LOCUS       NZ_RHGC01000008        15496 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Streptomyces alboflavus strain 313 contig008, whole genome shotgun
            sequence.
ACCESSION   NZ_RHGC01000008
VERSION     NZ_RHGC01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces alboflavus
  ORGANISM  Streptomyces alboflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 541582)
  AUTHORS   Guo,Z., Li,P., Chen,G., Li,C., Cao,Z., Zhang,Y., Ren,J., Xiang,H.,
            Lin,S., Ju,J. and Chen,Y.
  TITLE     Design and Biosynthesis of Dimeric Alboflavusins with Biaryl
            Linkages via Regiospecific C-C Bond Coupling
  JOURNAL   J Am Chem Soc 140 (51), 18009-18015 (2018)
   PUBMED   30516971
REFERENCE   2  (bases 1 to 541582)
  AUTHORS   Guo,Z., Li,P. and Chen,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-OCT-2018) State Key Laboratory of Microbial Resources,
            The institute of Microbiology, Chinese Academy of Sciences, No. 1
            Beichen West Road, Beijing 100101, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 10x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003935055.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 13:06:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,631
            CDSs (total)                      :: 7,558
            Genes (coding)                    :: 7,426
            CDSs (with protein)               :: 7,426
            Genes (RNA)                       :: 73
            rRNAs                             :: 2, 3, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 40 of 132
            Pseudo Genes (incomplete)         :: 103 of 132
            Pseudo Genes (internal stop)      :: 12 of 132
            Pseudo Genes (multiple problems)  :: 20 of 132
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:58:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 461694
            Orig. end                         :: 477190
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RHGC01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..15496
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="3"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     cand_cluster    1..15496
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..15496
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:10496](-)"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..10496)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     gene            complement(1225..1683)
                     /locus_tag="EJ355_RS32760"
     CDS             complement(1225..1683)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ355_RS32760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_125264469.1"
                     /transl_table=11
                     /translation="MPKLISSGEVPVDVDFYGLYLQDWDDSQVPVPFPKEWEAGPFVHA
                     RPGRLDFTSGGHTHTAALTVEVWDSEPPTPSGVWEESALTEITSASGQLEVGGVAGGPM
                     PDPIYLSDQARTWTVRVCSAGRAEVAEKARHGVVQGVERYVFQFWPRT"
     gene            1967..2440
                     /locus_tag="EJ355_RS32765"
     CDS             1967..2440
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642396.1"
                     /locus_tag="EJ355_RS32765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Haze protective factor 1"
                     /protein_id="WP_240045090.1"
                     /transl_table=11
                     /translation="MAAERCVSAIAHLYRGIFAIDQMRRPSETERPDCWDLEIDFARAV
                     TVGDGTAVFNSDAPSHDVEVTLRCASQPPPLGGEFVELGEWPFVSYSGDLVFSTTDGPE
                     PELCTRLLEADREYRLRVWAKGRDTAREAFERLQGEVFPITGLEEYVILFETT"
     gene            2717..2998
                     /locus_tag="EJ355_RS32770"
     CDS             2717..2998
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ355_RS32770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_125264470.1"
                     /transl_table=11
                     /translation="MLAGQLRSDDLLQLDGVDHLPDLAGLERLLGADYAFRVPSDSALE
                     FRFRGTASGFLFGVCKEEGLRGELHGRWRAWHCFDNRPFDVQLWVKYR"
     gene            complement(3729..4955)
                     /locus_tag="EJ355_RS32775"
     CDS             complement(3729..4955)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037860.4"
