MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
WP_030578062.1 cytochrome_P450 BGC0001753.3 ribosomal:RiPP 54.0 96.9 416.0 5.47e-144
CBZ42154.1 putative_P450-like_enzyme BGC0001117.5 NRPS:Type I 52.0 96.6 404.0 3.59e-139
AEP40931.1 cytochrome_P450_monooxygenase BGC0000021.5 PKS 51.0 94.2 384.0 2.67e-131
CBZ42148.1 P450-like_enzyme BGC0001117.5 NRPS:Type I 51.0 97.1 383.0 5.73e-131
WP_004562636.1 cytochrome_P450 BGC0002009.4 PKS 48.0 94.5 355.0 4.33e-120
OWA25229.1 cytochrome_P450 BGC0001438.5 PKS+saccharide:hybrid/tailoring 49.0 95.4 354.0 7.72e-120
ABV56593.1 KtzM BGC0000378.5 NRPS:Type I 47.0 95.4 353.0 3.21e-119
DAC74139.1 cytochrome_P450 BGC0002019.3 terpene 51.0 92.1 347.0 3.61e-117
CBZ42153.1 putative_P450-like_enzyme BGC0001117.5 NRPS:Type I 45.0 95.4 342.0 5.59e-115
ABB69748.1 PlaO3 BGC0000654.4 terpene:Diterpene+saccharide:hybrid/tailoring 48.0 95.7 319.0 7.06e-106
QBG82524.1 cytochrome_P450 BGC0002587.2 PKS 45.0 98.3 314.0 4.97e-104
QBF51762.1 cytochrome_P450 BGC0001856.4 PKS:Type I 45.0 92.1 296.0 8.22e-97
UMM61365.1 Tsk4 BGC0002661.2 NRPS:Type I 45.0 93.3 296.0 9.01e-97
ADG87273.1 cytochrome_P450 BGC0001860.4 ribosomal:RiPP:Thiopeptide 47.0 86.5 294.0 2.13e-96
TXD00264.1 cytochrome_P450 BGC0001877.4 PKS 44.0 91.8 293.0 6.05e-96
CAI94681.1 cytochrome_P450 BGC0000141.5 PKS 44.0 93.5 291.0 1.04e-94
UMM61366.1 Tsk5 BGC0002661.2 NRPS:Type I 44.0 92.1 289.0 5.45e-94
ACR50783.1 P450_monooxygenase BGC0000163.5 PKS 46.0 84.1 286.0 3.44e-93
CAI94726.1 putative_cytochrome_P450 BGC0000141.5 PKS 45.0 92.8 285.0 8.24e-93
NQE92416.1 cytochrome_P450 BGC0002120.3 ribosomal:RiPP:Lanthipeptide 44.0 93.5 285.0 9.7e-93
ACS83778.1 cytochrome_P450_monooxygenase BGC0000613.5 ribosomal:RiPP:Thiopeptide 46.0 87.3 284.0 2.21e-92
ASX95240.1 IlaR BGC0001620.5 NRPS:Type I+PKS 45.0 91.8 282.0 1.27e-91
BBA20966.1 cytochrome_P450 BGC0001763.5 NRPS:Type I+PKS 45.0 91.8 281.0 5.05e-91
ABG02269.1 SalD BGC0000143.5 PKS 45.0 92.3 279.0 2.63e-90
BBA84062.1 cytochrome_p450 BGC0001649.3 PKS 43.0 87.5 276.0 2e-89
QKG20139.1 cytochrome_P450 BGC0002124.3 PKS:Type I 42.0 92.5 275.0 4.29e-89
CAJ42333.1 cytochrome_P450 BGC0000273.5 PKS:Type II+saccharide:hybrid/tailoring 44.0 92.3 275.0 9.8e-89
ADG87274.1 cytochrome_P450 BGC0001860.4 ribosomal:RiPP:Thiopeptide 44.0 91.6 274.0 2.2e-88
ABW00329.1 cytochrome_P450 BGC0000333.5 NRPS:Type I 44.0 86.1 273.0 3.16e-88
AJO72741.1 Cytochrome_P450_monooxygenase BGC0001381.5 PKS 44.0 93.3 273.0 7.44e-88
QIQ28633.1 Nbc37 BGC0002541.2 other:other 41.0 91.3 271.0 3.6e-87
ACS83779.1 cytochrome_P450_monooxygenase BGC0000613.5 ribosomal:RiPP:Thiopeptide 44.0 92.1 268.0 3.88e-86
AGI99476.1 p450_monooxygenase BGC0001004.5 PKS:Type I 42.0 90.6 266.0 2.03e-85
ATL73061.1 hypothetical_protein BGC0001807.4 NRPS:Type I+PKS 42.0 90.6 266.0 2.03e-85
QFU80880.1 p450_monooxygenase BGC0002550.2 PKS 42.0 90.6 266.0 2.03e-85
AGC09505.1 LobA5 BGC0001183.5 PKS 43.0 89.9 265.0 5.7e-85
ctg1_16 BGC0001931.2 PKS 42.0 92.8 264.0 1.57e-84
AHA81987.1 Arm17 BGC0000199.5 PKS:Type II+saccharide:hybrid/tailoring 41.0 94.0 264.0 1.91e-84
WP_053138501.1 cytochrome_P450 BGC0002033.4 PKS 40.0 94.5 257.0 1.09e-81
EWS95123.1 hypothetical_protein BGC0000306.5 NRPS:Type I 42.0 87.0 256.0 2.03e-81
CAM00054.1 cytochrome_P450_Erythromycin_B/D_C-12_hydroxylase BGC0000055.5 PKS:Type I+saccharide:hybrid/tailoring 40.0 93.3 256.0 2.57e-81
QJU69516.1 LooP1 BGC0002460.3 other:other 40.0 91.3 254.0 7e-81
ABL09953.1 oxidoreductase BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 44.0 92.1 256.0 7.49e-81
AAU93795.1 erythromycin_C-12_hydroxylase BGC0000054.5 PKS 40.0 91.8 251.0 1.68e-79
CAG23984.1 putative_cytochrome_P450_monooxygenase BGC0000176.5 PKS 38.0 92.1 248.0 2.56e-78
