LOCUS       NZ_CP029617            22166 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6586658
            Orig. end                         :: 6608824
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22166
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22166
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22166
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12166](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12166
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(195..626)
                     /gene="grpE"
                     /locus_tag="DMA15_RS29330"
                     /old_locus_tag="DMA15_29320"
     CDS             complement(195..626)
                     /GO_function="GO:0000774 - adenyl-nucleotide exchange
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_function="GO:0051087 - protein-folding chaperone
                     binding [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="grpE"
                     /inference="COORDINATES: protein motif:HMM:NF013212.4"
                     /locus_tag="DMA15_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29320"
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="WP_125515732.1"
                     /transl_table=11
                     /translation="MSDPTARLAYEHARDLAARDAAHQALTERLLLRCADVLDSFDRLL
                     ADGAASDVEAYRRSLALIAGQLEAALTEEGLEPLGRVGERAEPATHQVTEVRAAPPGSA
                     DDEVLEILQRGYRYRGQVLRAARVVVAADGGTEQGTERE"
     gene            complement(619..999)
                     /locus_tag="DMA15_RS29335"
                     /old_locus_tag="DMA15_29325"
     CDS             complement(619..999)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_29325"
                     /product="hypothetical protein"
                     /protein_id="WP_125515733.1"
                     /transl_table=11
                     /translation="MIKDPDASWEGPFPYDALAPAGVTPWTTHAEMRDVSFELLARHLM
                     TPVTQQAWDELRGVRRRMLVDLLLYDVDPDAELPLAADEIDRRLAAETASQEQHVPSDE
                     QPERPLPEATARLLDDLIRFDV"
     gene            complement(996..6884)
                     /locus_tag="DMA15_RS38060"
                     /old_locus_tag="DMA15_29330"
     CDS             complement(996..6884)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="DMA15_RS38060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29330"
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_125515734.1"
                     /transl_table=11
                     /translation="MTAVLAYEELRIRVRRVGGDRYLVTANGPAAAAEIITVGEEPAVL
                     REQWDRLIAAELCLAPMGDQHTVAQLRELGRGVFRLLFGGEGAEPEEDAGGEAGAGGDD
                     EAREGGEGREEIGTRVGVCVDAAFDRAQGMSRQRGLRLRFDLPPELRDLPLESLCGPPG
                     SPQQAFALNHAYSLARSLPGGPLGQRLPDPADEPSVIRLLVACASPGDLPRLRTSAEVA
                     ALRHDLPDVAVKTTVLERASRANLASALAADPELPTAVVLIAHGEYDQELGKGVVSLET
                     RSGGVDRVPADVLSGILLKSRRLRLIALNLCFSADSSHLEPFSGLAQALIGGGVPAVVA
                     MRGLVSDVSAGAFSPELLKGIAANKTVDESVAAARLRISHQPEHTAVEWATPTLFLHEG
                     CRQGWLFKAREVRDRAEPDPLRQGADALRTFQSPFGHVASDVLIGAARFQRDRGLWAQV
                     QRILRTEGESYADEQRRLRTEAAFELAWHEVEKLCALLAEGRDASAAAAQWAVVRRELP
                     GAVPGCLAGEVAELERLAALVEEARTAEAAADWATAISRYEDVLAARPGGLRDVAERLA
                     AARDELHVARTCEAAERARRAGDWGAAARGYAAVLTLRPGHDTASAWAAYVAGRAAEAA
                     GDWSAAQTAYGACAGLEDAAGRAAYARGRAAAGGGDWPGAREAFAQAGAERGAWCAYAE
                     GRVAEAAGAWGAAVTAYGAADGFLDSGVRLLYARGRDAADAGRLVEAVTDLSAAATERD
                     VLGGRGPVAVPEQNGGGPRQQQGPAGAPEQDAGGAGQQLGPQGPVAVPEHGGSHQQPEA
                     PGPSVVHAYGGCDVEPYLGELRRQVYEAALAAVESGDWATASAHLAPLPAGYAATETLR
                     RYVAGRSAAVAGDWGAAVEAFGAVVRGGPQDGVPADAPRLRTYAEGRLCQEQGRWAQAL
                     AHFAGLPSELADVPDRVLYSRGRAADERGEWSGVIDGFGRLPDAYADGEVGVRRLYARA
                     RVAADSRADWTAVLSLLTGVPDEAREGAVGALRRKAEGRRAEEAGNWRGACEIYARAFP
                     PPPSGQAASPAPGAPLDEPTHLHLYALARTHELDGRWQDALGVYDALDGHWADVTARRR
                     YARARIAEEGAEGSAAWRHVVEAYEELEREEAHGVDAAARGRYARVRLAEAEGDWARAA
                     AEAGALGAHRDAPAVAAYARGRLADAHQEWQRAADAFRQCPGHRDADAHLAYAEGRLLE
                     AAGKWSAAVEAYGRARGVLDRADVRCRRMRRLVGLLPWADGLTSTPLVADPFAVQDRAF
                     PYLALRDAGVDPGASMDVVKNASYALLERGSLSWHERVALERLRLPARRLQLDALLYRW
                     HSPEALRDALAGLSPDEGPGLLDTLCERFPRDAPLLLLLARDREAAAAEWERRLREAPG
                     DMAVVHGLAAARLWQAQELEQSGAWEHAVGAWEAALAYWATLLSDDEYWDGWRAERAVC
                     YERDLTHDDMASLRWELSQHLFGQLSAYEQRHTEQDRPQQAAAYQALAGLLESELGGAR
                     VLKDVGGLPSVPGAGATLACGPRYLRLLRLQAPLGDLVASLDAAAQRGEDPGEYAVREL
                     RWAFSELARSFALCEVRKFGHALRALPVLRTLSTLPDDCAGPASEAGHTEGCGHCQDFL
                     RRNPAYVRLPRRHARLLQDGVELAVHVRLALARAALTRGDGGLDEALEHWRELVRVSRD
                     AGMQARSKKAVIRTVLGRVEALTDEEGAQLGPCLDEAVRLVESATAALHPLDRDLLGQL
                     NGKLSALLSLRGVWRGYTRTKHGMRCDVYGAEADLRRALALNPESSHARDNLARALVFT
                     LDERTYEVPARLELLHEALDLLDVGLGQALTHRYRETLGEALDEMEKLLTRHLGVGGMG
                     DLIRSDGQETPPDVDDLPSWAAELTDKAERALRGGEILWALHHLIRATRADPTDSRIRR
                     ALLDAVRRWLTELSPADGATENEAGGSVA"
     gene            complement(6881..9265)
                     /locus_tag="DMA15_RS29345"
                     /old_locus_tag="DMA15_29335"
     CDS             complement(6881..9265)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1272: TPR
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS29345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_29335"