                     /locus_tag="EJ355_RS32775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_125264471.1"
                     /transl_table=11
                     /translation="MKPDAVLLLFSGSKPRHTALLGDAVRAVHDAGLKAVCVAPGDAPR
                     AEGPDTWALYEPGPDRASRALDATAESMSAFHPVRVIPLFEDDVMLAALLRERLGIPGL
                     TVEQSILFRDKNAMNVRAAELGVRTATWSLPHTKSHVRAFAASHEYPIVIKPYDGVSCT
                     DTFKVSSDQELTSTWPLVQAQRHDYRIEAFVHGRQFHVDTLLRDGEILFESVGEYTAQI
                     LESLKNSPMGSVTHPAQGVFRTMLDTTRHIVTSFGLHTGIAHTEFYLGDDGSITFGETA
                     ARMAGAWVPSMYEHALGIRLGYDSVRTEIDTEYRPSATASDCAGASYLWSSAQGTIEHI
                     THPGAVAQLPFVRHVEIWKSPGDHLSEVVGTRGQDLGHVVVTGASADEVRTNLRKVHEL
                     FSVQTANRT"
     gene            complement(5001..6113)
                     /locus_tag="EJ355_RS32780"
     CDS             complement(5001..6113)
                     /EC_number="1.1.1.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Fe-ADH"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012678.4"
                     /locus_tag="EJ355_RS32780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="WP_205048962.1"
                     /sec_met_domain="Fe-ADH (E-value: 4.8e-88, bitscore: 290.3,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVPTGLTFGRGRLNELGRITARHGHTALIVTGRSAMRRTGTLDR
                     AFEALQAAGVKPVVFEGVSPNPRSDEADAAIALARRSGCDVVIGLGGASALDAAKGVAV
                     GFPHASVADLIGKTLEHHPDTLPMIAVPTTTGTGAEVTRGAILVDVRRSFRSGIRGDDV
                     FPKHAVVDPDLSAGLPGRVAVESAFDSMAHAVEGYLARKANPVTDLLCEKVIRTVGEHI
                     TSVADGTADEAAHAALCLAGLLGGMSVANASTCLPHRMQQAMGVRAEGGTPPHARGLAI
                     LYPAWVELVQDAVPERSARIASWVASADLTSYFGQLLPRIGMATSLGDWGYAQQDIPRF
                     MADISGNTDNDPLGQLGDDIVRTIFEKSLA"
     gene            complement(6122..7309)
                     /gene="pgk"
                     /locus_tag="EJ355_RS32785"
     CDS             complement(6122..7309)
                     /GO_function="GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgk"
                     /inference="COORDINATES: protein motif:HMM:NF012389.4"
                     /locus_tag="EJ355_RS32785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_125264473.1"
                     /transl_table=11
                     /translation="MLTLPLLWQTPIRPGDRWVYSAGFNVGKSLGETSRIDSELDDIAY
                     ASGRGAAVALLSHQGSYRDGSAVPLPHIAAYLTRRLGTEVKYFPDTASEEAHQHSRAMR
                     PGDITLFGNTRLYEGEEENDPDLARRFAALGDRVAVGGFSKAHRAHASNTGILAHLPGV
                     LAGSLVSEAETLDPWSGRKETTYSVAVLGGVKPEKTLIGLEHLTGIYDVVIPAGAVLNN
                     ILAALGHSIGVSCLGAKPDVTMAAAARIMARANRAEIPVPEQVVVARPGPEGHADHRAV
                     VVRDGIPDGHAIVDIVLPDRVLGLLEHLVRSKGRALLAGTPSLYSAGHTQAADPLLAAF
                     ETPGVNAMLLGGDTVGELPFQGRTSTGGGSALHYLATGTFPVLKALAQQQARTNP"
     gene            complement(7322..8419)
                     /gene="argC"
                     /locus_tag="EJ355_RS32790"
     CDS             complement(7322..8419)
                     /EC_number="1.2.1.38"
                     /GO_function="GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01850.1"
                     /locus_tag="EJ355_RS32790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="WP_125264474.1"
                     /transl_table=11
                     /translation="MNQGINAGIVGGTGYAGGELCRLLLNHPGVDSILPTARGREEFER
                     VHPNLLGSGLRFISVEELQRRQDELDVVFFCTPSGEAMKGARQFVEAGARVVDVSADFR
                     FRDPEVYRAVYGRDHADPELLQEAAYGITELHRDEVRTARLVANPGCYVITATLGLAPL
                     FRAGYAHAAAPVHISAVNGTTGAGTTPKREILHAKVLNSMLPYSLEGHRHSPELEERLS
                     SLAGHDVTVDFSTAHGNFARGIYAHCSVMVPEELRDKVDRDALLSLYTDYYGSGRAGEP
                     FVVVNEFPKTGQLNEKQYDIYPSLAGVMGSNFCHIGLDYDARRGIIKVIAVTDNIVKGA
                     AGSAIQNMNVMLGLPEHMALSHFGL"
     gene            complement(8455..9438)
                     /locus_tag="EJ355_RS32795"
     CDS             complement(8455..9438)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012607.4"
                     /locus_tag="EJ355_RS32795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="WP_161990388.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 8e-55, bitscore:
                     179.9, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVMDESVEDQARQRRLLILDPFEAATARALADDFDVTERVQPPQ
                     DELLTLVRDADAIVVRSGVRITAEVLNAAPKLRIIARAGVGVDNIDLATARANGVTVFN
                     VPGGSANAVAELALGLMFSAARNIALADGQVRRNIWRKAELGGTELTDKVLGLVGLGAI
                     GSRIATLCRAIGMSVVATVGSRTPERVATWSERGVDIVDSLDEVLDRADFLCLAVPLTE
                     RTRSLLSATELVRMKPSAYLVNVSRGGVVDEDALLDALKNGEISGAATDVLKNEKHPTP
                     LSELDNIVLTPHIGAMTHETQARIGAIVAENIRAAFAGRHVENRVC"
     gene            complement(9633..10496)
                     /locus_tag="EJ355_RS32800"
     CDS             complement(9633..10496)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075322.1"
                     /locus_tag="EJ355_RS32800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_125264476.1"
                     /sec_met_domain="phosphonates-like (E-value: 3.7e-119,
                     bitscore: 391.7, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.8e-103, bitscore:
                     340.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.1e-64, bitscore:
                     213.1, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQRPTGPTFRQTVERTELVRVAGAHDALGGVLAQQAGFNAVWSSS
                     LEVSAARCLPDASVLSMTEYLEAAANMQKALSIPVIADCDTGYGNNLNVTHMVHEYEAA
                     GITAVCMEDKLFPKLNSFAAGDQTLLSTEEFCGKIRAAKNAQADDDFYVVARTEALING
                     LGVEEGLTRAYAYAEAGADAVLIHSKSKTKDEVEGFLAQWDGRRPVVIVPTTYPEWHVD
                     DITKAGVSVVIYANQGLRATVSSLRTTFEAIQKHGDTTHLEENIASVKDVFALQRLAEW
                     QALESV"
     gene            complement(10518..11687)
                     /locus_tag="EJ355_RS32805"
     CDS             complement(10518..11687)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="EJ355_RS32805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_161990389.1"
                     /transl_table=11
                     /translation="MTLVQSAGSGLFLTSNAIFLTRYAGLSPFQVGLGLAVAGFFGFAA
                     TVPLGRLADRTGAQPLLFAGYGALAVLFVAYCFVGTFAAFVVVASLISICETSASPLRA
                     ALLQSLFSGPLVVRVRAQMRSAFNLGYMLGAAASGGALAVGSVSAFFTVLIVNAAAQAA
                     CVVMTVRLKPTSVVTHKKRGERRRHGGALRDRPFLALTAVNGFLELHYTVFTVGIPLWI
                     VSHTDAPSTLNSVLLITGTVLVIVLQLPMSRNVDTLETAATVMRRGGFFMAVSCALFAA
                     SGVGGNGVAISFMLIATVLLAIGEVAQSAGSWGISFGWPPADRQGEYQSVYGLGRGIRE
                     FVGPALMASLIVPFGWKGWIALGGIFFALSFLPVPLVRAGRPAQAAEIH"
     misc_feature    complement(11877..11889)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     misc_feature    11932..11949
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.7"
                     /tool="antismash"
     misc_feature    complement(11934..11949)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            12019..12672
                     /locus_tag="EJ355_RS32810"
     CDS             12019..12672
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358791.1"
                     /locus_tag="EJ355_RS32810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF402 domain-containing protein"
                     /protein_id="WP_125264478.1"
                     /transl_table=11
                     /translation="MTERFSPGQVIVRRELLDGRPWITYPVRVVEDGDELLALYMAKGT
                     PMTFGSGPFSWGPHPWQAIADTWQSPGVLQLQRPGELYAVWVFWSEDRSRHDWYVNFQR
                     PFRRTTHGIDTLDLELDIWVPGDGSPYRWKDVDHFESRAEAGGFADGEDRRVREAARAL
                     TLGLDRGETWWDPAWSRWRPETAWTVPERVPHAVAESARPAEAGVEAAPLSAPV"
     misc_feature    complement(12854..12863)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            12999..13370
                     /locus_tag="EJ355_RS32815"
     CDS             12999..13370
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765035.1"
                     /locus_tag="EJ355_RS32815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_125264479.1"
                     /transl_table=11
                     /translation="MTFLAVVEGDAGGWRIDQDVLAAAIRARWGEVEIDSTHRSEVRSI
                     IWTFVTEAGPGEAYLHADGICLYMNVWEEDAIWLAIALRGLMPTDLDLVFCDEGYTFDV
                     RLPTGTTEAELAAWVHATG"
     gene            complement(13373..>13506)
                     /locus_tag="EJ355_RS32820"
