LOCUS       NZ_CP029617            26628 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7483385
            Orig. end                         :: 7510013
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26628
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26628
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26628
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16628](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16628
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(60..75)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            complement(139..1077)
                     /locus_tag="DMA15_RS33195"
                     /old_locus_tag="DMA15_33185"
     CDS             complement(139..1077)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="DMA15_RS33195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33185"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_125516376.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGAPATGTAANAYKGRLRVALAITITVMFAQIVGG
                     IMADSLALIADATHMATDALGLGMALLAIHFANRPPTENRTFGYARAEILAALANCLLL
                     LGVGGYVLYEAVERFITPADTQGGLAVFFGAFGLVANMISLSLLMRGQKESLNVRGAFL
                     EVVADTLGSVTVIVSATVIMLTGWQAADPIASLIIGVMIVPRTVKLLKETLNVLLESAP
                     KGVDMAEVRAHILALPGVEEVHDLHAWTITSGMPVLSAHVVVGSDTLDSIGHEKMLHEL
                     QGCLGDHFDVEHCTFQLEPSGHAEHEAKLCH"
     misc_feature    1171..1185
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(1201..1216)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.46"
                     /tool="antismash"
     misc_feature    1204..1219
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(1257..2240)
                     /gene="galE"
                     /locus_tag="DMA15_RS33200"
                     /old_locus_tag="DMA15_33190"
     CDS             complement(1257..2240)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-208). E-value:
                     8.3e-12. Score: 36.7. Matches aSDomain:
                     nrpspksdomains_DMA15_RS33200_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534459.1"
                     /locus_tag="DMA15_RS33200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33190"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_125516377.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-16, bitscore:
                     59.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-10,
                     bitscore: 38.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARVMAGAGEDVVVLDDISSGVPRRLPADI
                     PLIKGSALDGGLVRQVLAEHEVTGVVHLAARKQVGESVEQPSRYYRENVGGLTTLLEAV
                     AEAGVRRFVFSSSAAVYGNPPDVELVGEDTPCAPVSPYGETKLAGEWLVRAAGRAHGIA
                     TVCLRYFNVAGAAAPELADTGVFNVIPMVFDRLTRDEAPRIFGDTHPTPDGTCVRDYIH
                     VSDLAEAHLAAARRLAGGAEGDLTVNIGRGEGVSVRELIELIGEVSGDRRPALVEPARA
                     GDAPRAVADARLAADELGWTARRGVREMVESAWAGWCLHHPGAGRR"
     aSDomain        complement(1617..2048)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS33200_NAD_binding_4.1"
                     /evalue="8.30E-12"
                     /label="DMA15_RS33200_NAD_binding_4.1"
                     /locus_tag="DMA15_RS33200"
                     /protein_end="208"
                     /protein_start="64"
                     /score="36.7"
                     /tool="antismash"
                     /translation="HEVTGVVHLAARKQVGESVEQPSRYYRENVGGLTTLLEAVAEAGV
                     RRFVFSSSAAVYGNPPDVELVGEDTPCAPVSPYGETKLAGEWLVRAAGRAHGIATVCLR
                     YFNVAGAAAPELADTGVFNVIPMVFDRLTRDEAPRIFGDT"
     CDS_motif       complement(2169..2237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DMA15_RS33200_0001"
                     /evalue="2.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="DMA15_RS33200"
                     /protein_end="24"
                     /protein_start="1"
                     /score="16.8"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARVMAGAG"
     misc_feature    2460..2474
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     gene            2574..4385
                     /locus_tag="DMA15_RS33205"
                     /old_locus_tag="DMA15_33195"
     CDS             2574..4385
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="DMA15_RS33205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33195"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_125516378.1"
                     /transl_table=11
                     /translation="MSTAILTGQPVPGSPLEGDLRSLGFDVRGASDAADAETLLAAVPG
                     DQRVAVVDARFVGHVHALRLALTDPRFAASAVPGAVTAKPEARTALTRALRASASTGGV
                     LTLDALPDSIAAAMEAETSEDTVVHRPELGTLVATVPTDPQTRNEARQAVAAVDDEAVR
                     LRTAVKSRDGFFTTYAISPYSRYLARWCARRGLTPNQVTTASLLTALIAAGCAATGTRG
                     GFVAAGLLLILSFVLDCTDGQLARYSLRYSTLGAWLDATFDRAKEYAYYAGLALGAARG
                     GDDVWALALGAMVLQTCRHVVDFSFNEANHDATANTSPTAALSDKLDSVGWTVWVRRMI
                     VLPIGERWAMIAVLTAVTTPRLTLVVLLIGCALAACYTTAGRVLRSLTRKATRTDRAAT
                     ALADLADNGPLASAFAALRPRVTWLRPAPVLAFLGGAGLVGTALANPYGSPVVVAAAAL
                     YIALSGLALIMPLKAPLDWLVPPFFRAAEYGTVLVLAAKAEVNGALPAAFGLVAAVAYH
                     HYDTVYRIKGGTGAPPAWLVRAIGGQEGRALVVALAAALLSPADFTVALTALAVAVALV
                     VLVESIRFWVAAEKKGAPAVHDEGEPA"
     gene            4382..5119
                     /locus_tag="DMA15_RS33210"
                     /old_locus_tag="DMA15_33200"
     CDS             4382..5119
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="DMA15_RS33210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33200"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_125516379.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-10, bitscore:
                     40.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDTTILDLTLGNFAEI
                     GLTEVAIIVGYKKEAVYERKAALEAKYGLKLTLIDNDKAEEWNNAYSLWCGRDAIKHDV
                     ILANGDTVHPVSVEKTLLAARGNGQKIILALDTVKQLADEEMKVIVDADKGVQRITKLM
                     DPAEATGEYIGVTLIEGSAADELADALKTTFERDPDLYYEDGYQELVNRGFKVDVAPIG
                     DIKWVEIDNHDDLAKGREIACQY"
     gene            5107..6171
                     /locus_tag="DMA15_RS33215"
                     /old_locus_tag="DMA15_33205"
     CDS             5107..6171
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="DMA15_RS33215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33205"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_125516380.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.9e-21, bitscore: 75.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.2e-06, bitscore:
                     26.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALNDLAGVLADQRICSSTGKLAIAIS
                     GGSGAVLRDRLMPSLPGAEWFEVGGGTLDDAIKLADAMKKGRYDAVVGLGGGKIIDCAK
                     FAAARVGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPAR
                     FVRSGIGDALSNISAIRDWELAARERGEDIDGLAAAMARQAGEAVLRHPGGVGDDAFLQ
                     VLAEGLVLTGIAMSVSGDSRPASGACHEINHAFDLLHPKRAASHGEQCGLGAAFAMHLR
                     GAREESAYMASVLRRHGLPVLPEEIGFTVEEFVKVVEFAPQTRPGRYTILEHLDLSTDQ
                     IRDAYADYAKAIGS"
     gene            6149..6928
                     /locus_tag="DMA15_RS33220"
                     /old_locus_tag="DMA15_33210"
     CDS             6149..6928
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="DMA15_RS33220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33210"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_125516381.1"
                     /transl_table=11
                     /translation="MQKPSVAELRPVVHPPGVKDRRSGEHWAGRLYMREVSLRIDRHLV
                     NTRVTPNQLTYVMTVAGALAAPALLVPGITGAVLGVLAVQLYLLLDCVDGEIARWKKQY
                     SMAGVYLDRVAAYLCDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQTGKEPVKESASEPRSSGMALARRAAAALKFHRLILGVEASLLILVLAIVDQ
                     ARGDLFFSRVGVAVLAGIAMLQTLLHLVSILVSSRLK"
     gene            6946..7818
                     /locus_tag="DMA15_RS33225"
                     /old_locus_tag="DMA15_33215"
     CDS             6946..7818
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="DMA15_RS33225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33215"
                     /product="glycosyltransferase"
                     /protein_id="WP_125518168.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4.5e-11,
                     bitscore: 41.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVIITMGNRPQELRALLDSVAKQDGDPVEVVVVGNGAPVPE
                     VPEGVRTVELPENLGIPGGRNVGIEAFGPGGTDVDILLFLDDDGLLANTDTARLCREAF
                     AADPKLGIISFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTKVIAEVG
                     PLPGEFFYAHEETDLAWRALNAGWMIDYRSDMVLLHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWMLLTLARRPSRPALKAWFGGFKEGWTTPCGPRTPMKWRTVWRL
                     TRLGRPPVI"
     gene            7914..8852
                     /locus_tag="DMA15_RS33230"
                     /old_locus_tag="DMA15_33220"
     CDS             7914..8852
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="DMA15_RS33230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33220"
                     /product="ABC transporter permease"
                     /protein_id="WP_125516382.1"
                     /transl_table=11
                     /translation="MSETTHDGGVAVTASPSTPPPDDGLSRAELAAKYGLTVSGARPGL
                     FEYVRQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNALVYFLIFGLILEADR
                     GFEREVYIPFLVTGVFVFTFTQSSVMAGVRAISGNLGLVRALHFPRASLPVSFSLQQLQ
                     QLLFSMIVLFLITIGFGSYPRLSWLLIVPVLVLQFLFNTGLAMIMARLGSKTPDLAQLM
                     PFVMRTWMYASGVMFSIPVMLEDHPDWIADILQWNPAAIYMDLMRFALIDGYGSENLPP
                     HVWAVAGGWAVLLAVGGFVYFWKAEERYGRG"
     gene            8845..9654
                     /locus_tag="DMA15_RS33235"
                     /old_locus_tag="DMA15_33225"
     CDS             8845..9654
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568727.1"