                     /product="hypothetical protein"
                     /protein_id="WP_125515735.1"
                     /transl_table=11
                     /translation="MTAQTADTTDTTDTTATELLGAEQACADGESALKRGEHARAEEHF
                     RKALSLAGEGDGRGGAGGGEESFEGGGTENRVSPAEQGGDGSGGSRADGDGAGESQGGV
                     GLRGPGGKAVRVVARALTGVGRVRLAAGEVAEAVAEFERARRLRPTAAGPLHWLGCAAA
                     HQGDLAAAERHLTAALACPAPHPRSLVQRAYVHARAGAPDAALRDLRAASRIAPLDDEA
                     HWVMAALSGRPAREVALRLRRAALRGLMGVRRAARTDCNGSDDAEEKAGWERAGALVDA
                     ARTLDREPDGFAPLHAVVLVRGGRRAAAVELLGEAVRDDPADHRVTHTLALALLNSLGE
                     PSGSHWERCVAAWAAVLHDAGFWERARATAARRYDVAVEASLVPVLRAGLREALERRLP
                     DDAGTRVAPGALLQREADAAKLLAAAGGFPSAQGGGAPLVCGPLRIAELGRSAEFGAFA
                     AAQEARMLQAGAAFGAARQGQAFPADGVASQKAAHPAEGTQDALAAPASGTPPTYTSLT
                     YAFSELGFAQLMLGMGKPADALAALSELRCPGCRARGSGPGAAAVCEPECARFDELNPG
                     YAGLPDKHRRLSLDARGLALEARLSMGRVELVADRPDFAAAAAYWRRALVHSRQLDRYR
                     ETQTAIVDMALGAARAAHREGRLTRAVSTLEATRSVIGANERGRLEGQLARVLADRAIS
                     VANEEDALLDEPAADLRRSVAFNPHLLRAQVSLGIVLRRLAGARWASGSLSGARATLRE
                     AIDQLTAALTYFPDDPDLEEQREAAVTDLNHVMWQPDESEQ"
     gene            complement(9318..9788)
                     /locus_tag="DMA15_RS29350"
                     /old_locus_tag="DMA15_29340"
     CDS             complement(9318..9788)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642272.1"
                     /locus_tag="DMA15_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29340"
                     /product="hypothetical protein"
                     /protein_id="WP_125515736.1"
                     /transl_table=11
                     /translation="MTDAPPRAELLLDRDVPEDLGRELVAAFDRLGAPPVRVRRTLVHR
                     GAADIPWIVLASLPLQAFLSGLGAEAVKDAYAAFKGVVRRTARPASATDGGARPLVLQD
                     PAGGLSIVLEPDLPAEAYESLVALDLAKFTVGPLHYDRAQGRWRSVLDEAAG"
     misc_feature    9740..9754
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            10001..12166
                     /gene="cyc2"
                     /locus_tag="DMA15_RS29355"
                     /old_locus_tag="DMA15_29345"
     CDS             10001..12166
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133697.1"
                     /locus_tag="DMA15_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29345"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_125515737.1"
                     /sec_met_domain="T1TS (E-value: 1.4e-79, bitscore: 267.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPHFYMPYAARLNPHLEEARAHSSRWARDMGMLEGSGIW
                     EQSDLDAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLDMYKRTQDRAAGKAH
                     LDRLPLFMPMDLSTPVPEPRNPVEAGLADLWARTVPAMSADWRRRFAESTEHLLNESLW
                     ELSNINEGRVANPVEYIEMRRKVGGAPWSAGLIEYATAEVPAAVAGSRPLRVLMETFSD
                     GVHLRNDLFSYQREVQDEGELSNGVLVLETFFGCTTQQAADIVNDVLTSRLHQFEHTAV
                     TEVPALALEKGLTPAEVAAVAAYTRGLQDWQSGGHEWHLRSSRYMNEGALATSPLAGPT
                     GIGTSAADVGALLASAGAERLRAFTHIPFQKVGPSILPDFEMPFPLRLNPHLDAARPRL
                     TAWSHAMGILEEGVWDEDKLDAYDLPLCAAGIGPDGSAEALDLSSQWLAWGTYGDDYYP
                     LVFGHRRDFAAARLCTERLAGCMPIEGEPLTVPVNGMERGLADLWARTTRDMTPEQRRT
                     TRHTVVVMTESWLWELANQLQNRIPDPVDYLEMRRATFGSELTMSLCRMGHGPAVPPEV
                     YRSGPVRSLENAAMDYAMLLNDVFSYQKEIEYEGEVHNGILVVQNFFGCDYPTGLKVIH
                     DLMTQRMRQFQHVAEHEFPVLYEDFGLSAEARAVMDGYVTELQNWLAGILNWHAGCRRY
                     GAEDLARRAHGFLPDRAPRVPSIAGLR"
     gene            complement(12219..12980)
                     /locus_tag="DMA15_RS29360"
                     /old_locus_tag="DMA15_29350"
     CDS             complement(12219..12980)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642269.1"
                     /locus_tag="DMA15_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29350"
                     /product="hypothetical protein"
                     /protein_id="WP_240659998.1"
                     /transl_table=11
                     /translation="MTTDTAMTGAEAGRHAHHSPTARVALIGERSPNVTSHNRMPLLLD
                     ALAAHDRLVLDAYWVATDDAEDPDAVRGFDAVWVLPGSPYRSEAGALTAIRTAREEGIP
                     FLGTCGGFQHTLLEYARHVCGLSDVAHAENDPGADDLLIEPLACSLVGHEGTVTLAPGS
                     LAESLLGADRSVERYHCSYGPGPHLDTLRAHGLRFTGEDEEGRVRIAELPGHPFFLATL
                     FQPELFGDGSRPHPVIRGLARAAVRHARVPA"
     gene            13076..13945
                     /locus_tag="DMA15_RS29365"
                     /old_locus_tag="DMA15_29355"
     CDS             13076..13945
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642268.1"
                     /locus_tag="DMA15_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29355"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_125515738.1"
                     /transl_table=11
                     /translation="MDPHLLRTYVTVARLASFSEAARALGYTQSAVSQHIAALEQDLGS
                     ALLTRRPVAPTPAGARLLEHAGPLLLRLDAARAEVVRMASAPEHGLTLAATPTALTRRT
                     AEALPPAGVTLSVLPRDEIPAAVATGAVDLGLVDGLAAPNDPLRLPDVAPLTARGTGQE
                     PVAVLLPEGHPLARRTGLRLGDLVHARWIDAPGTGLPLAQLRAANGTSGFRPALRYDGT
                     DLRTLAALAAAGHGLTLLPRSAAAGVPGTVAVPLTAPRVVHRTELLHAGTLRGAAAALA
                     AHLDVTRS"
     gene            14112..14708
                     /locus_tag="DMA15_RS29370"
                     /old_locus_tag="DMA15_29360"
     CDS             14112..14708
