LOCUS       NZ_CP029617            21056 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6190684
            Orig. end                         :: 6211740
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="20"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            2763..3614
                     /locus_tag="DMA15_RS27740"
                     /old_locus_tag="DMA15_27715"
     CDS             2763..3614
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004982656.1"
                     /locus_tag="DMA15_RS27740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27715"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_125515463.1"
                     /transl_table=11
                     /translation="MAGSAEQARHWRYAALPGVDLLRARYIHKTFVRHTHEHFVIAGIA
                     EGVDVFRHGGADQHAGPGTLALVNPDTPHTGRAGVPEGWRYGAVYPAPEVVAGIAAETT
                     ALRGAPGFVRPVLDDPHAVALVHRVLRAAEEGNALAADTLLRVAVTRLLRLNGGRLPQR
                     AVRTAGAGTAARARAVLEERLADPPSLSRLAADLSVSPFALLRAFRDAYGMPPHAWLTD
                     ARVRRALRLLDAGTTPADAATAVGFTDQPHLSRHFTRIVGVPPGAYQRERKNVQDRWRQ
                     RS"
     gene            3765..4523
                     /locus_tag="DMA15_RS27745"
                     /old_locus_tag="DMA15_27720"
     CDS             3765..4523
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191021.1"
                     /locus_tag="DMA15_RS27745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27720"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_240660268.1"
                     /transl_table=11
                     /translation="MGVGVAVGLSGFAFGVTSAGSGLTVLQSCLLSLLVFTGASQFALV
                     GALAGGGNPFTAAAGAFFLGVRNAFYGLRLSQLLALPRAVRPLAAHWVIDETAAVSLAQ
                     PTRRAARIGFTVTGLSLYVLWNATTLLGALGAEAIGDTDVWGLDAAGPAVFLALLAPML
                     RTAADRSVAAVAVVLGLGLLPFLPTGAPVLVSALAVPIVLSVEGRKLRAGRKHEEGHDM
                     HEEGRDMHEEGGDMHEEGPEEPDVPRREDP"
     gene            4520..4828
                     /locus_tag="DMA15_RS27750"
                     /old_locus_tag="DMA15_27725"
     CDS             4520..4828
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973260.1"
                     /locus_tag="DMA15_RS27750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27725"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_125515465.1"
                     /transl_table=11
                     /translation="MSIWIAIGVTVVGCYVVKLVGLLVPAGALERPLVKRVAALVPVAL
                     LAALTAQQTFAEGRVLLLDARAAGLAAAALALLLRAPFLVVIGTAVIVTAGLRALTG"
     gene            complement(4840..5799)
                     /locus_tag="DMA15_RS27755"
                     /old_locus_tag="DMA15_27730"
     CDS             complement(4840..5799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481457.1"
                     /locus_tag="DMA15_RS27755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27730"
                     /product="hypothetical protein"
                     /protein_id="WP_125515466.1"
                     /transl_table=11
                     /translation="MAETGASPDPVPSPDGASSPVARAEHFVWLTARVLEQRRFAYHFL
                     DESRRAADAVETALAAYDTPDGGYGYALEPDLRGPVSQPLHTGHALRVLDAIRRCGGQR
                     VERVCRYLTSVSTPEGALPAIHPSQRGYPSAPFVPVVDDPPGELLATGPVVGLLHRNEV
                     WHAWLFRATDFCWAAVESLEKSHPYEIQAAVAFLDGVPDRSRARATADRLGRLVREQRL
                     AALDPDDLDAYPVSPGYAPGEHHFAHDFAKAPDSLAREWFTDAEMERSLDFLAAEQQED
                     GGWPVRWRQWAPGTALESRPIVTIEALRTLRAYGRPIG"
     misc_feature    complement(5817..5828)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.7"
                     /tool="antismash"
     gene            5879..6073
                     /locus_tag="DMA15_RS27760"
                     /old_locus_tag="DMA15_27735"
     CDS             5879..6073
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611871.1"
                     /locus_tag="DMA15_RS27760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27735"
                     /product="DUF3046 domain-containing protein"
                     /protein_id="WP_030778522.1"
                     /transl_table=11
                     /translation="MRLTVFWQRMAAHFGAGYADSFARDHVMAELGGRTVHEALDAGWE
                     AKDVWRAVCTAMDVPAEKR"
     gene            6353..7519
                     /locus_tag="DMA15_RS27765"
                     /old_locus_tag="DMA15_27740"
     CDS             6353..7519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535897.1"
                     /locus_tag="DMA15_RS27765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27740"
                     /product="AI-2E family transporter"
                     /protein_id="WP_125518035.1"
                     /transl_table=11
                     /translation="MPRWLPRAMVLALALIACFQLGSWAFHQLTGLLINVLIAFFLALA
                     VEPAVSWMAARGLRRGFATFLVFMGVVIASAGFVTMMGSMLAGQIVDMVEDFPDYLDKV
                     ISWINQTFHTDLSRVEVQDSLVHSDWLQKYVQNSASGVLDVSAQVLGGLFQLLTILLFS
                     FYFAADGPRLRRALCSVLPPAKQAEVLRAWEIAVNKTGGYLYSRGLMALISGVAHYILL
                     QTLDVPYAPVLAVWVGLVSQFIPTIGTYLAGALPMLIAFTVDPWYALWVLIFVVIYQQF
                     ENYVLQPKLTAKSVDIHPAVAFGSVIAGTALLGAVGALIAIPAIATLQAFLGAYVKRYD
                     VTDDPRVHGHRRRVGPTLLARVRRALRGPNNPDAAAEAETRPKPDGRL"
     gene            complement(7558..8697)
                     /locus_tag="DMA15_RS27770"
                     /old_locus_tag="DMA15_27745"
     CDS             complement(7558..8697)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883942.1"
