LOCUS       NZ_CP032146            22598 bp    DNA     circular CON 27-SEP-2024
DEFINITION  Bacillus amyloliquefaciens strain YP6 chromosome, complete genome.
ACCESSION   NZ_CP032146
VERSION     NZ_CP032146.1
KEYWORDS    RefSeq.
SOURCE      Bacillus amyloliquefaciens
  ORGANISM  Bacillus amyloliquefaciens
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 4009619)
  AUTHORS   Meng,D., Li,J., Huang,L., Zhai,X.L., Tian,P.Q., Guan,B.Z., Cai,J.Y.
            and Liao,R.X.
  TITLE     Complete genome sequence of Bacillus amyloliquefaciens YP6, a plant
            growth promoting rhizobacteria efficiently degrading a wide range of
            organophosphorus pesticides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4009619)
  AUTHORS   Meng,D., Li,J., Huang,L., Zhai,X.L., Tian,P.Q., Guan,B.Z., Cai,J.Y.
            and Liao,R.X.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2019) Key Laboratory of Industrial Biotechnology,
            Ministry of Education, School of Biotechnology, Jiangnan University,
            1800 Lihu Road, Wuxi, Jiangsu 214122, China
  REMARK    Annotation update by submitter
REFERENCE   3  (bases 1 to 4009619)
  AUTHORS   Meng,D., Li,J., Huang,L., Zhai,X.L., Tian,P.Q., Guan,B.Z., Cai,J.Y.
            and Liao,R.X.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-SEP-2018) Key Laboratory of Industrial Biotechnology,
            Ministry of Education, School of Biotechnology, Jiangnan University,
            1800 Lihu Road, Wuxi, Jiangsu 214122, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 256.0x
            Sequencing Technology             :: PacBio; Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003868675.1-RS_2024_09_27
            Annotation Date                   :: 09/27/2024 03:33:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,115
            CDSs (total)                      :: 3,997
            Genes (coding)                    :: 3,879
            CDSs (with protein)               :: 3,879
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 118
            CDSs (without protein)            :: 118
            Pseudo Genes (ambiguous residues) :: 0 of 118
            Pseudo Genes (frameshifted)       :: 66 of 118
            Pseudo Genes (incomplete)         :: 64 of 118
            Pseudo Genes (internal stop)      :: 11 of 118
            Pseudo Genes (multiple problems)  :: 21 of 118
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:48:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 774242
            Orig. end                         :: 796840
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032146.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(722..1369)
                     /locus_tag="D2M30_RS03965"
                     /old_locus_tag="D2M30_03965"
                     /old_locus_tag="D2M30_0842"
     CDS             complement(722..1369)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007610084.1"
                     /locus_tag="D2M30_RS03965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03965"
                     /old_locus_tag="D2M30_0842"
                     /product="hypothetical protein"
                     /protein_id="WP_125122229.1"
                     /transl_table=11
                     /translation="MCAVTILSHKTISSALLLLSVMSIAPLYNGCTMSDYIFESLGFSS
                     WSEDGAHISVIPGVVLYFAALIWCAASFRRTLPAVGLFLIFLSMGVSSSISPVTEYAAF
                     SLKQFAPERKAVEYLKHRSECSHLIERKKARMSCTIYINYYGKGEQTISVTPDLSENVK
                     GVTFKSKTFTVKPRSKTIIKTRFTGFYKGKAASDNGWSSEPDLKVASLHTAE"
     gene            complement(1433..2392)
                     /gene="corA"
                     /locus_tag="D2M30_RS03970"
                     /old_locus_tag="D2M30_03970"
                     /old_locus_tag="D2M30_0843"
     CDS             complement(1433..2392)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015087 - cobalt ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006824 - cobalt ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /function="Mg2+ and Co2+ transporters"