                     /locus_tag="DMA15_RS33235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33225"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_206302889.1"
                     /transl_table=11
                     /translation="MADEKTPDLDKGGDASKAHIPTVIADELHIVYRVNGAKTGKGSAT
                     SALSRILRRGEERGVRKVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEK
                     GKVYTDGQPSLLGVNAALMNDLTGERNVILGGLAMGMSREQVKARYQEIVDFSGINEKG
                     DFITLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEARIRELRKEA
                     GTVFLVSHNNKSIRDTCDRVLWLERGELRMDGPTDEVIKEYEKFTGK"
     gene            10001..10900
                     /gene="hpnC"
                     /locus_tag="DMA15_RS33240"
                     /old_locus_tag="DMA15_33230"
     CDS             10001..10900
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639273.1"
                     /locus_tag="DMA15_RS33240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33230"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_125516383.1"
                     /sec_met_domain="phytoene_synt (E-value: 2e-38, bitscore:
                     130.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.5e-36,
                     bitscore: 123.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATDDLRLRDASAVLDKAAGENFPVAPFFLPRAWRDDLMAVYGVV
                     RLIDDIGDSDLAPEAAHARYLGLDPAHADDPPRLLDAVEADLGRLFDGGEPGHPLVRAL
                     RPTADRTAVTIDPFLGLIAANRQDQHVTRYETFDDLVAYCALSANPIGRLVLAITGTTT
                     PERLRLSDAVCTALQIVEHIQDVAEDLRRDRIYLPIEDMLRFHVSEADLAAPTAGASVR
                     ALVAYETERARCLLNEGTPLVGSVHGRLKLLLAGFVAGGRAAAQAIAAAGYDVLPGPPK
                     PTKPRLLREAGAVLRGEG"
     gene            10897..11847
                     /gene="hpnD"
                     /locus_tag="DMA15_RS33245"
                     /old_locus_tag="DMA15_33235"
     CDS             10897..11847
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="DMA15_RS33245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33235"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_164551879.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.1e-56, bitscore:
                     188.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.5e-68,
                     bitscore: 228.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRAVESDPQVSAPVLAAYSYCETVTGQQARNFAYGIRLLPAPKR
                     RAMSALYALSRRVDDIGDGALAPEVKADRLDETRQLLARIREGAVDEDDTDPVAVALAH
                     AAGHFPIPMEGLDELIDGVLMDVRGETYETWEDLKAYCRCVAGAIGRLSLGVFGTERGA
                     LDAERAPEYADTLGLALQLTNILRDVREDAVGGRTYLPAEDLAKFGCSAGFSGSTPPAG
                     SDFTGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIEREPEAVLR
                     GRVSLPGHEKAYVAVRGLSGLDARTVSRQTVRRRA"
     gene            11972..13381
                     /gene="hpnE"
                     /locus_tag="DMA15_RS33250"
                     /old_locus_tag="DMA15_33240"
     CDS             11972..13381
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058833.1"
                     /locus_tag="DMA15_RS33250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33240"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_125518170.1"
                     /sec_met_domain="DAO (E-value: 1.6e-10, bitscore: 39.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPDGLPADAGGRPGGAAAVVIGGGLAGITAALSLADAGLRVTLL
                     EGRPRLGGLAFSFRRGELTVDNGQHVYLRCCTAYRWFLDRVEGAHLAPLQERLDVPVLD
                     ADRNRLGRLRRAELPVPLHLASSLATYPHLSLAERAKVGRAALALKGLDPADPVLDGQD
                     FGSWLARHGQSPRAIEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSDPGAADIGWS
                     RVPLGELHDTLARKALDSAGVRTELRARVTSLSRTGDGGWRVQVPGETIEADTVVLAVP
                     QHEAHDLLPDGALDHPDRLLDIDNAPILNVHVVYDRKVLKRPFFAALGTPVQWVFDRTE
                     ASGLTDGQYLALSQSAARDEIDAPVAALRERYLPELERLLPAAHGAEVRDFFVTRERTA
                     TFAPTPGVGRLRPAARTKARGLYLAGAWTATGWPATMESAVRSGISAAEAALRALDRPR
                     DHLFAFEEATA"
     gene            13393..14523
                     /locus_tag="DMA15_RS33255"
                     /old_locus_tag="DMA15_33245"
     CDS             13393..14523
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983090.1"
                     /locus_tag="DMA15_RS33255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33245"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_125518171.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4e-58, bitscore:
                     195.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSGPQRTSTGTTSTGTRGETVPTVPSAETAADTVDVTSLLERGR
                     TLATPVLRAAVDRLASPMDTVAAYHFGWIDAAGNPSDGDGGKAVRPALALLSAEAAGAA
                     PEVGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANE
                     ILLEIGTVEAGRATRRLTTATRALIDGQAQDISYEHRERVTVEECLEMEGNKTGALLAC
                     AVSIGAVLGGADDRTADILEKYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKK
                     SLPVVAALAAGGPASERLGELLAADAKSSDFDTFSEEEFAARAALIEEAGGREWTAEEA
                     RRQHTIAIEALDTVEMPDRVRAQLVALADFVVVRKR"
     gene            14625..16628
                     /gene="shc"
                     /locus_tag="DMA15_RS33260"
                     /old_locus_tag="DMA15_33250"
     CDS             14625..16628
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639269.1"
                     /locus_tag="DMA15_RS33260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33250"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_125516385.1"
                     /sec_met_domain="T2TS (E-value: 1.5e-149, bitscore: 497.7,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAVTPRAASASQSTDTIAASAGARDAAARAIQRSTD
                     FLLSRQDAEGWWKGDLETNVTMDAEDLLLRQFLGIRDEHTTRAAALFIRGEQREDGTWA
                     TFFGGPGELSTTIEAYVALRLAGDRPDEPHMAKAAEWVRDRGGIAASRVFTRIWLALFG
                     WWNWDDLPELPPELIYFPSWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     TDAGEPNPARALAPVASWDGVFQRLDKALHVYHKVAPRRLRKAAMNSAARWIIERQEND
                     GCWGGIQPPAVYSIIALHLLGYDLEHPVLKAGLASLDRFAVRREDGARMIEACQSPVWD
                     TCLATIALADAGLPADHPQLVKAADWMLGEQVVRPGDWSVRRPGLTPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVAHPDKERVDNAIERGVRWTLGMQSRNGAWAAFDVDNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGMSHDPRTRRGIAWLLAEQEANGAWFGRWGV
                     NYVYGTGSVVPALIAAGLPAAHASIRRAVSWLESVQNDDGGWGEDLRSYRDRGWVGHGT
                     STASQTAWALLALLAAGEREAASVERGVTFLARTQREDGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVNGEPFADGPGHTSKGS"
     gene            16628..17281
                     /locus_tag="DMA15_RS33265"
                     /old_locus_tag="DMA15_33255"
     CDS             16628..17281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639268.1"
                     /locus_tag="DMA15_RS33265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33255"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_125516386.1"
                     /transl_table=11
                     /translation="MSEAPARRPGPAPLLIACALGIERLALRTGDRGGAPGAMTVLRTG
                     MGPENAERAVGGALGTEPLRDACVLATGFCAGLAPGMHPGDLVVAEETRDAHGSTLCTG
                     TELLVDELARALPGRTVHTGPLTGSDHVVRGPERGALLATGAIAVDMESAATLRSAVRA
                     GERPVAAVRVVVDAPQHELVRIGTVRGGISAFRVLRAVLPAFFEWHRSSLLPRR"
     gene            17287..18309
                     /gene="hpnH"
                     /locus_tag="DMA15_RS33270"
                     /old_locus_tag="DMA15_33260"
     CDS             17287..18309
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981497.1"
                     /locus_tag="DMA15_RS33270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33260"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_125516387.1"
                     /sec_met_domain="PF04055 (E-value: 2.9e-18, bitscore: 65.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.9e-09, bitscore: 34.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.5e-05, bitscore: 22.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLFEQKLRKRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKYVF
                     LCTNAMLLRKKLEKFTPSPYFAFAVHIDGMRERHDESVAKEGVFDEAVEAIKEAKKHGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLKVDEMMLSPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFSGGNRRRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESIRAARETVAGSRG
                     "
     gene            18337..20262
                     /gene="dxs"
                     /locus_tag="DMA15_RS33275"
                     /old_locus_tag="DMA15_33265"
     CDS             18337..20262
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010044657.1"
                     /locus_tag="DMA15_RS33275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33265"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_125516388.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.3e-110,
                     bitscore: 365.9, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-05, bitscore:
                     23.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILDTIRGPRDLKALTGAELDELSEEIREFLVHAVARTGGHLGP
                     NLGVVELSVALHRVFASPVDRIVWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SVHDIVENSHASTALGWADGLAKARQVLGERGHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYERVLAWGKDILQHTPVVGKPLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHDIGAVESALRRAKRFHGPVLIHCLTEK
                     GRGFEPALADEADRFHTVGAMDPLTCEPLAPAGGPSWTSVFGDEIVRIGAEREDVVAIT
                     AAMLGPVGLKKFAETYPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDLSVLQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLVRFPKEAVGPAIPAVDRVGGMDVLLRDDEPDVLLVAVGVMAPVCLQA
                     AELLRARGLRCTVVDPRWVKPVDDELPGLAARHRVVAVVEDNSRAAGVGSAVALALGDA
                     EVDVPVRRFGIPEQFLAHAKRSEVLADLGLTPVEIAGRIGATLAVKESVGEQGAGARGP
                     GKEYSV"
     gene            20259..21644
                     /locus_tag="DMA15_RS33280"
                     /old_locus_tag="DMA15_33270"
     CDS             20259..21644
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 1.5e-90.
