LOCUS       NZ_CP029618            22814 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 06738 chromosome, complete genome.
ACCESSION   NZ_CP029618
VERSION     NZ_CP029618.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 06738
  ORGANISM  Streptomyces sp. WAC 06738
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8324535)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8324535)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. Jun-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 148.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945505.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 05:01:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,191
            CDSs (total)                      :: 7,115
            Genes (coding)                    :: 6,917
            CDSs (with protein)               :: 6,917
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 107 of 198
            Pseudo Genes (incomplete)         :: 115 of 198
            Pseudo Genes (internal stop)      :: 5 of 198
            Pseudo Genes (multiple problems)  :: 27 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:28:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6943537
            Orig. end                         :: 6966351
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029618.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22814
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="19"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22814
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22814
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12814](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12814)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(191..206)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.01"
                     /tool="antismash"
     misc_feature    256..270
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(458..1201)
                     /locus_tag="DMB38_RS30335"
                     /old_locus_tag="DMB38_30325"
     CDS             complement(458..1201)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837050.1"
                     /locus_tag="DMB38_RS30335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30325"
                     /product="hypothetical protein"
                     /protein_id="WP_125937824.1"
                     /transl_table=11
                     /translation="MSEPILVLVSAAAGLVVGAALGWYARGSLVGRRHRRRERFFGLPR
                     NSEALVVVNRDAGGGDWSVAKHDALALLELSAVIKSCGAHAQVVAQDTAQQTFGDRTEF
                     CVGTPISNRRMAAHMQSLLPGVRINTDPEPGPDRGAFAVGTERYRLENGVSEHVLLARL
                     SAGQEARPVFLSCGQRSITNQAAMRYLVKNESRLNRKYGSNSFVLLLKVVNSQSYGPDV
                     VELVGDVTKQAQTPLAQPNGKHGKS"
     misc_feature    1224..1240
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.45"
                     /tool="antismash"
     misc_feature    1372..1385
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            1471..2730
                     /locus_tag="DMB38_RS30340"
                     /old_locus_tag="DMB38_30330"
     CDS             1471..2730
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837051.1"
                     /locus_tag="DMB38_RS30340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30330"
                     /product="hypothetical protein"
                     /protein_id="WP_240662549.1"
                     /transl_table=11
                     /translation="MPAPWDVVESLLHDLAEHAGRRTADAALPRARDLHRAAVAAHDAR
                     SPDPAALTAVLRARLAEHRTAEEDVERLRDRLAVERNPWTAEQLEYELAWVRDDAARAA
                     ARCAELRGRIEALARQAAGREPAPPPPAALRGARFAGAASAPPPVLPAVGGAYEGVPPD
                     AAEAGAAEPPPPRGARFPGPGTEGAGGPPAAGTPEPAAVPSVPPPSGARFAGAGSGGGG
                     RRRKDAAEADRAAARRAAARRLAGETAAAVAALRDAGRTGEAYGRLSAAAAGPPEVLPD
                     LAAELERTAGTAEVATLLWEAAALPPEGLTGAADAFAAAGRAREALQLVRYAAARPVPE
                     LAAILSALHRAGRDRESEELLDAFAASRGTDEAVELAGADPGRLVPQLLRAARRGPAQR
                     HRRLALAMRSAGLPGAPESA"
     gene            2860..3702
                     /locus_tag="DMB38_RS30345"
                     /old_locus_tag="DMB38_30335"
     CDS             2860..3702
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578982.1"
                     /locus_tag="DMB38_RS30345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30335"
                     /product="nitrilase-related carbon-nitrogen hydrolase"
                     /protein_id="WP_125937825.1"
                     /transl_table=11
                     /translation="MANVVRAALVQATWTGDTESMIAKHEEHARAAAAGGARIIGFQEV
                     FNAPYFCQVQEPEHYRWAEPVPDGPTVVRMRALARETGMVVVVPVFEIEQEGFYYNTAV
                     VIDADGTVLGKYRKHHIPQVKGFWEKYYFKPGNAGWPVFDTAVGRVGVYICYDRHFPEG
                     WRALGLAGAQLVYNPSATSRGLSAYLWQLEQPAAAVANEYFIAAINRVGVEEYGDNDFY
                     GTSYFVDPRGQFVGDVASDKEEELVVRDLDFGMIEEVRRQWAFYRDRRPDAYGDLVQP"
     gene            3771..4997
                     /locus_tag="DMB38_RS30350"
                     /old_locus_tag="DMB38_30340"
     CDS             3771..4997
                     /NRPS_PKS="Domain: Aminotran_3 (10-347). E-value: 1.9e-71.
                     Score: 232.8. Matches aSDomain:
                     nrpspksdomains_DMB38_RS30350_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470645.1"
                     /locus_tag="DMB38_RS30350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30340"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_125939381.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-80, bitscore:
                     269.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALYYAEPIEITHGEGRHVWDAEGNRYLDFFGGILTTMTAHALPE
                     VTKAVAEQAGRILHTSTLYLNRPMVELAERIAQLSGIPDARVFFTTSGTEATDTALLLA
                     STYRGSNQVLAMRNSYHGRSFTAVGITGNRAWSPTSLSPLQTLYVHGGIRTAGPFADLD
                     DAAFIDACVADLRDMLSQTRGVAALIAEPVQGVGGFTSPPDGLYAAFREVLAEEGILWI
                     TDEVQSGWGRTGDHFWGWQAHAGNGPPDMLTFAKGIGNGTSIGGVVARAEIMNCLDANS
                     LSTFGGSPVTMAAGLANLGYVLEHDLQGNARRVGGLLIERLRAAAAGLASVREVRGRGL
                     MIGIELATPGHAAAVLEHARAGGLLVGRGKAGETLRIAPPLSLTVAEAEEGAAVLERAL
