LOCUS       NZ_CP029617            22562 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 01529 chromosome, complete genome.
ACCESSION   NZ_CP029617
VERSION     NZ_CP029617.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 01529
  ORGANISM  Streptomyces sp. WAC 01529
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8270461)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. May-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945545.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 04:27:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,297
            CDSs (total)                      :: 7,207
            Genes (coding)                    :: 7,110
            CDSs (with protein)               :: 7,110
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 33 of 97
            Pseudo Genes (incomplete)         :: 81 of 97
            Pseudo Genes (internal stop)      :: 9 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 379574
            Orig. end                         :: 402136
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029617.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22562
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22562
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22562
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12562](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12562
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(34..49)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.92"
                     /tool="antismash"
     misc_feature    231..246
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     gene            complement(313..3363)
                     /locus_tag="DMA15_RS01710"
                     /old_locus_tag="DMA15_01710"
     CDS             complement(313..3363)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1218: Exonuclease"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379746.1"
                     /locus_tag="DMA15_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01710"
                     /product="SMC family ATPase"
                     /protein_id="WP_125510886.1"
                     /transl_table=11
                     /translation="MRLHRLRVTAFGPFGTTQDIDFDELSAAGLFLLHGPTGAGKTSVL
                     DAVCYALYGSVPGARQGSGQGMTLRSDHAQQGTRTEVCLELTVAGRRLEITRQPPWARP
                     KKRGTGTTTEKAQSWLRESTPEGGWKDLSRSHQEIGEEIAQLLGMSKEQFCQVVLLPQG
                     DFARFLRADAEARGKLLGRLFDTRRFAAVEQRLVEQRRTTAAEVKDGDAALLADAHRMQ
                     QAAAEDGREAELPLPDLAPGDPGLATEVLAWAAVARTTARERLTIADGALTAAESAQVA
                     AERRLGDVRELDRLQSRFAEAQERAARLHAREAERRECEQRLERARKAETVAPALALRD
                     AAEAEHRRAAQEETRARGRLPGTFEAAGASGLAAAARKAAEELGGLGSARRAEQRLADI
                     AAERAALDRQERADDEVSQDAAGWLDGWEATRAALQERVESAQEAATHAERLAGRLEPV
                     RTRLDAARRRDRLAQDAAAAQDRALTAREHATSTHEHWLALKEQRLTGIAAELAAHLTD
                     GEPCAVCGATEHPAPARKSAGHVDRGAEEEALSAHRAALESRTAAERELSDVQASLAAA
                     TAAARSGETGADESAPGGTEPSVEELAAAVEELRRAHAEARDHASGLHAAREALARAER
                     EYDRRVTGRQEAARRAASRATLREALDREQNALEEELTHARGTTGSVAARAAQLERQAA
                     LLTEAADAVRVADETAERLKAADARLADAAFRAGFDTPVAAADALLDDARHRELQHRLD
                     AWRNEEAAVRSVLAEPDTATAAQQPPADLPAAREEAEAAARRLRAAASARDAAARRCAE
                     LDRLSARTAAGTRGLAPLRAAHDRVARMAGLAAGTSADNERRMRLESYVLAARLEQVAA
                     AATVRLRRMSSGRYTLVHSDDRTGRGRSGLGLHVVDAWTGRERDTATLSGGETFFASLA
                     LALGLADVVTDEAGGVRLDTLFIDEGFGSLDDQTLDEVLDVLDSLRERDRSVGIVSHVA
                     DLRRRVHAQLEVVKGRAGSVVRQRGAA"
     gene            complement(3360..4523)
                     /locus_tag="DMA15_RS01715"
                     /old_locus_tag="DMA15_01715"
     CDS             complement(3360..4523)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1230: Nuclease SbcCD,
                     D subunit"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122335.1"
                     /locus_tag="DMA15_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01715"
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="WP_125510887.1"
                     /transl_table=11
                     /translation="MRLLHTSDWHLGRSFHRVNMLDAQAAFIGHLVTTAREREVDAVLV
                     AGDVYDRAVPPLAAVELFDDALHRLADLGVPTVMISGNHDSARRLGVGAGLIDRAGIHL
                     RTDPAACAEPVLLADDHGDVAFYGLPYLEPALVKDEFGVAKAGHEAVIGAAMDRVRADL
                     ATRARGTRSVVLAHAFVSGGQISDSERDITVGGVAAVPAGVFEGVDYAALGHLHGSQTL
                     GTRVRYSGSPLPYSFSEADHRKSMWLVDLGPEGQIEAERVDCPVPRALARIRGTLDELL
                     DDPGLTRHEEAWVEATLTDAVRPDDPMARLCARFPHTLSLVFDPDRAPDDPDVSYAQRL
                     QGRSDEQIAEDFVAHVRGAGPDGHERAVLRSAFDAVRADDTLREVAR"
     gene            complement(4619..5245)
                     /locus_tag="DMA15_RS01720"
                     /old_locus_tag="DMA15_01720"
     CDS             complement(4619..5245)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027706.1"
                     /locus_tag="DMA15_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01720"
                     /product="YigZ family protein"
                     /protein_id="WP_125510888.1"
                     /transl_table=11
                     /translation="MQDEYRTVAREGVHETEINRSRFLCALAPAATEREAQDFVARVRK
                     EHPTASHNCFAYVIGADAAIQKASDDGEPGGTAGVPMLQMLLRRDMRYVAAVVTRYYGG
                     VKLGAGGLIRAYGGAVGEALDTLGTVTRRRFRLATVTVDHQRAGKVQNDLRAAGREVRD
                     VRYGDAVTIEIGLPDADVDAFRGWLADATAGSAVFELGGEAYGDA"
     gene            5406..6098
                     /locus_tag="DMA15_RS01725"
                     /old_locus_tag="DMA15_01725"
     CDS             5406..6098
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (101-166). E-value: 3.3e-16. Score:
                     51.3. Matches aSDomain:
                     nrpspksdomains_DMA15_RS01725_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638779.1"
                     /locus_tag="DMA15_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01725"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_125517186.1"
                     /transl_table=11
                     /translation="MASLLAAVPVTVVETYGDPADAVLFPEEEAVVAKAVAKRRDEFTT
                     VRHCARAALHLIGVPPAPILPGQRGAPRWPDGVVGSMTHCAGYRAAVVARAGEVTSLGV
                     DAEPGEPLRDPDVLTMIADESERAALAALGARHPGTPWDRLLFSAKESVYKTWFPLTGR
                     WLGFEDARVRLDPDGTFTARLLVEGPVVEGVELKVFSGQWIVRDGIAATAIVLPITTPA
                     DPSSAVHA"
     aSDomain        5709..5903
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMA15_RS01725_ACPS.1"
