctgat ctgtgtcgct gaccggcgga cgccgtggta
    11101 gttctcggcc gcgtagtcgc ccttggtcct gcgccgcagt acggggtcgg ggaccaggcc
    11161 ggtcagcgcg gccgccagca gcggcttggc ggcgaacggg tcgatgcggt gcggcaaggg
    11221 gaggcgggtg caggcccgta cgacctcgct gtccaggaag ggcgcgtgcg gccagatgcc
    11281 ggacgcgcgt gctgtggagg tgaactgagc ctgcacggcg gcggaggtgc gcagctcgca
    11341 caagactgcc cgggtgcctg gtgtcgcggg ccccgaaggg gatacgaggt cggtcgatcg
    11401 ggcacgctcc tcggccagtt cggccaggtg ccgacgtgcg cgggtggtca gccagaccgt
    11461 ctccggcccc ggggccggcc accaggccac cgcgtccgcc cactgcggcg gatggtccag
    11521 ggggtcgtcg agatgggagg cgagtccgct catcgcctgg tgcaggggag tgcgggcgag
    11581 gcatctggcg cgcaggatga cgtccgccgg ggagagctga cgtatgcggg ccagcgcgcg
    11641 cccgtcgctg aggagtcggc gcagtccggc tgtggccgcg atgtcaccga ggtaggaagg
    11701 gggagcggcc agtagtgcgt cgccgccctc gccggtcagg tgaatgccgg ggccgccgcg
    11761 cgcgatgtgg tccagccgca gctgttgtcg ggcgccgatg actgccgccg ggtcgggctg
    11821 gtccgcggag ccgtgctcgg gcaggccgct gtagggcagg gagtcctcac tgccacgggt
    11881 cacggcgagc cggaccgatg gggcatgctc ggcgtgggcc agggcgtggg cgagatcgcc
    11941 tgcgggggcg tcggggtggt ggtagacgaa ggcgtccagg ggcggccggc cggtggtgcg
    12001 ggcggccagg aaggccagag aggtggagtc caggccgccg ctgaagtccg aggtgatccg
    12061 tggggcggtg tcggtacgca ggatgacggc gcgtgtgagc gctgaccgta actgggccgc
    12121 gctgtcctcg aaccgcgtgc cggggtcggg ggcgaggtcc tcgtacgtcc aaggggtgca
    12181 gtcgccggag ggggtgactc tcagcgcctg gccgccaccg agtcggcgga ttccgtcgta
    12241 cgccgtgcgc ccttccgtga gttcgggaac cgcggggcag acaatgtgcg cggcgagcgc
    12301 ggccgcgtcg ggccgggcgg ctgctccgga cagggccgcc gcggtcctcg cccgggtgga
    12361 cagaaccgtg ttctggccgt ggcgcccgta gtagagggga aactgccccg ccgggtcggc
    12421 atacgcggtg aggtggccgt cgtcctggag cacgaggagc aggtaggcgc cgggccaatg
    12481 ggtcaggcgt tcccagcggc cgtcctgcac agcccgccgc aggtcatgac gcatcgtcgc
    12541 ttcgtcggcg aggcactggc cgatggcggc cagccgggcg tgtgcgcact gcacggtgcg
    12601 gacctcaccg gggtgccagg gcccccagga ccagagcagg ggttcgcctg gccacagccg
    12661 tgtggctcca tgcggcgccg gggcaggtgc cgccgacagc agccccgcga tggtgggccc
    12721 gttggtaggg ggaagggcag gagacgggca gcgcgggtcc gtggctgcgg cggaggccgc
    12781 gggtcggggc atgacagatg tccggaacgt cagtagtagt actgggcatt ggcatcggcg
    12841 ctcccgctgg gggagctgcc cagagccacc tcacggacat gacccaggtc gaccaccatc
    12901 ggcggttcgt aggcggccgg ttcctcgcgg gacggcacgg cctcggcctt caccgcttgt
    12961 cgcggatatc cgaaatcctc gtacggggat acggcaatgg gctcgtaagt catgaggccg
    13021 cctcgggtca ggggcatcag ctgccccggg aaagggatcg gaacgggaaa gcgtgcgccg
    13081 gccgtcccgg cgtcgtcgcg gtcccaaagt gtagcgattc tccatccgct ccaggtgccg
    13141 aaccggcccg cgatcgaagg tgctccggcc tggcagttcc cgcccttgtt tcctggcgtc
    13201 agaagggttt tcggtcccgc tgacgggtcc gctcacggga ggtcgactca ttcggacaac
    13261 ggcgctcact catttgaacg agcgcggcgg tgtcacgggg tccgcggcgc catttcgaag
    13321 aagagagggg cttgcgcggc acgccggccg tcgagtatct ccgtgagcgc ccgtggcggg
    13381 tgagatacga gttcgataat cgaaggtcta ggtgttgttg gccgcgtgct ccatgccgcg
    13441 gagtcccagg atcaaagcgc cctgcgcttc ggcccgggtg tccagttcgc tgaggtcgag
    13501 gacgaactcg gagtcctcgg cgaccgcgcc gggcagtgcg aaacggcgca aggactcctt
    13561 gcagccctcc agcagcagcg gactctgggc gagctggccg ccgatgacga cgaggtcggg
    13621 gttgagcagg ttgcacagct gggccaggga ctgcccgagg catcggccgg cgtcgtggat
    13681 cacccgcatg cagaccgcgt cctgtgcctg ggcggctgtg atgacctgtt cgagcgtctc
    13741 tggtgcgggc aggctgttgc gggcccgcgc ggcacggacc tgcgcgatca gcgcgtcggc
    13801 gccgatcacc gtctccaggc agccgcgtcc accgcactgg cagaccgcgc catgggggtc
    13861 cacggtgagg tgacccagtt cccccgccat gccgccgtgg ccccgcagca cgctgttgtg
    13921 cacgatgatg ccggcgccga tacccgtcga cgccttcacg tagaccaccg tctcggcgtg
    13981 ttcccgtgtg ccgtaggtct gttcggccaa cgcgccgagg ttggcgtcgt tgtcgatgaa
    14041 agcgcgcacg cccagccacg tacccaggtc tttcgccggg tcgtcgcccg cccgccaggg
    14101 cgggaggatc ggcggggtga agccgccggt gcgcgggttg atcatccggg gtacggcgac
    14161 gccgagggag aacacgtcgg agcggtgccg ctccgttccc tcgatcgcct catcgatcat
    14221 ctgcttgacc tcgggcagag cccgggacca gccccggctg acgccctccg agctgacccg
    14281 cgaggtcgcc cggtcgaatt ccttgtcgag tctgcgggcg accacggtca tgtggttgaa
