LOCUS       NZ_CP029617            21068 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5603590
            Orig. end                         :: 5624658
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="18"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(319..332)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.74"
                     /tool="antismash"
     gene            complement(426..683)
                     /locus_tag="DMA15_RS25200"
                     /old_locus_tag="DMA15_25200"
     CDS             complement(426..683)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="DMA15_RS25200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25200"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_016639615.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    complement(698..716)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
     misc_feature    727..742
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(728..739)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    778..793
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.1"
                     /tool="antismash"
     misc_feature    901..910
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            complement(1000..1968)
                     /locus_tag="DMA15_RS25205"
                     /old_locus_tag="DMA15_25205"
     CDS             complement(1000..1968)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="DMA15_RS25205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25205"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_125515038.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLVHALASEMKLDAVTTEYRGHARD
                     LGRQAAESKDIELVVALGGDGTVNEVVNGLLHHGPDPDRLPRLAVVPGGSTNVFARALG
                     LPNDAVEATGALLDALREGSERTVGLGLAGGTPGTEDEAVPSRWFTFCAGLGFDGGVVG
                     RVEQQRELGRRSTHALYVRQVLRQFLDEPHRRRGMITVERPGEDPVTDLVMSIVCNTSP
                     YSYLGNRPLYASPRASFDTGLDVLGLKKLSTAAVARYGTQLLTSTPERGPHGKHAVTLH
                     DLTDFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     gene            2094..2552
                     /locus_tag="DMA15_RS25210"
                     /old_locus_tag="DMA15_25210"
     CDS             2094..2552
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984445.1"
                     /locus_tag="DMA15_RS25210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25210"
                     /product="hypothetical protein"
                     /protein_id="WP_125515039.1"
                     /transl_table=11
                     /translation="MSTERKSTPQAPEPAVSGPRPARLTAAAALAALEGLALLAGGVYM
                     LVMGLAGKPDNPQQAETGGITLIVLALLPLLAARGLLKLRRWSRGPAIITQIMALPVAW
                     QLLQADSAAIPAGIVLAIVAVAALVLLINPATTEALGIRGPGNVPDQR"
     gene            complement(2588..3619)
                     /locus_tag="DMA15_RS25215"
                     /old_locus_tag="DMA15_25215"
     CDS             complement(2588..3619)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="DMA15_RS25215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25215"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_125515040.1"
                     /transl_table=11
                     /translation="MRDGDGPVRDEERGTQSLPADGREGVRPMATGIPEQQAKPHPEDP
                     GQPGPLTVADVSEQAEPTAKDELKRLSGRGGGRRAGNMSEHEHSRHDPQDRSGARAMFI
                     ELRGLDDGSPEYAELRNQLVRMHLPLVEHLARRFRNRGEPLDDLTQVATIGLIKSVDRF
                     DPERGVEFSTYATPTVVGEIKRHFRDKGWAVRVPRRLQELRLALTTATAELSQLHGRSP
                     TVHELAEKLGISEEEVLEGLESANAYSTLSLDVPDTDDESPAVADTLGAEDEALEGVEY
                     RESLKPLLEDLPPREKRILLLRFFGNMTQSQIAQEVGISQMHVSRLLARTLAQLREKLL
                     VEE"
     gene            complement(3616..4029)
                     /locus_tag="DMA15_RS25220"
                     /old_locus_tag="DMA15_25220"
     CDS             complement(3616..4029)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="DMA15_RS25220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25220"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_030780840.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGQVDSTVAEDNTVSISLYKKRGAGPGPA"
     misc_feature    4184..4197
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     misc_feature    complement(4189..4202)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     gene            complement(4277..4537)
                     /locus_tag="DMA15_RS25225"
                     /old_locus_tag="DMA15_25225"
     CDS             complement(4277..4537)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000789.1"
                     /locus_tag="DMA15_RS25225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25225"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_125515041.1"
                     /transl_table=11
                     /translation="MNECPHVAALPHPEVAPLSDTCLECLAAGSHPVQLRLCLECGHVG
                     CCDSSPFQHATAHFKETSHAVMRTFEPGESWRWCFVDGSIV"
     gene            4584..6182
                     /locus_tag="DMA15_RS25230"
                     /old_locus_tag="DMA15_25230"
     CDS             4584..6182
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639610.1"
                     /locus_tag="DMA15_RS25230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25230"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_125515042.1"
                     /transl_table=11
                     /translation="MDVLPLVALIAASAMVAGAARRTPVPAPLLLVGVGLIASYVPGVP
                     DYHLDPHIVLPLILPPLLHTAALESSYLDLRANIRPVALLSVGYVLFATLAVGWLAYLL
                     IPDLPLTAALVLGAVIAPPDAVAATAIARRVGLPSRITTILQGESLVNDATAITAFKVA
                     LAAAVGEGASWTGGVQEFLVAAVGGVGVGLLLMVPIHWLRTHLKEAMLQNTLSLLIPFV
                     AYAAAEQVHASGVLAVVVVALYLGHRSWQVDFETRLQEAAVWKVVAFILESAVFALIGL