ACB46465.1 p450_monooxygenase BGC0000082.5 PKS 41.0 92.3 248.0 3.04e-78
ALV86875.1 Tlo29 BGC0001406.5 NRPS:Type I 41.0 89.7 246.0 1.74e-77
ARW71481.1 cytochrome_P450_hydroxylase BGC0001812.3 PKS 38.0 92.8 246.0 2e-77
QLD23833.1 cytochrome_P450 BGC0002086.3 PKS 38.0 92.8 244.0 1.11e-76
BBM96643.1 cytochrome_P450_hydroxylase BGC0002452.2 PKS 38.0 98.6 240.0 3.87e-75
AKG06373.1 cytochrome_P-450 BGC0001830.3 PKS 36.0 92.5 236.0 1.3e-73
AIT55258.1 GulG BGC0000072.5 PKS:Type I 38.0 84.6 234.0 7.46e-73
BAQ25510.1 cytochrome_P450 BGC0001288.5 PKS 40.0 85.8 216.0 4.9e-66
QIS94333.1 Tjp9 BGC0002482.2 other:other 39.0 84.9 216.0 8.48e-66
BAF92583.1 cytochrome_P450_monooxygenase BGC0000118.5 PKS 37.0 91.3 213.0 1.17e-64
ACJ24857.1 putative_cytochrome_P450_monooxygenase BGC0000119.5 PKS:Iterative type I+saccharide:hybrid/tailoring 37.0 91.3 213.0 1.17e-64
QLG04877.1 PulP BGC0002374.2 PKS 43.0 73.8 209.0 4.45e-63
ADC79647.1 TamI BGC0001052.5 NRPS:Type I+PKS:Type I 37.0 85.8 207.0 1.47e-62
CBA11565.1 cytochrome_P450 BGC0001046.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 41.0 83.7 207.0 2.07e-62
CAM00071.1 6-deoxyerythronolide_B_hydroxylase_(6-DEB_hydroxylase) BGC0000055.5 PKS:Type I+saccharide:hybrid/tailoring 38.0 88.7 206.0 3.25e-62
CBA11578.1 cytochrome_P450 BGC0001046.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 39.0 92.3 206.0 4.19e-62
AAM97370.1 RubU BGC0000266.5 PKS 38.0 99.0 203.0 1e-60
ABM21756.1 PdmJ BGC0000256.3 PKS 38.0 89.2 202.0 2.27e-60
AFV52207.1 P450_monooxygenase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 38.0 89.4 201.0 5.83e-60
ADZ45320.1 cytochrome_P450 BGC0001020.5 NRPS:Type I+PKS 39.0 88.2 197.0 1.11e-58
AEF33091.1 cytochrome_P450_family_protein BGC0001039.5 NRPS:Type I+PKS 36.0 92.1 197.0 1.23e-58
ANA09446.1 PriD BGC0001483.4 other:other 35.0 103.6 198.0 1.46e-58
AEC04353.1 cytochrome_P450 BGC0000178.5 PKS:Trans-AT type I 34.0 87.0 197.0 1.65e-58
UMP03492.1 NmvR BGC0002649.2 NRPS:Type I+PKS 39.0 79.1 196.0 3.08e-58
UMP03496.1 NmvG BGC0002649.2 NRPS:Type I+PKS 39.0 91.3 195.0 5.34e-58
CCC55925.1 hypothetical_protein BGC0000973.5 NRPS:Type I+PKS:Type I 38.0 89.4 195.0 6.51e-58
ANY57958.1 cytochrome_p450 BGC0001369.3 PKS 34.0 98.3 196.0 8.76e-58
AXN93609.1 PuwJ BGC0001953.4 NRPS:Type I 38.0 72.8 195.0 1.05e-57
AAT09797.1 NocL BGC0000395.5 NRPS:Type I 38.0 88.0 194.0 1.44e-57
QFU19834.1 cytochrome_P450 BGC0002431.3 PKS+saccharide 40.0 74.3 195.0 1.64e-57
AXN93596.1 PuwJ BGC0001952.3 NRPS:Type I 38.0 72.8 194.0 2.07e-57
ABC02792.1 putative_cytochrome_P450_enzyme BGC0000809.3 other:other 36.0 93.8 193.0 4.27e-57
CAG23962.1 putative_cytochrome_P450_107K1 BGC0001089.5 NRPS:Type I+PKS:Type I 37.0 70.9 193.0 6e-57
ACY13420.1 cytochrome_P450 BGC0001367.5 NRPS:Type I+PKS 37.0 93.3 191.0 1.91e-56
BAC76484.1 P450_hydroxylase_LkmF BGC0000085.5 PKS 38.0 76.0 191.0 2.61e-56
AAQ84164.1 PlmS2 BGC0000123.5 PKS 37.0 90.6 190.0 4.33e-56
QOD95001.1 PldB BGC0002102.2 PKS 36.0 89.2 190.0 4.33e-56
AHE14641.1 cytochrome_P450 BGC0001336.5 other:other 34.0 93.3 190.0 2.95e-55
BAH02272.1 cytochrome_P450 BGC0000126.5 PKS 41.0 70.9 187.0 4.6e-55
AAS79447.1 P450 BGC0000035.5 PKS 36.0 88.0 187.0 5.57e-55
BAC10677.1 putative_cytochrome_P450 BGC0000821.5 other:other 36.0 88.7 187.0 6.14e-55
AAF81737.1 putative_p450_monooxygenase_EncR BGC0000220.4 PKS:Type II 36.0 98.1 187.0 6.76e-55
ANC94978.1 AlmPIII BGC0001396.5 PKS 36.0 92.1 187.0 7.8e-55
UMM61375.1 Tsk14 BGC0002661.2 NRPS:Type I 35.0 94.7 186.0 1.61e-54
AKG47163.1 HysP BGC0001223.5 other:other 36.0 93.5 186.0 1.69e-54
AFV52184.1 acyl-CoA_synthetase/P450_monooxygenase BGC0000081.5 NRPS:Type I+PKS:Iterative type I 37.0 88.9 194.0 2.69e-54
ABB52528.1 cytochrome_P-450 BGC0000047.5 PKS 36.0 92.1 186.0 3e-54