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657043.1"
                     /locus_tag="DMA15_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29360"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_346428928.1"
                     /transl_table=11
                     /translation="MPAVLSGLLLAVLLVLAGIGIGVGAVGATVLDVSGLAGTGEAASP
                     TGAPRPTAGGPESEAPKPEASKPALKSAPPKSAPPKSEAPKPGPPKPAPPKSPQAGPAS
                     AAKPARTSTLGVEAVDAPGGAGALLVGVHLPGPGHSAGLVHGDTLLAFGGTRVGSAAAL
                     ASAVAAAPPGTQVTLTVRHKNGARQTLAVRPGIVT"
     gene            complement(14732..15745)
                     /locus_tag="DMA15_RS29375"
                     /old_locus_tag="DMA15_29365"
     CDS             complement(14732..15745)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378528.1"
                     /locus_tag="DMA15_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29365"
                     /product="aldo/keto reductase"
                     /protein_id="WP_125515740.1"
                     /transl_table=11
                     /translation="MKQRFLGRTGLRVSELCFGAMMFGSGADETTSHRMLDAFTEAGGT
                     FVDTADMYGRGVSEEVLGRWLKGRRRDELVIATKVFSTMGESPNAGGLSRKHILSAVDA
                     SLRRLGTDYIDLYQTHVWDATTPIEETLSTLDTLVKAGKVRYLGASNHSPAQLQKALDV
                     ARARCWEPYSCLQPLYNLLARESEWELLPLSAAEGVGVIPYSPLQGGWLSGKFRRSMAA
                     PPEGARGSGAWRERNTEETWRVVDALLEVADEAGRTPSQVALRWLLQRPGVTAPIVGAR
                     SVEQLADNLGCVDWELTSEQQERLTSASARPLPYPYDVLAYYPGREPRSGPRTDFG"
     gene            complement(15810..17555)
                     /gene="treZ"
                     /locus_tag="DMA15_RS29380"
                     /old_locus_tag="DMA15_29370"
     CDS             complement(15810..17555)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="DMA15_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29370"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_125515741.1"
                     /sec_met_domain="CBM_48 (E-value: 5.6e-05, bitscore: 22.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 2.9e-11, bitscore:
                     42.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFEVWAPQAERVALECAGATRAMERDAGRAGWWTAEAEAEDGTR
                     YGFSVDGGPVLPDPRSRRQPDGPDGLSAVVDHDRYAWRTPWAGRGVREAVLYELHVGTY
                     TREGTLDAAADRLRHLADLGVTHVELMPLCPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDAAHGLGLGVVLDVVHNHLGPSGNYLPAFGPYFTETHHTPWGAAVNLDAPGSDEVR
                     AYLVGSALAWLRDYRLDGLRLDAVHALRDTRACHFLEELSAAVDSLSDDLGRPLSLIGE
                     SDLGDPRVVTPRARGGLGLHAQWNDDFHHALHTALTGEAQGYYEDFARAPLAALGKTMT
                     RGFFHDGTYSTFRGRAHGRPVDRARTPAHRFLGYAQTHDQIGNRAQGDRLSASLSPGLL
                     ACAAALTLMGPFTPMLFMGEEWGATTPWQFFTDHTDPELAEAVRRGRRREFAAHGWAEE
                     DIPDPQDPAARERSCLDWSQPETGHHARVLAWHRELISLRRARADLMDPDLAAVRVAFD
                     ERARWFAFRRGDLKIAVNLAGEAAAVPLGHNHARVLAAWEPVEPPGADGLLRLPAESCA
                     VLGPA"
     misc_feature    17581..17596
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            17699..18250
                     /locus_tag="DMA15_RS29385"
                     /old_locus_tag="DMA15_29375"
     CDS             17699..18250
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385491.1"
                     /locus_tag="DMA15_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29375"
                     /product="DUF1707 and FHA domain-containing protein"
                     /protein_id="WP_125515742.1"
                     /transl_table=11
                     /translation="MTSSFEFSTYPARVTDAERDRALDALKEGAAVGRLSHDTFLRRME
                     LVLAARRPDELAALTADLRTEGRWSRMVLGSVEAVSGFTMKLRRAWQAERLPKLLLPSP
                     DSPYPLRIGRDPANGLRLSHDTVSRVHAELRRQGGVWVLRDLGSTNGTSVNGRRVTGSA
                     LVQDGDLVSFGRMAFRLAVS"
     gene            complement(18298..19578)
                     /locus_tag="DMA15_RS29390"
                     /old_locus_tag="DMA15_29380"
     CDS             complement(18298..19578)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643570.1"
                     /locus_tag="DMA15_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_29380"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_240660287.1"
                     /transl_table=11
                     /translation="MAAVADQAGVSQLAVQRYPTVPELITSARQLAAHRPELSTLRQIG
                     ASRAGRPLHLLSVGHASRAVLVVAGAHANEPIGGSTLLHLAERALRDPRLRADTSWHFL
                     LCADPDGASLHRTPAPRTLLDYHRHFFRPAGPEQPEWSPSVLPPHRLPPETRALTAVID
                     ELRPYLQVSLHCTDLGGSWVQLTEDIPGLAEPFAKSAAELHIPVETGASDAAGWPVSGP
                     GVHVLPAAGAQAAYPSLPEDARLTTWHHAHRYGGRTAIVEVPMWASDLVDDPAAHPAPG
                     PAMRAFARRLRRDGRLVEEVLAEALPRLPGEEGPLLRAARWALALVPGLADDWARLPPA
                     STTVAYIGSVDAFGRRLPLRAAAMLLRVLTEADDRAAPRLDRLVTRWSEALAERFGARW
                     VPLEHQIEHQSRTTVAAARHARACGGE"
     misc_feature    complement(20454..20470)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    21008..21017
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(21309..21323)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(21745..21758)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.22"
                     /tool="antismash"
ORIGIN
        1 gggctgcctg accgcccagt tcagcgcgtc ctcgccgacc agcggctggt ccttgccgtc
       61 gcggctcttg acgccgacga ccgacggggt gagccgctcg cccttgctgt tggtgagcac
      121 cgcgatgtcc gcgcggtgcg gatcgtgggc ggcgaccgcg ctgttggtgg tgccgaggtc
      181 gatgccgatg gccttcattc ccgctccgtc ccttgctccg tgccgccgtc cgcggcgacc