                     Score: 295.6. Matches aSDomain:
                     nrpspksdomains_DMA15_RS33280_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="DMA15_RS33280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33270"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_125516389.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.1e-88, bitscore:
                     295.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEFDLGRLLAERGAERYELHARHLNHQLPRMLHTIGFDKVYER
                     AEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDASLADLTRFDCQPLPGL
                     LAERLLSHSPHLDRVFFGNSGTEAVETALKFARYATGKPRVLYCAHAFHGLTTGSLSVN
                     GESGFRDGFAPLLPDTAVPLGDLDALREELRHGDVAALIVEPVQGKGVHAAPPGYLRAA
                     QELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAKALSGGYVPVGATLGK
                     DWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDEKVVENARVTGELLKTRLA
                     ALVDRYELLSEVRGRGLMVGIEFGRPKSLKLRGRWSMLQAARKGLFAQMVVVPLLQKHR
                     ILTQVSGDHLEVIKLIPPLTVGEREVDRFVEAFIAVMDEAHSGGGLMWDFGKTLVKQAV
                     GNR"
     aSDomain        20382..21347
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS33280_Aminotran_3.1"
                     /evalue="1.50E-90"
                     /label="DMA15_RS33280_Aminotran_3.1"
                     /locus_tag="DMA15_RS33280"
                     /protein_end="363"
                     /protein_start="41"
                     /score="295.6"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAERLLSHSPHLDRVFFGNSGTEAVETALKFARYATGKPRV
                     LYCAHAFHGLTTGSLSVNGESGFRDGFAPLLPDTAVPLGDLDALREELRHGDVAALIVE
                     PVQGKGVHAAPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDE
                     KVVENARVTGELLKTRLAALVDRYELLSEVRGRGLMVGIEF"
     misc_feature    21692..21712
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.71"
                     /tool="antismash"
     gene            21718..22362
                     /locus_tag="DMA15_RS33285"
                     /old_locus_tag="DMA15_33275"
     CDS             21718..22362
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999178.1"
                     /locus_tag="DMA15_RS33285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33275"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_125516390.1"
                     /transl_table=11
                     /translation="MSPAESAESPPEPSEAGPAEALPAVAPQLRELRRRASLTLEAAAR
                     TAGLSPAHLSRLETGQRQPSLPMLLALARVYGTTVSELLGETVADRDAVVRGADMEPTR
                     AGGWTYWQAGAPGRGMQALRVHVPYGAQGDIVRVHPGEEWLYVIGGRLRLRLGDTAHLL
                     APGDSAHFDSLTPHRIAAADRGGADLLFVHTLLQSPATALCLGGPTQGEPT"
     gene            22416..22532
                     /locus_tag="DMA15_RS33290"
                     /old_locus_tag="DMA15_33280"
     CDS             22416..22532
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329167.1"
                     /locus_tag="DMA15_RS33290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33280"
                     /product="DUF6126 family protein"
                     /protein_id="WP_125518172.1"
                     /transl_table=11
                     /translation="MEEKFPRALWVRLIIYVAVGHIFAAFVYLLFELGAQNK"
     gene            complement(22557..23363)
                     /locus_tag="DMA15_RS33295"
                     /old_locus_tag="DMA15_33285"
     CDS             complement(22557..23363)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="DMA15_RS33295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33285"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_125516391.1"
                     /transl_table=11
                     /translation="MTQQAPPPELSEPELAGVRNFRDVGGLPTVDGRRVRPGRLFRSGH
                     LAHATASDTAFLTSLGLHTIFDFRNAADQRLEGPDVALPGVRNVNLPLTDPADGAEFWK
                     MVRDGDLDQLRAILSDGKAAGRMAASYRTIIKERTAEHSRVLHALAEGSVPALMHCAAG
                     KDRAGLSIAVTLLAVDVERDAIEADYLASNAAHRRYKVRRTSDSPNAMSPEVMELLNPL
                     FDARAEYLAAAFETIEETWGDTDTYLAEGLKVTPETRERLRERLLD"
     gene            23587..24393
                     /locus_tag="DMA15_RS33300"
                     /old_locus_tag="DMA15_33290"
     CDS             23587..24393
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308864.1"
                     /locus_tag="DMA15_RS33300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33290"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_125516392.1"
                     /transl_table=11
                     /translation="MRAESTTFVNHPYNNGVFNSYAAVGDSFTEGVGDPGPDGTFVGWA
                     DRLAVLLDDRVPEHTFRYANLAVRGKLLDQIVADQVPRAKELAPDLVTFCAGGNDIIRP
                     GTDPDEVAERFERAVADLTSAVGTVMVTTGFDTRGVAVLRRLRGKIATYNMHVRAIADR
                     YGCPVLDLWSLKTVQDRRAWDGDRLHLSAEGHTRVALRAAQVLGLEVPADPDQAWPPLP
                     PRGTLDLRRDDVHWAREYLVPWIGRRIRGESSGDHVAAKRPDLLPL"
     gene            complement(24398..25084)
                     /locus_tag="DMA15_RS33305"
                     /old_locus_tag="DMA15_33295"
     CDS             complement(24398..25084)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037677.4"
                     /locus_tag="DMA15_RS33305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33295"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_164551880.1"
                     /transl_table=11
                     /translation="MTQPTSADDQPGFRRARSPEHKAQRRQAILDAARGLATERGVRAV
                     TLGDIAREVGLTKSNVLRYFETREAIYLHLSAAGYRDWAARVQQAVRAGQPEPLAPARL
                     AGLLADSLDADPLFCDLLSDTAATLEHNVSLDAVRTYKEASTSAVHTLTAALTGPHTGL
                     GAEAAQDLILATALLTASTWTATHPSATLIELYRASPELGALAADFAPELARLLTLVVR
                     GLRAPA"
     misc_feature    25132..25146
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    25133..25149
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.96"
                     /tool="antismash"
     misc_feature    25138..25149
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            25185..26219
                     /locus_tag="DMA15_RS33310"
                     /old_locus_tag="DMA15_33300"
     CDS             25185..26219
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018835088.1"
                     /locus_tag="DMA15_RS33310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_33300"
                     /product="aldo/keto reductase"
                     /protein_id="WP_125516394.1"
                     /transl_table=11
                     /translation="MRMRELGRTGIKVSPYALGTMMFGAWGNPDHGESIRIIHKALDAG
                     INLVDTADVYSGGESEEIVGKALKGRRDDIVLATKVGNASPSATGPNTSGGSRRWIVRA
                     VEDSLRRLGTDYIDLYQIHRLDPSTDIEETLSALTDLLRSGKVRAIGTSTFPAAQLVEA
                     QWIAEHRALARFRTEQLPYSIIARGAERDVLPLTERYGMGVLVWSPLGSGLLTGRYRKG