                     QLPIVLKGLGEYSVGQAVWYAAGVFVFVVVARFAWSYPATYLPRAVSARIREREKDMDW
                     RRPLIVSWAGMRGVVSLAIAFSIPLVMEDGEPFPARNLVLFLTFTTVIGTLVVQGLSLP
                     WLIRVLKLPGRDAQAQTLAEAQAQNAASQAAEARVEELMRDERNRLPRPLQDRLRTVLE
                     RRRNSVWERLGQPNPVTGESADDTYRRLAREAIAAEREVFVRMRDERRIDDEMMRTLLR
                     KLDLEEAAAYREVED"
     gene            complement(6161..7105)
                     /locus_tag="DMA15_RS25235"
                     /old_locus_tag="DMA15_25235"
     CDS             complement(6161..7105)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966371.1"
                     /locus_tag="DMA15_RS25235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25235"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_125515043.1"
                     /sec_met_domain="PALP (E-value: 2.9e-18, bitscore: 65.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSTPPAGLRPRLPSPLQRVEDDRFDRHGVRLLLKRDDLIHPDLP
                     GNKYRKLVLNLRAAADAGHDTLLTFGGAYSNHLRATAAAGRLLGFATVGVVRGDELAGR
                     PLNPSLARCAADGMRLHFVDRSTYRAKSEPGTLAAILGAAGAESAYVIPEGGSNALAVQ
                     GCTALGEELREHTDVAAVACGTGGTLAGLAAGLGPNRRALGIPVLKGGFLGPEIRALQR
                     ETFGGPTANWSLDDRFHCGGYARTPPELIAFAEDFERRHGPETALSVEHLYVAKLLYAL
                     TALSEEGAFPPGTRLTAVITGSGGTPAQSSTSR"
     gene            complement(7244..7834)
                     /locus_tag="DMA15_RS25240"
                     /old_locus_tag="DMA15_25240"
     CDS             complement(7244..7834)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="DMA15_RS25240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25240"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_125515044.1"
                     /transl_table=11
                     /translation="MAPPMSAGRFLEALRDEGVTVVEVGDWEHHNRNHKGPWGPVHGVM
                     IHHTATSGSERTVEICRDGHPSLPGPLCHGVITKDGCVHLVGYGRANHAGLGDDDVLRA
                     VIGEKGLPPDNESNTDGNRHFYGFECENLGDGEDPWPEVQLDAIERVSAAICRVHGWTE
                     RSVIGHLEWQPGKVDPRGFTMGWLRERVEERLK"
     gene            complement(7974..8210)
                     /locus_tag="DMA15_RS25245"
                     /old_locus_tag="DMA15_25245"
     CDS             complement(7974..8210)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985347.1"
                     /locus_tag="DMA15_RS25245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25245"
                     /product="hypothetical protein"
                     /protein_id="WP_125515045.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQRGLTQGKQKLDEVQEKRAGDALLKKLGAAYYA
                     ERRGTGSPQATQQALESLESHIATHGDAFLHGT"
     gene            8462..9868
                     /locus_tag="DMA15_RS25250"
                     /old_locus_tag="DMA15_25250"
     CDS             8462..9868
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="DMA15_RS25250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25250"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_125515046.1"
                     /transl_table=11
                     /translation="MSVGEEIRAESEKPQQSLGTSAARNLATTTKSAPQMQEISSRWLL
                     RMLPWVQVQGGTYRVNRRLSYSVGDGRVTFVKTGDQVEVIPAELGELPVLRDFDDQEVL
                     AELARRCQQREFAPGEVLTSFGSQADEVFLLAHGRVEKVGTGPYGGDAVLGTLADGSYF
                     GESALLDPEAIWEYTTRAVTACTVLTLPRQDLEQVAERSESLRGHLHRLRSIPPQRTNK
                     YGEASIDLSAGHVGEAVLPGTFVDYESAPREYELSVAQTVLRVHTRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLNNCEYDQRIQPHGGVPSPDDMDELLSRRRGSK
                     LFLAHPRAISAFGRELNKRGLVPETIDIAGNRIPTWRGVPIFPCNKIPVTEARTTSIIC
                     MRTGEEEQGVVGLRQSGIPDEIEPSLSVRFMGISEQAIISYLVSTYYSAAVLVPDALGV
                     LENVEIGRWT"
     gene            10001..11068
                     /locus_tag="DMA15_RS25255"
                     /old_locus_tag="DMA15_25255"
     CDS             10001..11068
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142332.1"
                     /locus_tag="DMA15_RS25255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25255"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_240660261.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.1e-57, bitscore:
                     193.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGMAERAAWPRGPGDGQEAAEVLAAARACVDPELRRAIDSLPSS
                     LRRVARYHFGWEHADGSPAAGNAGKAIRPALVLAAVRALGGEPAVAVRAAAAVELIHNF
                     TLLHDDVIDRDTTRRHRPTAWTVFGDADAILVGDALQALGQRLLAEDPHPGAPAAAARL
                     ARCVVELCAGQHADCAMERRGPDEVTLDECLAMAEAKTGALLGCACALGALYAGGGPEE
                     VDALDGFGREAGLAFQLIDDVIGIWGDPGHTGKPAGADLVARKKSLPVVAALASGTPAA
                     TELAGLYGGPPAESEAELERAAHLVERAGGRDWAQVHAADRMSRAVGQLARAVPDPEAA
                     GGLLALAEFVTRRTH"
     gene            11349..11966
                     /locus_tag="DMA15_RS25260"
                     /old_locus_tag="DMA15_25260"
     CDS             11349..11966
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984436.1"
                     /locus_tag="DMA15_RS25260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25260"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_125515048.1"
                     /transl_table=11
                     /translation="MGVAIRRAGEGDRDAVVRLLDEAFMWDPVSSWVFPDEEHRRRRHA
                     ALMAAFFDLALDEGYIDITEDGAAAALWWSVSASAPGSGDTGDVEADGPALLREAIDPE
                     NVRVELIGRLADEAHPTDRAHQYLHMIAVRPDRQGEGLGTALVTTVLERCDREGLHAYL
                     EASNARSRDLYERLGFAFTGTPLDLPDGPRMWPMWREPRAVA"
     gene            12060..12455
                     /locus_tag="DMA15_RS25265"
     CDS             12060..12455
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480393.1"
                     /locus_tag="DMA15_RS25265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_125515049.1"
