LOCUS       NZ_CP029617            21113 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5572220
            Orig. end                         :: 5593333
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21113
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11113](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11113
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(140..1477)
                     /gene="aroA"
                     /locus_tag="DMA15_RS25060"
                     /old_locus_tag="DMA15_25060"
     CDS             complement(140..1477)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984472.1"
                     /locus_tag="DMA15_RS25060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25060"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_125515012.1"
                     /transl_table=11
                     /translation="MTATPAHTALWPAPHASGAVTATVHVPGSKSVTNRALVLAALAAE
                     PGWLRRPLRSRDTLLMAGALRAMGVGIEETVSSSSAVTGGLVSGEAWRVIPSGLHGPAT
                     VDVGNAGTVMRFLPPVAALADGPIRFDGDPRSYERPLTGVIDALRVLGARIDDDGRGAL
                     PLTVHGGGALDGGPVEIDASSSSQFVSALLLSGARFNQGVEVRHVGGPLPSMPHIRMTV
                     DMLRSAGAQVDTPEAGGEPNVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGTVTI
                     PDWPAHTTQPGDALREIFTEMGGSCELTEQGLVFTGSGSIHGLDVDLSEVGELTPGIAA
                     VAALADSPSTLRGVAHLRLHETDRLAALTKEINGLGGDVTETADGLHIRPRRLHGGVFH
                     TYDDHRMATAGAVIGLAVDGVQIENVATTAKTLPDFPELWTGMLGN"
     gene            complement(1543..2265)
                     /locus_tag="DMA15_RS25065"
                     /old_locus_tag="DMA15_25065"
     CDS             complement(1543..2265)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480455.1"
                     /locus_tag="DMA15_RS25065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25065"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_125515013.1"
                     /transl_table=11
                     /translation="MESTANASLAALWDRVFGTQSAPEQWLVIGAGLVALAVVVPPRVW
                     RLARNAITIAHEGGHGLVALLTGRRLDGIRLHSDTSGLTVSRGKPTGIGMILTAAAGYT
                     APPLLGLGGAALLSSGRITALLWIATALLVVMLVMIRNAYGALTVILTGGTFLLVSWLA
                     NTDVQAAFAYAVVWFLLLGGVRPAFELQAKRRHGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCSLMGGARWLLDV"
     gene            2315..3136
                     /locus_tag="DMA15_RS25070"
                     /old_locus_tag="DMA15_25070"
     CDS             2315..3136
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="DMA15_RS25070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25070"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_125515014.1"
                     /transl_table=11
                     /translation="MCGRYASSRGPEDLAGIFEIEKWQPEEGEQLAPDFNVAPTKEVYA
                     VLDRPLKDAADPAPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFAA
                     RRCVLPADGYYEWVTAPEERQLEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDKT
                     LPDEHPLAWWVTCTVITTEAETTPLAVAPEEGPRSLADIHPRMPLMLTPDRWDAWLDPS
                     RTDVEELRPLLEPPPAGLMRAYPVSTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            3138..3800
                     /locus_tag="DMA15_RS25075"
                     /old_locus_tag="DMA15_25075"
     CDS             3138..3800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925898.1"
                     /locus_tag="DMA15_RS25075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25075"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_125515015.1"
                     /transl_table=11
                     /translation="MTHETHPPQSAATQLVETDAGEARITWHPARKPRLLLAVSHGAGG
                     GIEARDLKALAAALPAHGVSVALVEQPWRVAGKKLAPAPKTLDVGWRGIWPALEKKGLP
                     VISGGRSAGARVACRTATDLGAAAVLALSFPLHPPGRPEKSRADELLGAGVPTLVVQGG
                     NDPFGRPAEFPEGTYELVEVPYGDHGFAVPKKADVTQDEAVAVITDAVTRWAGMLDA"
     gene            4033..4707
                     /gene="sigR"
                     /locus_tag="DMA15_RS25080"
                     /old_locus_tag="DMA15_25080"
     CDS             4033..4707
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="DMA15_RS25080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25080"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_030780923.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAERPEEGSETAAERTARFERDALTFLDQMY
                     SAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQRE
                     PQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAVYLA
                     DVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGESNGTKGS
                     GS"
     gene            4704..5024
                     /gene="rsrA"
                     /locus_tag="DMA15_RS25085"
                     /old_locus_tag="DMA15_25085"
     CDS             4704..5024
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480448.1"
                     /locus_tag="DMA15_RS25085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25085"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_125515017.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDHEMPDSDCTKFETHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPIDLRAKVMGRIDLIRSGQAVPDQDVSHDAAPGVTPS
                     EA"
     gene            5190..6509
                     /locus_tag="DMA15_RS25090"
                     /old_locus_tag="DMA15_25090"
     CDS             5190..6509
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657918.1"