                     /locus_tag="DMA15_RS27770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27745"
                     /product="winged helix DNA-binding domain-containing
                     protein"
                     /protein_id="WP_125515467.1"
                     /transl_table=11
                     /translation="MMITAGELNRATLSRQMLLEREPLTVQDGIRRVVALQAQHPASPY
                     LALWNRLTGFAPADLDAAFAGRSVVKATLMRITLHAVHADDYQDFRGAMQPTLYGSRLG
                     SRFAAAGLTPADAEELVPELLAYAARPRTSAEMQAWAEERLGAEKADGAWWGLKAYAPL
                     QHAPTDAPWSFGVRPSFVAAEAGPPPVGRTVEPEALRALILRYLAGFGPASVADVAQFS
                     MVRRAPVRAALHALDGAVETLRGPDGSTLYDLPGAPRPDADAPAPPRLMAMWDSVLLAY
                     ADRGRVIPPAYRPLVIRNNGDVLPTLLVDGHVAGVWRQVDGRVEATAFHPLSPETWDGL
                     AAEARSLAALLAGRDTKVYSRHHYWWAKLPQAEVRSLPL"
     gene            complement(8740..9903)
                     /locus_tag="DMA15_RS27775"
                     /old_locus_tag="DMA15_27750"
     CDS             complement(8740..9903)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240938.1"
                     /locus_tag="DMA15_RS27775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27750"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_125515468.1"
                     /transl_table=11
                     /translation="MTYTEASMDALRRSGDELADATVATLFERGEVGKFNTLMRYVSTA
                     GAPLPDGLPDVAREYLQATSVPPAWVDWGEMEKARLFFIDNNVHVSTALSFASMPACYV
                     VPHVAKLLSTTHGLKYPSKRMAETGQFTVYLMQPDAFEAGSRFIPAAQKVRLLHASIRH
                     HLERENQWDTAALGTPICQEDMIGGQMFFSLLVLDSLHRLGIHMSTEGAEAYYYAWRVV
                     GAMLGIDQDAVPKTLDEAREFLDLYMIRHMGPSEEGTHLTRQLIDLYEEVVPGTFFDPI
                     ISALIRHLVGDTCADWLQVPRTPWDTVVKAVPHLLGVLETIEDRSPLGAWALDRLGHLT
                     AVFELSSLTRGRVMHYAIPEQLKKEYGISNTVPPTHRWTPPAATVSS"
     gene            complement(10001..11056)
                     /locus_tag="DMA15_RS27780"
                     /old_locus_tag="DMA15_27755"
     CDS             complement(10001..11056)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956355.1"
                     /locus_tag="DMA15_RS27780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27755"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_125515469.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-35, bitscore:
                     121.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDRWEPAAFKTRVDEVLRPFVAQEAERFTAIDPALGPVAEQLE
                     AAVTDGKRLRAAFCYWGWRAAGQPDSDALMRAAASMELVHAAAVVHDDLIDDSALRHGR
                     PTAHIALRGAVRHRPCAVDAARSLAMLVGDLLMGLAGQLFATSGLPAAYLARARPLWSA
                     LARELIAGECLEILGTGAEPDVTASLKVIRYKTAKYTVEQPLLIGGALAGAGGRLREGY
                     SAYGLPLGEAFQLRDDLLGLFGDPERTGKDNADDVRGHRPTALLAETWRLAGDDEREQL
                     RALLGRHDLDDNGLHAVREVMRRLKTPDRVEDMIALRVEEALDTLHELDIPAHAATALT
                     ALAHSAAARLS"
     misc_feature    complement(10757..10759)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11046..11324)
                     /locus_tag="DMA15_RS27785"
                     /old_locus_tag="DMA15_27760"
     CDS             complement(11046..11324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971253.1"
                     /locus_tag="DMA15_RS27785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27760"
                     /product="polyprenyl synthetase"
                     /protein_id="WP_125518036.1"
                     /transl_table=11
                     /translation="MRETAGRRGGLDEQAVLVAAGLADLAVSMAGTALGAVRGLLRRAD
                     TAELAAEAQDDLMARGRLALDRYAAAPPAHLEILARHALARRAADEH"
     misc_feature    11518..11533
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.31"
                     /tool="antismash"
     misc_feature    complement(11527..11542)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.67"
                     /tool="antismash"
     misc_feature    11528..11541
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.37"
                     /tool="antismash"
     gene            11727..12857
                     /gene="recA"
                     /locus_tag="DMA15_RS27790"
                     /old_locus_tag="DMA15_27765"
     CDS             11727..12857
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /gene="recA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125039.1"
                     /locus_tag="DMA15_RS27790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27765"
                     /product="recombinase RecA"
                     /protein_id="WP_125515470.1"
                     /transl_table=11
                     /translation="MAGTDREKALDAALAQIERQFGKGAVMRMGERPNEPIEVIPTGST
                     ALDVALGVGGIPRGRVVEVYGPESSGKTTLTLHAVANAQRAGGAVAFIDAEHALDPEYA
                     KKLGVDIDNLILSQPDNGEQALEIVDMLVRSGALDLIVIDSVAALVPRAEIEGEMGDSH
                     VGLQARLMSQALRKITSALNQSKTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVR
                     LDIRRIETLKDGTDAVGNRTRVKVVKNKVAPPFKQAEFDILYGQGISREGGLIDMGVEN
                     GFVRKAGAWYTYEGDQLGQGKENARNFLKDNPDLANEIERKIKEKLGVGVKAEAPAAEP
                     STDAAGAAAPAEDAAKVVPAPAAAKATKSKAAAAKS"
     gene            12861..13685
                     /gene="recX"
                     /locus_tag="DMA15_RS27795"
                     /old_locus_tag="DMA15_27770"
     CDS             12861..13685
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="recX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142556.1"
