LOCUS       NZ_CP029618            22205 bp    DNA     linear   CON 19-MAY-2024
DEFINITION  Streptomyces sp. WAC 06738 chromosome, complete genome.
ACCESSION   NZ_CP029618
VERSION     NZ_CP029618.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. WAC 06738
  ORGANISM  Streptomyces sp. WAC 06738
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8324535)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Evolution of GPA BGCs
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8324535)
  AUTHORS   Waglechner,N. and Wright,G.D.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-MAY-2018) Michael G DeGroote Institute for Infectious
            Disease Research, McMaster University, 1280 Main St West, Hamilton,
            Ontario L8S 4L8, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. Jun-2017
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 148.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003945505.1-RS_2024_05_19
            Annotation Date                   :: 05/19/2024 05:01:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,191
            CDSs (total)                      :: 7,115
            Genes (coding)                    :: 6,917
            CDSs (with protein)               :: 6,917
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 58
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 198
            CDSs (without protein)            :: 198
            Pseudo Genes (ambiguous residues) :: 0 of 198
            Pseudo Genes (frameshifted)       :: 107 of 198
            Pseudo Genes (incomplete)         :: 115 of 198
            Pseudo Genes (internal stop)      :: 5 of 198
            Pseudo Genes (multiple problems)  :: 27 of 198
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 06:28:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1850378
            Orig. end                         :: 1872583
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP029618.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Gerard D Wright, McMaster
            University, 1280 Main St West, Hamilton ON, Canada.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22205
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="indole"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..22205
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="indole"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20990
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20990
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10990](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10990)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(358..543)
                     /locus_tag="DMB38_RS07745"
                     /old_locus_tag="DMB38_07755"
     CDS             complement(358..543)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMB38_07755"
                     /product="hypothetical protein"
                     /protein_id="WP_125934529.1"
                     /transl_table=11
                     /translation="MAATAAPALADGIPFAKTAACTTQAVVGSGARATLTSCTDDGTIR
                     VTGQLQSTWTTANARA"
     gene            complement(696..1121)
                     /locus_tag="DMB38_RS07750"
     CDS             complement(696..1121)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_125934530.1"
                     /transl_table=11
                     /translation="MATVQRRAAGFGAGLVAAAALLTSGAANAADSDEMTVKALCSDYQ
                     TQQDLDPTPNGSYAKWDTGQHTGPAYTCGRVRVVDSNDGLDYHCATDSRDSNGYRWTHV
                     RFTAADPDLKSSYGWIRNDKLTNGGSSESCLNQPTFP"
     cand_cluster    1072..22205
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1072..22205
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[11071:12205](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(11072..12205)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="2"
     gene            complement(1588..1923)
                     /locus_tag="DMB38_RS07755"
                     /old_locus_tag="DMB38_07765"
     CDS             complement(1588..1923)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154080.1"
                     /locus_tag="DMB38_RS07755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07765"
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="WP_125934531.1"
                     /transl_table=11
                     /translation="MIIFGTRSTAVQLAVINLLCGMCGNPAAHSLLKRVTKFTLFFIPL
                     FPVSTKYFTQCTFCGASGQITKEQSEQFQLQAAPQSSPQQDTGNPFAQEPAPQQQPQTG
                     GRNPYSS"
     misc_feature    complement(1909..1924)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.1"
                     /tool="antismash"
     misc_feature    1912..1927
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.9"
                     /tool="antismash"
     misc_feature    complement(2016..2034)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.99"
                     /tool="antismash"
     misc_feature    2019..2037
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.72"
                     /tool="antismash"
     misc_feature    2148..2161
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(2206..2580)
                     /locus_tag="DMB38_RS07760"
     CDS             complement(2206..2580)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_125934532.1"
                     /transl_table=11
                     /translation="MKALAQRVVEPAAVSIAAAAIALGTVGPASADSPTIPYGGCDVMW
                     ISSPRMFLIWDTDVNGKQCAVQYSYKADHTPNKWIYHPKDMSGYDSYPVSNPDGDKWVF
                     FRVCEAVSAFSCTSWKQYAT"
     gene            complement(2894..3388)
                     /locus_tag="DMB38_RS36425"
     CDS             complement(2894..3388)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013936.4"
                     /locus_tag="DMB38_RS36425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_125934533.1"
                     /transl_table=11
                     /translation="MTSNFKHQLLLHHTVEDDVLWPRPTDKVAHPPDYRLLLADMEAEH
                     ARIDQLLASVEAALEEPAADLVEQVDRRRKSLVERLDHEEKSALPLIQEVLTPADWRVF
                     ASRMRERQGIRGAAVYVPWITDSMPAADRERFLAHLPPPVRVVNRRLWEPRYGKSGMSA
                     V"
     gene            complement(<3380..>3639)
                     /locus_tag="DMB38_RS36040"
                     /old_locus_tag="DMB38_07775"
                     /pseudo=""
     CDS             complement(<3380..3639)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377440.1"