                     /pseudo=""
     CDS             complement(13373..>13506)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988951.1"
                     /locus_tag="EJ355_RS32820"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="IRALGEQAMAPLKQWRLLRKLRCTNTRITGIVKPSWSSTSPP"
     gene            complement(13609..14226)
                     /locus_tag="EJ355_RS32825"
     CDS             complement(13609..14226)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075790.1"
                     /locus_tag="EJ355_RS32825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_240045109.1"
                     /transl_table=11
                     /translation="MLVPTTVAHAADPGEDVTLPVRDALATLTVADESREGYERTKFKH
                     WVDADRDGCHTRSEVLLEEAVTPPEQGARCTLTGGRWYSPYDDRYIEGPRTIDIDHYVP
                     LAESWDSGASAWTPAEREAYANDLDDKRSLIAVTATSNRSKADQDPATWMPPAAGYHCA
                     YATTWVTVKTRWKLAIDPAEATALTSTLNECPNTPIEVELAR"
     misc_feature    14481..14492
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.1"
                     /tool="antismash"
     gene            complement(14523..14681)
                     /locus_tag="EJ355_RS38700"
     CDS             complement(14523..14681)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EJ355_RS38700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_161990390.1"
                     /transl_table=11
                     /translation="MATSMLRTVAAHDTNSTRAAGKEWLLAHSYDALVDELQEIVDVEA
                     GLGETVL"
ORIGIN
        1 cggtggggcc ggcgcgcggc gcgttcaccc gagcggggca ggattcggcg atggctgtgc
       61 cggagcggga cctgtcgtcg gtgcgcggga gggcggggtc ggccgcggtc ggtttgccgg
      121 agcctgcgca cacgatgacc acgcagcagt gcgtcaaggg actggcgaac aagaagttct
      181 atatccgttc ccggttcgcg gtgtgttcgg gccagacctt caagcaggtg tggctgaggg
      241 gggcttcacc ggtcggggcg agttccttca cggcactggc gatcgggacg atcccgaaga
      301 acagccgcac gatgaccgtc accttccgat tcaccaattt cgtggcgaca ggtgtgcaca
      361 acgctcccgg gatcaccatc gccaccaggg cgaagatcgc caagagctgg ccgtcccgcg
      421 tgcggtacaa gcacggaggg gcaggcacgg ccatgccggt gaaacggaag tgggctcagc
      481 tgctgaacgg agggggcttc aagcacacgg tgtcggctgc cgcagggcag ggccacgcgg
      541 ggacggatga cagcatctac gccgtttacc agcccaatat caaggcgacg gccccgccgg
      601 actggtctga ggtgaagccg agcggcggcg acttgttcat gctgccgccg cgctgggaca
      661 aggctgccta ccttcccaac cgcaccaagg gcgcggcggc cttcagcgtg tcgacggccc
      721 tcgtctacag caccaagagc acggcaccgg agaaggatgt ggccaaacac atcaaactgg
      781 cgtacaccaa cccgggccgg acgcagcctc ctttcagcgg caagcgcctg gcggggaaca
      841 aggcggatga gcctttgacg cgcttgtaca aggacatggc tcggcggaag gagaaccgga
      901 ataccgctgt ctacaactgc cggaagtact ttggcgacga ctacgcagag ggaggacaga
      961 aagagtgcga tgagttcccg ttcgcgacca cctatcaagg ggcggcggaa tggaagcaca
     1021 accagcaggc cgaccgctac aacttcagcg tcaaagccct gcccgcgaag tcaaacggtg
     1081 cggccggaac actgctccgt gactattaca atatgaaccg gatgattgac ggcccggatg
     1141 acggattcct catgaagatc acctcctgag gagcccctgt cggccggggc cagacggtga
     1201 tccgcctggc cccggccgac tgactcaggt gcgtggccag aactggaaga cgtagcgctc
     1261 cacgccctgg acgacgccgt gccgggcttt ttctgccacc tctgcccggc ccgcactgca
     1321 cacgcgaacg gtccacgtgc gggcctggtc cgagaggtag atggggtcgg gcatcggccc
     1381 gccggcgact ccgccgacct caagctgccc agaggcagag gtgatctcgg tcagcgcgga
     1441 ctcctcccag acgcccgacg gcgttggcgg ctccgagtcc cacacctcga ctgtcagtgc
     1501 tgcggtatgg gtgtgcccgc cgctggtgaa gtccaggcgg ccgggccgcg cgtgcacgaa
     1561 cggccctgcc tcccattcct tggggaaagg gaccggtacc tggctgtcgt cccagtcctg
     1621 caggtagagg ccgtagaagt cgacgtcgac gggtacttct ccggagctga tcagcttggg
     1681 catgttttcc cctctcccca tcacgcggtc tcggtcaaca tatcggcagg cgccatgacc
     1741 gtgggacagc tccatggtgc gtaccggtac cagtcagcgg gcagagggtc ggactgggag
     1801 cgtgccacgc accacgcgcc tacggggtat gcgaaggcgc tgttgggctg cgcgcctcgt
     1861 ggcggctgtg atgcggtgaa ggggcgcgct gggcggtccg ctgcggagcg cgccgggggt
     1921 tgcaggaggc tgggcagtcc ggtgcaggca gaggaaagga aacggcatgg cagccgaacg
     1981 ctgtgtctcg gcaattgccc atctttacag agggattttc gcgatcgatc agatgcgcag
     2041 gccgtcggag acggaacgcc ctgactgctg ggatctggag atcgacttcg cgcgtgctgt
     2101 cacggtcggg gatggcacgg cggtgttcaa cagcgacgcc ccgtcccacg acgtcgaggt