                     /gene="corA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388681.1"
                     /locus_tag="D2M30_RS03970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03970"
                     /old_locus_tag="D2M30_0843"
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="WP_013351400.1"
                     /transl_table=11
                     /translation="MIHITAITTHNEILDNIPLSRTEQPDIAWYWIDFFGAEMHETELL
                     RDYFHFHPLAIEDCFQHMQRPKIDHYDGYRFYVLHALNPDTLEMEEVDIFQSDRFIVSF
                     HLHESPGISRVRERFFASPGLAKKGPGHITYMIMDQLVDEYFPVLYKIEDRLNEIEDSR
                     THKSYGTLMNEVFELRTDLLNLRRTIIPMRDLMYRILSLDHVKESRETKAYFSDIYDHL
                     LKLAELIESNRDMTSDLRDSYVTLNSNRMNAIMMTLTIVSTIFIPLTFIAGVYGMNFDN
                     MPELHWKYGYFIVLGVMAALVAAMLFWFARKGWFNIFK"
     misc_feature    2457..2470
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.23"
                     /tool="antismash"
     gene            2499..3362
                     /locus_tag="D2M30_RS03975"
                     /old_locus_tag="D2M30_03975"
                     /old_locus_tag="D2M30_0844"
     CDS             2499..3362
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388682.1"
                     /locus_tag="D2M30_RS03975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03975"
                     /old_locus_tag="D2M30_0844"
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="WP_125123591.1"
                     /transl_table=11
                     /translation="MWEETVSVTPPYHFDKVLERLSLDPLNAVDLTARSIKVPLRTRDG
                     KLSVITVQAKGTAIDPVFLVSGETDREEMIERIKHIFQWEQPLQPVLDHFSKTNLSALF
                     EEHAGTPLVLEYDVYNCLMKCIIHQQLNLSFAFTLTERFVHAFGEQKDGVWCYPEPKTI
                     AALEYQDLRELQFSMRKAEYAIDLSRMIADGALNLAELPHLSDEDIMKKLITIRGIGPW
                     TVQNVLMFGLGRPNLFPLADIGLQNAVKRRFALEDKPSKDVMLQVSREWAPYLSYASLY
                     LWRSIE"
     misc_feature    complement(3523..3538)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.33"
                     /tool="antismash"
     gene            3534..4934
                     /gene="rlmD"
                     /locus_tag="D2M30_RS03980"
                     /old_locus_tag="D2M30_03980"
                     /old_locus_tag="D2M30_0846"
     CDS             3534..4934
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388683.1"
                     /locus_tag="D2M30_RS03980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03980"
                     /old_locus_tag="D2M30_0846"
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="WP_125122230.1"
                     /transl_table=11
                     /translation="MNQHQKKAPAELKIGQTFPLTIKRLGINGEGVGYFKKKVVFVPGA
                     LPGEEVVAEATNVQPKFSEARVKKIRKPSEHRVTPPCPVYEQCGGCQLQHLAYSQQLRE
                     KRDIVIQSLERHTRFNVEEMNIKETIGMDNPWNYRNKSQFQVGRSQSGSIIAGLYGLDS
                     HKIVPIKECIVQHPATNKTTGIVRRILEKHNVSVYNERTKKGDVRTIVTRVGFETGEVQ
                     VVLVTAKETLPNKDEIVKAIQNRLPEVKSIIQNINGARTSVIFGDKTKALAGSHAIQEV
                     LGDVSFELSARAFFQLNPEQTVKLYDEVKKAAQLTGKEKVVDAYCGVGTIGMWVSSEAK
                     EIRGMDVIKESIDDAKKNAKKHGIKNAAYVTGTAEHWLPKWTKEGFRPDVVIVDPPRTG
                     CDGTFLDTIKKVKPKRFVYVSCNPSTLAKDLQALSKDYRVEYIQPVDMFPQTAHVEAVA
                     KLVLKSSN"
     gene            complement(6366..7748)
                     /locus_tag="D2M30_RS03990"
                     /old_locus_tag="D2M30_03990"
                     /old_locus_tag="D2M30_0848"
     CDS             complement(6366..7748)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469907.1"
                     /locus_tag="D2M30_RS03990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03990"
                     /old_locus_tag="D2M30_0848"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_125122231.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 8.2e-43, bitscore:
                     144.6, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLRRISIVFIFVIVSSLQPVSSRAEESNHEESIIINLDSKISE