QZA73303.1 cytochrome_P450 BGC0002385.3 PKS 39.0 77.2 186.0 3.15e-54
AKT74275.1 TxnO2 BGC0002141.3 PKS 41.0 73.1 185.0 5.11e-54
AKT74289.1 TxnO6 BGC0002141.3 PKS 36.0 87.3 185.0 5.75e-54
AEC13077.1 fosK BGC0000060.5 PKS 37.0 92.1 184.0 9.33e-54
EHK80160.1 cytochrome_p450-like_enzyme BGC0001447.3 PKS 39.0 80.8 184.0 1.34e-53
QVV57681.1 6-deoxyerythronolide_B_hydroxylase BGC0002338.3 PKS 35.0 88.2 184.0 1.73e-53
QIC03931.1 EncR BGC0002366.2 PKS 36.0 93.8 183.0 1.96e-53
ctg3_7 BGC0001853.3 NRPS:Type I+PKS:Type I 38.0 73.6 184.0 2.09e-53
ANW12113.1 putative_cytochrome_P450 BGC0001374.5 other:other 34.0 89.9 182.0 6.87e-53
AAU93799.1 cytochrome_P450_oxidoreductase BGC0000054.5 PKS 37.0 90.1 182.0 8.48e-53
ABB88518.1 cytochrome_450_monooxygenase BGC0000050.5 PKS 37.0 78.6 182.0 8.95e-53
ADC45514.1 cytochrome_P450 BGC0000093.5 PKS:Type I 36.0 89.4 181.0 9.84e-53
AAN85514.1 cytochrome_P450_hydroxylase BGC0001101.5 NRPS:Type I+PKS:Type I 36.0 86.3 181.0 1.41e-52
ABC84463.1 NigD BGC0000114.5 PKS:Type I 34.0 93.0 181.0 1.6e-52
AGI62224.1 cytochrome_P450 BGC0001335.5 other:other 40.0 71.2 181.0 1.86e-52
QKV49775.1 cytochrome_P450 BGC0002526.3 PKS 37.0 80.8 181.0 2.14e-52
WP_235558178.1 cytochrome_P450 BGC0001653.3 PKS 41.0 69.0 187.0 4.48e-52
QWF78542.1 Biotin_biosynthesis_cytochrome_P450 BGC0002142.2 PKS 39.0 73.6 180.0 6.4e-52
ACN29722.1 cytochrome_P450 BGC0000814.3 other:other 38.0 70.9 179.0 6.82e-52
AFV30254.1 cytochrome_P450 BGC0000075.5 PKS 38.0 70.9 179.0 1.06e-51
QDQ37886.1 cytochrome_P450 BGC0001979.4 PKS 36.0 87.7 179.0 1.25e-51
AUD08664.1 cytochrome_P450 BGC0001553.5 NRPS:Type I+PKS 34.0 97.1 178.0 1.38e-51
AVL27080.1 cytochrome_P450 BGC0001485.4 other:other 36.0 79.8 178.0 1.66e-51
BAJ52675.1 putative_cytochrome_P450 BGC0000222.5 PKS 37.0 83.9 179.0 1.67e-51
AJV88386.1 MfnN BGC0001214.5 NRPS:Type I 37.0 74.0 179.0 1.87e-51
TMU97096.1 cytochrome_P450 BGC0002038.2 PKS 33.0 93.0 178.0 2.34e-51
QDQ37897.1 cytochrome_P450 BGC0001979.4 PKS 40.0 73.1 178.0 2.55e-51
ARS01480.1 NcmG BGC0001702.3 NRPS:Type I+PKS 38.0 87.7 177.0 2.77e-51
BAC76495.1 P450_hydroxylase_LkmK BGC0000085.5 PKS 35.0 87.0 177.0 4.55e-51
QKV49782.1 cytochrome_P450 BGC0002526.3 PKS 35.0 90.4 177.0 4.67e-51
BAJ52696.1 putative_cytochrome_P450 BGC0000222.5 PKS 38.0 89.7 177.0 6.39e-51
AEZ53958.1 putative_cytochrome_P450 BGC0000144.5 PKS:Type I 33.0 88.9 177.0 6.82e-51
ABO15856.1 cytochrome_P450 BGC0000130.5 PKS 34.0 90.1 176.0 9.11e-51
ALV86869.1 Tlo23 BGC0001406.5 NRPS:Type I 34.0 83.7 176.0 1.14e-50
ANY57978.1 Cytochrome_P450 BGC0001369.3 PKS 37.0 91.3 176.0 1.19e-50
QIC03957.1 CyaH BGC0002347.3 other:other 37.0 89.7 176.0 1.78e-50
ASZ00162.1 cytochrome_P450 BGC0001785.5 PKS 34.0 101.2 176.0 2.33e-50
AKG47114.1 RedP BGC0001224.5 other:other 36.0 86.8 174.0 3.3e-50
WJJ09229.1 cytochrome_P450 BGC0002810.2 NRPS:Type I+PKS 41.0 71.2 175.0 3.98e-50
AGN74891.1 P450-like_monooxygenase BGC0000459.5 NRPS:Type I+PKS:Trans-AT type I 34.0 94.0 174.0 5.54e-50
ABV98189.1 cytochrome_P450 BGC0000827.3 other:other 37.0 83.7 174.0 8.88e-50
AHB38510.1 EpnI BGC0000345.5 NRPS:Type I+PKS:Type I 33.0 87.3 174.0 1.68e-49
QLD23834.1 cytochrome_P450 BGC0002086.3 PKS 33.0 87.7 173.0 1.74e-49
ARM20265.1 SauP2 BGC0002591.2 PKS+terpene 38.0 74.5 173.0 2.2e-49
AAG06719.1 cytochrome_P450 BGC0002037.3 NRPS:Type I 37.0 72.1 173.0 2.47e-49
QNH67553.1 Cip25 BGC0002108.3 NRPS:Type I 31.0 94.0 173.0 2.7e-49
QEA08904.1 JenP2 BGC0002559.2 PKS 35.0 92.1 173.0 2.94e-49
ARW71482.1 cytochrome_P450_epoxidase BGC0001812.3 PKS 33.0 87.7 172.0 3.39e-49
BCB17037.1 putative_cytochrome_P450 BGC0002523.2 NRPS:Type I 36.0 78.6 172.0 5.37e-49
ATV95604.1 cytochrome_P450_monooxygenase BGC0001503.4 PKS 35.0 92.5 172.0 5.53e-49