                     /locus_tag="DMA15_RS25090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25090"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_125515018.1"
                     /transl_table=11
                     /translation="MRSVPAWARVYILSVALAGAVCAAPALSGHTPWPAVTLLAALYAG
                     CERLTLPRGLTAGTFFPVLLAGVFLLPPAAAALVAVPGALLARVDRGPRRVRRLWRAAQ
                     LALASWAAARVYGALGGPAAGAAPDFPQVLGPAGAAVLAFSVVLTALDGGVLATAERVP
                     VRSAWRGLFARSLAPVAVHGLAGLMMAVLWTSPYGPPAALLVLLPMGVSCWAFAQCHRE
                     RAAHQATIRALVQAVDLKDKYTRGHSERVGRASVMIARELGMDDERVEVLRFAGILHDV
                     GKLGVPTRLLRKDGPLTPQERRVIELHPEYGHEMVRGIGFLGEARAAILHHHERLDGSG
                     YPYGLAGTQIPECARVVAVADAFDAMTSTRSYRRARPVSAALQELARCAGAQFDPVMVS
                     ALARALGRDGWHPGVTSDGPEGGLPARGVPAPAVRGAVPR"
     gene            6599..7843
                     /locus_tag="DMA15_RS25095"
                     /old_locus_tag="DMA15_25095"
     CDS             6599..7843
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535170.1"
                     /locus_tag="DMA15_RS25095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25095"
                     /product="HD domain-containing protein"
                     /protein_id="WP_125517995.1"
                     /transl_table=11
                     /translation="MPTTVAYGLAAVIAVVSLGWTLWYGIAERPVALAFGVMIGLGELA
                     RWGSGRQREPAPLGAAGALAYALLGQNAGTATHHGVPQVIAVVVAAALVGAVPHVALGQ
                     GPTPDQMARRVLTVAFAAVCFQPLYNSGKLKDWAGHGPWYALVIVALLVLTALCDAVLA
                     AAMAHARTRWPFGPLLRDELRAMLGIGSAVCATGAVMALAVAVAGLWALPVFSLPLLLT
                     QLAFRRYAAVRATYRQTIASLARATEIAGYTPQGHAHRVAGLSRAVGRDLGLTGPDLTV
                     LEYAALMHDIGQLSLVDPVPEGATAALPEAQQRRIALLGGAVVRQTGVDSAVAVVVERQ
                     ADPYRDQPLTARIVRTANAYDEMARGEGPSGALGGPLNALERLRLATGHDYQPEVVESL
                     ARVVSRGGLSSPPAG"
     gene            7983..8963
                     /locus_tag="DMA15_RS25100"
                     /old_locus_tag="DMA15_25100"
     CDS             7983..8963
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="DMA15_RS25100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25100"
                     /product="hypothetical protein"
                     /protein_id="WP_125515019.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRSAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGGVAASGEPSGMELGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTAAGHSYPVFDEIELWAPSPVPTWVVLLEAATEDDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     SPGAIWVPERECGIAAPAALVRGLLDSWVADSPDSRDWRDLEEVC"
     gene            9045..9695
                     /gene="def"
                     /locus_tag="DMA15_RS25105"
                     /old_locus_tag="DMA15_25105"
     CDS             9045..9695
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105564.1"
                     /locus_tag="DMA15_RS25105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25105"
                     /product="peptide deformylase"
                     /protein_id="WP_125515020.1"
                     /transl_table=11
                     /translation="MAQDTEQQASGGVLPVDDEGFVIDTEDCEERETAYRERGTSRPIT
                     VVGNPVLHKECKDVTAFDDELAKLVDDMFASQRTAQGVGLAANQIGVDLKVFVYDCMDD
                     QGVRHVGVVCNPVLRELPADRRRLDDSGEGCLSVPTAYVDLARPDYAEVTGQDEKGNPI
                     KVRGGGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAEGTPRYPVVPND"
     misc_feature    9756..9769
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     gene            10001..11113
                     /gene="cyc1"
                     /locus_tag="DMA15_RS25110"
                     /old_locus_tag="DMA15_25110"
     CDS             10001..11113
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984462.1"
                     /locus_tag="DMA15_RS25110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25110"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_125515021.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-61, bitscore: 207.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAYSGSTSQTQPHTQVVSVPPALTVPVIEADFPRRLHPYWPKLQ
                     EKSRSWLREMRLMPPDKVERYADSLCYTDLVAGYYIGAPDELLTAIADLSSWFFAWDDR
                     HDRDSVHGRAAQWRWLCRGLHGALDEPRQYLHHRDPLVAGFADCVRRLYAFLGPSWNAR
                     FARHFHPVIEAYDQEFRNRRSGTVPTVEAYVELRRLTFAHWAWIDLLEPTARHELPRAV
                     RKQPAYRKAALATQDFSAWYNDLCSLPKELAGDELHNLGISLIKHEGMTLEQAVRDVHR
                     RVTQCVADFLEAENEVRLLVDRLSDGTAEGKKLADTVESCVFNMRNWFSSVYWFHHESG
                     RYRVDSWDDRSIPPYVTEDALAENELVGEE"
     gene            11110..12486
                     /locus_tag="DMA15_RS25115"
                     /old_locus_tag="DMA15_25115"
     CDS             11110..12486
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950763.1"
                     /locus_tag="DMA15_RS25115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25115"
                     /product="cytochrome P450"
                     /protein_id="WP_125515022.1"
                     /sec_met_domain="p450 (E-value: 4.2e-73, bitscore: 245.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIESAIPVPAASGPGPLRTPPLVKGGAPLLGHAWNLVRDPLGFL
                     SALRDHGDLVRIRLGPRTAYAVCDPELVGALLKRPEFIVGGPLWETLEVLLGKGVATSN
                     GKLHRRQRRMMQPAFRPERIADYAKVMEEEARATAARWSPGATVDVSAEMFRTAVRIVS
                     RSLLEVESIGEKADRIADSLHTVFQGLYRRMVLSVGPLYRVPTPANRRFESALADLHAL
                     VDEIIAERRAAGPGGPDDLLAELLRATDESGAPIADQEIHDHVVSLVVAGAENVASTLA
                     WTFQLLTEHPEQERRLVEEVNSVVGDRAITFADLGALPHLRNVITEAMRIRPAAWIFTR