     2161 gaccctgcgg tgcgccagcc aacctccgcc cctcggcggg gagttcgtcg agctggggga
     2221 gtggcccttc gtcagttaca gcggtgatct cgtgttttcc acgaccgacg ggcccgagcc
     2281 ggagttgtgt acgcgacttc tggaggcgga ccgcgagtac cgcctgcggg tgtgggcgaa
     2341 gggcagggac acggcacggg aggcgtttga gcgcctgcag ggggaggtgt tccccatcac
     2401 cggcctggag gagtacgtca tcctcttcga gaccacctga ccgtgcgcct gtccgcgccc
     2461 ggctagggga gcggtctcca aggcgtgggg caagccttgg aggccggggc gctgacagcg
     2521 ggcagggccg gggtgagcgg gacgggcgcg cccgcgtgct gccgttgtgg tcagtcgatg
     2581 tagatgccgt acgggtctcc gtcgagggcg cggtccttgc cgtaccacag gacgagaggg
     2641 agggggcaca gcggagaccg gctggagggc gcgagtaaga gatcaactca tgtggcgatg
     2701 ccggtagtct gcctgcgtgt tggcaggtca acttcgcagt gatgacctgc tgcagctaga
     2761 tggagtcgac cacctgcccg acttggctgg ccttgaacga ctactggggg ccgactacgc
     2821 cttccgagtt ccttcggaca gtgcccttga gttccgtttc cgggggactg ccagcgggtt
     2881 cctcttcggc gtctgcaagg aagaaggact caggggagaa ctccacggcc ggtggcgggc
     2941 ctggcactgc ttcgacaacc ggcccttcga cgtgcagctc tgggtgaagt accggtgacc
     3001 aagaactcgg gtacgcctcg gtaactgcca gcggctggat ccggtcagtc gacgtgcacc
     3061 gtgatgctga tccaccgcct ggtggctggt ggatcagcat cctcatgatg tctccgggag
     3121 cggcggacgg gctgtgggtg ccgtctgacg ggtgtggtgc ggccagccac cgcttcgccg
     3181 actggtaccc cagggacgga cgtccgggcc tctcgcctgc tcaacagccg tggaagcacc
     3241 cacgccccgc cagccgactg cctttccaga accctcgacc aacgcgagat tcctcgactg
     3301 aagttctggc gcaccctggg tagttgacct cgacggctac aagatccccg acggagtcaa
     3361 ctacttacgc cgtgctgctc atttgatgcg gccgatcagg gccccgcgca ctggctcgtg
     3421 tcgcgcagcc gacgtgccca gttgctgtac gcagtgctgg tgcaggtgga tgctcagcac
     3481 acggcgcctg ccgaagatga aggtacgggc ccaggttcgc catctcgagc gaagctcgcc
     3541 atttcactga gaccgggcac cctcctttct ggctcccgtc cgcaggtcag ccaacagcaa
     3601 ggccgtggcg gccgatccag ggttcgcaca tcgcgtgagc gacgggtgaa gacgcccgtg
     3661 acgggccaac ctgaccgccc gtctctccgt cttctctcac ctctgttcca cacagagacg
     3721 accactgctc aggtgcggtt cgcagtctgt acggagaaca gctcgtgcac cttccggaga
     3781 ttggttcgaa cctcgtcggc tgaggcgccg gtgacgacca cgtgtcccag gtcctgcccg
     3841 cgggtgccga cgacttcgga caggtggtcg ccgggcgact tccagatctc gacatgacgg
     3901 acgaacggca gctgcgctac ggccccgggg tgcgtgatgt gctcgatcgt gccctgcgcg
     3961 gagctccaca ggtaggaggc tcctgcgcag tcggacgctg tagccgacgg gcggtactca
     4021 gtgtcgatct ctgtccgtac ggagtcgtat cccagtcgta tcccgagggc gtgttcgtac
     4081 atggacggca cccaggcgcc cgccatgcgc gcggccgtct ccccgaaggt gatgcttccg
     4141 tcgtccccga ggtagaactc ggtgtgcgcg atgcctgtgt gcagcccgaa cgacgtcacg
     4201 atgtgccgtg tggtgtccag catggtccgg aagaccccct gcgccggatg ggtcacgctg
     4261 cccatcggag agttcttcag gctctcgagg atctgcgcgg tgtattcacc caccgattcg
     4321 aagaggatct cgccgtcgcg caggagcgtg tcgacgtgga actgccggcc gtgcacgaac
     4381 gcctcgatcc ggtagtcgtg gcgctgtgcc tgtacgagtg gccaggtcga ggtcagctcc
     4441 tggtcagagg agaccttgaa ggtgtccgtg catgaaacgc cgtcgtaggg cttgatgacg
     4501 atggggtact cgtgtgaggc cgcgaaggcg cgcacgtggg acttggtgtg gggcagtgac
     4561 caggttgctg tccgcactcc cagctccgcc gcgcgcacat tcatggcgtt tttgtcccgg
     4621 aagaggatgc tctgctccac ggtcagacca ggtatgccga gtctctcgcg cagcaaggcg
     4681 gcgagcatga cgtcgtcctc gaagagcggg atcacccgca ccgggtggaa ggcgctcatc
     4741 gattcggctg tggcgtccag ggcccgggat gcacggtcgg ggcctggttc gtagagcgcc
     4801 caggtgtcgg ggccctcggc tcggggcgcg tcgccgggag cgacacagac tgccttgagc
     4861 cctgcgtcgt gcaccgcgcg taccgcgtcc ccgaggagtg cggtgtgccg cggtttgctg
     4921 ccggagaaga ggaggagtac ggcgtcgggc ttcatctgga tgacccttct cgcgtgtcgt
     4981 gatcttcggt acgggcgcgg ctacgcaagg gacttctcga agatggtccg cacaatgtcg
     5041 tcaccgagct gcccgagcgg gtcgttgtcg gtgtttccgc tgatgtcggc catgaaccgg
     5101 gggatgtcct gctgtgcgta tccccagtcg cctagggacg tcgccatacc gatccggggc
     5161 agcagttgcc cgaagtagct ggtgagatcg gcgctcgcga cccatgaggc gattcgtgcg
     5221 ctccgctcgg gcacagcgtc ctgtacgagc tcaacccagg ccgggtacag aatggccagc
     5281 cctcgggcgt gcgggggtgt gccaccctcg gcgcgcactc ccatggcctg ttgcatgcgg
     5341 tgcggcaggc aagtgctggc gttggccacg ctcatgccgc cgagcagacc tgccaggcac
     5401 agggctgcat gcgcggcctc gtccgccgtg ccgtcggcca cggaggtgat gtgctcgccg