                     /transl_table=11
                     /translation="MGSEGPRPGAGPQDEPVCGACGEPVGTVIRRRKVLGVFVPVWRPG
                     PCRNAHCEVRVDDEAEAARAAGRTSGRRFRSRHGRRTVALPDPAGRGAPEAEAEVGPAA
                     PRPVGVEDDEADKDDEHNKADKADKAE"
     misc_feature    12312..12314
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12648..13481
                     /locus_tag="DMA15_RS25270"
                     /old_locus_tag="DMA15_25265"
     CDS             12648..13481
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMA15_RS25270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMA15_25265"
                     /product="hypothetical protein"
                     /protein_id="WP_125515050.1"
                     /transl_table=11
                     /translation="MPRVKSEADFPELPLDKFELSARDSERMQRAQSLVVQRCMRSYGF
                     DDFPRDPGLGVQLSESVNSTVTWVAPYGMLDLGQARRWGYGFDPDAAARALPKGRAPTE
                     REDEVLHGLGAEGGDPMVVRGRKVPEGGCSAEGSRRLMADVSDEERLWGYVPGRVEELD
                     KAVARDQRVRRAFRDWSRCVEGKGFKEYESPADAFRDKAWHVGREDGNTARTRRELETA
                     VADVECNRQLNTAGVWWAVSNEKQRADLRRDKSRYEAVREDQDRLRAAVSKALGE"
     gene            13581..14210
                     /locus_tag="DMA15_RS25275"
                     /old_locus_tag="DMA15_25270"
     CDS             13581..14210
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535441.1"
                     /locus_tag="DMA15_RS25275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25270"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_125515051.1"
                     /sec_met_domain="HAD_2 (E-value: 9.9e-09, bitscore: 34.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSGRAFDAVLSDLDGVIRFYDMAELEQLEASAGLPRGSTAEIA
                     FAPETDLPLMRGEITKEQWIDSIARGLAERVPWECGHALGTTLAETKFRADDAVVGLLR
                     RVRAAGLPVLLVTNATPWLADDLALLGLTGPAGLFDDVISSADLGVTKPDRRIYETAAE
                     RAGTAPGRCLFVDDRQENVDAAEALGMTGLLYREPADLHVVLAPLI"
     gene            complement(14233..16329)
                     /locus_tag="DMA15_RS25280"
                     /old_locus_tag="DMA15_25275"
     CDS             complement(14233..16329)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430685.1"
                     /locus_tag="DMA15_RS25280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25275"
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="WP_125515052.1"
                     /transl_table=11
                     /translation="MHSAAPHTLNLGILAHIDAGKTSLTERLLHAAGVIDEVGRVDDGN
                     TLTDSLALERRRGITIKSAVVSFVIEAPESAGASGDGVTVNLIDTPGHPDFIAEVERVL
                     SVLDGAVLVVSAVEGVQAQTRVLLRTLRRLRVPTLIFVNKADRAGARYDGVLKHIAERL
                     TPDIIPMGTVTRLGTREARFTPFTAGSGSPARPGDGDDFTARLTELLAGHDDALLTAYV
                     DDAASLSYARLRGELARQTGRALVHPVYFGSAVTGVGVRELMDGIRELLPSAVGDAEGP
                     LSGSVFKVERGAAGEKIAYVRVFSGTVRTRDRVDILGGAADSGAHGRREGKVTAVSVFD
                     QGTDERRAEVRAGRIGKLWGLGDVRIGDVIGAPPKGSEPGAHFFAPPTLETVVTPVRPA
                     DRGALHLALTQLAEQDPLIDLRQDAVRREVSVSLYGEVQKEVIQATLAEDFGLDVRFRE
                     TTTICVERLVGTGEAFEVGEQEPNPFLATVGLRVEPAPVGSGVEFRLGVELGSMPYAFF
                     RAVEETVRETLHQGLYGWRVPDCAVTMTRAGYWPRQSHAHGTFDKSMSSTAGDFRNLTP
                     LVLMDALREAGTAVHEPMHRFRLDVPADTVGAVLPALARLRAVPHTPTTSGVSYRLEGD
                     IPAQQVHALEQMLPGLTRGEGELESAFDHYEPVRGAPPKRERTDHDPLNRKDYLLRVVR
                     RTPA"
     gene            complement(16558..16953)
                     /gene="sodN"
                     /locus_tag="DMA15_RS25285"
                     /old_locus_tag="DMA15_25280"
     CDS             complement(16558..16953)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="DMA15_RS25285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25280"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_125515053.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDAQFQTRAIAIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKG
                     SADPATGQKALDYIAQIDKIFWETKKA"
     gene            17099..17533
                     /gene="sodX"
                     /locus_tag="DMA15_RS25290"
                     /old_locus_tag="DMA15_25285"
     CDS             17099..17533
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="DMA15_RS25290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25285"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_164551822.1"
                     /transl_table=11
                     /translation="MPELSQESERGRAVLPWGAAEVTGPSMVPTLYHGDRLLVRWGARV
                     RPGDVVVLRHPFQQDLLVVKRAKERREGGWWVRGDNAFAGGDSTDYGVVPEELVLGRVR
                     LRYRPPASGRRSPVALARWAVSAVRPVLAERSVSRRLRAR"
     gene            complement(17416..18066)
                     /locus_tag="DMA15_RS25295"
                     /old_locus_tag="DMA15_25290"
     CDS             complement(17416..18066)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925775.1"
                     /locus_tag="DMA15_RS25295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25290"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_125515054.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPGRNKDALTSVEAIRELFGPSTQMARR
                     ATDSDVTRFRSVRGRLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDHRDGDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEHGVDRLGLCEAAPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLETERSASTGRTAETAQRASATGERRPDAGGR"
     gene            18158..18943
                     /locus_tag="DMA15_RS25300"
                     /old_locus_tag="DMA15_25295"
     CDS             18158..18943
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645681.1"
                     /locus_tag="DMA15_RS25300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25295"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_125515055.1"