                     STINKVQEKYSNIETNYIKELDLLVINNIKPSQFSAIKDIAKEKLDANEIIEDKEISLP
                     EKSKQIPAKVAPSSQFTEDNDTLYDSWLWNIKQVTNDYRSYQINKGSHNTKVGIIDSGI
                     DFNHPDLKKNIVDTGESFVPVEDNTQDFYGHGTSVAGIIAANGDVKGVGPNLGLVPYKV
                     FDKDGKSKRSWVISAIVKATEDDMDVINLSLSTFLSKKDKDDRETIKLFEKAFKFARKH
                     NTLIVAAAGNHGYDISNSKKLAQQLGKPKDNILHLPGGVNDVITVSATTAQNTKASYSN
                     YGKNISIAAPGGDLDTNKIDLYSLVWTTSPVNIPQTPLSKSLGFQKGYEPTLGTSVAAP
                     IVTATAALLKTEYYEKYGEEMPNRKVEENLYQNTDHVENLDKNEVGSGIVNAYESLLNI
                     ER"
     misc_feature    8046..8055
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    complement(8196..8210)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.9"
                     /tool="antismash"
     gene            8204..9973
                     /locus_tag="D2M30_RS03995"
                     /old_locus_tag="D2M30_03995"
                     /old_locus_tag="D2M30_0849"
     CDS             8204..9973
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469908.1"
                     /locus_tag="D2M30_RS03995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_03995"
                     /old_locus_tag="D2M30_0849"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_260434496.1"
                     /transl_table=11
                     /translation="MTNPNFKSKEFFFLLSKTRPNIRLFILAIFLSGLSAIASTLVPHY
                     LKSLIDYYNIHEKINLWDLLGLLGIFLSSGVIGAVGSYMLSVVGYNVVANLRNLLWEKI
                     VILPVEFYDKNRSADIASRFVNDTTVIYNLVSNSFSQFINAILIVLFCGFWLFYYDWQL
                     TLVIIVAIPVYLLIFIPLGRILSKLSKMTQSLTGELNVRAVETISAIRLVKSSTAEKLQ
                     VEKGKEDVEALRSIGLKQTKWMVILNPIINLMMMLIIISIIGFGGVKLANGSLSPGTFI
                     AFLTLMFYIMGPLNNFGLFFTQIQKTIGATERISQLIYEQGEDQHKGKELAETNKDLVI
                     ENLSFCYSNEDKAFSLKNINLIIKRGSVNALVGPSGSGKTTIISILERYYKPNSGNIYF
                     GDENIELFSLKSWRSQIGYVAQNHDLISGTIRDNLIFGLENPPNEKRIVEACKKAYAWQ
                     FISELPNSLETNIGEKGLNLSGGQRQRIAIARMFLKNPNIIFLDEATASLDSHSERIVN
                     EAMKKLMKDRTAIIIAHRLSTIINADNIIFMENGEITGQGNHWELKNSHKLYHQFCEQQ
                     FKEDSTDPLVLTN"
     gene            10001..12598
                     /gene="lanKC"
                     /locus_tag="D2M30_RS04000"
                     /old_locus_tag="D2M30_04000"
                     /old_locus_tag="D2M30_0850"
     CDS             10001..12598
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013351405.1"
                     /locus_tag="D2M30_RS04000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04000"
                     /old_locus_tag="D2M30_0850"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_125122232.1"
                     /sec_met_domain="micKC (E-value: 5.2e-144, bitscore: 479.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 9.7e-17, bitscore: 59.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.7e-08, bitscore:
                     30.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLVYFQHMSEDSKYYIEKSPNAETDPYEVHNIPNYYTVSTEY
                     KSPWKFYNNPNHTLKEQGWKIHVSATMNNAQDILEVVSQIIFKHQIPFKHIKDKQSLFN
                     MNSKHGNRTSSGKFIAIYPSSNNMFFRLLNELYEELKHYENGPYILNDKSWKDSNIYYR
                     YGAFKNIYNERGELCIKDENGNLIPDNRQPYYKIPEFVSDFDQYLDSKNNLLDTQDVSN
                     FNDYEFQGVLRFNNGGGIYTGIRKSDGKKVVIKEGRPKVGLDGQFNDAIDRLNIEYEAL
                     NKLTDVEGVVNVLDYFKAWKHVFLVEEFVEGVTLQTWCAINYPFNVENDKNEYISKVKK
                     IINSLVKTIKQVHSKDVGMGDLQPQNIMITPESNVKIIDFEAASALSEENGALQTIGYT
                     NKKNKNHKERDWYALKKVLRFCILPIGPVADIEETIKKKHDMWIEDEFGKDVYQYVVDT
                     ENLCDKYLSDTKEKIFKNSYDSKIQKEMDMSKVIKGLRNSIESNILPNSSLIHGDVRQF
                     VMPSGKLNVLTGGTGAALALYRSGNVSKEVWDWIENVLLKKLNVLNDDVGLFTGRAGIA
                     AILYELGYIEQAMDLFNNLSYEDMKDISLRSGLSGIGLSLISLYMEENNDDFLVTSEKI
                     ADQIENRIIEDDKLSVTDFAAVPIGLIDGWSGISLFYAALYSVTKNEKYYLKSKEYIER
                     DLKHCKVDEETNTLQTYDDQNPRLLPYLSGGSIGIGIAIWYLNYVKNNNLFREELEQII