                     HQPTGGRVAMERARFTHERKLDAVEKLIPLAEEAGVSLTHMAMAFVVGHPAVSSALLGP
                     RTMEQLDDLLAGADTVLGDDVLDRIDEIVPPGVTLDPHDLYFDPPALRDPALRRRTPDT
                     RSAA"
     misc_feature    complement(26301..26317)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.57"
                     /tool="antismash"
ORIGIN
        1 gcagccggcg ggtggtgtcg tcggagccgg ggccctgccg cggcaggccg tggtgcaggg
       61 cgaagaaggc gtcagcgacg gaggaggagt tgtcggtcaa cgtgggaaac ctttgggtcg
      121 gaagtgggag tgaaccgttc agtggcagag cttcgcctcg tgctccgcgt gcccgctcgg
      181 ttccagctgg aacgtgcagt gctccacgtc gaagtggtcg ccgaggcagc cctggagctc
      241 gtgcagcatc ttctcgtggc cgatcgagtc gagggtgtcg gagcccacga cgacgtgggc
      301 ggagagcacg ggcatgcccg aggtgatcgt ccaggcgtgc aggtcgtgga cctcctcgac
      361 gcccggcagg gcgagtatgt gggcccgcac ctccgccatg tcaacgccct tgggggccga
      421 ctccagcagg acgttcaggg tctccttcag gagtttgacc gtacgcggca cgatcatgac
      481 gccgatgatg agcgaggcga tcgggtccgc ggcctgccag ccggtgagca tgatcacggt
      541 cgccgagacg atgaccgtca ccgagcccag ggtgtccgcc accacctcca ggaacgcgcc
      601 ccgcacattg aggctctcct tctggccgcg catcagcagc gacagcgaga tcatgttcgc
      661 gaccagaccg aaggcgccga agaagacggc gaggccgccc tgggtgtcgg cgggggtgat
      721 gaaccgctcg acggcttcgt agaggacgta gccgcccacg ccgagcagca gcaggcagtt
      781 ggcgagcgcc gcgagtatct cggcgcgggc gtaaccgaag gtgcggttct cggtgggcgg
      841 cctgttcgcg aagtggatgg cgagcagggc catgccgagc cccagcgcgt ccgtcgccat
      901 gtgcgtcgcg tccgcgatga gcgccagcga atccgccatg atgccgccca cgatctgggc
      961 gaacatcacg gtgatcgtga tggcgagcgc cacccggagc cgccccttgt aggcgttggc
     1021 cgccgtaccc gtggccggtg ccccgtgcgt gtgtccgtga tcgtgcccag cccccatgga
     1081 gcccgcctcc cgcgtcggtc gtcgttctgc tgttcggtcg tcgcgcgacc acagtgaact
     1141 acgggtgggg ggtacctggc aacgcggcac tgaacaccgt tgtcatctgc tctgacctgc
     1201 gaaaatggca atgattgccg actggggaag cggtgcaggt cagcgcctcg cgacgatcac
     1261 cgacgccccg cgccggggtg gtgcagacac catcccgccc acgccgactc gaccatctcg
     1321 cgcaccccgc gccgcgccgt ccagcccagc tcgtcggcgg ccagccgagc gtcggccacg
     1381 gcacgcggcg cgtcaccggc gcgcgcgggc tcgacgagcg ccgggcggcg gtcaccgctc
     1441 acctcgccga tcagctcgat cagttcgcgc acggaaacac cctccccccg gccgatgttc
     1501 accgtcagat cgccctcggc gccgcccgcg agccgccggg ccgccgccag gtgtgcctcc
     1561 gcgaggtcgg acacgtggat gtagtcgcgt acgcaggtgc cgtccggagt ggggtgggtg
     1621 tcgccgaaga tgcggggcgc ctcgtcgcgg gtgaggcggt cgaagaccat cgggatcacg
     1681 ttgaagacgc cggtgtccgc cagctcgggg gccgcggcgc ccgccacgtt gaagtagcgc
     1741 aggcacaccg tcgcgatgcc gtgcgcccgc ccggccgccc gcaccagcca ctccccggcg
     1801 agcttcgtct cgccgtaggg gctgaccggc gcgcagggag tgtcctcccc gacgagctcc
     1861 acatcgggcg ggttgccgta caccgcggcc gacgacgaga acacgaaccg ccgcacgccc
     1921 gcctcggcca ccgcttcgag cagtgtcgtc aggccgccca cgttctcccg gtagtagcgc
     1981 gacggctgct ccaccgactc gccgacctgc ttgcgcgccg cgaggtggac cacgcccgtg
     2041 acctcgtgct cggcgaggac ctggcgcacc aggccgccgt cgagagcgga gcccttgatg
     2101 aggggtatgt ccgcgggcag ccgccgcggc actcccgagg agatgtcgtc cagtacgacg
     2161 acgtcctccc cggcgccggc catgacccgc gccacatgtg ccccgatata tccggccccg
     2221 ccggtgatca gccatgtcat gggcgcccac cctaagggcc cgcgccgcaa ctccctaagc
     2281 gagcgctatg cgggcaagcc gggcacgaga cgggcgcggt ttggaggggc ggccccccat
     2341 ccaccatgat gatcgtgaag gccgaggccc tcgcaggccg ccctgagagc ctgtgtcatc
     2401 accccggccg gggtacgaca aaggctctat cggggcgtga acgggtggtg aacgcccgct
     2461 tctcatcatc cgatagcctc tgccgacgtg ccgcccggcc gccatggcca ggggcgcccc
     2521 ccttacgcac gtgcccggcg cgagccgcgc cgggaatcaa ggagtgagtt cgtctgtcga
     2581 ccgccatcct caccggtcag ccggtccccg ggtcgccgct cgaaggtgat ctgcggtccc
     2641 tcggcttcga cgtgcggggc gcctccgacg cggcggacgc cgagacgctg ctcgccgccg
     2701 taccgggcga ccagcgggtc gccgtcgtcg acgcgcgctt cgtcggtcac gtccacgccc
     2761 tgcgcctggc cctcaccgac ccccgcttcg ccgcctcggc ggtacccggc gccgtcaccg
     2821 ccaagccgga ggcccgcacg gccctgacgc gcgcgctgcg ggcgagcgcc tccaccggcg
     2881 gcgtcctcac cctcgacgcg ctcccggact ccatcgccgc cgccatggag gccgagacct
     2941 ccgaggacac ggtcgtgcac cgtcccgaac tcggcaccct cgtcgccacc gtccccaccg
     3001 acccccagac gcgcaacgaa gcgcggcagg ccgtcgccgc cgtcgacgac gaggccgtac
     3061 gcctgcgcac cgcggtcaag tcgcgggacg gcttcttcac gacgtacgcc atcagcccgt
     3121 actcccgcta cctcgcccgc tggtgcgccc gccggggcct gaccccgaac caggtcacca
     3181 ccgcctcgct gctcaccgcc ctgatcgcgg cgggctgcgc ggccaccggc acccgcggcg
     3241 ggttcgtcgc ggcgggcctg ctgctgatcc tctcgttcgt cctggactgc acggacgggc
     3301 agctcgcccg ctactccctg cggtactcga cgctcggcgc ctggctggac gccacgttcg
     3361 accgcgccaa ggagtacgcc tactacgcgg gcctcgcact cggcgcggcc cgcggtggcg
     3421 acgacgtatg ggcgctcgcg ctcggcgcga tggtgctcca gacctgccgg cacgtcgtcg
     3481 acttctcctt caacgaggcg aaccacgacg ccaccgccaa caccagcccc accgcggccc
     3541 tctccgacaa gctcgacagc gtcgggtgga cggtctgggt gcgccggatg atcgtgctgc
     3601 ccatcggtga gcgctgggcg atgatcgccg tgctcaccgc ggtcaccacc ccgcgcctca
     3661 ccctcgtcgt cctgctcatc ggctgcgcgc tcgccgcctg ctacaccacc gccggccgcg
     3721 tcctgcgctc gctgacccgc aaggccaccc gcaccgaccg cgccgcgacg gcgctggccg
     3781 acctcgccga caacggcccc ctggcctcgg cgttcgccgc cctccggccg cgggtgacct
     3841 ggctgcgccc cgccccggtg ctcgccttcc tcggcggcgc cgggctcgtc ggcacggcgc
     3901 tggccaaccc ctacggcagc cccgtggtcg tggccgccgc cgcgctgtac atcgccctgt
     3961 cgggcctcgc cctgatcatg cccctcaagg cccccctcga ctggctggtc ccgccgttct
     4021 tccgcgccgc cgaatacggc acggtcctgg tactggcggc caaagccgag gtgaacgggg
     4081 cgcttccggc ggctttcggg ctggtggccg cggtcgccta ccatcactac gacacggtgt
     4141 accgcatcaa gggcggcacc ggcgcgccgc cggcctggct ggtgcgcgcg atcggcggcc
     4201 aggagggcag ggccctcgtg gtcgccctgg ccgcggccct gctgtcaccc gcagatttca
     4261 ccgtcgcgct cacggcactc gccgtggccg tggcactcgt ggtgctcgtc gagagcatcc
     4321 gcttctgggt cgccgctgag aaaaagggcg cacccgccgt acacgatgaa ggagaacccg
     4381 catgatcggc ctcgtgctgg cggccggcgc cggacggcgt cttcgccctt acacggacac
     4441 gctgcccaag gccctggtgc ccgtcgacgg cgacaccacc atcctcgacc tgacgctcgg
     4501 caacttcgcc gagatcggtc tcaccgaggt cgcgatcatc gtcggctaca agaaggaggc
     4561 cgtctacgag cgcaaggcgg cgctcgaggc gaagtacggc ctcaagctga ccctgatcga
     4621 caacgacaag gccgaggagt ggaacaacgc ctactccctg tggtgcggcc gtgacgccat
     4681 caagcacgac gtgatcctcg ccaacggcga caccgtgcac ccggtctccg tcgagaagac
     4741 gctgcttgcc gcgcgcggca acggccagaa gatcatcctc gccctcgaca cggtgaagca
     4801 gctcgccgac gaggagatga aggtcatcgt cgacgccgac aagggcgtcc agcgcatcac
     4861 caagctcatg gacccggccg aggccaccgg tgagtacatc ggcgtcaccc tcatcgaggg
     4921 ctccgccgcc gacgagctgg ccgacgccct gaagaccacc ttcgagcgcg accccgacct
     4981 ctactacgag gacggctacc aggagctggt caaccgcggt ttcaaggtcg acgtggcccc
     5041 gatcggcgac atcaagtggg tcgagatcga caaccacgac gacctcgcca agggtcggga