                     /locus_tag="DMB38_RS36040"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="DMB38_07775"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLPGRTHDLTAAHTHRIIRICKRQGVPIVADRTTGIKHRPLQELT
                     PTRRTRNRSRPRHGHPSNTALPA"
     misc_feature    3678..3692
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            complement(3964..4413)
                     /locus_tag="DMB38_RS07770"
                     /old_locus_tag="DMB38_07780"
     CDS             complement(3964..4413)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMB38_07780"
                     /product="hypothetical protein"
                     /protein_id="WP_125934534.1"
                     /transl_table=11
                     /translation="MERKKTFVAGIAASIAVLAFMAGPAYAQSADPAAEISRQAPTGAV
                     GVLDTKCGGPSNGELCVNLFRDSQGQGILVRYDKCCGSEVTARVGWKRAGSSDSTATWD
                     STWYKVERNEYIVRTWRVSYPCNYEYEGLLQVSGQGIFRTPDTAC"
     misc_feature    complement(4360..4362)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4445..4460)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.61"
                     /tool="antismash"
     gene            complement(4468..4878)
                     /locus_tag="DMB38_RS07775"
     CDS             complement(4468..4878)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_125934535.1"
                     /transl_table=11
                     /translation="MRRQITLTAAALVAAGAALVSTPTAAAPTAAKPEAAEIQIPERCK
                     VLSNGKLCVRLLEEPERIQVFYQKVSGSKITARLGLKTETSRTRWDEWHSVAAGDILSQ
                     VWKSSWGCFAEGWVGVLQVEGVGTFQTPPTSC"
     misc_feature    complement(4890..4903)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     misc_feature    complement(5067..5081)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     gene            <5121..5446
                     /locus_tag="DMB38_RS07780"
                     /old_locus_tag="DMB38_07785"
                     /pseudo=""
     CDS             <5121..5446
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377440.1"
                     /locus_tag="DMB38_RS07780"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DMB38_07785"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SLPGRTHDLTAAHTHRIIRICKRQGVPIVADRTTGIKHRPLQELT
                     PTRRTRNRSRPRHGHPSNTALPA"
     gene            complement(5852..6382)
                     /locus_tag="DMB38_RS07790"
                     /old_locus_tag="DMB38_07790"
     CDS             complement(5852..6382)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMB38_07790"
                     /product="hypothetical protein"
                     /protein_id="WP_125934537.1"
                     /transl_table=11
                     /translation="MWLFILGGGTAGVGFAMGGPAVALIALAVPAVAALLGWGSLRSNR
                     IVVTPHEIAVLGLFVRRRGQRVRAASVVRADVIQQRGGLIFDTVFVLDAAGAVVIRINA
                     NNYEPADIDLLVRSLGLPWNGPDAPVTAPQLSSVYPGMVPWYEAHPVQFAMAGTGAAVL
                     FAVVLTILLQLSL"
     misc_feature    complement(6642..6657)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.68"
                     /tool="antismash"
     gene            complement(6804..7133)
                     /locus_tag="DMB38_RS07795"
                     /old_locus_tag="DMB38_07795"
     CDS             complement(6804..7133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985255.1"
                     /locus_tag="DMB38_RS07795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07795"
                     /product="hypothetical protein"
                     /protein_id="WP_125934538.1"
                     /transl_table=11
                     /translation="MALVKKGSRRITVDGVPYRWRVRARPTYGQGLVWSPLIYAVEQAG
                     TRGTILVVTTNQPHPSNWFEIPGRPVLPAEVAATIRMARAAGWTPDEPGSPFLLDRSQG
                     FVPAG"
     gene            complement(<7235..7475)
                     /locus_tag="DMB38_RS36675"
                     /old_locus_tag="DMB38_07800"
                     /pseudo=""
     CDS             complement(<7235..7475)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544239.1"
                     /locus_tag="DMB38_RS36675"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DMB38_07800"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGETTSSIGEGSAMRVSLSCPEGPQRRFGRESASGSSPRSSPRLS
                     SVSCVGRSLTSTWRDYESRRGADLRAGTAAGAGGL"
     misc_feature    7809..7827
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    7902..7913
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.19"
                     /tool="antismash"
     gene            8131..8841
                     /locus_tag="DMB38_RS07805"
                     /old_locus_tag="DMB38_07805"
     CDS             8131..8841
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851350.1"
                     /locus_tag="DMB38_RS07805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07805"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_125934539.1"
                     /transl_table=11
                     /translation="MELRFETRRSDSPWVDTVWSCTSEQVTAMTSVAGVHWGLVFWRQD
                     GRAYAGVTGPETRTGTAPVPEGAEFTGIEFALGTSLRALPTPALVDGGVELPDTTRRTF
                     RLDGARWETPRADDAEALVGRLVRAGIVVRDPLVAEVLRGHRPAVSERTVERRFRAATG
                     LTRGAVRQIARARTAAELLALGAPAASVVAKLDYFDEPHLARALRSYVGRTARQLREGA
                     GGAIALHPDQRLTS"
     gene            complement(8823..9401)
                     /locus_tag="DMB38_RS07810"
                     /old_locus_tag="DMB38_07810"
     CDS             complement(8823..9401)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018843837.1"
                     /locus_tag="DMB38_RS07810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07810"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_125934540.1"
                     /transl_table=11
                     /translation="MRDLVYTAFISLDGVVDSPGGGPGEEHRSGGWVVKDLEFVPEAWS
                     LKGEELADTTALMFGRRSYEAFAPVWPGSEDHAAYKELPKYVVSTTLSDDDLVDGWGPT
                     TILRSTEDVAALKEGEGGAIFIHGSAELARRMSDAGLIDQYNLLVFPVLLGAGKSLFGR
                     ADRDKQMLTLRESETYSNGIMKLIYDVRR"
     gene            9685..9894
                     /locus_tag="DMB38_RS07815"
                     /old_locus_tag="DMB38_07815"
     CDS             9685..9894
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018839775.1"
                     /locus_tag="DMB38_RS07815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07815"