                     /evalue="3.30E-16"
                     /label="DMA15_RS01725_ACPS.1"
                     /locus_tag="DMA15_RS01725"
                     /protein_end="166"
                     /protein_start="101"
                     /score="51.3"
                     /tool="antismash"
                     /translation="LGVDAEPGEPLRDPDVLTMIADESERAALAALGARHPGTPWDRLL
                     FSAKESVYKTWFPLTGRWLG"
     gene            complement(6141..7775)
                     /locus_tag="DMA15_RS01730"
                     /old_locus_tag="DMA15_01730"
     CDS             complement(6141..7775)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009299120.1"
                     /locus_tag="DMA15_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01730"
                     /product="amidohydrolase"
                     /protein_id="WP_125510889.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.7e-10, bitscore:
                     37.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLVFLGTTRTGSHPHHDTTALAVRDGRVLALGDEARALAATAD
                     EVVDIGDGLLMAAFGDGHAHPLFGGLESFGPQIKELASVDAIVSEVGRWAGEHPEAEWI
                     VGASYDPALAPDGEFDARWLDAAVPDRPVVLRAHDYHTVWCNTEALRRAGVSESTPEPR
                     LGWIVRRPDGTPLGTLREWHACDLVLDQVPSRATDELVEAVRRAGHAYARAGITWVQDA
                     WVEPEMADAYLTAARRDALAFRVDLAQRADPDRWRGQLAPFAETRARVAAEGGELLTAR
                     TVKFFSDGVIEGGTAAMLAPYLDASHSCGMPVWEPRALAEAVRAFDAAGFQTHIHAIGD
                     AGVRASLDAIETAIHANPAWDRRPVITHVQLVDPADLPRFAALGVIANFEPLWAQPDPL
                     QTELSIPRLGAHRAALQYPMGELARDGVRLSFGSDWPVSSHIPLEGIQVAVTRRTFTGE
                     PAEGWIPHQRLTVEEALTAATAGVAHQAGADDRLRLAPGAPADLVLLSADPRTADPMAI
                     RHARVRGTWLGGRPTYRAAASSRAAAP"
     gene            complement(7866..9344)
                     /locus_tag="DMA15_RS01735"
                     /old_locus_tag="DMA15_01735"
     CDS             complement(7866..9344)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006344840.1"
                     /locus_tag="DMA15_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01735"
                     /product="APC family permease"
                     /protein_id="WP_240659648.1"
                     /transl_table=11
                     /translation="MTAPPSSVPPPSVPTSPPSSHGLSGGAVGTGDLVFFVMAAAAPLT
                     VMAGVAPLAIGMAGRAAPLGYLLSGLLLIVFAAGFTAMSRYVRNAGAFYAYIGRGLGRP
                     AGAGSAYVALFSYNAIEVGLLAAFGWFTESGFEDLTGAHVPWWVWASGGLVAIGALGYL
                     RVTLSAKVLGVALVLEVLVLLAFEAGVLAHGGGPRGVDLGALSPGHLGASGAGGMFVLA
                     IGAFVGFEATAIYAEEARRPERTVPRATYIAVAFLALFYTFTVWMIINAYGDRAQAVAN
                     GEGGADMVFTATERFSGAWAADSMHVLIITSAFAATLAFHNGAARYFYALGREGLLPAR
                     LGTVSAKTRAPAAAVLTQSALALAVIVVTVVSGVDPYTVTFLWTNGSGILGVMLMQALA
                     ALAVYGFFRRDRRALPAWRVVAAPLLACAGLAVMIVLVCAHLDLLTGASTGVNAALILP
                     LPVLFVVGAMLALRVKARDPMAYERLTTVDAESV"
     misc_feature    complement(9592..9603)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.84"
                     /tool="antismash"
     misc_feature    complement(9593..9606)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.36"
                     /tool="antismash"
     gene            9864..9974
                     /locus_tag="DMA15_RS01740"
                     /old_locus_tag="DMA15_01740"
     CDS             9864..9974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016638602.1"
                     /locus_tag="DMA15_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01740"
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_125510890.1"
                     /transl_table=11
                     /translation="MKKAYEAPSLVRLGTFRKKTGLLARSGNDRLIFSKN"
     gene            10001..11839
                     /locus_tag="DMA15_RS01745"
                     /old_locus_tag="DMA15_01745"
     CDS             10001..11839
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057605464.1"
                     /locus_tag="DMA15_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01745"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_125510891.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.9e-46, bitscore:
                     157.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELHESAGTGPGDAHFTVFNDRADAAAVARSFAHPGTRVLNHSS
                     GRPWLVGQWADEEIVTARVGRAALAVIGCCPVTTAELEARAGRLRDLTELDVWARSLPG
                     SFHLVAALDQRLRMQGTASGLRLVFHATVDGVPLAATRADVLAAALGHDPDEEQLAIRL
                     LWPAPYPLFETSLWYGVTAVPPQDALIVGADGRTVHHSRWWTPPEPVRTLADGAPLVRE
                     ALATAIDARTRQGGVVSCDLSGGLDSTSICFLADRSPAKVVASTWPGRDPADTDLHWAE
                     RAVKHLPDVEHVVWDAHASPLVYDDLLNIDDLLDEPTIGVMDRSRVLSHLPDMARRGSR
                     VHMTGIGGDHVAWCSEAYYHRLSRTRPLFALRQLRGFRALWQWPLGTTARALADSRPYG
                     RCLADAVGHLRDPLPASATTSLGWGMPPRLFEWVTPDATRMVERALREAASTVVPLHPD
                     RGMHADLEQIRSCTRIIRQWDRMAARVGVPMASPFLDDRVIEACLAIRPEERVTPWAYK
                     PVLTTAMRGIVPEECLRRTTKAAAAMDAADGLRKHRADLLALWEDSRLERLGLVDGETL
                     RRLAQRPSAPGLRDGILYSTIAAEVWLRGLSPARTR"
     aSDomain        11871..12023
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DMA15_RS01750_Lasso_Fused_RRE.1"
                     /evalue="9.20E-09"
                     /identifier="RREFam003.1"
                     /label="DMA15_RS01750"
                     /locus_tag="DMA15_RS01750"
                     /protein_end="51"
                     /protein_start="0"
                     /score="26.3"
                     /tool="antismash"
                     /translation="MALQFGPDVSTTETDYGTVLLDQRSGNYWELNPTGSLVVKTLLDG
                     GEEAAA"
     gene            11871..12125
                     /locus_tag="DMA15_RS01750"
                     /old_locus_tag="DMA15_01750"
     CDS             11871..12125
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988506.1"
                     /locus_tag="DMA15_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01750"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_125510892.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.4e-06,
                     bitscore: 26.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.2e-25,
                     bitscore: 88.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-16, bitscore: 58.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALQFGPDVSTTETDYGTVLLDQRSGNYWELNPTGSLVVKTLLDG
                     GEEAAAIDALICEFDIDRARAQQDVTTLVRELRDAGLVS"
     aSDomain        11874..12119