BAC55212.1 cytochrome_P450 BGC0000825.5 other:other 38.0 71.6 171.0 9.2e-49
QWM97863.1 cytochrome_P450 BGC0002434.2 PKS+NRPS:Type I 37.0 82.9 171.0 9.6e-49
QBG38788.1 Atr27 BGC0001975.4 NRPS:Type I 30.0 94.5 171.0 1.05e-48
ARG41922.1 IstS BGC0001622.5 PKS 36.0 90.1 171.0 1.08e-48
ABP73648.1 SalD BGC0000145.5 NRPS:Type I+PKS 31.0 84.4 169.0 6.8e-48
ABP53495.1 cytochrome_P450 BGC0001041.4 NRPS:Type I+PKS 31.0 84.4 169.0 8.06e-48
CBD77752.1 cytochrome_P450 BGC0000974.5 NRPS:Type I+PKS 36.0 76.4 169.0 9.09e-48
BAE98161.1 putative_cytochrome_P450 BGC0000339.5 NRPS:Type I 31.0 89.9 168.0 1.15e-47
BAH04170.1 putative_cytochrome_P450 BGC0000450.5 NRPS:Type I 32.0 89.4 168.0 1.31e-47
ADB02836.1 AzicO2 BGC0000202.5 PKS 34.0 90.4 167.0 1.79e-47
ACB47071.1 putative_cytochrome_P450_hydroxylase BGC0001060.5 PKS 38.0 72.6 167.0 3.48e-47
ACY01404.1 hydroxylase BGC0000083.5 PKS:Type I 35.0 82.7 167.0 3.67e-47
ANY94454.1 P450_hydroxylase BGC0001584.5 PKS 40.0 76.2 166.0 7.45e-47
ctg1_orf525 BGC0001199.5 PKS 38.0 70.2 165.0 1.26e-46
CAC11139.1 NikQ_protein BGC0000876.5 other:other 32.0 86.8 165.0 1.69e-46
AJD77035.1 cytochrome_P450 BGC0001435.4 NRPS:Type I+PKS:Iterative type I 37.0 74.0 166.0 1.85e-46
BAL90275.1 putative_cytochrome_P450 BGC0002021.3 PKS 37.0 88.2 164.0 2.52e-46
BAB69197.1 cytochrome_P450 BGC0000117.5 PKS 36.0 83.4 164.0 2.8e-46
AEC13073.1 fosG BGC0000060.5 PKS 30.0 94.2 164.0 3.12e-46
ACN29715.1 cytochrome_P450_hydroxylase BGC0000814.3 other:other 37.0 83.9 164.0 3.44e-46
CBG74929.1 putative_monooxygenase BGC0002808.2 PKS:Type I 36.0 79.3 164.0 3.44e-46
AET98913.1 putative_cytochrome_P450 BGC0000415.5 NRPS:Type I 31.0 89.4 164.0 3.67e-46
AEF32101.1 RebP-like_cytochrome_P450 BGC0001333.5 other:other 33.0 85.8 164.0 4.21e-46
QWT72280.1 cytochrome_P450 BGC0002430.3 NRPS:Type I+saccharide 40.0 71.6 164.0 4.62e-46
QDJ74279.1 cytochrome_P450 BGC0002109.3 NRPS:Type I 34.0 85.3 163.0 7.93e-46
AZM57027.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 36.0 83.4 162.0 1.93e-45
AAY28212.1 unknown BGC0000074.5 PKS 33.0 93.8 162.0 2.76e-45
CAJ34365.1 quinaldate_3-hydroxylase BGC0000445.5 NRPS:Type I 31.0 87.3 162.0 2.87e-45
ALU98532.1 cytochrome BGC0001397.5 NRPS:Type I+PKS 39.0 76.2 161.0 4.83e-45
CAJ88189.1 putative_cytochrome_P450 BGC0000151.5 PKS:Type I+saccharide:hybrid/tailoring 36.0 76.7 161.0 5.24e-45
AAL06684.1 P450_hydroxylase BGC0000965.5 PKS:Iterative type I 39.0 76.2 161.0 5.35e-45
AEW98143.1 putative_cytochrome_P450 BGC0002642.2 other:other 34.0 95.0 161.0 5.7e-45
BAF98633.1 putative_P450 BGC0000651.5 terpene 34.0 88.9 160.0 1.06e-44
AEO12713.1 cytochrome_P450 BGC0001334.5 other:other 36.0 83.2 160.0 1.08e-44
AKQ20689.1 RebP-like_cytochrome_p450 BGC0001337.5 other:other 37.0 70.9 159.0 1.71e-44
QIE07135.1 OvmQ BGC0001719.4 PKS 35.0 82.2 158.0 2.51e-44
ABB52529.1 cytochrome_P-450 BGC0000047.5 PKS 40.0 71.9 159.0 2.76e-44
AEA60655.1 cytochrome_P450 BGC0000892.4 other:other 33.0 72.1 159.0 3.61e-44
CCP20055.1 divQ_protein BGC0001119.5 PKS:Type I 35.0 82.2 158.0 4.72e-44
CAJ88188.1 putative_cytochrome_P450 BGC0000151.5 PKS:Type I+saccharide:hybrid/tailoring 36.0 75.0 158.0 6.98e-44
ATL73031.1 cytochrome_P450_hydroxylase BGC0001807.4 NRPS:Type I+PKS 35.0 84.1 157.0 1.45e-43
OKI81364.1 cytochrome BGC0002478.3 PKS 33.0 91.8 157.0 1.51e-43
AZM50113.1 cytochrome_P450 BGC0002702.3 NRPS:Type I 35.0 90.4 157.0 1.54e-43
AEA30275.1 P450_monooxygenase BGC0000429.4 NRPS:Type I+PKS 32.0 87.0 157.0 1.62e-43
ASZ00146.1 cytochrome_P450 BGC0001785.5 PKS 34.0 89.2 157.0 1.85e-43
AGI62211.1 RebP-like_cytochrome_P450 BGC0001335.5 other:other 34.0 78.8 157.0 2.16e-43
TXJ86095.1 cytochrome_P450 BGC0002789.2 PKS:Modular type I 34.0 83.9 156.0 2.69e-43