    14341 cccgaggtgc acgcccacgc cgacatcgtt cacggccgag aggcagacct tgccgcgctg
    14401 cttggtggtg ggcacgaggc tgaccttcgc gagttcctgg accgcggccg aaacagtggc
    14461 ctgggagagc agggtgcggt gtgcgatatc ggcctgggtg ccggacttga tcgccacggc
    14521 gagaaggacc ttccggcggt tggctgcccg ggtggggccg gccgtaggca gccggcccaa
    14581 gagatcgtcc gcgttcgcca ttggcccccc agccccggta tccgcatctc gattttttag
    14641 atcgaagagc aaataatacc agcggagcct tcaattcgaa ccggcttcgg cttcgaataa
    14701 ttgaggcgca gtggggtgac cggtggggct tctgagtgcc tcgatgtgcg tcggcgatct
    14761 ctctggcggc ccgaaattgg ctgaaatttt ctagagaaag gcgctggcgt gagccttcct
    14821 ggtcaggttg ttcttcaatt gacagaacgc gaagaccccg gcggtgtaca gcatccgctg
    14881 cctgcgaccg tccggtggca acccgtctgc ctcggtgaca ggccgtcccg caccgccctc
    14941 acccttgcgg cgagttggag tgtccatgac gatggggcgc atgtcgcagc agacgggctc
    15001 ttcccggcgt acggtcctga ccgcggccgc ggccgccacc acggccggag ccgtcggcct
    15061 gcagacgggc cccgccaccg cgcgcgacgg cgggcggccc acggcccagg aaccgccgcg
    15121 cgaactgcgc gccctcctgc gggagatcga ccaccggcgc atcgaggcga cggtgcggcg
    15181 gctcgccgcg ttcggaaccc ggcacaccct gtcttcgcag gacgaccccg tacgcggcat
    15241 cggcgccgca cgcgactgga tcctcgccga gctgcggcgc cacgcgcgac gctcgggcgg
    15301 gcggatgacc gtcgagctcc agtcgtacgt ccaggaaccg ggtccgcgca tccccactcc
    15361 aacgaggatc accaacgtcg tggccacact gcgcggttcg gcctcccccg accgcttgta
    15421 tgtcgtctcc gggcactacg actcgcgcgc cagtgacgtc atggacttca cgagcgacgc
    15481 gccaggagcc gacgacgatg cctccggggt cgcgctcgtc atggagctcg cgcgcgtcat
    15541 ggcgccccgg cgcatcggcg cgacgctcgt attcgcggcc gtcgccggcg aggaacaggg
    15601 gctgttcggt gccgcgcaca tggcggagcg gttcaagcag cgcaaggccg atgtccaggg
    15661 gatgttcacc aatgacatcg tcggcagctc caccgccgac gacggcaccc gcgacccgcg
    15721 gacgatccgc ctcttcgcgg agggcgtccc ctcgtcagaa acaccggagg aggccgccgt
    15781 ccgacgtgcc gtgggcggcg agaacgactc gccggcacgc caactcgccc gcttcgtaga
    15841 ggatgtggcc gcgaacgacg cgacggggat gcgggtacgc gtcgtccacc gccgcgaccg
    15901 ctacctgcgc ggcggagacc acatcccctt cctcgaacgc gcctaccccg cggcccggtt
    15961 caccgagccc gccgaggact tcgcccacca gcaccaggac gtgcgcgtgg tggacggcaa
    16021 gcagtacgga gacctgccgg agttctgcga cttcccgttc ctcgcccgcg tcgcccgcgt
    16081 caacgccgcg accctgtgga gcctcgccca ggcccccggc accccgcgcg gcgcgaagat
    16141 cctcaccgcc gcgctgacca acgagaccga gctggtgtgg gagcgcggca ccgaggccga
    16201 cctcaccgga tacgaagtcg tgtggcgcga gaccaccgac accgactgga cccatgtgat
    16261 cgacgtcggc gacgccaccc gtcacaccgt cgacctgtcc aaggacaacg tcttcttcgg
    16321 cgtacgcgcg gtgggccgct ccggcctgcg cagccccgtg gcgttccccg cgccgcaacg
    16381 ctgaggcgcc ccgagaccgg cgagggctga gctggacggc gtgccctctt cggccgcgta
    16441 cgtgaccaga cactggtcgc cctcgtccgg caggcgcagc gtctcgcggc gcagggtcag
    16501 ctcaccagcc gtggggtgac gcagccgctc gatgccgtag gcgtgctcgc ccacatggtg
    16561 ctccgcccac agcgcgcgga agtcctcgct gcgcaccgag agttcaccga gcagatcgca
    16621 cagccggtca tcacaggagt accggcccag gtccatgcgc agggccgcga cggtaccgcg
    16681 cgcgctctcc tcccacgcct cgcggtccgg gtacaagccg cgcacggccg ggtcgaggaa
    16741 gaccagccag gccgcgttgc gctgcccggc cggcagggcc tcgaagtcgg tgaacagcgc
    16801 ccgggccgcc gcgttggagg ccaggatgtc cagtcggcgg cccagcacat acgcgggcac
    16861 ctcgccgagc gccgtgagca ggacccgcac acccggcctg accggctgcg gaacgggagg
    16921 tgtcgaagcc gggtggcgca gggcgcggat gagatggccc aggtgcgcac gttctgcctc
    16981 gtccaggcgc agggccctgg caacggcgtc gagaacgctg tcggagacgt tgtgggtgcg
    17041 gccctgctcg agccgtatgt agtagtcaac gctcaccccc gccaggtccg ccagctcctc
    17101 acggcgcaga ccgggcacac gtcggcggcc gccgaacggg cgtacgccga gatcctccgg
    17161 ccccagccgg gcgcggcggg agcggaggaa cgcggagagc tcggtgcgaa agtccatgga
    17221 tcaagtgtcc gtcacagggt ggttctgccg gacccagggt cgagccgaac cctgggtagg
    17281 cgagcggatc tcccgcagag tcactaccgc aagacaccac gggacccgca agagaccgcg
    17341 gcgacccgca ccgtcttgca ggcctcatgc acaagacaca aaggacctca catccaacac
    17401 ggtccgcacc acgcaccttc gggagaccac catgaccatc accaccgagc agaccacctc
    17461 cctcacccgc cccctcaccg gccggatcgc cgtcgtcacc ggagcctcca gcggcatcgg
    17521 cgaggccacc gcgcacaaac tggccgcccg aggtgcgcac gtcgccctgc tcgcccggcg