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DMA15_RS01750_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.60E-28"
                     /identifier="RREFam002.1"
                     /label="DMA15_RS01750"
                     /locus_tag="DMA15_RS01750"
                     /protein_end="83"
                     /protein_start="1"
                     /score="88.1"
                     /tool="antismash"
                     /translation="ALQFGPDVSTTETDYGTVLLDQRSGNYWELNPTGSLVVKTLLDGG
                     EEAAAIDALICEFDIDRARAQQDVTTLVRELRDAGLV"
     gene            12122..12562
                     /locus_tag="DMA15_RS01755"
                     /old_locus_tag="DMA15_01755"
     CDS             12122..12562
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987089.1"
                     /locus_tag="DMA15_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01755"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_125510893.1"
                     /sec_met_domain="PF13471 (E-value: 3.2e-21, bitscore: 74.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALERPTGVPFTRRLAARLVLLPAVALSLLPPRRIRTVLGV
                     VRRGAAPATAAQAKKARDAMCATSLLCAGPKGCLPRSLGSALLCRLMGGWPTWCTGASV
                     VPPFNAHAWIEAEGRPIGEEMPDDYFARLLSVGPAGTSRAGC"
     gene            12631..13086
                     /locus_tag="DMA15_RS01760"
                     /old_locus_tag="DMA15_01760"
     CDS             12631..13086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675687.1"
                     /locus_tag="DMA15_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01760"
                     /product="TerB family tellurite resistance protein"
                     /protein_id="WP_125517189.1"
                     /transl_table=11
                     /translation="MALWDRVKESASTMQTQLLAKKNDLKSGAFRDASMAMCALVAAAD
                     GTVDPTERARVAQLIGANEVLQNFPADDLRRRFDAYVDKLTADFAFGKVSVLQEVAKAR
                     KKPAEARAVIQIGIVIGGADGDFDKDEQAVVREACFALDLPPHEFDL"
     gene            complement(13140..14072)
                     /locus_tag="DMA15_RS01765"
                     /old_locus_tag="DMA15_01765"
     CDS             complement(13140..14072)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313596.1"
                     /locus_tag="DMA15_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01765"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_125510894.1"
                     /transl_table=11
                     /translation="MGVFVFLPLVLPLTAWPVARLAEHHLHPRTATRVLTSVAGVMALC
                     STLCLALLMVVGTAQLPGNPLPDAWSDPEVRAAVPYYEVAGKAAIPALLAVCAACARTL
                     WRHARVRLRGRRALEGLPGTSVAVLPDDAPYAYALPARDGGRVVVTTGMLNRLAAPERR
                     ALFAHERAHLTARHHRHLLVTQLAARANPFLRPLRTSVAFTAERWADEAAARAVRDRRV
                     VARAIGRAALVSRGAPAPALAGFATPGPVPRRVAALLAPAPAARTRPSLFTAVGLALWC
                     AAFGTVVSAMSSANSAVTMVLILRAATPL"
     gene            complement(14096..14503)
                     /locus_tag="DMA15_RS01770"
                     /old_locus_tag="DMA15_01770"
     CDS             complement(14096..14503)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474973.1"
                     /locus_tag="DMA15_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01770"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_125510895.1"
                     /transl_table=11
                     /translation="MEHHDKREERRPRLRRRAQGELEQQVLAALHAARGPVSAAWVQER
                     IGGDLAYTTVMTILTRLLAKDVVTRERAGRSFAWTSASDEAGLAAFRMRKVLDGESDRE
                     AVLASFVTTLTPDDEQLLRELLGRAGAETDD"
     gene            14653..15228
                     /locus_tag="DMA15_RS01775"
                     /old_locus_tag="DMA15_01775"
     CDS             14653..15228
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976436.1"
                     /locus_tag="DMA15_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01775"
                     /product="TerD family protein"
                     /protein_id="WP_125510896.1"
                     /transl_table=11
                     /translation="MGVSLAKGGNVSLSKEAPGLTAVLVGLGWDVRTTTGTDYDLDASA
                     LLCDDSGKVVSDQHFVFYNNLTSPDGSVEHTGDNLTGEGEGDDEAVKVNLAQVPDQITK
                     IVFPVSIHDAENRGQSFGQVRNAFIRVVNQADGVEIARYDLSEDASTETAMVFGELYRH
                     GAEWKFRAVGQGYASGLRGIATDFGVNV"
     gene            15276..15683
                     /locus_tag="DMA15_RS01780"
                     /old_locus_tag="DMA15_01780"
     CDS             15276..15683
                     /GO_function="GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014141167.1"
                     /locus_tag="DMA15_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01780"
                     /product="CoA-binding protein"
                     /protein_id="WP_125510897.1"
                     /transl_table=11
                     /translation="MYGDQKTVRKILTELGDTWAVVGLSDNRERAAYGVAAVLRGFGKR
                     VVPIHPKAGTVHGEQGYPSLSAVPFEIDVVDVFVNSGLAGQVADEAVAAGARAVWFQLG
                     VIDEAAYERTRAAGLDMVMDRCPAIEIPRLG"
     gene            complement(15739..16800)
                     /locus_tag="DMA15_RS01785"
                     /old_locus_tag="DMA15_01785"
     CDS             complement(15739..16800)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019074954.1"
                     /locus_tag="DMA15_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01785"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_125510898.1"
                     /transl_table=11
                     /translation="MAGQDIPQEYLDGYAHILAAASSTGRRLTRDELASRRVLGERAAD
                     AGFGLRALVGAHLAATRAHWPAERALSVDCALAAAEQAMDAFAEGYERAQRLAVRQEEA
                     ARREFIDDLLYGRSDLGLLAERAERFGLRLSYEHAVAVAEGPDGYEEGHAVPREVERAL
                     IGRFGDRSILLTTKDGRLVCVAPGDQDEVLTFFAKHAYAVTDGGRVAIGRPQPGPGGVV
                     QSYEEALNALDLAGRLELDDPVLHAADLLVYPVLTRDRQAMADLVLNTLGPLRQARGGA
                     QPLIDTLAAYFDSGCVAAEAARRLTLSVRALTYRLERIHGLTGANPSDPVHRYTLQTAV
                     IGARLLDWPSKQF"
     misc_feature    16834..16849
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            16942..17382
                     /locus_tag="DMA15_RS01790"
                     /old_locus_tag="DMA15_01790"
     CDS             16942..17382
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010275104.1"
                     /locus_tag="DMA15_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01790"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_125510899.1"
                     /transl_table=11
                     /translation="MPLTGEYEPGTWDWATKQTELYESSGGTEGTTLRGKPVIVLTSIG