     5101 gatcgcgtgc cagtactgac gaggctcatc ccctcgccgg tcgtcgtcga catccggccg
     5161 ggggcgctca acgacctggc cggtgtcctc gccgaccagc ggatctgctc gtcgaccggc
     5221 aagctcgcca tcgccatcag cggtggctcc ggcgcggtgc tgcgggaccg gctcatgccg
     5281 tcgctgcccg gcgccgagtg gttcgaggtg ggcggcggca ccctcgatga cgccatcaag
     5341 ctcgccgacg ccatgaagaa gggccgctac gacgcggtcg tgggcctcgg cggcggcaag
     5401 atcatcgact gcgccaagtt cgccgcggcg cgcgtcggcc tgccgctggt cgccgtcgcg
     5461 acgaacctgt cgcacgacgg cctctgctcg cccgtcgcga ccctcgacaa cgacgcgggc
     5521 cgcggctcgt atggcgtgcc caaccccatc gcggtcgtca tcgacctcga tgtgatccgt
     5581 gaggcacccg cgcgtttcgt gcgctcgggc atcggcgacg cgctctccaa catctcggcg
     5641 atccgggact gggagctggc cgcccgcgag cgcggcgagg acatagacgg cctggcggcc
     5701 gccatggccc gccaggcggg cgaggcggtg ctccgccacc ccgggggcgt cggcgacgac
     5761 gccttcctcc aggtcctcgc cgagggtctg gtcctcaccg gcatcgcgat gtccgtgtcg
     5821 ggcgactccc gcccggcgtc cggcgcctgc cacgagatca accacgcctt cgacctcctc
     5881 caccccaagc gcgccgccag ccacggcgag cagtgcggcc tcggcgcggc cttcgcgatg
     5941 cacctgcgcg gtgcccgcga ggagtcggcg tacatggcat cggtgctgcg ccgccacggc
     6001 ctgcccgtgc tgccggagga gatcggcttc accgtggagg agttcgtgaa ggtcgtggag
     6061 ttcgctccgc agacccgccc gggccgctac acgatcctgg aacacctcga cctgtccacc
     6121 gaccagatca gggacgcata cgccgactat gcaaaagcca tcggtagctg agctccgccc
     6181 ggttgttcac cccccggggg tgaaggaccg gcgcagcggc gaacactggg ccggccggct
     6241 ctacatgcgc gaggtctccc tgcgcatcga ccggcacctg gtgaacacgc gggtcacgcc
     6301 caaccagctg acctacgtga tgaccgtcgc cggcgccctc gccgccccgg ccctgctggt
     6361 gccggggatc acgggcgccg tgctcggcgt gctcgcggtc cagctctatc tgctgctcga
     6421 ctgcgtcgac ggcgagatcg cccgctggaa gaagcagtac tcgatggcgg gcgtctacct
     6481 cgaccgcgtc gccgcctacc tgtgcgacgc cgcggtcctg gtcggcttcg gcttgcgcgc
     6541 cgccgacctg tggggcaccg ggcgcatcga ctggctgtgg gccttcctcg gcaccctggc
     6601 cgccctcggc gcgatcctga tcaaggcgga gaccgacctc gtcggcgtcg cccgccacca
     6661 gacgggcaag gagccggtca aggagtcggc gtccgagccg cgctcctccg gcatggcgct
     6721 ggcccgcagg gcggccgccg cgctcaagtt ccaccggctg atcctcggcg tcgaggcgtc
     6781 cctgctgatc ctggtcctcg cgatcgtgga ccaggcccgg ggcgacctgt tcttctcgcg
     6841 cgtgggcgtc gcggtcctcg cgggcatcgc gatgctccag accctgctcc acctcgtgtc
     6901 catcctcgta tcgagcaggt tgaagtgaac accccggcac aagagctgaa ggtcggcgcc
     6961 gtcatcatca cgatgggcaa ccggccacag gagctgcgcg ccctcctcga ctcggtcgcc
     7021 aagcaggacg gcgacccggt cgaggtggtc gtggtcggca acggcgcccc cgtccccgag
     7081 gtccccgaag gcgtacgcac cgtcgaactc cccgagaacc tcggcatccc cggcggccgc
     7141 aacgtcggca tcgaggcgtt cgggcccggc ggcaccgacg tcgacatcct gctcttcctc
     7201 gacgacgacg gcctgctcgc gaacacggac acggcgcggc tgtgccgcga ggccttcgcc
     7261 gccgacccga agctgggcat catcagcttc cgcatcgccg acccggacac cggcgagacc
     7321 cagcggcgcc acgtgccgcg gctgcgggcc tccgacccga tgcgctcttc gcgcgtgacc
     7381 acgttcctcg gcggcgccaa cgccgtccgt acgaaggtca tcgccgaggt cggcccgctg
     7441 cccggcgagt tcttctacgc gcacgaggag accgacctcg cctggcgcgc gctgaacgcc
     7501 ggctggatga tcgactaccg gtccgacatg gtgctcctgc accccacgac cgccccctcc
     7561 cggcacgcgg tctaccaccg catggtggcc cgcaaccgcg tctggctcgc ccggcgcaac
     7621 ctccccgcgc tcctcgtccc ggtctacctg ggcgtctgga tgctcctcac cctcgcccgg
     7681 cgcccttcgc gaccggccct gaaggcgtgg ttcggcggct tcaaggaggg ctggaccacc
     7741 ccgtgcggcc cgcgcactcc catgaagtgg cgtacggtgt ggcggctgac gcgactgggc
     7801 cgccctcctg tcatctgaca acctcggatc tgagagcatc tgggccatac cccggtccct
     7861 ggcccacgcc tacgcccgac cggctgcgca tctgaagacg aaagtttcca ctcgtgagtg
     7921 agacaacgca tgacggcgga gtcgcggtga cagcatcccc gtcgacaccg ccgcccgatg
     7981 acgggctctc ccgcgccgaa ctcgccgcca agtacggtct gaccgtcagc ggcgcacggc
     8041 ccggactttt cgagtacgtc cgccagctct ggggacggcg ccacttcatc ctcgccttct
     8101 cccaggccaa gctcaccgcc cagtacagcc aggccaagct cggccagctg tggcaggtgg
     8161 cgacgccgct cctgaacgcg ctcgtctact tcctgatctt cggcctgatc ctggaggccg
     8221 accggggctt cgagcgcgag gtctacatcc cgttcctggt cacgggtgtc ttcgtcttca
     8281 ccttcacgca gagctcggtg atggcgggcg tccgggcgat ctcgggcaac ctcggcctgg
     8341 tgcgcgcgct gcacttcccg cgcgcctcgc tgccggtctc cttctcgctc cagcagctcc
     8401 agcagctgct cttctcgatg atcgtgctgt tcctcatcac gatcggcttc ggcagctacc
     8461 ccaggctgtc gtggctgctg atcgtcccgg tcctggtgct ccagttcctc ttcaacaccg
     8521 gcctcgcgat gatcatggcg aggctcggca gcaagacccc cgacctcgcg cagctgatgc
     8581 ccttcgtgat gcgtacgtgg atgtacgcgt ccggcgtgat gttctccatc ccggtcatgc
     8641 tggaggacca ccccgactgg atcgcggaca tcctccagtg gaacccggcc gccatctaca
     8701 tggacctgat gcgcttcgcg ctcatcgacg gctacggctc cgagaacctg ccgccgcacg
     8761 tctgggcggt cgcgggcggc tgggccgtcc tgctcgccgt cggcggcttc gtgtatttct
     8821 ggaaggctga ggagcggtac ggccgtggct gatgagaaga cccccgacct cgacaagggc
     8881 ggcgacgcct ccaaggcgca catccccacc gtcatcgccg acgagctgca catcgtctac
     8941 cgcgtcaacg gcgcgaagac cggcaagggc agtgccacct ccgcgctgag ccgcatcctc
     9001 aggcgcggcg aggagcgcgg tgtgcgcaag gtgcacgccg tgcgcggcgt cagcttcacc
     9061 gcctaccgcg gcgaggccat cggcctgatc ggctcgaacg gctccggcaa gtcgacccta
     9121 ctgcgcgcca tcgcgggcct gctccccgcc gagaagggca aggtctacac cgacggccag
     9181 ccctcgctgc tcggcgtgaa cgcggccctg atgaacgacc tgacgggcga gcgcaacgtc
     9241 atcctcggcg ggctcgcgat gggcatgtcc cgcgagcagg tcaaggcgcg ctaccaggag
     9301 atcgtcgact tctccgggat caacgagaag ggtgacttca tcaccctgcc gatgcgcacg
     9361 tactcctccg gcatggcggc ccgcctgcgg ttctccatcg cggccgccaa ggaccacgac
     9421 gtcctgatga tcgacgaggc cctggccacc ggcgaccgca agttccagaa gcgctccgag
     9481 gcccgcatcc gcgagctgcg caaggaggcc ggcacggtct tcctcgtcag ccacaacaac
     9541 aagtccatcc gggacacctg cgaccgcgtg ctctggctgg agcgcggcga gctgcgcatg
     9601 gacgggccga ccgacgaggt catcaaggag tacgagaagt tcacgggcaa gtagcccgat
     9661 tgcgccatcg aggacccact cgttcgagga cagggccccg ccgggaggat tccggcgggg
     9721 ccctgccgtc cgtgcgggcc cgccgcgtcc cacccgtttc ccaacttccc ggcgcacggg
     9781 gaaggttgac gccaatcggt gtgttgttgt gatgtgccga acaccccgac gaagcgtgcg
     9841 gggttgtaca acgtaagctg taccggtgct gattcgcggc aagtcgggcg atatggagcg
     9901 atgccccggc cgggccacgg cccgcctcgg acagggccgg gcggcgtgtc cgaaatagga
     9961 tgtattgagt cggcagtgta gaacgggaga tgtgacggca atggctacgg atgatctccg
    10021 gctccgcgat gcatccgccg tcctcgacaa ggccgcgggc gagaacttcc ccgtggcccc
    10081 cttcttcctg ccccgcgcct ggcgcgacga cctcatggcc gtctacggcg tggtgcggct
    10141 catcgacgac atcggcgaca gcgacctcgc ccccgaggcc gcacacgccc gctatctcgg
    10201 cctcgacccg gcccacgccg acgacccgcc gcggctgctc gacgccgtcg aggccgacct
    10261 cggcaggctt ttcgacggcg gcgaacccgg acatccgctg gtgcgggccc tgcggcccac
    10321 cgccgaccgc acggccgtga cgatcgaccc cttcctcgga ctgatcgcgg ccaaccgcca
    10381 ggaccagcac gtcacgcgct acgagacctt cgacgacctc gtggcgtact gcgcgctctc
    10441 ggcgaacccc atcggccgcc tggtcctcgc catcaccggc accaccaccc ccgaacgcct