    17581 tgccgatcgc ctggacgagc acgtggcccg gatcgaggcg gccggaggca ccgccctcgc
    17641 cctgccgacc gacgtgaccg accccgcctc gctcaccgcg gccgccgccg gcattcacgc
    17701 ccgcctcggc cgcgtcgacc tcgtggtcaa caacgcagga ctcgccctgc ccgacctcct
    17761 gggcggggcc gcgggcgaca actggcagcg gatgatcgac gtgaacgtca ccggcgcgtt
    17821 cgcggtcgtg gagacgttcg tccccgacct gctcgcggcg gcggccgaac ggggccacgc
    17881 ggacctggtg aacatctcct ccgcggccgc ccagtccgtc ctgcccggct tcgccgcgta
    17941 cgccgcctcc aaggccgcct tcagccacct ctcccgcaat ctgcgggcgc agctcagccc
    18001 cgccgacgta cgcgtgacga acatcgaacc cggcactgtc gacaccgagt tgcgcgacca
    18061 catcgacgaa ccggccatca gcgccgccgt ccaggaggcc gtggcctcca tcgagggcct
    18121 tccctccggg agcgacatcg ccgagctgat cgccttcgcc gtcgagcgcc cgcgccacct
    18181 caacctgccc cagatctccg tgctgcccac acgggaagca tagtcagggg gacccccgca
    18241 ccccacggag tgccgacttc gaggggtgcc ccgccgctgc ggcgcgaacg cgcatacttc
    18301 ctcgccaact ggctgtcact ccggcaggca cgcggccact ccgtcgcttc cgccggtgct
    18361 gaaggcgttg atgcgctgct cggcgtcgcc gtggtcccgg gagttggtcc agggcgtgtc
    18421 gtcggccagc tccgtgagtg ccgcgcccag ctcgtccgag tcgccgtcct cgaactgcag
    18481 gtcggcggag ccgtagaggg ccgctcccgc cagacagtcg gcctggagtt cggcggcttc
    18541 gacggccagc ccgtccacgc ggttctgcac ggcgtgggcc cactcgtgag cgatcaccag
    18601 gtagatccac gcatcgccct tctcgtagcc cttgctcatc agcgcggcat cccatgcgat
    18661 gaagtcatcg gtcgtgcagt agaaggcgtt gtcgggtacg gccggctcgc caccacagct
    18721 cggggcctcg gctgtgccgg gtatatacgt gccgaacacc gtcggcgacg tgtaggcgcc
    18781 ggtgaagtgg tcattccaat gcgcgctcca gaagttgtcc accacggcga cggcgtcctc
    18841 ggcctcggat tcccagccct tgtccggtgt ctgcccacca tggggcgggt cgaccgcggc
    18901 ttttgtgggc tcgggcggct cgaacgactc cgttgtctcc gagccgtcct gagtgccttt
    18961 ccccagatcg ccctccgcgg agccgccgcc cccgcagcct cccgcgagga ggaccgcgga
    19021 ggcagtcaga gcaaggggcc aactgcggta tggcacacgt ggtttgcggg ccattttccg
    19081 gtctccgttc cccggcccgg gccatctgcc tccacccggc cagtctgctc gctgctttcg
    19141 gttcaaagag cgggattcag gtgaaggcga cggctgtcag agccgttgaa gccagcacgc
    19201 cgacggccgg ccaccacagc catcggcgac gaccgccggc gaaggcggcc acagtcagga
    19261 tctgggcgac caccgccacg gccgtggccg cggagagcag gagtgagcgg cgtcccgcct
    19321 gctcggcgag gtccacttga cggttctgtt cggcccgggc ggcccccagc ttcttcggct
    19381 ccctgctcag cgcggtgacc gtcgtcatgt cgacacggtc ttctgctacg ggaacccgcc
    19441 ccatgtactt cgcgatgctc cggatctgca ccgcgatggt gccttccacg gcggccatca
    19501 cacgttcgtg ccgggcgtcg gagggactga ttccggtgtc ccacacggcc agttcacgcg
    19561 cgagggcacc agcctccgca gccagggccg tccgcaggcc ctcagtcaga aaggcggtac
    19621 gcagaccgtg ggcctcgatg gaggcgctca gcctgacggc gctgcgagcg gcctcggcct
    19681 gggcccgctg ttcgccgccc gccgcgagta tctgccccag aggcagcagc agtggcagca
    19741 cgcaggccag gagattgaac agggcgctgc gccggtggcc cgccgaggcg gtggcgggct
    19801 gaggaatgat ctccagccgt ctgagcaccc tacggccgga tgccgtgggg gttcgttgcc
    19861 agcgccgcgg cctgaggaca ttggccgcgc acatggccac gagcacggcc agggttcctc
    19921 cggcggcgga ggccgtgccc caggcggccc accggtcgcc gtcgcgcatc tgggcgtccg
    19981 gggtcagccc gtacagcccg ggggagcgtt gttgcacatc cgccaggcgc tgcggcaggt
    20041 catagccgag atccttgtaa cggtaggccc cattgccgag caggtggtcg cgtctggccg
    20101 agcggggcag gtggaaggcg gtctgcgcgg ccagggtgta ctcggatgcc gcgagtctcc
    20161 cttcgttcct gatgggccgc agcccgtcgg cccgggcctc ggcggcggcc actctcatcg
    20221 cttgggggcc ctcatcggcg tagaccgcgc gaatgtcctc gaccatggcc gcctgccgcc
    20281 tgatctcctg tcgcatcgcg tcctggtagg caccggacga ctggctgaac tgccaggtgg
    20341 cgagcagggt cgcaccgacg atgatcgcga tgagggcgat ctggagccgg atgcgcaggc
    20401 tgaagcggga cggtcggccg gtcacagcga ctgcctgtcg taggcgattt gcgcgccctt
    20461 tacgtcggtg agcgtgagga cgtcgccgga gaccgaccag ccgtgacgct ctggagagcg
    20521 ttcggcgggc tggtcggtgt agtcacccgc agggtcgccg gggtcctgac gggacttggt
    20581 ggcagtcgtg gggttcagga agagccggtc gccctcgacg cgggccgtcc cctgggcgac
    20641 gaaagtgatc tggacgtcgt ctccgtccgt gttcggatag aagagcaggc cgacgtactt
    20701 gtaccgcccg tctgccgtga agcggtaggc gatggtgccc gagccaccgt cggggcggct
    20761 ctcccagact cccaccaggg tggccggcag cacagcttca cttgcctcgt tctgctgcgc