                     /product="hypothetical protein"
                     /protein_id="WP_206337659.1"
                     /transl_table=11
                     /translation="MRRLTLSLATAALALGALLGASTAAAAQEPPIPAGLCVDGGGKVV
                     HDGTTPPIGYKCEGGRFDGFPVVL"
     gene            complement(10001..10990)
                     /locus_tag="DMB38_RS07820"
                     /old_locus_tag="DMB38_07820"
     CDS             complement(10001..10990)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="DMB38_RS07820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07820"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_164715937.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.8e-42, bitscore:
                     142.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6.3e-23,
                     bitscore: 80.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTRELVAAGVRTGALVEAYTCCGKFLSRNNSAAYPAARALLYPA
                     IRPYYDAILAFCGYADELLDDEATPISEREAAFDAWTAAFFDGSYEPDTDGAHSLDGRQ
                     GRLISRAFRHVIDTYGIELESVREFLHTMRGDLHVTSYATYADLNGYMSGISGVHAGWM
                     NALLETRHDDAQRIASSLGYGVYLLDFLADLREDLELGRVYLPTEDLERFGLDRAGFEQ
                     IVSRGVMTPSLRELVQFETVRVGQYFETADAWWRHVHPSSRELPRQYLALGRLSLQQLI
                     RSDYDVFRNRPRGWLLGTARARAGTGVSYLRARRDHRRHARGSAAVPT"
     gene            complement(11072..12205)
                     /locus_tag="DMB38_RS07825"
                     /old_locus_tag="DMB38_07825"
     CDS             complement(11072..12205)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023417.4"
                     /locus_tag="DMB38_RS07825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07825"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_164715938.1"
                     /sec_met_domain="indole_PTase (E-value: 4.3e-107, bitscore:
                     356.9, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDARSSRIPDARLRPETTFTEYTIPTLKRLLAATGLDAESGAATV
                     RNMLASWGDQPIGTEPIWGSFITTDTSPVEFSAAFGRTGTEVRVCVEAQPSRATTADAQ
                     DTASRLTRRLVDHAGISTRKLDVIRDLFLPEQDAHGWAMAHAVGLSEKSAPAFKVYLNA
                     NASPAMTPDDRVRAALERLGFGRVWEPLRAFADRGSDLDPVVYISLDLSDAPDARVKVY
                     FLHRHITPALWDSKLAAFPEHRAGSVEEFATELTRYTGAQPVITNFTFTARGGQRPESA
                     TAYVPLWHYVPNDQVACDRVRRALATHEIPDQDYQALLAQVARKPLDESWGIHSFASMR
                     TGRSGSPITVYLSPMFYGKSLITRREITELFPDLDET"
     gene            complement(12308..13141)
                     /locus_tag="DMB38_RS07830"
                     /old_locus_tag="DMB38_07830"
     CDS             complement(12308..13141)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (12-224). E-value: 6.9e-38. Score:
                     121.8. Matches aSDomain:
                     nrpspksdomains_DMB38_RS07830_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014627611.1"
                     /locus_tag="DMB38_RS07830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07830"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_125934544.1"
                     /sec_met_domain="PCMT (E-value: 4e-06, bitscore: 25.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQRPARTEESDDKFFDSLTGILAEAYGSHLHFGYWDASGDGSLA
                     AATSCMTDQVIKRTRVRAGQRVLDIGCGTGAPALRLAHVCGVEVVGVSVSAREVDRANE
                     RSRREGLAHRVRFESADAMALPYADGSFDAVWAIESMSHMPDRGRVFCEIGRVLAPDGR
                     LVIADGYHRGADPEASSALMDTMCTAFRMHSPPTLTGYEDLLTAAGLRTLETLDLSDHA
                     WRSIGYLTETLRARSPEFAHVLGEAAFTHLMECLKEADAAEIFGYVLLTAERKGL"
     aSDomain        complement(12470..13105)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DMB38_RS07830_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="6.90E-38"
                     /label="DMB38_RS07830_oMT.1"
                     /locus_tag="DMB38_RS07830"
                     /protein_end="224"
                     /protein_start="12"
                     /score="121.8"
                     /tool="antismash"
                     /translation="DKFFDSLTGILAEAYGSHLHFGYWDASGDGSLAAATSCMTDQVIK
                     RTRVRAGQRVLDIGCGTGAPALRLAHVCGVEVVGVSVSAREVDRANERSRREGLAHRVR
                     FESADAMALPYADGSFDAVWAIESMSHMPDRGRVFCEIGRVLAPDGRLVIADGYHRGAD
                     PEASSALMDTMCTAFRMHSPPTLTGYEDLLTAAGLRTLETLDLSDHAWR"
     gene            13521..14363
                     /locus_tag="DMB38_RS07835"
                     /old_locus_tag="DMB38_07835"
     CDS             13521..14363
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995049.1"
                     /locus_tag="DMB38_RS07835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07835"
                     /product="phosphotransferase"
                     /protein_id="WP_125934545.1"
                     /sec_met_domain="APH (E-value: 1.1e-11, bitscore: 43.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEPWELGRAVDAAQATAAELGLRADDAVTIHNSDRVVLRLLPCDV
                     LVRVAPSEHLADSRFEVEVARRLADVDAPLAELEPRAEPRVYVHGAFAVSLWRYYEPVG
                     AEISPADYADALVRHHAALRRIDLDAPHFTDRVAGALREVNDTERSPELPDADREFLSG
                     TLSGLSAAISAGSSGDQLLHGEPHPGNLLNTRRGPLFVDLATCCRGPVEFDLAHAPEDV
                     GMHYAGADPALIHRCRALGWAIFSAWRWRQEDQMPDRAHWRTEGLRRVRTALEPRGPG"
     gene            14469..18956
                     /locus_tag="DMB38_RS07840"
                     /old_locus_tag="DMB38_07840"
     CDS             14469..18956
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851005.1"
                     /locus_tag="DMB38_RS07840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07840"
                     /product="DUF6531 domain-containing protein"
                     /protein_id="WP_125934546.1"
                     /transl_table=11
                     /translation="MGNRPTDWHVLDLDDDPTPGDPERVKQLARELHDFADDVADALRQ
                     IKGMAGEDALLRWAGKTAKAFQDEFEEVPKNLKKLQRSYDLAGDALAAYWPKLERAQSL
                     ADKALAKGREAQSDLTAANGRLDSANSWVDRATKKTEEYDGKEGKEKPDESEVRAATRN
                     ATDAKSARASAQTAVDNAQGGLEAAKKMAADAKKMREDAASEAKDKLEEASDAGIQNRK
                     WWEKAVDWVKDNWDTIVNVCKVIVAVLGIVVLIIGGPLAWVVLAAALVVLADTLYKYMN
                     GEASLWDVAFAALDCIPGMKGLTTLGGLAKMAKGGMKAMAGLRAMKAGVLGLAKRGRTM
                     LGDAAQGARNRLRNVVNKLTDPVDLATGEMYLAQTDVELPGLLPLTFSRRLGSSYRCGL
                     WFGPTWTSTVDQRLEIDEDGIVFITEDGRLLAYPHPHGTDEVLPESGPRWTLARLETGG
                     YTITDPLTGHIRHFHAPVSDDVALLHRISDRNGHMVTFAYDADGVPTDIRHSSGYHLRL