    10501 tcgcctctcc gacgccgtct gcaccgcact gcagatcgtc gagcacatcc aggacgtcgc
    10561 cgaggacctg cggcgcgacc gcatctacct gccgatcgag gacatgttgc gcttccacgt
    10621 cagcgaggcc gacctggccg cgcccacagc gggcgcatcg gtgcgcgcac tggtcgcata
    10681 cgaaacagaa cgcgcccggt gcctcctgaa tgaaggcacc cccctcgtgg gtagcgtcca
    10741 cggcaggctg aagctgctgc tggccggctt cgtggcagga gggagggcgg cggcccaggc
    10801 gatcgccgcc gccggatacg acgtacttcc cggtccaccc aagcccacca agccccgcct
    10861 gctgcgcgag gccggggcgg ttctgcgagg agaggggtga gccgggccgt ggagtcagat
    10921 ccgcaggtgt ccgcgccggt gctcgccgcg tacagctact gcgagaccgt caccggacag
    10981 caggcgcgca acttcgcgta cggcatccgg ctgctgccgg cacccaagcg gcgcgccatg
    11041 tccgcgctct acgccctctc ccggcgcgtg gacgacatcg gcgacggcgc gctcgcgccg
    11101 gaggtcaagg cggaccggct cgacgagacc cggcagctcc tcgcccggat ccgcgaggga
    11161 gcggtggacg aggacgacac cgacccggtg gccgtcgccc tcgcccacgc cgcggggcac
    11221 ttccccatcc cgatggaggg gctcgacgaa ctcatcgacg gcgtcctgat ggacgtacgc
    11281 ggtgagacgt acgagacatg ggaggacctg aaggcctact gccgctgtgt cgccggggcc
    11341 atcggacggc tctcgctcgg tgtgttcggt acggagcggg gggcgctcga cgccgagcgc
    11401 gcgccggagt atgccgacac actcggcctc gcgctccaac tgaccaacat tctccgggac
    11461 gttcgcgagg acgccgtggg cgggcggacc tatctgcccg ccgaggacct cgccaaattc
    11521 ggctgctccg ccgggttctc gggctccacg ccgcccgccg gatccgactt cacgggcctc
    11581 gtccacttcg aggtgcgccg cgcccgcgcc ctgttcgccg agggctaccg cctgctcccc
    11641 atgctggacc ggcgcagcgg cgcctgcgtc gcggccatgg cgggcatcta ccgccgcctc
    11701 ctcgaccgca tcgaacggga gccggaggcc gtcctgcgcg ggcgcgtctc gctgccgggc
    11761 cacgagaagg cgtacgtcgc cgtgcgcgga ctgtccggcc tcgacgcgcg gaccgtgtca
    11821 cggcagacgg tcaggaggcg cgcgtgaggt gcggcagagg aagccgggcg gcggctcagg
    11881 cggcccccgt gaagcggtgg gcaaccctcc gctccatggt cgcgtcccag actgcgacag
    11941 ccgaaaggga gggcgcgtga acagcgagga catgcggccc gacgggctgc ccgcggatgc
    12001 cggaggccgc cctggtgggg cggccgccgt agtgatcggc ggcgggctcg ccgggatcac
    12061 cgccgcgctc tcgctggccg acgcgggact gcgcgtgacg ctcctggagg ggcgaccgcg
    12121 cctcggcggc ctcgcgttct ccttccggcg cggcgagctg accgtcgaca acggccagca
    12181 cgtctacctg cgctgctgca ccgcctaccg gtggttcctc gaccgcgtcg agggcgcgca
    12241 cctggcgccc ttgcaggaac gtctcgacgt gcccgtgctc gacgccgacc gcaaccgcct
    12301 cggacggctg cgccgcgccg agctgcccgt gccgctgcat ctggcgtcga gcctcgccac
    12361 gtatccgcac ctctcgctcg ccgagcgcgc caaggtgggc cgcgcggcgc tcgccctcaa
    12421 ggggctcgac ccggccgacc ccgtcctcga cggccaggac ttcggcagct ggctggccag
    12481 gcacggccag tcaccgcgcg ccatcgaggc cctgtgggac ctggtgggcg tcgccaccct
    12541 caacgccgtc gcgggggacg cctcgctcgg gctcgccgcg atggtgttca agaccgggct
    12601 gctctccgac ccgggcgccg ccgacatcgg ctggtcccgg gtgccactcg gcgagctgca
    12661 cgacacgctg gcccgcaagg cgctcgactc cgcgggcgtg cgcaccgaac ttcgggcacg
    12721 cgtcacttcc ctctcccgta cgggcgacgg cggctggcgc gtgcaggtgc ccggcgagac
    12781 catcgaggcc gacaccgtcg tgctcgccgt gccgcagcac gaggcgcacg acctgctccc
    12841 cgacggcgcg ctcgaccacc ccgaccggct cctcgacatc gacaacgcgc cgatcctcaa
    12901 cgtccacgtc gtctacgaca ggaaggtgct gaagcggccg ttcttcgccg ccctcggcac
    12961 acccgtccag tgggtcttcg accggaccga ggcgtccggc ctcaccgatg ggcagtacct
    13021 cgcgctctcg cagtccgccg cgcgggacga gatcgacgcg cccgtcgccg cgctgcgcga
    13081 gcgctatctg ccggagctgg agcggctgct gcccgccgcg cacggcgcgg aggtacggga
    13141 cttcttcgtc acccgcgagc gcacggcgac cttcgccccc acccccggcg tcggcaggct
    13201 caggcccgcg gcccgcacca aggcccgcgg cctctacctc gcgggcgcgt ggaccgccac
    13261 cggctggccc gcgaccatgg agagcgccgt acgcagcggc atcagcgcgg ccgaggccgc
    13321 actccgcgca ctcgaccgcc cccgtgacca cctcttcgca ttcgaggagg cgacggcgtg
    13381 aagctcgacc tcctggggtc aggtccccag agaaccagca ccggaacaac cagcaccgga
    13441 acaagaggag aaactgtgcc gactgtgccc tcggccgaaa cggctgccga cacggtggac
    13501 gtgacctcac tgctcgagcg cggaaggacg ctggccaccc cggtgctgcg ggccgcggtg
    13561 gaccgtctcg cgtcgcccat ggacaccgtc gccgcctacc acttcgggtg gatcgacgcc
    13621 gcgggcaacc cgtccgacgg cgacggcggc aaggccgtgc gccccgcgct cgccctgctc
    13681 tccgccgagg ccgcgggcgc cgcccccgag gtcggcgtcc ccggcgcggt cgccgtcgaa
    13741 ctcgtgcaca acttctcgct cctccacgac gacctcatgg acggcgacga gcagcgccgc
    13801 caccgcgaca ccgtgtggaa ggtgcacggg cccgcgcagg ccatcctcgt cggcgacgcc
    13861 ctcttcgcgc tcgccaacga gatcctcctt gagatcggca ccgtcgaggc gggccgcgcc
    13921 acacgccggc tcaccaccgc cacccgcgcg ctcatcgacg gccaggcaca ggacatctcc
    13981 tacgagcacc gcgagcgggt caccgtcgag gagtgcctgg agatggaggg caacaagacc
    14041 ggcgccctgc tcgcctgcgc cgtctccatc ggcgccgtcc tcggcggcgc ggacgaccgc
    14101 accgccgaca tcctggagaa gtacggctac cacctcggcc tcgccttcca ggccgtcgac
    14161 gacctgctcg gcatctgggg cgacccggag gccaccggca agcagacgtg gagcgatctg
    14221 cgccagcgca agaagtcgct gcccgtcgtc gccgcgctcg ccgcgggcgg gcccgcctcc
    14281 gagcgcctcg gtgaactcct cgccgccgac gccaagagca gtgacttcga caccttctcc
    14341 gaggaggagt tcgccgcgcg cgccgccctg atcgaagagg ccggcggacg cgagtggacc
    14401 gccgaggagg cccggcgcca gcacaccatc gccatcgagg cgctggacac cgtcgagatg
    14461 ccggaccggg tgcgggcgca gctcgtcgcg ctcgccgact tcgtcgtcgt acggaagaga
    14521 tgatcactat cggccagata tgactcgcag tcgccggccg gcgcccagcg cgtcggccga
    14581 cggcggaccc agagcagagg aaccgactgc acgaagggga agccatgaca gcgacgaccg
    14641 acggaagcac cggagcggtg acgccccgcg cggcctcggc cagccagtcc accgacacga
    14701 tcgccgcgtc ggcgggcgca cgggacgccg ccgcgcgcgc catacagcgc tcgaccgact
    14761 tcctgctctc ccgtcaggac gccgagggct ggtggaaggg cgacctcgag accaatgtga
    14821 ccatggacgc cgaggacctc ctcctgcggc agttcctcgg catcagggac gagcacacca
    14881 cgcgcgccgc cgcgctcttc atccgcggtg agcagcgcga ggacggcacc tgggccacgt
    14941 tcttcggcgg ccccggcgaa ctctccacca ccatcgaggc gtacgtcgcg ctgcgcctgg
    15001 ccggtgaccg gcccgacgag ccgcacatgg ccaaggccgc cgagtgggtc agggaccggg
    15061 gcggcatcgc cgcgagccgc gtcttcaccc gcatctggct cgccctcttc ggctggtgga
    15121 actgggacga cctgcccgaa ctccccccgg aactcatcta cttcccctcg tgggtcccgc
    15181 tcaacatcta cgacttcggc tgctgggcca ggcagacgat agtgccgctc accatcgtct
    15241 ccgccaagcg gcccgtgcgc cccgcgccct tcgcgctgga cgagctgcac accgacgcgg
    15301 gcgagccgaa cccggccaga gcactggcgc ccgtggcgag ttgggacggc gtcttccagc
    15361 ggctcgacaa ggcgctgcac gtctaccaca aggtcgcgcc gagacggctg cgcaaggccg
    15421 cgatgaacag cgcggcccgc tggatcatcg aacggcagga gaacgacggc tgctggggcg
    15481 ggatccagcc gcccgcggtc tactcgatca tcgcgctgca cctgctcggc tacgaccttg
    15541 agcacccggt gctcaaggcc gggctcgcct cgctcgaccg gttcgccgtc cggcgcgagg
    15601 acggcgcccg gatgatcgag gcctgccagt cgcccgtgtg ggacacctgc ctcgcgacga
    15661 tcgccctcgc cgacgccgga ctccccgccg accacccgca gttggtcaag gccgccgact
    15721 ggatgctcgg cgagcaggtc gtgcggcccg gcgactggtc ggtgcgcagg cccggactga
    15781 ccccgggcgg ctgggcgttc gagttccaca acgacaacta ccccgacatc gacgacaccg
    15841 ccgaggtcgt cctcgcgctg cgccgggtcg cgcacccgga caaggagcgg gtggacaacg