                     HAADAETGG"
     aSDomain        3801..4811
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMB38_RS30350_Aminotran_3.1"
                     /evalue="1.90E-71"
                     /label="DMB38_RS30350_Aminotran_3.1"
                     /locus_tag="DMB38_RS30350"
                     /protein_end="347"
                     /protein_start="10"
                     /score="232.8"
                     /tool="antismash"
                     /translation="ITHGEGRHVWDAEGNRYLDFFGGILTTMTAHALPEVTKAVAEQAG
                     RILHTSTLYLNRPMVELAERIAQLSGIPDARVFFTTSGTEATDTALLLASTYRGSNQVL
                     AMRNSYHGRSFTAVGITGNRAWSPTSLSPLQTLYVHGGIRTAGPFADLDDAAFIDACVA
                     DLRDMLSQTRGVAALIAEPVQGVGGFTSPPDGLYAAFREVLAEEGILWITDEVQSGWGR
                     TGDHFWGWQAHAGNGPPDMLTFAKGIGNGTSIGGVVARAEIMNCLDANSLSTFGGSPVT
                     MAAGLANLGYVLEHDLQGNARRVGGLLIERLRAAAAGLASVREVRGRGLMIGIELA"
     gene            5277..5843
                     /locus_tag="DMB38_RS30355"
                     /old_locus_tag="DMB38_30345"
     CDS             5277..5843
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020610459.1"
                     /locus_tag="DMB38_RS30355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30345"
                     /product="response regulator transcription factor"
                     /protein_id="WP_346429529.1"
                     /transl_table=11
                     /translation="MLLVHDTMLIRSALAALLGGEQDLDVLTAACRHERRQAGDWQAQV
                     CVVDGDGAWSGLPDTTAEKVVILTETGRPGLLRRASQADVRGFVSKDSAPERLIAGIRR
                     VATGERYVDEALVCDFLRAADMPLTRRELAVLAAAAEGAPVAEIASALHLAGGTVRNYL
                     AAAIRKTGARNRVDAIRIADSAGWL"
     gene            complement(5890..7743)
                     /locus_tag="DMB38_RS30360"
                     /old_locus_tag="DMB38_30350"
     CDS             complement(5890..7743)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852154.1"
                     /locus_tag="DMB38_RS30360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30350"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_125937826.1"
                     /transl_table=11
                     /translation="MRDRDAEQRPAGRGAAAPRTGPAGPAPGLRVLVPAGLRFLRRRRR
                     VVGAVAGWSAVEALQTFLLGHALARAVDRGFLADRPGVGLAWLAAAAVGVAVGAFGTLR
                     VYGAVARLTEDLRDTLVRRVVTGALERAAARARAEGPAAVSRLTHQVEIARDGFAGLVM
                     VTRSFVVTAAAALLGLLTLAPPLLLVVLPPLVAGLAVFGWSLRPLSRRQRDFLAADEAL
                     ADGLGSVVDGLRDVVACGGERRAEYAVRARVDAELAASTALARWGTMRDVAVGVGGRLP
                     VLALLLAAPWLLARGVTAGALVGALAYLTQALLPALQSLVFGLGGTGTRLTVVAGRLYA
                     AGPPRPAPGDGGDEGTRDGDGAGLPRPRTGAAPGAPPGTPRPLAPGAVLELRRVSFRYG
                     PRSGAVIRGLDLVVRDGEHLAVVGPSGIGKSTLASLAAGLVLPGDGEVRRSCRPVLLPQ
                     EAYVFGGSLRDNLAYLCPSPVRDAELHHSVHAVGAAPLVARLGGLDAPLRPAELSAGER
                     QLLALARAHLAPPRLALLDEATCHLDPAAEAVAERAFAQRPGGTLVVVAHRVASAARAD
                     RVLVLDGRSALAGTHEDLLERSPFYRELTGAPGLVPTPPGS"
     gene            complement(7791..9656)
                     /locus_tag="DMB38_RS30365"
                     /old_locus_tag="DMB38_30355"
     CDS             complement(7791..9656)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852153.1"
                     /locus_tag="DMB38_RS30365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30355"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_125937827.1"
                     /transl_table=11
                     /translation="MDGSRAVQGPPDGAGGRGADPPAGGPEETGDGTRRLLLRAGRHSA
                     AYTAALCLVTTAAAGAALALPAMLGVALDRLLADSPGAPRALALCAALTAATILLDAAE
                     TVLNGVTTARTTAWLRRRLLGAALAAEPHRAARWATGDLVTRATGNAAHAGAAPAAAAS
                     TLGSLLTPVGALVALAVIDPWLAVVLGVGTPVLVLLLRAFVRSAGDCVTRYQEAQAAIA
                     ARLAEALAGARTIAAAGTAGRERGRVLGPLPELRRHGHRMWQVQGRATAQAAVVVPLLQ
                     LAVVAVAGLRLGAGRLSVGELLAAGRYAMLAGGIGVLVGHVNTLVRSRAAAQRLTPVLG
                     LPPVPYGPDAAPADGGGRLELRGVTVRRGGRTVLRELHLTVPAGATVAVVGRSGAGKSL
                     LAAVAGRLADPDAGDVRLDGVPLPALARTELRAAVAYAFARPALLGGTVAEALAYADAR
                     TPVTAGRVAAAARAADADAFVRALPAGYATPAADAPLSGGELQRLGLARAFAREARLLI
                     MDDALSGLDAATELRIERALLAPPGADERPGGGGAGGGAQGGGAALRTGTGRSRLIVAH
                     RVATAARADLVAWLDGGRVRALRPHAELCADPAYRALWSQEPPDA"
     gene            complement(9862..9978)
                     /locus_tag="DMB38_RS30370"
                     /old_locus_tag="DMB38_30360"
     CDS             complement(9862..9978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837057.1"
                     /locus_tag="DMB38_RS30370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30360"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_018837057.1"
                     /transl_table=11
                     /translation="MALLDLQALEASEQTGGGDSSLSLLCGKHSSHSVLLCL"
     gene            complement(10001..12814)
                     /gene="lanKC"
                     /locus_tag="DMB38_RS30375"
                     /old_locus_tag="DMB38_30365"
     CDS             complement(10001..12814)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837058.1"
                     /locus_tag="DMB38_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30365"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_125937828.1"
                     /sec_met_domain="micKC (E-value: 5.5e-223, bitscore: 741.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1e-05, bitscore: 23.2,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEAFCLADEYFYETPDRLAGGAGASVALFSVARRDTPEGWV
                     DAWSGDWRQLQPLADRDWPEQGWKVHVSARLDNADRIGTRIWDYCVPRAIPFKFVPGKQ
                     LLYLRNSKYASRTISGKFATIYPRDDAMLHTLLRELGEQLSAEDGPYILTDLRWRGGPL
                     HVRYGGFAPRYCVGADGALVPAVEGPDGTLVPDRKDPAFSVPDWVTLPGFLAPELAARN
                     ATTTSDLPYRIERALHFSNGGGVYAGTDLRDGTQVVLKEARPHAGLAADGADAVARLER
                     ERAALERLAGLGVAPGVRDWFELGGHRFLVMDFLPGRTLNSFFAERHPLLAADPDPAEV
                     ASYTRWAVRVHGAVERAVAAVHGRGLVFNDLHMFNIMVAPEADAAAGGADAGGADAAEP
                     SVALVDFEAAAPVADGPRQIVAHPGYVAPADREGFAIDRYALACLRIALFLPMTTLLAV