                     /locus_tag="DMA15_RS27795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27770"
                     /product="recombination regulator RecX"
                     /protein_id="WP_125515471.1"
                     /transl_table=11
                     /translation="MTRRTDWADHTAPESRPGAAGRGHGGGVDQSGAHQDDGSGFREDG
                     RDSWEGGRSSWEGDGTGSRDGDASREDGTGRSRGRRRRRGGFGDHQDSGPPSSSRAEKG
                     EPPTGDPAERARAICLRLLTGTARTRKQLADALRKREIPDDVAEEVLSRFEEVGLINDG
                     AFADAWVESRHHGRGLARRALARELRTKGVESTLIDEAVGQLDPEQEEATARELVARKL
                     RSTRGLDRDKRVRRLAGMLARKGYGEGMALSVVRQALAEEGEDTEDLGYEAF"
     gene            13830..14615
                     /locus_tag="DMA15_RS27800"
                     /old_locus_tag="DMA15_27775"
     CDS             13830..14615
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016644307.1"
                     /locus_tag="DMA15_RS27800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27775"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_125515472.1"
                     /transl_table=11
                     /translation="MAQEPGTTDAAQAQDSDSGSGSGAGSDTGTAPGRASASATARPPS
                     APPPEELTDLRLLKALAQPRRQQMLQHLTVHGPATSATLARALGLNTGATSYHLRELAR
                     YGFVEEAPGSGHGRERWWRAVPGDRRFPPRSAQSPETRRVMDHLNHLSYAADLDLFERL
                     QREGGAELGEWADAFPCSRGTIRLTLPELREFFEEYIALLNRYKRPAADTPADARTVLT
                     RFLAFPAPVAPIAPAAPIEPDAPAAPASASDNRKETEPS"
     gene            14612..17194
                     /locus_tag="DMA15_RS27805"
                     /old_locus_tag="DMA15_27780"
     CDS             14612..17194
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675413.1"
                     /locus_tag="DMA15_RS27805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27780"
                     /product="ABC transporter permease"
                     /protein_id="WP_125515473.1"
                     /transl_table=11
                     /translation="MMLRYALQTVRDRKGGFLGAFLALMCAAALITACGTLLETGLRGT
                     IKTERYAAAPVIVSADQNVHQTTVKHKKGKTKVKHKAKPIAERAWLSADDIEGRLKKAP
                     GVRAIVPELTFLAQPLTPSAAMDEDRPAYGHAWSSAALTPFRLVDGSAPHAAADLVIDR
                     DLADRAGLKPGDRLTVQSTQSPRSYRVTGIAAPEHGSLAHQTSLFFSSGEAERLAAHPG
                     KVSAFGVIPVRGTEVADLKQAVEHALDGTTAQVNSGDGRGPVEFLDAAGARVKLVSMGG
                     AMGGTSLLVAILVVVGTFALSVQQRHRELALLRAVAATPKQIRKLLGREALLVGAAAGV
                     VGSLAGIPLGGWLHGRFVTAGAISATLERTVSVFPPLAAIGATLLGAWAAARIAGRRIV
                     RIRPAEALAEARVERARPAWSRVVAGLVFLVGGVVLVAVLSVLRTEAASTPVTFLAVVV
                     FACAIALLGPFVVRAAAALLSGPLRLTGPAGKLAHANLRGNAVRMAAVVTPLALLTGMT
                     CTVLFVQPTLGDAARAQARDGIRANWVLAAQGPGVPAQAARDVRTIEGVEAATEVVRTT
                     VRVGLDKYPAQGVTPEGLTRTWDPDVTAGSLKGFDEDSVAVSELAADQLGLKPGSTLKF
                     TLGDGTKARLTVRAVYARGLGFGDLTMAHGLVARHVDNPLAATVLVKSKLKSTPQSDPK
                     SDRTQEQLAAAVAKFPGVRVLDPAVFDGLQAERQQANAEVNHLAMGLVLAFTAIAVVNT
                     LAMSVSERIREFAMLRLAGATRRQVLRMLRTEALAVLLIGAGLGSGVALAVLTAFSVGM
                     TGSAAPAVTPLVYVSVVAVAGVLSLVATALPGRAALRPLPVTVATAKE"
     gene            complement(17266..17667)
                     /locus_tag="DMA15_RS27810"
                     /old_locus_tag="DMA15_27785"
     CDS             complement(17266..17667)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983927.1"
                     /locus_tag="DMA15_RS27810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27785"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_125518037.1"
                     /transl_table=11
                     /translation="MAVSEQPIGIDELLECVRLGLDRVTPQEAYDTSEAGGLLVDIRYA
                     ALRERDGLIPGALVVERNELEWRLDPQGSHRAPEATGHDLRIVVICNEGYASSLAAASL
                     RQLGLRHATDLVGGFQAWRAAGLPVTVTA"
     gene            complement(17658..18200)
                     /locus_tag="DMA15_RS27815"
                     /old_locus_tag="DMA15_27790"
     CDS             complement(17658..18200)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526285.1"
                     /locus_tag="DMA15_RS27815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27790"
                     /product="cysteine dioxygenase"
                     /protein_id="WP_125515474.1"
                     /transl_table=11
                     /translation="MSVSAPSSTAPATARSAPPTAAELLDFVRRSAADPELIASLPLDP
                     EGRTWVRLAGPGGSEAWLIGWPPGSGTGWHDHAESIGAFLTAAGTLKENSLAVRLPTDG
                     WKTLELSEDVDRERELTRGEGRAFGRNHVHEVLNESTTRHAVSVHAYYPPLPRIRRYSR
                     TGEVLRLESVERPEDWQ"
     gene            complement(18779..20482)
                     /locus_tag="DMA15_RS27820"
                     /old_locus_tag="DMA15_27795"
     CDS             complement(18779..20482)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675416.1"
                     /locus_tag="DMA15_RS27820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_27795"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_125515475.1"
                     /transl_table=11
                     /translation="MDPVIVVGAGPVGLALALALARHSVPTVVLDEGPGKDEQRSARTV
                     VLREDTAAFVERLAGHSFGDRESGARWTSWRSLRRKQVMRELSFGEPSCGDVPYDDELL
                     APLHLPQHVLTGALREVIVGERLVKVAVESKLDSLEQDASGLTAHTRGPKDTWWRGSYL
                     VGCDGSRSTVRKLLDIRFPGRTAVERHAVAALRTELPWPGEALLHRMPPWRGGGAEVTG