                     TAEGDRVTALHLANAAGDGSDVEVKRFGYDAAGNLTEDCNSSGLPLTFAYDDRLRVTSW
                     TDRNDRSYSYTYDEHDRCTAEGGEAGHVALTLTYGGEDPAWPACTVTALTTADGATTRF
                     VVNDNSQVVAEIDALGHVSRTEYDRHHNLLSETNALGHTTRYENNSLGQPTAITHPDGS
                     VVRYEYDESACHTATLMPDGTAWRWEYDARGNLVSQTDPSGATTRLTRDDGGRLTGRID
                     ALGHTTRVRCVPAGMPEEVADPLGAVMRFRYDAFGRTSHVTDPTGVNESLTWSVEGHLV
                     RRTRAGGPAETWTYDPEGNCLTQVGADGATTRFEYTHFDMLSARVEPDGTRHEFTYDAG
                     LRLTEVRNPQGQSWHYRFDPAGRMVAEEDFDGRTLTSTFDAAGQLVARTNAAGETVTFG
                     YDPAGRIAHKTVGELTTVYAYDSAGRLRSAANPQSSLVYLRDAMGRIVAETVDGRTTTY
                     EHDLLGQRTRRTTPTGLTTHYAYDAAGRGTSVTTNGHTTDLVFDAAGRETERHLGALTV
                     NSAWDSAGRLARQSVTAGPERRIAQQRSYAYAPDGNLAGLDDRLNGDHRFGLDAVGRVT
                     SVTAPGWAESYAYDSLGNLTHGTWPTGNGHDAALGERTYTATTLTAAGTYRFRHDAAGR
                     LVTRTRKRLSKSPETWHFAYDAEDRLTGARTPDGVRWAYRYDPLGRRTAKQKFTADGRG
                     VAEETVFTWDGPVLIEQTSTGGPFPQPVTLTWNHQGLVPITQTERITDATTQDEIDARF
                     FAIVTDLVGTPRELLTPEGDIAWRTHTTLWGTLSWPSGSTAHTPLRFPGQYADPETSLH
                     YNLFRYYDPANARYTTPDPLGLAPAPNPVAYVHNPHTWTDPYGLAPYIHASVASSDWGN
                     KGAHVHIGSREVRVFPDGAGGVGGEPIRLSNGNVASPRDVERVLEEIRVNPKMREDLIA
                     KASSARASMNAGEYGTKVNRALEIHFLIKALEKM"
     gene            19036..19545
                     /locus_tag="DMB38_RS07845"
                     /old_locus_tag="DMB38_07845"
     CDS             19036..19545
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DMB38_RS07845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DMB38_07845"
                     /product="hypothetical protein"
                     /protein_id="WP_125934547.1"
                     /transl_table=11
                     /translation="MWERALPGDHLEDRRKKFMRWDYGLVEVFFARVDRQWSGSGFTIQ
                     VHRLAEAGGGPVPACLRDAYGDFRSSVPLGELTDSLAAAGLSLTEVESYSDREFSQFTS
                     PSGRVAVYVLTDPRPDADYRIPRGGSGRSRWRPRRRERSAGGECRQVDLIRSHWSTPCL
                     GADQGD"
     gene            19644..20375
                     /locus_tag="DMB38_RS07850"
                     /old_locus_tag="DMB38_07850"
     CDS             19644..20375
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838566.1"
                     /locus_tag="DMB38_RS07850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07850"
                     /product="chitinase"
                     /protein_id="WP_206337803.1"
                     /transl_table=11
                     /translation="MLAIGALAAALAVVVPVTASAGEGGTAGEGGADKAVAAEFIVSEA
                     QFEQMFPGRNAFYTYQGLTDALSAYPAFANTGDETTKKREAAAFLANVSHETGGLVHVV
                     EQNQDNYPHYCDASQPYGCPAGQAAYYGRGPIQLSWNFNYKAAGDALGIDLLNDPWQVE
                     RNAAVAWKTGIWYWMTQSGPGSMPAHDAITGGHGFGETIRAINGSLECNGGNPGQVQSR
                     IDKYTQFVQILGTTPGDNLSC"
     gene            20504..21535
                     /locus_tag="DMB38_RS07855"
                     /old_locus_tag="DMB38_07855"
     CDS             20504..21535
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018853759.1"
                     /locus_tag="DMB38_RS07855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DMB38_07855"
                     /product="chitinase"
                     /protein_id="WP_125934549.1"
                     /transl_table=11
                     /translation="MARARTHKFRKTRKRLVGALAAASLTAGALAAAVATEAAADPEPV
                     THGAAAVPAHAVTGYWQNFDNGATVQTLADVPEAYDIIAVAFADATGTPGQVDFTVDPA
                     LDYTEDAFKADVAAKQESGKSVVISVGGERGAVSVNDEASAEAFATSILGLMEEYGFDG
                     VDIDLENGLDSTYMTQALKAIHAGAGDGLVVTMAPQTIDMQSPENEYFKTALNIKDFLT
                     VVNMQYYNSGSMLGCDGKVYSQGTVDFLTALACIQLENGLAPSQVGLGTPASSRAAGGG
                     YVEPGVVTDALDCLTRGTGCGSFKPEKTYPELRGAMTWSTNWDAADGNAWSDTVGPHVD
                     QLP"
     misc_feature    20528..20544
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
ORIGIN
        1 cgaagacccc ttcgccctcc atcgaccggc gtcacggcag gctgctgagg ttggcggttt
       61 cgccgtgact gccggttaca gccgacatcg ccgaccgctg ttcgcttgtg cattgctgat
      121 gaccccggcg ccgccgaacg ggggctcaat cggcgccggg gtcctgtcgg ccccggcgcc
      181 gcttaacggg ggtatgggcg gcgtcgtcag gccgacgatg gtggagcgga gatgaactcc
      241 gctatagggt ggccaggctg taggtggcgc tcgttccggt ctgctctccg gtgtcgactt
      301 gctccgactc gccatcgcac acagtccagt tgtcgctgta acggccgatc cgtacggtca
      361 ggcgcgtgca ttcgccgtcg tccaggtgct ctgcaactgt ccggtcaccc gaatcgtgcc
      421 gtcgtccgtg caactggtaa gcgtggcccg ggcgccagag ccgacgacag cctgcgtggt
      481 gcaggccgcc gtcttcgcga agggaatgcc gtcggcgagg gccggggcgg cggtagcggc
      541 cataatgccc tccggtggcg acggcgacga cgcccaggat ccttgagatg atgcgcaatg
      601 cctggcagac cgcgcgtgac cctcgccatg cgcgtgcgac cggcgccgcg ctccgtggag
      661 cggcaccagg cccgacaatt cggtgtgggg atcagtcagg ggaaagtcgg ctggttgagg
      721 caggactccg aactcccgcc gttggtcagc ttgtcgttgc ggatccaccc gtacgagctc
      781 ttcagatccg gatcggcggc ggtgaaccgc acgtgggtcc agcggtaccc gttgctgtcg
      841 cggctgtcgg tcgcgcagtg gtagtcgagg ccgtcgttgc tgtccacaac tcggacccga
      901 ccgcatgtgt acgcaggacc ggtgtgctgg cccgtatccc acttggcata gctgccattg
      961 ggggtcgggt cgagatcctg ctgcgtctgg tagtcgctac agagagcctt gacggtcatc
     1021 tcatcgctgt cggcggcgtt cgccgccccg gacgtgagca gcgccgcggc ggcgacaaga
     1081 ccggcgccga aacccgcggc acgtcgttgt actgttgcca tgagtcatcc tccgtatgca
     1141 gaagcggaac tccctgatga ggccacggtg gcacggcctc atcgagtatg cggccggcac
     1201 cttgtacgcc atcgtgaagc gacctgacgc ggccgccacc tactcaccgg cccggccgag
     1261 accgcccgcc gagcgaggag cgccgcccgc ggccggccgt tgtcaaggct ggccaccgag
     1321 atgagggccg gctccgcccg gcgatgccag gtaggggcat gcctgatacc aggcgtggcc
     1381 tggcgcacca cggcctgact tctcgcggac ggccccccgt tcatcggtaa gcccgcggcc
     1441 cacgcgaacc tcacgcatcc ggcataccgc cgcgatcatg aggcatcagc ccgcacgaca
     1501 ccagctttga agctcagcag gtgtggagtc tcgcgacttc agcaacacga aacgccatac
     1561 caggagttgt cattcgatgg gccgttctca cgagctgtaa gggttccggc cgccggtctg
     1621 cggctgctgc tgaggtgcgg gctcctgggc gaaagggttg ccggtatcct gctggggcga
     1681 cgactgcggt gccgcctgca gttggaactg ctcggactgc tccttggtta tctggcccga
     1741 cgccccacag aacgtgcact gggtgaagta ttttgtcgag acagggaaca gcgggatgaa
     1801 gaacagcgtg aacttcgtga cccgcttgag caggctgtgt gccgccgggt tcccgcacat
     1861 gccgcacaag aggttgatca cggcgagctg gaccgcggtg ctccgggtgc caaagatgat