      241 acaacccggg cggcgcgcag cacttgcccc cggtatcgat acccgcgctg caggatctca
      301 aggacctcgt cgtcggcgct gccgggcggc gcggcgcgca cctcggtcac ctggtgcgtc
      361 gccggttcgg cccgctcgcc gacccgcccg agaggttcga gcccctcctc ggtcagcgcc
      421 gcctccaact gcccggcgat cagcgcgaga ctccttcggt acgcctccac atcgctcgcc
      481 gcgccgtccg ccaggagccg gtcgaaggag tcgagtacgt cggcgcagcg cagcagcagc
      541 cgttcggtga gcgcctgatg ggccgcgtcg cgggcggcca gatcgcgggc gtgctcgtag
      601 gcgagccggg ccgtcgggtc agacatcgaa gcggatcaga tcgtccagga ggcgcgcggt
      661 ggcctccggg agcgggcgct cgggctgctc atcgctcggg acgtgctgct cctgggacgc
      721 ggtctcggcg gccagccttc ggtcgatctc gtcggctgcc aggggcagtt cggcgtcggg
      781 gtccacgtcg tacaggagca ggtcgacgag catcctgcgg cgtacgccgc gcagctcgtc
      841 ccacgcctgc tgggtgaccg gcgtcatcag atgccgggcg agcagctcga aggagacgtc
      901 ccgcatctcg gcgtgggtcg tccagggggt cacaccggcc ggggcgagcg cgtcgtaggg
      961 gaaggggccc tcccagctcg cgtcggggtc cttgatcacg cgacactgcc tcctgcttcg
     1021 ttctcggtgg ccccgtccgc ggggctcagt tcggtgagcc agcggcgcac cgcgtcgagg
     1081 agcgcccgcc ggatccggct gtcggtggga tccgcgcggg tggcgcggat cagatggtgc
     1141 agcgcccaca ggatctcccc gccgcgcagg gcccgctccg ccttgtcggt caactccgcc
     1201 gcccaggagg gcagatcgtc gacgtcgggc ggggtctcct ggccgtcgct gcggatcaga
     1261 tcgcccatgc cgccgacgcc gagatgccgg gtgagcagct tctccatctc gtcgagggcc
     1321 tcgcccagcg tctcgcggta gcggtgcgtc agggcctgtc cgaggcccac gtccaggagg
     1381 tcgagcgcct cgtggaggag ttccagacgg gccggcacct cgtacgtccg ctcgtcgagg
     1441 gtgaagacca gggcccgcgc gaggttgtcg cgggcgtggc tcgactccgg gttgagggcg
     1501 agggcgcggc gcaggtcggc ctcggcgccg tacacgtcgc agcgcatccc gtgcttggtg
     1561 cgggtgtagc cgcgccacac cccgcgcagg gagagcagcg ccgagagctt gccgttcaac
     1621 tggccgagca ggtcgcggtc gagggggtgc agggcggcgg tggccgactc gacgagcctg
     1681 acggcctcgt cgaggcaggg gccgagctgg gcgccctcct cgtcggtgag ggcctcgacg
     1741 cggccgagga ccgtgcggat cacggccttc ttcgagcggg cctgcatccc cgcgtcccgg
     1801 gacacccgca ccagctcccg ccagtgctca agggcctcgt cgagtccgcc gtcgccgcgc
     1861 gtcagggcgg ccctggcgag cgcgagccgt acgtgcacgg ccagttcgac gccgtcctgg
     1921 aggaggcggg cgtgccggcg cggcagacgt acgtaggcgg ggttgcggcg caggaagtcc
     1981 tggcagtggc cgcacccctc cgtgtgcccg gcctccgacg cgggccccgc gcagtcgtcc
     2041 ggcagggtgc tcagcgtgcg caggaccggc agggcgcgca gggcgtgccc gaacttgcgc
     2101 acctcgcaca gggcgaagct ccgcgccagc tcggagaacg cccagcgcag ctcgcgcacc
     2161 gcgtactcac cggggtcctc gccccgctgg gccgccgcgt ccaggctcgc cacgagatca
     2221 ccgagcggcg cctggagccg cagcagccgc agatagcgcg gaccgcaggc cagcgtggcg
     2281 cccgcgcccg gcacagacgg caggccgccc acgtccttca ggacccgcgc gccgcccagc
     2341 tcggactcca ggaggcccgc caacgcctgg taggcggcgg cctgttgggg gcggtcctgc
     2401 tcggtgtgcc gctgctcgta ggccgacagc tggccgaaga ggtgctggct cagctcccag
     2461 cgcagcgacg ccatgtcgtc gtgggtgagg tcgcgttcgt agcagacggc gcgctcggca
     2521 cgccagccgt cccagtactc gtcgtcgctc agcagcgtcg cccagtacgc gagcgccgcc
     2581 tcccaggcgc ccaccgcgtg ttcccaggcg ccgctctgtt cgagctcctg cgcctgccac
     2641 agccgcgccg cggccagtcc gtgcaccacg gccatgtcac cgggcgcctc cctgaggcgc
     2701 cgctcccact cggccgcggc ggcctcgcgg tcccgcgcga ggagcaggag cagcggggcg
     2761 tcccgcggga agcgctcgca cagggtgtcc aggaggccgg gcccctcgtc cggcgagagc
     2821 ccggcgagcg cgtcgcgcag ggcttcgggg gagtgccagc ggtagagcag ggcgtccagc
     2881 tgcaaccgcc gggcgggcag gcgcagccgc tccagcgcga cacgctcgtg ccacgacagg
     2941 gaaccgcgct cgagcagcgc gtacgacgcg ttcttcacca cgtccatgga ggcgccgggg
     3001 tccacgcccg cgtcccggag cgcgagatac ggaaaggccc ggtcctgtac ggcgaagggg
     3061 tcggcgacca ggggagtgct ggtcagcccg tccgcccagg ggagcagccc gaccagccgc
     3121 cgcatcctgc ggcagcgcac gtcggcccgg tccaggacgc cccgggcccg cccgtacgcc
     3181 tcgacggccg cgctccactt gcccgccgcc tccagcaacc tcccctcggc gtaggccaga
     3241 tgggcgtcgg cgtcccggtg ccccgggcac tgccggaagg cgtcggcggc ccgctgccac
     3301 tcctggtgcg cgtcggcgag gcgtccgcgc gcgtaggcgg cgacggcggg ggcgtcccgg
     3361 tgcgccccca gggcgccggc ctcggcggcg gcgcgggccc agtccccttc ggcctcggcg
     3421 agccgcacgc gcgcgtaccg cccgcgcgcg gcggcgtcga cgccgtgcgc ctcctcccgc
     3481 tccagctcct cgtacgcctc gacgacgtgc cgccacgcgg cgctcccctc ggcgccctcc
     3541 tcggcgatcc gggcgcgcgc gtagcgccgc cgcgcggtga cgtcggccca gtggccgtcc
     3601 agcgcgtcgt agacgccgag cgcgtcctgc caccgtccgt ccagttcgtg ggtgcgggcg
     3661 agggcgtaga ggtggaggtg ggtgggttcg tccagcgggg cgccgggggc ggggctcgct
     3721 gcctggccgc tcggcggcgg agggaacgcc cgggcgtaga tctcgcaggc cccgcgccag
     3781 ttacccgcct cctccgcccg acggccctcg gccttgcggc ggagggcgcc caccgcgccc
     3841 tcgcgggcct cgtccggcac gccggtgagc aggctgagca ccgcggtcca gtcggcgcgc
     3901 gaatcggcgg ccacacgggc gcgcgcgtac aggcgccgga cgccgacctc gccgtccgcg
     3961 tacgcgtcgg gcagccgccc gaacccgtcg atgacgccgc tccactcgcc ccgctcgtcg
     4021 gcggcccgcc cccgggagta cagcacccgg tccggcacgt ccgccagctc ggacggcagc
     4081 cccgcgaagt gggcgagcgc ctgggcccag cggccctgct cctggcagag gcgcccctcg
     4141 gcgtacgtac gaaggcgcgg cgcgtcggcg ggcaccccgt cctgagggcc accgcggaca
     4201 accgccccga acgcctccac cgccgcgccc cagtcaccgg cgaccgccgc cgaccggccc
     4261 gccacatagc gccggagcgt ctccgtggcg gcgtacccgg cgggcagcgg ggccaagtgg
     4321 gccgacgcgg tcgcccagtc accggactcc accgccgcga gggcggcctc gtacacctgc
     4381 cgccgcagct cgccgaggta cggctccacg tcgcaaccgc cgtacgcatg caccaccgag
     4441 gggcccggcg cctccggctg ctggtgcgag ccgccgtgct ccggcacggc caccggaccc
     4501 tgcgggccca gctgctgccc cgcaccgccg gcgtcctgct ccggtgcccc cgccggacct
     4561 tgctgctggc gcgggccacc gccgttctgc tccggaaccg ccaccgggcc ccgcccgccc