                     /transl_table=11
                     /translation="MTETGTGAETGSGLGTDWRAWQASWDRQQQWYLPDREERFRIMLD
                     MVEAVVGPAPRVLDLACGTGSITDRLLQRFPDATSVGVDLDPALLTIAEGTFAGDDRVT
                     FVTADLLDPDWAAALPHDSYDAVLTATALHWLHSEPLATLYGQLGGLVRDGGVFMNADH
                     MPDPATPRLNAAESAYRHRRMDRAKSEGVLDWKEWWQLAAQDPVLAAPTAKRFEIYGEH
                     ADGDMPSAEWHARALREAGFGEARVVWASPSDAVVMGLK"
     gene            complement(19071..19832)
                     /locus_tag="DMA15_RS25305"
                     /old_locus_tag="DMA15_25300"
     CDS             complement(19071..19832)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973712.1"
                     /locus_tag="DMA15_RS25305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25300"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_125515056.1"
                     /transl_table=11
                     /translation="MTAMVKAEGVHKSFGHVEVLKGIDLEVASGEVFCLIGPSGSGKST
                     FLRCINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPH
                     MTALENVMEAPVQVKGIAKSQARERAGQLLERVGLADKAKNYPSQLSGGQQQRVAIARA
                     LAMDPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMIVVTHEMGFAREVGDNLVFM
                     DGGVVVESGHPRDVLTNPQQERTQSFLSKVL"
     gene            complement(19832..20776)
                     /locus_tag="DMA15_RS25310"
                     /old_locus_tag="DMA15_25305"
     CDS             complement(19832..20776)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645683.1"
                     /locus_tag="DMA15_RS25310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25305"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_125515057.1"
                     /transl_table=11
                     /translation="MTTDISKKGPEDDVPKARQAEAIKAIPVRHFGRYVAAVLAIGVLA
                     SIVYAFSQGDIKWGAIPDNFFDERILKGVRETLLLTFLSMLIGVVGGVILSVMRLSKNP
                     VTSSIAWFYIWFFRGTPVLVQLFVWFNLGFVFDYINLGPVYKDEWSDFMTPFLTALLGL
                     GLNEAAYMAEICRAGLLSVDEGQTEASHALGMSHNKTLRRVVLPQAMRVVVPPTGNEFI
                     NMLKTTSLVAAVQYYELLKYAQDIGTSSGATVETLLLAACWYLIMTSILSVGQYYLERY
                     YARGSSRSLPDTPFQKIKANMLSLSNRGAGGVR"
ORIGIN
        1 cggcacgacc aaggacgcac ggctgctgat caccgtccag gacgacggcg tcggcctgcc
       61 cgacggcttc gacccgcacc gctccggcaa tctgggcctg cagatcgtgc gcaccctggt
      121 ggagggggag ctgggcggca ccttcgacat ggtccgcgcc caggacggcg gcacgcgggt
      181 gatcctcgac gtcccggtca gcggcgacaa gtagcggcgc gggccggaag ggaagcgtcg
      241 cgggcctcaa gagcgcggta gcacagagca cagcgcacag cagtgagccc cggacctctg
      301 tggtccgggg ctcactgctc acgttgcgtt gcgcatcggg ggtactgcgc ggctgcggct
      361 cgggggcggg agatgcgtac tcgctgtacg cgccgccaag ctcaggctcg tggggggcgt
      421 gggcgtcagg cgctggcctg gcgtgcacgg ttgcgagcgg cgcggcgctt cattgcacgg
      481 cgctcgtcct cgctgaggcc accccagacg ccggagtcct ggccggactc gagcgcccac
      541 tgcaggcact gctccatgac ggggcagcgg cggcagacgg ccttggcttc ctcgatctgc
      601 agcagcgcag gaccggtgtt gccgatgggg aagaagagct cggggtcttc ctcgcggcaa
      661 acggcgttgt gacgccagtc catggctgct acctctcctt ggtattacat tcagcttgct
      721 tgtgaatgtg aacgctttca cgaatccccc cgcacgggaa gggccgacgc ccagtcgcct
      781 ggtgtggacc tttggtggag gaggggttct ggctctctgt ggggccgatg ttgcgggccg
      841 tcccgatcgc catgtagaga ttcgcaaacc tcggcggcgg atacaacccc ttcaggaaag
      901 ttttttttga ttcctcagtg tcggctgggt cacagccgta cttccatggg gtggaccctg
      961 gcctaaacgt tcgagtgaaa ggactttagg cccttccact cacacaatca cacgcagtgc
     1021 acggcgaacg cctgtgaacg tcacgctcgt gcgcagtccg aggtggtcgc cgtccatctg
     1081 gagggggagg gggaccttcg aatgcaaggt gaagtcggtg aggtcgtgca gcgtgaccgc
     1141 gtgcttaccg tgcggtccgc gctccggtgt cgaagtgagc agctgagtgc cgtaccgggc
     1201 caccgcggcc gtcgagagct tcttcaggcc gaggacgtcc agacccgtgt cgaaggaggc
     1261 gcgcggtgac gcgtacaggg ggcgattgcc caggtaggag tagggcgagg tgttgcagac
     1321 tatggacatc accaggtccg tcaccgggtc ctcgccgggc cgctccacgg tgatcatgcc
     1381 gcgccgccgg tggggctcgt cgaggaactg gcggagcact tggcgcacat agagggcgtg
     1441 cgtcgagcgc ctgcccagct cccgctgctg ctcgactctg ccgaccacgc ccccgtcgaa
     1501 gccgagaccg gcacagaacg tgaaccagcg cgagggcacc gcctcgtcct ccgtgcccgg
     1561 tgtgccgccc gcgaggccga ggcccaccgt gcgctcgctg ccctcgcgca gggcgtcgag
     1621 aagggcgccg gtggcctcca cggcgtcgtt cggcagcccc agggcgcggg cgaagacgtt
     1681 ggtggagccg ccggggacga cggcgaggcg cgggaggcgg tccgggtcgg ggccgtggtg
     1741 cagcaggccg ttgacgacct cgttgaccgt gccgtcgccg ccgagggcga cgaccagctc
     1801 gatgtccttg ctctccgcgg cctgccggcc caggtctctg gcgtgcccgc ggtactccgt
     1861 ggtgaccgcg tcgagcttca tctcgctcgc cagcgcgtgg accaggacat cacgcgtacg
     1921 cgcactggtg gtggttgccg ccgggttgac cacgagaagt gcacgcatgc gcagcagact
     1981 acctagcggc ctttacctgg cctagaccga ggtcccgggg cgggccgcgg ccggggtgtc
     2041 cggcggcccg gggcaagggg cggcgcgcat ccgcccgcgg ctaccctgct ggggtgagca
     2101 ctgagcggaa atccaccccc caagccccgg aaccggccgt atctggcccg cgtcccgctc
     2161 ggctgaccgc ggccgcggcc cttgccgcgc tggagggcct cgccctgctc gccggaggtg
     2221 tgtacatgct cgtgatgggc ctcgcgggca agcccgacaa tccgcagcag gcggagaccg
     2281 gcggcatcac actgatcgtc ctcgcgctgc tgccactgct ggccgcgcgc gggctgctga
     2341 agctgcgccg gtggagccgc gggcccgcca tcatcaccca gatcatggcg ctgccggtcg
     2401 cctggcagct gctgcaggcc gacagcgcgg cgatcccggc cggcatcgtc ctggcgatcg
     2461 tggcggtggc ggcgctggta ctactgatca atccggcgac gaccgaggcc cttggcatcc
     2521 ggggccccgg caacgtaccg gaccagaggt aaccgctact caccgtagcc gttacccaca
     2581 gtagtcgtta ctcctccacc aggagcttct cgcgcagctg cgcgagcgtg cgggcgagca
     2641 ggcgcgagac gtgcatctgg gagatgccga cctcctgtgc gatctgcgac tgggtcatgt
     2701 tgccgaagaa gcgcaggagc aggatgcgct tctcgcgcgg aggaaggtcc tccaggagtg
     2761 gcttgaggga ttcgcggtac tcgacaccct ccagggcctc gtcctcggcg cccagggtgt