                     RPLAGGVWRLDWLLPPRGELVTPDALVLRIRETLAGWCGGATPPYELLDTGVHTVHHRL
                     ARRWRVGRAFLAGDAAHLLGALGTQGLDEGLRDADNLAWKLALAWHHGHRDPLLDSYQA
                     ERRAGVAARLRAADQSLPVLRGGKGLRAYVPGSARGHDALLTDGHVGRGLLGAPSSYAH
                     SPLAPAPSQSEIAVGTEPGAPVADVRVTAPDGAFVRLRERLGLGHLLVVLVAPGTVVWE
                     RRHWMTAGIMPRLAAAVTALPHPAELLVAESYPGAPAHCVLLIRPDGHLVTALAGVRPA
                     ELYAAAEAAVGGGTAPEGGHGGDDAEQAGRAVRTGGEESAAGARAGRPSE"
     misc_feature    20534..20552
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    complement(20535..20553)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 21.08"
                     /tool="antismash"
ORIGIN
        1 ggagggagcg ggcgaagggc gagggctcgg gggtggtgac ctcgacgaga cggacgctgc
       61 gggactcgat gtcacccatc agttccgtga ggcccggtac gtcgaagacg tcctggaggc
      121 attccctcac ggcctccagg acgatcggga acgaaccgaa ctcgctcgcc acttcgagca
      181 gctgcgcggc gcgctggcgc tgctgccaca ggggggtgcg cttgccggga ctgcggcgcg
      241 gcagaagcag ggcgcgggcg gcgcactccc ggaagcggga ggcgaaaagg gccgagccgc
      301 ccacctggtc ggtgacgatc tgattgacct cgcccttgtc gaaggcgacg tcacccgcgc
      361 cgatgggggc cttctccgcg tcgtactcca cggcgggccc ggtgggatcg gtggggtcgg
      421 tggaagcctg gtcgagcagg tccaggccca tcaggtcggc gtccggcagg cgcagcacga
      481 tgccgtcgtc cgcgtgcatg acctgcgcgt ccatgccgta ccgctcggtc aggcgggcgc
      541 cgagggcgag ggcccacggg gcgtgcacct gcgctccgaa gggggagtgc acgacgaccc
      601 gccagtcgcc cagctcgtcg cggaaccgct cgaccacgat cgtgcggtcg tccgggatgt
      661 gcccgcacgc ctcgcgctgc tccgcgaggt acgacaggac gttgtcggcg gcccaggagt
      721 cgaggcccgc ggcgagcagc cgcacgcgcg cgtcctcccg cgagagcgcg ccgacctccc
      781 tgaggaaggc gccgagcgcg cggcccagct ccagcgggcg gcccagctgg tcgcccttcc
      841 agaagggcag gcggcccggg acaccggggg cgggggagac cagcacgcgg tcgcgggtga
      901 tgtcctcgat gcgccaggaa ctcgtgccga gcgtgaagac gtcgccgatc cgcgattcgt
      961 acaccatctc ctcgtcgagc tctccgacgc ggccgccgcc cttcttcggg tccgcgcccg
     1021 cgaggaagac cccgaagagg ccgcggtcgg ggatcgtgcc cccggaggtg accgcgaggc
     1081 gctgcgcgcc gggccgcccg gtgaccgtgc ccgcgacgcg gtcccagacc acgcgggggc
     1141 gcagctccgc gaaggcgtcg gagggatagc gcccggcgag catgtccagg acggccgtga
     1201 acgcggactc cgggagcgag gcgaaggagg cggcccggcg caccaccgtg aggaggtcgt
     1261 cgacctgcca ggtgtcgagg gcgaccatcg ccaccagctg ctgcgccagc acgtccaggg
     1321 gattggcggg gacgcgcagt gactcgatgg agccggtccg catccgctct gtgacgacgg
     1381 ccgcctggac gaggtccccg cggtacttgg ggaagacgac tccggtggag accgcgccca
     1441 cctggtggcc cgcacggccc acgcgctgga gcccggaggc gacggacggc ggcgactcga
     1501 cctggacgac caggtcgacc gcgcccatgt cgatgcccag ctccaggctg gaggtggcga
     1561 ccacggccgg cagcctgccc gccttcaggt cctcctcgac ctgggcgcgc tgctccttgg
     1621 agaccgagcc gtggtgggcg cgggccagca gcggcggggc gcccttggcg gcaccggact
     1681 cggccatcag ctccgccggg gagtggtcct cggggagggc ctcgcccgtc gctcgttcgt
     1741 acgcgatctc gttgaggcgg ttgcacaggc gctcggcgag gcggcgggag ttggcgaaga
     1801 cgatcgtcga gcggtgcgcc tggacgaggt cggtgatgcg ctcctccacg tgcggccaga
     1861 tcgacggacg ctcggctgcc gcgcccgtgc cgtctccgga gtcggcgacc ggggagccgc
     1921 ccagctctcc gagatcctcg accgggacga ccaccgaaag gtcgaacacc ttgtcggagg
     1981 ggggctggac gatctccacc ttgcgcttgg gggagagata gcgcgcgacc tcgtccaccg
     2041 gccggaccgt cgccgagagg ccgatgcggc gcgcgggctt cggcagcagc tcgtcgaggc
     2101 gctccaggga cagcgcgaga tgggcgccgc gcttggtgcc cgccacggcg tgcacctcgt
     2161 cgaggatcac cgtctcgatg cccgtgagcg cgtccctcgt ggcggaggtg agcatcagga
     2221 agagcgactc gggggtggtg atcaggatgt ccggcggacg ggtggccagg gcgcgccgct
     2281 cggcgggcgg ggtgtcgccc gaacggatgc cgacgcgcac ctccggctcg ggcatgccga
     2341 ggcgcacggc ctcctgccgg atgccggtca gggggctgcg cagattgcgc tccacgtcga
     2401 ccgcgagggc cttcagcggg gacacgtaca gcacccggca gcgcttcctc gggtccgcgg
     2461 gcggcgggga cgaggccagc tggtcgaggg cggccaggaa cgcggccagg gtcttgccgg
     2521 agcccgtggg cgcgacgacg agcacgtcgg aaccctcggc gatcgcgcgc cacgccccgg
     2581 cctgggcgga ggtgggcgcg gagaaagccc ccgtgaacca gccgcgggtc gcgggggaga
     2641 actcgtcgag ggcgccgtgg gcactggacg cggagctgac catgacccca tcgtgcaccc
     2701 cgccactgac atcggcgtcg acctgcggaa acggtgtcgc gcgcacgtcg cagaatggag
     2761 gcatggcagg ttcggcggag caggcccggc actggcggta cgcggcgctg cccggcgtcg
     2821 acctgctgcg ggcgcgctac atccacaaga cgttcgtgcg gcacacccac gagcatttcg
     2881 tgatcgcggg gatcgccgag ggggtcgacg tcttccgcca cggcggcgcc gaccagcacg
     2941 cggggccggg caccctcgcc ctggtcaacc ccgacacccc gcacacgggc cgggccggtg
     3001 taccggaggg ctggcggtac ggtgccgtct acccggcgcc ggaggtggtc gccggtatcg
     3061 ccgcggagac caccgcgttg cggggtgccc ccgggttcgt ccgcccggtg ctcgacgatc
     3121 cgcacgccgt cgccctcgtc caccgggtgc tgcgcgcggc ggaagagggc aacgcgctcg
     3181 ccgccgacac cctgctgagg gtggcggtga cgcggttgct gcggctgaac ggaggacggt
     3241 tgccgcaacg tgccgtgcgc accgccggtg ccggtaccgc ggcacgcgcg cgtgccgtcc
     3301 tcgaagagcg cctcgcggat ccgccgagct tgtcgcggct cgcggccgac ctctcagtga
     3361 gccccttcgc cttgctgcgc gccttccggg acgcgtacgg catgccgccg cacgcctggc
     3421 tcaccgacgc gcgcgtgcgc cgggcgctgc gtctcctgga cgcgggaaca acgcccgccg
     3481 acgccgccac cgccgtgggc ttcaccgacc agccgcacct cagccggcac ttcacccgga
     3541 tcgtgggcgt gcctccaggg gcgtatcagc gcgagcgcaa gaacgtacaa gaccggtggc
     3601 ggcagcgctc gtagggtcca gggcgtggag aacaggtgac gcccacgggc acggacgacg
     3661 gaaccaacga ggggagcagg ggcggcgacg gcggagcagg gggagcgcac gcgcgggacg
     3721 ggcgggcccc gagcaagcgc gacgcgaccg tcgtccgcga cgccctgggc gtcggggtcg