                     NLNKVRIAYSGGLFDGIGSFLLIPSMTKEKNETSQHIELALRKLELFLIRKDDQVLFPG
                     NFSFRLADDYYSGSAGIILGINSIQFSNPLYWLPIIKIDSFLRKTKKELLLNN"
     gene            12690..12809
                     /locus_tag="D2M30_RS21150"
     CDS             12690..12809
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="D2M30_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_221623805.1"
                     /transl_table=11
                     /translation="MKEVLVLQQFDEQSEVEPTAWTVTLTTISVTLSTLSNHC"
     gene            12861..12989
                     /locus_tag="D2M30_RS20755"
     CDS             12861..12989
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469909.1"
                     /locus_tag="D2M30_RS20755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_014469909.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGTEVEASKGKGGLLTLITTIVGSSTISNNC"
     CDS_motif       12861..12932
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="D2M30_RS20755_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12933..12989
                     /prepeptide="core"
                     /locus_tag="D2M30_RS20755_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTIVGSSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[12860:12932](+)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     gene            13016..13135
                     /locus_tag="D2M30_RS20760"
     CDS             13016..13135
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="D2M30_RS20760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_187265387.1"
                     /transl_table=11
                     /translation="MNEVLELQQLSKGSEVETAGWTLLTTLIGTSTISNSCNK"
     CDS_motif       13016..13066
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEVLELQQLSKGSEVE"
                     /locus_tag="D2M30_RS20760_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13067..13135
                     /prepeptide="core"
                     /locus_tag="D2M30_RS20760_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.30"
                     /molecular_weight="2120.4"
                     /monoisotopic_mass="2119.2"
                     /core_sequence="TAGWTLLTTLIGTSTISNSCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEVLELQQLSKGSEVE"
                     /leader_location="[13015:13066](+)"
                     /alternative_weights="2138.4"
                     /alternative_weights="2156.4"
                     /alternative_weights="2174.4"
                     /alternative_weights="2192.5"
                     /alternative_weights="2210.5"
                     /alternative_weights="2228.5"
                     /alternative_weights="2246.5"
                     /alternative_weights="2264.5"
     gene            13156..13287
                     /locus_tag="D2M30_RS20765"
     CDS             13156..13287
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="D2M30_RS20765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_014469912.1"
                     /transl_table=11
                     /translation="MRDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13156..13227
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="D2M30_RS20765_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13228..13287
                     /prepeptide="core"
                     /locus_tag="D2M30_RS20765_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13155:13227](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     gene            13432..13560
                     /locus_tag="D2M30_RS20770"
     CDS             13432..13560
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469911.1"
                     /locus_tag="D2M30_RS20770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_014469911.1"
                     /transl_table=11
                     /translation="MRDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNC"
     CDS_motif       13432..13503
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="D2M30_RS20770_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13504..13560