     1921 cattgttctg tccgttcctt cgggagtacc gtctcgcgat cctcggggtg agtgattcat
     1981 cgtcgtggag agtgaggaat ctctggccgg tgacccgtca acggtataca ggattcgaac
     2041 gggcacgtca ctcacttcgt tcgaccacag cctctgagtc cgccacctgt ccgacaccgg
     2101 tccgtccgcg gccaacgagc cagcggtcca tcacgtcgcc ggtccgcgag acccagatca
     2161 atccctgccg caaaggccgc tccccgggag gcctgcatct gcgtgtcagg tggcgtactg
     2221 cttccaggag gtgcagctga aggcgctgac agcttcgcac acacggaaga agacccactt
     2281 atcgccgtcc ggattgctta ccggatacga gtcgtagccg gacatgtcct tcggatggta
     2341 gatccacttg ttgggtgtgt ggtcagcctt gtacgagtac tggacggcac actgcttgcc
     2401 gttgacgtcc gtgtcccaga tcaggaacat acggggcgac gaaatccaca ttacatcaca
     2461 gccgccgtac gggatggtcg gtgagtccgc ggacgccggt ccaaccgtgc ccaacgcaat
     2521 cgccgcggcc gcaatactca ccgcggccgg ctccaccaca cgctgtgcca gcgccttcat
     2581 tgttatcccc tcacgcaaaa ccttgcccgt cgcacgagcc tgttcccgga gcatcccagg
     2641 acgaccttga tgggaacttg acgggatcag acgccgattg ctgctgcccc gggcagtatc
     2701 cgcccatgtc cttgaccgac ctgagtagca gacttcgcga cgcagatcag ccgacgcgtg
     2761 tccaaggtgc tgcccgtgat cgacttgcgg acgcccgaga gccgcaggag tgccgctatc
     2821 tcatgcggtt ctgccggcaa ctgaccatgc accaccagga gcggcaatgc tgcccggccc
     2881 gggcccggca gcctcagacg gccgacatcc cgctctttcc gtagcgcggc tcccacagcc
     2941 tgcggttgac gacgcgcacc ggcggtggga ggtgtgcgag gaatcgctcc cggtcggcgg
     3001 caggcatcga gtcggtgatc cacggtacgt agaccgccgc gccccgtatg ccctggcgct
     3061 cgcgcatcct gcttgcgaag acgcgccagt cagccggtgt cagcacttct tggatgagcg
     3121 gcagtgcgct cttctcctcg tgatcgaggc gctccacgag cgacttcctc cggcggtcca
     3181 cctgctcgac gaggtcggcg gccggttcct ccagggccgc ctcgacggag gccagcagct
     3241 ggtcgatacg ggcgtgctcg gcctccatgt ccgccagcag gagccggtag tcgggcgggt
     3301 gcgccacctt atccgtcggg cgcggccaca gaacgtcgtc ctccacggtg tggtggagca
     3361 gcagttggtg cttgaagttc gaggtcatgc gggtggggct gcatcgggag cggcgggaga
     3421 tccgccatga tttcaggcgg gcaacgccgt gttcgacggg tgcccgtgcc gcggccggga
     3481 ccggttgcgg gttctccggg tgggggtgag ttcctgcagg ggcctgtgtt tgatgcccgt
     3541 ggtccgatcg gccacgatgg gaacgccctg gcgcttgcag attcggatga tccggtgggt
     3601 gtgggcggcg gtcaggtcgt gggtgcggcc cggcagtgat cgatgaccaa cgaggccccg
     3661 agcaagatga ttgagacgtc agacatctcg atcaacagcc cggggcgcct cgctcgtcgc
     3721 cgcccgcgaa ccgtcacctg atcggtgacc acctcgaaga agctcactga cggccagtgc
     3781 acagttttca gacggtgcgt tcgccccggc caaggacggt ggcaactgtg gcaacagggc
     3841 cttccggcac tcggtcggaa tcgcgctccg agccaccgcg gggccctgcc tcatgccgcc
     3901 gttacgtgaa gaccacacga gccggcgtcc gttcgatcac cacgtcgggc cggtcacacc
     3961 aactcagcag gccgtgtcgg gggtacggaa gatgccctga ccggacactt ggagcagccc
     4021 ctcgtattcg tagttgcacg ggtagctgac gcgccacgtc cttacaatgt actcgtttct
     4081 ctccactttg taccaggttg aatcccaggt ggccgtgctg tcgctgctgc ctgccctctt
     4141 ccagcccacc cttgcggtga cctcactgcc gcagcacttg tcataccgca cgaggatgcc
     4201 ctgtccctga gaatcccgga acaggttgac gcagagttcg ccattgctcg gcccgccaca
     4261 cttcgtatcc agaactccca ctgctcccgt gggagcctgg cgtgatattt ccgcggcggg
     4321 atcggcgctt tgcgcgtacg ccgggccggc catgaaagct aagacggcta tcgacgccgc
     4381 aatcccggcc acgaacgtct tctttctttc catctctatc ctcgcaatca gcgggtgttg
     4441 tgaggtgaaa gaactgataa tcgagtatca gcagctggtc ggcggggtct ggaacgtacc
     4501 caccccctcc acctgcaaca ctccgaccca tccctcggcg aaacatcccc agctactttt
     4561 ccacacctga ctgaggatgt ctccggcagc gacggagtgc cactcgtccc acctggttct
     4621 cgaagtctca gtcttgagac cgagccgggc tgtgatcttg cttccggaga ccttctggta
     4681 gaagacctgg attcgttcgg gttcttcgag aagcctgacg cagagcttgc cgttactgag
     4741 gaccttgcac cgttctggaa tctgaatttc cgccgcctcc ggtttggctg cggtcggcgc
     4801 cgcggccgtc ggcgtggaaa cgagagccgc gcctgcagca acaagggctg ctgccgtcag
     4861 ggtgatttgt cgtcgcattc atccctcaag tgatccgcct cgattgacct ggtagcaggg
     4921 taagaagaaa cacacccgca ggccaatatg cacggcgctc aattccgggc gctggttgtg
     4981 cacagtgctc agtgagcttc ttcgaggtgg tcaccgatca ggtgacggtt cgcgggcggc
     5041 gacgagcgag gcgccccggg ctgttgatcg agatgtctga cgtctcaatc atcttgctcg
     5101 ggggcctcgt tggtcatcga tcactgccgg gccgcaccca cgacctgacc gccgcccaca
     5161 cccaccggat catccgaatc tgcaagcgcc agggcgttcc catcgtggcc gatcggacca
     5221 cgggcatcaa acacaggccc ctgcaggaac tcacccccac ccggagaacc cgcaaccggt
     5281 cccggccgcg gcacgggcac ccgtcgaaca cggcgttgcc cgcctgaaat catggcggat
     5341 cttccgccgc tcccgatgca gccccgcccg catgacctca accgccaaga cccttctcac
     5401 ctcggagctg caacgccgaa gaggctcact gaccaggcaa ggctaggaac gatcagtgcg
     5461 gccacgtcgg tgccggggac ggtgacggtc tgctcgtcga gggcgctgaa gatctcctcg
     5521 gtcagccgaa ccactgtgcc ttcggccgcc gttctggaac gtccggggaa ctgtggccac
     5581 gggttcctgc ggaacggctt gacgctttgc tctcgagtct caccccggct cacccgcaca
     5641 ccttcccgac catcagccag agggtgcgtg cttgtgcaag gccgcactgg cacggaaccg
     5701 aagtcttccg caacggtccc tgtcctcatc cgtagcgccc tcgccgcggt agcagtgccg
     5761 ggccagccag ctcaggtcct gcggatcagt gggctctgga gttttcacgg gcccgactgt
     5821 acgtgccgat cccgacgagg gcgccgatgc atcagagaga aagctgcaac aggatcgtca
     5881 gaacgacggc gaatagcacg gcggcgcccg tacccgccat ggcgaactgg accggatgtg
     5941 cctcgtacca gggcaccatg ccggggtaga ccgaggagag ttggggcgcg gtcacaggtg
     6001 cgtcggggcc gttccacggc aggcccagag accggacgag aagatcaatg tccgcaggtt
     6061 cgtagttgtt tgcgttgatg cggatcacga ccgcaccggc ggcatcgagt acgaacaccg
     6121 tgtcaaagat cagtccccca cgctgctgga taacgtcggc ccgaacgact gacgcagcac
     6181 gaacgcgctg cccgcgccgt cggacgaaca agccgagtac ggcaatctcg tgcggagtca
     6241 cgacgatccg gttggacctc aaggatcccc agccaaggag cgccgcaacg gcaggcaccg
     6301 caagagcgat cagtgcgacc gcaggaccac ccatggcgaa cccgacgcca gcggtgccgc
     6361 cacccaaaat gaacagccac acacacagga agatgagctg cgtccgggag tggtttctgc
     6421 gagccgggcg cagtacgagg tcgccgtatc cgtacaccgt tctccaatcc gcgacaccgg
     6481 ggagtgcacg ccacgcaccc gcactacctg ggcctattcg taccgccggg tggctggaag
     6541 cctggtgcaa gcgccacggc tatagcggcg agtgcccggc agcgtcctga tcgaacgtct
     6601 tcactcccgg ctcagcaaga gcgtgatcga gcagctcgcc caagtccagc cggtcaagag
     6661 catccgggcg acgatcagga ggacgctcga tgtgggcatc gccgcctacg ccgacaacag
     6721 gcgacacgcc ggcgactggg ccgcgaaaat ctacaacggc gccagggaga tgtcgaacgc
     6781 cgtcggtacg acgactgcgc cggttatcca gcaggcacga agccctggga acggtcgagc
     6841 aggaaagggc ttccgggctc gtccggcgtc cagccagcgg cgcgagccat gcggatcgtg
     6901 gcggccacct ccgcgggcag caccggcctg ccggggatct cgaaccagtt gctcggatgc