                     RSVAGTELGGYRIPAGADIVYSVYAMQRDPRSFERHLEFDPDRWKPERAADVPEFAMMP
                     FSVGNRKCPGDHFSLAELALILGTVVPKWRLAPVAETDAGTRVGITLHPKRLVLRAEPR
                     "
     gene            complement(12550..13572)
                     /locus_tag="DMA15_RS25120"
                     /old_locus_tag="DMA15_25120"
     CDS             complement(12550..13572)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966409.1"
                     /locus_tag="DMA15_RS25120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25120"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_125515023.1"
                     /transl_table=11
                     /translation="MSSTTNSEKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEV
                     DLHSDVTDLAKMTPEEQHLIGRLVAFFATGDSIVSNNLVLTLYKHINSPEARLYLSRQL
                     FEEAVHVQFYLTLLDTYLPDPEDRAAAFDAVEEIPSIREKAQFCFKWMDSVEKLDRLET
                     QADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSF
                     AFDVVDTVRKEEPELFDDALQTQVTDMLKEAVEAELQFARDLCGDGLPGMNTDSMRAYL
                     ECVADQRLQRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGSVSFDDEF
                     "
     gene            complement(13572..15986)
                     /locus_tag="DMA15_RS25125"
                     /old_locus_tag="DMA15_25125"
     CDS             complement(13572..15986)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009307573.1"
                     /locus_tag="DMA15_RS25125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25125"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_125515024.1"
                     /transl_table=11
                     /translation="MTIAPAEPASAPSTPTAQGAEGTDGPGAALLRTLTDLTADLPDAD
                     PGRVAAAALRGRSARADESELRELATEAAAGLISEDPAYSKLAARLLSIGIREEAATQG
                     VHSFTDSVAVGHREGLIADRTASFVTEHAARLDALVEAALADGADFRFEYFGLRTLHSR
                     YLLRHPITRQVIETPQHFMLRVASGLAEDGSERALDEVASLYRLMSRLDYLPSSPTLFN
                     SGTRHPQMSSCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTN
                     GHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTH
                     NLNLAHWIPDEFMRRVAADQDWSLFSPADVPELVDLWGEEFDAAYRAAEAAGLAKKTIP
                     ARDLYGRMMRTLAQTGNGWMTFKDAANRTANQTAEPGHTVHSSNLCTEILEVTDDGETA
                     VCNLGSVNLGAFVDTATRDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNAKWRP
                     VGLGAMGLQDVFFQLKLPFDSPEARALSTRIAERIMLAAYEASADLAERNGPLPAWEKT
                     RTARGVLHPDHYGVELTWPQRWAALRERIAATGMRNSLLLAIAPTATIASIAGVYECIE
                     PQVSNLFKRETLSGEFLQVNAYLVEELKRLGVWDAQTREALREANGSVQGFSWIPEEVR
                     ALYRTAWEIPQRGLIDMAAARTPFLDQAQSLNLFLETPTIGKLSSMYAYAWQQGLKTTY
                     YLRSRPATRIARAAGGSGAAATAPAPVPAQVTAEEAVACSLENPESCEACQ"
     regulatory      complement(16118..16258)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    16158..16173
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.26"
                     /tool="antismash"
     misc_feature    complement(16238..16252)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(16269..16283)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 26.1"
                     /tool="antismash"
     gene            complement(16302..16796)
                     /locus_tag="DMA15_RS25130"
                     /old_locus_tag="DMA15_25130"
     CDS             complement(16302..16796)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980392.1"
                     /locus_tag="DMA15_RS25130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25130"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_125515025.1"
                     /transl_table=11
                     /translation="MDITIREAHPEEYEALGALTAQAYLADGHLDFGEDDPYLAVLRDV
                     PGRAAHAEILVAEAAGKVLGSVTYVPSGGPMADIAGANDAEIRMLATSPEARGRGAGEA
                     LVRECVRRAKEAGRTSLVLSTQTSMHAAHRLYERLGFVRTPERDWRPIETVPLLTYALK
                     L"
     gene            complement(16919..18544)
                     /locus_tag="DMA15_RS25135"
                     /old_locus_tag="DMA15_25135"
     CDS             complement(16919..18544)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="DMA15_RS25135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25135"
                     /product="sodium:solute symporter"
                     /protein_id="WP_125515026.1"
                     /transl_table=11
                     /translation="MNGGVNGVALAVFIFFFIAVTVMGFLAARWRKAETESLDEWGLGG
                     RSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLWS
                     VSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGGP
                     DTNWFIKDLPLLIAFAVLAAYTYSSGLRAPALIAFVKDGLIYLVIVVAIIYIPIKLGGF
                     DDIFAKAGDAFAQTNPATDKPRGALAPAEAGQWTYATLALGSALALFMYPHSITATLSS
                     KSRDVIRRNTTILPLYSLMLGLLALLGFMAIAAGIKVENGQLAIPQLFEDMFPDWFTGV
                     AFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGALA
                     FVLTMDKTVAINFQLLGGIWILQTMPALVGGLFTRWFHRWALLAGWAVGMVYGTLAAYG
                     VASPTQKHFGGSSDTIPGIGEIGYIGLTAFVLNVIVTVVLTFVLKALKAPEGIDETSPG
                     DYTADAGDPGVMEELPKATAGAGH"
     gene            complement(18541..18795)
                     /locus_tag="DMA15_RS25140"
                     /old_locus_tag="DMA15_25140"
     CDS             complement(18541..18795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384611.1"
                     /locus_tag="DMA15_RS25140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25140"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_125515027.1"