     4621 agcacgtccc gctcggtcgc cgccgccgac aggtcggtga ccgcttcgac gaggcggccc
     4681 gcgtccgccg cgtcccgccc ccgcgcgtac aggagccgca ccccgctgtc gaggaagccg
     4741 tccgccgccc cgtaagcggt caccgccgcg ccccacgcgc cagccgcctc cgccacccgc
     4801 ccctcggcat acgcgcacca ggcgccccgc tcggcccccg cctgagcgaa cgcctcccgc
     4861 gcgcccggcc agtccccgcc gcccgccgcc gcccggcccc gcgcgtaggc ggcccgcccc
     4921 gccgcgtcct ccaggcccgc gcacgcgccg tacgcggttt gcgccgccga ccagtccccg
     4981 gccgcctcgg cggcacgacc ggccacatac gccgcccacg ccgaggccgt gtcgtggccg
     5041 gggcgcaggg tgaggacggc ggcgtacccc cgtgcggccg ccccccagtc gcccgcccgc
     5101 cgcgcccgtt cggcggcctc gcaggtccgc gccacgtgca gctcgtcgcg cgcggccgcc
     5161 aggcgctcgg cgacatcccg cagcccgccg ggccgcgcgg cgagcacgtc ctcgtaccgg
     5221 ctgatcgcgg tcgcccagtc cgcggccgcc tcggcggtcc gcgcctcctc gacgagcgcg
     5281 gcaagacgct ccagctcggc cacttccccc gccaggcagc ccggtacggc ccccggcaac
     5341 tcccggcgca ccaccgccca ttgcgccgcg gcggccgacg cgtcccgtcc ctcggcgagc
     5401 agcgcgcaca gcttctcgac ctcgtgccag gccagttcga aggcggcctc ggtccgcagc
     5461 cgccgctgct cgtcggcgta actctcgccc tcggtccgca ggatccgctg cacctgcgcc
     5521 cagagcccgc ggtcccgctg gaagcgcgcc gcgccgatga ggacgtccga ggcgacatgg
     5581 ccgaaggggc tctggaacgt ccgcagcgcg tccgcgccct gccgcagcgg gtccggttcc
     5641 gccctgtcgc gcacctcacg cgccttgaag agccagccct ggcggcaccc ctcgtgcagg
     5701 aagagcgtgg gcgtcgccca ctccaccgcc gtgtgctcgg gctggtggga gatgcgcagc
     5761 cgcgccgcgg ccaccgactc gtcgacggtc ttgttggccg cgatgccctt cagcagctcc
     5821 gggctgaacg cgcccgccga cacatcgctg accagccccc gcatcgccac caccgccgga
     5881 acgccgccgc cgatcagcgc ctgcgcgagc ccggagaagg gttcgaggtg cgaactgtcc
     5941 gcgctgaaac agaggttgag cgcgatcagc cgcagccgcc gcgacttcag caggattccg
     6001 ctgagcacat ccgcgggcac ccggtcgacg ccgccgctcc gcgtctccag ggataccacg
     6061 cccttgccca gctcctggtc gtactcgccg tgcgcgatca gtacgacagc cgtggggagt
     6121 tcggggtcag cggcgagcgc cgacgccagg ttcgcacgcg aggcacgctc caacacggtg
     6181 gtcttcacgg cgacgtcggg cagatcgtgg cggagcgccg ccacctccgc cgaggtccgc
     6241 agccggggga ggtcaccggg cgacgcgcag gccaccagga gccggatcac gctcggctcg
     6301 tccgccggat cgggcagccg ctgtccgagg gggccgcccg gcagtgagcg cgccagcgaa
     6361 taggcgtggt tgagcgcgaa cgcctgctgg gggctgccgg gcgggccgca cagcgactcc
     6421 agcggaaggt cgcgcagctc gggcggcagg tcgaagcgga gccggagccc gcgctgcctg
     6481 gacatgccct gggcgcggtc gaacgcggcg tcgacgcaga cgccgacgcg agtgccgatc
     6541 tcctcgcggc cctcgccccc ctcgcgggcc tcgtcgtcac cccccgcacc cgcctcgccg
     6601 cccgcgtcct cctccggttc cgccccctcg ccgccgaaca ggaggcggaa caccccgcgc
     6661 cccagctccc gcagctgcgc cacggtgtgc tgatcgccca tcggggcgag gcagagttcc
     6721 gcggcgatca gccggtccca ctgctcgcgg aggaccgcgg gctcctcgcc gaccgtgatg
     6781 atctcggcgg cggccgcggg gccattggcg gtcaccagat agcggtcgcc gcccacgcgg
     6841 cggacccgga tgcgcagttc ctcgtacgcg agcacggccg tcactgctcg ctctcgtcgg
     6901 gctgccacat gacgtggttc agatcggtca cggcggcttc ccgctgctcc tccaggtcgg
     6961 gatcgtcggg gaagtacgtg agagcggcgg tgagttggtc gatcgcctcg cgcaaggtgg
     7021 cccgcgcgcc ggacaggctg cccgaggccc agcgggcccc cgcgaggcgg cgcagcacga
     7081 tgccgaggct gacctgtgcc cgcagcaggt gcgggttgaa cgcgacggag cggcgcaggt
     7141 cggcggcggg ctcgtcgagc agcgcgtcct cctcgttggc cacggagatg gcgcggtcgg
     7201 cgaggacccg ggccaactgg ccctccaggc gtccccgttc attggcaccg atcaccgagc
     7261 gggtcgcctc cagggtggag accgcgcgcg tcaaccgccc ctcgcggtgt gcggcgcggg
     7321 ccgctccgag cgccatgtcg acgatggcgg tctgcgtctc gcggtagcgg tcgagctggc
     7381 ggctgtggac cagggcgcgc cgccagtagg cggccgccgc cgcgaagtcg ggccggtccg
     7441 cgacgagttc gacgcgtccc atgctgagcc gcgcctccag ggcgagaccg cgcgcgtcga
     7501 gggagagcct gcggtgcttg tccggcagcc cggcgtaccc ggggttcagc tcgtcgaagc
     7561 gcgcgcactc cggctcgcac acggccgccg caccgggccc gctgccccgc gcccggcagc
     7621 cggggcagcg cagctcggag agcgcggcga gggcgtcggc gggcttgccc atgcccaaca
     7681 tcagctgagc gaagccgagt tcggagaacg cgtaggtgag ggaggtgtac gtgggtgggg
     7741 tgccggaggc cggggcggcg agggcgtctt gcgtaccctc ggcaggatgg gcggctttct
     7801 gcgaggcgac gccgtcggcc gggaacgcct gcccctggcg cgcggcgccg aacgcggcgc
     7861 ccgcttgcag catccgggcc tcctgcgcgg ccgcgaacgc gccgaactcc gccgacctgc
     7921 ccagctcggc gatgcgcagc ggcccgcaga ccagcggcgc cccgccgccc tgggccgacg
     7981 ggaaaccgcc cgcggcggcg agcagcttcg cggcgtcggc ctcgcgctgg agcagggcgc
     8041 cgggcgctac gcgcgtaccg gcgtcgtcgg gcaggcggcg ctccagcgcc tcgcgcagac
     8101 cggcccggag cacgggtacg agggacgcct ccaccgccac gtcgtaccgc cgcgcggcgg
     8161 tggcccgggc ccgctcccag aaccccgcgt cgtgcagcac ggccgcccac gcggcgacgc
     8221 accgctccca gtgcgaaccg ctcggctcgc ccagagagtt gagcagggcc agggccaagg
     8281 tatgggtgac ccggtgatcg gcggggtcgt ctcgtacggc ctctccgagc agttccacgg
     8341 cggcggcgcg ccgaccgccg cgcacgagca ccacggcgtg cagcggggcg aagccgtccg
     8401 gctcccggtc gagcgtccga gcggcgtcga ccaacgcccc ggcccgctcc cacccggcct
     8461 tctcctccgc gtcgtcgctg ccgttgcagt ccgtgcgtgc ggcgcgccgc acgcccatca
     8521 gcccccggag cgcggccctg cgcagccgca acgccacctc gcgcgcgggg cggccggaga
     8581 gcgccgccat gacccagtgg gcctcgtcgt ccagcggcgc gatgcgggag gcggcgcgca
     8641 gatcgcggag agcggcgtcc ggtgcgcccg cgcgagcgtg gacgtacgcc cgttggacca
     8701 ggctgcgggg gtgcggggcc gggcaggcga gggccgcggt gaggtggcgc tccgccgcgg
     8761 cgaggtcgcc ctggtgcgcc gcggcgcagc ccagccagtg caggggcccc gcggccgtgg
     8821 gccgcagcct ccgcgcccgc tcgaactccg cgaccgcctc ggcgacttcc ccggcggcga
     8881 gccgcacccg ccccaccccg gtaagggccc gcgccacgac ccgcaccgct ttcccgccgg
     8941 ggccccggag ccctacgccc ccctgcgact caccggcacc gtccccatcg gcgcggcttc