ABV91294.1 probable_cytochrome_P450 BGC0000158.5 PKS:Type I 33.0 76.0 157.0 3.67e-43
QVQ62851.1 cytochrome_P450 BGC0002373.3 NRPS:Type I 30.0 95.4 156.0 4.1e-43
ABW00322.1 cytochrome_P450 BGC0000333.5 NRPS:Type I 33.0 80.0 156.0 4.15e-43
AEW98132.1 cytochrome_P450-like_enzyme BGC0002642.2 other:other 33.0 95.2 155.0 5.32e-43
QYA95679.1 cytochrome_P450 BGC0002676.2 NRPS:Type I 31.0 87.0 156.0 6.05e-43
QQZ01646.1 cytochrome_P450 BGC0002497.3 other:other 34.0 95.4 155.0 6.14e-43
AEK75512.1 cytochrome_P450 BGC0000001.5 PKS:Type I 35.0 86.1 155.0 6.69e-43
AWH12632.1 Rmp16 BGC0001759.3 PKS 32.0 95.2 155.0 7.93e-43
QKW60390.1 cytochrome_P450 BGC0002288.2 NRPS:Type I 35.0 85.6 155.0 9.62e-43
BAP82653.1 cytochrome_P450 BGC0001148.5 NRPS:Type I+ribosomal:RiPP 35.0 89.7 155.0 1.18e-42
EFG04601.1 Staurosporine_biosynthesis_cytochrome_P450_StaP BGC0000826.5 other:other 37.0 75.5 156.0 1.23e-42
ALJ49912.1 TlmF BGC0001237.5 PKS 36.0 79.6 154.0 2.22e-42
AJW65400.1 cytochrome_P450_monooxygenase BGC0001195.3 NRPS:Type I+PKS 33.0 88.7 154.0 2.64e-42
ctg3_35 BGC0001853.3 NRPS:Type I+PKS:Type I 36.0 73.6 154.0 2.64e-42
AKG06374.1 cytochrome_P-450 BGC0001830.3 PKS 32.0 88.5 153.0 5.72e-42
AVV61990.1 cytochrome_P450 BGC0001477.5 NRPS:Type I+PKS:Type I 31.0 95.0 153.0 6.79e-42
AYU66269.1 TjhO6 BGC0002461.2 PKS 32.0 99.3 152.0 1.11e-41
WP_003071775.1 cytochrome_P450 BGC0002009.4 PKS 32.0 97.4 152.0 2.1e-41
QHZ99325.1 cytochrome_P450_monooxygenase BGC0001875.4 PKS:Type I 31.0 85.8 152.0 2.14e-41
CBW54668.1 putative_cytochrome_P450 BGC0000971.5 NRPS:Type I+PKS:Type I 35.0 95.7 151.0 2.91e-41
UWK15756.1 LasP BGC0002153.2 PKS 31.0 93.8 151.0 3.54e-41
ADM46355.1 cytochrome_P450-like_protein BGC0000106.5 PKS 33.0 95.9 150.0 5.1e-41
AFW04584.1 cytochrome_P450 BGC0001783.5 other:other 38.0 73.6 150.0 6.58e-41
CQR60498.1 Rif-orf0(cero)_homologue,_Cytochrome_P450 BGC0001287.5 PKS 33.0 90.1 150.0 7.1e-41
ASZ00142.1 cytochrome_P450 BGC0001785.5 PKS 34.0 86.3 150.0 9.55e-41
AWH12672.1 Rmp0 BGC0001759.3 PKS 33.0 90.6 149.0 9.67e-41
QGA70089.1 cytochrome_P450 BGC0002517.3 PKS 35.0 76.9 149.0 1.29e-40
AAC01709.1 putative_cytochrome_P450-like_protein BGC0000136.5 PKS 33.0 90.6 149.0 1.87e-40
AEI58880.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 30.0 89.7 149.0 1.87e-40
RSO11790.1 cytochrome_P450 BGC0002637.3 NRPS:Type I 33.0 85.1 148.0 2.6e-40
BAF98628.1 putative_P450 BGC0000651.5 terpene 30.0 89.9 148.0 5.48e-40
ABV97150.1 cytochrome_P450 BGC0000137.3 PKS 33.0 90.9 147.0 9.87e-40
BBM95957.1 cytochrome_P450 BGC0002558.2 PKS 32.0 86.1 147.0 1.04e-39
DAB41480.1 cytochrome_P450 BGC0001230.5 NRPS:Type I+PKS:Type I 34.0 71.9 147.0 1.09e-39
ABB69759.1 PlaO4 BGC0000654.4 terpene:Diterpene+saccharide:hybrid/tailoring 35.0 84.9 146.0 1.22e-39
ACO31280.1 PtmO5 BGC0001140.5 terpene:Diterpene 34.0 100.7 147.0 1.31e-39
ABV97165.1 cytochrome_P450 BGC0000137.3 PKS 32.0 101.0 147.0 1.55e-39
BBA20960.1 cytochrome_P450 BGC0001763.5 NRPS:Type I+PKS 33.0 77.2 145.0 1.78e-39
OKA09437.1 NikQ_protein BGC0001459.5 NRPS:Type I 29.0 89.9 146.0 1.87e-39
AXG22409.1 cytochrome_P450 BGC0002024.3 PKS:Type I 30.0 87.7 146.0 2.11e-39
ASX95234.1 IlaL BGC0001620.5 NRPS:Type I+PKS 33.0 77.2 145.0 4.03e-39
AAC01740.2 putative_cytochrome_P450_monooxygenase BGC0000136.5 PKS 31.0 96.2 144.0 6.06e-39
ACB47070.1 putative_cytochrome_P450_hydroxylase BGC0001060.5 PKS 33.0 90.4 144.0 1.1e-38
QXL90821.1 cytochrome_P450 BGC0002426.3 NRPS:Type I 32.0 90.4 144.0 1.14e-38
ANH11399.1 SceD BGC0001770.4 PKS 33.0 72.8 144.0 1.16e-38
AWH12925.1 StmP3 BGC0001784.5 PKS 30.0 96.9 144.0 1.24e-38
WP_003060232.1 cytochrome_P450 BGC0002009.4 PKS 32.0 90.6 143.0 2.57e-38
QBL56209.1 cytochrome_P450_hydroxylase BGC0002376.2 PKS 37.0 74.3 143.0 2.63e-38