                     /transl_table=11
                     /translation="MSDAPEVNRPVVTPVRVVIAACLVAPFVAMLWVGSYAKIEPTFIG
                     IPFFYWYQMLWVLISTLLTMIAYKLWQRDQRARKEGARS"
     gene            complement(18917..19114)
                     /locus_tag="DMA15_RS25145"
                     /old_locus_tag="DMA15_25145"
     CDS             complement(18917..19114)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657905.1"
                     /locus_tag="DMA15_RS25145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_25145"
                     /product="YbdD/YjiX family protein"
                     /protein_id="WP_125515028.1"
                     /transl_table=11
                     /translation="MTWLLRGVRWMRWYVRELTDESAYERYVAHVRKDHPAATVLSRRA
                     FERMRTDRQESDPRQGFRCC"
     misc_feature    19496..19511
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     misc_feature    20366..20381
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.31"
                     /tool="antismash"
ORIGIN
        1 ggaccatgcc ctcggccgcg tcctcgtgct tgggcctgat gtgggtgcgg gggcggttgc
       61 ccttgcggtt ggggcggacg cggatgtcgt cctcgtcggg gttcttgccg tagcggcgca
      121 tggttctcgt ccccgcccgt cagttcccga gcattccggt ccagagctcg gggaagtccg
      181 ggagcgtctt cgccgtcgtc gccacgttct cgatctgtac gccgtccacc gcgaggccga
      241 tgaccgcgcc cgcggtcgcc atgcggtggt cgtcgtaggt gtggaagacg ccgccgtgca
      301 gccggcgcgg acggatgtgc agcccgtcgg cggtctcggt gacgtcaccg ccgagtccgt
      361 tgatctcctt ggtgagcgcg gcgaggcggt ccgtctcgtg cagccgcaga tgggcgacgc
      421 cgcgcagcgt ggagggggag tcggcgaggg cggcgaccgc cgcgatgccg ggggtcagct
      481 cgccgacctc gctgaggtcg acgtcgaggc cgtggatcga gccggagccg gtgaagacca
      541 ggccctgctc ggtcagctcg caggagccgc ccatctccgt gaagatctcg cgcagcgcgt
      601 cgccgggctg cgtggtgtgc gcgggccagt cggggatggt gaccgtgccg ccggtgacca
      661 gggcggcggc gaggaacggc tgggcgttgg agaggtcggg ctcgacggtc aggtcgcggc
      721 cgaggagggc gccgggggtg acccgccaga cgttcggctc gccgcccgcc tccggggtgt
      781 ccacctgcgc accggccgag cggagcatgt cgaccgtcat ccggatgtgc ggcatggagg
      841 gcagcgggcc gcccacgtgc cggacctcca cgccctggtt gaagcgcgcg cccgacagca
      901 gcagggcgct cacgaactgg gaggaggacg aggcgtcgat ctcgaccggg ccaccgtcca
      961 gggcgccgcc gccgtgcacg gtcagcggca gcgcgccgcg gccgtcgtcg tcgatacggg
     1021 cgccgagcac ccgcagggcg tcgatcacac cggtcagggg ccgctcgtac gaacggggat
     1081 cgccgtcgaa gcggatcggg ccgtcggcga gggcggcgac cgggggcagg aagcgcatga
     1141 ccgtgcccgc gttgccgacg tcgaccgtgg ccgggccgtg caggcccgag gggatcacac
     1201 gccaggcctc accggagacg aggccgcccg tgacggcgga gctggaggac accgtctcct
     1261 cgatgccgac gcccatcgca cgcagggcgc ccgccatcag cagggtgtcg cgggagcgca
     1321 gcgggcggcg cagccagccg ggctcggcgg cgagcgcggc aaggacgagc gcgcggttgg
     1381 tgaccgattt cgaaccgggt acgtggaccg tcgcggtgac ggctccgctt gcgtgcgggg
     1441 cgggccagag ggcggtgtgc gccggggttg cggtcatgcc ctcactttag tggctgccgg
     1501 agagcccgct cagacggcga gcggccagcg tgccccgccc gctcagacgt cgaggagcca
     1561 gcgtgccccg cccatcaggg agcagagcga gacggcgtgg aagaggaaga gccacagccc
     1621 ggcgggcacg tgcgtcagcc gcgagagctg gtcggcgtcc gagtcgcccg cgcccccgtg
     1681 cctgcgcttg gcctggagct cgaaggcggg acggacgccg cccaggagca ggaaccacac
     1741 caccgcgtac gcgaacgccg cctggacgtc ggtgttcgcc agccaggaga cgagcaggaa
     1801 ggtgccgccg gtcaggatca ccgtcagggc cccgtacgcg ttgcggatca tcaccagcat
     1861 cacgacgagc agcgcggtgg cgatccacag cagcgcggtg atgcgcccgg aggagagcag
     1921 cgcggcgccg ccgaggccga gcagcggggg agcggtgtag cccgccgccg cggtcaggat
     1981 catgccgatg ccggtgggtt tgccgcgcga gacggtcagg cccgaggtgt cggagtgcag
     2041 ccggatgccg tcgaggcggc gcccggtgag cagggcgacc agaccgtggc cgccctcgtg
     2101 cgcgatggtg atggcgttgc gggccaggcg ccatacgcgg ggcggcacga cgacggcgag
     2161 ggccaccaga ccggcgccga tcaccagcca ctgctcgggc gcggactgcg tgccgaagac
     2221 gcggtcccag agggcggcca ggctggcgtt ggcggtgctt tccattgtcg gaactggctc
     2281 ctctggggga tcgggtcgtg gcagtctggc acgtatgtgc ggacggtatg catcgagtcg
     2341 tgggcccgag gacctcgcgg gcatcttcga gatcgagaag tggcagcccg aggaggggga
     2401 gcagctggcc cccgatttca acgtggcccc caccaaagag gtctacgcgg ttctcgaccg
     2461 tcccctgaaa gacgccgcgg acccggctcc ggttcgccag ctgcgtacgc tcaagtgggg
     2521 cctggtccct tcctggtcca agacgcccga gggcggcgcg cggatgatca acgcccgtgc
     2581 cgagaccgtg cacgagaagc cctcctaccg tcgcgccttc gccgcccgcc gctgcgtgct
     2641 gcccgccgac ggttattacg agtgggtgac cgcgcccgag gagcggcagc tggaggtcga
     2701 gggcaagaag aagcggcccc gcaagcagcc gtacttcgtg acccccgccg acggttccgt
     2761 tttcgccatg gccggcctct atgagttctg gcgggacaag accctgcccg acgagcaccc
     2821 cctcgcctgg tgggtgacct gcacggtgat caccacggag gccgagacca cgccgctggc
     2881 cgtcgccccc gaggagggcc cgcgctcgct cgccgacatc cacccgcgga tgccgctcat
     2941 gctcaccccc gaccgctggg acgcctggct cgacccgtcc cgcacggacg tcgaggagct
     3001 gcgcccgctc ctggagccgc ccccggccgg actgatgcgg gcctaccccg tgtcgacggc
     3061 ggtcagcaac gtacgcaaca acggccccga gctgctcaag gagctggaag gccccgaaga
     3121 gggcacactc ttctgacgtg acgcacgaaa cgcacccgcc ccagagcgcg gccactcagc
     3181 tcgtcgagac cgacgccggt gaggcacgga tcacctggca cccggcgcgg aagccccgcc
     3241 tcctgctcgc cgtcagccac ggcgccggtg gcggcatcga ggcccgcgac ctgaaggccc
     3301 tcgccgccgc gctgcccgcg cacggcgtga gcgtcgccct cgtcgagcag ccctggcggg
     3361 tcgcgggcaa gaagctggcg cccgcgccga agacgctgga cgtgggctgg cggggcatct
     3421 ggcccgcgct ggagaagaag gggctcccgg tgatctccgg cggccgcagc gcgggcgcgc
     3481 gcgtggcctg ccgcaccgcc accgatctcg gcgccgccgc ggtcctcgcg ctctccttcc