     6961 ggttggttgg tggtcaccac gaggatggtg cctcgtgtcc cggcctgctc aacggcgtag
     7021 atcaacggac tccacaccag cccctgacca taagtcggtc gcgctcgaac cctccatcga
     7081 taggggacgc cgtcgacggt gatgcggcgt gagcccttct tgaccagcgc catggcctcc
     7141 tcctttccgc ccgatggaca gtaaccgcca gccccggtcc gtgaccgcag cctactggtg
     7201 tggctacgcc agacgcagtg agtctcgttg ttgcgaagac ctcccgcgcc cgctgccgtg
     7261 ccggctcgaa gatcggctcc cctgcggctc tcatagtccc gccaagtact cgtcaaggac
     7321 ctgcccacgc agctcacgct cgacagcctc ggcgatgaac gcggagaact cccacttgcc
     7381 gactcgcgcc cgaatcgccg ctgcggtccc tccgggcacg acaggctcac ccgcatcgcc
     7441 gagccttccc cgatgctgga cgtcgtttca cccatacccc ccgaaaagca ccacgctcga
     7501 tgccgcccgc aggcatcgag cggcaggtat cccagcacgg tacggatgac cggggatgac
     7561 gacagatgac gaggggtcag ccatccctgc acgggaaaag gctaagggcc caccgacctc
     7621 gaagagccgg cccctcgctg acctgcatgt ttgtcaaatc agcgacgtgg cgctacatca
     7681 ccggctacac cctgaagcgg aactccacca cgttcgcgac cacaccttcc acgaggacgc
     7741 cctcgaagat ccgcacccgc acttgccccg cgtcatggcc ggcctctgaa ggtcctgacg
     7801 aacccggaga tgagatcact cctcaaagac cctgcacacg cctggcgcct ctgtgttcga
     7861 cagcagggcg ccgtgcccca gggcgttctt cctgatcgac ggcaaatgtt ttcacgggca
     7921 gtccgctatg tgtaatggac cgtagtgaag catgagaaac gccaggtcag gcgcaagaac
     7981 gcgagaggca caactggccc cggcgtacag gccgactcgt ccgcctctcc ccctccggcc
     8041 tgccggtttc ctgaggccag gaagatcctg cggggattcg cgatccgtcc ggcggggtgc
     8101 gtcggccgcg gcgcgcctta tccttcgccc gtggagctgc gcttcgagac ccgccggtcg
     8161 gattcgccct gggtcgacac cgtgtggagt tgcacgagcg agcaggtcac ggcgatgacg
     8221 tccgtcgccg gggtgcactg gggcctggtc ttctggaggc aggacggccg ggcgtacgcg
     8281 ggcgtcaccg gtcccgagac ccggactggg acggctccgg tgccggaggg cgcggaattc
     8341 accggcatcg agttcgccct gggcacctcg ttgcgggccc tgcccacgcc cgcgctggtc
     8401 gacggcggcg tcgagctgcc cgacaccacc cgccggacgt tccgtctgga cggcgcacgg
     8461 tgggagacgc cccgcgccga cgacgccgag gctctggtcg ggcggctcgt ccgggccggg
     8521 atcgtggtcc gtgacccgct cgtcgcggag gtgctgcggg ggcaccgccc ggccgtctcg
     8581 gagcgtacgg tcgaacgccg gttccgcgcc gcgaccgggc tgacacgggg ggccgtccgg
     8641 cagatcgcgc gggcccgtac cgcggcggaa ctgctggccc tcggcgcgcc ggccgcttcc
     8701 gtcgtcgcca agctcgacta cttcgacgag ccgcacctgg cccgggcgct gcgctcctac
     8761 gtcggacgca cggcgcggca gttgcgcgag ggcgccggcg gcgcgatcgc cctccatccg
     8821 gatcagcgcc tgacgtcgta gatcagcttc atgatcccgt tcgagtaggt ctccgactcc
     8881 cgcagcgtca gcatctgctt gtcgcggtcg gcccggccga acaggctctt cccggcaccg
     8941 agcagcacgg ggaagacgag caggttgtac tggtcgatca ggcccgcgtc cgacatccgc
     9001 cgggccagct ccgcgctccc gtggatgaag atcgcgccgc cctcgccctc cttgagcgcg
     9061 gcgacgtcct cggtcgagcg caggatggtc gtcggccccc acccgtcgac gaggtcgtcg
     9121 tcggagagcg tggtcgacac cacgtacttg ggcagctcct tgtaggcggc gtggtcctcc
     9181 gagccgggcc agaccggcgc gaacgcctcg tagctgcggc ggccgaacat cagcgccgtc
     9241 gtgtcggcga gttcctcgcc cttcagcgac caggcttccg ggacgaactc gaggtccttc
     9301 accacccatc cgccgctgcg gtgctcctct cccggcccgc ccccgggcga gtccacgacg
     9361 ccgtcgaggg atatgaaggc tgtgtagacc aggtcgcgca tggtgctgtc tcctcgtgat
     9421 caggcgagta ccgggccagg ctagatcgcg gccgcggcgg cggtcttgga cgaaaacgac
     9481 agcacgttga gccctcgggg caccgctcac ggttgtacgc cgggggcgtg gatggggcat
     9541 tcggtgcagt cgagccgcgg gtgcgctcgg tggatcgagt ggggttgacg gggatccgcc
     9601 atgcctgcgc gatcagcggg gacagggaga gtgatcacat cactccgggg agccgtgtct
     9661 cccctgtgac tcttggagga cgccatgcgt cgtctcactc tgtccctggc caccgcggca
     9721 ctggctctcg gtgccctgct cggcgcgagc accgccgccg cggcccagga gcctcccatc
     9781 cccgccggac tgtgcgtgga cggcggcggc aaggtcgtcc acgacggcac caccccgccg
     9841 atcggctaca agtgcgaggg cgggaggttc gacgggttcc cggtggtcct ctgacccgtg
     9901 aggccgtagg gagatgaggt ctgctgctgc ccggggcgcg ccccgggcag cggcggctca
     9961 ccgtacgggt gtgggggaac ggcctcgtga acgtgggctg ttacgtgggg acagcggctg
    10021 agccacgggc gtgcctgcgg tggtccctgc gtgccctgag ataggaaacc ccggtaccgg
    10081 cgcgggcgcg ggccgtgccg agaagccagc ctcgcggacg gttccgaaag acgtcgtaat
    10141 cagagcggat gagctgctgg aggctgaggc gtccgagggc caggtactga cggggcaact
    10201 cgcgcgacga ggggtggacg tgacgccacc acgcatcggc tgtctcgaag tactgcccca
    10261 ctcggaccgt ttcgaattgg acgagttcgc gcaaggacgg tgtcatgacg ccacgtgaga
    10321 cgatctgttc aaacccggcg cgatccagtc cgaaccgctc gaggtcttcc gtcgggagat
    10381 agacgcgccc cagttcgagg tcttcgcgga gatcggcgag gaagtccagg aggtacacgc
    10441 cgtatccgag cgaggacgcg atgcgctggg cgtcgtcgtg acgtgtctcc aagagtgcgt
    10501 tcatccatcc tgcgtgcacg ccgctgattc cgctcatgta cccgttcagg tcggcgtagg
    10561 tggcgtagga cgtgacatgg aggtcaccgc gcatcgtgtg gaggaactcg cgcacgctct
    10621 cgagttcgat gccgtaggtg tcgatgacgt gccggaacgc tcgggagatc agtcgtccct
    10681 gccgcccgtc gagagagtgc gcaccgtccg tgtccggctc gtaggagccg tcgaagaacg
    10741 ccgccgtcca ggcatcgaac gcggcctccc gctcgctgat cggtgtcgcc tcgtcgtcca
    10801 ggagttcgtc ggcgtacccg cagaaggcga gaatggcgtc gtagtacggc cggatcgccg
    10861 ggtacagcag tgcccgcgcc gccggatacg ctgccgagtt gttcctggac aggaattttc
    10921 cgcagcatgt ataggcttcg acgagtgctc ccgtgcgcac cccggcagct acgagttcac
    10981 gagttcgcac gcgttctccc agatgaggta tcggccgttt cgcttgcgat tgacgatcgg
    11041 atgagcccaa acttcgggtg tggtgcagcc gtcaggtctc atcgaggtcg gggaacagct
    11101 cggtgatctc ccgccgggtg atcagactct tgccgtagaa catgggcgag aggtagaccg
    11161 tgatcggtga tccactgcgg ccggtgcgca tggaggcgaa actgtgaatt ccccagctct
    11221 cgtcgagcgg ctttcgagcc acttgcgcga gcagcgcctg gtagtcctgg tcggggattt
    11281 catgggtcgc gagcgcacgc ctgacgcggt cgcaggcgac ctggtcgttg gggacgtagt
    11341 gccagagcgg aacgtacgcc gtggccgatt caggtcgctg cccgccccgc gccgtgaagg
    11401 tgaagttggt gatcaccggt tgcgccccgg tgtaccgggt gagttcggtg gcgaactctt
    11461 ccaccgagcc cgcgcggtgc tccgggaagg ctgccagctt gctgtcccac agggcagggg
    11521 tgatgtggcg atgcaggaag tagaccttga cccgcgcgtc gggtgcgtcc gagagatcca
    11581 gactgatgta cacgacgggg tcgaggtcgc tgccgcggtc ggcgaaggcg cgaaggggct
    11641 cccacacccg gccgaacccc agcctctcaa gtgcggcccg tacgcggtca tccggtgtca
    11701 tcgcgggcga agcgtttgca ttgaggtaga ccttgaatgc cggcgccgac ttttcggaaa
    11761 ggcccacggc gtgggccatg gcccacccgt gggcgtcctg ctcggggagg aacaggtccc
    11821 ggatcacgtc gagtttgcgg gtggagatgc cggcgtggtc gacgaggcgg cgggtgaggc
    11881 gggatgcggt gtcttgcgcg tcggccgtgg tggcgcgaga aggctgcgct tcgacgcaga
    11941 cccgcacttc ggtgccggtg cgaccgaacg cggcggagaa ttccaccggt gacgtgtcgg
    12001 tggtgatgaa agatccccag atcggttccg ttccgatggg ctgatcgccc caggacgcga