                     AKSGKLRKNPLMRVEHDGEYAVVASKGGDPANPSWYHNLIAHPHVELQDGPVKKDYRAR
                     VVTGEERRIWWERAVAVWPDYDDYQKKTAREIPLFVLTPVES"
     gene            complement(17513..18118)
                     /locus_tag="DMA15_RS01795"
                     /old_locus_tag="DMA15_01795"
     CDS             complement(17513..18118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019525685.1"
                     /locus_tag="DMA15_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01795"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_125510900.1"
                     /transl_table=11
                     /translation="MTWPATARYRLEAAPGGLGLVQDLLNTVAAGAPPHPDLLDGRASA
                     QEWAKEVVAEWTSATGQPAPRVTLDAEGLRELRSFRETLGKLVAGQGQEQGEAAGGLGP
                     GGAYSGEAALRLGEDGVVRLEPRGTGGAHLVALALAAVYEGQQTDTARRLKTCRNPLCR
                     VAFYDRSRNNSGVWHDVRTCGNAANLRAYRARRRQQES"
     gene            complement(18184..19377)
                     /locus_tag="DMA15_RS01800"
                     /old_locus_tag="DMA15_01800"
     CDS             complement(18184..19377)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189264.1"
                     /locus_tag="DMA15_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01800"
                     /product="12-oxophytodienoate reductase"
                     /protein_id="WP_125510901.1"
                     /transl_table=11
                     /translation="MEKTDATPSPPNAPSVPSAPSVLTDTALDSRSRAARLLGQPFALG
                     DLTLRNRIAMAAVTRRFSPGGVPGEDVAAYYARRAAGGAGLIVTEGTYVGRDAAAAYDR
                     VPHFHGEKALAGWARVVERVHGAGGRIMPQLWHTGVLRTDAVPPLGVPAEGPSGIDLDG
                     RPHGRAMTLDDIDAVVEAFAEAAAAAERIGFDGVELHGAHGYLIDAFLWHGTNTRGDAY
                     GGDHASRARFAAEIVAAVRAVVSPGFPVVFRLSQWKTDHYEARVAENPAELEQLLTPLA
                     AAGVDAFHASTRRYWLPEFAGSDLNLAGWAKKLTGRPSITVGSVGLDRQFAGAPGRAQR
                     SGVTGIDPLLDRLERDEFDLVAVARALVADPGWPVKALTGRLDKAVPYDASLLDALV"
     misc_feature    complement(19420..19440)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            19556..20425
                     /locus_tag="DMA15_RS01805"
                     /old_locus_tag="DMA15_01805"
     CDS             19556..20425
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982886.1"
                     /locus_tag="DMA15_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01805"
                     /product="MoxR family ATPase"
                     /protein_id="WP_125510902.1"
                     /transl_table=11
                     /translation="MTTGYFTSVDEVAVRLAEAGYLASPAVATTVFLADRLGKPLLVEG
                     PAGVGKTELAKAVAQVAGARLIRLQCYEGVDESRALYEWNHAKQLLRITAGRDESWDET
                     RTDIFSEEFLLSRPLLTAIRGTEPKVLLIDETDKADVEVEGLLLEVLSDFQVTVPELGT
                     ISAERRPFVVLTSNASRELSEALRRRCLFLHIGFPEEELERRIVRMRVPGLDEVLADAV
                     VRVVGALRAMDLRKVPSVAETIDWARTLLALGVGTLDETVVRDSLGVVLKHQDDVLKAA
                     AKLDLDAV"
     gene            20503..21888
                     /locus_tag="DMA15_RS01810"
                     /old_locus_tag="DMA15_01810"
     CDS             20503..21888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057680.1"
                     /locus_tag="DMA15_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMA15_01810"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_125517191.1"
                     /transl_table=11
                     /translation="METRAEGVTGRLTGLVRALRSHGLRIGPGETVDAAAALEALGLAD
                     RERVREGLAAALLHQESQRAVFDPVFELYFPLGRGVSAQEGGAEPDREALRERLVAALA
                     ADDQALLGRLAREAVDGFGGYGSAQGSDGWSSHQTLSRLRPETLLARVLAALRAGATGA
                     PEGAAAFTDRLEPDEIRRRIEGFRERVRTEARRRVAERRGTEEIARRAVATSADRVDFL
                     LAGRAQLDELRRAVYPLARKLATRLAARRRRAAHGSIDLRRTLRGSLSTGGVPMRPVLR
                     RRRPARPELVLLCDVSGSVAGFANFTMLLVQALHDQFSKVRVFAFVNRADEVTGLLARG
                     SADPAGLGARILGEAAVTGWHGSSDYGTSLCEFAERHLDAVGPRTTVFVLGDARTNMSD
                     PNLPALRQIAGRARRVYWLNPEQRAQWSTGDSAAYAYAELVEMHECRNARQLGELIARL
                     LPV"
     misc_feature    22425..22440
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.44"
                     /tool="antismash"
ORIGIN
        1 cgccgcggcc ggcgacggag tgcatcttgg agatgctcgc ccccagcttg accttgtcgt
       61 actcggcgcg cgtgatggtc ggcgaagccg cctgcgcggt gggggccagg gtggcggtga
      121 gggcggcggc gagcagaccg gagacggcca gcgtcttgcg cgacatacgt gttcctgttc
      181 gtgcgggggt gacatacccg tggcagacat gacgggggcc aacgccccca aatgatcatg
      241 actcccgaca tcgccccttg gttgtgcccc ggcccggacg agttcggaat gtccggtcgc
      301 gggcaccgtg cttcacgccg cgccccgctg gcgcacgacc gaaccggcgc gccccttcac
      361 cacctccagc tgcgcgtgca cccgtcggcg cagatcggcg acgtggctga cgatgccgac
      421 gctgcggtcg cgttcacgca gggagtccag gacgtccagg acctcgtcca gggtctggtc
      481 atccaggctg ccgaagccct cgtcgatgaa gagcgtgtcg agccgtacgc cgcccgcctc
      541 gtccgtgacc acgtccgcga ggccgagcgc cagggcgagc gaggcgaaga acgtctcgcc
      601 gcccgagagg gtcgccgtgt cccgctcgcg gccggtccac gcgtcgacca catgcagacc
      661 gaggcccgaa cggccgcgtc ccgtccggtc gtcggagtgc acgagggtgt agcgcccgga
      721 cgacatccgc cgcagccgga cggtcgcggc cgcggccacc tgctccaggc gggcggccag
      781 tacgtacgac tccaggcgca tcctgcgttc gttgtcggcc gaggtgcccg cggcgaggcc
      841 ggccatccgc gccacccggt cgtgggcggc gcgcagcggc gcgaggccgc gcgtcccggc
      901 ggcggtgcgg gcggagagcc tgtcgagttc ggcgcagcgc cgtgccgcgg cgtcgcgcgc
      961 ggacgcggcg gcccgaaggc gtctggcggc ggcctcagcc tcctcccgcg cggccggcag
     1021 gtcggcggga ggctgctgcg cggcggtggc cgtgtccggt tcggcgagga cggagcggac
     1081 cgcggcttct tcgttccgcc aggcgtcgag gcggtgctgg agttcgcggt ggcgggcgtc
     1141 gtcgaggagg gcgtcagccg cggcgaccgg cgtgtcgaat ccggcgcgga aggccgcgtc
     1201 ggcgaggcgc gcgtccgccg ccttgaggcg ctcggccgtc tcgtcggcga cgcgcacggc
     1261 gtccgcggcc tcggtgagca gggcggcctg ccgctccagc tgggcggcgc gggccgcgac
     1321 gcttccggtc gttccgcgcg cgtgggtcaa ctcctcttcc agggcgttct gttcgcggtc
     1381 gagggcctcg cgcagggtgg ccctcgacgc ggcacgccgg gcggcctcct gccggccggt
     1441 gactcggcgg tcgtactcgc gctcggcccg cgccagcgcc tcgcgcgcgg cgtgcagtcc
     1501 cgaggcgtgg tcgcgcgctt cggcgtgggc gcgccgcaac tcctccacgg cggcggcgag
     1561 ttcctcgaca ctcggctcgg tacccccggg cgcggactcg tccgcccccg tttcgccgct
     1621 tcgcgccgcc gctgtcgccg ccgccagcga ggcctgtacg tcgctcagtt cgcgctcggc
     1681 ggccgtgcgg gactccaggg cggcgcggtg ggcggacagc gcctcctcct ccgcgccgcg
     1741 gtccacgtgc ccggcgctct tgcgggcggg ggcggggtgt tccgtcgccc cgcacaccgc