     3781 ccgtcggact ctccggcttc gccttcggag tgacctcggc gggcagcggc ctcaccgtgc
     3841 tccagagctg tctgctcagc ctgctggtct tcaccggagc ctcgcagttc gcccttgtcg
     3901 gggcgctcgc gggtggcggc aaccccttca ccgccgccgc gggcgccttc ttcctcggcg
     3961 tgcgcaacgc cttctacggg ctgcgtctgt cgcagctgct cgccctcccg cgcgcggtgc
     4021 ggccgctcgc cgcgcactgg gtcatcgacg agaccgcggc cgtctccctg gcgcagccca
     4081 cgcggcgagc cgcccgcatc ggcttcacgg tcaccggact gagcctctac gtcctgtgga
     4141 acgccaccac gctgctgggc gcgctggggg cggaggcgat cggcgacacc gacgtgtggg
     4201 gtctggacgc ggcggggccc gctgtcttcc tggcgctgct cgcgcccatg ctgcgtacgg
     4261 cggcggaccg ctccgtcgcc gccgtcgcgg tcgttctggg gctcggactg ctgcccttcc
     4321 tgccgaccgg agcgccggtt ctggtgtccg ctctcgcggt gccgatcgtc ctctccgtag
     4381 agggccgaaa actccgggcg gggcgcaagc acgaagaggg ccatgacatg cacgaagagg
     4441 gccgtgacat gcacgaagag ggtggcgaca tgcacgaaga gggcccagag gaacctgacg
     4501 tcccgcggag ggaggacccg tgagcatctg gatcgcgatc ggcgtgaccg tcgtcggctg
     4561 ttacgtcgtc aaactcgtcg gcctcctggt gcccgcgggc gccttggaaa ggccactcgt
     4621 caagcgggtg gcggccctgg tccccgtggc cctgctggcg gctctcaccg cccagcagac
     4681 cttcgccgaa ggccgggtgc tcctcctgga cgccagggcg gcagggctcg ccgcggccgc
     4741 cctggcgctg ctcctgcgcg ccccgttcct cgtcgtcatc ggcacggcag tgatcgtcac
     4801 ggccgggctg cgggcgctga caggctgacg gaaaggccgt cagccgatgg gccgcccgta
     4861 cgcccgtagc gtgcgcagcg cctcaatggt cacgatcgga cgcgactcca gggccgtgcc
     4921 cggcgcccac tgccgccacc ggacgggcca gccgccgtcc tcctgctgtt ctgccgccaa
     4981 gaagtccagc gagcgttcca tctcggcatc ggtgaaccac tcgcgcgcga gcgaatcggg
     5041 ggccttggcg aagtcgtgcg cgaaatggtg ctcgcccggc gcgtaccccg gcgacaccgg
     5101 atacgcgtcc agatcgtccg ggtccagggc cgcgaggcgc tgctcgcgca cgaggcggcc
     5161 gagacggtcg gccgtggccc gcgcgcgcga gcggtcgggt acgccgtcca ggaaggcgac
     5221 ggccgcctgg atctcgtacg gatgggactt ctcgagcgat tcgacggcgg cccagcagaa
     5281 gtcggtggcc cggaacagcc aggcgtgcca cacctcgttg cggtgcagca gacccaccac
     5341 cggcccggtg gcgagcagct cgccgggcgg gtcgtccacg accggcacga aaggcgccga
     5401 agggtagccg cgctggctgg gatggatcgc ggggagggcg ccctcgggcg tcgacaccga
     5461 cgtcagatag cggcacacgc gctccacccg ctgcccgccg cagcgccgga tcgcgtccag
     5521 gacccgcagc gcgtgcccgg tgtgcagcgg ctggctcacg gggccgcgca gatcgggttc
     5581 gagcgcgtag ccgtacccgc cgtcaggggt gtcgtaggcg gcgagggcgg tctccaccgc
     5641 gtccgccgcc cgacggctct catcgaggaa gtggtacgcg aaccgtcgct gctcgagtac
     5701 gcgcgcggtg agccagacga agtgctcggc gcgggcgacc ggggaggacg cgccatcggg
     5761 ggagggcact gggtcggggg atgctccggt ttcggccatg cttcgaccgt agggcggaaa
     5821 gcgttctcga caagccccct gtgcggggct gcactctcag gggcgcgata ctgaaggcat
     5881 gcggttgacg gtcttctggc agcggatggc ggctcacttc ggagcggggt acgccgactc
     5941 cttcgcgcgc gatcacgtga tggcggaact gggcggccgt acggtccacg aggcactgga
     6001 cgcgggctgg gaggccaagg acgtctggcg cgcggtctgc acggccatgg acgtaccggc
     6061 cgaaaagcgc tgactacgga aggctcgccg ccgtcggagg gcgccacgcg cgcgtgagca
     6121 gtggtgcacg cacgggtagg ccgtgggggt tccgtacgca caggccgtcc caagattgtg
     6181 agcaggccgt cccaagatgc gggggcggcg gcttattgtc ggcggcgtgg gtgagactgg
     6241 gcccgtggca tccacagacg agaccgcgca ggtcacccag gacaacgctc cactcggcac
     6301 gacgccgccc gcgcagcccc ccgccggggc cgaggcagga cgtggcgccc gcatgccgcg
     6361 ctggctgccg cgtgccatgg tgctcgccct cgcgctcatc gcctgcttcc agctgggcag
     6421 ttgggccttc catcagctga ccggactgtt gatcaacgtc ctgatcgcgt tcttcctggc
     6481 gctcgccgtc gagccggcgg tgagctggat ggcggcgcgc gggctgcgca ggggcttcgc
     6541 cacgttcctc gtcttcatgg gcgtcgtgat cgcgagcgcg ggcttcgtca cgatgatggg
     6601 gtcgatgctg gcgggccaga tcgtcgacat ggtcgaggac ttccccgact acctcgacaa
     6661 ggtcatcagc tggatcaacc agacgttcca cacggacctc tcccgcgtcg aggtgcagga
     6721 cagcctggtc cattccgact ggctgcagaa gtacgtgcag aacagcgcca gtggcgtcct
     6781 ggacgtctcc gcgcaggtcc tcggcggcct cttccagctc ctgacgatcc tgctgttctc
     6841 gttctacttc gcggccgacg ggccgcggct gcggcgcgcg ctgtgctcgg tgctgccgcc
     6901 cgccaagcag gccgaggtgc tgcgcgcctg ggagatcgct gtcaacaaga ccggtggcta
     6961 cctctactcg cgcggcctga tggcgctgat ctccggggtc gcccactaca tcctgctcca
     7021 gacgctcgac gtcccctacg cgcccgtgct cgcggtgtgg gtgggcctgg tctcccagtt
     7081 catccccacc atcggcacgt acctggcggg cgccctgccg atgctgatcg ccttcacggt
     7141 cgatccctgg tacgcgctct gggtgctgat cttcgtcgtg atctaccagc agttcgagaa
     7201 ctacgtgctg cagcccaagc tcaccgccaa gagcgtcgac atccaccccg cggtcgcctt
     7261 cggctcggtc atcgccggga cggcgctgct cggggccgtc ggggcgctca tcgccatccc
     7321 tgccatcgcg acccttcagg ccttcctggg ggcgtacgtg aagaggtacg acgtcacgga
     7381 cgacccccgg gtgcacgggc accggcgccg ggtcggaccg accctcctcg cgcgcgtgcg
     7441 gcgcgctctg cgagggccga acaaccccga cgcggccgcg gaggccgaga cacggccgaa
     7501 gcccgacggg cgtctgtagc gcgcaggacg cccccagggc acaggacgga accgcgctca
     7561 cagcggcagc gaccgcacct ccgcctgggg gagcttggcc caccagtagt ggtggcggct
     7621 gtagaccttc gtatcgcggc cggcgaggag cgcggccagg gagcgggcct ccgccgcgag
     7681 tccgtcccag gtctcgggcg acagggggtg gaaggccgtg gcctcgacgc ggccgtccac
     7741 ctgccgccac accccggcga cgtggccgtc caccaggagg gtgggcagca cgtcgccgtt
     7801 gttccggatc accaggggac ggtaggccgg gggtatcacc cgtccgcggt cggcgtaggc
     7861 cagcagcacg ctgtcccaca tcgccatgag ccggggcggg gccggggcgt ccgcgtccgg
     7921 ccgcggggcg ccagggaggt cgtacagcgt gctgccgtcc ggcccccgga gagtctcgac
     7981 agcgccgtcc agggcgtgca gcgccgcgcg tacgggagcc cgccgcacca tggagaactg
     8041 agccacgtcc gccacggagg cggggccgaa ccccgccaga tagcgcagga tcagggcccg