     2821 ccgcgacggc cggggactcg tcgtccgtgt cggggacgtc cagcgagagg gtggagtagg
     2881 cgttggcgga ctccaggccc tccaggacct cctcttcgga gatgcccagc ttctcggcaa
     2941 gctcgtgcac cgtgggggag cggccgtgca gctgggacag ctcggccgtg gccgtcgtca
     3001 gcgccagccg cagctcctgg agacgccggg ggacgcggac cgcccacccc ttgtcgcgga
     3061 agtgccgctt gatctctccc acgaccgtcg gtgtcgcgta cgtggagaac tccacgccgc
     3121 gctccgggtc gaagcggtcc acggacttga tcaggccgat cgtggcgacc tgggtgaggt
     3181 cgtccagggg ctcgccgcgg ttgcggaagc ggcgggccag gtgctcgacg agcggcaggt
     3241 gcatgcggac cagctggttg cgcagctccg cgtactccgg actgccgtcg tcgaggcccc
     3301 gcagctcgat gaacatcgcg cgtgcgccgc tgcggtcctg tggatcgtgt cggctgtgct
     3361 cgtgctcgct catgtttccc gcccgtcgcc cgccgccccg gccggagagc cgcttgagct
     3421 cgtccttggc ggtcggctct gcctgctccg acacatcggc caccgtcagc ggacccggct
     3481 gccccgggtc ctccgggtga ggtttggcct gctgctcggg gatcccggtg gccatgggtc
     3541 gcaccccctc cctgccgtcg gcgggcagac tctgtgtgcc gcgctcttcg tcacgcaccg
     3601 gcccgtcccc gtccctcacg ccggcccggg tcccgcgccg cgcttcttgt agaggctgat
     3661 cgagacggtg ttgtcctcgg cgacggtgga gtccacctgg cccgcgaggg ccgacagcac
     3721 agtccaggcg aaggtgtccc gctccggggc ccggccgtcg gtcgtgggcg ccgagaccgt
     3781 cacctccaac gagtcgtcga cgagccggaa gacgcagctg agcacggagc ccggcacggc
     3841 ctgctggagg aggatcgcgc aggcctcgtc gaccgcgatg cggaggtcct cgatctcgtc
     3901 gagagtgaag tccaaacgcg ccgcgaggcc ggccgtcgcc gtccgcagca ccgacaggta
     3961 ggcacccgca gccggaaggc ggacctccac gaagtcctga ttcccgggct cgcctgcgat
     4021 ctgggacacc ctcacctcca aggtggtaca agcactttcg gggctccaga accgccgtcc
     4081 agcggcggtc cggactgcgt cacacgggta acgcaccacg tagttctgcg gtgacgctat
     4141 cgcgctcccc agctccgtgt cccggggacc ccgccccgtt gctgtcactc atagtaagca
     4201 tatgagtaca cacagtggct aggggtcggg cggacccaat tggaaagaac gggcgtcggg
     4261 ttgacgtacc caggcgtcag acgatcgaac cgtccacaaa gcaccagcgc cagctctcgc
     4321 ccggctcgaa ggtcctcatc actgcgtgtg aggtctcctt gaagtgcgcc gtcgcgtgct
     4381 ggaacggcga ggagtcgcag cagcccacat gaccgcactc cagacacagc cgcagctgga
     4441 cggggtgact gccggccgcc aggcactcga ggcacgtgtc gctcagcggg gccacctcgg
     4501 ggtgcggcag cgctgccacg tgcgggcact cgttcatgat tgccaggtta cgacgggaac
     4561 gcggaaggcg gaggggtctg ccgatggacg tactgcccct ggtggcactg atcgcggcga
     4621 gcgccatggt ggcgggggcc gcgcgcagga cacccgtgcc cgccccgctg ctcctggtcg
     4681 gggtggggct catcgcctcg tacgtccccg gggtgcccga ctaccacctc gacccgcaca
     4741 tcgtgctgcc gctgatcctg cctcccctgc tgcacacggc cgccctggag agctcctacc
     4801 tggacctgcg cgccaacatc aggcccgtcg cgctgctctc ggtcggctac gtcctgttcg
     4861 cgacgctcgc cgtcggctgg ctcgcctatc tgctgatccc cgatctgccg ctgaccgccg
     4921 cgctggtgct cggtgccgtg atcgccccgc cggacgcggt cgcggccacc gccatcgcgc
     4981 gcagggtcgg gctcccctcg cggatcacca ccatcctcca gggcgagtcc ctggtgaacg
     5041 acgcgaccgc gatcaccgcc ttcaaggtgg ccctcgcggc ggcggtcggg gagggcgcga
     5101 gctggacggg cggcgtccag gagttcctgg tggccgccgt cggcggggtc ggcgtcgggc
     5161 tgctcctgat ggtgccgatc cactggctgc gcacccacct caaggaggcg atgctgcaga
     5221 acaccctttc gctgctcatc cccttcgtcg cctacgccgc cgcggaacag gtgcacgcct
     5281 ccggagtgct cgccgtggtc gtcgtcgccc tctacctggg acaccgctcc tggcaggtcg
     5341 acttcgagac gcggctccag gaggccgcgg tgtggaaggt cgtcgcgttc atcctggagt
     5401 cggcggtctt cgcgctcatc gggctgcaac tgcccatcgt gctcaagggg ctcggcgagt
     5461 acagcgtcgg acaggccgtc tggtacgcgg cgggggtctt cgtcttcgtc gtcgtggcgc
     5521 ggttcgcgtg gtcctacccg gccacctatc tgccgcgtgc cgtgtcggcg cggatcaggg
     5581 agcgcgagaa ggacatggac tggcgcaggc ccctgatcgt cagctgggcg gggatgcggg
     5641 gcgtggtctc gctggccatc gccttctcga tcccgctcgt catggaggac ggggagccct
     5701 tccccgcgcg caatcttgtc ctgtttctga ccttcaccac ggtcatcggc acgctcgtcg
     5761 tgcagggtct ctcgctgccg tggctgatcc gtgtcctgaa actgcccggc cgggacgcgc
     5821 aggcgcagac gctcgccgag gcgcaggcgc agaacgccgc ctcgcaggcc gcggaggccc
     5881 gcgtggagga actcatgcgg gacgagcgca accgcctccc acggcccctc caggaccgtc
     5941 tgcgcaccgt cctggagcgg cgccgcaact ccgtgtggga acggctcggc caacccaacc
     6001 cggtgacggg ggagtcggcg gacgacacct accggcggct ggcacgcgag gcgatcgccg
     6061 ccgagcgcga ggtgttcgtg aggatgcggg acgaacggcg catcgacgac gagatgatgc
     6121 ggacgctgct gcgcaagctg gacctggagg aggcggccgc ctaccgggag gtcgaggact
     6181 gagccggcgt cccgccgctg ccggtgatca ccgcggtgag gcgggtgccg ggcgggaagg
     6241 cgccctcttc ggagagggcg gtcagggcgt agagcagctt ggcgacgtag aggtgctcta
     6301 cggagagggc cgtttccggg ccgtggcggc gctcgaagtc ctcggcgaag gcgatgagtt
     6361 cgggtggcgt acgggcgtaa ccgccgcagt ggaaacggtc gtccaggctc cagttggcgg
     6421 tcggcccgcc gaacgtctcg cgttgcaggg cccgtatctc cgggcccagg aagccgccct
     6481 tgaggaccgg tatgccaagg gcccgccggt tcgggccgag ccccgcggcg aggcccgcga
     6541 gcgtgccgcc ggtgccgcag gccacggccg ccacatcggt gtgctcgcgc agctcctcgc
     6601 cgagagccgt acagccctgt acggccaggg cgttgctgcc gccctccggg atcacgtacg
     6661 cgctctccgc gccggccgcg ccaaggatcg ccgccagcgt tccgggctcg ctcttcgcgc
     6721 ggtacgtcga tctgtcgacg aagtgcagtc gcatgccgtc ggccgcgcag cgggccagag
     6781 aggggttgag ggggcgcccg gccagttcgt cgccgcgcac gacaccgacg gtggcgaagc
     6841 cgaggaggcg gcccgcggcg gccgtggcgc gcagatggtt ggagtaggcg ccgccgaagg
     6901 tcagcaaggt gtcgtggccc gcgtcggccg cggcccgcag gttcaggacg agcttgcggt
     6961 acttgttgcc cggcaggtcc gggtggatca ggtcgtcccg cttgagcagc agccgcacgc
     7021 cgtgtcggtc gaaacggtcg tcctctacgc gctgcaacgg cgacgggagc cggggtcgca
     7081 gtccggcggg cggggtggag tgcaccccgc cattgtcccc cgcggcacgc cgtgcggcag
     7141 gggccggttc ggtggaggag cctcgcgccc ggactcatcc cggatcacat gcctctccgg
     7201 gttgttgctc gaggctcgac gttacctgcg gcggacctcg acgctacttg aggcgttcct
     7261 cgacgcgctc ccgcagccag cccatggtga agccgcgcgg gtcgaccttg cccggctgcc
     7321 actccaggtg accgatcacc gagcgctccg tccagccgtg gacgcggcag atcgcggccg