     1801 gcacggttcg ccgtcggtca ggtgcgcggc gagttcggcg gcgatgccgg tgaggcgctg
     1861 ttccttcagg gcgagccagt gttcgtgcgt gctggtggcg tgttcgcggg cggtgagggc
     1921 gcgatcctgt gccgccgccg cgtcctgggc gagccggtcg cggcggcggg ccgcgtccag
     1981 ccgggtcctc accggttcga ggcgccccgc cagccgctcg gcgtgggtcg cggcctcctg
     2041 ggcggattcg acgcgctcct ggagggcggc ccgggtggcc tcccagccgt cgagccagcc
     2101 cgccgcgtcc tgcgacacct cgtcgtcggc gcgctcctgc cggtccaggg ccgcgcgctc
     2161 ggcggcgatg tcggcgagcc gctgctcggc acgccgcgcc gatcccaggc cgcccagctc
     2221 ctcggcggcc ttgcgcgcgg cggcggcgag cccggacgcc ccggcggctt cgaaggtgcc
     2281 ggggaggcgg ccacgcgcgc gtgtctcctc ctgcgcggcc cggcggtgct ccgcctccgc
     2341 ggcgtcgcgc agtgcgagcg ccggggcgac cgtctccgcc ttgcgcgccc gctccaggcg
     2401 ctgctcgcac tcgcgccgct cggcctcgcg cgcgtgcagc cgtgcggcgc gctcttgtgc
     2461 ctcggcgaac cggctctgca gccggtcgag ttcgcgtacg tcaccgagtc ggcgctccgc
     2521 ggccacctgc gcggattcgg cggcggtgag cgcgccgtcc gcgatggtga ggcgctctcg
     2581 ggccgtcgtg cgggcgacgg cggcccaggc gaggacttcg gtggcgaggc ccgggtcgcc
     2641 gggagcgagg tcgggcaggg gcagttcggc ttcccggccg tcttccgccg cggcctgctg
     2701 catgcggtgc gcgtcggcga ggagcgccgc gtcgccgtcc ttgacctcgg ccgcggtggt
     2761 gcgccgctgc tcgacgagcc gctgttcgac cgcggcgaac ctgcgggtgt cgaagagccg
     2821 cccgagcagc ttgccgcgtg cctccgcgtc cgcgcgcagg aagcgcgcga agtcgccctg
     2881 cggcagcagg acgacctggc agaactgctc cttgctcatg ccgagcagtt gggcgatctc
     2941 ctcgccgatc tcctggtggg accggctcag gtccttccag ccgccttccg gggtgctctc
     3001 gcggagccag ctctgggcct tctcggtggt cgtgccggtg cccctcttct tggggcgtgc
     3061 ccacggtggc tggcgggtga tctccaagcg gcgtccggcg acggtgagtt cgaggcacac
     3121 ctctgtgcgc gtgccctgct gcgcgtggtc gctgcgcagc gtcatgccct gcccgctgcc
     3181 ctggcgcgcg cccggcaccg atccgtacag cgcgtagcag acggcgtcga ggacggaggt
     3241 cttgcccgcg ccggtcgggc cgtgcagcag gaagagcccg gcggcggata gctcgtcgaa
     3301 gtcgatgtcc tgggtggtgc cgaagggccc gaacgcggtg acgcggagcc ggtggagtct
     3361 catcgggcga cctcgcgcag ggtgtcgtcg gcgcggaccg cgtcgaaggc cgaccgcagc
     3421 accgcccgct cgtgcccgtc ggggcccgcc ccgcgcacat gggccacgaa gtcctcggcg
     3481 atctgctcgt cgctgcggcc ctggagacgc tgggcgtacg agacgtccgg gtcgtccggg
     3541 gcccggtccg ggtcgaagac gaggctgagg gtgtgcggga agcgcgcgca gaggcgggcc
     3601 atggggtcgt cggggcgcac cgcgtcggtg agggtggcct cgacccaggc ttcctcgtgg
     3661 cgggtgaggc ctgggtcgtc gaggagttcg tcgagggtgc cgcggatacg ggcgagtgcg
     3721 cgcggcaccg ggcagtcgac gcgctcggcc tcgatctgcc cctcggggcc gaggtcgacg
     3781 agccacatgc tcttgcggtg gtcggcttcg gagaaggagt acggcagcgg ggagccggag
     3841 tagcgcacgc gcgtgccgag cgtctggctg ccgtgcagat gaccgagcgc cgcgtagtcg
     3901 acgccttcga agactccggc cggcaccgcg gcgactccgc cgaccgtgat gtcccgctcg
     3961 ctgtcactga tctgcccgcc gctgacgaac gcgtgggcga ggacgacgga gcgggtgccc
     4021 cgcgcgcggg tggcgaggtc ggcccgcacc cggtccatgg cggccccgat gaccgcctcg
     4081 tggcccgcct tggccacgcc gaactcgtcc ttcaccaggg cgggttcgag gtagggcagg
     4141 ccgtagaacg ccacgtcgcc gtggtcgtcg gcgaggagca cgggctccgc gcaggcggcg
     4201 gggtcggtgc gcagatggat gcccgcgcgg tcgatgaggc ccgcgccgac gccgaggcgg
     4261 cgcgccgagt cgtggttccc ggagatcatc accgtcggca cgccgaggtc ggcgagccgg
     4321 tgcagcgcgt cgtcgaacag ctccaccgcg gcgagcggcg gcaccgccct gtcgtacacg
     4381 tccccggcca ccaggacggc gtcgacctcg cgctcgcgcg cggtcgtcac caggtgaccg
     4441 atgaacgcgg cctgggcgtc cagcatgttc acgcggtgga acgagcggcc caggtgccag
     4501 tcggacgtgt gcagcagcct catgagcccc gagactaacg ggcgggtcgg acatcacggg
     4561 cggctgctcc tgtaaccgcc gccgtccagt gccccggctc cgcggggcgc gccgcgcgtc
     4621 aggcgtctcc gtacgcctct cccccgagtt cgaacaccgc gctgcccgcc gtggcgtcgg
     4681 ccagccagcc ccggaaggcg tccacgtcgg cgtccgggag accgatctcg atggtgaccg
     4741 cgtcgccgta acgaacgtca cgcacctcac ggcccgcggc acgcagatcg ttctggacct
     4801 tgcccgcgcg ctggtggtcg acggtgacgg tggcgaggcg gaagcggcgg cgggtgacgg
     4861 tgcccagggt gtcgagcgcc tcgccgaccg cgcctccgta ggcgcggatc agaccgcccg
     4921 cgccgagctt gacccctccg tagtaccggg tcacgaccgc ggcgacgtac cgcatgtcgc
     4981 ggcgcaggag catctgcagc atggggacgc ccgcggtgcc gcccggctcc ccgtcgtcac
     5041 tggccttctg gatcgccgcg tccgccccga tgacgtacgc gaagcagttg tggctggccg
     5101 tggggtgctc cttgcggacg cgtgcgacga agtcctgggc ctcccgctcg gtggcagcgg
     5161 gtgccagggc gcacaggaag cgcgagcggt tgatctcggt ctcgtgcacg ccctcgcggg
     5221 ccactgtgcg gtattcgtcc tgcatcacgc cagcgtaggc gctcctcggg agacgccggt
     5281 ggccgggagc ggtgccgagt ggcacaggtc actgtccacg cgcgcgtgcc gtgcgccggg
     5341 taccgtgatc tctcgtgacg tcaccctcga tatccgtgcc ccaagtcccg gaagcctcgg
     5401 gccccttggc atccctgctg gccgccgtgc ctgtcaccgt cgtcgagact tatggcgacc
     5461 cggccgacgc cgtgctcttc ccggaggagg aggcggtcgt ggcgaaggcg gtggccaagc
     5521 ggcgcgatga gttcaccacc gtgcggcact gcgcccgggc cgcgctgcac ctcatcggcg
     5581 tgccgccggc cccgatcctg ccgggccagc ggggtgcgcc ccgctggccg gacggcgtcg
     5641 tcggcagcat gacgcactgc gccgggtacc gtgcggcggt cgtggcccgc gccggtgagg
     5701 tgacctcgct cggcgtcgac gcggagccgg gcgagccgct gcgcgacccg gacgtgctga
     5761 ccatgatcgc cgacgagtcg gagcgcgcgg cgctcgccgc cctcggcgcc cgccaccccg
     5821 gcacaccctg ggaccgcctg ctcttcagcg ccaaggagtc ggtctacaag acgtggttcc
     5881 cgctcaccgg gcgctggctc ggtttcgagg acgcccgggt gcggctcgac ccggacggga
     5941 cgttcacggc gcggctgctc gtcgaggggc ccgtggtgga gggcgtggag ctgaaggtgt
     6001 tctcggggca gtggatcgtg cgcgacggga tcgccgcgac ggccatcgtc ctgccgatca
     6061 ccactcctgc cgatccgtcc tccgctgttc acgcgtaggc ctccgtcaga cataacggct
     6121 ataggagaca tcacgcgcat tcagggagcc gctgcccggg atgaggccgc tgcccggtac
     6181 gtggggcggc ctccgagcca ggtgccccgc acgcgcgcgt ggcggatcgc catcgggtcg
     6241 gcggtgcgtg ggtcggcgga gagcaggacc aggtcggcgg gggcgcccgg cgccaggcgc
     6301 agccggtcgt cggcgcccgc ctggtgggcg accccggcgg tggccgccgt cagcgcctcc
     6361 tcgacggtca gccgctggtg ggggatccag ccttccgccg gctcccccgt gaacgtacgc
     6421 ctggtgacgg ccacttggat gccttccagg gggatgtgcg agctgacggg ccagtcgctg
     6481 ccgaaggaga gccgcacgcc gtcccgcgcc agctcgccca tggggtattg cagggccgcc
     6541 cggtgcgcgc cgagccgcgg gatggacagc tcggtctgga gcgggtcggg ctgcgcccag
     6601 aggggttcga agttggcgat gacaccgagc gcggcgaagc ggggcaggtc ggcggggtcg
     6661 accagctgga catgggtgat caccgggcgc cggtcccagg cggggttggc gtggatcgcg
     6721 gtctcgatcg cgtcgagcga ggcgcgtacg cccgcgtcgc cgatcgcgtg aatgtgggtc
     6781 tggaagcccg cggcgtcgaa ggcgcgtacc gcctcggcga gcgcgcgagg ttcccacacg
     6841 ggcatgccgc agctgtgcga cgcgtccagg tagggggcga gcatggcggc cgtaccgccc
     6901 tcgatgacgc cgtcgctgaa gaacttcacc gtccgcgcgg tcagcagctc gccgccctcc
     6961 gcggccaccc gcgcgcgtgt ctcggcgaac ggcgcgagct gcccgcgcca ccggtcggga