                     DRRKAAHLARVAAEEFPELPEEFLREAVEEITGDTGAGARTAGAVPGAVAAGGTGGPPA
                     SPSAPVAARPGAAAGGEPLLPVEPGDWPRSRAAMARALAASATPERDDRVFPGDVAQFN
                     DGGGLGISFGAAGVLYALAEAGAPRNEAGEEWLLKRTAAPPRGTPFGLYDGLLGVAYVL
                     ERLGHGKRALDLVEQVLAENWQALASPLHGGLAGAGLVLDHLATACGEPSLHDHALRAA
                     TLLTGRLAAAGPAYDGGAARTPAARGGERAGLLRGWTGPALFFLRLYERTGDPALLDAA
                     ATALRRDLARCRTDRTGGLVVDEGHRTMPYLGDGSAGIAAVLDDYLAHRGDEDFAAARA
                     AVLPAVRMRYYAQPGLFQGRAGMLLHLGRTATPGVRAADPAAQAAALSWYALPYGGGLA
                     FPGDQMMRLSMDLATGTAGCLLALAAAQPGSDAGLPFLPPAHRRGRRADRPHDGAGVPA
                     PSGKSRQ"
     misc_feature    13039..13054
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.08"
                     /tool="antismash"
     misc_feature    13043..13058
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            13093..14493
                     /gene="hydA"
                     /locus_tag="DMB38_RS30380"
                     /old_locus_tag="DMB38_30370"
     CDS             13093..14493
                     /EC_number="3.5.2.2"
                     /GO_function="GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hydA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491454.1"
                     /locus_tag="DMB38_RS30380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30370"
                     /product="dihydropyrimidinase"
                     /protein_id="WP_125937829.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 9.9e-24, bitscore:
                     82.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRTVITGGLVITAADEIHADVLVEDGRVTALAAHGSDAAAGWRE
                     GAAVIDATGKYVIPGGVDAHTHMELPFGGTFASDTFETGTGAAAWGGTTTIVDFAVQKQ
                     GSALREGLDAWHAKADAQCSIDYAFHMILSDVNEHTLKEMDRLVEEGVTSFKLFMAYPG
                     VFYSDDGQILRAMQRAAGNGGLIMMHAENGIAIDVLVEQALKAGKTDPRYHGEVRKVLL
                     EAEATHRAIQLARVAGSPLYVVHVSAEEAVAELAQARDAGLPVFGETCPQYLFLSTDNL
                     AEPDFGGAKYVCSTPLRPKEHQSALWRGLRTNDLQVVSTDHCPFCFTGQKDLGRGDFSK
                     IPNGMPGVENRMDLLHQAVVDGHISRRRWIEIACAAPARMFGLYGRKGTIAPGADADLV
                     VYDPAAEQTISAETHHMNVDYSAYEGKRVTGQVETVLSRGELVIDRRTFVGRAGHGAYL
                     ARGLTQYA"
     gene            complement(14561..18136)
                     /locus_tag="DMB38_RS30385"
                     /old_locus_tag="DMB38_30375"
     CDS             complement(14561..18136)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533302.1"
                     /locus_tag="DMB38_RS30385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30375"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_240662550.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 7.1e-38, bitscore:
                     129.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRSWIRRGLTVLLAALPLTLSALPAQARPADPVPSSPYRAKAE
                     SKLIGQLAARSTGHDRGKVAFWVVLKDSADLGDVGKAEGRTAKARELRAVKTEFAEKSQ
                     APLIDLIEDAGAAHTSFWISNQIKVTGTKALAEKLAARSDVAALEADDPVKIPDPLPGT
                     GEPKTDAVEWNVDRINAPRVWNELGGRGEDVVIANIDTGVQYDHPALKSQYRGLKPDGT
                     YDHDYNWFDPAKVCTGNAPCDNNGHGTHTMGTMAGDDKGANQVGVAPGARWIAAKGCES
                     GSCSRGSLLASGQWIVAPTDQTGANPRPDLAPDVVNNSWGANVIDTWYKDTVQSWRAAG
                     IFPAFSNGNAGPSCNTSGSPGAYDNSYSSGAFDINNTIASFSSRGTGENGIIKPNLAAP
                     GVNIRSAWAGGGYNAISGTSMASPHTAATVALMWSAAPAIRGDIAATEEILDETAVDVD
                     NTTCGGTAARNNVFGEGRLDAFAAVNATPRGALGALRGTVTSGGSPLADATVTLDGPMK
                     ATRTTAADGTYTLPKGMVGDYRITVSKYGYLPATTTATIVENETVTKDVSVDEAPTAVL
                     KGVVSTETGAEAGASIVVQGTPARTTSAADGSYELTLPVGTYDLAVTPASRCAAVSSIG
                     VELTADTTKNLELASRADTFGTTCRLVGGGFPTGDTKLTVSSNTTGTAPVALPFPVSFY
                     GKTYRNLTANTEGSLYFGPSSTSSLNGTLPTTSTPNGALYPFWDNLQLDADSGIYTSTQ
                     GTAPHRTVTVEWRDVVITSGSTQRISFSVVAGEDGSFSYHYKDIGTGSYENGSSATIGV
                     ENPTGTDALLYSFNQGVVSDGLAIGFRTSKSGLLSGTVTDANDNKAVADATVTVAKDGS
                     EVATGTSSTDGTYLVSVPAGTDATDYDITITGTHYSTATAGRSVKAAGIEVADATLTTA
                     LVTAASPAYELVVPAGQSRTRTLEIANSGTATGYTVAEKDGADWVTPSTASGTLEAGDS
                     EKLGLTFDTTGATPGSVLTGTLLLDSESGRRPVIEIPLKVVVPAYQAALDSGASAKAVD
                     ALGDTWGPDQEYTSGSFGYLGTTSKASTKQTIAGTNEQALYSTAREGAYEYRFDGLPDG
                     VYEVDLGFAELGPKDPARRVFDVMAEGGVKVDNLDIALEAGIYTAEDRTVTVTVTDGQL
                     NLRLVAGTGKTLINKIRVSHRPDLS"
     misc_feature    18421..18436
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.35"
                     /tool="antismash"
     gene            18734..19753
                     /locus_tag="DMB38_RS30390"
                     /old_locus_tag="DMB38_30380"
     CDS             18734..19753
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847702.1"
                     /locus_tag="DMB38_RS30390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30380"
                     /product="TIGR03842 family LLM class F420-dependent
                     oxidoreductase"
                     /protein_id="WP_125937831.1"
                     /transl_table=11
                     /translation="MDFGLVLQTDPPASAVVGLMRRAENNGFRYGWTFDSTVLWQEPYV
                     IYSRILEHTDRLTVGPMVTNPGTRTWEVTASAFATLNEMYGNRTVCGIGRGDSAMRVAG
                     RPPNTLARLGDAIRVIRDLAEGREAVVDRESGTTLRLPWVENGRLPVWMAAYGPKALAL
                     AGQVADGFILQLSDVYLTEFMVKAVRTAAAQAGRDPDDLTICVAAPAYVTDGTPEALAH
                     AREQCRWFGGMVGNHVADLVDRYGEHSDVVPEALTAYVKQRQGYDYSHHGRAGNPSTDF
                     VPDDIVDRFCVLGPVEAHLEKLRRLRELGVHQFAIYAMHDAKESTIDAYGKYVIPALA"
     gene            19763..21319
                     /locus_tag="DMB38_RS30395"
                     /old_locus_tag="DMB38_30385"
     CDS             19763..21319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837061.1"
                     /locus_tag="DMB38_RS30395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30385"
                     /product="NCS1 family nucleobase:cation symporter-1"
                     /protein_id="WP_125937832.1"
                     /transl_table=11