     8101 cagcgcctca ggctccaccg tccgccccac gggcggcgga ccggcctctg ccgccacgaa
     8161 ggacggccgt acgccgaacg accagggcgc gtcggtcggg gcgtgctgga ggggtgcgta
     8221 cgccttcagg ccccaccacg ccccgtccgc cttctcggca ccgagccgct cctcggccca
     8281 cgcctgcatc tcggccgagg ttcttgggcg ggcggcgtag gccagcagct ccggaaccag
     8341 ctcctcggcg tccgcgggcg tcaggcccgc ggcggcgaag cgggaaccga gccgggagcc
     8401 gtacagggtc ggctgcatcg ccccgcggaa gtcctggtag tcgtcggcgt gtacggcgtg
     8461 cagggtgatc cgcatcaaag tcgccttgac caccgagcgc cccgcgaagg cggcgtcgag
     8521 gtcggccgga gcgaagcctg tgagccggtt ccagagggcg aggtacggcg aggccgggtg
     8581 ctgcgcctgg agcgcgacca cgcgtcgtat cccgtcctgg acggtcagcg gttcacgctc
     8641 cagcagcatc tggcggctga gggtggcccg gttgagttct cccgcggtga tcatcacagc
     8701 ggggattgtg cctcgccctt cgcacttcga gcagggggat cagctggaaa cggtggcggc
     8761 gggcggagtc catcgatggg tcgggggcac tgtgttcgag atgccgtact ccttcttgag
     8821 ctgctcgggg atggcgtagt gcatcacgcg tccgcgcgtg agggacgaca gctcgaagac
     8881 ggcggtgagg tggccgaggc ggtccagggc ccaggcgccg aggggtgagc ggtcctcgat
     8941 ggtctccagg acgcccagga ggtgggggac ggccttgacg acggtgtccc agggggtgcg
     9001 gggcacctgg agccagtcgg cgcacgtgtc gccgaccagg tggcggatga gggcggagat
     9061 gatcgggtcg aagaaggtgc cgggcacgac ctcttcgtag aggtcgatga gttgccgggt
     9121 gaggtgcgtt ccctcttcgg aaggccccat gtgccggatc atgtacaggt cgaggaactc
     9181 gcgggcctcg tcgagcgtct tggggacggc gtcctggtcg atgccgagca tggcgccgac
     9241 cacgcgccag gcgtagtagt aggcctccgc gccttccgtc gacatgtgga tgccgaggcg
     9301 gtgcaggctg tccagcacga gcagggagaa gaacatctgc ccgccgatca tgtcctcctg
     9361 acagatcggc gtgccgagcg cggcggtgtc ccactggttc tcgcgttcga ggtggtggcg
     9421 gatggaggcg tgcaggaggc ggaccttctg ggcggcgggg atgaagcggc tgccggcctc
     9481 gaaggcgtcg ggctgcatca ggtagacggt gaactgtccg gtctcggcca tccgtttgga
     9541 ggggtacttc agcccatggg tcgtcgacag gagcttcgcc acgtgcggga ctacgtagca
     9601 ggcgggcatg gaggcgaagg acagcgcggt ggagacgtgc acgttgttgt cgatgaagaa
     9661 cagccgagcc ttctccatct ccccccagtc gacccaggcc ggcgggacac tcgtggcctg
     9721 gaggtactcc cgggcgacat cgggcaatcc gtccggcagt ggagcgcccg ctgtggagac
     9781 gtagcgcatc agggtgttga acttgcccac ctccccgcgt tcgaagaggg tggcgacggt
     9841 ggcgtcggcg agttcgtcac cgctccgtcg cagggcgtcc atcgaggcct cggtgtaggt
     9901 catggcaaag ctccttgtca tccacgccgg gtggcgcacg acaggcgggg gagggtccgg
     9961 ccgaagaggg tgcacgcttg tgccgcccgg ggcgcgaggg tcaggacagg cgggccgccg
    10021 cagagtgcgc cagcgcggtc agggcggtgg cggcatgcgc gggtatatcc agctcatgga
    10081 gggtgtcgag ggcttcctcg acgcgcaggg cgatcatgtc ctcgacgcgg tcgggtgtct
    10141 tcaggcggcg catcacttcg cgcaccgcgt gcaggccgtt gtcgtccagg tcgtgtcggc
    10201 ccaggagggc gcggagctgc tcccgctcgt cgtcaccggc cagccgccag gtctctgcca
    10261 gcagggccgt gggccggtgg ccgcgtacgt cgtcggcgtt gtccttgccg gtgcgttccg
    10321 ggtctccgaa gaggcccagc agatcgtccc tcagctggaa cgcctcgccc aggggcagcc
    10381 cgtaggcgga gtaaccctcg cgcagccgcc cgccggcccc ggccagggcg ccgccgatca
    10441 gcaggggctg ctcgacggtg tacttggcgg tcttgtaccg gatcaccttc agtgacgccg
    10501 tgacgtccgg ctccgctccg gtacccagga tctccaggca ctcgcccgcg atcagctcac
    10561 gggccagcgc cgaccacaac gggcgggccc gggccagata cgcggcgggc agaccgctgg
    10621 tggcgaacag ctgtccggcc agccccatca gcagatcccc caccagcatc gccagcgacc
    10681 tggcggcgtc cacggcgcac gggcgatggc gcaccgcacc gcgcaacgcg atgtgcgcgg
    10741 tgggccggcc gtgccgtaac gcgctgtcgt cgatgaggtc gtcgtgcacg accgcggcgg
    10801 cgtgcaccag ctccatggag gccgccgccc gcatcagagc gtcgctgtcc ggctgccccg
    10861 ccgcacgcca gccccagtag cagaacgccg cccgcagccg cttgccgtcc gtgaccgcgg
    10921 cctccagttg ttcggccacc ggtcccaggg ccgggtcgat cgccgtgaac cgctcggcct
    10981 cctgggccac gaacgggcgc agcacctcgt cgacgcgggt cttgaacgcg gccggctccc
    11041 accggtcagt gctcatcggc ggcccgccga gccagggcgt gccgggcgag gatctccaga
    11101 tgtgccggag gcgcggccgc gtaccggtcc agcgccaatc gcccgcgtgc catcagatca
    11161 tcctgggcct ccgccgccag ttccgcggtg tccgcgcggc gcagcaggcc ccgcaccgcc
    11221 cccagggccg tacccgccat gctcaccgcc agatcggcca gccccgccgc caccaggacc
    11281 gcctgctcgt ccaggccgcc gcgtcgtccc gctgtctccc gcatcacgcc accccacgcc
    11341 agcaccaccg gacggcgccg gtcgcacgcc gttcgtccca gcatcacgac atcccgggca
    11401 cggaagcgga ggaagtcact atcgagtgat cacctcgttc gagcgtacgg atcgctgtgg
    11461 cgggccgggg tggacggcgg gtgcgacggc tgtggcgggt gcggcgtgcc gcgcttgaca
    11521 ctgaaatcga acatctattc ttatggggtg tccggcggtg attttccggg ggtgcgaggg
    11581 gggatccccg ccgcgctccg gaggatttca gtgagggatg gcctcgagtt atccacaggc
    11641 tggacgggcg tcggggcgga ttgtcagtgg caggcgttag cgtctttgac gtgaagcgat
    11701 cgactcaagc aaatcgggtg gaacccatgg caggaaccga ccgcgagaag gcgctcgacg
    11761 ccgcgctcgc acagattgaa cggcaattcg gcaagggcgc agtgatgcgc atgggcgagc
    11821 gtccgaacga gcccatcgag gtcatcccca ccgggtcgac cgcgctcgac gtcgcgctcg
    11881 gcgtcggcgg catcccccgc ggccgtgtgg tggaggtgta cggaccggag tcctccggta
    11941 agacgaccct cacgctgcac gccgtggcca acgcccagcg ggcaggcggc gcggtggcct
    12001 tcatcgacgc cgagcacgcc ctcgaccccg agtacgcgaa gaagctcggc gtcgacatcg
    12061 acaacctcat cctgtcccag ccggacaacg gcgagcaggc tctcgagatc gtcgacatgc
    12121 tggtccgctc cggcgccctc gacctcatcg tcatcgactc cgtcgccgcc ctggtgccgc
    12181 gcgcggagat cgagggcgag atgggcgact cgcacgtggg tctccaggcc cgcctgatga
    12241 gccaggcgct ccggaagatc accagcgcgc tcaaccagtc caagaccacc gcgatcttca
    12301 tcaaccagct ccgcgagaag atcggcgtga tgttcggctc cccggagacc acgaccggtg
    12361 gccgggcgct gaagttctac gcctcggtgc ggctcgacat ccgccgtatc gagaccctga