     7021 tccgcgcgct gggcgaggtc gacccggaag gccagggcgt cacgccgggc ggcggtgaga
     7081 taggcgtcgg ccatctccgg ttcgacccag gcgtcctgca cccaggtgat gcccgcgcgc
     7141 gcgtacgcgt gcccggcgcg gcgcaccgcc tcgacgagtt cgtccgtggc gcgcgagggg
     7201 acctggtcga gcacgaggtc gcaggcgtgc cactcgcgca gggtgccgag cggtgtgccg
     7261 tcggggcggc gcacgatcca gccgaggcgc ggctccggag tgctctcgct caccccggcc
     7321 ctgcgcagcg cctcggtgtt gcaccacacg gtgtggtagt cgtgggcgcg cagcacgacg
     7381 ggccggtcgg gcaccgccgc gtcaagccag cgcgcgtcga actccccgtc gggcgcgagc
     7441 gcggggtcgt aggaggcgcc gacgatccac tcggcctccg ggtgctcccc ggcccaccgc
     7501 ccgacttcgg agacgatcgc gtcgacggag gcgagctcct tgatctgcgg cccgaagctc
     7561 tccaggccgc cgaagagcgg gtgggcgtgg ccgtcgccga aggcggccat cagcagtccg
     7621 tcgccgatgt cgacgacctc gtcggcggtg gcggcgaggg cgcgggcctc gtcgccgagc
     7681 gccaggacgc ggccgtcgcg cacggcgagc gccgtggtgt cgtggtgggg gtggctcccg
     7741 gttcgggtgg tgccgaggaa gaccagggtc gtcatgctgt cggtttctcc ttgcttgcct
     7801 actcgcctac tcgactgctc gcttgctcgc ggccgctcgc ggtttccgcc accctccgcc
     7861 acccctcaga cgctctcggc gtccaccgtc gtcagccgct cgtacgccat cggatcgcgc
     7921 gccttgacgc gcagcgccag catggcgccg acgacgaaca gcaccggcag cgggaggatc
     7981 agggccgcgt tcacaccggt ggaggcgccg gtgagcagat cgaggtgggc acagaccagg
     8041 acgatcatga cggcgagacc cgcgcaggcg agcaagggag cggcgaccac ccgccaggcc
     8101 ggcagcgcgc gccggtcacg gcggaagaac ccgtacacgg cgagggcggc gagtgcctgc
     8161 atgagcatca cgccgaggat gccggagccg ttggtccaca ggaacgtgac ggtgtacgga
     8221 tcgaccccgc tgaccaccgt cacgacgatc accgcgagcg cgagggccga ctgcgtgagc
     8281 acggccgcgg ccggtgcccg ggtcttcgcg gagaccgtgc cgaggcgggc cgggagcagg
     8341 ccttccctgc cgagcgcgta gaagtagcgg gcggcgccgt tgtggaaggc gagcgtggcc
     8401 gcgaaggcgc tggtgatgat cagtacgtgc atggagtcgg cggcccaggc cccgctgaag
     8461 cgctcggtgg cggtgaagac catgtcggcg ccgccctctc cgttcgccac ggcctgggcg
     8521 cggtcgccgt acgcgttgat gatcatccag acggtgaagg tgtagaagag cgcgaggaac
     8581 gccacggcga tgtaggtggc gcgcggcacg gtcctctccg gtcgccgtgc ctcctccgcg
     8641 tagatcgcgg tcgcctcgaa gccgacgaag gcgccgatgg cgaggacgaa catgccgccc
     8701 gccccggacg cgccgagatg gccgggtgac agcgccccca ggtcgacgcc ccgcgggccg
     8761 ccgccgtgcg cgaggacgcc cgcttcgaag gcgagcagta ccagcacttc gaggaccagg
     8821 gcgacgccga ggaccttggc gctgagggtg accctgaggt agccgagcgc gccgatggcg
     8881 accagtccgc ccgacgccca gacccaccag ggcacatggg ccccggtaag gtcctcgaag
     8941 cccgactccg tgaaccatcc gaaggcggcg agcagtccca cctcgatcgc gttgtacgag
     9001 aagagcgcga cgtacgcgga gccggctccg gccgggcggc cgagccccct gcctatgtac
     9061 gcgtagaagg cgccggcgtt gcgcacgtac cggctcatgg ccgtgaaccc ggcggcgaag
     9121 acgatcagga gcaggcccga gagcagatag ccgagcggtg ccgcccggcc cgccatgccg
     9181 atggccagcg gggccacgcc cgccatgacc gtcagcgggg ccgcggccgc catgacgaag
     9241 aagaccagat cgccggtgcc gacggccccg ccgctgaggc cgtgggagga gggaggggag
     9301 gtcggtacgg agggaggcgg tacggaggag gggggtgcgg tcacgcgcgt actcccgagg
     9361 tcggagacgc agagaactaa accgcttcgg cgagggcgtg ggaaggggcc gtgaaatcga
     9421 tccactcgcc ccgacgacgg tcggaggagg tggagaaggc ggaaacaggc caagaagtgc
     9481 gaggagcggg agcacgcgca cccgagccga atgcgccccg gcggctcccc cctcgccccc
     9541 tctgccggcc gctccgcggc aggacaaccc cactgcggcc gatgcccagt tcaaaacgtt
     9601 ttttcccttg tgcacacatg cgtcattgag ttgcgcactc gttgattaaa cccacaagta
     9661 gcaacgcgtt cacacaccgg catatgcgtt tttcctattg tcatactttc tgtcatggtc
     9721 ttgcagcatc ttccggttat gcacatagct gggtgctgcg acctttcccg tcccgggttc
     9781 ccgatgagcc cgggacaggc cgacggagcc cccgcgcgcc gtcgaccagg gaagcggtcg
     9841 tcacctctat ccgaggagac gtcatgaaga aggcctacga agctccgtcg ctcgtccggc
     9901 tcgggacgtt ccggaagaag accgggctgc tggcgcggtc cggaaacgac cgactcattt
     9961 tcagcaagaa ctgacgaccg aaggtttctg acccgacgtc atgactgaac tgcacgagag
    10021 tgcggggacg ggccccggcg acgcgcactt cacggtcttc aacgaccgtg cggacgcggc
    10081 cgccgtggcc cgctccttcg cccacccagg aacacgtgtc ctcaaccatt cctcgggccg
    10141 gccgtggctg gtcggccagt gggccgacga agagatcgtc acggcgcgcg tcggccgcgc
    10201 cgccctggcc gtcatcggtt gctgccccgt caccaccgcc gaactggagg cccgggcagg
    10261 gcggttgcgc gacctgacgg agctggacgt gtgggcccgc tccctgcccg gcagcttcca
    10321 ccttgtcgcc gccctggacc agcggctcag gatgcagggc accgcgtccg ggctccggct
    10381 ggtcttccac gccaccgtgg acggtgtgcc cttggccgcc acccgcgccg acgtcctcgc
    10441 cgccgccctg ggccacgacc ccgacgaaga acagctcgcg atccggctgt tgtggcctgc
    10501 cccctatccc cttttcgaga cctccctctg gtacggcgtc accgcggtgc ccccacagga
    10561 cgcgctgatc gtcggcgcgg acgggcggac cgtgcaccac tcacggtggt ggaccccgcc
    10621 ggagccggtc cgcaccctcg ccgacggggc gccgctggtc cgcgaggccc tcgccacggc
    10681 catcgacgcc cgcacgcgcc aaggcggcgt ggtcagctgc gacctgtccg gcggcctgga
    10741 ctccacctcc atctgcttcc tcgcggaccg gtcccccgcc aaggtggtgg ccagcacctg
    10801 gccgggacgc gacccggccg acaccgacct gcactgggcc gagcgggcgg tgaaacacct
    10861 cccggacgtc gagcatgtgg tgtgggacgc gcacgcctca ccgctggtct acgacgatct
    10921 gctgaacatc gacgacctgc tggacgaacc gaccatcggc gtcatggacc gctcaagggt
    10981 gctgagccat ctgccggaca tggcccggcg gggcagccga gtgcacatga cgggcatcgg
    11041 cggcgatcac gtggcctggt gctcggaggc gtactaccac cggctgtcgc gcacccgccc
    11101 gctgttcgca ctgcggcagc tgcggggctt ccgggccctg tggcagtggc cgctcggtac
    11161 gacggcccgt gccctggccg attcccggcc gtacggcagg tgtctcgccg acgccgtcgg
    11221 acacctgcgc gacccgctcc cggcatcggc caccaccagt ctcggctggg gcatgccccc
    11281 acgtctcttc gagtgggtca cgcccgacgc cacgcgcatg gtcgagcggg cgctgcggga
    11341 ggccgcttcg acggtcgtgc ccctgcaccc cgaccgtggc atgcacgccg atcttgaaca
    11401 gatccgctcg tgcacgcgca tcatccgcca gtgggaccgc atggcggccc gcgtcggtgt
    11461 cccgatggcc tcgccgttcc tcgacgaccg cgtcatcgag gcgtgcctcg cgatccggcc
    11521 cgaggaacgc gtcacgccct gggcgtacaa acccgtcctc accaccgcga tgcgcggcat
    11581 cgttcccgag gagtgcctgc ggcgcaccac caaggcggcc gccgccatgg acgccgccga
    11641 cggactgcgc aagcaccgcg ccgacctgct ggccctgtgg gaggactccc ggctggagcg
    11701 gctcggcctg gtcgacggtg agacgctgcg ccgcctcgcg cagcggccct ccgcgcccgg
    11761 gctgcgcgac ggcatcctct actcgaccat cgccgccgag gtatggctcc gcggcctctc
    11821 ccccgcccgc acccgatagg cccgccaccg gagaaaggca gtcacccacc atggcactgc
    11881 agttcggccc cgatgtctcc accacggaga ccgactacgg cacggtcctt ctcgaccagc
    11941 gcagcggaaa ctactgggaa ctcaacccca ccgggagcct cgtcgtgaag accctcctcg
    12001 acggcggcga ggaggcggcg gccatcgacg cgctcatctg cgagttcgac atcgaccggg
    12061 ctcgcgcgca gcaggacgtc accactctcg tacgggaact gcgggacgcg gggctggtct
    12121 catgacgaca ccgagcgccc tggagcggcc cacgggtgtc cccttcaccc ggcgtctcgc