     3541 ccctgcaccc cccgggcagg cccgagaagt cccgcgccga cgaactgctc ggcgccgggg
     3601 tgccgaccct ggtcgtacag ggcggcaacg accccttcgg caggcccgcc gagttccccg
     3661 aggggacgta cgaactggtg gaagtgccct acggcgacca tggtttcgcg gtgccgaaga
     3721 aggcggacgt gacccaggac gaggccgtgg cggtcatcac ggacgccgtc acgcgctggg
     3781 cgggaatgtt ggacgcgtga cctctgttgt cgcgaacaga cggtgaacac cgtcgcagac
     3841 gtgttcgtac gagagggagt ccgccgcatg ggttcgacca tctgcccgaa ccgctccagc
     3901 gcctctgacc tggagtggac ggtcttgagc gcacccaaaa acgcaactat tcgggcggcg
     3961 cgtggagcgg atcgtcgtct atcctccgat tcgagtgggg ctgctttcgg cctcgccacg
     4021 tcgttggagg aggtgggtcc ggtcactggg accgacgcag ggaccgagca cggccaggcg
     4081 gagcgccccg aagagggttc tgagacggcc gcggagcgca cggcccgttt cgagcgggac
     4141 gcgctgacgt tcctcgacca gatgtactcc gcggcgctgc gcatgacgcg caatcccgcg
     4201 gacgcggagg acctggtgca ggagacctac gcgaaggcgt acgcgtcgtt ccaccagttc
     4261 cgcgagggca ccaacctcaa ggcgtggctg taccgcatcc tcacgaacac gttcatcaac
     4321 tcctaccgca agaagcagcg tgagccccag cgcagcgccg ccgaggagat cgaggactgg
     4381 cagctcgcgc gcgccgagtc gcacatgtcc accggtctgc gctcggccga gtcgcaggcg
     4441 ctcgaccacc tgcccgactc cgacgtgaag caggcgctcc aggcgatccc cgaggaattc
     4501 cgcatcgccg tctatctggc cgatgtcgag ggctttgcgt acaaggagat cgcggacatt
     4561 atggggacac ccatcggtac ggtgatgtcc cggctgcacc ggggccgacg ccaactgcgc
     4621 ggcatgctgg aggactacgc ccgtgagcgc gggctcgtcc cggcgggtgc cggggagtcg
     4681 aacggaacga aaggctcggg ctcatgagct gcggagagcc gcacgagact gactgcagtg
     4741 aagtcctgga ccacctctat gagttcctgg accacgagat gccggacagt gactgcacca
     4801 agttcgagac gcacttcgag gagtgctcgc cgtgcctgga gaagtacggc ctcgaacagg
     4861 ccgtcaagaa gctggtgaag cgctgctgcg gccaggacga cgtaccgatc gacctgcggg
     4921 ccaaggtcat ggggcgcatc gacctcatcc gctccggaca ggccgtgccc gaccaggacg
     4981 tgtcgcatga cgccgcgccg ggagtgaccc cctcagaggc gtgagcggcg tgaaagcggc
     5041 gtgcgcggcg cgagtggcgt gaaagcggcg ccaaagtgcc ttagcgtcac tcgaatgtgc
     5101 taattccccg ctgtccagtg atgcccgtgg ggcaggcgtt ctactctccg gacctgggtc
     5161 ttgcgacctg gaacggggag gagaactcca tgcggtcggt gccggcgtgg gctcgcgtgt
     5221 acatcctgag cgtcgccctg gccggggccg tctgcgccgc gcccgcgctg agcgggcaca
     5281 ccccctggcc ggccgtcacg ctcctcgccg cgctctacgc cgggtgcgag cggctcaccc
     5341 tcccccgcgg cctcaccgca ggaaccttct tccccgtgct gctcgccggg gtcttcctgc
     5401 tgccgcccgc ggccgccgcc ctcgtcgccg tgccgggcgc gctcctcgcc cgcgtcgacc
     5461 gcgggccccg ccgggtacgc cgtctgtggc gcgccgcgca gctggccctt gcctcctggg
     5521 cggcggcccg ggtctacggg gcgctcggcg ggcccgccgc cggtgccgcg cccgacttcc
     5581 cgcaggtcct ggggcccgcc ggggccgccg tgctcgcctt ctccgtcgtc ctcaccgccc
     5641 tggacggcgg ggtgctcgcg acggccgaga gagtccccgt gcgctccgcg tggcgggggc
     5701 tcttcgcgcg ctccctcgcg cccgtcgcgg tgcacggcct cgccgggctg atgatggcgg
     5761 tcctgtggac cagtccgtac gggcccccgg ccgcgctgct cgtgctgctc ccgatgggcg
     5821 tctcctgctg ggccttcgcg cagtgccacc gcgagcgcgc cgcccaccag gccaccatcc
     5881 gggcgctcgt ccaggccgtc gacctcaagg acaagtacac ccgcgggcac agcgagcggg
     5941 tcggccgggc ctcggtgatg atcgcgcgcg agctgggcat ggacgacgag cgcgtcgagg
     6001 tcctgcggtt cgccgggatc ctgcacgacg tcggcaaact cggcgtcccc acccggctgt
     6061 tgcgcaagga cggccccctc accccgcagg agcggcgcgt catcgagctg caccccgagt
     6121 acgggcacga gatggtgcgc ggcatcggct tcctcggcga ggcgcgggcg gcgatcctgc
     6181 accaccacga gcggctggac ggcagcggat acccctacgg gctcgcgggg acgcagatcc
     6241 cggagtgcgc gcgggtggtg gccgtggccg acgcgttcga cgcgatgacg tccacgcggt
     6301 cctaccggcg ggcgcggccg gtctccgccg ctctccagga gctggctcgg tgtgcggggg
     6361 cgcagttcga tccggtgatg gtctcggcgt tggcgcgtgc gcttggccgg gacgggtggc
     6421 atcccggggt tacctcggat gggcccgaag gtggcttgcc tgctcggggt gtgcctgcac
     6481 ctgcggtgcg gggggcggtg ccgcggtgag ggccaccgtt ccggcacccg gcactgaagg
     6541 ctgtgcccac ccgtcccgcc ctgcgggacg cctgcccaca gcagggacgt cgggacgcct
     6601 gcccacaaca gtcgcctacg gcctcgcggc agtgatcgct gtcgtttctc tcgggtggac
     6661 cctttggtac gggatcgccg agaggcccgt cgcgctggcc ttcggggtga tgatcgggct
     6721 cggggagctg gcccggtggg gcagtgggag gcagcgggag cccgcgccgc tgggggccgc
     6781 gggggccctg gcgtacgcgc tccttgggca gaacgccggt acggccacgc accacggcgt
     6841 gccccaggtg atcgccgtgg tcgtcgcggc cgccctcgtg ggagccgtac cgcacgtggc
     6901 gctcggccag gggcccacac ccgaccagat ggcgcggcgc gtactgaccg tcgcgttcgc
     6961 cgccgtctgc ttccaacccc tctacaactc cggcaagttg aaggactggg caggccacgg
     7021 cccctggtac gcgctggtca tcgtcgccct gctcgtcctc accgcgctct gcgacgccgt
     7081 cctcgccgcc gcgatggccc atgcccgcac ccgctggccg ttcggccccc tgctccgcga
     7141 cgaactgcgg gccatgctcg gcatcggctc cgcggtctgc gcgaccgggg ccgtgatggc
     7201 gctcgcggtc gccgtcgcgg gactctgggc gctgcccgtg ttcagcctcc cgctgctcct
     7261 cacccagctg gccttccggc ggtacgcggc cgtgcgggcc acctaccggc agaccatcgc
     7321 ctcgctggcc agggccaccg agatcgccgg atacaccccg cagggccacg cccaccgcgt
     7381 cgccgggctc agccgggccg tcgggcggga cctcgggctc accggccccg acctcaccgt
     7441 cctcgagtac gcggcgctga tgcacgacat cggccagctg tccctcgtcg accccgtccc
     7501 cgagggcgcc accgccgccc tgccggaggc gcagcagcgc cgaatagccc tgctcggcgg
     7561 cgcggtcgta cggcagaccg gggtggactc cgcggtcgcc gtcgtcgtgg agcgccaggc
     7621 cgacccgtac cgcgatcagc cgctcacggc acgtattgtg cgcaccgcga acgcgtacga
     7681 cgagatggcg cggggagaag gaccctcggg ggccctcggg gggccgctca acgccttgga
     7741 gcggctgcgt ctcgccaccg gccacgacta tcagcccgaa gtcgtggagt ccctggcgag
     7801 ggtggtgtcg cggggtggcc ttagctcgcc cccggctggg taacccatgg gtaatgagcg
     7861 gctgtccgac cgtacgtggt tggatgcgaa gaagagggtg cgcgggggca tcgacccgac