                     /translation="MTADAASPSYPQPPADGLAAPADDLAGSRYANADLLPVPAEQRTW
                     TTYNFAALWVGMAVNVPTWTLAAGLIALGMDWKQAVLTIALANVIVLLPMLLTGHAGPK
                     YGIPFPVLARSSFGVVGANLPALLRGVVACAWFGIQTWIGGQAIYFLAGKIIGAGSWWV
                     EAGSWGGYPWPQWLCFVLFWFIEIGIILFGMEGVKKLENWAAPLMLAGAAALLIWIADQ
                     AGGFGPLLDEPSELGWGTEFWKVFFPALMGMIGFWSTLSLNIPDFTRFGAGQRAQIWGQ
                     SLGLPTTMAAFALLSVLVTSGSQAVYGKPIWEPAELAARMDTKLGIAFALFVILLATLT
                     TNVAANLVSPAYDLSNLAPKAISFRTGSLIACAAGMLMFPWELIANPDIYIFVWLGTYG
                     GLLGAVAGVLIADYWLVRRTVLALPDLYRRDGAYWYRGGWNWRGLLAFAVGALLAVGGS
                     HTDAGASGPYPEDGLIPFLKPLADYGWAVGLGASLVLYTLLMARTREKPVAAPPATAAP
                     R"
     gene            complement(21330..22691)
                     /locus_tag="DMB38_RS30400"
                     /old_locus_tag="DMB38_30390"
     CDS             complement(21330..22691)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013938.4"
                     /locus_tag="DMB38_RS30400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_30390"
                     /product="hypothetical protein"
                     /protein_id="WP_125937833.1"
                     /transl_table=11
                     /translation="MTSLTHPRLSGLGRNPAAPQDVLVRLAAHSAGRHGIRLRRGMLAD
                     AVVEALLTYGDENSAVGLHGDRVSPAMRRRIAEHPDPAIRDAYVNFVRDMVDRGVALGI
                     DDLEEAYGRPRTALAGAPDARLRAVVAEAWHDRPLAVQVRLLADPDPAVRAAATLRERP
                     GVPPEWRDRCLADPAVRVNAARHVPLTPDWFARLMRSGDEEVFAAVAKNPHLSAEMVAQ
                     LLEVDDLHVRVAVTRSRHVDEETRARIYALVEAKDLKGSIEVRMMLDWGLADPDWLREA
                     PVGERMRYLESPHTPFRRVLASCRDLPAEAWQRLDNDPDLSVRRAAARRPDTPPEVLER
                     LVRTDGDPFHLRPLHVDHPNYPRRTLRSLADEENPHVRCVALQDPELPVAPLRRLASAD
                     ESFLRRGVAAHPNVPDVLLAQLLSDPEAGVAEEAAANPVLRVSRMSRILAAAGL"
     misc_feature    complement(21630..21632)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ggtggagacc gcctcccagg tcagcgtcac cccctcgggc agcagccggg cggcgaaggg
       61 ggagtcgacc gcgcccgtgc tgcgcagcag gctgcccacg ggggtgcggt cggcgacgaa
      121 cacgccgcgg ccgaactgcc cgtgggcgta gccggcggcc ttcagcaccc gcacggcccg
      181 gtcgacggtc tggtcgctcg ccgcgtacgc gcgcttgagc tgggagcgcg acgggatctg
      241 cgcccccacg gacagctcac cgccgtcgat ccgctcgcgc agatcgtcgg cgatgcgctg
      301 gtacaccggc ttggcgtcgc ccatacccgg gggctcctct cccgcaactc gcccgacagg
      361 ctaggtactc agggagcgaa tgcgtaccta ggtcggcttc cttgccacgt tggccgccgg
      421 gcgtgcgctc cggccgcgcg ggcgcgccgt ggcggggtca cgacttgccg tgcttcccgt
      481 tcggctgggc gagcggcgtc tgtgcctgct tggtcacgtc gccgacgagt tccaccacat
      541 cgggtccgta cgactgcgag ttgacgacct tcaggagcag gacgaaggag ttgctgccgt
      601 acttccggtt cagccggctc tcgttcttca ccagatagcg catcgccgcc tggttggtga
      661 tggagcgctg gccgcacgag aggaagaccg gcctggcctc ctggcccgcg gagagccggg
      721 ccagcagcac gtgctcgctc accccgttct ccagccggta gcgctccgtg cccaccgcga
      781 acgcaccgcg gtcggggccc ggctcggggt cggtgttgat ccgtaccccc ggcagcaggg
      841 actgcatgtg cgcggccatg cggcggttgg atatcggggt gccgacgcag aactcggtgc
      901 ggtcgccgaa cgtctgctgc gcggtgtcct gcgcgacgac ctgcgcgtgc gccccgcagg
      961 acttgatcac cgcggacagc tccagcaggg cgagcgcgtc gtgcttggcc acgctccagt
     1021 ccccgccgcc ggcgtcccgg ttcaccacga ccagggcctc cgagttccgc ggcagcccga
     1081 agaagcgctc ccggcgccgg tggcggcgcc cgacgaggct gccgcgcgcg taccacccga
     1141 gcgcggcgcc gaccacgagg ccggcggcgg ccgagacgag gacgaggatg ggttcgctca
     1201 tgaccgggca tgctagcggt cgtccgtaac attgttcgag gctgccgtac ctcgggttcc
     1261 gtttaccgcg gctgcaaagc ccccgtagcg cggacgaaat acaacgggtg tcgaatgccc
     1321 gccgtggcgg aacaatcgct gccgccggaa atggcggaat tcgcgcgatt cttgcggcag
     1381 atcacaggat ggctggatga agggtccggc tggtacggag tctttcgccg cggcgatccc
     1441 gacgggctgc aagcctgcct ggacggctcc gtgccggccc cgtgggacgt cgtcgagtcg
     1501 ctcctgcacg acctggccga gcacgccgga cggcgtacgg cggacgcggc gctgccgcgc
     1561 gcccgcgatc tgcaccgcgc cgccgtcgcc gcccacgacg cccgcagccc cgaccccgcc
     1621 gccctgaccg cggtgctccg cgcccggctc gcggagcacc gcacggcgga ggaggacgtc
     1681 gagcggctgc gcgaccggct ggcggtggag cgcaacccct ggacggcgga gcaactggag
     1741 tacgagctgg cgtgggtgcg cgacgacgcc gcccgcgcgg ccgcccgctg tgcggaactg
     1801 cgcggccgga tcgaggcgct ggcgcggcag gcggcgggcc gggagcccgc gcccccgccc
     1861 ccggcggcac tccggggcgc ccggttcgcg ggagccgcct cggcgccgcc gccggtgctg
     1921 cccgccgtgg gcggcgcgta cgagggcgtg ccgccggacg ccgccgaggc cggcgccgcc
     1981 gagccgcccc cgccccgggg cgcccggttc ccgggccccg gtaccgaggg ggccggcggt
     2041 ccgcccgcgg ccgggacccc ggagccggcc gccgtgccgt ccgtaccgcc gcccagcggc
     2101 gcccggttcg ccggcgccgg gtccgggggc ggcgggcggc gccggaagga cgccgcggag
     2161 gccgaccgcg ccgccgcccg gcgcgccgcc gcgcgccggc tcgccggcga gaccgccgcc
     2221 gccgtggccg ccctgcgcga cgcgggccgt accggcgagg cgtacggccg gctcagcgcc
     2281 gccgcggcgg gcccgccgga ggtgctgccc gacctcgccg ccgagctgga gcgcaccgcc
     2341 ggcaccgccg aggtggcgac cctgctgtgg gaggccgccg cgctgccccc cgaggggctg
     2401 accggggccg cggacgcgtt cgccgcggcc ggccgtgcgc gcgaggcgct gcagctcgtc
     2461 cggtacgccg ccgcccggcc cgtacccgag ctggccgcga tcctctccgc cctccaccgc
     2521 gcgggccgcg accgggagtc ggaggaactg ctcgacgcct tcgccgcctc ccgcggcacc
     2581 gacgaggccg tcgagctggc cggggccgat cccggccggc tcgtgccgca gttgctgcgc
     2641 gccgcccgcc gcgggcccgc ccagcgccac cgccggctcg cccttgcgat gcgctccgcg
     2701 ggcctgccgg gtgcgcccga atccgcctga accgggccgt tccgcccggc cggcgttcgg
     2761 tgcgccgctc ttgccagcgc caccgcggcg acttacgttc agagatccgc ccggcctcta
     2821 cgtgcgtaga gcctccggcg tcccgtccga ggagcagcca tggccaacgt tgtacgcgcc
     2881 gcactcgtcc aggcgacgtg gaccggcgac accgagtcga tgatcgcgaa gcacgaggag
     2941 cacgcgagag ccgccgccgc cggcggcgcc cgcatcatcg gcttccagga ggtcttcaac
     3001 gccccttatt tctgccaggt gcaggagccc gagcactacc gctgggccga gcccgtaccc
     3061 gacgggccca ccgtcgtacg gatgcgggcg ctcgcccgcg agaccggcat ggtcgtggtc
     3121 gtcccggtct tcgagatcga gcaggagggc ttctactaca acaccgcggt cgtcatcgac
     3181 gccgacggca cggtcctcgg taaataccgc aagcaccaca tcccgcaggt caagggcttc
     3241 tgggagaagt actacttcaa gccgggcaac gccgggtggc cggtcttcga caccgccgtc