    12421 aggacggcac cgacgcggtc ggcaaccgca cgcgcgtcaa ggtcgtcaag aacaaggtcg
    12481 cgcccccctt caagcaggcc gagttcgaca tcctctacgg ccagggcatc agccgtgagg
    12541 gcggcctgat cgacatgggc gtggagaacg gcttcgtccg caaggccggc gcctggtaca
    12601 cgtacgaggg cgaccagctc ggccagggca aggagaacgc ccgcaacttc ctgaaggaca
    12661 accccgacct cgccaacgag atcgagagga agatcaagga gaagctgggc gtcggcgtga
    12721 aggccgaggc tccggccgcc gagccgagca cggacgcggc gggcgcggcc gctccggccg
    12781 aggacgccgc caaggtggtg cccgcaccgg ctgccgccaa ggccaccaag tccaaggccg
    12841 cggcggccaa gagctagtcc gtgacgcgac gaaccgactg ggcggaccac accgcccccg
    12901 aaagccgccc cggcgccgcg gggcggggcc acgggggcgg tgtggatcag agcggcgccc
    12961 accaggacga cggcagtggc ttccgggagg acggacgcga ctcctgggag ggcggccgta
    13021 gctcctggga gggcgacggg accggctcgc gggacggtga cgcctcccgc gaggacggca
    13081 ccggccggag ccgcggccgc cgacggcggc gcggcggttt cggcgaccac caggacagcg
    13141 gccccccttc ctcgtcgagg gccgagaagg gggagccgcc gacgggggat ccggctgagc
    13201 gggcgcgggc gatctgtctg cgcctgctca ccggtacggc gcgcacgcgc aagcagctcg
    13261 ccgacgcgct gcgcaagcgg gagatccccg atgacgtggc ggaagaagtc ctctcccgct
    13321 tcgaagaggt cgggctgatc aatgacggcg ccttcgcgga cgcctgggtg gagtcccggc
    13381 accacgggcg gggcctggcc cggcgcgcgc tcgcccggga gctgcgcacc aagggcgtgg
    13441 agtccacgct gatcgacgaa gcggtggggc agctcgaccc ggagcaggag gaggcgaccg
    13501 cgcgcgagct cgtcgcccgc aagctccgct ccacgcgcgg cctcgatcgc gacaagcggg
    13561 tgcgccgcct cgcgggcatg ctcgcccgca agggttacgg ggaaggcatg gcgctcagcg
    13621 tggtccggca ggccctcgcg gaagagggcg aggacacgga ggacttgggg tacgaggcgt
    13681 tctgagcggg ccgctcccac gggggtgggg cggcatccag aacggtccac gtaccccaac
    13741 tcgcgctccg cggggtgggg ttaacccccc tgcggagacg ccggaccacc gcagtgcaca
    13801 ggcatgtgtg cacaggcgac tgtgtacgca tggcacagga acccggcacc actgatgcgg
    13861 cgcaggccca ggactcggac tccggctcgg gctcaggcgc gggctcggac accggcacgg
    13921 ctccggggcg ggcgtcggcg tcggccacag cccggccacc gtccgccccg cctcccgaag
    13981 agctgaccga cctccggctg ctcaaggcgc tcgcgcagcc gcgacggcag cagatgttgc
    14041 agcacctcac cgtgcacggc ccggccacct cggcgacgct ggccagggcc ctcggcctca
    14101 ataccggcgc caccagttac cacctgcgcg agctggcccg ctacggcttc gtcgaggagg
    14161 cgcccggctc cgggcacgga cgcgagcgct ggtggcgggc cgtccccggc gaccggcgct
    14221 ttccgccgcg cagtgcgcag agccctgaga cgcggcgcgt catggaccac ctcaaccacc
    14281 tctcgtacgc cgccgacctc gacctcttcg agcggttgca gcgggagggc ggcgccgaac
    14341 tcggcgagtg ggccgacgcg ttcccctgct cgcgcggcac gatccggctg acccttcccg
    14401 aactccgtga gttcttcgag gagtacatcg cgctgctcaa ccgctacaag cggcccgccg
    14461 cggacacccc ggccgacgcc cgcacggtac tgacccgctt cctggccttc cccgcgcccg
    14521 tcgcgcccat cgcgcccgcc gcacccatcg agccggacgc gcccgccgcg cccgcctccg
    14581 cctccgacaa ccgaaaagag accgagccct catgatgctg cgctacgccc tgcagacggt
    14641 ccgggaccgc aaaggcggat tcctgggcgc cttcctcgcg ctgatgtgtg ccgccgcgct
    14701 catcacggcg tgcggcaccc tcctggagac gggcctgcgc ggcacgatca agaccgagcg
    14761 ttacgccgcc gcgcccgtga tcgtctccgc cgaccagaac gtccaccaga ccacggtcaa
    14821 gcacaagaag ggcaagacca aggtcaagca caaggcgaaa ccgatcgccg agcgggcctg
    14881 gctgtcggcc gacgacatcg agggcaggct caagaaggca ccgggcgtca gagcgatcgt
    14941 gcccgaactg acgttcctcg cccagccgtt gacgcccagc gccgcgatgg acgaggacag
    15001 acccgcgtac ggacatgcct ggagttccgc cgccctgacc cctttccgcc tcgtcgacgg
    15061 cagcgccccg cacgcggccg ctgatctcgt catcgaccgt gatctcgccg accgcgccgg
    15121 gctgaagccc ggtgaccggc tcaccgtcca gtccacgcag agcccgcgca gttaccgcgt
    15181 cacgggcatc gccgctcccg agcacggctc cctcgcccac cagacctcgc tcttcttctc
    15241 ctccggagag gccgagcggc tcgccgcgca ccccggaaag gtcagcgcct tcggcgtcat
    15301 accggtccgg ggcaccgagg tcgccgacct caagcaggcc gtcgagcacg cactcgacgg
    15361 cacgacagcg caggtcaact cgggtgacgg ccgtggcccc gtcgagttcc tggacgcagc
    15421 gggtgcccgc gtcaagctcg tcagcatggg cggcgcgatg ggcggcacct ctctgctcgt
    15481 cgccatcctc gtggtcgtcg gcaccttcgc gctctccgtg cagcagcgcc accgcgagct
    15541 cgccctgctg cgcgccgtcg ccgcgacgcc gaagcagatc cgcaagctgc tcggacgcga
    15601 ggcactgctc gtcggcgccg cggcgggcgt cgtcggctcg ctcgccggga tcccgctcgg
    15661 cggctggctg cacggccggt tcgtgacagc gggggccatc tccgccaccc tcgaacgcac
    15721 cgtcagcgtc ttcccgcccc tcgccgccat cggcgcgacc ctgctcggcg cctgggccgc
    15781 cgcccgcatc gccgggcgcc ggatcgtccg gatccgcccg gccgaggccc tcgccgaggc
    15841 gcgggtcgaa cgggcccggc ccgcctggag ccgtgtggtc gccggtctcg tcttcctcgt
    15901 gggcggcgtc gtcctggtcg ccgtgctcag cgtgctgcgc accgaggccg cttcgactcc
    15961 cgtgacgttc ctggccgtcg tggtcttcgc ctgcgccatc gcgctcctcg gcccgttcgt
    16021 cgtccgggcc gcggccgcgc tgctgagcgg ccccctccgg ctgaccggac cggccggcaa
    16081 gctcgcccac gccaacctgc gcggcaacgc ggtccggatg gccgccgtcg tcacccctct
    16141 cgccctcctc accggcatga cctgcacggt cctcttcgtc cagcccaccc tcggcgacgc
    16201 ggcccgcgcc caggcccgcg acggcatccg cgcgaactgg gtgctcgccg cgcagggccc
    16261 gggcgtcccg gcgcaggccg cgcgggacgt tcgtacgatc gaaggtgtcg aggccgccac
    16321 cgaagtcgtc cgcacgaccg tgcgcgtggg gctcgacaag tacccggcgc agggcgtcac
    16381 tccggaaggc ctcacccgga cctgggaccc ggacgtcacc gcgggatcac tgaagggctt
    16441 cgacgaggac agcgtcgccg tcagcgaact ggccgccgac cagctcgggc tgaagccggg
    16501 cagcacgctc aagttcaccc tcggagacgg tacgaaggcc cggctcaccg tccgtgccgt
    16561 gtacgcccgc gggctcggct tcggcgatct gaccatggcg cacggcctgg tcgcccgcca
    16621 cgtcgacaac ccgctcgccg ccacggtcct cgtcaagagc aagctcaaga gcacccccca
    16681 aagtgatccc aagagcgacc gtacgcaaga acaactcgcg gcggccgtcg cgaagttccc