     7381 agacccgctc gatggcgtcc agctggacct cgggccaggg gtcctcgccg tcgccgaggt
     7441 tctcgcactc gaagccgtag aagtggcggt tgccgtcggt gttcgactcg ttgtccggcg
     7501 gcaggccctt ctcgccgatg accgcccgca gcacgtcgtc gtcgcccaga ccggcgtggt
     7561 tggcgcggcc gtagccgacg aggtggacgc agccgtcctt ggtgatgacg ccgtgacaga
     7621 gcgggccggg cagtgacggg tgaccgtcgc ggcagatctc caccgtgcgc tcgctgcccg
     7681 aggtggcggt gtgatggatc atcacgccgt gcacggggcc ccagggcccc ttgtggttgc
     7741 ggttgtggtg ctcccagtcg cctacttcga cgacggtcac gccttcgtct cgcagagcct
     7801 ccaagaagcg acccgcggac atgggtgggg ccatgaccgc ctcctttgcg gggcgcgacg
     7861 gccgccggtc gcgaaccgcc tcatacgccc tgcttgtacc ggaattccgg tgcccggacc
     7921 agtcgttcgg aattcatccg agtgatgttc gggcaccgtg cgagccgatc cggtcaggtg
     7981 ccgtgcaaga aggcgtcgcc gtgcgtcgcg atgtgggact ccagggactc cagggcctgc
     8041 tgggtggcct gcggggagcc ggtgccgcgg cgctccgcgt aatacgcggc gccgagcttc
     8101 ttcaggaggg cgtcgcccgc gcgcttctcc tggacctcgt cgagcttctg cttgccctgc
     8161 gtgaggcccc gctgcgcctg ctctttggcg cgatccagga agcctgccat gtgctgtctc
     8221 ctgccggttg aagccaaggg gtacgggcgg tgccgccccg caaagtcttc aacggccgcg
     8281 gtgatctcgc agttcccggc gctcaagcgg gcgagccggt tgcgccggac gggtggaaac
     8341 ggcccccctg ccccacatac gcgtgatcca ttcccgctcg tttgtgtaat ggcgcggcca
     8401 cgttccgtgc tggaaagctg gcggttgcag atcaccgcag gtactcggga gggcacacgc
     8461 aatgtcggta ggcgaagaga tccgcgcgga gtcggagaag ccgcagcaga gcctcggcac
     8521 atcagccgct cggaatctgg ccaccaccac caagtcggca ccgcagatgc aggagatcag
     8581 ctcgcgctgg ctgctgcgga tgctgccctg ggtgcaggtg cagggcggta cgtaccgggt
     8641 gaaccggagg ctgagctact cggtcggtga cggccgcgtg acctttgtga agacggggga
     8701 ccaggtcgag gtcatccccg cggagctggg cgagctgccg gtgctgcggg acttcgacga
     8761 tcaggaggtg ctggccgagc tggcccggcg gtgccagcag cgggagttcg ccccgggcga
     8821 ggtcctgacc tccttcggca gccaggcgga cgaggtcttc ctgctcgcgc acggccgggt
     8881 ggagaaggtc ggcaccggcc cctacggcgg cgacgcggtg ctcgggacgc tcgccgacgg
     8941 ctcctacttc ggggagtcgg cgctcctcga ccccgaggcc atctgggagt acacgacacg
     9001 cgcggtgacc gcctgtacgg tcctgacgct cccgaggcag gacctcgaac aggtcgccga
     9061 gcgcagcgaa tcactgcgcg gccacctcca ccggctgcgc tccatcccgc cccagcgcac
     9121 caacaagtac ggcgaggcgt ccatcgacct ctcggccgga cacgtcggcg aggcggttct
     9181 gccgggcact ttcgtggact atgaatctgc cccgcgcgag tacgagttga gcgtcgccca
     9241 gaccgtcctg cgcgtccaca cgcgcgtggc cgacctctac aaccagccga tgaaccagac
     9301 ggagcagcag ctgcggctca ccgtcgaggc gctcaaggag cgccaggagc acgagctgat
     9361 caacaaccgc gagttcggac tcctgaacaa ctgcgagtac gaccagcgga tccagcccca
     9421 cgggggtgtg cccagccccg acgacatgga cgaactgctc agccgcaggc gcgggtcgaa
     9481 gctcttcctc gcccacccgc gcgcgatctc cgcgttcggc cgcgagctca acaagcgcgg
     9541 actcgtcccc gagaccatcg acatcgcggg caacaggatc cccacctggc gcggtgtgcc
     9601 gatcttcccg tgcaacaaga tcccggtgac cgaggcccgc acgacgtcca tcatctgtat
     9661 gcgtacgggc gaggaggagc agggcgtcgt cggcctgcgg cagagcggca tcccggacga
     9721 gatcgaaccg agcctgtcgg tgcggttcat gggcatcagc gagcaggcga tcatctcgta
     9781 cctggtctcg acctactact ccgcggccgt gctggtcccg gacgcgctcg gtgtcctgga
     9841 gaacgtcgag atcggccgct ggacatgagc cccggaccgt gtccgtggcc gcggcgcggg
     9901 gtacaccccc tccgtacgcg cccacaggcc caggaagcgc caccgtcccc ctccttttcg
     9961 gggtgagtcc atgacggaca cgacgacgga catggcaggc atggcaggta tggcggagag
    10021 ggcggcatgg ccgcggggtc ccggtgacgg gcaggaggcc gcggaggtcc tggcggcggc
    10081 gcgcgcgtgc gtcgaccccg agctgcgccg ggcgatcgac tcgctgccca gctccctgcg
    10141 cagggtcgcg cgctaccact tcgggtggga acacgccgac ggttcaccgg ccgcggggaa
    10201 cgcggggaag gccatcaggc ccgccctcgt gctcgccgcg gtgcgggcgc tcggcgggga
    10261 gcccgccgtg gccgtgcggg ccgcggcggc cgtggagctg atccacaact tcacgctgct
    10321 gcatgacgac gtcatcgacc gcgacaccac gcgccggcac cggcccaccg cctggaccgt
    10381 gttcggtgac gccgacgcga tcctggtcgg cgacgctctg caggcgctgg ggcagcggct
    10441 gctcgccgag gacccccacc caggggcccc ggcggcggcc gcccggctgg cccgctgtgt
    10501 cgtggagctc tgcgcggggc agcacgcgga ctgcgccatg gagcggcgcg gcccggacga
    10561 ggtgacgctc gacgagtgcc tggcgatggc cgaggccaag accggtgcgc tgctcggctg
    10621 cgcgtgcgcg ctcggtgcgt tgtacgcggg cgggggaccg gaggaggtcg acgcgctcga
    10681 cgggttcggc agggaggccg ggctcgcctt ccagctcatc gacgacgtca tcggcatctg
    10741 gggcgacccc ggtcacacgg gcaaacccgc cggtgccgac ctggtggccc gcaagaagtc
    10801 cctgccggtg gtcgccgcgc tcgcctcggg cacgccggcc gccaccgagc tggccgggct
    10861 gtacggcggg ccgcccgccg agagcgaggc cgagctggag cgtgcggcgc atctggtgga
    10921 gcgggcgggc ggccgcgact gggcgcaggt gcacgcggcc gaccggatgt cacgggcggt
    10981 gggccagctc gccagggccg tcccggatcc ggaggcggcg ggcggactgc tggcgctcgc
    11041 cgagttcgtg acgcggcgca cgcactgagg ggcgcagcgg cgtacgggcg tacgggcgta
    11101 tgacggtcgg ggggtgagga cgggaggccg gggggcctgg aggtgagggg ggcgaggggg
    11161 cgaggtgagg gaagaggggt gaggggaggt gaggccccgc gggcgtcggg attccggcgg
    11221 accgcggggg ccttccgcgc gcgcggagcc gatcacttag gctgcaaccg gcgggcggtc
    11281 gcgtggagtt gagcgcgcgg ggcgccgtgc cgtcggaggc gggcgagtgg tgaggggcgg
    11341 ggcgggctgt gggcgtggcg atccgtaggg ccggggaggg ggaccgggac gccgtggtcc
    11401 ggttgctcga cgaggcgttc atgtgggacc cggtgagcag ctgggtcttc cccgatgagg
    11461 agcaccgtcg gcgcaggcac gcggcgttga tggccgcctt cttcgacctc gcgctcgacg
    11521 agggctacat cgacatcacc gaggacggtg cggccgcggc cctgtggtgg tccgtatccg
    11581 cgtcggcgcc cgggagcgga gacaccgggg atgttgaggc ggatgggccc gcgctgctgc
    11641 gcgaggcgat cgacccggag aacgtgcggg tcgagctgat cggccgattg gcggacgagg
    11701 cccacccgac tgaccgggcg caccagtacc tgcacatgat cgccgtgcgg ccggaccggc
    11761 agggggaggg gctgggcacg gcactggtca ccaccgttct cgaacgctgc gaccgcgagg
    11821 gcctgcacgc ctatctggag gcgagcaacg cgcggagccg cgacctgtac gagcggctgg
    11881 ggttcgcctt cacggggacg ccgctcgatc tgccggacgg cccgcggatg tggccgatgt