                     /prepeptide="core"
                     /locus_tag="D2M30_RS20770_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1724.0"
                     /monoisotopic_mass="1723.0"
                     /core_sequence="LLTLITTVVGTSTISNNC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13431:13503](+)"
                     /alternative_weights="1742.0"
                     /alternative_weights="1760.0"
                     /alternative_weights="1778.1"
                     /alternative_weights="1796.1"
                     /alternative_weights="1814.1"
                     /alternative_weights="1832.1"
     gene            13709..13840
                     /locus_tag="D2M30_RS20775"
     CDS             13709..13840
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014469912.1"
                     /locus_tag="D2M30_RS20775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_221623806.1"
                     /transl_table=11
                     /translation="MKDVLELQQLNEGTEVEASKGKGGLLTLITTVVGTSTISNNCG"
     CDS_motif       13709..13780
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKDVLELQQLNEGTEVEASKGKGG"
                     /locus_tag="D2M30_RS20775_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13781..13840
                     /prepeptide="core"
                     /locus_tag="D2M30_RS20775_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.00"
                     /molecular_weight="1781.1"
                     /monoisotopic_mass="1780.0"
                     /core_sequence="LLTLITTVVGTSTISNNCG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKDVLELQQLNEGTEVEASKGKGG"
                     /leader_location="[13708:13780](+)"
                     /alternative_weights="1799.1"
                     /alternative_weights="1817.1"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
                     /alternative_weights="1871.2"
                     /alternative_weights="1889.2"
     gene            14095..14238
                     /locus_tag="D2M30_RS21155"
     CDS             14095..14238
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="D2M30_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_181185673.1"
                     /transl_table=11
                     /translation="MNNVLALQQLNNSAEVEPQVGPTITTITVIPTMVISLISNYCDNH
                     AS"
     gene            14302..14586
                     /locus_tag="D2M30_RS04005"
                     /old_locus_tag="D2M30_04005"
     CDS             14302..14586
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015482958.1"
                     /locus_tag="D2M30_RS04005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04005"
                     /product="YfzA family protein"
                     /protein_id="WP_125122233.1"
                     /transl_table=11
                     /translation="MDKVNKKRPLYKRSWFQTVLAFLVSQLYFNFVELTGWGPKYREMN
                     GFPANIVELDFFQKYLSFYENPWFNIVTVFLGVFTVIQIITGITKVIRN"
     misc_feature    complement(15084..15099)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            15538..16521
                     /locus_tag="D2M30_RS04010"
                     /old_locus_tag="D2M30_04010"
                     /old_locus_tag="D2M30_0852"
     CDS             15538..16521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408522.1"
                     /locus_tag="D2M30_RS04010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04010"
                     /old_locus_tag="D2M30_0852"
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="WP_088612429.1"
                     /transl_table=11
                     /translation="MIDNFWRELPRPFFVLAPMEDVTDVVFRHVVSEAGRPDVFFTEFT
                     NSESYCHPDGRDSVRGRLTFTEDEQPMVAHIWGDKPENFRQMSIGMAELGFKGLDINMG
                     CPVPNVAGNGKGSGLICRPEVAAELIQAAKAGGLPVSVKTRLGYTDVDEWRGWLTHVLK
                     QDIANLSIHLRTRAEMSKVDAHWELIPEIKKLRDEIAPDTLLTINGDIPDRETGLKLAE
                     QYGVDGIMIGRGIFTNPFAFEKEPREHSSKELLDLLRLHLDLHDKYSKLEARPYKPLPR