     3301 ggcagggtcg gcgtctacat ctgctacgac cggcacttcc ccgagggctg gcgcgccctc
     3361 ggcctcgccg gcgcccagct cgtctacaac ccgtcggcga cctcgcgcgg cctgtcggcg
     3421 tacctgtggc aactggagca gcccgcggcg gccgtcgcca acgagtactt catcgccgcc
     3481 atcaaccgcg tcggcgtcga ggagtacggc gacaacgact tctacggcac gagctacttc
     3541 gtcgaccccc gcggccagtt cgtcggcgac gtcgcgagcg acaaggagga ggaactggtg
     3601 gtgcgcgacc tggacttcgg catgatcgag gaggtccgcc ggcagtgggc cttctaccgg
     3661 gaccgccgcc cggacgccta cggggacctg gtgcagccgt gagcgcggcg aacggcggcg
     3721 gcgtacaccg cgatctgctc gcccggcacc gggccgtcct gcccgactgg atggcgctct
     3781 actacgccga gcccatcgag atcacccacg gcgagggccg gcacgtctgg gacgccgagg
     3841 gcaaccgcta cctcgacttc ttcggcggca tcctcaccac catgaccgcc cacgccctcc
     3901 cggaggtcac caaggcggtc gccgagcagg ccggccgcat cctgcacacc tccaccctct
     3961 acctcaaccg ccccatggtg gagctggccg agcgcatcgc gcagttgtcc ggcatccccg
     4021 acgcgcgggt gttcttcacc acctcgggca ccgaggccac cgacacggcg ctgctgctgg
     4081 cgagcacgta ccgcggctcc aaccaggtgc tggccatgcg caacagctac cacggccgct
     4141 ccttcaccgc ggtcggcatc accggcaacc gcgcctggtc gcccaccagc ctctccccgc
     4201 tgcagaccct ctacgtccac ggcggcatcc gcaccgcggg ccccttcgcc gacctcgacg
     4261 acgccgcgtt catcgacgcc tgtgtcgccg acctgcgcga catgctctcc cagacccgcg
     4321 gcgtcgccgc cctcatcgcc gaacccgtcc agggcgtcgg cggcttcacc tccccgcccg
     4381 acggtctgta cgcggcgttc cgcgaagtgc tcgccgagga ggggatcctg tggatcaccg
     4441 acgaggtgca gtccggctgg ggccgtaccg gcgaccactt ctggggctgg caggcgcacg
     4501 cgggcaacgg cccgccggac atgctcacct tcgccaaggg gatcggcaac ggcacctcca
     4561 tcggcggcgt cgtcgcccgc gccgagatca tgaactgcct ggacgccaac tccctctcca
     4621 cgttcggcgg cagcccggtc accatggccg cgggcctggc caacctcggc tacgtcctgg
     4681 agcacgacct ccagggcaac gcccgccgcg tcggcggcct gctcatcgag cggctgcggg
     4741 ccgccgcggc gggcctcgcc tcggtgcgcg aggtacgcgg ccggggcctg atgatcggca
     4801 tcgagctggc cacccccggg cacgccgcgg cggtgctgga gcacgcccgc gcgggcggcc
     4861 tgctcgtcgg ccggggcaag gccggcgaga cgctgcgcat cgcgccgccg ctctccctca
     4921 ccgtcgcgga ggcggaggag ggcgcggccg tactcgaacg ggccctgcac gccgccgacg
     4981 cggaaaccgg cggctgacgc ggagttcgca cgcacgaggg ccggccgtgg cgcgggagcg
     5041 cgcggccggc cttcggcttg cgggccccgg ttcccgggtt tcacgggccg acggctgtca
     5101 agggcccgga ggggggcgcg cagtcggtcc gcccgccggg ttgtgcgccc ttctcgcacc
     5161 gtgatgtccg gaactacgcg cacaaaacgg cgccgactcc gtgtattcat aagcgacccg
     5221 accgtgaccc cgtcgggctc gtttccgggt gacgaggggg gcgctcagtg atccgcgtgc
     5281 tgctggtaca cgacacgatg ctcatcaggt cggcgctggc cgccctgctg ggaggagaac
     5341 aggatctcga cgtactcacg gcggcgtgcc gccacgagcg aagacaggcg ggggactggc
     5401 aggcgcaggt gtgcgtggtg gacggcgacg gcgcgtggtc cgggctgccg gacaccaccg
     5461 cggagaaggt ggtgatcctc accgagacgg gccggccggg gctgctgcgc cgggcctcgc
     5521 aggccgacgt gcggggcttc gtcagcaagg actcggcgcc ggagcggctg atcgccggca
     5581 tccggcgggt ggcgaccggc gagcggtacg tcgacgaggc cctggtctgc gacttcctca
     5641 gggcggcgga catgccgctc acccgcaggg aactggcggt gctcgcggcc gcggcggagg
     5701 gggcgccggt cgcggagatc gcgtcggccc tgcacctggc gggcggcacc gtccgcaact
     5761 acctcgccgc ggcgatccgc aagacgggcg cgcgcaaccg ggtcgacgcc atccgcatcg
     5821 cggacagcgc gggctggctc tgacagcctt cccgtccgcc cggggcagcg acacgggcgg
     5881 acgggaaggt cagcttccgg ggggcgtggg cacgagcccg ggggcgccgg tcagctcgcg
     5941 gtagaagggc gagcgttcca gcaggtcttc gtgcgtgccc gccagcgccg accggccgtc
     6001 caggaccagc acccggtccg cccgcgccgc cgacgccacg cggtgcgcga cgaccacgag
     6061 cgtccccccg ggccgctgcg cgaacgcccg ctccgcgacc gcctccgcgg ccgggtcgag
     6121 gtggcacgtc gcctcgtcga gcagcgcgag ccgcggcggc gccaggtgcg cgcgggcgag
     6181 cgcgaggagc tgccgctccc cggcggacag ctccgcgggc cgcagcggcg cgtccagccc
     6241 gccgagccgg gccacgaggg gcgccgcgcc gacggcgtgc acggagtggt ggagttccgc
     6301 gtcccgcacg ggggaggggc acagataggc gaggttgtcg cggaggctgc cgccgaacac
     6361 gtacgcctcc tgcggcagca gcaccgggcg gcaggaccgg cgcacctcgc cgtccccggg
     6421 cagcacgagc ccggccgcca gactcgccag cgtcgacttc ccgatgccgc tgggtcccac
     6481 gacggccagg tgctccccgt cccgtacgac gaggtcgagc ccgcggatga cggcgccgga
     6541 gcggggcccg taccggaagg agacccgccg cagttcgagc acggcgccgg gagcgagggg
     6601 gcggggggtg ccgggcgggg cgccgggtgc cgcgccggta cgggggcggg ggagcccggc
     6661 cccgtcgccg tcccgggtgc cctcgtcgcc gccgtccccg ggggccgggc gcggggggcc
     6721 cgcggcgtac agcctgcccg ccaccaccgt cagccgggtg cccgtgccgc cgaggccgaa
     6781 gaccagcgac tgcagcgccg ggagcagcgc ctgcgtgagg tacgccagcg cgcccaccag
     6841 cgcgcccgcc gtcaccccgc gggccagcag ccatggcgcg gccagcagca gggccagcac
     6901 cggcagcctg ccgccgacgc ccacggcgac gtcccgcatc gtgccccagc gcgccagcgc
     6961 cgtcgaggcg gccagctcgg cgtccacccg ggcccgtacg gcgtactccg cgcgccgctc
     7021 gccgccgcag gcgaccacgt cgcgcaggcc gtccacgacc gacccgagcc cgtcggccag
     7081 cgcctcgtcg gcggcgagga agtcccgctg gcggcgggag agcggacgca gcgaccagcc
     7141 gaagaccgcc agccccgcca ccagcggcgg cagcaccacg agcagcagcg gcggcgccag
     7201 cgtcagcagc cccagcagcg cggcggcggc ggtgacgacg aaggaccggg tcaccatcac
     7261 gagccccgcg aagccgtcgc gggcgatctc cacctggtgc gtcagccgcg acaccgccgc
     7321 cggcccctcc gcccgcgcgc gggccgcggc gcgctccagc gccccggtga cgacgcgccg
     7381 cacgagggtg tcccgcaggt cctcggtgag ccgggcgacg gccccgtaca cccgcagcgt
     7441 gccgaaggcg ccgaccgcga cgcccaccgc cgcggcggcg agccaggcga gccccacccc
     7501 ggggcggtcg gccaggaacc cccggtcgac ggcccgcgcg agggcgtgcc cgagcaggaa
     7561 ggtctggagc gcctcgacgg cggaccaccc ggccaccgcc ccgacgaccc gccgcctgcg
     7621 gcgcaggaac cgcagccctg cggggacgag gacccgcagc ccgggagcgg ggccggccgg
     7681 tccggtccgc ggggcggcgg cgccccggcc cgcggggcgc tgctcggcgt cgcggtcacg
     7741 catcggcggg ctcctcgtac tgccgcgcgc ggcacgcgcg ggcgccccgg tcacgcatcg
     7801 ggcggctcct gcgaccacag ggcgcggtac gcggggtcgg cgcacaactc cgcgtgcggg
     7861 cgcagcgcgc ggacccggcc gccgtcgagc cacgcgacga ggtcggcgcg cgccgcggtg
     7921 gccacccggt gcgccacgat cagccggctg cgccccgtgc cggtgcggag ggcggcgcca
     7981 cccccctggg caccgccccc cgcaccgccc ccgccgggcc gctcgtccgc cccgggcggc
     8041 gccagcagcg cccgctcgat gcggagctcc gtggccgcgt cgagcccgga gagcgcgtca
     8101 tccatgatca gcagccgggc ctcgcgggcg aacgcgcggg cgagacccag gcgttgcagc
     8161 tcgcccccgg acagcggcgc gtccgccgcg ggggtggcgt agccggcggg gagcgcgcgg