    11941 ggcgggagcc ccgggcggtg gcctgaggtg ggcgtggggc cggtccgggg acgggttacg
    12001 ggcagggtgg cggcgtcttc gggctgcccc atcgcgccca ccgggaataa actgtccgca
    12061 tgggcagcga agggccccgg cccggcgccg gcccgcagga cgagccggtc tgcggcgcct
    12121 gcggagagcc ggtcggcacg gtcatccggc ggcgcaaggt gctcggggtg ttcgtgccgg
    12181 tctggcgccc cgggccatgt cgtaacgcac attgcgaagt ccgcgtcgac gacgaggccg
    12241 aagccgcgcg ggccgcaggc cggaccagcg gcaggcgctt ccggtcgcgg cacggcagga
    12301 ggacggtggc gttaccggac ccagcgggtc gcggcgcccc cgaagcggaa gcggaagtgg
    12361 gcccggcggc cccgcgcccg gtcggcgtgg aggacgacga ggctgacaag gacgacgagc
    12421 acaacaaggc cgacaaggcc gacaaggctg aatgagatta cgcgtgcccg ccccatgggt
    12481 cggtcggtgg ctcgcccagg gtgttgggga ggggtgcggt gaaggcgcgg tggggtggac
    12541 tcgccctggc ggggctggtg ttcgcggggc tggtgtgggt ggggtccggg gccggcccgg
    12601 actttctttc ggacgactct gttccggtct atgcgcggga gccgggtgtg ccccgcgtga
    12661 agagcgaggc ggacttcccc gaactgccgc tggacaagtt tgagttgagc gcccgtgaca
    12721 gcgagcgcat gcagcgggcc cagtcgcttg tcgtgcagag atgcatgcgg tcgtacgggt
    12781 tcgatgactt cccccgcgac cccgggctgg gcgtgcagtt gagcgagtcg gtcaacagca
    12841 ccgtgacgtg ggttgccccc tacgggatgc tcgacctcgg ccaggcgcgc cgctgggggt
    12901 acggcttcga ccccgacgcg gccgcgcggg ccctgccgaa ggggcgggcg cccacagagc
    12961 gggaggacga ggtgctgcac ggcctcggcg cggagggcgg cgaccccatg gtggtgcgcg
    13021 gccgcaaggt ccccgaggga ggctgctcgg cggagggctc gcggcggctc atggcggacg
    13081 tatcggacga ggagcgcctg tggggttacg ttcccggacg cgtcgaggag ctggacaagg
    13141 ccgtcgcgag ggaccagcgg gtgcgcaggg ccttccggga ctggtcgcgc tgtgtcgagg
    13201 gcaaggggtt caaggagtac gagagtccgg ccgacgcctt ccgtgacaag gcgtggcacg
    13261 tggggcgcga ggacggcaac acggcacgta cgcggcggga gttggagacg gccgtcgccg
    13321 acgtcgagtg caaccggcag ctgaacaccg ccggggtctg gtgggccgtc agcaacgaga
    13381 agcagcgcgc cgacctgcgc cgcgacaagt cccggtacga ggccgtacgc gaggaccagg
    13441 accggctgcg ggccgccgtc agcaaggccc tcggcgaata gccccccggc cggcaggtcc
    13501 cggcaggccc cggcaggtcc cggggaggcc ccggcaggcc cccggcaggc agtgccgcgg
    13561 tcgcgtgata gacacatgcg atgaccctct ccggccgggc gttcgacgcc gtactgagtg
    13621 acctcgacgg cgtgatccgc ttctacgaca tggcggagct ggagcagctg gaggcctcgg
    13681 ccgggctgcc gcggggcagc accgccgaga tcgccttcgc gcccgagacc gatctgccgc
    13741 tgatgcgcgg cgagatcacc aaggagcagt ggatcgactc gatcgcccgc gggctcgccg
    13801 agcgggtgcc gtgggagtgc gggcacgcgc tcgggaccac cctggcggag accaagttcc
    13861 gggccgacga cgcggtggtc ggactgctcc ggcgggtccg cgcggccggg ctgccggtcc
    13921 tgctggtgac gaacgcgacg ccgtggctgg ccgacgatct ggccctgctc gggctcaccg
    13981 ggcccgccgg gctcttcgac gacgtgatca gcagcgccga cctcggtgtc accaagccgg
    14041 accgccgcat ctacgagacg gcggcggagc gggccggtac cgcccccggc cgctgcctct
    14101 tcgtcgacga ccgccaggag aacgtggacg cggccgaggc gctcggcatg accggcctgc
    14161 tgtaccgcga accggccgac ctgcacgtgg tgttggcccc gctcatctga cctcggtgga
    14221 gaggcccggc cctcacgcgg gcgtcctgcg caccacccgc agcagatagt ccttgcggtt
    14281 gagcggatcg tggtccgtcc gctcgcgctt cgggggagcg ccccgcaccg gctcgtagtg
    14341 gtcgaaggcg gactccagct cgccctcgcc gcgcgtgagt ccgggcagca tctgctccag
    14401 cgcgtggacc tgttgcgccg ggatgtcccc ttccaggcgg tacgagactc cgctcgtcgt
    14461 cggtgtgtgc ggtacggccc gcagccgggc gagggcgggc agcaccgccc cgactgtgtc
    14521 ggcgggcacg tcgagccgga agcggtgcat cggttcgtgc accgccgtgc ccgcctcgcg
    14581 cagcgcgtcc atcaggacca gcggcgtcag attccggaag tcgcccgccg tgctcgacat
    14641 gctcttgtcg aaggtgccgt gggcgtggct ctggcgcggc cagtacccgg cgcgcgtcat
    14701 cgtgacggcg cagtcgggga cgcgccaccc gtacaggccc tggtgcaggg tctcccggac
    14761 ggtctcctcg accgcgcgga agaacgcgta cggcatcgaa cccagctcga cgcccagccg
    14821 gaactccacc ccggagccca ccggcgcggg ctcgacgcgc agcccgaccg tggcgaggaa
    14881 cgggttgggt tcctgctcgc cgacctcgaa cgcctcaccc gtgccgacga gccgctccac
    14941 gcagatcgtc gtcgtctccc ggaagcggac gtcaagcccg aagtcctcgg cgagcgtggc
    15001 ctggatgacc tccttctgta cctccccgta gagcgagacc gacacctcgc gccgtacggc
    15061 gtcctgccgc aggtcgatca acgggtcctg ctcggcgagt tgggtgagcg cgaggtggag
    15121 ggctccccgg tcggcggggc gtaccggcgt gacgaccgtc tccagggtgg gcggcgcgaa
    15181 gaagtgcgcg cccggctcgc tccccttggg cggtgcgccg atcacgtcgc cgatacgtac
    15241 gtcgccgagc ccccacagct tgccgatccg tccggcgcgg acctccgcgc ggcgttcgtc
    15301 ggtgccctgg tcgaagacgc tgacggcggt gaccttcccc tcgcggcggc cgtgggcccc
    15361 gctgtccgcc gcgccgccga ggatgtcgac gcggtcgcgt gtgcggaccg tgcccgagaa
    15421 cacgcgtacg tacgcgatct tctccccggc ggccccgcgc tcgaccttga acacgcttcc
    15481 ggagagcggg ccttcggcgt ccccgacggc cgagggcagc aattcgcgga tgccgtccat
    15541 cagttcgcgg acgccgacgc ccgtcaccgc tgagccgaag tagacggggt gcaccagggc
    15601 gcggccggtc tgccgggcca gctcaccgcg gagacgggcg tacgagaggg acgccgcgtc
    15661 gtcgacgtac gcggtgagga gtgcgtcgtc gtgcccggcg agcagttcgg tgaggcgggc
    15721 ggtgaagtcg tcgccgtcgc ccggccgcgc gggggatccg gaaccggcgg tgaagggggt
    15781 gaagcgggcc tcgcgggtgc cgaggcgcgt gaccgtgccc atcgggatga tgtccggggt
    15841 gaggcgttcc gcgatgtgct tcaggacgcc gtcgtagcgg gcgcccgcgc ggtcggcctt
    15901 gttcacgaag atgagcgtgg ggacgcgcag cctgcgcagg gtgcgcagca ggacgcgggt
    15961 ctgcgcctgg acgccctcca cggcggagac caccagcacg gcgccgtcga gcacgctcag
    16021 gacgcgctcc acctcggcga tgaagtccgg gtggccgggg gtgtcgatga ggttgaccgt
    16081 gacgccgtcg ccactcgccc cggcgctctc gggggcctcg atgacgaagg agacgaccgc
    16141 ggacttgatc gtgatgccgc gccggcgctc cagcgcgagg gagtcggtca gggtgttccc
    16201 gtcgtcgacg cggccgacct cgtcgatgac accggcggcg tgcagcagcc gctcggtcag
    16261 gctcgtctta ccggcgtcga tgtgggccag gatgcccaga ttcagtgtgt gcggagcagc
    16321 agaatgcacg taccgtcatg tcctttgaag agaggtgact tccttcgggg cgggacatga
    16381 acgaacgccg catttccttc tccttggtcg actccgccgg gctctcgccg gctccttcca
    16441 gtgcagcagg cggccggcgg gcccggcaaa cgattaagcg cggggacgcg gcgcggggag