    12181 cgcccgactc gtgctgctgc ccgccgtcgc gctctccttg ctgcccccgc gccggatccg
    12241 caccgtcctc ggtgtcgtac gccgtggcgc cgccccggcc accgccgcgc aggcgaagaa
    12301 ggcccgggac gcgatgtgcg cgaccagcct gctctgcgcc ggcccgaaag gctgtctgcc
    12361 ccgctcgctg ggctccgccc tgctgtgccg actgatgggc ggctggccga cgtggtgcac
    12421 gggggcgagc gtggtgcctc ccttcaacgc gcacgcctgg atcgaggcgg agggccggcc
    12481 catcggagag gagatgcccg acgactactt cgcgcggctg ctctcggtgg gaccggcggg
    12541 aacttctcgg gccgggtgct agtttctaca gtgttgtagt ttctacgctg ctgtagaaca
    12601 cccgatatcg atatgtgcat ggagttcccc atggccctgt gggaccgcgt caaggaatcc
    12661 gcgtcgacga tgcagaccca gctgctggcg aagaagaacg acctcaagag cggcgccttc
    12721 cgcgacgcga gcatggcgat gtgcgccctg gtggcagccg cggacggcac ggtggacccg
    12781 accgaacgcg cccgcgtggc ccagctcatc ggtgcgaacg aggtgttgca gaacttcccg
    12841 gcggacgacc tgcgccgccg cttcgacgcc tacgtcgaca agctgaccgc cgacttcgcg
    12901 ttcggcaagg tgagcgttct ccaggaggtc gccaaggcga ggaagaagcc cgcggaggcc
    12961 cgcgcggtca tccagatagg catcgtcatc ggcggcgccg acggcgactt cgacaaggac
    13021 gagcaggccg tggtgcgcga ggcgtgcttc gcgctggacc tgccgccgca cgagttcgac
    13081 ctgtaacggc gccggcacgg ggcccgttca cagcggcgca ggctcggggc ggcgcccgtt
    13141 cacagcggtg tggccgcccg caggatgagg accatcgtga ccgcggagtt cgccgaggac
    13201 atcgcggaga cgacggtgcc gaacgcggcg caccacaggg cgagtcccac cgcggtgaac
    13261 agggagggac gcgtgcgggc ggcgggcgcc ggggcgagca gggcggcgac gcggcgcggc
    13321 acgggccccg gcgtggcgaa ccccgcgagg gcgggcgcgg gcgcgccccg ggagaccagg
    13381 gcggccctgc cgatcgcacg ggcgacgacc cgcctgtccc gtacggcccg tgccgccgcc
    13441 tcgtcggccc accgttccgc ggtgaaggcg acggaggtgc gcagcgggcg caggaagggg
    13501 ttggcgcggg ccgccaactg cgtgacgagg aggtgacggt ggtgccgcgc ggtgagatgg
    13561 gcccgctcgt gcgcgaacag cgcgcgccgc tccggggcgg cgagccggtt cagcatgccg
    13621 gtggtgacca cgacgcggcc gccgtcgcgc gccggaaggg cgtaggcgta cggagcgtcg
    13681 tcggggagca ccgcgacgga cgtgccgggc agcccttcga gggcgcgccg ccctcgaagg
    13741 cgtacgcgcg cgtgccgcca cagggtgcgg gcgcaggcgg cgcacacggc gagcagtgcg
    13801 gggatggcgg ccttccccgc gacctcgtaa taggggacgg cggcccgcac ctcggggtcg
    13861 gaccaggcgt ccggcagggg gttgcccggc agttgggcgg tgccgacgac catgaggagc
    13921 gcgagacaga gcgtgctgca cagggccatc accccggcga cggaggtgag cacgcgcgtg
    13981 gcggtgcgcg ggtggaggtg atgctcggcg aggcgggcga ccggccaggc ggtcagcggc
    14041 agcacgaggg gcaggaagac gaagacgccc atcaggcaga agctcccatc gggtgtcagt
    14101 cgtccgtctc ggcgcccgcc cgcccgagca actcgcgcag gagctgttcg tcgtcgggcg
    14161 tcagcgtcgt gacgaagctg gcgaggaccg cttcccggtc gctctcgccg tcgagcacct
    14221 tgcgcatgcg gaaggcggcg agccccgcct cgtccgacgc ggacgtccac gcgaaggagc
    14281 ggcccgcgcg ctcccgggtc accacgtcct tggcgaggag gcgggtcagg atcgtcatca
    14341 cggtcgtata ggcgaggtcg ccgccgatcc gctcctgcac ccaggcggcg ctgaccggtc
    14401 cgcgggcggc gtgcagcgcg gcgaggacct gctgctccag ctcgccctgg gcgcggcggc
    14461 gcaggcgcgg ccggcgctcc tcgcgcttgt cgtggtgctc catgcccggg ctccctccag
    14521 cctgttcgtg ctcctcggcg gccgggagcg ccatatcgta acggcccctg accaccccac
    14581 ccgcttctac attcctgtag attctacgga accatcacca gaaacgcgtc actcggatct
    14641 caggaggaca ttgtgggagt ttccctggcc aagggcggca acgtctcgct cagcaaggag
    14701 gccccgggcc tcaccgccgt actggtcggg ctgggctggg atgtgcgcac cacgacgggc
    14761 acggactacg acctggacgc cagcgcgctg ctctgcgacg actccggcaa ggtcgtctcg
    14821 gaccagcact tcgtcttcta caacaacctg acgagcccgg acggttcggt cgagcacacc
    14881 ggtgacaacc tcaccggtga gggcgagggc gacgacgagg cagtgaaggt gaacctcgcc
    14941 caggtgcccg accagatcac gaagatcgtc ttcccggtgt cgatccacga cgccgagaac
    15001 cgcggccaga gcttcggcca ggtccgcaac gccttcatcc gcgtggtgaa ccaggcggac
    15061 ggcgtcgaga tcgcgcgcta cgacctctcc gaggacgcgt cgacggagac cgcgatggtc
    15121 ttcggcgagc tgtaccgcca tggtgccgag tggaaattcc gcgcggtcgg ccagggttat
    15181 gcaagtggac tgcggggcat cgcgacggac ttcggcgtga acgtctgacc cgcgctccct
    15241 gacggcatcc ggccgcgaac tcgaggaggc aggtcatgta cggcgaccag aagacggtgc
    15301 gcaagatcct gacggagctg ggcgacacct gggccgtcgt gggcctgtcc gacaaccgcg
    15361 agcgggcggc gtacggcgtc gcggccgttc tgcggggctt cggcaagcgt gtcgtgccga
    15421 tccaccccaa ggccgggacg gtccacggcg agcaggggta tccgtccctg tccgccgtgc
    15481 cgttcgagat cgacgtggtc gatgtgttcg tcaacagcgg cctagcgggc caggtcgccg
    15541 acgaggcggt ggcggccggc gcgcgggcgg tctggttcca gctcggcgtg atcgacgagg
    15601 cggcgtacga acggacgcgc gcggcgggcc tggacatggt catggaccgc tgcccggcca
    15661 tcgagatccc ccggctgggc tgagagacgg cgcgggccgg gggcgacggc gtcctcggcc
    15721 gcgtccccgt cctcggcctc agaactgctt cgagggccag tcgagcaggc gcgcgccgat
    15781 cacggcggtc tgcagtgtgt aacggtgcac ggggtccgag gggttggccc cggtcagtcc
    15841 gtggatgcgt tccagccggt aggtcagggc gcgcacgctc agcgtcagtc ggcgggccgc
    15901 ctccgccgcg acacaccccg agtcgaagta cgcggcgagc gtgtcgatga gcggctgcgc
    15961 tccgccgcgg gcctggcgca gcgggccgag cgtgttgagc acgaggtcgg ccatggcctg
    16021 ccggtcgcgg gtgaggacgg ggtagacgag caggtcggcc gcgtgcagca cggggtcgtc
    16081 gagctccagg cgcccggcga gatcgagggc gttgagcgct tcctcgtacg actggacgac
    16141 gccgccgggg ccgggctgcg ggcggccgat ggcgacgcgg ccgccgtcgg tgacggcgta
    16201 cgcgtgcttg gcgaagaagg tcaggacctc gtcctggtcg ccgggggcga cgcacaccag
    16261 gcggccgtcc ttggtggtga gcaggatgct gcggtcgccg aaccggccga tcagggcccg
    16321 ctcgacctcg cgggggaccg cgtgcccctc ctcgtatccg tcggggccct cggcgacggc
    16381 gacggcgtgc tcgtaggaga ggcgcagtcc gaagcgttcc gcgcgctcgg cgagcaggcc
    16441 gaggtcgctg cgtccgtaga gcaggtcgtc gatgaactcg cgccgggccg cctcctcctg
    16501 gcgtacggcg aggcgctggg cgcgttcgta gccctcggcg aaggcgtcca tggcctgctc
    16561 ggcggcggcc agggcgcagt cgacggagag cgcgcgctcg gcgggccagt gggcgcgggt
    16621 cgccgcgagg tgcgcgccca ccagggcccg gaggccgaaa ccggcgtcgg cggcccgctc
    16681 ccccagcacg cgccgtgagg ccagctcatc ccgggtgagc cgacggcccg tcgacgaggc
    16741 ggcggcgagg atgtgggcat agccgtcgag gtactcctgc ggtatgtcct gccccgccat
    16801 gccgccccct gtcgtcctgt tgccgttgaa ccgttgatgc ctttttaacg catggcgcac
    16861 cggcgggcga cggccgggcc tgcccggcgc tccggggcac gggcccggaa caatcggctc
    16921 gcccggaccg ttggacaggg catgcctttg actggagagt acgaacccgg cacgtgggac
    16981 tgggccacca agcagaccga gttgtacgag agctcgggcg gcacggaggg cacgactctg
    17041 aggggcaagc ccgtcatcgt gctgacgtcg atcggcgcca agagcgggaa gctccgcaag
    17101 aaccccctga tgcgcgtcga gcacgacggg gagtacgcgg tggtggcgtc gaagggcggc
    17161 gaccccgcga acccgtcctg gtaccacaac ctcatcgccc acccgcatgt ggagttgcag
    17221 gacgggccgg tgaagaagga ctaccgcgcg cgggtcgtca ccggcgagga gcggcggatc
    17281 tggtgggagc gggcggtcgc ggtgtggccg gactacgacg actaccagaa gaagacggcc
    17341 cgtgagatcc cgctcttcgt cctgacgcct gtcgagtcct gacgcccgtc gggtcctgac