     5461 accgtgcgga tgaccttctc gcacagcagg tcggtgaccg ggttggcttt ccgcgcgagg
     5521 tagccctcga ccgcgtgagc catactgtcg aacgccgact ccaccgccac tcgtccgggc
     5581 agaccggcgg agaggtcggg atccacgacg gcgtgcttcg ggaacacgtc gtcccctcgg
     5641 atgccggagc ggaagctgcg gcgcacgtcc acgagaatcg cgccgcgcgt cacctcggca
     5701 ccggtgcccg tagtggtggg tacggcgatc atcggcaggg tgtccggatg gtgttccagg
     5761 gtcttcccga tgaggtcggc gacgctcgcg tgcgggaatc cgaccgccac gcctttcgcg
     5821 gcgtccagcg cgctcgcgcc accgagaccg atcaccacgt cacagcccga gcggcgggcg
     5881 agggcgatgg cggcgtcggc ttcgtccgac cgtgggttgg gggagacgcc ctcgaagacg
     5941 acgggcttca ctccggccgc ctgcagcgcc tcgaaggcgc gatccagtgt gccggtcctg
     6001 cgcatggcgg agcgcccggt gacgatgagc gccgtgtgac cgtggcgggc ggtgatccgt
     6061 cccagctcgt tcagacggcc tctgccgaag gtgaggccgg ttgggacctg catgtcgaac
     6121 atcatggatt cgtcctcgct tgctgctggg caagtgcctt cagcacggga aaggtgcctg
     6181 tcgccaggta gtgaagtgcg gaaccgccgc cggtggacgt ccggccctgg aaggggagtt
     6241 cgcccacagt gtcgccgcca aggagcatgg cgttcacccc gggcgtttcg aacgccgcca
     6301 ggaggggatc ggccgcctgc gtgtgtcctg ccgagtagag ggaaggcgtg ccagccagga
     6361 gcgcgcggcc cttggacctg acgaggtgtt caaggaggcc gagcacccga tcgggcagga
     6421 cgatgtccac gatggcatgt ccgtcgggga tgccatcgcg cacgacaacg gctctgtggt
     6481 ccgcgtgccc ctcgggcccg gggcgtgcga caacgacctg ctcgggaacg gggatctcgg
     6541 cccggttggc gcgtgccatg atgcgcgcgg ccgccgccat cgtgacgtcg ggcttcgcac
     6601 cgaggcagga cacgccgatg gagtgcccca gggcggcgag gatgttgttc agtacggcac
     6661 cggccgggat gacaacgtcg tagatcccgg tgaggtgttc cagaccgatc agggtctttt
     6721 ccggcttcac accacccagg acggcgacgg agtacgtcgt ctctttgcgg ccggaccacg
     6781 gatccagcgt ctccgcctcc gagaccaggc ttccggcgag aacgcccggc aggtgggcga
     6841 ggataccggt gttggaggcg tgtgcccggt gcgccttgga gaaaccgccg acggccaccc
     6901 ggtcccccag ggcggcgaag cggcgcgcca gatccggatc gttctcttct tcgccctcgt
     6961 acagcctcgt gttgccgaag agcgtgatgt ctccggggcg catcgcccgg ctgtgctgat
     7021 gcgcctcctc ggaggctgtg tcagggaagt acttgacctc ggtgcccagc cggcgggtca
     7081 ggtacgcggc gatgtgtggc agcggaacgg cgcttccgtc ccggtacgag ccctggtggg
     7141 agaggagagc gactgcggcg ccgcgcccgg aggcgtaggc gatgtcgtcg agttcgctgt
     7201 cgatgcggga ggtctcgccc aacgacttgc cgacgttgaa tcccgcggag tagacccagc
     7261 ggtcaccggg tcggatgggt gtctgccaca gcagcggaag tgtcaacacc tgctctcccg
     7321 ctcagagtcc gaagtgggag agagccatgt gctcgggcag gcccagcatg acgttcatgt
     7381 tctggatcgc cgagcccgcc gcgcccttga cgatgttgtc cgtgacggcg atgaccttga
     7441 tgatcccgcg ccgggcgtcg tagtcgaggc cgatgtggca gaagttggag cccatgacac
     7501 ccgccaacga cgggtagatg tcgtactgct tctcgttcag ctgtccggtc ttggggaact
     7561 cgttcacgac gacgaacggt tcgccggcgc ggccgctgcc gtagtagtcc gtgtagagcg
     7621 acagcagtgc gtcgcggtcc accttgtcac gaagttcctc gggcaccatg acgctgcagt
     7681 gggcgtagat cccgcgggcg aagttgccgt gcgcggtgct gaaatcgacg gtgacgtcat
     7741 gacccgccag cgaggacagc cgctcctcca gctcgggact gtgccggtgg ccttccaggc
     7801 tgtacgggag catggagttg aggaccttgg catggaggat ttcccgcttg ggtgtcgtgc
     7861 ctgcccccgt ggtgccgttg acggcactga tgtgcacagg ggccgccgca tgcgcatacc
     7921 ctgcgcggaa gaggggcgcg agtcccaggg tggctgtgat gacatagcac ccaggattgg
     7981 ccaccagccg ggcggtgcgc acttcgtcac gatggagttc ggtgatcccg tacgccgcct
     8041 cctggagcag ctcggggtcg gcgtgatcgc gtccgtagac ggcccggtag acctccgggt
     8101 cacggaagcg gaagtccgcg ctgacgtcga cgacgcgtgc gccggcctcg acgaactgac
     8161 gtgcgccctt catcgcttcg ccggagggag tgcagaagaa gacgacgtcg agttcgtcct
     8221 ggcgcctctg cagctcctcg acgctgatga agcgaagccc gctgcccaag agattggggt
     8281 gtacccgctc gaattcctcg cgaccgcgag cggtcggcag gatgctgtcg acgcccggat
     8341 ggttcagcag gagacggcag agttccccgc cggcgtatcc cgtgccgccg acgatgccag
     8401 cgttgatgcc ctggttcatg gtttctcctt ccctgcccgg atgggccggg cgtctcagca
     8461 gacgcggttc tcgacgtggc ggccggcgaa cgcggccctg atgttttcgg cgacgatcgc
     8521 gccgatacgg gcctgcgtct cgtgcgtcat ggcaccgatg tgcggggtga ggacgatgtt
     8581 gtcgagttcg ctgagaggcg tcgggtgctt ctcgttcttc aggacgtcgg tcgcggcacc
     8641 cgagatctca ccgttcttga gggcgtccag cagtgcgtct tcgtccacga cgccgccccg
     8701 cgagacgttg acgaggtagg cgcttggctt catcctgacc agttcggtgg ccgagaggag
     8761 gctgcgggtc ctctcggtga gcgggacggc gaggcagagg aagtcggcac gatcgaggac