    12061 gcatgttacg caccgtcgcc gctcccgact cggcgtcgag ccccgtagcg gccaggagcc
    12121 gcttcagcgt ggggatcgtg tactcggtga atgtggtctc gggacgcagc cgggcgtcag
    12181 gaatccgtga actcctggca tccattcgca tgttcacctt ccgctttctg tcgacattac
    12241 ccgggtcccc agccgggccc ggcgggtccg gcccggcgat ggcatgcctc tccgccatgg
    12301 gctgctgtca aagccccttg cgttccgcgg tgagcagcac gtacccgaag atctcggcgg
    12361 catcggcttc tttcaggcac tccatgaggt gcgtgaaggc cgcctccccc agcacgtggg
    12421 cgaactccgg cgatcgcgcg cgcagggtct cggtcaggta gccgatcgag cgccaggcgt
    12481 ggtcggagag gtcgagagtt tcgagagttc ggaggccggc cgcggtgagg agatcttcgt
    12541 atcccgtcag agtcggaggg gagtgcatac gaaacgccgt acacatggtg tccatcaggg
    12601 cgctgcttgc ctctgggtcg gcgccgcggt ggtatccgtc cgcgatcacc agccggccgt
    12661 cgggagcaag cacacggccg atctcgcaga acacccttcc gcggtccggc atgtggctca
    12721 tcgactcgat cgcccacacc gcgtcgaagg atccgtcggc atacggcagc gccatggcgt
    12781 ccgcgctctc gaagcgcact cggtgcgcca gcccctcacg tcggctgcgc tcgttggcgc
    12841 ggtcgacttc gcgcgcgctg acggagacgc cgaccacctc cacgccgcag acgtgggcga
    12901 ggcgcagcgc gggcgcaccg gtaccgcagc cgatatcgag cacccgctgc ccggcgcgca
    12961 cccgggtgcg cttgatcacc tgatccgtca tacacgaggt ggccgcggcg agtgacccgt
    13021 ccccggaggc gtcccagtac ccgaaatgca gatggctgcc gtacgcctcg gcgagaatcc
    13081 ctgtgagcga atcgaagaat ttatcgtccg attcttccgt gcgcgcggga cgttgggcca
    13141 tccggctctc ctcaagagaa gaagtaagtg caccgtcatt acgacagatt cgaagtcggc
    13201 ttcgatttcc tctttcggca ggggagaccg gtgaacgtct caccggcgcc ggcgacactc
    13261 tcccctgaag gtattcactc gaatatcacg cgtgacacat ggaagcggag tcacttggtt
    13321 cccttgcgcg cccggggcgc acgacggagg tgccaccagg tgtggcatcg cctccggacc
    13381 acttgatcga ggggtttggc tcgatgccgt gccgggtgcc ggcctcgctc ccggcctgcg
    13441 gccggcgcca ccggagccgc cgtgctcgac tactctcggc ctggggtgtg cggggagcgt
    13501 ggacatgagg ggagggcggt gtggagccgt gggagctcgg gcgcgcggtc gacgcggccc
    13561 aggcgaccgc tgcggaactg ggccttcggg ccgacgacgc ggtcaccatc cacaactcgg
    13621 accgtgtcgt actgcgcctg ctcccgtgcg atgtgctggt tcgggtggcg ccttcggagc
    13681 acctggctga ttcccgcttc gaagtagagg ttgcccgccg tctcgccgac gtcgacgcgc
    13741 cgctggccga gctggagcct cgggccgagc cgcgcgtcta cgtgcacggc gctttcgcgg
    13801 tctcgctctg gcgctactac gaacccgtgg gtgcggagat ctcaccggcc gattacgcgg
    13861 acgcgctcgt acggcaccat gccgccctgc gccggatcga cctggacgca ccgcacttca
    13921 ccgaccgggt cgccggggcg ctgcgagagg tgaacgacac ggagcgttcc cccgaactgc
    13981 ccgacgccga ccgggaattc ctcagcggca cactcagcgg actgagcgcc gcgatcagcg
    14041 ccgggagttc cggagaccag ctcctgcacg gcgaaccgca cccgggcaac ctcctcaaca
    14101 ccaggagggg cccgcttttc gtggacctcg ccacgtgctg ccgcggaccg gtcgagttcg
    14161 acctcgccca cgcgccggaa gacgtgggaa tgcactacgc gggagccgat cccgccctga
    14221 tccaccgatg ccgagccctg ggctgggcga tcttctccgc ctggcgctgg cgccaagaag
    14281 accagatgcc cgaccgggcc cactggcgga cggaaggtct ccgacgggtt cgcaccgcac
    14341 tcgagccccg cgggcccggc tgaacgcgga acggccgtac cacagccgcc gacgcgcagc
    14401 gaaggaaccg ccccaacccg tgtgatcgtc aatgactacg gtgaccgagt ggcaaggggg
    14461 gagccggcgt ggggaatcgt ccgacggact ggcacgtact cgatctcgat gacgacccga
    14521 cgccgggtga tccggagcgg gtgaagcagt tggcgcgtga gctgcatgat ttcgccgatg
    14581 acgtggcgga tgcgttgcgg cagatcaagg ggatggccgg tgaggacgcg ctgctgcggt
    14641 gggcggggaa gacggcgaag gcgttccagg acgagttcga ggaagtcccg aagaatctca
    14701 agaagcttca gcggtcgtac gacttggcgg gtgatgccct ggcggcgtac tggccgaagc
    14761 tggagcgggc gcagtcgctg gcggacaagg cgctggcgaa gggccgtgag gcgcagagtg
    14821 atctgaccgc cgcgaacggg cggctggatt cggcgaattc gtgggtggat cgggcgacga
    14881 agaagacgga ggagtacgac gggaaggagg gcaaggagaa gcccgacgag tccgaggtac
    14941 gcgccgcgac ccgcaacgcc accgacgcca agtccgcccg cgcctccgcc cagacggccg
    15001 tcgacaacgc ccaaggcggc ctcgaagccg ccaagaagat ggccgccgac gcgaagaaga
    15061 tgcgtgagga cgccgcctcc gaggcgaagg acaagctcga agaggcgtcg gatgccggta
    15121 ttcagaaccg gaagtggtgg gagaaggcgg tcgactgggt caaggacaac tgggacacca
    15181 tcgtcaacgt ctgcaaggtc atcgtcgccg tcctcggcat cgtcgtcctc atcatcggcg
    15241 gacccctcgc ctgggtcgtc ctcgccgccg ccctcgtggt cctggccgac accctctaca
    15301 agtacatgaa cggcgaagcc tccctctggg acgtcgcctt cgccgccctc gactgcatcc
    15361 ccggcatgaa gggcctcacc accctcggcg ggctggccaa gatggccaag ggcggcatga
    15421 aggccatggc gggcctgagg gccatgaagg ccggcgtcct gggcctggcc aagcgtggcc
    15481 gcaccatgct cggcgacgcc gcccagggcg cacgcaaccg gctcaggaac gtcgtcaaca
    15541 agctcaccga ccccgtcgac ctggcgaccg gcgagatgta cctcgcgcag accgatgtcg
    15601 aactccccgg cctgctcccc ctcaccttca gccgccggct gggctcgtcc taccggtgtg
    15661 gcctgtggtt cggtcccacc tggacgtcca ccgtcgacca gcggctggag atcgacgagg
    15721 acggcatcgt cttcatcacc gaagacggac gcctgctcgc ctacccccac ccccacggca
    15781 ccgacgaggt gctgcccgag tcgggtccgc gctggaccct ggcccgcctg gagaccggtg
    15841 gctacacgat caccgacccg ctcaccggcc acatccggca cttccacgcc cccgtctccg
    15901 acgacgtggc tctgctgcac cggatatcgg accgcaacgg tcacatggtc accttcgcct
    15961 acgacgccga cggcgtcccc accgacatcc gccactcatc cggctaccac ctccgcctga
    16021 cggccgaggg cgaccgggtc accgccctcc atctcgcgaa cgccgccggc gacggctcgg
    16081 acgtggaggt caagcgcttc ggctacgacg ccgccggcaa cctcaccgag gactgcaact
    16141 cctcgggcct gccgctgacc ttcgcctacg acgaccgcct gcgcgtcacc tcgtggaccg
    16201 accgcaacga ccgctcctac tcctacacct acgacgagca cgaccgctgc accgccgagg
    16261 gcggcgaggc gggccacgtg gctctcaccc tcacctacgg gggagaggac cccgcctggc
    16321 ccgcgtgcac ggtcaccgcc ctcaccaccg ccgacggcgc caccacccgc ttcgtcgtca
    16381 acgacaacag tcaggtcgtc gccgagatcg acgccctcgg ccacgtgtcg cgcaccgagt
    16441 acgaccggca ccacaacctg ctctccgaga cgaacgccct gggccacacg acccggtacg
    16501 agaacaactc cctcggacag ccgaccgcga tcacccaccc ggacggctcg gtcgtccgct
    16561 acgagtacga cgagtcagcc tgccacaccg ccacgctcat gccggacgga acggcatggc
    16621 ggtgggagta cgacgcccgg ggcaacctcg tctcccagac cgacccctcc ggggccacga
    16681 cccgtctgac gcgcgacgac ggcggccggc tcaccgggcg gatcgacgcc ctcggccaca
    16741 ccacccgcgt ccgctgcgtc cccgccggca tgcccgaaga agtcgccgac cccctcggcg
    16801 cggtgatgcg cttccgctac gacgccttcg gacggacgag tcacgtcacc gaccccacgg
    16861 gggtgaacga gtcgctgacc tggtcggtcg aggggcacct cgtgcgccgt acccgcgccg
    16921 gcgggccggc cgagacgtgg acgtacgacc cggaggggaa ctgcctcacc caggtgggcg
    16981 cggacggggc aaccacccgt ttcgagtaca cccacttcga catgctctcc gcccgcgtcg
    17041 aaccggacgg cacgcggcac gagttcacgt acgacgcggg actgcggctg acggaggtgc
    17101 gcaaccccca ggggcagagc tggcattacc gtttcgaccc cgcgggccgg atggtggcgg