     8221 acgaaggcgt cggcgtcggc cgcccgcgcc gccgcggcca cgcggccggc cgtgaccggg
     8281 gtgcgggcgt cggcgtacgc gagggcctcc gcgaccgtgc cgccgagcag cgcggggcgc
     8341 gcgaaggcgt aggccaccgc cgcccgcagc tccgtgcgcg ccagcgcggg cagcggcacg
     8401 ccgtcgagcc gtacgtcgcc cgcgtccggg tcggcgagcc gtcccgccac cgcggcgagc
     8461 agcgacttgc cggcgcccga gcgccccacc accgcgaccg tcgcccccgc cggcaccgtc
     8521 aggtgcaact cgcgcagcac cgtccgcccg ccgcggcgca ccgtgacccc gcgcagctcc
     8581 agccggccgc cgccgtcggc gggtgcggcg tcgggcccgt acgggaccgg gggcagcccc
     8641 agcaccggcg tcagccgctg cgccgccgcc cggctgcgta cgagggtgtt gacgtgcccg
     8701 acgaggacgc cgataccgcc ggcgagcatc gcgtaccggc ccgccgccag cagctcgccc
     8761 acgctcagcc ggccggcgcc gagccgcagc ccggcgacgg ccacgacggc gagctggagc
     8821 agcggcacga cgacggccgc ctgcgcggtg gcgcggccct gcacctgcca catccggtgg
     8881 ccgtgccggc gcagctccgg caacgggccc agcacgcggc cccgttcgcg gccggcggtg
     8941 ccggcggcgg cgatggtccg cgccccggcc agggcctcgg ccagccgcgc cgcgatggcg
     9001 gcctgcgcct cctggtagcg cgtcacgcag tcgcccgcgc tgcggacgaa cgcgcgcagc
     9061 aggaggacga gtacgggggt gccgacgccg aggacgacgg cgagccaggg gtcgatgacc
     9121 gccagcgcga cgagcgcgcc gaccggggtg agcagagagc ccagggtgga ggcggcagcg
     9181 gcgggggcgg cgccggcgtg ggcggcgttg ccggtggcgc gggtgacgag gtcgccggtg
     9241 gcccagcggg cggcgcggtg cggctcggcg gccagcgcgg cgccgagcag gcggcggcgc
     9301 agccaggcgg tggtacgggc ggtggtgacg ccgttgagca cggtctcggc ggcgtcgagg
     9361 aggatggtcg cggcggtgag ggccgcgcac agggcgaggg cgcggggggc gccgggggag
     9421 tcggcgagca gccggtccag ggcgacgccg agcatcgcgg gcagggcgag cgccgcgccc
     9481 gcggcggcgg tggtgaccag gcagagcgcg gcggtgtacg cggcgctgtg ccgcccggcc
     9541 cgcagcagca gccgccgcgt cccgtccccg gtctcctccg gcccgccggc cggcggatcc
     9601 gctccccggc cgccggcgcc gtccggcggg ccctggaccg cccgggaacc gtccacgcaa
     9661 accgtccctt ccccgccgga ctccggtcgc cgcggcctcg tccgtacggc ccctgcgcgc
     9721 tccggtgtcc ccggcccctg cttctccgcc cgctgcttgc ccgtgccgcc tgccgccgtt
     9781 ccccgcccgc cgccccggcg aggggaccgc gcggccccgg gcgccgtcgt gtgcgcccgg
     9841 ggcctcttcg gtgcgggagg gtcacaggca gagcagcacg ctgtgcgagc tgtgcttgcc
     9901 gcacagcagg ctcaggctgc tgtcgccgcc gccggtctgc tcggaagcct cgagggcctg
     9961 aaggtcgaga agcgccatga tgtctccttg gttcactcgg ttactgccgg gacttgccgg
    10021 atggtgctgg tactccggcc ccgtcgtggg gccggtccgc ccgccgtccg cgccggtgcg
    10081 cgggcggcag gaagggcagg ccggcgtcgc tcccgggctg cgccgcggcg agcgcgagca
    10141 ggcagccggc ggtgccggtg gccaggtcca tggacagccg catcatctgg tcgccgggga
    10201 aggcgagccc gccgccgtac ggcagggcgt accaggagag cgcggcggcc tgggcggcgg
    10261 ggtccgcggc gcggacgccg ggggtcgcgg tgcggccgag gtgcagcagc atcccggccc
    10321 gcccctggaa caggccgggt tgggcgtagt agcgcatccg cacggcgggc aggaccgccg
    10381 cgcgcgccgc ggcgaagtcc tcgtcgccgc ggtgcgcgag gtagtcgtcg agcacggccg
    10441 cgatgcccgc gctgccgtcg ccgaggtacg gcatggtgcg gtggccctcg tcgacgacga
    10501 ggccgccggt gcggtcggtg cggcagcggg caaggtcgcg gcggagcgcg gtggcggcgg
    10561 cgtccagcag cgcggggtcg ccggtgcgct cgtacagccg gaggaagaag agcgcgggcc
    10621 cggtccagcc gcgcagcagc ccggcgcgct cgccgccgcg ggccgcgggg gtacgggccg
    10681 cgccgccgtc gtacgccggg cccgccgctg cgagccggcc ggtcagcagc gtggccgcgc
    10741 gcagggcgtg gtcgtggagg gacggctcgc cgcaggcggt cgcgaggtgg tcgagcacca
    10801 gcccggcgcc ggcgagcccg ccgtgcagag gggaggcgag cgcctgccag ttctcggcga
    10861 gcacctgctc gacgaggtcg agcgcccgct tgccgtgccc gagccgctcc agcacgtacg
    10921 ccaccccgag cagcccgtcg tacagcccga acggcgtacc gcggggcggc gcggcggtcc
    10981 gcttcagcag ccactcctca ccggcctcgt tccgcggcgc gccggcctcg gcgagcgcgt
    11041 acagcacgcc cgcggcgccg aacgagatcc cgaggccgcc gccgtcgttg aactgggcga
    11101 cgtcaccggg gaagacgcgg tcgtcgcgtt cgggggtcgc ggaggcggcc agcgcccggg
    11161 ccatggccgc gcggctgcgc ggccagtcgc cgggctcgac cggcagcagc ggctccccgc
    11221 ccgccgccgc gccgggtctc gccgccaccg gggccgacgg agaagcaggt gggccccccg
    11281 tgccgccggc ggcgacggcc ccgggcacgg cccccgccgt acgcgccccc gcccccgtat
    11341 ccccggtgat ctcctcgacc gcctcccgca ggaactcctc cggcagctcc gggaactcct
    11401 ccgccgccac ccgcgccaga tgcgcagcct tgcgccggtc gacggccagc agcgtcgtca
    11461 tcggcaggaa cagcgcgatc cgcaggcagg ccagcgcgta gcggtcgatc gcgaagccct
    11521 cgcggtccgc cggtgccacg taccccggat gcgcgacgat ctgccgcggc ccgtccgcca
    11581 ccggcgccgc cgcctcgaag tcgaccagtg ccaccgacgg ctcggccgcg tccgccccgc
    11641 ccgcgtccgc cccgcccgcc gcggcgtccg cctccggcgc gaccatgatg ttgaacatgt
    11701 gcaggtcgtt gaagacgaga ccgcgcccgt gcaccgccgc gacggcccgc tccaccgccc
    11761 cgtgcacccg caccgcccag cgggtgtacg acgccacctc cgccggatcc gggtccgcgg
    11821 ccagcagcgg gtggcgctcc gcgaagaagg agttgagggt acggcccggc aggaagtcca
    11881 tgaccaggaa gcggtgcccg cccagctcga accagtcgcg gacgcccggc gcgacgccga
    11941 gacctgccag ccgctccagc gcggcccgtt cccgctccag ccgggccacc gcgtcggcac
    12001 cgtcggcggc gaggccggcg tgcggccggg cctccttcag cacgacctgc gtaccgtcgc
    12061 gcaggtcggt gcccgcgtag acgccgccgc cgttggagaa gtgcagggcg cgctcgatgc
    12121 ggtacggcag gtccgaggtg gtcgtggcgt tgcgcgcggc cagctcgggc gccaggaagc
    12181 cgggcagcgt cacccagtcg ggcacgctga acgccgggtc cttgcggtcg gggacgagcg
    12241 tgccgtcggg cccctcgacg gccgggacca gcgccccgtc ggcgccgacg cagtagcgcg
    12301 gggcgaagcc cccgtagcgc acgtgcagcg ggccgccccg ccagcgcagg tccgtgagga
    12361 tgtacgggcc gtcctccgcg ctcagttgct cgccgagttc gcgcaggagc gtgtgcagca
    12421 tggcgtcgtc gcgcggatag atcgtggcga acttgccgct gatcgtgcgg ctcgcgtatt
    12481 tggagttccg gagatagagg agttgctttc ccggcacgaa tttgaacgga atggcccggg
    12541 gcacgcagta atcccagatg cgcgtgccga tccggtcggc gttgtcgagg cgggccgaga
    12601 cgtgcacctt ccagccctgc tccggccagt cgcgatcggc cagcggctgc aactggcgcc
    12661 agtctcccga ccaggcgtcg acccaccctt ccggggtgtc ccggcgggcg acggagaaga
    12721 gcgcgaccga ggcgccggcg ccgccggcca atcggtccgg agtttcgtag aaatactcgt
    12781 cggccaggca gaacgcctcg tatcgcttgt ccatttcccc ccagggccgt ctccttgact
    12841 gcgcccgtga aggatttcag ccgggcgggc gccggcagta gtcacggctg tcacgaagaa
    12901 ggcgtgcaga acgcacgggt acggcgtgcg gcgggcacgg ccggagcgtg cggcgcgcgc
    12961 cacgcggtgg cgacgggcgg ctgccgcggt attgccgagc gcggtgccat gcttctacgg
    13021 tcttcgcacg cagctcgact ctacgggtgt agacccctgg tgacgtcgcg tcgccggaag