     7921 gccgcgtcct catcagatgg gacttccgac aaatcgtgac aggcgggaat caggcgggaa
     7981 tcgtgaggat cttcggcaag ggacggcacc ggccctccgc ctcatggcgg caggcgaccg
     8041 accgcgcgtt cacgctgatc ggcgacggcc ggtacgagga cgcgggggcg ctgctcacgc
     8101 gtgcggcgga tctggagccg tggctgtccg agtcctggtt caacctcgct ctgctgcaca
     8161 agttccggca cgactgggag caggcgcggg ccgcggggct gcgtgccgtc gcgctcctgg
     8221 accgctcggc gggcgccccg gactggtgga acgtgggcat cgcggcgacc gcgctccagg
     8281 actggccgct ggcccgccgc gcctggcagg cgtacggcct gcgggtgccc ggcggggtgg
     8341 ccgcgtccgg cgagccctcg ggcatggagc tgggcagtgc ggccgtgcgg ctctccccgg
     8401 agggcgaggc cgaggtggtg tggggccgca ggctggatcc cgcgcgcatc gaggtgctgt
     8461 ccatcccgct gccctcctcc gggcgccgct ggggcgaggt cgtgctgcac gacggcgtcc
     8521 cgcacggtga gcggacgacg gcggccggac actcgtatcc cgtcttcgac gagatcgagc
     8581 tgtgggcgcc ctcacccgtg ccgacctggg tggtcctcct ggaggccgcc accgaggacg
     8641 accgggacgc gctggagcag ctcgcggccg acgcgggctt cgccgccgag gactggtcgt
     8701 cctccgtgcg gctgctgtgc cgcatgtgct ccgagtcgcg gatgccgagc gacgagggcg
     8761 acggcgagca ccttgacccg cacgaccaca gcgagccggg ccatccgggc ccgctcggcc
     8821 accgcagccc cggcgcgatc tgggtgccgg agcgggagtg cggcatcgcg gcgccggccg
     8881 ccctggtgcg cgggctcctc gacagctggg tggcggacag cccggactcg cgggactggc
     8941 gggatctgga agaggtctgc tgacccgagg agagcgggcc gtacttcgcc gtaggctgta
     9001 ccggcacaaa ctcttgaggg tttcacggaa ggcttacggc ggacatggcg caggacactg
     9061 agcagcaggc ctccggcggg gtgctccccg tcgacgacga gggcttcgtc atcgacacgg
     9121 aggactgcga ggagcgcgag acggcctatc gcgagcgcgg cacgtcccgc ccgatcacgg
     9181 tcgtcggcaa cccggtcctg cacaaggagt gcaaggacgt caccgccttc gacgacgagc
     9241 tggccaagct ggtcgacgac atgttcgcca gccagcgcac cgcgcagggc gtcggcctcg
     9301 ccgccaacca gatcggcgtc gacctgaagg tcttcgtcta cgactgcatg gacgaccagg
     9361 gcgtgcgcca cgtcggcgtc gtctgcaacc cggtcctgcg cgagctgccc gccgaccggc
     9421 gccgcctcga cgactcgggc gagggctgcc tctccgtccc gaccgcctat gtcgacctgg
     9481 cccgcccgga ctacgccgag gtgaccgggc aggacgagaa gggcaacccc atcaaggtgc
     9541 gcggcggtgg ctacttcgcg cgctgcctcc agcacgagac ggaccacctg tacggctatc
     9601 tgtacatcga ccgcctctcc aagcgggagc gcaaggacgc gctgcgccag atggcggagg
     9661 gcacgccgcg ctaccccgtg gtgcccaacg actgacgcac gcgccgcctg agcggcgcgg
     9721 gaaccgtgtg acaccagcgg cccctgatcg ggaacttgac cccgaccagg ggccgttggc
     9781 gtgagccgct caccagtgcg agcaaaaccg gctgttgaag atccataatc agtcacgtac
     9841 ggggatgttc tcggcactgg ggggtagtga atggcgcaaa tctgttccct gaacggtcag
     9901 ttgtggtgct gaatggaaag cgacgcgggg atacgcaacg gcgcgcgccc ggcacggggg
     9961 aggggcgtgt gccgcccagg cggctgaaag gggtttgtcc gtgcctgcat attccggaag
    10021 cacttcacag acacagccac acactcaggt ggtatctgtc ccaccggctc tgaccgttcc
    10081 agtgatcgag gcagattttc ctcgccgtct gcacccgtat tggccaaagc ttcaggagaa
    10141 gtccaggtcc tggctgcgcg aaatgcgact catgccgccg gacaaggtcg agcggtacgc
    10201 ggacagcctc tgctacaccg acctggtggc gggctactac attggcgcgc cggatgagtt
    10261 gctcaccgcg atagccgatc tcagcagctg gttcttcgcc tgggacgacc ggcacgacag
    10321 ggactcggtg cacggcaggg cggcacagtg gcggtggctc tgccgcggcc tgcacggcgc
    10381 cctcgacgaa ccccggcagt acctccacca ccgcgacccc ctggtcgccg ggttcgcgga
    10441 ctgcgtccgc cgcctgtacg ccttcctcgg ccccagctgg aacgccagat tcgcccgcca
    10501 cttccacccc gtgatcgagg cgtacgacca ggagttcaga aaccggcgca gcggcacggt
    10561 ccccacggtc gaggcgtacg tggagctgcg ccgcctcacc ttcgcgcact gggcctggat
    10621 cgacctgctc gaacccaccg cgcgccacga actgccgcgc gccgtcagga aacagcccgc
    10681 gtaccgaaag gcggccctcg cgacccagga cttctcggcc tggtacaacg acctgtgctc
    10741 actccccaaa gaactcgcgg gagacgaact gcacaatctc gggatcagcc tcatcaagca
    10801 cgaggggatg acgctcgaac aggccgtacg ggacgtccac cggcgggtca cccaatgcgt
    10861 cgcggatttc ctcgaagccg aaaacgaagt gcggctgctc gtcgatcgac tgtccgacgg
    10921 aaccgcagaa ggaaagaaac tcgcggacac ggtggaatcc tgcgtcttca atatgcggaa
    10981 ctggttctct tccgtgtact ggttccatca cgaatccgga cgctatcggg tggacagctg
    11041 ggacgaccgg tccattcccc cgtatgtgac agaagatgcc ctggcggaaa acgaactggt
    11101 gggtgaggaa tgagcatcga atccgcgata cccgtaccgg ccgcgtcagg acccggcccg
    11161 ctgcgcaccc cgccgctcgt caagggcggc gcccccctgc tcggccacgc ctggaacctg
    11221 gtgcgcgacc cgctcggctt cctctccgcg ctgcgcgacc acggagatct cgtacggatc
    11281 aggctggggc ccaggacggc gtacgcggtc tgcgacccgg agctggtcgg cgccctcctg
    11341 aagcgccccg agttcatcgt cggcgggccg ctctgggaga ccctcgaagt gctcctcggc
    11401 aagggcgtgg cgaccagcaa cggcaagctg caccggcgcc agcggcggat gatgcagccc
    11461 gcgttccggc ccgagcggat cgccgattac gccaaggtga tggaggagga ggcgcgggcc
    11521 acggcggccc gctggagccc gggggcgacg gtcgacgtga gcgcggagat gttccgcacg
    11581 gccgtgcgca tcgtctcgcg ctcgctcctg gaggtggagt cgatcggcga gaaggccgac
    11641 cgcatcgccg actcgctgca caccgtcttc cagggcctct accgcaggat ggtgctctcg
    11701 gtcggaccgc tctaccgcgt gccgaccccc gccaaccggc gcttcgagag cgcgctcgcc
    11761 gacctgcacg cgctcgtcga cgagatcatc gcggagcgcc gcgcggcggg gcccggcgga
    11821 ccggacgacc tgctcgcgga attgctgcgg gccacggacg aatccggggc acccatagcc
    11881 gaccaggaga tccacgacca cgtggtttcc ctcgtcgtcg ccggagcgga gaatgtcgcg
    11941 tcgacgctgg catggacctt ccagctgctc accgaacacc cggagcagga aaggcggttg
    12001 gttgaagagg taaattccgt ggtcggggat cgcgcgatca cattcgccga tctgggcgcc
    12061 ctgccgcacc tccgcaatgt catcacggag gccatgcgca tacggcccgc cgcctggata
    12121 ttcacgcgtc ggtccgtggc cggaaccgaa ctgggcggct atcgcattcc ggccggtgcg
    12181 gacatcgtct acagcgtgta cgcgatgcag cgcgacccgc gttccttcga gcggcacctg
    12241 gagttcgacc cggaccgctg gaaaccggaa cgcgccgccg acgtaccgga gttcgcgatg