ADE22287.1 putative_cytochrome_P450_hydroxylase BGC0000279.5 PKS 33.0 72.4 143.0 2.77e-38
MCC5036791.1 cytochrome_P450 BGC0002638.3 NRPS:Type I 33.0 83.7 142.0 4.61e-38
CAC17503.1 putative_cytochrome_P450 BGC0000324.5 NRPS:Type I 31.0 89.7 142.0 4.7e-38
QGA70088.1 cytochrome_P450 BGC0002517.3 PKS 32.0 72.8 142.0 6.39e-38
AEK75493.1 cytochrome_P450 BGC0000001.5 PKS:Type I 31.0 93.3 141.0 9.52e-38
OLZ50900.1 NikQ_protein BGC0001461.5 NRPS:Type I 29.0 90.6 141.0 9.52e-38
AYA22317.1 OxyD BGC0001955.4 saccharide+NRPS:Type I 29.0 90.6 141.0 9.52e-38
ATL73037.1 cytochrome_P450_hydroxylase BGC0001807.4 NRPS:Type I+PKS 33.0 82.9 141.0 1.08e-37
AGC09527.1 cytochrome_P450 BGC0001183.5 PKS 33.0 82.9 141.0 1.12e-37
QKG20138.1 cytochrome_P450 BGC0002124.3 PKS:Type I 32.0 102.2 140.0 1.97e-37
AFI57027.1 cytochrome_p450 BGC0000133.5 PKS 31.0 89.4 140.0 2.08e-37
UMP03495.1 NmvS BGC0002649.2 NRPS:Type I+PKS 31.0 95.2 140.0 3.52e-37
QVN25654.1 P450_monooxygenase BGC0002363.3 ribosomal:RiPP 30.0 88.9 139.0 5.24e-37
ANH11400.1 SceE BGC0001770.4 PKS 34.0 73.8 139.0 5.63e-37
WP_020636808.1 cytochrome_P450 BGC0002011.3 PKS 36.0 79.3 139.0 7.93e-37
QGJ79685.1 Cytochrome_P450_monooxygenase BGC0002552.2 PKS 36.0 79.3 139.0 7.93e-37
CCH32732.1 Cytochrome_P450_monooxygenase BGC0002070.3 PKS 31.0 85.3 139.0 8.7e-37
QIJ31506.1 SgdE10 BGC0002545.3 PKS 31.0 89.9 139.0 1.35e-36
DAC80080.1 cytochrome_P450 BGC0001835.2 PKS 30.0 73.6 138.0 1.72e-36
AIE77077.1 p450_monooxygenase BGC0000418.5 NRPS:Type I 30.0 81.2 138.0 1.79e-36
AAK81831.1 P450-related_oxidase BGC0000326.5 NRPS:Type I 34.0 84.4 138.0 1.83e-36
AVX51103.1 nysN BGC0001709.5 PKS 32.0 86.8 138.0 1.86e-36
ABA41523.1 cytochrome_P450_hydroxylase BGC0000722.5 other:cyclitol+saccharide 36.0 79.1 137.0 1.94e-36
DAC80537.1 cytochrome_P450 BGC0001840.2 NRPS:Type I+PKS 32.0 73.8 138.0 2.59e-36
ACB46198.1 cytochrome_P450 BGC0000989.3 NRPS:Type I+PKS 32.0 87.7 138.0 2.68e-36
AAM80533.1 StaH BGC0000290.5 NRPS:Type I 32.0 75.0 137.0 3.57e-36
AIG79223.1 Hypothetical_protein BGC0000419.5 NRPS:Type I+saccharide 29.0 90.6 136.0 6.6e-36
QCF28931.1 cytochrome_P450_hydroxylase BGC0002308.2 other:other+PKS 35.0 72.6 136.0 9.62e-36
AEC13076.1 fosJ BGC0000060.5 PKS 30.0 89.4 136.0 1.37e-35
AAM80534.1 StaG BGC0000290.5 NRPS:Type I 32.0 84.1 135.0 1.41e-35
AKA59441.1 cytochrome_P450_hydroxylase BGC0001202.4 NRPS:Type I+PKS 28.0 92.3 134.0 3.65e-35
QBG82523.1 cytochrome_P450 BGC0002587.2 PKS 31.0 72.8 134.0 3.84e-35
ABV83225.1 CppN BGC0000116.5 PKS 32.0 87.5 134.0 6.17e-35
OKA09428.1 cytochrome BGC0001459.5 NRPS:Type I 32.0 73.8 134.0 6.63e-35
AAF26924.1 cytochrome_P450 BGC0000988.5 NRPS:Type I+PKS 31.0 87.5 134.0 6.8e-35
AAF62886.1 EpoK BGC0000991.4 NRPS:Type I+PKS 30.0 88.7 134.0 6.8e-35
UID85536.1 biotin_biosynthesis_cytochrome_P450 BGC0002631.2 ribosomal:RiPP:Biarylitide 32.0 86.5 133.0 7.43e-35
QBA57766.1 cytochrome_P450 BGC0002377.2 NRPS:Type I 30.0 78.1 134.0 7.72e-35
AAO06929.1 GdmP BGC0000066.5 PKS 34.0 73.1 133.0 1.24e-34
AAZ77695.1 ChlE2 BGC0000036.5 PKS:Type I+saccharide:oligosaccharide 36.0 74.0 133.0 1.27e-34
AIE77064.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 32.0 77.2 133.0 1.27e-34
ADB12494.1 EpoK BGC0000990.3 NRPS:Type I+PKS 32.0 79.1 133.0 1.3e-34
AAK06805.1 putative_cytochrome_P450_oxidase_SimD1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 28.0 93.5 133.0 1.34e-34
AAL15601.1 SimI BGC0000270.5 PKS 28.0 93.5 133.0 1.71e-34
ALG65320.1 Cal16 BGC0001297.4 NRPS:Type I 30.0 78.1 132.0 2.81e-34
AAF71771.1 NysN BGC0000115.5 PKS:Type I+saccharide:hybrid/tailoring 31.0 84.4 132.0 3.34e-34
CAA76548.1 P450_monooxygenase BGC0000311.6 saccharide+NRPS:Type I 34.0 73.8 131.0 6.38e-34
OLZ52453.1 cytochrome BGC0001462.5 NRPS:Type I 32.0 75.0 130.0 8.81e-34