    17401 gcccgtaaag tcctgacccc tcgtcacccg gccgttcgct gtccgctccg gccccctggg
    17461 agagccccgg cggccggagc gcacggcgtg cggctgacgc gccggggtcg cgtcaggact
    17521 cctgttggcg tcgacgggcc cggtaggccc gcaggttcgc cgcgttgccg catgtccgca
    17581 cgtcgtgcca gacgccgctg ttgttgcggg agcggtcgta gaacgcgact cggcagagcg
    17641 ggttgcggca ggtcttgagg cggcgcgcgg tgtccgtctg ctggccttcg tacaccgccg
    17701 cgagggccag tgcgacgagg tgggcccctc cggtgccccg cggctccagg cgtacgacgc
    17761 cgtcctcacc gagccgtagc gcggcctctc cggagtacgc gccgcccggc ccgaggcccc
    17821 cggccgcctc gccctgctct tgcccctgcc ccgcgacgag cttgcccagc gtctcgcgga
    17881 acgaccgcag ctcgcgcagg ccctcggcgt caagggtgac gcgcggcgct ggctgcccgg
    17941 tggccgaagt ccactcggcg acgacctcct tcgcccactc ctgcgccgag gcgcgcccgt
    18001 cgagcaggtc ggggtgcggg ggcgcgccgg cggcgacggt gttgagcagg tcctggacga
    18061 gtccgaggcc gccgggcgcg gcctccaggc ggtaccgcgc ggtcgcgggc caggtcatgg
    18121 cggatcactc tccggggttc gaacggggcg ccccactctt tcacgcgagg ccgcgcgccc
    18181 cgctcacacc agggcgtcga ggagcgaggc gtcgtacggc accgccttgt ccaagcggcc
    18241 ggtgagcgcc ttgacgggcc agccggggtc ggcgaccaac gcgcgtgcga cggcgacgag
    18301 gtcgaactcg tcgcgttcca gccggtccag gagcgggtcg ataccggtga cgccggaccg
    18361 ctgtgcgcgc cccggcgccc cggcgaactg ccggtcgaga ccgacggagc ccacggtgat
    18421 cgacggcctg ccggtgagct tcttcgccca gcccgcgagg ttcaggtcac tgcccgcgaa
    18481 ctcggggagc cagtagcgcc gcgtggaggc gtggaaggcg tccacaccgg ccgccgcgag
    18541 cggggtgagc agctgctcca gctcggccgg gttctcggcg acgcgggcct catagtggtc
    18601 ggtcttccac tgggagaggc ggaagacgac cgggaagccg ggtgagacca ccgcacgcac
    18661 ggcggcgacg atctcggcgg cgaaccgcgc gcgggaggcg tggtccccgc cgtaggcgtc
    18721 accgcgggtg ttcgtgccgt gccacaggaa cgcgtcgatc aagtagccgt gcgcgccgtg
    18781 cagttcgacg ccgtcgaagc cgatgcgctc ggcggcggcg gccgcctcgg cgaaggcctc
    18841 gaccaccgcg tcgatgtcgt cgagcgtcat ggccctgccg tgcgggcgcc cgtcgaggtc
    18901 gatccccgag ggcccttccg cgggtacgcc gagcggcggg acggcgtcgg tgcggagcac
    18961 gcccgtatgc cacagctggg gcatgatccg gccgcccgcc ccgtgcaccc gttcgaccac
    19021 cctcgcccag cccgccaggg ccttctcccc gtggaaatgc ggcacgcggt cgtacgcggc
    19081 cgccgcgtcc cgccccacgt aggtgccctc ggtgacgatc agcccggcgc ctccggccgc
    19141 ccgccgcgcg tagtacgcgg cgacgtcctc accgggcact ccgcccggcg agaagcgtct
    19201 ggtcacggcg gccatcgcga tccggttgcg cagcgtcaag tcacccaggg cgaagggctg
    19261 tcccagcagg cgtgcggcac gggaccgcga atcgagggcc gtgtccgtaa ggactgaagg
    19321 ggccgaaggg actgaagggg cgttaggggg cgaaggcgtc gcgtcggtct tctccatcac
    19381 aggctcctct gccttgcata cgtgatcgtc tcgcgcaggt gatcgtcttg cgtgcgaaat
    19441 caacgaaaga agcgtaactc atttacctct gtcgccctgg ctccaggacg tgacgtgcgc
    19501 cgcaaacggc gtccgggtgt tgtgggggtg cggccggaac tgatcaggtg cgctcatgac
    19561 gaccgggtac ttcacgtccg tcgacgaggt cgcggtccgc ctggcggagg ccggatatct
    19621 ggcctcgccc gcggtcgcca ccaccgtctt cctcgccgac aggctcggca agccgctgct
    19681 cgtggagggc ccggccgggg tgggcaagac ggagctggcg aaggccgtcg cgcaggtcgc
    19741 gggcgcccgc ctgatccggc tccagtgcta cgagggcgtg gacgagtccc gcgcgctcta
    19801 cgagtggaac cacgccaagc agttgctccg catcaccgcc gggcgcgacg agtcgtggga
    19861 cgagacgcgc acggacatct tcagcgagga gttcctgctc tcgcgcccgc tgctcacggc
    19921 gatccgcggc accgagccga aggtgctgct gatcgacgag accgacaagg cggacgtcga
    19981 ggtggagggc ctgctcctcg aagtcctcag cgacttccag gtcaccgttc ccgagctggg
    20041 cacgatcagc gcggagcggc gcccgttcgt ggtcctcacc tccaacgcga gccgggagct
    20101 gtccgaggcg ctgcgccgcc gctgtctgtt cctccatatc ggcttccccg aggaggagtt
    20161 ggagcgccgc atcgtccgga tgagggtgcc gggcctggac gaggtgctcg ccgatgcggt
    20221 ggtgcgggtg gtgggcgcgc tgcgcgccat ggatctgcgg aaggtgccgt cggtcgccga
    20281 gaccatcgac tgggcgcgca ccctgctggc gctcggtgtc ggcaccctgg acgagacggt
    20341 cgtacgcgac agcctcggcg tcgtcctgaa gcaccaggac gacgtactga aggcggcagc
    20401 caagctggac ctggacgccg tgtgagggcg ctccccgacc ccggggcgcc cgctgccgaa
    20461 gaggccggtg ccgaaggggc cgccgccgca gaaacccgcg ccgtggagac ccgtgccgag
    20521 ggggtcaccg gcaggctcac cggtctcgtc agggcgctgc gctcgcacgg tctgcggatc
    20581 ggcccgggcg agaccgtcga cgcggcggcc gcccttgaag cgctcggcct cgccgaccgc
    20641 gagcgggtca gggaagggct ggccgccgcg ctgctccacc aggagagcca gcgggcggtc
    20701 ttcgatcccg tcttcgagct gtacttcccg ttgggcagag gtgtctcggc acaggagggc
    20761 ggcgccgagc ccgaccggga ggcgctgcgc gagcgtctgg tcgccgcgct cgctgcggac
    20821 gaccaggcgc tgctcggccg gttggcgcgc gaggcggtgg acggcttcgg cgggtacggc
    20881 tcggcgcagg ggtcagacgg ctggtcctcc caccagacgc tgagccgcct gcggcccgag
    20941 acgcttctcg cgcgtgttct cgccgctctg cgcgcggggg ccaccggcgc tcccgagggg
    21001 gccgccgcgt tcacggaccg gcttgagccc gacgagatcc ggcgccgcat cgaagggttc
    21061 cgcgagcgcg tccggaccga ggcgcgccgc cgggtcgccg agcggcgcgg caccgaggag
    21121 atcgcccgcc gggccgtggc gaccagcgcc gaccgggtcg acttcctgct cgcgggccgc
    21181 gcgcagctcg acgaactgcg cagggccgtg tatccgctgg cccgcaaact cgcgacccgg
    21241 ctcgccgccc ggcgcagacg ggccgcacac ggcagcatcg acctgcgccg caccctgcgc
    21301 ggctccctgt cgaccggcgg tgtgccgatg cggccggtgc tgcgccgccg ccgtcccgca
    21361 cggcccgaac tggtgctgct ctgcgatgtg tccggctcgg tggcgggctt cgcgaacttc
    21421 acgatgctgc tggtgcaggc gctgcacgac cagttcagca aggtgcgcgt gttcgcgttc
    21481 gtcaaccgtg ccgacgaggt gaccgggctg ctcgcgcgcg gctccgcgga cccggcgggc
    21541 ctcggcgccc gcatcctcgg cgaggcagcg gtgaccggct ggcacggcag cagcgactac
    21601 ggcacctccc tctgcgagtt cgccgagcgc cacctcgacg cggtcggccc gcgcaccacg
    21661 gtcttcgtcc tcggcgacgc ccgtacgaac atgagcgacc cgaacctccc ggcgctgcgg
    21721 cagatcgccg ggcgggcccg ccgggtgtac tggctcaacc ccgagcagcg cgcgcagtgg
    21781 tcgaccggtg actcggcggc gtacgcgtac gcggaactgg tcgagatgca cgagtgccgc
    21841 aacgcccggc agctcggcga gctgatcgcg cggctgctgc cggtgtgaga cgcggcacgg
    21901 ggcggcaacg gcccgcgcgc ggcgggcgac gcccggtcag gaccggtcag gaccggcagc
    21961 caggtcgtca ggaccggtca gcccccgccg ccacgtcgtc ggcgatggac ttgtccaggg
    22021 cggcgcgcac cagcgccgcc gacagggccg cggggtccgt gtccccggcg aggcgcagca
    22081 gttcctcctc gtcctcgggc agaccgagcc ggcccgcgcc ttgcagcgcc ttgccgccca
    22141 ggcggggccc gacccgcggc cacacccgct gcacctcgcg caggaagatg tccgcgcccg
    22201 tcgggccgag accgggcacg gtctggagca ggcggcgcag cgcggcgtcg gtgtcggcgg
    22261 cgtcccgcag gcggcgcaga tcgcccccgt actcccgcag gaccagctcg gcgccctcgc
    22321 ccagctgggt ggaggtgctc tcgtcgtagc ggcggtaccc gccgcggccc agcgcgtcga
    22381 cccgccgctg ccacgacgcg tcggccatgc gccgcgggtc acgcaggccg gcggcgaaca
    22441 gctcctgggc ggcaccgacg gccgcggcgg cgcggatgcg ggcgctcagc agtacggaca
    22501 ggacgaggag ttggtacagc ggctgcgggg tgtcccgcag ccggatgccc gcctcctcgg
    22561 cg
//