    12301 atgccgttca gcgtcggcaa ccgaaagtgc cccggggacc acttcagcct ggccgaactg
    12361 gccctgatcc tggggacagt ggtaccgaag tggcgcctgg cgccggtcgc ggagaccgac
    12421 gccggcaccc gcgtcgggat caccctgcac cccaagcgcc tcgtcctgcg ggccgaaccg
    12481 cgctgaggga gccgccgtgc cccgggtgtg tccgccccgc cccccgtgac ggggcggaca
    12541 cacacgctcc tagaactcgt cgtcgaagga gaccgacccc tcgacggcga cctggtaggc
    12601 cgagggccgc cgctcgaaga agttggtcag ctcctgcacg ccctgcaact ccatgaagga
    12661 gaacgggttc tccgagccgt agaccggcgc gaagcccagg cgttggaggc gctggtcggc
    12721 gacgcactcc aggtaggcgc gcatcgagtc ggtgttcatg cccggcagac cgtcgccgca
    12781 cagatcgcgg gcgaactgca gctcggcctc gacggcctcc ttcagcatgt ccgtgacctg
    12841 cgtctggagc gcgtcgtcga acagctcggg ctcctccttg cggaccgtgt ccaccacgtc
    12901 gaaggcgaag ctcatgtgca tcgtctcgtc gcggaacacc cagttcgtgc cggtcgcgag
    12961 gccgtgcagc aggccacggc tgcggaacca gtacacgtag gcgaacgccc cgtagaagaa
    13021 gaggccctcg atgcacgcgg cgaagcagat gaggttgagc aggaagcggc ggcggtcggc
    13081 ctgggtctcc aggcggtcca gcttctcgac cgagtccatc cacttgaagc agaactgcgc
    13141 cttctcgcgg atcgagggga tctcctccac cgcgtcgaac gcggccgccc ggtcctcggg
    13201 gtcgggcaga taggtgtcga gcagcgtcag atagaactgg acgtgcacgg cctcctcgaa
    13261 gagctggcgg ctcaagtaca gccgcgcctc gggggagttg atgtgcttgt agagcgtcag
    13321 caccaggttg ttggagacga tcgagtcgcc ggtcgcgaag aacgcgacga gccggccgat
    13381 caggtgctgc tcctcgggcg tcatcttcgc caggtcggtg acgtccgagt ggaggtcgac
    13441 ctcctccacc gtccaggtgt tcttgatcgc gtcccggtag cgctcgtaga agtccgggta
    13501 gcgcatgggg cgcagggtca gctcgaagcc cgggtcgagg aggttcttct cggagttggt
    13561 ggtgctggac attactggca ggcctcgcag gactcggggt tttccaggga gcaggcgacg
    13621 gcctcttcgg ccgtgacctg cgcggggacg ggggcgggtg cggtggcggc cgcgccggag
    13681 ccgccggccg cgcgggcgat gcgggtggcg gggcgcgagc gcaggtagta cgtggtcttc
    13741 aggccctgct gccaggcgta ggcgtacatc gaggagagct tgccgatggt cggcgtctcc
    13801 aggaagaggt tgagcgactg cgcctggtcg aggaagggcg tgcgcgcggc ggccatgtcg
    13861 atcaggccgc gctgcgggat ctcccacgcc gtgcggtaga gcgcgcggac ctcctcgggg
    13921 atccagctga agccctgcac cgagccgttg gcctcgcgca gcgcctcgcg ggtctgcgcg
    13981 tcccagacgc cgagccgctt cagctcctcc accagatagg cgttgacctg gaggaactca
    14041 ccgctgagcg tctcgcgctt gaagaggttg gagacctgcg gctcgatgca ctcgtagaca
    14101 cccgcgatgg acgcgatggt ggcggtcggc gcgatggcga gcagcagcga gttgcgcatg
    14161 ccggtcgcgg cgatacgttc ccgcagggcc gcccaccgct gcggccaggt cagctcgacg
    14221 ccgtagtggt cggggtggag cacgccgcgc gcggtgcggg tcttctccca ggcgggcagc
    14281 gggccgttgc gctcggcgag gtcggcggag gcctcgtacg cggcgagcat gatccgctcg
    14341 gcgatgcggg tggagagcgc gcgcgcctcg ggggagtcga agggcagctt cagttggaag
    14401 aagacgtcct ggaggcccat cgcgccgagg cccaccgggc gccacttggc gttggagcgc
    14461 ccggcctgct cggtcgggta gaagttgatg tcgacgacgc ggtcgaggaa ggtcacggcg
    14521 gtgcggaccg tctcgtccag ccgctcccag tcgatgtccc gggtcgccgt gtccacgaac
    14581 gcgccgaggt tcaccgagcc gaggttgcac acggccgtct cgccgtcgtc cgtcacctcc
    14641 aggatctccg tgcagaggtt ggaggagtgc acggtgtggc cgggctcggc ggtctggttg
    14701 gcggtgcggt tggcggcgtc cttgaacgtc atccagccgt tgccggtctg cgcgagggtg
    14761 cgcatcatgc ggccgtacag gtcgcgggcc gggatggtct tcttcgccag cccggcggcc
    14821 tccgcggcgc ggtaggcggc gtcgaactcc tcgccccaca ggtccaccag ctcgggcacg
    14881 tcggccgggg agaacagcga ccagtcctgg tcggcggcga cccggcgcat gaactcgtcc
    14941 gggatccagt gcgcgaggtt gaggttgtgc gtgcggcgcg cgtcctcacc ggtgttgtcg
    15001 cgcagctcca ggaactcctc gatgtcggag tgccaggtct ccaggtagac ggcggccgcg
    15061 cccttgcgcc ggccgccctg gttcacggcg gcgaccgagg cgtccagtgt cttcaggaac
    15121 ggcacgatgc cgttggagtg cccgttcgtg ccccggatca gcgaaccccg ggaacggatg
    15181 cgggagtagg agaggccgat gccgcccgcg tgcttggaga gccgcgcgac ctggtggtag
    15241 cggtcgtaga tcgagtccag ctcgtccagc ggggagtcca ggaggtaaca ggaggacatc
    15301 tgggggtgcc gggtgccgga gttgaagagc gtcggcgagg acggcaggta gtccaggcgg
    15361 ctcatcaggc ggtacagcga ggcgacctcg tcgagcgcgc gctcgctgcc gtcctccgcg
    15421 aggccgctcg ccacgcgcag catgaagtgc tgcggggtct cgatgacctg acgggtgatc
    15481 gggtggcgca gcagatagcg gctgtgcagg gtgcgcagtc cgaagtactc gaagcggaag
    15541 tcggcgccgt cggcgagcgc ggcctccacc agcgcgtcca gccgggccgc gtgctcagtc
    15601 acgaaggacg ccgtgcggtc ggcgatcagg ccctcgcggt ggccgaccgc gacggagtcg
    15661 gtgaaggagt gcacgccctg cgtcgccgcc tcctcgcgga tgccgatcga caggagcctg
    15721 gccgccagct tggagtacgc cgggtcctcg gagatgagcc ccgccgccgc ctcggtggcc
    15781 agctcccgca gctccgactc gtcggcgcgc gccgagcggc cgcgcagcgc ggcggcggcg
    15841 acccggccgg ggtcggcgtc ggggaggtcg gcggtgaggt cggtcagggt gcgcagcagc
    15901 gcggcccctg gcccgtcggt tccttcggca ccctgggcgg tgggcgtcga cggcgctgac
    15961 gcgggttcgg cgggcgcgat ggtcacgtgg ggcactccct cgctcggctc tgggccaggg
    16021 ggagggaagg ggcgcacacg ggcgcacccg ggcagggcgg cgtaccgcgt ccaccggccc
    16081 actccacgag gcccggacgg tcggcacccg ggccggacgg ctcgggcgca ctgtcggcag
    16141 gtcttcggac tccgcgtacg ccaaaggcgt acacatgcac cgttgcggga cagttccgga
    16201 cttgcaccgg attcccctgc ggcgacagcg agcacgagca tacatcttgt gccgggcctc
    16261 tgaagcgggc ccacatcttg tgtcggctcg cggagtggtg gctagagctt cagcgcgtac
    16321 gtcagcagcg gcaccgtctc gatcgggcgc cagtcgcgct caggcgtccg tacgaagccg
    16381 aggcgttcgt agagccggtg ggcggcgtgc atggacgtct gcgtggacag cacgagcgag
    16441 gtgcggcccg cttccttggc gcgtcgcacg cactcccgta cgagcgcttc gccggcgccc
    16501 cggccgcgtg cctcggggga ggtggcgagc atccgtatct ccgcgtcgtt cgcgcccgcg
    16561 atgtcggcca tcggtccgcc ggacgggacg taggtgacgc tgccgagcac cttgcccgcc
    16621 gcctcggcga cgaggatctc ggcgtgcgcc gcgcgtcccg gcacgtcccg cagcacggcg
    16681 aggtaggggt cgtcctcccc gaagtccagg tgtccgtcgg cgagataggc ctgcgcggtg