ABJ97440.1 MerD BGC0001012.3 NRPS:Type I+PKS 36.0 72.1 129.0 1.06e-33
AGS77323.1 OxyB_monooxygenase BGC0001178.5 NRPS:Type I 31.0 75.0 130.0 1.22e-33
AAK81832.1 P450-related_oxidase BGC0000326.5 NRPS:Type I 29.0 94.7 130.0 1.31e-33
AAG13924.1 C-6_hydroxylase BGC0000092.5 PKS 44.0 37.0 124.0 1.59e-33
AAY28237.1 HbmP BGC0000074.5 PKS 30.0 91.1 129.0 2.28e-33
AIG79237.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 31.0 85.6 129.0 3.56e-33
ABC87513.1 cytochrome_P450_monooxygenase BGC0001011.5 NRPS:Type I+PKS 29.0 92.3 128.0 5.99e-33
ctg1_orf24 BGC0001013.5 NRPS:Type I+PKS 29.0 92.3 128.0 5.99e-33
CAC20928.1 PimG_protein BGC0000125.5 PKS 32.0 84.9 128.0 6.09e-33
AIG79236.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 32.0 77.2 128.0 6.09e-33
AQT01386.1 SgnG BGC0001690.5 PKS 32.0 84.9 128.0 6.09e-33
AHB38512.1 EpnK BGC0000345.5 NRPS:Type I+PKS:Type I 29.0 89.7 128.0 6.39e-33
QYC40293.1 Crosslinking_oxygenase_OxyC BGC0002344.2 NRPS:Type I 30.0 91.6 128.0 6.67e-33
AQZ69231.1 hypothetical_protein BGC0001635.4 NRPS:Type I+PKS 34.0 73.8 128.0 7.01e-33
CAE53360.1 Oxy_protein BGC0000440.5 NRPS:Type I 30.0 94.7 127.0 9.2e-33
CAG15018.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 30.0 94.7 127.0 9.2e-33
AAR16519.1 RimG BGC0000138.5 PKS 33.0 80.8 128.0 1.18e-32
WP_003985474.1 cytochrome_P450 BGC0002106.3 PKS:Modular type I 33.0 80.8 128.0 1.18e-32
CAO85895.1 cytochrome_P-450_monooxygenase BGC0000110.5 PKS:Type I 32.0 80.3 127.0 1.81e-32
ABY83170.1 Azi32 BGC0000960.5 NRPS:Type I+PKS 31.0 73.6 127.0 2.21e-32
QUQ72343.1 cytochrome_P450 BGC0002349.3 PKS:Type I 32.0 89.2 126.0 3.66e-32
CAD91207.1 putative_OxyB_monooxigenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 31.0 75.7 126.0 4.19e-32
AIE77063.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 30.0 86.1 125.0 4.68e-32
WP_010875296.1 cytochrome_P450 BGC0001605.3 terpene 32.0 77.2 127.0 5.76e-32
BBC27538.1 cytochrome_P450_monooxygenase BGC0001529.5 other:other 31.0 73.6 126.0 8.46e-32
EDY47130.1 cytochrome_P450-SU2 BGC0000845.5 other:non-nrp beta-lactam 33.0 73.3 125.0 9.27e-32
CAG15019.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 32.0 75.0 124.0 1.23e-31
QIZ24106.1 cytochrome_P450_monooxygenase BGC0002540.3 PKS 32.0 78.8 124.0 1.86e-31
OLZ50888.1 cytochrome BGC0001461.5 NRPS:Type I 32.0 73.6 124.0 2.08e-31
AYA22329.1 OxyB BGC0001955.4 saccharide+NRPS:Type I 32.0 73.6 124.0 2.08e-31
CAA11798.1 PCZA363.7 BGC0000322.3 NRPS:Type I 31.0 73.8 124.0 2.35e-31
CAE53361.1 OxyB_protein BGC0000440.5 NRPS:Type I 32.0 75.0 124.0 2.86e-31
QYC40292.1 Crosslinking_oxygenase_OxyA BGC0002344.2 NRPS:Type I 31.0 73.1 123.0 3.65e-31
OJF16276.1 AceN BGC0001491.3 PKS 32.0 76.2 123.0 4.38e-31
RSO11549.1 cytochrome_P450 BGC0002637.3 NRPS:Type I 30.0 85.6 121.0 2.92e-30
AZM50112.1 cytochrome_P450 BGC0002702.3 NRPS:Type I 29.0 83.9 120.0 3.11e-30
WP_102918849.1 cytochrome_P450 BGC0002104.3 NRPS:Type I+PKS:Type I 31.0 91.1 120.0 3.36e-30
BAJ16472.1 cytochrome_P450 BGC0000058.5 PKS 35.0 72.4 121.0 3.36e-30
CAD91208.1 putative_monooxygenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 30.0 94.0 120.0 4.09e-30
AAQ82557.1 FscP BGC0000034.5 NRPS:Type I+PKS 32.0 78.8 120.0 4.69e-30
AKG47164.1 HysX1 BGC0001223.5 other:other 33.0 72.6 120.0 4.81e-30
ABX71093.1 Lct10 BGC0000238.5 PKS 32.0 84.9 121.0 4.84e-30
QYC40294.1 Crosslinking_oxygenase_OxyB BGC0002344.2 NRPS:Type I 31.0 75.7 120.0 5.05e-30
AHH99927.1 cytochrome_P450_hydroxylase BGC0000002.5 PKS 32.0 75.2 120.0 7.46e-30
QHZ99331.1 cytochrome_P450 BGC0001875.4 PKS:Type I 31.0 86.5 119.0 8e-30
AIE77065.1 p450_monooxygenase-like_protein BGC0000418.5 NRPS:Type I 29.0 90.1 120.0 8.58e-30
ARM20255.1 SauP1 BGC0002591.2 PKS+terpene 35.0 63.7 120.0 9.42e-30