    20821 cgcggtggta gtcgccggtt ctgggaccga tggggtcacg ccgccgcttt ccggctcggg
    20881 agccgctgtg gtcgacgctc tactggaggt agcggtcgcg gagtcggccg ggtcggacga
    20941 ggagcaggcc acggcacctc tgaggagcag cacggcaacg agcgccccga ccggtccggg
    21001 catctggaag tgctctggca cggcgaagtc ccccgaatct tcatgctccg ctggtccagc
    21061 acatcgcaac gcacgtgcct gttcgggctc ccgtttccgg tgggctgggt gacgttgtca
    21121 agaggtcacg aaaagatctt cggtcgttct gtgaagagtt ccgcaacaga ctttatggat
    21181 tcgcgccccg tggcaccccg gggggcatcc ctagggtttt cgggcacgct accggacacc
    21241 tgcggggcgg ggctaccact cgcaaggaac acccatgtat cccgtaaagc gatcagtgaa
    21301 ggcacgtttc ttcagtgaaa gatatagacg ctcagtaagc gactgtcctt gaggtcttgc
    21361 agggtctagt cttggaatgc gttcaagggg agatcttcgg gggagttatg gccaatgatt
    21421 caggcggtgt gccggaggcg cagcagggca ccttcagtcg agcctggtca gagcatccgg
    21481 caacgatact ggccgctgtc atcggcgctc tcgcagtcct ggtagccgcc ctattcccac
    21541 tcctcaccgc ggaagactcc ggtggagatg gagcggccaa cgggtctggc cccacagccc
    21601 ccgtgccgcc ttctgactcc tccagcggac accagccgga accaacggtt gaccggacga
    21661 agtcatcggg gcctgagccg ccgatcaagt cgtcaccgcc ctcagcggcc aagccgcact
    21721 ggaaagggcc gatcaagatt ccggtaaacc tcaattccgt ttccgatacg ggagctgagc
    21781 tcgacagtga tgaaccggga agcctcgtgg gcgtcgacga tgacttgcgg ggggattact
    21841 ctacgactcc agcggtactg gtgatgactg gacgcgccgc ggaaataggt aagcccttag
    21901 ataagatcac caaagagatg tgcgagcaga ggactcccgt caaacccggc gacccgatgg
    21961 gaatcacggc ttaccgtacg ggaacgtatt gcttcgccac atccgaaggg agcatcgcgg
    22021 cattctcggt gacatctccg ccgagcatcc aagatattcc cagcgaactt acgatccagg
    22081 tggccctatg gaaatagtgg cgcctttact gatcgtttca gaatgcggtt cggaggcggc
    22141 ggaggcatat gaggctgcaa ggcagttcga gcaggccctg gtggaggtcg gcgcgtcgct
    22201 cgtagcgggt gcgggccgtg gcgcacgcct cctacgggcg ggggagcggt gccagttcgg
    22261 cgtgggtgac ggtgtagccg cccttgacga cgggggcgta cggggccggg gccatacagg
    22321 tgccgacctc ggcgtcctca ctgttcggca gcaggttcac cccgttccac gagaagccca
    22381 cccgatcggc cttgccgccc tttccgccgt cgtacacgct cagtccgacg cgcttgccga
    22441 gcgagccggt ctcctcgtgg ctgaccttcg tgatgagggc cgtgaccgtc gccgtgttcg
    22501 ggccggtgac caggcactcc acttggccct cggaggtata ggtgacgttc tggtcagccg
    22561 agtggtgcga gatgcgtacc gtcccccgcg cgtcgacggg cagccccgtg ggaatcttgg
    22621 gccgcgggat gctgtacggg gcggccaccg cgtcgaagct gaaggagcgt acatcgttgt
    22681 cgctcaggta cggcagtacg aagtccccgc tgccgacaat ccgcgccgcg cccggccggc
    22741 ggtggtccgt gcgctgctcg gcggacgagg cggtggacga ggtgcacagg gtgagcccgg
    22801 ccaccagggc cgcgatggta gcggtggcgg tgcgccgagc agacagtggc agcgaagcca
    22861 tgacgatctc cttttctgcg aaggggagtt gactggagga acgcgaccca tccttcgctt
    22921 tgacagccgc ccggtcgtca tctcaaggcc gcaagatcga tgccgcctaa tcgcccgcgc
    22981 ggctgaccag acgtcagccg agagtcgcac agggtggatc accgccggcc gcaggtgttc
    23041 gcggatcagt tgtcgcgctg gcgccgccca ggccccggct caagtgaggc actacgaaga
    23101 caccgtccgt aggaaggacg ggatcctgct gcacgccgac cggaccctgt ccttcgccgg
    23161 gcggctggtg agcggcgggc caccgttggc ccggcaccct cgtcacggtc tcgcgccagg
    23221 cagctgacgg acaccggagt cgtcggttcg gggcgctcca actggtcgct tcaggatgag
    23281 ttgcgtcgcg agtcttgcgc gcgacgatcg tggtcggaag ggtgtccggg atgcgtgctg
    23341 atcttgttcc tgacgacctg tgggagcagg tggccccgtt gctgccgcct cctcccgaac
    23401 ggcgccatcg ccaccctggg cggctgcgcg ttcccgaccg agtggcgctc gccggcgtca
    23461 tgtacgtgct gcggaccggt gtcgcgtggc gcgatgtccc cgcagagacc gtgggctgct
    23521 ccggcgtgac cgcctggcgc tggctgcggg actggaccga ggcaggcctc attctgaaac
    23581 gatcagttag acggtgtcct acgaggtcgt catgcgatcg tgcgcccggc gcgggaagtt
    23641 cgtggtgacc gcgcgaggga cgaggggaca tgctcaaggc cagaggggtc cccacactca
    23701 ccgtcggcat caagatgatc gggggcccac tgggcgaccc gcgatgtcgc ggtccggacc
    23761 gggaatgccc agggccaggt tgccgacatg gagcaacccg tcgtgatggc acttgaggaa
    23821 ggcgatctgg ttcgcggggc gcatggtgcc ggtggggcac gcgcccaggc cgaggtcggt
    23881 cgccgtgagg cacagcgtct gcaacaggca cccggcgtct cggtagatga ggctcagcgc
    23941 caggccctcg tacttccagc cggtgcgggc ggcgtgcgag gcgagcagga ggctcgcggg
    24001 cggcggatgc tccatgtagg ccggcatggt caccgtggtg ttcagtacgg ccgccagctc
    24061 gtcgtcccag ggggccagcc ggttcagggt gtggtcgaac gggtcgtagt ggtaggcgcc