    16741 agggcgccga gcgcctcgta ctcctcgggg tgtgcttctc tgatcgtgat gtccatgcgg
    16801 cgcagtgtgc aacacgggca tggcggaggg ccgccgattt tccacgacgg agggccgccg
    16861 aagttcacga cggagggccg ccggttttcc ggcggccctc cgcgtgacgg tgagtgggtc
    16921 agtgcccggc gcccgcggtc gccttgggca gctcctccat gacgccgggg tcgcccgcgt
    16981 ccgcggtgta gtccccgggg gaggtctcgt cgatgccctc cggggccttc agcgccttca
    17041 ggacgaaggt gaggaccacg gtgacgatca cgttcaggac gaacgcggtg aggccgatgt
    17101 agccgatctc gccgatgccc gggatcgtgt cggacgagcc gccgaagtgc ttctgcgtcg
    17161 gcgaggcgac gccgtacgcg gccagcgtgc cgtagaccat gccgaccgcc cagcccgcga
    17221 gcagcgccca gcggtggaac cagcgcgtga acaggccgcc gaccagcgcg ggcatcgtct
    17281 gcaggatcca gatgccgccc aggagctgga agttgatcgc gacggtcttg tccatggtga
    17341 ggacgaaggc gagcgcgccg accttcacca gcagcgagac cagcttggag accttggtct
    17401 cctgggcggg tgtcgcgtcg ggcttgatga agtccttgta gatgttgcgg gtgaagaggt
    17461 tcgcggccgc gatcgacatg atggccgccg ggaccagcgc gccgatgccg atggccgcga
    17521 acgccacgcc cgtgaaccag tcggggaaca tgtcctcgaa cagctgcggg atcgccaact
    17581 ggccgttctc caccttgatc ccggccgcga tcgccatgaa gccgagcagc gcgagcaggc
    17641 ccagcatcag cgagtacagc ggcaggatcg tggtgttgcg gcggatcacg tcacggctct
    17701 tggaggagag cgtcgccgtg atcgagtgcg ggtacatgaa gagcgcgagg gcagagccga
    17761 gcgcgagcgt ggcgtacgtc cactgcccgg cctcggcggg cgcgagcgcg ccgcgcggct
    17821 tgtcggtcgc cgggttggtc tgcgcgaagg cgtcacccgc cttggcgaag atgtcgtcga
    17881 agccgccgag cttgatcggg atgtagatga tcgcgacgac gatgacgagg tagatcagcc
    17941 cgtccttcac gaacgcgatc agcgcgggtg cgcgcagccc cgacgagtag gtgtacgcgg
    18001 cgagcaccgc gaaggcgatc aggagcggca gatccttgat gaaccagttg gtgtccgggc
    18061 cgccgcccac gcccatgacg tcgaggaccg cctggatgcc gacgagttgg agggcgatgt
    18121 agggcatcgt cgcgaggatg ccggtgaccg cgacggccag cgagagcccc ttggagccga
    18181 agcgcccgcg cacgaagtcg gaggtcgtca catagccgtg cttgtgcgag accgaccaca
    18241 ggcgcggcag gaaggtgaag atcagcggat agacgaggat cgtgtacggc accgcgaaga
    18301 acccggccgc gcccgccgcg tagatcgccg cggggacggc cacgaacgta tacgcggtgt
    18361 agaggtcgcc gccgagcagg aaccatgtga cccaggtgcc gaacgaccgg ccgccgaggc
    18421 cccattcgtc caggctctcg gtctcggcct tgcgccagcg ggcggcgagg aagcccatga
    18481 cggtgaccgc tatgaagaag aagatgaaga cggcgagcgc gacgccgttg actccgccgt
    18541 tcatgaccgc gcaccttcct tgcgggcgcg ctggtcacgc tgccacagct tgtacgcgat
    18601 catcgtgagc agggtcgaga tgagcaccca gagcatctgg taccagtaga agaacgggat
    18661 gccgatgaag gtcggttcga tcttcgcgta cgaacccacc cagagcatcg ccacgaaggg
    18721 tgcgacaagg caggccgcga tgaccacgcg gaccggcgtg accaccggtc tgttcacttc
    18781 aggcgcatct gacatgtcgc ggctccgttc cctcactgat cccgtgcttg acgtgcggga
    18841 aatctaagcc acggtctcgg tgtacggaac ccctgtccgt ataacggacg tatgtcggag
    18901 gggtcgaact ccctgctcag cagcagcgga acccctggcg gggatccgac tcctggcggt
    18961 ccgtccgcat acgctcgaac gcgcggcggc tgagaacggt cgccgccgga tggtccttgc
    19021 gcacgtgcgc cacgtaccgc tcgtacgccg actcgtcggt cagttcgcgg acgtaccacc
    19081 gcatccagcg cacgccccgc agcagccagg tcatcgcgtc ggctccgcct tctccaggct
    19141 gtccgccttc tccagggcct cccgtttctc ctccggcgtc gggaagaggc cggccggtgc
    19201 cgtcaaccgc gactccacga agggcgcttc gctcagccgg gacgcctcgg ggtcgctgat
    19261 gtgccggtag cagacccggg ccgcgtcgac gatcacgatg acgatgagca gggcgagcac
    19321 ggccgaaagg acgccgtcga ccgtggagtt ggtgacgatg gtgtgcatgt cgtccatgga
    19381 cttggcgggc ggcaggacct tgccgtcgtc gatggcgtcc tggtagatcg agcgctgggt
    19441 gaagaagccg acccgccggt cgccggagaa gaccttctgc cagctcgcgg tgagcgtcac
    19501 cgtcgcgtcc caggcgagcg ggaccgccgt gatccaggcc cacttgaggc ggccggactt
    19561 cacgagcagc gtggtgcaga cggtgagggc gacggcggcg aggagctggt tggcgatgcc
    19621 gaagatcggg aagagctggt tgatcccgcc gagcggctcg tgcacgccca cccacaggaa
    19681 gtagccccag aggccggtga cggccgcgct ggtcaggatg agccccggct tccagctcac
    19741 gttcctgaag ggcttgtaga cgttgccgag catgtcctgg agcatgaagc ggcccacgcg
    19801 cgtgcccgcg tcgagcgcgg tgaggatgaa gagcgcctcg aacatgatcg cgaagtggta
    19861 ccagaaggcc cgcatcgagc cgccggtgac cttcgagaag atctcggaga caccgaccgc
    19921 gagcgtgggc gcgccgcccg tgcgcgagag cagcgaggac tcctccacgt tcttcgcggc
    19981 ctgcgccagc tcggcggggg agatggagta gccgaagccc gcgaccgcct tcgacgcctc
    20041 ctgcacggtg tcgccgacga cacccgccgg tgcgttcatc gcgaagtaca gacccgggtc
    20101 gatgatcgac gccgcgacga gcgccatgat cgccacggcc gactccatca gcatggagcc
    20161 gtatccgatc atccggacct gcgtctcctt ctggatcatc ttcggcgtcg tgcccgagga
    20221 gatcagcgcg tggaagccgg agagcgcccc gcacgcgatg gtgatgaaga cgaaggggaa
    20281 gagcgagccc gcgaagaccg gcccgtcgcc gcgcgaggcg aagtcggtca ccgggtccat
    20341 cttcagcgtc ggcagggtga cgaggacgcc gagcgcgagc agcaggatgg tgccgatctt
    20401 catgaaggtg gagaggtagt cgcgcggcgc gagcagcatc cacaccggca ggatcgaggc
    20461 gacgaagccg tacgcgacca gccagaccac cagcgtcgag ggcgcgagcg tgaaggtgtc
    20521 cgcgagcgag gactcggcga cccagcgccc ggcgaccagt gcgatcagca gcagcgcgat
    20581 accgatgagg gagacctcgc tgacccggcc cggacgcagg acgcgcaggt agaagcccat
    20641 cagcagcgcg atcgggatgg tcatcgcgat ggagaaggtg ccccacggcg actcggcgag
    20701 cgcgttgacg atcaccaggg cgagcacccc gagcaggatg atcatgatgg cgaatgcggc
    20761 gagcagcgcg gcggccccgc cgaacggccc gatctcgtcc cgcgccatct gcccgagcga
    20821 cttgccgtcg cgccgcgtcg agaagaacag gacgaccatg tcctgcacgg cacccgcgaa
    20881 gatcacgccg acgacgatcc agatcgtccc cggcaaatac cccatctggg cggcgagcac
    20941 gggccccacc agcggccccg cgcccgcgat cgccgcgaag tggtggccga gcaggacgcg
    21001 gcggtcggtc gggtggtagt cgatgccgtt gtcgagccgt tcggcgggcg tggcccggcg
    21061 cgcgtcgacc ctcaggaccc ggtaggcgat gaacttggag tagaagcggt acg
//