                     FFKIYLRGFRGASELRNQCMNTKSTDEVRALLDDFERKYLDGMEQQ"
     gene            16708..17160
                     /locus_tag="D2M30_RS04015"
                     /old_locus_tag="D2M30_04015"
                     /old_locus_tag="D2M30_0854"
     CDS             16708..17160
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388685.1"
                     /locus_tag="D2M30_RS04015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04015"
                     /old_locus_tag="D2M30_0854"
                     /product="DUF6884 domain-containing protein"
                     /protein_id="WP_125122234.1"
                     /transl_table=11
                     /translation="MKRLCIIPCGKKKIWDIHPDTGPIRAEDAYLSPFHQACEWYAKAF
                     FDEWVILSAKHGFLRPDDIVPENYDVTFGTGHPEIMTAEELRRQFYEKGFSNTKELIML
                     GGKKYRSVLNSVIGEHQHLSWPLSSYKGIGYMLQALNRAVEEKQEL"
     gene            <17174..17292
                     /locus_tag="D2M30_RS20850"
                     /pseudo=""
     CDS             <17174..17292
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388686.1"
                     /locus_tag="D2M30_RS20850"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="YVNGTIDCMQKDGDGRFGYVKYQLIFF"
     misc_feature    17477..17490
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.25"
                     /tool="antismash"
     gene            17533..18534
                     /gene="acoA"
                     /locus_tag="D2M30_RS04020"
                     /old_locus_tag="D2M30_04020"
                     /old_locus_tag="D2M30_0855"
     CDS             17533..18534
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /gene="acoA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388687.1"
                     /locus_tag="D2M30_RS04020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04020"
                     /old_locus_tag="D2M30_0855"
                     /product="acetoin:2,6-dichlorophenolindophenol
                     oxidoreductase subunit alpha"
                     /protein_id="WP_125122235.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-05, bitscore:
                     22.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELLKREGLSLTEEKALWMYQKMLEIRGFEDKVHELFAQGVLPGF
                     VHLYAGEEAVAVGVCAHLHDGDSITSTHRGHGHCIAKGCDLDGMMAEIFGKATGLCKGK
                     GGSMHIADLNKGMLGANGIVGGGFTLACGSALTAKYKQTNNVSVCFFGDGANNQGTFHE
                     GLNLAAVWNLPVVFVAENNGYGEATTFEYASACDSIADRAAAYNMPGVKVDGKDILAVY
                     QAAEEAIERARNGGGPSLIECMTYRNYGHFEGDAQTYKTKDERTEHLKEKDAIQGFKNY
                     LLKETDANKLSDIEQRVSESIEKAVSFSEDSPYPKESELLTDVYVSYEKGGM"
     gene            18536..19564
                     /gene="acoB"
                     /locus_tag="D2M30_RS04025"
                     /old_locus_tag="D2M30_04025"
                     /old_locus_tag="D2M30_0856"
     CDS             18536..19564
                     /EC_number="1.1.1.-"
                     /codon_start=1
                     /gene="acoB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_388688.1"
                     /locus_tag="D2M30_RS04025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04025"
                     /old_locus_tag="D2M30_0856"
                     /product="acetoin:2,6-dichlorophenolindophenol
                     oxidoreductase subunit beta"
                     /protein_id="WP_014469915.1"
                     /transl_table=11
                     /translation="MARVISMSDAINEAMKLAMRRDENVLLIGEDVAGGAAVDHLQDDE
                     AWGGVLGVTKGLVQEFGRSRVLDTPISEAGYMGAAMAAASTGLRPIAELMFNDFIGTCF
                     DQVINQGAKFRYMFGGKAQVPITVRTTYGAGFRAAAQHSQALYGLFTSIPGLKTVVPSN
                     PYDAKGLLLAAIEDNDPVFFFEDKTSYSMKGEVPEGYYTIPLGKADIKREGGDITLFAI
                     GKQVNTALEAAAQLSEKGIEAEVLDPRSLSPLDEEAIFTSLEKTNRLIIIDEANPRCSI
                     ATDIAAIVADKGFDLLDAPIKRITAPHTPVPFSPVLEDQYLPTSDQIVSVTLELLGEPA
                     MN"
     gene            19579..20772
                     /locus_tag="D2M30_RS04030"