     9001 ccccgctgcc gtcgccgccc tgttcagcgg ggctgacgcg gttctccgta ccgccgccct
     9061 cgaagctttc ttcacccccg cccgccccac cccggccatc cccctccccc gccagcgaca
     9121 acgccttccg gaagtgctct tccgccctcg cgtgctcgcc gcgcttcagt gccgactccc
     9181 catcggcgca cgcctgttcg gcaccgagca gctctgtggc tgtcgtgtcc gtcgtgtccg
     9241 tggtgtctgc ggtctgcgca gtcacagtca gcccccgatc cgcggcgagc ggcccgccgc
     9301 gtcctccggc cggcgcgtca gccggcggcc tcgtcaagga ccgagcgcca gcggccctgg
     9361 gcgcggtcgt agtgcagcgg ccccaccgtg aacttggcca ggtccagcgc gacgagcgac
     9421 tcgtaggcct cggcgggaag gtccggttcc agcacgatgc tcagcccgcc cgcgggatcc
     9481 tggagcacca gcggccgggc cccgccgtcc gtggccgacg ccgggcgcgc ggtcctgcgt
     9541 acgaccccct tgaacgcggc gtacgcgtcc ttgaccgcct ccgccccgag gccgctgagg
     9601 aacgcctgca acggcaggga ggccagcacg atccaaggga tgtcggccgc cccgcggtgg
     9661 acgagggtgc ggcggacccg gaccggcggg gcgccgagcc ggtcgaacgc ggcgaccagc
     9721 tcccggccga ggtcttcggg gacgtcgcgg tccaggagca gctccgctcg cggcggcgca
     9781 tcggtcatgg aggtgattcc ttccggggac gtggaccgca gcctagaggc gtgagccgtg
     9841 cgtacgtggg gaaaccggtg attcagcgcg gcgcatcaag gccgccaccc cctacccccg
     9901 tgcgccctct ccgcgccccc gtacgccccc gattcacgcg atggtgcgat catgtgccgc
     9961 cgtccggatg ccgggggaga gccacgggta gggccgggcc atgacgcagc ctttcgaact
    10021 gccgcacttc tacatgccgt atgccgcgcg gctcaacccc cacctggagg aggcgcgcgc
    10081 gcactcctcc cggtgggcgc gcgacatggg gatgctggaa ggctccggaa tctgggagca
    10141 gagcgacctc gacgcgcacg actacggcct gctgtgcgcg tacacccacc ccgactgtga
    10201 cggccccgcc ctttcgctga tcaccgactg gtacgtgtgg gtgttcttct tcgacgacca
    10261 cttcctggac atgtacaaac gcacgcagga ccgggcggcc ggaaaggccc acctggaccg
    10321 gctccccctc ttcatgccga tggacctctc gacccccgta cccgagccgc ggaacccggt
    10381 cgaggcgggc ctcgccgacc tgtgggcccg cacggtcccc gcgatgtccg cggactggcg
    10441 ccgccgcttc gccgagtcca ccgagcacct cctgaacgag tcgctgtggg agctgtcgaa
    10501 catcaacgaa ggacgggtcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgccccc tggtcggcgg gcctcatcga gtacgcgacc gccgaagtgc ccgcggccgt
    10621 cgccgggtcc aggccgctgc gcgtgctgat ggagacgttc tccgacggcg tccacctgcg
    10681 caacgacctc ttctcgtacc agcgggaggt ccaggacgag ggcgagctga gcaacggcgt
    10741 gctggtcctg gagaccttct tcggctgtac gacccagcag gccgccgaca tcgtcaacga
    10801 cgtcctgacc tcgcgcctgc accagttcga acacacggcg gtcaccgaag tacccgccct
    10861 cgccctggag aaggggctca ccccggccga ggtcgcggcg gtcgccgcgt acacccgggg
    10921 ccttcaggac tggcagtccg gcggccacga atggcacctg cgctccagca ggtacatgaa
    10981 cgagggcgcg ctggccacct caccgctcgc cggacccacc ggaatcggca cctccgccgc
    11041 cgacgtgggc gcgctgctcg cgtccgccgg ggcggagcgg ctgcgcgcct tcacgcacat
    11101 cccgttccag aaggtgggcc cctcgatcct cccggacttc gagatgccgt tccccctgcg
    11161 gctcaacccg cacctggacg ccgcgcgccc gaggctcacc gcctggtcgc acgcgatggg
    11221 catcctggag gagggcgtct gggacgagga caagctcgac gcgtacgacc ttccgctctg
    11281 cgccgccgga atcggcccgg acggctcggc ggaagcgctc gacctcagct cgcagtggct
    11341 ggcctggggc acctacggcg acgactacta ccccctggtc ttcggccacc gccgcgactt
    11401 cgccgccgcg aggctctgca cggagcgcct cgccgggtgc atgccgatcg agggcgagcc
    11461 gctgaccgtg cccgtgaacg ggatggagcg cggcctcgcc gacctgtggg cgcgcaccac
    11521 ccgggacatg accccggagc agcggcgcac cacgcggcac accgtggtgg tcatgacgga
    11581 gagctggctg tgggagctgg ccaaccagct acagaatcgt atccccgacc cggtcgacta
    11641 cctggagatg cgccgggcca ccttcggctc cgaactcacc atgagtctgt gtcggatggg
    11701 ccacggcccc gccgtgccac cggaggtcta ccgcagcggc cccgtccgct ccctggagaa
    11761 cgccgcgatg gactacgcga tgcttctcaa cgacgtcttc tcgtaccaga aggagatcga
    11821 gtacgagggc gaggtccaca acggcatcct ggtcgtgcag aacttcttcg gctgcgacta
    11881 cccgaccggg ctgaaggtca tccacgacct gatgacacag cgcatgcgcc agttccagca
    11941 tgtcgccgag cacgaattcc ccgttctgta cgaggacttc gggctctcgg ccgaggcccg
    12001 cgccgtcatg gacggctatg tcaccgagct gcagaactgg ctggcgggca tcctcaactg
    12061 gcacgcgggc tgccgtcgct acggcgccga ggacctggcc cgcagggcgc acggcttcct
    12121 gccggaccgc gcgccccggg tcccctcgat cgccgggctg cgctgaccgc tgcccggcga
    12181 gacgaccggg caggccgcgc gcgtaccgcc cgggccgact aggcgggcac gcgcgcgtgc
    12241 cgcacggcgg cccgtgccag accccggatg accgggtgcg ggcgcgagcc gtcgccgaac
    12301 agctcgggct ggaagagggt ggccaggaag aaggggtggc cggggagttc ggcgatgcgg
    12361 acccggccct cctcgtcctc gcccgtgaag cgcaggccgt gcgcgcgcag cgtgtcgagg
    12421 tgggggcccg ggccgtagga gcagtggtag cgctcgacgg accggtcggc gccgagcagg
    12481 gactcggcga gcgagccggg ggcgagcgtc accgtgccct cgtgcccgac cagcgagcag
    12541 gcgagcggct cgatgagcag gtcgtcggcg ccggggtcgt tctcggcgtg cgcgacatcg
    12601 gaaaggccgc acacgtggcg cgcgtactcc agaagcgtgt gctggaagcc gccgcaggtg
    12661 ccgaggaagg ggatgccctc ctcgcgcgcc gtgcggatgg cggtcagcgc gcccgcctcg
    12721 ctgcggtagg ggctgccggg caggacccac accgcgtcga aaccgcgtac ggcgtccggg
    12781 tcctcggcgt cgtcggtcgc gacccagtac gcgtcgagga cgaggcggtc gtgggcggcg
    12841 agggcgtcca ggagcagcgg catccggttg tgggaggtca cgttcggcga gcgttcgccg
    12901 atcaacgcga cccgggccgt gggggagtgg tgcgcgtggc ggcccgcttc ggcgccggtc
    12961 atggctgtgt cggtcgtcat gccgatcatc ctgggcgcga cctgtcgttc acgtccaacg
    13021 atgaaatctg catcctccat aagcgatcct gatggggtgc gcgatccttg gccgcatgga
    13081 tccgcatctc ctgcgtacgt acgtgacggt ggcccgcctc gcctccttct ccgaggccgc
    13141 gcgcgcactc ggctacaccc agtccgccgt ctcccagcac atcgccgccc tggaacagga
    13201 cctcggttcc gccctgctga cccgccgccc cgtggccccc accccggccg gcgcacgcct
    13261 cctggaacac gcgggtccgc tgctgctgcg cctcgacgcg gcccgcgccg aggtcgtgcg
    13321 catggcgagc gcccccgagc acggcctgac gctggccgcc acgccgaccg ccctgacccg