     8821 ctcgtccagg ctgtccacga tgtcgacgcc ccgctcggac cacgtggcga cgcgttccgg
     8881 cgtgcggcta ccgacggttg cgacgacgct catgccgatc gcccggcaga gtgtcgcgat
     8941 gcgggagccg atggcaccca gcccgaccag gccgagcacc ttgtcagtga gctctgtccc
     9001 gccgagctcg gccttgcgcc agatgttgcg gcgcacctgg ccgtccgcga gagcgatgtt
     9061 ccgagcggcc gagaacatca ggccgagggc gagttccgcc actgcgttgg cggatccgcc
     9121 cggcacgttg aagacggtga cgccattcgc ccgtgccgtg gcgaggtcga tgttgtcgac
     9181 acccactccc gcccgcgcga tgatccgcag cttcggtgcg gcgttcaaca cctcggcggt
     9241 aatcctgacg ccgctgcgca ccacgatcgc gtcggcgtcg cggacgagcg tgagcagctc
     9301 gtcctggggc ggctgcacgc gttcggtcac atcgaagtcg tccgcgagag cgcgggcggt
     9361 ggcggcttcg aacgggtcaa ggatcagcag gcgccgctgc ctggcctgat cctccaccga
     9421 ctcatccatc actgacatgc agggttcctc tgggtagggg atcgttccgg gttccctggc
     9481 gtctgcttgc agggggcagg tagtgtcatg gcaacggctt cgcgccgtcg ccacgaatgg
     9541 ccaggacact cgcactgtcc tggccattcg gagtcaccgc ccgcgctgcg cgaggcagac
     9601 cgccgggtcg gggtggctgt tcgggcccgg tctcagacgg actcgagggc ctgccactca
     9661 gccagccgct gaagggcgaa gacgtccttg accgaggcga tgttctcctc gaggtgggtc
     9721 gtgtcgccgt gcttctggat cgcctcgaag gtggtacgga gagaggagac cgtggcccgc
     9781 agtccctgat tggcatagat cacgacggac acgccagcct tggtgatgtc gtcgacatgc
     9841 cactcggggt atgtggtggg gacgatgacc accgggcggc gcccgtccca ctgcgcgagg
     9901 aagccctcga cttcatcctt cgtcttggac ttggagtgaa tgagcaccgc gtccgcgccg
     9961 gcctcggcgt acgcgtacgc tcgcgtgagc ccttcctcga caccaaggcc gttgatcagc
    10021 gcctcggtcc gagccaccac gtagaagtcg tcgtcggcct gcgcgttctt ggccgcgcgg
    10081 atcttcccgc agaactcttc cgtggacagc agtgtctggt cgccggccgc gaagctgttg
    10141 agcttcggga acagcttgtc ctccatgcag acggcggtga tgcccgcggc ctcgtactca
    10201 tgcaccatgt gggtcacgtt gaggttgttg ccgtatcccg tgtcacaatc cgcgatgaca
    10261 gggatgctga gggccttctg catgttggcc gcggcttcca agtactccgt catgctcagc
    10321 acgctggcgt cgggcaggca ccgagccgcc gacacctcca ggctggacga ccagacggcg
    10381 ttgaagccag cctgctgcgc gagaacaccg cccagagcgt catgtgcacc ggcgacgcgt
    10441 accagctcgg tgcgctcgac ggtctgacgg aaggtgggac ccgtgggtcg ttgcattctt
    10501 tctctccatt tcggaaatta atggatctcc gccgcctgtg cgggacgccc cgcacggacg
    10561 agcggcaccg gtagaaagga aagcgcgaag aagatgcctc cgagcgctat ccaccccttc
    10621 cacccgaagg ggacaatgag cgaggccatc aaggccgggc ccacaaattc gcggattccc
    10681 cggcccagtc cgtagacgct ctgatactcg ccctggcgat cggccggtgg ccagccgaac
    10741 gatattcccc agcttcctgc cgactgtgcc acctcgccta tagcgagaag cactgtcgca
    10801 atcagcataa aggaaattgc gactccgttg ccgcccaccc cgctagccgc gaacagtgca
    10861 caggagactg ccataaagaa tccaccgcgc cgcatgacag tagcagcggt ttccaaggtg
    10921 tccacattcc tgctcatcgg caattgaaga acgatgacca gcaccgtccc cgtgatgagc
    10981 aacacggagt tcaacgtcga cggggcgtct gtatgcgaga cgatccacaa gggaatgccc
    11041 acagtgaaaa cggtgtagtg aagttccagg aacccgttga ccgcagtgag cgcgagaaag
    11101 ggcctgtccc ggagcgcgcc tccgtgtcgc cgccgctcgc cacgcttctt gtgagtgacg
    11161 acggaagtgg gcttgagacg gactgtcatc accacgcagg cggcctgggc cgccgcgttg
    11221 acgatcagta cggtgaagaa ggcggagacg ctgccgaccg ccaaggcgcc gccggaggcc
    11281 gcggccccca gcatgtaccc gaggttgaag gcactccgca tctgagcgcg gacccggacc
    11341 acgagcggtc ccgagaagag ggactgcaag agtgcggccc gcagagggct tgccgatgtc
    11401 tcacagatgg atatgagaga ggccacgact acgaaagccg cgaaggttcc gacgaaacaa
    11461 taggccacga acagtaccgc cagagcgccg taacctgcaa aaagcagggg ctgtgcacct
    11521 gttcggtcag ccaagcgtcc cagagggacg gtcgccgcga atccgaaaaa acctgccacg
    11581 gcaagcccga gccccacctg aaaaggagag aggccggcgt accgagtgag gaagatggcg
    11641 ttcgaggtca gaaagagacc actgcccgcc gactgcacca gggtcaataa cactaagcga
    11701 cgtgcatgac ccttgtccgg tatcagatcg gccagccagc gactgaccga aagctttcgt
    11761 tcttttcttt cctgaagcat gaagtgccta gtgcttgcct aacccgcgag agggggtcgc
    11821 ccaaggtggt cgcatcaagg cagaaagatc cgccttcgga ttcgagcaag ggtgtcttgc
    11881 aagatccatt agagaacttt ccatgtgcat gtatctgatg tcaacgggag aatgtgaagg
    11941 aaatgtgaag tgaactttgg atttcaacaa ggtgtacccg gagtgaagga tcgcgcggcg
    12001 atgtgcttct gtacggctat gacagaacgc ttttcccccg ggcaggtcat cgttcgccgc
    12061 gaactgctcg acggcaggcc gtggatcacc tacccggtac gcgtggtgga ggacggtgac
    12121 gagctgttgg cgctgtacat ggcgaagggc actcccatga cgttcggctc tgggccgttc