    17161 aggaggactt cgacggccgc accctcacca gcaccttcga cgcggccgga cagctcgtcg
    17221 cccgtacgaa cgccgccggc gagaccgtca ccttcggcta cgatcccgcg ggccgcatcg
    17281 cgcacaagac ggtgggcgag ctgaccaccg tctacgccta cgactccgcc ggccgcctgc
    17341 gctccgccgc caacccgcag agcagcctgg tctacctgcg cgacgcgatg gggcgcatcg
    17401 tggccgagac cgtggacggc cgcaccacca cctacgagca cgacctcctc gggcagcgca
    17461 cgcggcggac cactcccacc ggcctgacca cccactacgc gtacgacgcc gccggccgcg
    17521 gcacatcggt gaccaccaac ggccacacca ccgacctcgt cttcgacgcc gccggccggg
    17581 agaccgagcg ccacctcggc gccctgacgg tgaactccgc ctgggactcc gccgggcgcc
    17641 tcgcccgcca gtcggtcacc gcgggccccg agcgccgtat cgctcagcag cgctcctacg
    17701 cctacgcccc ggacggcaac ctggccgggc tcgacgaccg cctcaacggg gaccaccgct
    17761 tcggactcga cgccgtcggc cgggtgacga gcgtcaccgc ccccggttgg gcggagtcct
    17821 acgcctacga ctccctcggc aacctcaccc acggcacgtg gcccacgggc aacggccacg
    17881 acgcggccct cggcgaacgg acctacaccg ccaccaccct caccgccgca ggcacctacc
    17941 gcttccggca cgacgccgcc ggacgcctgg tcacgcgcac ccgcaagcgg ctgtccaagt
    18001 cccccgagac ctggcacttc gcgtacgacg cggaagaccg tctcaccggc gcccgcaccc
    18061 ccgacggcgt ccggtgggcc taccgctacg acccgctcgg ccgccgcacc gccaagcaga
    18121 agttcaccgc cgacggccgg ggcgtcgccg aggagaccgt cttcacctgg gacggccccg
    18181 tcctcatcga gcagaccagc accggcggcc cgttcccgca gccggtcacc ctcacgtgga
    18241 accaccaggg gctcgtcccg atcacccaga ccgagcgcat cacggacgcc accacccagg
    18301 acgagatcga cgcccgcttc ttcgccatcg tcacggacct cgtcggcaca ccccgcgaac
    18361 tcctcacccc cgagggcgac atcgcctggc gcacgcacac cacgctctgg ggcaccctct
    18421 cctggccgtc cggctccacc gcgcacaccc cgctgcgctt ccccggccag tacgccgacc
    18481 ccgagaccag cctgcactac aacctcttcc gctactacga ccccgccaac gcccggtaca
    18541 cgacccccga cccgctcggc ctcgcgcccg ctccgaaccc ggtcgcgtac gtccacaacc
    18601 cacacacctg gaccgacccc tacgggctcg ccccgtacat ccatgcctcc gtggccagca
    18661 gcgactgggg gaacaagggc gcacacgtcc acatcgggag ccgggaggtc cgggtgttcc
    18721 ccgacggcgc cggcggggtc ggcggcgagc cgatcaggct gtcgaacgga aacgtggcgt
    18781 ctccgcgtga cgtggagcgg gtcctggagg agatccgggt caatccgaaa atgcgcgagg
    18841 acctcatcgc caaggcgtcg tccgcgcgcg cgtccatgaa tgcgggtgag tacggtacga
    18901 aggtgaaccg ggccctcgaa attcacttcc tgatcaaggc gctggagaag atgtgacggc
    18961 gacggacctc gacctgtaca gccgggtcgt gcggcacgag accctcgggg ggcgaccgcg
    19021 gactccacgc ccgaggtgtg ggaacgcgcg cttcccggcg atcacctgga ggacaggcgc
    19081 aagaagttca tgcgctggga ctacggcctc gtcgaggtct tcttcgcccg ggtggaccgg
    19141 cagtggagcg gttccggctt cacgatccag gtgcaccggc tcgccgaggc gggcgggggg
    19201 ccggtcccgg cgtgcctgcg ggacgcgtac ggcgatttcc gcagcagcgt gcccctcggg
    19261 gagctgaccg attccctggc ggcggcgggc ctgtccctca ccgaggtgga gagctattcc
    19321 gacagggaat tcagccagtt cacgtcaccc agcgggcgcg tcgcggtgta cgtcctcacc
    19381 gatccgcggc ccgatgcgga ctaccgcatc ccccgcgggg gatctggtcg atcacggtgg
    19441 cgcccgcgga ggcgtgagcg gtccgccggc ggcgaatgcc gacaagtcga cctgatcaga
    19501 agtcattggt ctacaccttg tcttggtgca gaccaaggtg attgactgcg ccccgtcaag
    19561 ctccaacgcc ggcgttcgcg ccggtgaccc cccaccagga gagtgatgag gtgctgagga
    19621 aactcggaac gaaggtcaag gccatgctcg cgatcggggc gctggccgcc gcgctcgccg
    19681 tcgtggtgcc cgtgaccgcg tcggcaggcg agggcggcac ggcgggcgaa ggaggcgcgg
    19741 acaaggcggt ggccgcggag ttcattgtca gcgaggcgca gttcgagcag atgttcccgg
    19801 ggcggaacgc cttctacacg taccaggggc tgaccgacgc gctcagcgcg taccccgcgt
    19861 tcgccaacac cggtgacgag accaccaaga agcgggaggc cgccgccttc ctggcgaacg
    19921 tcagccatga gaccggcggg ctcgtgcacg tcgtcgagca gaaccaggac aactacccgc
    19981 actactgcga cgcgtcgcag ccctacggct gtcccgccgg gcaggccgcg tactacgggc
    20041 gcgggcccat ccagctcagc tggaacttca actacaaggc cgccggcgac gccctcggca
    20101 tcgacctgct gaacgacccc tggcaggtgg agcggaacgc cgccgtcgcg tggaagaccg
    20161 gcatctggta ctggatgacg cagtccgggc ccgggtcgat gcccgcgcac gacgcgatca
    20221 ccggcgggca cgggttcggc gagaccatcc gggccatcaa cgggtcgctg gagtgcaacg
    20281 gcggcaaccc cggccaggtg cagagccgga tcgacaagta cacgcagttc gtgcagatcc
    20341 tcggcacgac ccccggcgac aacctgagct gctgacccgg ccgggcccga ccggcccggt
    20401 ccgaccgatc ccggccgggt gcgcggcccg gtcccgccct tcccgggtgg gtcgcgcgcc
    20461 cggccgttcc ccccacgtaa ccacccccca cccggaggca gttgtggcac gcgcacgtac
    20521 acacaagttc cggaagacac gcaaacgcct cgtcggcgcc ctcgccgccg cgtcgctcac
    20581 cgccggcgcg ctcgccgccg cggtcgccac cgaggccgcc gccgaccccg agccggtcac
    20641 ccacggcgcc gccgcggtgc ccgcgcacgc cgtcaccggc tactggcaga acttcgacaa
    20701 cggcgccacc gtccagaccc tcgccgacgt ccccgaggcg tacgacatca tcgccgtcgc
    20761 cttcgccgac gcgaccggta cgcccggcca ggtcgacttc accgtcgatc ccgcgctcga
    20821 ctacaccgag gacgccttca aggcggacgt cgccgcgaag caggagagcg gcaagtcggt
    20881 cgtgatcagc gtcggcggcg agcgcggcgc ggtctcggtc aacgacgagg caagcgcgga
    20941 ggcgttcgcc acgagcatcc tcgggctcat ggaggagtac gggttcgacg gcgtcgacat
    21001 cgacctggag aacgggctcg actcgacgta catgacgcag gccctgaagg cgatccacgc
    21061 gggcgccggc gacggcctgg tggtgacgat ggcgccgcag accatcgaca tgcagtcgcc
    21121 ggagaacgag tacttcaaga cggcgctgaa catcaaggac ttcctcaccg tcgtcaacat
    21181 gcagtactac aacagcggtt ccatgctggg ctgcgacggg aaggtctact cgcagggcac
    21241 ggtcgacttc ctcaccgccc tggcctgcat ccagttggag aacgggctcg ccccctcgca
    21301 ggtcggcctc ggcacccccg cctcgtcgcg ggcggcgggc ggcgggtacg tggagccggg
    21361 cgtggtgacc gacgcgctcg actgcctcac gcggggcacc ggctgcggct ccttcaagcc
    21421 ggagaagacg tacccggagc tgcgcggtgc gatgacctgg tccaccaact gggacgccgc
    21481 cgacggcaac gcctggtcgg acacggtcgg gccgcacgtc gaccaactgc cgtaaccgta
    21541 cgggagcaga cagcggggcc ggccgggact tcccgtcccg gccggccccg cccccgtaac
    21601 tcccggtcct cagtcccgtc cgctccgggc cggggtgccg ttctccgccc ccggccagcc
    21661 gttgatcacg aactgcgacc ccggctcgac gaccacgtcg ccctccgcgg agccggtgat
    21721 ggtgacgttc gtgaggttcg cgctgccgcg ggcgccgccc atcgcgagga tgccggcgcc
    21781 gttgttcgac ttctcgatcg acacgttgga gatgttcacg ttcggcatct cgccgccgcc
    21841 cgtcttgaac tggatcccgt cgtacgtcga gtcgtggatg tccgtgtcct tgatcgtcac
    21901 gcccgggatc ggctggcccg cggggaagag cgtgatcgcg ccgaactcct gcgcctcgcc
    21961 ccagaacgcg ccgccgcagc ggtggagcga gttgcccgag atcaccgtct cgccggtgaa
    22021 cggcaccggg tcgtggtcgg tggcgagcat gatgcccggg tagttcgcgg tgtcggagat
    22081 caggttgttc tcgacggtgt tgccgtagcc gccgtagatc gcgaccccgt tcgcgcgcca
    22141 gggcaactgg atggtgttgt tgcggaagtg gttgtcgtgg ccgatgtcga cggcctggtc
    22201 cttca
//