    13081 ggagcagagg ccgtgagccg tacagtcatc accggcggtc ttgtcatcac cgccgccgac
    13141 gagatccacg ccgacgtgct cgtcgaggac ggccgcgtca ccgcactcgc cgcacacggc
    13201 agcgacgccg ccgccggctg gcgcgagggc gccgccgtga tcgacgccac cgggaagtac
    13261 gtcatcccgg gcggggtgga cgcccacacg cacatggaac tgcccttcgg cggcacgttc
    13321 gcctcggaca ccttcgagac gggcaccggc gccgccgcct ggggcggcac gacgaccatc
    13381 gtggacttcg ccgtacagaa gcagggcagc gcgctgcgcg aggggctgga cgcctggcac
    13441 gccaaggccg acgcccagtg cagcatcgac tacgccttcc acatgatcct ctccgacgtc
    13501 aacgagcaca cgctcaagga gatggaccgc ctggtcgagg agggcgtgac ctccttcaag
    13561 ctcttcatgg cctaccccgg cgtcttctac agcgacgacg gccagatcct gcgcgccatg
    13621 cagcgcgccg cgggcaacgg cgggctgatc atgatgcacg ccgagaacgg catcgccatc
    13681 gacgtcctcg tcgaacaggc cctcaaggcc gggaagaccg acccgcgtta ccacggcgag
    13741 gtgcgcaagg tgctgctgga ggccgaggcc acgcaccgcg ccatccagct cgcccgcgtc
    13801 gccggcagcc cgctgtacgt cgtgcacgtc tccgccgagg aggccgtcgc cgagctggcg
    13861 caggcccgcg acgccggcct gccggtcttc ggcgagacct gcccgcagta cctcttcctc
    13921 tccaccgaca acctcgccga gccggacttc gggggcgcga agtacgtgtg ctcgacgccg
    13981 ctgcggccga aggagcatca gtcggcgctc tggcggggcc tgcgcacgaa cgacctccag
    14041 gtcgtgtcga cggaccactg cccgttctgc ttcaccgggc agaaggacct cgggcgcggg
    14101 gacttctcga agatcccgaa cgggatgccg ggcgtggaga accggatgga cctgctgcac
    14161 caggcagtcg tcgacgggca catctcgcgg cgccgctgga tcgagatcgc gtgcgcggcg
    14221 ccggcccgga tgttcggcct gtacgggcgc aagggcacga tcgcaccggg cgcggatgcc
    14281 gatctcgtgg tgtacgaccc ggccgccgag cagacgatca gcgccgagac gcatcacatg
    14341 aacgtggact actcggcata tgagggcaag cgggtgaccg gacaggtcga gacggtcctg
    14401 tcgcgcggtg aactcgtcat cgaccggcgg acgttcgtgg gccgggccgg gcacggggcc
    14461 tatctggcac gggggctgac gcagtacgcg tagtccgccg ggcaccccgc ggcggtagcc
    14521 gggggagggc cgcgcagggc cctcccccgc cccgcgcggt ctagctgaga tccgggcggt
    14581 gcgagacgcg gatcttgttg atcagcgtct tgcccgtacc cgcgaccaga cgcaggttga
    14641 gctgcccgtc ggtgaccgtc accgtgacgg tgcggtcttc ggcggtgtag atgccggcct
    14701 ccagtgcgat gtccaggttg tcgaccttga cgccgccctc ggccatcacg tcgaagaccc
    14761 gcctcgccgg gtccttgggg cccagctcgg cgaagccgag gtcgacctcg tagaccccgt
    14821 cgggcaggcc gtcgaagcgg tactcgtacg cgccctcgcg ggcggtggag tacagggcct
    14881 gctcgttggt gcccgcgatg gtctgcttgg tggacgcctt cgacgtcgta ccgagatacc
    14941 cgaaggaacc ggacgtgtac tcctggtccg ggccccaggt gtcacccagc gcgtccacgg
    15001 ccttcgcgga cgcgccggag tcgagcgccg cctggtaggc gggcacgacg accttcaggg
    15061 ggatctcgat caccggcctg cggcccgact cggagtcgag cagtagcgtg ccggtgagca
    15121 ccgaaccagg ggtggcgccc gtcgtgtcga aggtgagccc gagcttctcg ctgtcgccgg
    15181 cttcgagagt gccggaggcg gtggacgggg tgacccagtc ggcgccgtcc ttctcggcca
    15241 ccgtatagcc cgtcgccgta ccggagttgg cgatctccag cgtgcgggtg cgggactgcc
    15301 cggcgggcac caccagctcg tacgccgggc tggctgcggt gaccagggcc gtcgtcagcg
    15361 tcgcgtcggc cacctcgatg ccggcggcct tcaccgagcg cccggctgtg gccgtcgagt
    15421 agtgcgtgcc ggtgatcgtg atgtcgtagt ccgtggcgtc ggtgcccgcc gggaccgaga
    15481 cgaggtaggt gccgtcggtg ctgctggttc cggtggcgac ctcgctgccg tccttggcga
    15541 ccgtgacggt ggcgtcggcg acggccttgt tgtcgttggc gtccgtgaca gtgccggaca
    15601 ggaggcccga cttgctggtg cggaaaccga tggcgaggcc gtcggagacg accccctggt
    15661 tgaaggagta gaggagggcg tcggtgccgg tcgggttctc gacgccgatg gtggcgctgg
    15721 aaccgttctc gtacgagccg gtgccgatgt ccttgtagtg gtacgagaac gagccgtcct
    15781 cgcccgcgac cacggagaag gagatgcgct gcgtggaccc cgacgtgatc accacgtcac
    15841 gccactcgac ggtcaccgtg cggtgcggtg cggtgccctg cgtcgacgtg tagatgccgg
    15901 agtcggcgtc gagctggagg ttgtcccaga aggggtagag ggcaccgttc ggcgtcgagg
    15961 tcgtcggcag ggtgccgttg agcgacgacg tcgaactcgg gccgaagtag agcgagccct
    16021 cggtgttggc cgtcaggttg cggtacgtct tgccgtagaa ggagacgggg aagggcagcg
    16081 cgaccggcgc cgtgcccgtc gtgttgctgg acacggtgag tttggtgtcg ccggtcggga
    16141 agccgccgcc gaccagccgg caggtcgtgc cgaacgtgtc tgctcgggag gccagttcga
    16201 ggttcttcgt ggtgtccgcg gtcagctcca ctccgatgct ggagacggcg gcgcagcggc
    16261 tggccggagt gacggccagg tcgtacgtgc cgacgggcag cgtcagctcg taactgccgt
    16321 cggccgccga ggtcgtcctg gcgggcgtgc cctggacgac gatcgaggcg cccgcctcgg
    16381 cgcccgtctc ggtcgagacg acgcccttga ggaccgccgt cggcgcctcg tcgacggaga
    16441 cgtccttggt gaccgtctcg ttctcgacga tggtcgcggt ggtcgtggcc ggcaggtagc
    16501 cgtacttcga cacggtgatc ctgtagtcac cgaccatgcc tttcggcagc gtgtacgtgc
    16561 cgtcggcggc cgtcgtacgg gtcgccttca tcggcccgtc gagggtgacg gtggcgtcgg
    16621 cgagcgggct gccgcccgag gtcaccgtgc cccgcagggc gccgagcgcg ccgcgcgggg
    16681 tggcgttgac cgccgcgaac gcatcgagac ggccctcacc gaacacgttg ttcctggctg
    16741 ccgtgccgcc gcacgtcgtg ttgtccacgt cgaccgcggt ctcgtcgagg atctcctccg
    16801 tcgccgcgat gtccccgcgg atcgcgggcg cggccgacca catcagggcc acggtcgccg
    16861 cggtgtgcgg cgaggccatc gacgtaccgg agatcgcgtt gtatccgccg cctgcccagg
    16921 cggaacggat gttgacaccc ggagcggcga ggttcggctt gatgatgccg ttctcgccgg
    16981 tgccgcgcga ggagaaggag gcgatggtgt tgttgatgtc gaaggcgccc gacgagtacg
    17041 agttgtcgta cgcgcccggg gaccccgacg tgttgcagga cgggccggcg ttgccgttgg
    17101 agaacgccgg gaagatgccc gccgcgcgcc aggactggac ggtgtccttg taccaggtgt
    17161 cgatcacgtt ggcgccccag gagttgttga ccacgtcggg ggcgagatcg ggacgtgggt
    17221 tggcacccgt ctggtccgtc ggggcgacga tccactggcc cgaggcgagc agtgacccgc
    17281 gggagcagga gccggactcg caccccttgg cggcgatcca ccgcgcgccg ggggcgacgc
    17341 cgacctggtt ggcgcccttg tcgtcgccgg ccatggtgcc catggtgtgg gtgccgtggc
    17401 cgttgttgtc gcagggggcg ttgccggtgc acaccttcgc cgggtcgaac cagttgtagt
    17461 cgtggtcgta cgtgccgtcc ggcttcagtc cccggtactg ggacttgagc gccgggtggt
    17521 cgtactggac gccggtgtcg atgttggcga tgacgacatc ctcgccgcgc ccgcccagct
    17581 cgttccagac ccggggagcg ttgatccggt cgacgttcca ctccacggcg tctgtcttcg
    17641 gctcgccggt gccgggcagc gggtcgggga tcttgaccgg gtcatccgct tccagcgcgg
    17701 ccacgtcgga gcgggcggcg agcttctcgg cgagggcctt ggtgcctgtc accttgatct
    17761 ggttggagat ccagaacgac gtgtgcgcgg caccggcatc ctcgatcagg tcgatcaacg
    17821 gggcctggga cttctcggcg aactcggtct tgacggcccg cagttcacgg gccttggccg
    17881 tccggccctc ggccttgcct acgtcaccga ggtcggcgga gtccttgagc acgacccaga