    24121 gggagtcagc ccggagacct tccgggcgat cacgtacgtc tccacgctgt gccgtccgcc
    24181 gccggacgga gacggacgct gtgtctgctg gaacccgagg gggcccaagg ggccccggac
    24241 acgggccgag cgggcgagga acacagcgag gtggccgagg ggcagcggtg aggacgcgaa
    24301 gtcgcggatg ctgcgccgct cggtcagcac ctcgcgcagc gggcggctgg gcagctcatc
    24361 ggagtcggtg aggcggacgg tctctgtcga gtcggggtgc cgcaaccggg ccgggggcgg
    24421 ggagccttgc tgcgtgttcg cggcgggacc gtgtccggcc cgggcatgtg cggcgagttc
    24481 gtagggcgtc aacccttggg gcgcctggac ggtatgggcc gaggagcgga tgatcccggc
    24541 cgcggagagc tggtccaagg cccgctgggt cgccgcgagt tcggcctcgc cgttcccttc
    24601 gccgttcggg gcggacccgc cccatcgcgc gtggatctcc tcggtcgtga gcggccggtc
    24661 cagcgcgttg aggagcgcca gcagccgggg gcgggctgtg aacctgcgcc accggcggca
    24721 gtcgacgagg acgggccccg cctcgtcctg ccattccagg agcaggtcgg gactgcggcg
    24781 gtagtgcacg gggccggacg ggcttccgcc gtcggcaccg ctcccgcccg cgctgcgcgt
    24841 agggggtgcg ggggcttctg cggcacgggg cttcacggtt ctcgacgcct ctccgtaggt
    24901 cgtcacagga aggtctgtgg gccgtcacag gaagggcagc ggcagcggat tgagctgtgc
    24961 ctccgtcagc gctgtatcgc gtacgcccat ggcgagcggc gcctggaaca cccttggccc
    25021 gccgcggcgg tggaagtcgc tgcgcagagt gatcgggcac agtccgggca cgaccgttct
    25081 gacgaccgtc accccgcact cggccacgtc gatcggagtg atgtccacgg cgatcgcctc
    25141 gtgtcctcgc gccgcgagtc gccgcgtggc ctccgtgacg tcggcgggca gcccggggga
    25201 ggggcgccgg gccgcgacgg ggcgcagcgg cccctcgtcc cagaacgcca ggtgcgtgag
    25261 ccggtggggc gcccagtaga agagggagaa gtccttcagt gtggtcagca cctcgtccgg
    25321 ttcggggatc gtctcccccg cgtcgaggtt ctcctgccac agccgggcgc ccgcccagcc
    25381 caggcagccc tcttccaggg cgccgagcag ggccgcgtgc gggtccaggt cggcgcgcgc
    25441 ggagtgggtg accacgggcc gccgttcggt gtgccggagg aagcgcacgc cgaccaccgg
    25501 aattcccagg tcggtggtca ggtccttggc ggtgaccgtc acgccctggg cgcgcatgcg
    25561 ctcgacgatg cgccgggccg gaccttccgg cagcccgtcc aggtcgaggg tgggcaggac
    25621 gagccggttc tcccagaaga tcacggacgc gtccctctcg acggcctcca tcagaccgcc
    25681 gtgcaccgcg tggtggtaac tgccgcccgc cgcgaggccg gtggagatcg ggtcgtacca
    25741 ggcgcgatgg ccgggcggga agcggtaggg cagatagacg gcgcaggcgg ggacgtaccg
    25801 ggtgtggccg gtgagcaggg accggccagg cacccagtcg atctccgcgt ccgggtcgca
    25861 cggggccaag cgggtgtggc gggcgtactc cgccgccgaa cccaggggca gcgtgcgggg
    25921 atcgaccgcc tcgctgccca gggcggtggc ggaggcgcgc accaggctct ccgggtcgta
    25981 gacacccgcc gcataccgtt ccagggtctc gcccacggca cacacgcggg ccgtcaccgg
    26041 gtcgttcttg accgccccgc ctcgcgcctc ggccgtgacg ggcgagaacc agtgcgtctt
    26101 cgtcatcccg gccgtacggg cgtaggtcgc cttcccgatg gcctcgtcct gctcgtccac
    26161 cagcaggcgg agcaccattc cggtgagggt gtccaccgcg ccgcgcatcc gctcccaact
    26221 gagcgtgttg tcgatctccg tgggttcgtc ctcgcgccgg ggcggcacgg cgtgtgcggc
    26281 gcaggcgggg caccccggca ggtggaacag gtcgtgttcg gtgcgggcca gggagccgtg
    26341 ctcgatttcg gtcagtctca cgcggctctg cgtgatctcg tcttccggcg tctttccgct
    26401 ttccgccgcc tcgtcctctc cgtgccgggt tccggtaccc agcagggtga gcacttcgtg
    26461 ggcgagcagc ccggaggcga ccgccgtgct cggccatccg ccggagtccg acgcgccgaa
    26521 gaggacggtc aggggaagac cggcgatggg ctgccagatg tggttggcgc ggagccggcg
    26581 caccaggcac accggacagg gcgtgtgcgg cggccggaga gtggcgtgga agaaccgggt
    26641 cggggtatcg aggtaggtga ccaggggcgt cccggcttcc agcgcggaag cgacccggcg
    26701 caccagttgc tcctcgggga gcgagagcgg cagaaccgcg gcggccaccg gcgacgtccg
    26761 gtcatcggcc accgtcggca cgcccgcgcg ctccagcagc gcgctgacct cgccgcccaa
    26821 cccttggcgg gcgacggcga ccggtcggcc cgcgcggagc gcggtcatct ctccgtacaa
    26881 cgggtggacg gactgcccct gttgatgcgc gagcccgcgc gagcgcaggc cgcgcaccac
    26941 ccgttccgga acggcgtccg cccgcacggc ctcgctgccg gtcccgggag cgggcacccg
    27001 gacggggaca cgcagggttc cggtgctcgc gcagacgtag aggtggtcgc cgcgcgggac
    27061 caggcttacg tcgggacgca gctcggtggg ggcatgggca tccatggggc ggccttccgg
    27121 gagaggtgag gagacaacgc ccggttccgc gccgggccgg gcgcccgcga ccaggcgccg
    27181 cggtgcgcga agcgcccctg accgcctgtc acgcgcggtc aggggcgcgg ggcctcagga
    27241 gcctccggac gtgggagtca gcacgtccat ggagtgcggg gccgcccagg acagacagct
    27301 gtgtcccgcg aacgcctcct cggactccgg aatcgccatt tcctcgaaca acgcatctcc