    16501 acgccgaagg ggcccgtccg gtgtgccgga cgggccccca cggggtgctc gcgcagatca
    16561 ggccttcttg gtctcccaga agatcttgtc gatctgggcg atgtagtcca gcgccttctg
    16621 gcccgtggcc gggtcagcgg agcccttggc ggccgagagg gccttgaggg tgtcgttgac
    16681 cagctggtgc agctccgggt acttctcgaa gtgcgggggc ttgaagtagt cgctccagag
    16741 caccgacacg tggtgcttgg cgagctccgc gcgctgctcc ttgatggcga tggcgcgcgt
    16801 ctggaactgc gcgtcgtcgt tggcggccat cttctcctgc acggccttga cggactccgc
    16861 ctcgatgcgg gcctgggccg ggtcgtacac gccgcagggg aggtcgcagt gggcgctgac
    16921 cttcaccttg ggggcgaaca ggcgggaaag catgtggctg tccttcctcg tgatcgtctt
    16981 ctcaggtggg acattactcc gtgagagacc ggttttcgcg agtgccccca tgggcttagg
    17041 acaaaagtcc agggtcggac cgggaccggt ggaggatagg accggggagg tgccggtgat
    17101 gccggagctg tcgcaggaga gcgagcgggg aagggccgtc ctgccgtggg gcgccgcgga
    17161 ggtgacgggc ccttcgatgg tgcccacgct gtaccacggg gaccggctgc tcgtgcggtg
    17221 gggcgcgcgc gtccgcccgg gtgacgtggt ggtcctgcgc catccgttcc agcaggatct
    17281 gctggtcgtc aagcgcgcca aggagcgccg cgagggcggc tggtgggtgc ggggcgacaa
    17341 cgcgttcgcg ggcggcgaca gcacggacta cggcgttgtc cccgaggagc tggtcctggg
    17401 ccgggtccgg ctgcgttacc ggccacccgc gtccgggcgg cgctcgccgg tggcgctggc
    17461 gcgctgggcg gtctccgccg tgcgtcccgt gctcgccgag cgctcggtct ccaggcgctt
    17521 gcgggcgcgg taggcggcca cgttggcgcg ggtcgcgcag cggtccgagc agtagcgccg
    17581 ggagcggttc gtcgatgtgt cgaggtaggc gttgcggcac ggcgccgcct cgcacaggcc
    17641 caggcggtcc acgccgtgct cggtgaggtg gaaggcgagg cccatcgcgg cgatcgccgc
    17701 gtacccggcg gtggcgttcg aggggtggtc cgccaggtgc atgtgccaca gcgggcggcc
    17761 gtcgccgtcg cggtggtcgt ggcccgagat ctgcgggctg acggggaact ccaggagcag
    17821 ggagttcagc aggtcgaccg cgagtgtctc gtcgccgccg tccgccgcct cgaagacggc
    17881 acggagcctg ccccgtacgg accggaagcg ggtgacgtcg gagtccgtcg cgcggcgggc
    17941 catctgcgtg ctcggcccga acagctcccg gatggcttcg accgaggtca gcgcgtcctt
    18001 gttgcggccc ggctcctcgc tgttgaccag acgtacggcg tagtccgagt aataggccag
    18061 ttccacttgt agtccttacg agggcgggct atggtcgtct cgtcggcagg taatagccga
    18121 ttgccgtacc agggtattac ggagtggagg ggttctgatg acggaaacgg ggaccggcgc
    18181 cgagaccggg tccgggctcg gcaccgactg gcgtgcctgg caggccagct gggaccgcca
    18241 gcagcagtgg tacctgccgg accgcgagga gcggttccgg atcatgctcg acatggtcga
    18301 ggccgtggtc ggccccgcgc cccgcgtgct cgatctggcg tgcggtacgg gaagtattac
    18361 ggaccggctg ctccagaggt tcccggacgc caccagtgtc ggcgtcgatc tcgaccccgc
    18421 gctgctcacc atcgccgagg gcaccttcgc cggcgacgac cgcgtcacct tcgtcaccgc
    18481 cgacctgctg gaccccgact gggccgccgc gctgccgcac gactcgtacg acgccgtgct
    18541 caccgcgacc gccctgcact ggctgcacag tgaaccgctc gcgaccctct acggccagct
    18601 cggcgggctc gtccgggacg gcggcgtctt catgaacgcg gaccacatgc ccgatccggc
    18661 cactcctcgg ctgaacgcgg ccgagagcgc gtaccggcac cgccggatgg accgggccaa
    18721 gagcgagggc gtgctggact ggaaggagtg gtggcagctg gccgcgcagg atccggtcct
    18781 ggccgcgccc accgcgaagc ggttcgagat ctacggggag cacgcggacg gggacatgcc
    18841 gtccgccgag tggcatgcgc gggctctgcg ggaggcgggc ttcggggagg cgcgggtcgt
    18901 gtgggcctcg ccgtccgacg cggtggtcat gggtcttaag tagcgggatc tccccgcggg
    18961 ttcggtgggg gctggtcgcg cagttccccg cgccccttaa ggggcgcgcc gaaggggccg
    19021 gtacggattc cgtaccggcc ccttcggcga tcactgagac cagcggagcg ctagagcacc
    19081 ttcgacagga acgactgcgt gcgttcctgt tgggggttgg tcaggacgtc tcgggggtgg
    19141 cccgattcga ccaccacgcc gccgtccatg aagacgaggt tgtcgccgac ctcccgtgcg
    19201 aagcccatct cgtgtgtcac gacgatcatc gtcatgccgg actccgcgag gtcgcgcatc
    19261 acgtcgagga cgtcgccgac cagctcgggg tcgagcgccg acgtcggctc gtcgaacagc
    19321 atcagcttcg ggtccatcgc cagcgcccgc gcgatcgcca cgcgctgctg ctggccaccg
    19381 gagagctgcg aggggtagtt cttcgccttg tcggcgaggc ccacccgttc gagcagctgg
    19441 ccggcgcgct cgcgcgcctg gctcttggcg atgcccttga cctggaccgg cgcctccatg
    19501 acgttctcca gcgccgtcat gtgcgggaag aggttgaagc gctggaagac catgccgatg
    19561 tcccggcgct tgagggcgac ctcgctgtcc ttcagctcgt acagcttgtc tcccttctgc
    19621 cggtagccga ccagctcccc gtcgacgtac agccgaccgg cgttgatctt ctccaggtgg
    19681 ttgatgcagc gcaggaacgt cgacttgccg gaaccggacg ggccgatcag gcagaacacc
    19741 tcgccgctcg cgacctcgag gtcgatgccc ttgaggacct ctacgtgacc gaacgacttg
    19801 tggacgccct cggccttcac catggcggtc atcagcgcac acctcccgcg ccgcggttgc
    19861 tcagcgacag catgttggcc ttgatcttct ggaagggggt gtccggcagg gagcgggacg
    19921 agccgcgggc gtagtaccgc tccaggtagt actggccgac gctgaggatc gacgtcatga
    19981 tcaggtacca gcaggcggcg agcagcagcg tctccacggt cgcgcccgac gaggtgccga
    20041 tgtcctgggc gtacttgagg agttcgtagt actgcacggc ggcgacgagc gaggtcgtct
    20101 tgagcatgtt gatgaactcg ttgcccgtcg gcggcacgac cacgcgcatc gcctgcggca
    20161 gcaccacgcg gcgcagcgtc ttgttgtggc tcatgccgag cgcgtgcgag gcctcggtct
    20221 ggccctcgtc gaccgagagc agaccggcgc ggcagatctc cgccatgtac gcggcctcgt
    20281 tcaggccgag accgagcagc gccgtcagga acggcgtcat gaagtccgac cactcgtcct
    20341 tgtagaccgg accgaggttg atgtagtcga agacgaagcc gaggttgaac cagacgaaga
    20401 gctggaccag gaccggcgta ccgcggaaga accagatgta gaaccaggcg atcgaggagg
    20461 tcaccgggtt cttcgacagg cgcatcacgg acaggatcac gccgcccacg acgccgatga
    20521 gcatcgagag gaaggtgagg agcagcgtct cgcggacacc cttgaggatg cgctcgtcga
    20581 agaagttgtc ggggatcgcg ccccacttga tgtcaccctg cgagaaggcg tagacgatcg
    20641 aggcgaggac gccgatcgcc aggaccgccg cgacgtaccg gccgaagtgc cgcacgggga
    20701 tggccttgat ggcctccgcc tgccgcgcct tcgggacgtc gtcctcgggg cccttcttgg
    20761 agatgtcggt ggtcacgtgc gtggcctttc agcgactgag ggagagcggg tggttacttg
    20821 ccgccgttga tcttggcttc cttgaccgcg ccggcctcga cgccccactt cttgacgatc
    20881 tcttcgtagt cgccgttctg gatgatcgcg tcgagcgcgg ccttgatcgc gtcacgcagc
    20941 ttggggttct tcttggagac cgcgatgccg tacggagccg cctcgacctg ctcgccgacg
    21001 agctggaagt ccttgccgcc gccggaggtc ttcaccgcgt acgcggccac ggggaagtcg
    21061 gaggagcc
//