                     /old_locus_tag="D2M30_04030"
                     /old_locus_tag="D2M30_0857"
     CDS             19579..20772
                     /EC_number="2.3.1.-"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007408526.1"
                     /locus_tag="D2M30_RS04030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04030"
                     /old_locus_tag="D2M30_0857"
                     /product="dihydrolipoamide acetyltransferase family
                     protein"
                     /protein_id="WP_125122236.1"
                     /transl_table=11
                     /translation="MAVKVVMPKLGMAMKQGEVSVWNKKVGDPVEKGESIASINSEKIE
                     MEVEAPESGTLLHIKVKEGEGVPPGTAICYIGENGEKVQEKEAPASENAGEPQAEPETI
                     PAPKAGKERKHRVKISPVARKMAEKAGLKIDTLNGTGPGGRIVKADVIKTMKTEAEPRS
                     SVQTVQPEGKPVSAMRKVIADRMHKSLQNSAQLTLTMKADITDLVKWQKQLADSAKKRS
                     GVKLTVTHFVSRAAVLALKQHPELNSSYQEERIITYPHVHLGMAVSLENGLVVPVIRDA
                     EKLSFLELADQISTSARRAREGNASGDDLHGSTFSITNLGGYGIEHFTPILNPPEAGIL
                     GVGASYETPAFKGDELVKSTMLPLSLTFDHRVCDGAPAADFLKTVKALLEEPAGLIL"
     gene            20788..22167
                     /gene="lpdA"
                     /locus_tag="D2M30_RS04035"
                     /old_locus_tag="D2M30_04035"
                     /old_locus_tag="D2M30_0858"
     CDS             20788..22167
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012117093.1"
                     /locus_tag="D2M30_RS04035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D2M30_04035"
                     /old_locus_tag="D2M30_0858"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_125122237.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-69, bitscore:
                     232.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLAIIGGGPAGYAAAVTAARRGAEVVLIDKGPLGGTCLNEGCIP
                     TKSLLESANVLDKIRHANTFGIELPQNITLNWARMQGRKRQIVNRLVQGIQYLMKANKI
                     RVISGTASFLSDQTLLIEGEGGEKEILEAGRILIASGSEPAELPFAPFDGDWVIDSKDV
                     LSLQQIPSSLLIVGGGVIGCEFASLFSRFKTKVTMIESADRLLPAEDEDIAAAFEDSLR
                     DSGVDIQTKAALQRIDREKQTAVWTKDGKEIEAQADHILVAIGRKPRLQELNLEQAGIL
                     YSPRGIEVNDHMQTNLPHIYACGDAVGGMQLAHAAIHEGITAASHATGKDSKANMRAVP
                     RCIYTSPEMAAVGLTETQAREKYGDVKIGECSFSANGKALIKHQHGGKMKIIAEPEFGE
                     IVGVSMIGPDVTELIGQAVMLMNGEMTADMSEHFIAAHPTLSETLQEALLNVTGLAVHS
                     V"
ORIGIN
        1 ctcggacatg atggttccgt aattttgata gacgggagag ccaaagagcg cgttggcgat
       61 ttctaaaaat tgtttttgtt ccaagccgta cttctccatc attaagaatg attcagataa
      121 cgcctccagc atagaaacga gcaagaaatt gacgctgatt ttggccgcgt tggctgtttt
      181 ggtttcttca ccggtgtcaa atacttgctg acccaggctt ttaaacagcg gttcggcctt
      241 tttcttcgct tcctgagggc cggctgtgat gatgcggagc tcggccttct cagcagcatc
      301 gggacggccg aggacgggag cggcaataaa ggactgccct ctgctcgaat gcgcagcgga
      361 aagctgttct gacagcgccg tgctgatggt gctcattgaa atatgaatgc ctttttcaga
      421 taacccggca ataatgccgt ctgccccgaa agtcacgcct gttacggctt catcgtccga
      481 cagcattgac agcacaatgt ccgcatgttc agctgcctga cggggcgttt tggcatattc
      541 ggcccctttc tccagcagat cggccgcttt ttctttcgtc cgattataga cagtcagact
      601 gtatccggct ttcatgatat tttcggcgat ggggcggccc atattgccga gtccgatgat
      661 ggcgatcttc atttgcagtc cctccaatga aatgttttcc atcattatac atgtaaaaca
      721 tttattctgc tgtgtgcagg cttgcaactt tcagatcagg ttctgaagac catccgttgt
      781 ctgatgcggc tttcccttta taaaagccgg taaaccgcgt cttgatgatt gttttcgatc
      841 ggggctttac agtgaatgtt tttgatttga atgtgacgcc ctttacgttc tcagataggt
      901 caggtgtgac agatatggtt tgttcccctt ttccataata attgatataa atcgtgcagc
      961 tcattctcgc ttttttgcgc tcaatcagat gactgcattc actgcggtgc ttcagatatt
     1021 cgacagcttt tctttcaggc gcgaactgtt ttaaggaaaa agcggcatat tcagtgacag
     1081 gactgatgct ggaagagacc cccatgctga gaaagatcag aaacagcccc acagcgggaa
     1141 gcgtccgtct gaacgaggcg gcacaccaga ttaacgccgc aaaatatagc acgaccccgg