    16741 gggcgtgagg gtgctggacc cggcagtctt cgacgggctt caggccgagc gacagcaggc
    16801 caacgccgag gtgaaccacc tcgccatggg gctcgtcctg gccttcaccg ccatcgccgt
    16861 cgtcaacacc ctcgcgatgt ccgtgtccga gcgcatccgc gagttcgcga tgctccggct
    16921 cgcgggcgcc acgcgccgcc aggtgctgcg catgctgcgc accgaggcgc tggcggtcct
    16981 gctcatcggc gccgggctcg gcagcggggt ggcgctcgcc gtcctgaccg cgttcagcgt
    17041 cggcatgacg ggcagcgcgg ccccggcggt caccccactg gtgtacgtct ccgtggtcgc
    17101 cgtcgccgga gtgctatccc tggtggcgac cgcgctgccg ggccgcgccg ctctgaggcc
    17161 gctcccggtc accgtggcga cggcgaagga gtaggggagt aaggcgggta aggggcagta
    17221 cgcaagggtg ggcgcccctt accaaaaggg gcgcccaccc tcgcttcacg ccgtgaccgt
    17281 gaccggaagc cccgccgccc gccatgcctg gaagccgccg accaggtcgg tcgcgtggcg
    17341 cagccccaac tgccgcaagg aggcggccgc gaggctcgac gcgtacccct cgttgcagat
    17401 cacgacgatg cgcagatcgt ggccggtggc ctccggggcg cggtggctgc cctgggggtc
    17461 gaggcgccac tccagttcgt tgcgttcgac gacgagcgct ccggggatga gaccgtcgcg
    17521 ctcccgcagt gccgcgtacc ggatgtcgac caggaggccg ccggcctctg aggtgtcgta
    17581 cgcctcctgg ggagtgaccc ggtcgaggcc gagccgtacg cactccagca actcgtcgat
    17641 gccgatcggc tgttcgctca ctgccagtcc tcggggcgct ccacggactc caggcggagc
    17701 acttcgccgg tgcggctgta acggcggatc cgggggagcg gcgggtagta ggcgtgtacg
    17761 gagacggcgt gccgggtcgt cgactcgttc agcacctcgt gcacatggtt gcgcccgaag
    17821 gcgcggccct cgccgcgcgt caactcccgc tcgcggtcga cgtcttcgga gagttccagg
    17881 gtcttccagc cgtcggtggg cagacgcacc gcgagcgagt tctccttgag ggtgcccgcc
    17941 gcggtgagga acgcgccgat cgactccgcg tggtcgtgcc agccggtgcc gctgccgggc
    18001 ggccagccga tcagccaggc ctcgcttccg ccgggccccg cgagccgcac ccacgtacgg
    18061 ccctcggggt cgagcggcag ggaggcgatc agctcggggt cggcggcgct gcggcgcacg
    18121 aagtcgagga gttcggcggc ggtgggaggc gcggagcgcg cggtcgcggg cgcggtggag
    18181 gaaggggcgg aaacagacac gggtaccgtc ctggaggttc gcggaagccg cgcgagcagg
    18241 ccggaaagcg gcgctcagcg cgtggggaaa agatgcgaag tcagcaggac gggtgacaca
    18301 cgcagcctgc gtagcggacg aggtccatgt ggaccctccg ccacaggcgc acatcggtgt
    18361 cggtcacgat ccggagtaga ccatggaggg ggaggacggt caactccggc tcagcatgcg
    18421 gtcgcgcggg gttcagaggg tggtcggagg ggtctcgggg gcgtgacccg aggggcggct
    18481 tgacgtgtct tggagaggcg actggacgtg gcttgggggc ggctggggct ggccccggag
    18541 cgggctgggt gtggcgtgcc cgaggggtct tcggggaggc cccgggagcg cccggggttg
    18601 gcctcagggg cgttatgggt gggcccgagg gacgtctgag gctggccaga gacggccccc
    18661 ccagggacgt ctgaggctgg cccagagacg ccccccaagg acgtctgagg ctggccagag
    18721 acgccgaagt atggcccgag aagcgtcagg gccctgcccc gagaggcccc tcgccccctc
    18781 actccgaagg ccgccccgcc cgcgcccccg cggcgctctc ctccccgccc gtccgaaccg
    18841 cccggcccgc ctgctcggcg tcgtcgcccc cgtgtccgcc ctccggcgcc gtgccgcccc
    18901 ccaccgccgc ctcggccgcc gcgtacagct cggccgggcg cacaccggcg agcgcggtga
    18961 ccaggtgccc gtcgggacgg atgagcagga cgcagtgcgc gggagccccg gggtagctct
    19021 ccgcgacgag cagctcggcg gggtgcggca aggcggtcac ggcggcggcg agccgcggca
    19081 tgatcccggc cgtcatccag tgccgccgct cccacaccac ggtgcccggc gcgaccagga
    19141 cgacgaggag atggccgagc ccgagccgct cccgcagccg gacgaaggcc ccgtcggggg
    19201 cggtcacccg cacgtcggcg accggcgcgc ccggctccgt gcccaccgcg atctccgact
    19261 gggacggcgc gggcgcgagg ggagagtgcg cataggacga cggcgcgccg agcaggccac
    19321 gccccacatg gccgtccgtg agcagcgcgt cgtgcccgcg cgcgctcccc ggcacgtacg
    19381 cgcgcaggcc cttgccgccg cgcagcaccg gcagcgactg gtcggcggcg cgcaggcgtg
    19441 cggctacccc ggcccgccgc tcggcctgat agctgtcgag cagcggatcg cggtgcccgt
    19501 ggtgccaggc gagcgccagc ttccacgcga ggttgtccgc gtcccgaagc ccctcgtcga
    19561 gcccctgggt gccgagcgcg ccgagcagat gcgccgcgtc cccggcgagg aaggcgcggc
    19621 ccacccgcca ccggcgggcg aggcggtggt ggacggtgtg cacgccggtg tcgagcagtt
    19681 cgtacggtgg tgtggcgccc ccgcaccagc ccgcgagggt ctcccggatc cgcaggacga
    19741 gggcgtcggg cgtcaccagc tcgccacgcg gcggaagcag ccagtcgagc cgccacaccc
    19801 cgccggcgag cggacggccc gtcacctcgg cgcccccgcc gcgccacgga ggcatccggt
    19861 gcagcaacgc ttcaccgggc cagggaagtt ccgtgcgcag cgccgccacg gcgtgccgct
    19921 cgacggccgt acgccccggg aagcggatgt cgagcagttt gcgcaccgtc gaacgggacc
    19981 cgtcgcaacc caccagatag ctcccgcgcc accaggtgtc cttcggcccg cgcgtgtggg
    20041 cggtcagccc ggaggcgtcc tgctccaggg agtcgagctt gctctccacc gcgaccttga
    20101 cgagccgctc gccgacgata acctcgcgca gcgcgccggt cagcacatgc tgcggaaggt
    20161 gcagcggggc cagaagttcg tcgtcgtagg ggacatcccc gcaggagggc tccccgaagg
    20221 agagctcccg catcacctgc ttgcgccgca gggaccgcca actggtccag cgggctcctg
    20281 attcccggtc gccgaacgag tgccccgcga gccgctccac gaaggctgcg gtgtcctcgc
    20341 ggagcacgac cgtccgcgcg gaccgctgct cgtccttgcc cggcccttcg tcgaggacga
    20401 ccgtgggcac cgagtggcgg gcgagcgcga gggcgagcgc gaggccgacg gggcccgcgc
    20461 cgacgacgat caccgggtcc acggcgcaca ccctccggcg cgtcgggatc cgtgggtccg
    20521 ggctgcccgg aagcgctgga cgtacctaca ggagctggca gttggagccc ggtgcacgat
    20581 cacagaacgt atgcaaccca ttgccggtgc ttgcgtcaag tgacgatggc agtggcgttc
    20641 accaggaagt aggagcggag cggggtgacg ccagggggat ccggggccag ggagacagat
    20701 gtggggggcg gcaccccggc cgccccccac tcctatgccg acgatttgtc agtcggactt
    20761 tccaaccgag ccgctggggc cggagtccgg gcgccccgga ccatcctcgg gcccgccggg
    20821 acccgcgggc ttcgccggct ccgcggcgac cgtcggaccg agcggcgtgg ccgcgtccag
    20881 cacgccgggg gtctcggcgg gctccgcggc ggcggccacc acgatgccgg tcttggcgcg
    20941 gcgcccgcgc ttctcgatcc aggtggcgag cgaggagagc gccatgcaga gcgcgatgta
    21001 gatggcaccg acgacgacga ccgtctggac gaacgggtac gtgccgttca ccggcg
//