    13381 gcgtacggcc gaggcgctgc ccccggcggg cgtcaccctc tccgtgctgc cccgcgacga
    13441 gatccccgct gccgtcgcga ccggcgccgt cgacctcggc ctcgtcgacg gcctcgccgc
    13501 gccgaacgac ccgctgcgcc tgcccgacgt ggcacccctc accgcgcggg gcaccggcca
    13561 ggagcccgtc gccgtcctgc tccccgaagg ccacccgctg gcccgccgca ccggactgcg
    13621 cctcggcgac ctcgtgcacg cccgctggat cgacgccccc ggcaccggcc tgccgctggc
    13681 ccaactccgc gccgcgaacg gcacatcggg cttccggccc gcgctgcgct acgacggcac
    13741 ggacctgcgt accctcgccg cgctcgccgc cgcgggccac ggcctgaccc tgctgccgcg
    13801 ctcggccgcc gccggggtgc ccggcacggt cgccgtgccg ctgaccgcgc cccgcgtcgt
    13861 ccaccgcacg gagctgctcc acgcgggcac cctgcgcggg gccgccgcgg cgctggcggc
    13921 acacctggac gtcacccgtt cgtgaggcat cgccgcaggg gcgcgccggg tagggctgtg
    13981 gccggaggcg agccatggaa cagaccgcgt tgcgtcccaa gccgatgcca ggccggagcc
    14041 ccggccacgg cccaggcgac caccccgaga aggaccgtcg gccatacgcc gtgcggcgcc
    14101 gaggcaggcg agtgccggcc gtgctgtccg gactgctcct cgcggtgctc ctggtccttg
    14161 cgggtatcgg catcggcgtc ggagccgtgg gcgccaccgt cctcgacgtg agcgggctcg
    14221 ccgggacagg ggaggccgcg tccccgacgg gcgcgccccg gccgaccgcc gggggccctg
    14281 agtccgaggc accgaagccc gaagcgtcca agcccgcgct gaagtccgcg ccgccgaagt
    14341 ccgccccgcc gaagtccgag gcgcccaagc ccggaccgcc gaagcccgcg ccgcccaagt
    14401 ccccgcaagc cgggcccgcc tccgccgcga agcccgccag gacctccacc ctcggtgtcg
    14461 aggccgtgga cgcccccggc ggcgcgggcg ccctgctcgt cggcgtgcac ctcccgggcc
    14521 ccggccacag cgcgggcctg gtgcacggcg acaccctgct cgcgttcggc ggaacccgcg
    14581 tcggctcggc ggccgccctg gcgtcggcgg tcgccgccgc gcccccgggc acgcaagtga
    14641 cgctgacggt ccgccacaag aacggcgccc gccagacgct cgcggtgagg ccgggcatcg
    14701 tgacctgacc cctgacccct gaccgcaggc gtcagccgaa gtccgtgcgg ggcccactgc
    14761 gcggctcgcg ccccgggtag taggcgagga cgtcgtacgg atacggcagc ggccgcgcac
    14821 tcgccgacgt cagccgctcc tgctgctcag acgtcaactc ccagtccacg cagccgagat
    14881 tgtccgccag ctgctccacc gacctggccc ccacgatcgg cgcggtcacc ccgggccgct
    14941 ggaggagcca ccgcagcgcc acctgggacg gcgtgcggcc ggcttcgtcg gcgacctcca
    15001 ggagcgcgtc gacgacccgc cacgtctcct ccgtgttccg ctcccgccag gcgcccgaac
    15061 cccgcgcgcc ctccggaggc gcggccatgg agcgccggaa cttgcccgag agccagccgc
    15121 cctgcaaggg gctgtacgga atgacgccca cgccctccgc cgcgctgagc ggcagcagct
    15181 cccactcgct ctcgcgcgcc aggaggttgt agagcggctg gagacaggag tacggctccc
    15241 agcatcgggc ccgtgccacg tcaagggcct tctgcagctg ggccggggag tggttgctcg
    15301 ccccgagata gcgcaccttg cccgccttca cgagggtgtc cagcgtggac agggtctcct
    15361 cgatcggcgt cgtcgcgtcc catacgtggg tctggtacag gtcgatgtag tcggtgccca
    15421 ggcggcgcag gctcgcgtcc acggccgaca ggatgtgctt gcggctcagg ccgcccgcgt
    15481 tcggggattc gcccatcgtg ctgaacacct tggtggcgat gacgagttcg tccctgcggc
    15541 ggcccttgag ccagcggcca aggacctctt ccgacacgcc acgcccgtac atgtcggccg
    15601 tgtcgacgaa cgtgccgccc gcctccgtga acgcgtccag catgcggtgg gacgtcgtct
    15661 cgtccgcgcc gctgccgaac atcatcgcgc cgaagcacag ctcgctgacg cgcagcccgg
    15721 tccggccgag gaatcgctgc ttcatggcct gccctcccct gagtaggcac cccaagatag
    15781 gcgctccgtc cgacaaggaa ggaaggcgct cacgcggggc ccaggacggc acacgactcg
    15841 gcgggcagcc gcagcaggcc gtccgcgccc ggcggctcga ccggctccca ggcggcgagc
    15901 acgcgcgcgt ggttgtgccc cagcgggacg gcggctgcct ccccggcgag gttcacggcg
    15961 atcttcaaat ccccgcggcg gaacgcgaac cagcgcgccc gctcgtcgaa ggcgacccgc
    16021 accgccgcca ggtcggggtc catcaggtcg gcgcgggcgc gccgcaggga gatcagctcg
    16081 cggtgccagg cgagcacgcg cgcgtggtgg ccggtctccg gctgcgacca gtcgaggcag
    16141 gaccgctcgc gggcggccgg gtcctgcgga tcgggaatgt cctcctccgc ccagccgtgc
    16201 gcagcgaact cccgccgcct gccccggcgc acggcctctg ccagctcggg atcggtgtgg
    16261 tcggtgaaga actgccaggg cgtcgtggcc ccccactcct cgcccatgaa gagcatcggc
    16321 gtgaacgggc ccatgagcgt gagcgcggcc gcgcaggcga gcaggccggg ggagagggag
    16381 gcggagagcc ggtccccctg cgcgcggttg ccgatctggt cgtgggtctg cgcgtagccg
    16441 aggaagcggt gggcgggggt ccgggcgcgg tccacggggc ggccgtgggc gcggccgcgg
    16501 aacgtcgagt acgtgccgtc gtggaagaag ccgcgcgtca tcgtcttgcc gagggcggcc
    16561 agcggggccc gcgcgaagtc ctcgtagtac ccctgcgcct cgcccgtgag cgcggtgtgc
    16621 agcgcgtgat ggaagtcgtc gttccactgc gcgtgcaggc cgaggccgcc tctcgcgcgc
    16681 ggcgtgacga cgcgggggtc acccaggtcg gactcgccga tcagggagag cggcctgccg
    16741 aggtcgtcgg agagggagtc gacggccgcg gacagctctt ccaggaagtg gcacgcgcgc
    16801 gtgtcccgca gcgcgtgcac ggcgtcgagg cgcagcccgt cgagccggta gtcgcgcagc
    16861 caggcgagcg cgctgccgac cagatacgcg cgcacctcgt ccgagccggg cgcgtccagg
    16921 ttgacggcgg cgccccaggg cgtgtggtgc gtctcggtga agtacgggcc gaaggcgggc
    16981 aggtagttgc cggaggggcc caggtggttg tggacgacgt cgaggaccac gccgaggccg
    17041 agcccgtgtg ccgcgtcgac aaatcgcttc agcgcctcgg ggccgccgta cggctcgtgc
    17101 acggcccaca gggacacccc ctcgtacccc cagccgtgcc gccccgggaa ggggcacagc
    17161 ggcatcagct ccacatgggt gacgccgagg tccgcgaggt ggcgcagccg gtccgccgcc
    17221 gcgtcgagcg tgccctcgcg cgtgtacgtc cccacgtgca gctcgtacag gaccgcctcc
    17281 cgcacgccgc gccccgccca gggcgtccgc cacgcgtacc ggtcgtggtc gacgaccgcg
    17341 ctcaggccgt cggggccgtc cggctggcgc cgcgagcggg ggtcgggcag aacgggaccg
    17401 ccgtccaccg agaagccgta gcgcgtgccg tcctcggcct ccgcctccgc ggtccaccag
    17461 cccgcccgac cggcgtcgcg ctccatcgcg cgcgtggcgc ccgcgcactc cagagcgacc
    17521 cgctcggcct gcggcgccca cacttcgaac ctcaccgacg tgccccctcg tccgctgtcc
    17581 gtcacacctg cgtcccatgg tgcgtcagaa gtgctctgtt ggggggcgga agagatcgat
    17641 cggccgccgc cccggcccat tctggacacc cggggcgagc ttgcccgaca atccccaggt
    17701 gacatcctct ttcgagttct ccacataccc cgcgcgggtg acggacgccg agcgcgaccg