    12181 tcctgggggc cccacccatg gcaggccatc gcggacactt ggcagtcgcc cggggtcctt
    12241 caactgcagc ggccgggcga gctctacgcg gtctgggtct tctggagcga agaccgttct
    12301 cgccatgact ggtacgtcaa cttccagagg ccgttccgca ggaccacgca cggcatcgac
    12361 accctcgacc tggaactcga catctgggtg cccggcgacg gcagccccta ccggtggaag
    12421 gacgtcgatc actttgagag ccgggcggag gcgggtggct tcgccgacgg cgaggaccgc
    12481 cgggtacgtg aggcggcacg cgcactgacg ctcgggctcg accggggcga gacatggtgg
    12541 gacccggcct ggtcccggtg gcgccccgaa actgcctgga cggtcccgga gagggtgccg
    12601 cacgcggtag ctgagtcggc acgacctgcc gaggccgggg ttgaggcggc cccgctttcg
    12661 gcgccggtgt gagaggacct cccgggcagg ggatccggct cggggcgcgg tgggcatagc
    12721 ctgccccacg cgggtcaacc gccgtcaaag gtccgcgcag agcctatgtg gaccttcgtg
    12781 gtgcacctcg ctcgcgagga agatctccag ttctcgtcac agcggtgagg ccagatgcct
    12841 agctgacgaa ctgggccgcc ttccggcacg tatcggccac gagcccaggc cctgcacggc
    12901 acagctctac tcgccgtgag ccaccaccac tgagcccatt ccaacttcgg cgacggctga
    12961 tcagccgctg tgtcatgggc gtctgataga ccctggccat gacgttcttg gcggtggtcg
    13021 aaggtgatgc gggcggatgg cgcatcgatc aggatgtgct ggcagcggcg atccgtgctc
    13081 ggtggggtga ggttgagatc gactcgacgc accgcagtga agtccgcagc atcatatgga
    13141 cgttcgtgac ggaagccggc ccgggtgagg cgtatctgca cgcggacggc atctgcctgt
    13201 acatgaacgt gtgggaggag gacgcgatct ggttggcgat cgccctccgc ggactgatgc
    13261 ccacggacct tgacctggtc ttctgcgatg agggctacac cttcgacgtg cgcctgccga
    13321 ccgggactac tgaagccgaa ctggcggcct gggtgcatgc tacgggttga tttcagctca
    13381 cggtggcgag gtggaggacc aggacggctt gacgatgccg gtgatgcggg tgttggtgca
    13441 ccggagtttc cgtagcaggc gccactgctt caagggggcc atggcctgct cgcccagcgc
    13501 gcggatggcg cgcggtctgc tccagtccgg gggcacaagt ggagaccggc tgaagggctg
    13561 gggcgcgagt aagcccccgc gccgccaggg cgcgggggct gtgccgttct atcgggcgag
    13621 ttccacttcg atgggggtgt tcgggcattc gttgagtgtg ctggtgagtg cggtggcctc
    13681 ggccgggtcg atggcgagct tccacctggt tttgacggtg acccaggtgg tcgcgtatgc
    13741 gcagtggtag cccgcggccg gtggcatcca ggtggccggg tcctggtccg cctttgaccg
    13801 gttgctggtc gcggtgacgg cgatcaggga gcgcttgtcg tcgaggtcgt tggcgtatgc
    13861 ctcacgctcc gcaggtgtcc aggcggaggc gccggagtcc cagctttcgg cgagtgggac
    13921 gtagtggtcg atgtcgatgg tgcgggggcc ttcgatgtac cggtcgtcgt agggggagta
    13981 ccagcggccg ccggtcaggg tgcagcgtgc tccctgttcg ggtggggtga cggcttcttc
    14041 gaggagtacc tcggagcggg tgtggcagcc gtcgcggtcg gcgtcgaccc agtgcttgaa
    14101 cttggtgcgt tcatagcctt cgcgcgactc gtcggcgacg gtgagcgtgg cgagagcatc
    14161 acggacgggc agggtgacat cctcgccggg gtcggcggcg tgggcgactg tggtggggac
    14221 gagcagggcg gtgagggtgg ccagggtagc ggcggcgcgg aagcgcacga tctcctccga
    14281 agaacgcgac aacaggtcgt gatcttcgta gcgctgcagc gagcaaccag gcagacgatt
    14341 tgctgctgcc tcacccgggc gggcggtaag tcacacttct gggccacggg cagcggttca
    14401 tctgtaagtg acgactgtgg gtctcatgta tcgaggtctg gccgtggccc caggatgtcg
    14461 cggagtccgg cctcggtatc gagaacggtt tcgaggtcgt ggacagggac atcgtgctgg
    14521 ggctacagga ccgtctcgcc gagcccggcc tcaacgtcga cgatctcttg gagctcgtcg
    14581 accagtgcat cgtagctgtg cgcgaggagc cattctttgc ctgctgcccg cgtggagttt
    14641 gtgtcatggg cagccaccgt cctgagcatg ctggtcgcca tctcggttgg atgtggctct
    14701 tcctgagtga gatcgccgat caggccgaga ggctgtcgtt gtgctggtcg ggttgggggt
    14761 ggagcagcac gacgccatcg ccgccccggc ctcgaacctg gacacggcga tccagcagat
    14821 gatccgcggc agcaacagcc caccacgccg atctcactca gggagagcta cggccatctc
    14881 ggttctgacg atgtcgctgt gatccgttgg cttgtcctgt gctcgttgtt gcggccgggc
    14941 aagggagcag ttggtggcgg gggtgcggcc cggtgggcgg gccgcacccg gctttatggc
    15001 gtggcgagct cgcacgagtg caccggcggt tcctcgagcg cgagcgcgtc gtagaagtcg
    15061 atttcttcgg gcggcgcggg ctctgtgacg gcgggcagct cctcctcctg ctcgtgccgg
    15121 gtggcatcgg tgggccaggt aaagagcagc ttcggctcgg ctgccgacag ccggcgcccg
    15181 gcccgtcgca ggcggctctt gaactcgtcc gtcgtgggga tcgggcccgt gctgcgccgt
    15241 cggggggcta agggccggtg gtagcgcggc ccttccagct cggtccggat cacgtcaccg
    15301 gagcgggcat cgggaaggac ttcgcgccct accactcctt cgtgacgaac ggcgatgcgg
    15361 tcgcggtcgc gagtgacccg gtcgtgctgc cgctggggga gaatgccggg gacctcgttg
    15421 aggcccgcgt cctcttgctt ctcaaagcgc caggcgcgac tccaggcgtc ctcccatgcc
    15481 ctgcggtgct cggcgg
//