QSE03589.1 Lcm6 BGC0002333.3 PKS 30.0 84.6 119.0 1.2e-29
CAE02604.1 putative_cytochrome_P450 BGC0000024.5 PKS:Type I 30.0 71.4 119.0 1.47e-29
AEI58869.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 31.0 73.8 119.0 1.49e-29
ACN29717.1 cytochrome_P450_monooxygenase BGC0000814.3 other:other 35.0 75.5 119.0 1.8e-29
AAM77997.1 cytochrome_P-450 BGC0000112.5 PKS:Iterative type I 31.0 70.9 119.0 2.13e-29
AIG79235.1 Cytochrome_P450 BGC0000419.5 NRPS:Type I+saccharide 29.0 90.1 118.0 3.04e-29
QIQ28629.1 Nbc33 BGC0002541.2 other:other 31.0 78.8 118.0 3.59e-29
ADR01067.1 NocB BGC0000609.3 ribosomal:RiPP:Thiopeptide 30.0 85.8 117.0 9.28e-29
CAD91209.1 putative_OxyA_monooxygenase BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 29.0 83.2 116.0 1.12e-28
EME52985.1 cytochrome_P450_FAS1 BGC0001460.5 NRPS:Type I 31.0 73.8 116.0 1.21e-28
NP_391386.1 cyclo-L-leucyl-L-leucyl_dipeptide_oxidase,_pulcheriminic_synthase BGC0002103.2 other:other 26.0 93.5 116.0 1.33e-28
QDG75027.1 cytochrome_P450 BGC0002068.3 NRPS:Type I+PKS 28.0 94.0 116.0 1.91e-28
AKG47165.1 HysX2 BGC0001223.5 other:other 31.0 79.8 115.0 2.91e-28
OLZ50889.1 cytochrome BGC0001461.5 NRPS:Type I 29.0 83.4 115.0 3.46e-28
AYA22328.1 OxyC BGC0001955.4 saccharide+NRPS:Type I 29.0 83.2 115.0 3.46e-28
AGS77326.1 OxyC_monooxygenase BGC0001178.5 NRPS:Type I 30.0 73.6 115.0 4.99e-28
QIQ28632.1 Nbc36 BGC0002541.2 other:other 30.0 77.4 113.0 1.58e-27
AXG22415.1 Cytochrome_P450 BGC0002024.3 PKS:Type I 31.0 88.2 113.0 1.65e-27
AYA22331.1 OxyA BGC0001955.4 saccharide+NRPS:Type I 29.0 83.2 112.0 4.01e-27
CAI94704.1 putative_cytochrome_P450 BGC0000141.5 PKS 30.0 86.1 112.0 4.27e-27
OLZ50937.1 cytochrome BGC0001461.5 NRPS:Type I 29.0 83.2 112.0 4.56e-27
QYC40295.1 Croslinking_oxygenase_OxyE BGC0002344.2 NRPS:Type I 28.0 82.9 110.0 2.82e-26
AEI58870.1 p450_monooxygenase BGC0000455.6 saccharide+NRPS:Type I 27.0 88.5 109.0 3.81e-26
OKA09429.1 cytochrome BGC0001459.5 NRPS:Type I 27.0 88.5 109.0 3.81e-26
ACN52301.1 TsrK BGC0000614.5 ribosomal:RiPP:Thiopeptide 31.0 71.9 109.0 4.6e-26
CAA76549.1 P450_monooxygenase BGC0000311.6 saccharide+NRPS:Type I 27.0 88.5 109.0 5.2e-26
AAM80531.1 StaJ BGC0000290.5 NRPS:Type I 28.0 83.7 108.0 8.18e-26
AZM57026.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 30.0 84.6 108.0 8.37e-26
QBF51800.1 cytochrome_P450 BGC0001856.4 PKS:Type I 32.0 74.3 108.0 1.31e-25
ACN80655.1 SioR BGC0000611.5 ribosomal:RiPP:Thiopeptide 32.0 70.9 107.0 2.57e-25
AZM57025.1 cytochrome_P450 BGC0002314.3 NRPS:Type I 31.0 74.0 105.0 1.49e-24
CAD91206.1 putative_oxygenase_OxyC BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 27.0 82.9 104.0 2.48e-24
OLZ52451.1 cytochrome BGC0001462.5 NRPS:Type I 27.0 83.9 103.0 4.15e-24
EME52984.1 cytochrome_P450_FAS1 BGC0001460.5 NRPS:Type I 27.0 83.2 103.0 7.37e-24
AAM80535.1 StaF BGC0000290.5 NRPS:Type I 27.0 74.0 102.0 1.16e-23
AGS77321.1 OxyA_monooxygenase BGC0001178.5 NRPS:Type I 27.0 91.6 100.0 7.36e-23
AAW49314.1 putative_cytochrome_P450 BGC0000444.5 NRPS:Type I 28.0 94.2 100.0 8.58e-23
AWH12921.1 StmP2 BGC0001784.5 PKS 29.0 86.5 100.0 9.9e-23
CAE53359.1 OxyA_protein BGC0000440.5 NRPS:Type I 29.0 82.5 99.0 1.36e-22
CAG15017.1 P450_monooxygenase BGC0000441.4 NRPS:Type I 29.0 82.5 99.0 1.36e-22
ABV98185.1 Cytochrome_P450-like_protein BGC0000827.3 other:other 28.0 78.6 97.0 1.35e-21
OLZ52454.1 cytochrome BGC0001462.5 NRPS:Type I 28.0 85.1 96.0 2.13e-21
QEI22735.1 P450 BGC0001986.3 other:other 27.0 90.9 86.0 6.12e-18
ABD59210.1 InkY BGC0000813.3 other:other 40.0 33.9 81.0 1.11e-17
ABI22130.1 cytochrome_P450_hydroxylase BGC0000422.5 NRPS:Type I 26.0 84.9 76.0 2.1e-14
ABW91149.1 NDP-hexose_3,4-isomerase BGC0000019.5 PKS 29.0 76.4 71.0 8.16e-13