    27361 gtcgatctcg acgggctgct ttgtctgctg cattatttcc gccctttcgc tcgcgtgtct
    27421 ctttcccttt tggttgagca ctccacagag aaaccgccac aggggcggtt tctctgttcc
    27481 attgcaagat gtcgagtgcg gcaatacaag agcatggtga aataacccac ccagcaggtg
    27541 atttggaggc ttccggggcg cgtgatgggg tggcacagaa cgcggcgcat ccgcccccga
    27601 gccacctggg aggcgcggaa ggctcggggg cctacgcgaa tgggccggtg gcccattcgt
    27661 caagggtcag cgcgaccggg agaccggggg gaccggcaaa caggtcaggc cggcgcgagc
    27721 agtccttcca gctccgcttc gaagaaggcc tccgcgtcga agcccatccc ggtgaagtgg
    27781 cccgccagtt cgagcgagag cacgccgtgc agtcgggtcc agaaggagag ggcgcggtgg
    27841 agctgggcgg gcgtggccgg gtgctcgccc gcccactgcc cgtgcgcctt gatgtggcgg
    27901 tcgaagggct ggtcgtcgac ctcggccgag gtgcgggccg ggagcttcgc gcaggcgtcg
    27961 agcagtgccg ccatgatctc ggacgcgatc ccggtgacgt cgtccggggc gtggtagccg
    28021 ggcacgggag tgccgaagac gaggaagtac cggtgggggt cggctcgcgc ccaccggcgc
    28081 atggcgtggg cgaggctcgc gaggtcggcg ccggaggccg tgccggtgcc gtcctcggcg
    28141 tcgccacgcc cgttgtcggc gtcggcgcgg aaggtgtcgg ccaagtcgcg gtaggcgtcc
    28201 cggatgagtt cggtgatcaa ctcgtcacgg ctgccgaagt agcggtagag cgccggtccg
    28261 ctcatcccca tccgcttggc gatcgcgttc agtgacagcg ccgaggcacc cgcgtcggcg
    28321 atctgctccc acgcccgctc tttgatctcg gcgcgtacct gcgtccggta ccgctcgcga
    28381 ggcgaaccgg cgccgggcgc ggtccgtgtc cccgcgcctt tccgccctgc cgtgcccgtc
    28441 ccgccggtct cggacatgcc gcctcacctg ttcttccctt gcccttagcc gcccgcatcc
    28501 ctgatgcctt gacgctggag ttagaggcta tcactcaatc ccttgacgac ttctttcgtt
    28561 agttatagct tctaactgaa gcggcaagcg ctagggaaag ttaggggccg taaaatggat
    28621 gctacggagc tggtcgaggt cgtgctgccg gggcgcgtcg agccggaggg gctggagttg
    28681 cggcgcggcc ccctgccgac cgcgggggcc ggacaggtgg tcgtcgagat ggaggcgatt
    28741 ggcgtctcct tcgccgagca gcagatgcgc cgaggccgct actacgacca gccgccgttc
    28801 ccgttcgtcc ccggctacga cctcgtcggt acggtgctgg cggccggccc cggtgccgcg
    28861 ccctcgctcg tcggcaagcg ggtcgccgcc ctgaccaaga ccggcggctg ggccagccac
    28921 gtcctgctgg acgcggcgga cgtcgtcgag gtgcccgggg gagtgggcgc cgcggaggcg
    28981 gagaccgcgg tggtgaacgg catcaccgcc tggcagatgc tgcaccgcaa ggcccgggtc
    29041 cgcgccggcc agacggtgct ggtgcacggg gcgaacggcg gggtcggctc gctcctggtc
    29101 cagctggccc tcgccgccgg cgcgcgcgtg atcggcacgg cgtccgcccg ccaccacgag
    29161 gcgctgcgac ggctcggcgt ccggacgatc gactaccgga ccgaggatgt gccgcgccgg
    29221 gtcggggagt tggccccggg aggtgtggac gcggtcttcg accatgtggg cgggcgcagc
    29281 gtcatcgact cgtgggggct gctcgctccc ggcggcacgc tcgtctcgta cggcaccgcg
    29341 gccacccgcg acgacaccgg gtccaagcag tggcccgtgc tcaagatcct cggccgggtg
    29401 tggctgtgga acggcctgcc caacgggcgt cacgcgtact tcttcaacgt ctgggcgggg
    29461 cgcgccttcg gcaaggaccg cttccgggcc cggctgcgcg ccgacctcgg cgaggtgttc
    29521 gccgcgctcg aacgcggtga gatcaccgcg agcgtcgccg ccgaactgcc cctggcccgc
    29581 gtcgccgacg ccatgaggct cgccgagtcc ggcacggtca gcggcaaggt cgtcctcacc
    29641 ccctgaccga caccggccgc cggcgggccc cacgcgcggc gaccggcgaa cacgcacccc
    29701 cagcggaccc atccacgcca caaggagaac cgaggcgatg accgacacca ataccgccgc
    29761 aggcgcaggc atcggtaccg gagcccacgc caagaccagt accgataccg gcgccgaccc
    29821 ccaccaactg ccctacctga caggccattt cgcccctgtc cccgacgagg tcaccgcatg
    29881 gggcctgacc gtccgaggtg ccctcccgcc cgagctgtcg ggccgctact tccgcaacgg
    29941 gcacaacccc ggacccggcc agaagcccac ccactggttc cgcggcgcgg gcatgctcca
    30001 cggtgtgcgt ctcggcgggg gccgcgccga gtggtaccgc aaccgctggg tccgcacccc
    30061 cgccctggag ggtgctccgc tggtccgcga cgacggcacc atggacctca ccgccggcgt
    30121 cgcgggcacc cacgtcatcg agcacgcggg ccgcatcctc gccctgcaag aggccaacct
    30181 gcccttcgag gtgggccccg agctcgacac gctcggcgcg tacgacttcc ggggcggact
    30241 cacgaccgcc atgacggcac accccaagga ggacccggag accggcgaac tgcacttctt
    30301 cggctactcg cccctcgcgc cgtacctgac gtactacgtc gccgacgcgc aaggggagtt
    30361 gataagaagc cgggtcgtgc ccggtgcggg ccccacgctg atgcacgact tcggcctcac
    30421 cgcgcaccac accgtctggc tcgacctgcc ggtcgtcttc gacgccgagg agcactccgg
    30481 gatcccgtac cgctggagcg acacgtaccg gccgcggatc ggcgtgatgc cgcgcgatgg
    30541 atccgccgag cccacctggt acgaggtgga ggccggcgcg atgatccatg tgaccaacgc