    17761 ggcgctggac gcactcaagg agggcgcggc cgtcggcagg ctctcgcacg acaccttcct
    17821 gcggcgcatg gaactggtcc tcgccgcccg caggcccgac gaactcgccg ccctcaccgc
    17881 cgatctgcgg accgagggcc gctggtcgcg catggtgctc ggcagcgtgg aagcggtctc
    17941 cgggttcacg atgaagctgc gcagggcctg gcaggccgag cgcctgccga agcttctgct
    18001 gccctcgccc gacagcccct atccgctgcg gatcggccgc gacccggcca acggcctgcg
    18061 gctcagccac gacacggtct cgcgcgtaca cgccgagctg cgccggcagg gcggcgtctg
    18121 ggtactgcgc gacctcggct ccaccaacgg cacgtcggtg aacggccgcc gggtgaccgg
    18181 ctccgccctc gtccaggacg gcgacctggt cagcttcggc cggatggcct tccgcctcgc
    18241 cgtgagctga gccacggccc ggcgcgtccg gggcggtcgc gggccccacc actcacttca
    18301 ctcacctccg cacgcgcgag cgtggcgtgc ggcggccacc gtcgtgcgtg actggtgttc
    18361 gatctggtgc tccagtggca cccagcgcgc cccgaaccgc tcggcgaggg cctcgctcca
    18421 ccgggtcacc agccggtcga ggcgtggcgc cgcccggtcg tccgcctcgg tcaggacccg
    18481 cagcagcatc gccgccgccc gcagcggcag gcgccgcccg aacgcgtcga cgctgccgat
    18541 gtacgccacg gtggtgctcg cgggcggcag cctggcccag tcgtcggcga ggccgggcac
    18601 cagcgcgagc gcccagcgcg ccgcccgcag cagcggcccc tcctcgccgg gcagccgggg
    18661 cagcgcctcc gccaggacct cctcgacgag ccgcccgtcc ctgcgcagcc gccgcgcgaa
    18721 cgcccgcatg gccggtcccg gtgccgggtg cgccgccggg tcgtcgacga ggtcgctcgc
    18781 ccacatcggc acctcgacga tcgcggtgcg gccgccgtac cggtgggcgt ggtgccaggt
    18841 ggtgagccgg gcgtcctcgg ggaggctcgg gtaggcggcc tgtgccccgg ccgcgggcag
    18901 tacgtggacg cccggccccg agaccggcca gcccgcggcg tccgacgccc ccgtctccac
    18961 cggaatgtgc agctccgccg ccgacttggc gaacggctcc gcgagcccgg ggatgtcctc
    19021 ggtcagctgc acccagctgc cgcccagatc ggtgcagtgc agggacacct gcaagtaggg
    19081 ccgcagttcg tcgatgacgg cggtcagggc gcgtgtctcg ggcggcagcc ggtgaggggg
    19141 cagcacggag ggcgaccact cgggctgctc cgggcccgcg gggcggaaga agtgccggtg
    19201 gtagtcgagg agcgtgcgcg gggcgggcgt gcggtgcagg ctcgcgccgt ccgggtcggc
    19261 gcagagcagg aagtgccagg aggtgtcggc gcgcagtcgg ggatcgcgca gggcccgctc
    19321 ggcgaggtgc agcagggtcg agccgccgat cggctcgttg gcgtgggcgc ccgcgacgac
    19381 gaggaccgca cgggaggcgt gccccacgga cagcaggtgc aggggccgcc ccgcgcgcga
    19441 ggcgccgatc tggcgcaggg tgctcagttc gggacggtgg gcggccaatt gccgtgcgga
    19501 ggtgatgagt tccgggacag tgggatagcg ctgcaccgcc agttgactca cccccgcctg
    19561 gtccgccacc gccgcaatcc gcagtacgcc acgcccccgg gcaggtgtca aggaaacgga
    19621 cgccgggggc atccgtgcgc cccccacacc cgtacgcccg tacgaaaacc acgcgctccc
    19681 ggagccgacc gggggacggg gtcggccgcg ggccgcgcag tacaccctcc gcccgtcccc
    19741 ctggcacccg gcgccaggct caaggcgcgg cccctcagag cccgtcggcc tctcccccta
    19801 tgctctccgg ggccgaatct cctccagagt cggcgatccg ctccaggagc gtcaccggcg
    19861 aggccgtgaa aaggtccgcc acgcgcgcgt ggccctcgaa ctcccggccg ggggtcagca
    19921 gatccgtcca tcgccctgcc ggaagcggaa gttccgtctc tcgccagcca ccttcctccg
    19981 ccagccgcag ggacagccgc gtcaccgcga ccaccacctc gccggagcga gcgaacgcca
    20041 cgcagtgcgc ggcgccgggg ccctcggccg tcaggggttc gtaggtcccc gcgtccccga
    20101 acagctccgg gcgccgcccg cgcagccgca gcgccgccgc ggtgagcgcc agcttctcct
    20161 ccgagaggtc agcgcgctcc ggccgcgcgt cgagccgctc cagggccttt ggccgaaagc
    20221 gcgcgggcgt ccggttgtcc gggtcgacca gcgcgcggta ctcaccctcc gtcccctgat
    20281 agaggtcggg caccccgggc atcgtcagat gcaggagcgc cgcccccagg acgttcaccc
    20341 gcacatgggg tgccagctcc cgcgcgaggg ccgcgacggc ggactgcggc gccccgcacg
    20401 gccccgcctc cacaaaggcc cccacggcct tctcgtacgc ctcgtcgggc tcggtccaac
    20461 tggtgtgcag ccccgcctcc cgcacatgct tcaggagcgc gtcccgcagc cgtgtgtcgt
    20521 ccgggacgcc gaagccgacc gccgtctgcc aggcggccca cgccagctgg gggtcgggcg
    20581 cgcggacgcc cccctcgcgc gcggtccgct ccgtcacctc ggcgagaagg gcggcccagc
    20641 ggtccgggca ctgcgccagg acggagatgg ccgcgcgcac gtcggcgctg cgcttggtgt
    20701 catgggtcgt caggaccgtg cccgtatagg gccagtcgcg ctgcacgcgc gcgcagtacg
    20761 cgtggaactc ctccacggag accgcgggtc gctcgggcgc cccgcccacc tccgccgccg
    20821 acaggagcgg cgcgtgccgg tagaacgcgg tgtcctccac ggccttggcg cgcagcgcgg
    20881 acgcggtctg cgcgaaccgc gcgcggaacg ccgccaccgc ggccccccgg ctcccgtcca
    20941 ccgccccggc cctgccaagg accagatccc gtacgacatc gaccgtccgg gcctcctcgg
    21001 gcacgctgaa ggcggccctg gcctccgcgg cggccgccgc ggtcaggacc gtctcggggg
    21061 cggcgccccc ggacacgtaa ggccggtaga cgggaagccg cacgagcagt tcccgcaggg
    21121 ccgtgcgcag cgcccacggg gcgtggtccc gcagggtggg gtcggccgcg cagatcgcgg
    21181 cggccgcgcg cgtgagacgg tcgacctcgg cggccagctc gtgcgtgatg acccggtacg
    21241 cggcgcggcg caccgtcgcg gcccactcac cgccccggtc ggtgggcggc gcggcgaagc
    21301 ggcggtactg gccgaggagt tcccccgtgc ccgccgggtc ggtgaggacg ccgtcgagat
    21361 ggcgcagcgc gtcgtagccg gtggtgccgg cgaccggcca ggcggcgggc aggtgctcgc
    21421 cgtcgccgag gatcttctcg acgaccgtcc agcgcccgcc ggtcgcctcg tgcaacttct
    21481 ggaggtaggc ccccgggtcc gcgagcccgt cggggtgatc gatccgcagc ccgtcgacga
    21541 cgccttcgcg gagcagctgg aggatcttcc cgtgggtcgc gtcgaagacc tccggctcct
    21601 cgacgcgcac gccgatgaga tccgagatgg tgaagaaacg ccggtagttg aggtccgtac
    21661 gggcaagtct ccaccaggac aggcggtacc actgggcgtc cagaagctcg ggcagcggca
    21721 gcccttccgt gccctcgcgg atggggaacg cgtgttcgtg gtagcgcagg acgtccccgt
    21781 cgacccgcag cgccgtcagc tcgtccccga gccgcgcccc caggaagggc agcaggacgc
    21841 gtccgccgcc cgcctcccag tcgatgtcga accagcgggc gtacggcgaa cggggcccct
    21901 cgcgcagcac ctcccagagc gcgtggttgt ggcgcggcac cgccgccatg tggttcggca
    21961 cgatgtccac gatcaggccg agcccggcct cgtgggcggt gcgggcaagg gaccgcagcc
    22021 cgtcctcccc gccgagttcg tcccgcacgc gcgcgtggtc gacgacgtcg tagccgtgcg
    22081 tcgacccggg gaccgcctgg aggaccggcg acagatgcag atgcgagaca ccgagcgagg
    22141 cgaggtgggg taccgcggcc tcggcg
//