    15901 ccatcgagcg cggggtgcgc tggaccctcg ggatgcagtc gaggaacggc gcctgggccg
    15961 ccttcgacgt cgacaacacc agccccttcc ccaaccggct gccgttctgc gacttcggcg
    16021 aggtcatcga cccgccgtcc gccgacgtca ccgggcacgt cgtggagatg ctcgccgtcg
    16081 agggcatgtc ccacgatccg cgcacccggc gcggcatcgc gtggctgctc gccgaacagg
    16141 aggcgaacgg tgcctggttc gggcgctggg gcgtcaacta cgtatacgga accgggtcgg
    16201 tggtgcccgc gctgatcgcg gccgggctgc ccgccgcgca cgcctcgatc cgccgcgccg
    16261 tgagctggct cgagtcggtg cagaacgacg acggcggctg gggcgaggac ctgcgctcct
    16321 accgcgaccg gggctgggtc ggacacggca cgtcgaccgc ctcgcagacc gcctgggcgc
    16381 tgctcgcgct gctggcggcg ggcgagcgcg aggccgcctc cgtggagcgg ggcgtgacgt
    16441 tcctcgcccg gacccagcgc gaggacggct cctgggacga gccgtacttc accgggaccg
    16501 gcttcccctg ggacttctcc atcaactacc acctctaccg gcaggtgttc ccgctcaccg
    16561 cgctcggcag gtacgtcaac ggcgaaccgt tcgcggacgg ccccggtcac acgtccaagg
    16621 ggagctgatg agcgaggccc cggcccgtcg gccgggcccc gcaccgctgc tgatcgcctg
    16681 cgcgctcggc atcgaacgcc tcgcgctgcg caccggcgac cgcggcggcg ccccgggagc
    16741 catgaccgtg ctgcgcaccg gcatggggcc cgagaatgcc gagcgggccg tcggcggggc
    16801 gctcggtacg gagccgctgc gggacgcgtg cgtcctcgcc accggtttct gcgcggggct
    16861 cgcccccggc atgcaccccg gtgacctcgt cgtcgccgag gagaccaggg acgcgcacgg
    16921 cagtaccttg tgcacgggca cggagctgct ggtcgatgag ctggcgcggg ccctgcccgg
    16981 gcgcaccgtg cacaccggtc cgctcaccgg ctccgaccac gtcgtgcgcg gccccgagcg
    17041 cggcgccctg ctggccaccg gggcgatcgc cgtggacatg gagtccgccg ccacgctgcg
    17101 cagcgcggta cgcgccggag agcggcccgt tgccgccgtc cgggtggtcg tggacgcccc
    17161 gcagcacgaa ctcgtccgca tcggcaccgt gcgcggtgga atatcagcgt tccgcgtcct
    17221 tcgtgccgtg cttcccgctt tcttcgaatg gcaccgttcc tctttgctcc cccggaggtg
    17281 agccagatgg ccatgccgct gcgccagacc atcaaggtcg ctacgtatct ctttgaacag
    17341 aagctccgca agcgtgacaa gttccccctg atcgtcgagt tggaaccgct cttcgcgtgc
    17401 aacctcaagt gcgagggatg cgggaagatc cagcacccgg ccggtgtgct caagcagcgc
    17461 atgccggtcg cccaggccgt gggcgccgtc ctggagtcgg gtgcgccgat ggtctccatc
    17521 gccggcggcg agccgctgat gcaccctcag atcgatgaga tcgtgcgtca gttggtggcc
    17581 aagaagaagt acgtcttcct ctgcaccaat gccatgctgc tgcgcaagaa gctggagaag
    17641 ttcacgccgt cgccgtactt cgcgttcgcc gtgcacatcg acggcatgcg ggagcggcac
    17701 gacgagtccg tcgcgaagga aggcgtgttc gacgaggcgg tggaggccat caaggaggcc
    17761 aagaagcacg gcttccgcgt caccaccaac tccacgttct tcaacaccga caccccgcag
    17821 acgatcatcg aggtgctgaa cttcctcaat gacgacctga aggtcgacga gatgatgctc
    17881 tcgcccgcct acgcctacga gaaggcgccc gaccaggagc acttcctggg cgtcgagcag
    17941 acccgggaac tcttcaggaa ggccttctcg ggcggcaacc gccgccgctg gcggctgaac
    18001 cactcgccgc tcttcctgga cttcctggag ggcaaggcgg acttcccgtg caccgcctgg
    18061 gcgattccga actactcgct cttcggctgg cagcgcccct gctacctgat gagcgacggc
    18121 tacgtcccga cgtaccggga actcatcgag gagaccgact gggacaagta cggccgcggc
    18181 aaggacccgc gctgcgccaa ctgcatggcg cactgcggct acgagccgac cgccgtcctc
    18241 gccaccatgg gatccctcaa ggagtccatc cgcgccgccc gcgagacggt cgcgggaagc
    18301 cgcggctgac cgacgaacca gagagggggc ccgagcatga ccattctcga caccattcgg
    18361 gggccgcgcg acctgaaggc actgaccggg gccgagctcg acgaactgtc cgaggagatc
    18421 cgggagttcc tggtgcacgc ggtcgccaga accggtggtc acctcgggcc caacctgggg
    18481 gtggtggaac tctccgtcgc cctgcaccgg gtcttcgcct cacccgtcga ccgcatcgtg
    18541 tgggacaccg gccaccagag ctacgtacac aagctgctga ccggacgtca ggacttctcc
    18601 aagctgcgcg gcaagggcgg cctgtcgggc tatccctcgc gggaggagtc cgtgcacgac
    18661 atcgtcgaga acagccacgc ctcgaccgcg ctcggctggg cggacgggct ggccaaggcg
    18721 cgccaggtgc tcggcgagcg gggccatgtg gtggccgtca tcggggacgg cgcgctgacc
    18781 gggggcatgg cgtgggaggc gctgaacaac atcgccgccg cgaaggaccg gccgctgatc
    18841 atcgtcgtca acgacaacga acggtcctac gccccgacca tcggcggcct cgccaaccac
    18901 ctcgccacgc tgcggaccac cgacggctac gaacgcgtgc tcgcctgggg caaggacata
    18961 ctccagcaca cccccgtcgt cggaaagccg ctctacgagt cgctgcacgg cgccaagaag
    19021 gggttcaagg acgccttcgc gccgcagggc atgttcgagg acctggggct caagtacgtg
    19081 gggccgatcg acggacacga catcggtgcc gtcgagtcgg ccctgcgccg ggcgaaacgc
    19141 ttccacgggc ccgtcctgat ccactgcctc accgagaagg gccggggctt tgagcccgcg
    19201 ctcgcggacg aggccgaccg cttccacacc gtcggcgcca tggacccgct cacctgcgag
    19261 cccctcgccc ccgcgggcgg gccctcctgg acctcggtgt tcggggacga gatcgtccgc
    19321 atcggcgccg agcgcgagga cgtcgtcgcc atcaccgccg ccatgctggg gccggtcggc
    19381 ctgaagaagt tcgccgagac ctacccggac cgcgtctggg acgtcggcat cgccgagcag
    19441 cacgcggcgg tatcggccgc cggactcgcc accggcggcc tccaccccgt cgtggccgtc
    19501 tacgccacct tcctcaaccg cgccttcgac cagctcctca tggatgtcgc gctgcaccgc
    19561 tgcggggtga cgttcgtgct ggaccgcgcc ggggtcaccg gcgtggacgg ggcctcgcac
    19621 aacggcatgt gggacctttc ggtcctccag gtcgtgccgg gtctgcggat cgccgcgcca
    19681 cgtgacgccg atcagctgcg cgcgcagctg cgggaggcgg tcgcggtgga cgacgcgccg
    19741 acgctcgtcc gcttccccaa ggaggcggtg gggcccgcga tccccgcggt ggaccgggtc
    19801 ggcggcatgg acgtactgct ccgggacgac gagcccgacg tactgctcgt ggcggtcggg
    19861 gtgatggcgc cggtctgtct tcaggccgcc gagctgctcc gggcgcgcgg gctgcgctgc
    19921 accgtcgtcg acccgcgctg ggtcaagccg gtcgacgacg agctgcccgg gctcgccgcg
    19981 cggcaccgcg tcgtggcggt cgtcgaggac aacagccgcg ccgccggggt cggctccgcc
    20041 gtcgcgctcg cgctcgggga cgccgaagtg gacgtaccgg taaggcggtt cggcattccg
    20101 gagcagttcc tcgcgcacgc caagcgcagc gaggtcctgg ccgacctcgg gctcacgccg
    20161 gtcgagatcg cgggaaggat cggggccacg ctggcggtga aggagagcgt gggggagcag
    20221 ggtgcggggg cgcggggtcc aggcaaggag tacagcgtat gaccaaggag ttcgacctcg
    20281 gcaggctgct cgccgagcgg ggcgccgagc ggtacgagct gcacgccagg cacctcaatc
    20341 accagctgcc gcgcatgctg cacaccatcg gcttcgacaa ggtctacgag cgggccgagg
    20401 gcgcgtactt ctgggacgcc gacggcaacg actacctcga catgctggcg ggcttcggcg
    20461 tgatggggct cggccggcac caccccgtcg tgcgcaaggc gctgcacgac gtcctcgacg
    20521 cctccctcgc cgacctcacc cgcttcgact gccagccgct gccgggcctg ctggccgagc
    20581 gactgctgag ccatagcccg cacttggacc gggtcttctt cggcaacagc ggcacggaag
    20641 ccgtcgagac cgcgctgaag ttcgcccggt acgcgacggg gaagccgcgc gtgctgtact
    20701 gcgcgcacgc cttccacggg ctgaccaccg ggtcgctctc cgtcaacggc gagagcggct
    20761 tccgggacgg cttcgccccg ctgctgcccg acaccgccgt gccgctgggc gatctggacg
    20821 cgctgcgcga ggagttgcgg cacggcgacg tcgccgcgct gatcgtcgag cccgtccagg
    20881 gcaagggcgt gcacgccgca ccgcccggat atctgcgcgc cgcacaggag ttgctgcacc
    20941 ggcacaaggc gctgctgatc gccgacgagg tgcagacggg cctcggcagg accggtgact
    21001 tctacgccta ccagcacgag gaaggcgtcg aaccggacct ggtctgcgtc gccaaggcgc
    21061 tgtcgggcgg ctatgtgccg gtcggcgcca ccctcggcaa ggactggatc ttcaagaagg
    21121 tctactcgtc gatggaccgc gtgctcgtcc actcggcgag cttcggctcc aacgcgcagg
    21181 ccatggcggc ggggctcgcc gtcctcgccg tcatggagga cgagaaggtc gtcgagaacg