    30601 ctacgaggac gcggcgggaa ggatcgtcgt ggagggcccc cgctacgacc ggtcgtcctg
    30661 ggagagcagc tggaagtggt ggaccggcgc ccccggtcac ccgcccgtgc ccgtcgtcgg
    30721 ctcgatgcgg caccgctggg tcctggaccc ggccaccggg accgcccgtg aggagcggct
    30781 cgactccctc gtcaccgagt tcgccacgat caacgaggcg ttgaccggct cggcgcaccg
    30841 ctacacgtac accgtcgcct tccccggcgc gggtctggaa cggtacgcgc tggtcaagta
    30901 cgacgcgctg accgggcagc ggcagatcgc ggacgccggg cccgggcgga tgtacggcga
    30961 gccgtacttc gtaccggcgg ccgaggggac ggccgaggac gacggatacc tcatgaccct
    31021 cgtcagcgat ctcgcccggg acgcctccga actcctcatc ctgagcgcgc gggacatcac
    31081 ccggccaccg gtcgccgcgg tcgaactgcc gcgccgcgtc ccggcgggca tccacggctc
    31141 atggatcccc gacgcctgag ccgcgagccg cgcccgccgg gcctctccgc cgaagcgggc
    31201 cgaggcaccg gttcaccccc gggcgtcctt gctatcgccc tccgtgatgt cgtcctcgaa
    31261 gaggatcgcg tggacgcgtc gcagcacgtc gaggtgggcg cggttgtgga actcgagcag
    31321 cgcgtgcacg acgaccgact cggcgaccgc cgtttcccgg cgcgaggaga cccccaggtc
    31381 ggccaagccg gggtgatccc tgtgctgttg gcggacctca ggcgccatcc gctccgccag
    31441 tcgctgccgc acttcctcgg gagcgtcctc gtcgagcgcc gcgaagtccg cttccagagt
    31501 tccgcgaggg cccgagagct gttcccggag ggctgccatc gcctcgggtg tgaggatgct
    31561 ggagtaggcc agcagcaggg accgctgggc ctcgggcagg tcgtcggcga gcgtcctgaa
    31621 ctccgggggc atgtccagcg cggcccggtt ccccatgacg gccgccagtt cccgccgcat
    31681 ccgctgcttg cgtgcgatgt ccgccgcgag ttcgacgtcc aggtgcctaa ggatgcgcag
    31741 cgccttctcg tcgccactct cgaccagggg gacgtccgcg agggccacgc cgaggtcggt
    31801 cattctgcgg atgcgcagca ggcggaccag atggcttact ccgtactgct tgtagccgtt
    31861 gggcgctcgt tccggctctt ccagcaggcc gaggtcgtgg tagtgccgga cggtcttggt
    31921 cgtcgtgccc gcgagttccg ccagctgacg cgtactccac gccaccagaa gccctttctc
    31981 cagcatcggt cccggcgctc attcaaaacc gtgcccctgc ggcacggtca accaccgacg
    32041 ggttccccac cgaccggtgt tgaccatgcc cctggggcac ggagtgggat ggcctcgacc
    32101 acgaccccgg accggtatgc ggagactgga catgaaacga caaggcagtg tcggccagag
    32161 cctggccctc gtggcggttc tcggcctggg cggctcgccg gcccccgtgc ccgccgccgc
    32221 cgaggagccg aggacgccgc aggtggagtg gggccagtgc cccgacgacg tcgtggccga
    32281 agccgctccg accgcgttgc ggtgcgccac cgtgcccgta ccgctggact acgccgaccc
    32341 ggagggcgag cagatcgacc tcaccgtctc ccggctggcc gccgccgacc cggacaagag
    32401 gcgcggcgtc ctcatgctca acccgggcgg ccccggcggg tccggacttg cgctctccgc
    32461 gctgctggtg gcccatggcc tgcccagcag cgtcaccgag cgctacgacc tgatcggcat
    32521 ggacacccgc gggaccggtc attccacacc cgtcagctgc ggcttcacca cggacagccc
    32581 gtactactcc aacatcccgc cctacgcggt cgacgacgcc gcggtcaccg cgcaggcgaa
    32641 ggtcgccgag cgggcggccg agcagtgcgc ggacaacgac cacgacggcc gactgcgtca
    32701 cctcaccacc gcgaacaccg cccgcgacct ggaccggatc agggccgcgc tcggcgagga
    32761 gaagaccagc tacctgggtt actcctacgg caccgcactg ggcgccgcct acgcgtcgat
    32821 gttccccgag cacgccgacc ggatcgtgct cgacagcaac atcggggaca cccaccttga
    32881 ccgcgacggc ctgcgccgct acgcgctagg cacggcacag accctgccgc acttcgcgaa
    32941 gtgggccgcc cgccggcacg acagctacgg cctgggccgc acgccccacc aggtccgcgc
    33001 gtcctacctc accatcgccg gcaccctcga caaggcgccg gtcgcgggga tcgacggcgg
    33061 tctcttccgg cttctgacat tcggccacct gttcaaaaag acgcagtacc cccaactggc
    33121 acagacctgg caggcgatcc tcgaaggcga cgagacggcg ctccgcggcc tgccggccgc
    33181 ccaggaggaa gcggcggacg gggcgccgtc gccgaccgac aacgccctca ccgtatttct
    33241 ctccgtcacc tgcaacgacg tcgagtggcc cgaggacgtc aacacctacc ggcggggcgt
    33301 cgccgaggac cgcgaacgct acccgctgtt cggtgcggcc accgccaaca tcaccccgtg
    33361 cgccttctgg ccgcacgccc ccgccgaacc tccggtgaag atcggtaccg aaggtccgcg
    33421 gaacgtgctg ctcctgcaga accggcggga cgcgtcgacc ccgcaccggg gcgggaagat
    33481 gctgcgcgag aagttcggcg accgcgcccg gctggtcagc gtcgatgaca gcgggcacgg
    33541 cgtctacgtc ctgggcaaca actcctgcgc gctgaacacc accacgcgct acctcgtcga
    33601 gggcgagatg caggtgaagg acgtgttctg ccgcgcggac tgaccaccgg atccccacca
    33661 gtgctcacgc cgcccgtacg tcccgaaccc gatgttccgc gaaccggaag ggctcctcgc
    33721 ggtcaccgga ccgtcccgtt tgcctatagg gcataggtag atgcatgcta gccataggca
    33781 taccgagaga gggtgatggt tatggttcgg gcaggactga gcccggagcg gctgacgctc