    17941 aggcgacttt gccccggtcg tgcccggtgc tccgggcggc gagctgtccg atcagcttgc
    18001 tctcggcctt cgcccggtag gggctcgacg gcacggggtc ggccggccgg gcctgtgcgg
    18061 gcagtgcgct cagcgtcagt ggtagtgcgg cgaggagaac ggtgagacct cgtcgtatcc
    18121 aacttcgtct agacacgaac tctccttggg tgagagcggg ttcgtaccga cgctcaagcc
    18181 gcccgtgctc cgtggtgcgg gcacaggtgg ggggccgcag tggcgggatg agacgcgaat
    18241 gatgatgcgg aagggcggcc ccggcccgac agggggcgat ttgcgccgcg gccggaccgc
    18301 cggggcgcgc cccggcccgc gaagcccact cacagccggc gtctccacct gggcgtacgt
    18361 cgccgggagc acgcccggac cgtccgtcgg ccaagggtga tatctcgcca gcacaagcga
    18421 ttgacgactt tacgacttgt cgtgaactcg acatctctgg ccggtggcgc tgccgatcgg
    18481 acggccgggc gcggcccccc ggcgcacccg cggcagcggc ggtcgcccgc cggtcccggc
    18541 gacgaaggct ggacgcgcgt agaacacctc ttgccaaccc ccgggaagaa gtccacgatg
    18601 gtgcctcccc gacgggcggg agttcaccgg ccacgcagga cacggccagt gacatcccgc
    18661 gcggcacctg ccagttcctg tagaaccagc caccagaccc acacctccgg catcgcgacc
    18721 caagggggcc gaagtggatt tcggactcgt gctgcagaca gatccgcccg catccgccgt
    18781 cgtcggcctc atgcgccgcg cggagaacaa cggcttccgc tacggctgga cgttcgactc
    18841 caccgtcctg tggcaggagc cgtacgtcat ctacagccgc atcctcgagc acaccgaccg
    18901 gctcaccgtc ggccccatgg tcaccaaccc gggcacccgt acctgggagg tcaccgcctc
    18961 cgccttcgcc accctcaacg agatgtacgg caaccgcacc gtctgcggca tcggccgcgg
    19021 cgactccgcc atgcgcgtcg ccggccgccc gcccaacacc ctggcccgcc tcggcgacgc
    19081 catccgcgtc atccgcgacc tcgccgaggg ccgcgaggcc gtcgtcgacc gcgagtccgg
    19141 cacgacgctg cggctgccgt gggtcgagaa cggccggctc ccggtgtgga tggcggcgta
    19201 cgggccgaag gcgctggcgc tcgccgggca ggtcgcggac ggcttcatcc tccagctctc
    19261 ggacgtctac ctcaccgagt tcatggtcaa ggccgtccgc accgccgccg cccaggcggg
    19321 ccgcgacccg gacgacctga cgatctgcgt cgccgccccc gcgtacgtca cggacggcac
    19381 ccccgaggcg ctggcgcacg cgcgcgagca gtgccgctgg ttcggcggca tggtcggcaa
    19441 ccacgtcgcc gacctcgtcg accgctacgg cgagcactcc gacgtcgtcc ccgaggcgct
    19501 cacggcgtac gtcaagcagc gccagggcta cgactactcc caccacggcc gcgccggtaa
    19561 cccctccacc gacttcgtcc cggacgacat cgtggaccgc ttctgcgtcc tcggccccgt
    19621 cgaggcgcac ctggagaagc tccgccggct gcgggagctg ggcgtgcacc agttcgcgat
    19681 ctacgcgatg cacgacgcga aggagtccac catcgacgcg tacgggaagt acgtcatccc
    19741 ggcgctggcc tgagggggcg ccatgaccgc ggacgccgcg tcaccgtcct acccgcagcc
    19801 gccggccgac ggcctggcgg cccccgccga cgacctcgcc ggcagccgct acgccaacgc
    19861 cgatctgctg cccgtccccg ccgagcagcg cacctggacc acgtacaact tcgccgcgct
    19921 gtgggtcggc atggcggtca acgtaccgac ctggacgctg gccgcgggcc tcatcgcgct
    19981 gggcatggac tggaagcagg cggtcctcac catcgccctg gcgaacgtca tcgtgctgct
    20041 gccgatgctg ctgaccggcc acgcgggccc caagtacggc atccccttcc cggtcctggc
    20101 ccgctcgtcg ttcggcgtcg tcggcgccaa cctgccggcg ctcctgcgcg gcgtcgtcgc
    20161 ctgcgcctgg ttcggcatcc agacgtggat cggcggccag gcgatctact tcctggccgg
    20221 gaagatcatc ggggccggga gctggtgggt cgaggccggc tcgtggggcg gctatccgtg
    20281 gccgcagtgg ctctgcttcg tgctcttctg gttcatcgag atcggcatca tcctcttcgg
    20341 catggagggg gtgaagaagc tggagaactg ggccgcgccg ctgatgctcg cgggcgcggc
    20401 cgcgctgctg atatggatag ccgaccaggc cggcggcttc ggcccgctgc tcgacgagcc
    20461 gtcggagctg ggctggggca ccgagttctg gaaagtgttc ttccccgcgc tcatgggcat
    20521 gatcggcttc tggtcgacgc tgtccctgaa catcccggac ttcacccgct tcggcgcggg
    20581 acagcgcgcg cagatctggg gccagtcgct cggactgccc accacgatgg ccgcgttcgc
    20641 gctgctgtcc gtgctggtca cgtcgggctc gcaggcggtc tacggcaagc cgatctggga
    20701 gccggcggag ctggccgccc ggatggacac caaactgggc atcgccttcg ccctgttcgt
    20761 catcctcctc gccaccctga cgacgaacgt cgcggccaac ctggtcagtc cggcgtacga
    20821 cctgtccaac ctggcgccga aggcgatcag cttccgcacc ggctcgctga tcgcgtgcgc
    20881 ggcgggcatg ctgatgttcc cctgggagct gatcgccaac ccggacatct acatcttcgt
    20941 ctggctcggc acctacggcg gcctcctggg cgcggtcgcc ggcgtcctga tcgccgacta
    21001 ctggctggtc cgccgcaccg tcctcgccct cccggacctg taccgccgcg acggcgcgta
    21061 ctggtacagg ggcggctgga actggcgcgg cctcctggcc ttcgcggtcg gcgccctcct
    21121 ggcggtaggc ggctcccaca ccgacgcggg cgcctcgggc ccgtacccgg aggacggcct
    21181 gatccccttc ctgaaacccc tggcggacta cggctgggcg gtgggcctgg gcgcgtcgct
    21241 ggtcctctac accctgctga tggcgcgcac ccgcgaaaag ccggtcgccg caccaccggc
    21301 gacagccgcc ccgcgctgac cctccacgct cacagaccgg cagccgcgag aatccggctc
    21361 atccgggaca cccggagcac gggattggca gcggcttcct cggcgacccc ggcttccggg
    21421 tcggagagca gttgcgccag cagcacgtct gggacgttgg ggtgagcggc gacaccacgg
    21481 cgcaggaagg actcgtcggc cgaggcgagt cgtcgaaggg gtgccacggg caactcgggg
    21541 tcctgcaagg ccacgcaacg gacgtgcggg ttctcttcgt cggcgagcga ccgcagtgtg
    21601 cgacgggggt agttggggtg gtcgacgtgt aacggccgga ggtggaaggg gtcaccgtcg
    21661 gtgcggacga gccgttccag cacctccggc ggtgtatccg gtcgccgggc ggcagcgcga
    21721 cggaccgaga ggtccgggtc gttgtccagc cgctgccatg cctcggcggg gaggtcacgg
    21781 caggacgcca ggacgcgccg gaacggggtg tgcgggcttt ccaggtagcg catccgttcg
    21841 ccgacgggtg cttcccgcag ccagtccggg tcggcgaggc cccagtccag catcatgcgg
    21901 acctcgatgc ttcccttcag gtccttggct tccacgagcg cgtagatccg ggcccgggtt
    21961 tcctcgtcga cgtgacggct ccgggtcacc gcgacccgca cgtgcaggtc gtcgacctcc
    22021 aggagttgcg caaccatctc cgccgagaga tgcgggttct tggcgacagc cgcgaagacc
    22081 tcctcgtccc cgctccgcat gagccgcgcg aaccagtccg gcgtgagcgg gacgtggcgc
    22141 gccgcgttga cgcgcacggc ggggtcggcg aggcagcggt cccgccattc cggcggtacg
    22201 cccggccgct cccgcagggt ggcggcggcg cggaccgccg gatccgggtc ggcgagcagc
    22261 ctcacctgta cggcgagcgg ccggtcgtgc cacgcctccg ccaccacggc gcgtagcctt
    22321 gcgtccggcg cgccggcaag tgcggtccgc ggcctgccgt aagcctcttc gagatcgtcg
    22381 atgccgagcg ccaccccgcg atccaccatg tcgcggacga agttcacgta cgcatcccgg
    22441 atcgccggat cgggatgctc cgcaatcctc cggcgcatcg ccggagagac ccggtccccg
    22501 tgcaggccca cggcgctgtt ctcgtcgccg tacgtcagca gtgcttcgac gacggcgtcc
    22561 gccagcattc cgcggcgcag tcttatcccg tgccggcccg ccgagtgtgc ggccaggcgc
    22621 accagaacgt cctgcggggc cgccggattc cggcccagtc cggacagccg cggatgcgtg
    22681 aggctcgtca tgcgctcaac ctagccaagc cgccccgtgg cggcccgccc tcggccgaac
    22741 cgggcgggcc cctacgcgct ctccgccgtc agccgcgcca gcaggggtgg cagggcctcg
    22801 ctgatcggct cgcg
//