    21241 cccgggtgac gggggagctg ctgaagaccc ggctcgccgc gctggtcgac cgctatgagc
    21301 tgctgagtga ggtgcgcggc cggggactca tggtcggcat cgagttcggg cggcccaagt
    21361 cgctgaagct gcgcgggcgt tggtcgatgc tccaggccgc ccgcaagggc ctcttcgcac
    21421 agatggtcgt cgtgccgctg ctgcagaagc accgcatcct cacccaggtc tccggcgatc
    21481 acctggaggt catcaagctg atcccgcctt tgacggtggg ggagcgggag gtggaccgtt
    21541 tcgtggaggc gttcatcgcg gtcatggacg aggcgcacag cggtggcggg ctgatgtggg
    21601 acttcggcaa gacgctggtg aagcaggcgg tcggcaaccg ctgaggcgtg ccttccgggt
    21661 ttttgcctct cgggcaagaa agttgcccga gaggcaaggc tctggctgaa tcggcgtatg
    21721 agccccgccg agtccgccga gtcgccgccc gagccaagcg aggcaggccc ggccgaagcc
    21781 ctgcccgccg tcgcgccgca attgcgcgag ctgcgccgcc gcgcctccct cacgctggag
    21841 gccgccgccc gcaccgcggg gctctcgccc gcccatctgt cccgcctgga gaccgggcag
    21901 cgccagccct cactgccgat gctgctcgcg ctcgcccgcg tctacggtac gacggtctcc
    21961 gagctgctcg gcgagacggt cgccgaccgg gacgcggtcg tgcggggcgc cgacatggag
    22021 ccgacccgcg cgggcggctg gacctactgg caggcgggcg ccccgggccg cggcatgcag
    22081 gcgctgcgcg tacacgtccc ctacggggcg cagggcgaca tcgtgcgcgt ccatcccggc
    22141 gaggagtggc tgtacgtcat cggcgggcgg ctgcggctgc gcctcgggga caccgcgcac
    22201 ctcctcgcgc cgggcgacag cgcgcacttc gactcgttga ccccgcaccg gatcgccgcc
    22261 gccgaccggg gcggcgccga cctcctcttc gtacacacct tgttgcagag ccccgccacc
    22321 gcgctgtgcc tcggtggccc cacccaggga gagccgacat gaccgagccc gagccgcagg
    22381 gaaccgcccg accggagcgg cccgccgaga acacgatgga ggagaagttc ccgcgggcgc
    22441 tctgggtccg gctgatcatc tatgtggcgg tcggccacat cttcgcggcc ttcgtctatc
    22501 tgctcttcga gctgggggcg cagaacaagt agggaccggt cgggccgcgt cccggctcag
    22561 tcgagaaggc gctcgcgcag ccgctcgcgg gtctcgggcg tcaccttgag gccctcggcg
    22621 aggtacgtgt ccgtgtcgcc ccaggtctcc tcgatcgtct cgaaggccgc cgccagatac
    22681 tcggcgcgcg cgtcgaagag ggggttgagc aactccatga cctcggggga catcgcgttc
    22741 ggcgagtcgc tggtgcggcg caccttgtag cggcggtgag ccgcgttcga cgccaggtag
    22801 tccgcctcga tggcgtcgcg ctcgacgtcc acggccagca gggtgacggc tatcgacagg
    22861 ccggcgcggt ccttgcccgc cgcgcagtgc atcagcgcgg gcacgctgcc ctcggcgagc
    22921 gcgtgcagca cccggctgtg ctcggccgtg cgctccttga tgatcgtgcg gtacgaggcc
    22981 gccatccggc cggcggcctt gccgtcggag aggatggcgc gcagctggtc gagatcgccg
    23041 tcgcggacca tcttccagaa ctcggcgccg tcggccggat cggtcagcgg caggttcacg
    23101 ttgcgcacgc cgggcagcgc cacgtcgggg ccttcgaggc gctggtcggc ggcgttgcgg
    23161 aagtcgaaga tcgtgtgcag gcccagcgag gtgaggaacg ccgtgtcgga cgcggtggcg
    23221 tgcgccaggt gaccgctgcg gaagagccgg ccggggcgga cccggcggcc gtcgacggtc
    23281 ggcagtccgc ccacgtcacg gaagttgcgc acgccggcca gctcgggctc tgacagctct
    23341 ggcggcgggg cttgctgcgt cacgggctct cctcggggct ctgctgccgg cgcggctcgc
    23401 cggtgaagac gccttcgacg atacgacacg ggttcggggg agcaatggcg ccctgcggcc
    23461 cacgtatttt ccgccacacg gcgtattccg gctttgggtg aatcttgacc ggtggcttat
    23521 ctcacgcccc gtcaacccct ccctacggtg gcgtaagtca cttagggagg tgaaggatgt
    23581 gactccgtga gagcagagtc gacaaccttc gtcaatcacc cctacaacaa cggcgtattc
    23641 aactcctacg cagcggtcgg cgacagcttc acggaaggcg tgggcgaccc gggccccgac
    23701 ggcacgttcg tcggctgggc ggatcgtctc gccgtcctgc tggacgaccg ggtacccgaa
    23761 cacaccttcc ggtacgccaa cctcgccgtg cgcggcaagc tcctcgacca gatcgtcgcg
    23821 gaccaggtgc cgcgcgccaa ggagctcgcc cccgacctcg tgacgttctg cgcgggcggc
    23881 aacgacatca tccgccccgg caccgacccc gacgaggtcg ccgagcgctt cgagcgggcc
    23941 gtcgccgacc tcacgtcggc cgtcggcacg gtcatggtga ccaccgggtt cgacacccgc
    24001 ggcgtcgccg tcctcaggcg tctgcgcggc aagatcgcca cgtacaacat gcatgtccgc
    24061 gcgatcgccg accgctacgg ctgcccggtg ctcgacctgt ggtccctcaa gacggtccag
    24121 gaccgccgcg cgtgggacgg cgaccggctg cacctctccg ccgagggcca cacccgcgtg
    24181 gcgctgcgcg ccgcccaggt cctcggcctc gaagtgcccg cggaccccga ccaggcgtgg
    24241 ccgccgctgc cgccgcgcgg cacgctcgac ttgcggcgcg acgacgtcca ctgggcgcgc
    24301 gagtacctgg tgccgtggat cggccggcgc atccggggcg agagctcggg cgaccatgtg
    24361 gcggcgaagc gcccggacct gctgccgctc tagcgcgtca ggccggtgcc cggagacctc
    24421 ggacgacgag ggtgaggaga cgggccagct cgggggcgaa gtcggccgcc agggcgccca
    24481 gttcggggga ggcgcggtac agctcgatga gggtggccga ggggtgcgtg gccgtccacg
    24541 tgctcgcggt gagcagcgcg gtggcgagga tgaggtcctg cgccgcttcg gcgcccaggc
    24601 ccgtgtgcgg gccggtgagg gcggcggtca gggtgtggac cgccgaggtg gacgcctctt
    24661 tgtaggtgcg cacggcgtcg agtgagacgt tgtgctccag cgtggccgcc gtgtcgctga
    24721 gcagatcgca gaagagcggg tcggcgtcga ggctgtccgc gaggaggccg gcgaggcggg
    24781 cgggggcgag tggttccggc tggccggctc gtaccgcctg ctggacgcgc gcggcccagt
    24841 cccggtagcc cgcggcggac aggtggagat agatcgcctc gcgggtctcg aagtagcgca
    24901 gcacgttcga cttggtcagg cccacctcgc gggcgatgtc cccgagggtg accgcgcgca
    24961 ccccgcgttc cgtggcgagg ccccgggcgg cgtcgaggat ggcctgccgg cgctgcgcct
    25021 tgtgttccgg actgcgtgcg cgtcggaagc ccggctgatc gtcggctgag gtcggctgcg
    25081 tcaccacatc gctcacccta ccaaccggtc accactcaaa agtacgctgt actcttaata
    25141 agagaacgcc gtacctttag tgatccgagc ggtaggagca gcacatgagg atgcgcgaac
    25201 tgggacggac cggcatcaag gtcagcccgt acgccctcgg cacgatgatg ttcggcgcct
    25261 ggggcaaccc cgaccacggc gaatccatcc ggatcatcca caaggcgctc gacgcgggca
    25321 tcaacctcgt cgacaccgcc gacgtgtact ccgggggcga gtccgaggag atcgtcggca
    25381 aggccctcaa ggggcggcgc gacgacatcg tgctcgccac caaggtgggc aacgccagtc
    25441 cctcggccac cggccccaac acctcgggcg gctcgcgccg ctggatcgtg cgcgcggtgg
    25501 aagactccct gcgccgcctg gggaccgact acatcgacct ctaccagatc caccgcctcg
    25561 acccctccac ggacatcgag gagaccctgt ccgccctcac cgacctgctg cgcagcggca
    25621 aggtgcgcgc gatcggcacc tccaccttcc ccgccgcgca gctcgtcgag gcgcagtgga
    25681 tcgcggagca ccgcgccctc gcgcgcttcc ggaccgagca gctgccgtac tcgatcatcg
    25741 cgcggggcgc cgagcgggac gtactgcccc tgacggagcg gtacggcatg ggcgtactgg
    25801 tgtggagccc gctcggcagc ggcctcctca ccggccgcta ccgcaagggg caccagccca
    25861 ccggcggccg cgtcgccatg gagcgcgccc gcttcaccca cgagcgcaaa ctcgacgccg
    25921 tggagaagct gatcccgctc gccgaggagg ccggcgtctc cctgacccac atggcgatgg
    25981 cgttcgtcgt cggccacccc gccgtctcct ccgcgctgct cggcccgcgc accatggagc
    26041 agctcgacga cctcctcgcc ggagcggaca ccgtcctcgg cgacgacgta ctggaccgca
    26101 tcgacgagat cgtgccaccg ggcgtcacgc tggaccccca cgacctctac ttcgacccgc
    26161 ccgcccttcg cgatcccgcc ctgcggcgcc gcacgccgga cacgcggtcc gcggcctgag
    26221 cgcgggcgcg ggagggcgcg cccgcgtgcg ccgccgcccg gacggcgtcg acataaacgg
    26281 cgtggacata ataggaaccc tgcccacctt ttcaggaggt cccgtgtccc ggtccttgat
    26341 ccccgggctc cgctcgctgc ggtcccccgc cttcggcgcg gacccggccg gcgcgcggct
    26401 ggcgcggatc cgcaggtcgc cgaacttctc cgtggccgac gggtccttcc agaaccccgt
    26461 aggcgcccgg accaggccct cgggatccac catggagctg gcgaagatct acttccgcaa
    26521 ggaggagcgc gtacgccgtg gccccgccgc cccgatcccg gtgcacgcca cgaccctcgc
    26581 ggacctcgcc aagccgccgg ccgacggact gcggatcacc tggatggg
//