    33841 gccggtgcgg aactcgccga tgaggccgga ttcggccagg tgactctgtc cgcgctcgcc
    33901 cggcgcttcg acgtgaagcc ggcgagcctg tacgcgcacg tgaagaactc ccacgatctc
    33961 aagacccgga tcgcgctgtt cgcgctggaa gagctcgccg accgggtcgc cgacgccgtg
    34021 gccgggcgcg cggggaagga cgccctgacg gccttcgcga acgcctaccg ggactacgcc
    34081 cgggcgcacc ccggccggta cgaagcagcc cgctaccggc tcgacccgca gaccgccgcg
    34141 gccagcgccg gcgtccggca cgcgcagatg acacgggcgc tcctgcgcgg ctacgacctg
    34201 gccgagccgg accagacgca cgcggtccgc atgctgggca gcgtcttcca cggctacgcc
    34261 tccctggagg cagccggtgg cttcgaccac acggacatcg ccgcgcagca gtcctgggcc
    34321 tggaccctgg actgcctcga caccgcattg cggagccggt ccgcctcctg accggtcgcg
    34381 tcacccgcga cgggttctca gtaaccggcc ctgcacacct ccaccccaca atgacaaggc
    34441 ttgaggcaat gagcaccgaa cagaagctga tcaccacccc catcaccgcc gacttcctgc
    34501 gcggccacct cgacgtcgaa gagactcccc acggcctgct gccgcaccgg ctgcccgccc
    34561 gggcgcgccg ccagatcccc gatgaccagc tggccgtggc cgaggcccag ccctccggtg
    34621 tccggctggc cttccgtacc agcgccacca cgatccgcct ggacaccctg ccgaccaaac
    34681 gcgtctaccg gggcttcccg cccccgccgg atggcgtcta cgacctcctg gtcgacggcc
    34741 gcctcaccgc ccaggccacc gtggacggcg ggaacctgcg caccatcacc gacatgcaga
    34801 cccagactgc cgaattcacc ccgggcccgg tcggcaccgc ccacttcacc gacctgcccg
    34861 ccggtgagaa ggacatcgag atctggctcc cccacgcgga gatcaccgag gtcgtcgccc
    34921 tgtacagcga cgcgcccgtc gagccggccc cgaagaccgg gcgccgggtg tggttgcacc
    34981 acggcagctc catcagccat ggatccaacg ccgtatcgcc cagcaccatc tggcccgcgc
    35041 tggccgcctc cgcaggcgat gtggagctga tcaacctcgg attcagcggc agcgcgctgg
    35101 tcgacccctt caccgcccgc gcgatgcgcg acacccgcgc agatctgatc agcctcaagc
    35161 tcggcatcaa cgtcgtcaac ggggacgcca tgcgcctgcg cgctttcgcc cccgccattc
    35221 acggcttcct cgacaccatc cgcgagggcc accccgcgat acccctgctc ctggtctccc
    35281 ccgtcctgtg tccgacccac gagaacaccc ccggacctct catgccggac ccctccggcg
    35341 gaaccctgaa gttcaaggcc accggcgatc cggccgagac cgccgcgggg cggctgacgc
    35401 tcacgatcgt ccgcgacgtc ctggccggca tcgtcgagca gcggtccgcc gaggacccga
    35461 acctccacta cctcgacgga ctcgacctct acggcgagag cgaccacgac gagttccccc
    35521 tgccggacgg gatccacccc ggccccgaag gacaccgccg catcggcgag aacttcgcca
    35581 agctcgtctt cgcagacaat gggcctttcg ccctcacgcc tggctgacat aggcgaccag
    35641 gactcggcca cacattccgg ggctacgcct cccgggcctt gtctgtcgat tcgggcctgt
    35701 cagcctcaca tccggaatca gacaggagct tttggagacg ccgcatcacg tcgacctggg
    35761 ccggattgta gagatcggca atggctttgc cgatggtgcg atcggcgtgc cgccggccac
    35821 gcggggcgtc cgaggcgagg tcgtgcagcc cgggatgctt gacctggaga cctcggacgt
    35881 aaggcacgag gcgctcggca aggctctggc gcgtctgctc gtccgcatcg gcgggaagtt
    35941 cgtcgagttc gcgtgccacc ggctgcggct gctcatggag caagtccgcg taggcgtcca
    36001 tgccgttggg gccgagaacc gtaccgagga cggtgacgaa agagcggtcg gggtcaggga
    36061 actctgctgt ctcgtccagg gaggcgaggc tgagagggag atcgctcgcg gccgttctgc
    36121 gcatgagggc gccgacctcc gcgcgggcgt gttgcagtcg ttcgatggtg gcggccaact
    36181 cgtcgtcgag agcccgcaga tcacgcgggt ccggggcgga atccgggccc tcccgcatgt
    36241 ccgcgatctg agagagggag aagcccaggg cggtgaggcg cttgatccgg aggagtcgga
    36301 cgaggtggct gacgccgtac tgcttgtatc cgttggagcg gcgctccggc tcgtcgagca
    36361 ggccgatgtc gtggtagtgc cgtacggccc tgaggctggt gccggccagc tccgccatct
    36421 cccgcgtgct ccacgccatg atcgatgtct ccctcaccgt ccggtgccct cggcgcgggc
    36481 gcgccaaggg cccattgaaa accatgacgc aacggcaggc cggcgcaggg gcggaacaga
    36541 acgacgggcc tctttcgcac ttcgcaaaaa tacaacagtg tcgcgaaatg tccatttcct
    36601 gggtttttaa aagtgtgccg taacgtcacc agtttcacgg atcgaaccag aggtagtagt
    36661 aacccagaaa gaaaaagcag cgtcagagaa ttcactcacc ggcgcatgtg gcagttgtaa
    36721 agacctgcct tctgtgtctt ctgtctccgt aaaggcgatt cgagaaaagc tgcgggatgg
    36781 agcgtgagcg aaaaatcctc ctgctgcgcg cgccatctct ttccgtgaac attccccgcc
    36841 ttgcaacggc cgacctacag ggaaaccact gtgcccacga ctctcgctca gaagctgtac
    36901 ctgctctgct acaccgtgga gaaggagaag ttccagctgg acaacattca gggacgcggc
    36961 cagctgctgc gggccggggc gatgaccgag ctggcccgtg agggtctgct ggacgccact
    37021 ggagggaagg ttcggcgact ccccggcaac ccgcccgagg atctgttcac cgccgcagtc
    37081 tggtgcgacc tgcccgagga caagc
//