     1201 gaatgacgga gatatgggca ccatcttcag accaagaaga aaagccgagc gactcaaaga
     1261 tgtaatcaga catcgtacag ccgttataca gcggggcaat ggacatgaca ctgagaagca
     1321 gaagggcgga agaaatggtt ttgtgagaaa gaatggtaac ggcgcacacc tctttacgtt
     1381 tttttccaac atatcatgtt ttcacaaaaa aaagaacagc cggcagccgt tcttacttga
     1441 aaatattaaa ccagccttta cgggcgaacc aaaacagcat ggcggccaca agagcggcca
     1501 ttacgcccaa aacgataaaa tacccgtatt tccaatgaag ctcaggcatg ttatcgaaat
     1561 tcataccgta aactcccgcg atgaacgtga gcggaataaa aatggtcgag acgatggtta
     1621 acgtcatcat gatggcgttc atccggtttg aattcagcgt cacatagctg tctcgcagat
     1681 ctgacgtcat atcacggttt gactcgatca gctcagccag ttttaacagg tggtcataaa
     1741 tatcgctgaa atacgctttt gtttcacggc tttcttttac atggtcaaga ctcaaaatcc
     1801 ggtacattaa atcgcgcatc ggaatgatcg tccgcctcag gttcaaaaga tcagtccgca
     1861 attcaaacac ttcattcatt aaagtgccgt aagatttatg tgttctgctg tcttcaattt
     1921 cattcagccg gtcttcaatt ttgtacagca cagggaaata ttcatcgaca agctgatcca
     1981 taatcatata cgttatgtgt ccgggccctt tttttgctaa ccccggagaa gcaaaaaacc
     2041 gttctcttac ccttgagatg ccgggcgatt cgtgcagatg gaagctgacg atgaaacggt
     2101 cggactgaaa aatgtccacc tcttccattt ccagtgtgtc cgggttcaag gcgtggagca
     2161 cataaaaacg gtagccgtca taatggtcga ttttcggccg ctgcatgtgc tgaaagcaat
     2221 cctcaatcgc gagcggatga aaatggaaat aatcccgcag cagctcggtt tcatgcatct
     2281 cggctccgaa aaaatcaatc cagtaccatg cgatgtccgg ttgttctgta cgtgataggg
     2341 ggatattatc taatatctca ttatgtgttg tgattgcggt tatatgtatc ataaacaacc
     2401 ctccgcctgc cattatatca tgcggcgtta tgaagaaaag tatacgaatt gccgccggaa
     2461 cgcttcgtga tatacttgga caaaaagggg tggagcatat gtgggaggaa acggtttcgg
     2521 tcacgccgcc gtatcatttt gataaagtgc ttgaaaggct gtcactcgat ccgctgaatg
     2581 cggtcgatct tacagcaagg tcaattaaag ttccgctcag aacacgggac ggcaaactgt
     2641 cggtcatcac ggttcaagcg aaaggcaccg ccatagatcc ggttttcctc gtcagcggag
     2701 aaacggaccg cgaggagatg attgaacgga tcaaacacat ttttcagtgg gagcagccgc
     2761 ttcagcctgt gcttgatcat ttttcaaaaa caaatctgtc tgcgcttttt gaagagcatg
     2821 cgggaacccc gctcgtgctg gaatacgatg tgtacaattg tctcatgaaa tgcatcatcc
     2881 accagcagct caacctgtcc ttcgctttta ccttaacgga acggttcgtc catgccttcg
     2941 gcgaacaaaa agacggcgtc tggtgctacc ccgagccgaa aacgattgca gcgcttgagt
     3001 atcaggactt gcgggagctt cagttcagca tgagaaaagc ggaatatgcg attgaccttt
     3061 cacggatgat tgcagacgga gcgctcaatc tggcagaact tccccattta tcggatgaag
     3121 acattatgaa aaagctgatc accatcagag gcatcgggcc atggaccgtc caaaacgtcc
     3181 tcatgttcgg ccttggccgc ccgaacctgt ttcctttggc agatatcggc ctgcaaaacg
     3241 ccgtcaaacg ccgcttcgcc cttgaggata aaccgtcaaa agacgtgatg cttcaagtaa
     3301 gcagggaatg ggcgccttat ttaagctacg catccttgta tttgtggaga agtattgaat
     3361 aaaaacaaga tggcttacca atggcatctg atcgcttccg agtatttttg gaaacttccg
     3421 gtgaaaaaca tgaaggaacc gccggctgca tgttatactg aaaaaatgtg atatttcaaa
     3481 tcagccgttt tcccatgagg atggctttat tatagaaacg gagagaataa aacgtgaatc
     3541 aacatcaaaa aaaggcgcct gccgaattga aaatcggaca gacatttccg ctgaccatca
     3601 aacgcctcgg cattaatgga gagggcgtcg gctattttaa gaaaaaggtt gtcttcgttc
     3661 ccggcgctct gcccggcgaa gaagtcgttg ccgaagcaac aaacgttcag ccgaaatttt
     3721 cagaagcacg cgtcaaaaaa atccgcaagc cgtctgaaca ccgcgtcacg ccgccttgtc
     3781 cggtatacga acaatgcggc ggctgtcagc ttcagcatct ggcctacagc cagcagcttc
     3841 gcgaaaaacg cgatatcgtc attcagtctc tggaacgtca tacgagattc aatgttgaag
     3901 aaatgaacat taaagaaacc atcggaatgg acaacccgtg gaattaccgg aacaaaagcc
     3961 agtttcaagt cggacgctcg caaagcggca gcatcattgc cggcttatac ggacttgatt
     4021 cccataaaat cgttccgatt aaggaatgca ttgtccagca tccggcgacg aacaaaacaa
     4081 cgggtattgt ccgccgcata ttggaaaaac acaacgtatc tgtttataac gaacggacca
     4141 aaaaaggtga tgtccgcacc atcgtgacga gagtcggttt tgaaacaggc gaagtgcagg
     4201 tcgtgcttgt cacggcgaaa gagacacttc cgaataaaga cgagatcgtc aaagccattc
     4261 agaaccgtct gcccgaagta aaatcgatta ttcaaaacat caacggcgcg cgcacatccg
     4321 tcattttcgg cgacaaaaca aaagcgctgg ccggaagcca tgccattcaa gaggtgctcg
     4381 gtgacgtgtc atttgaattg agcgcacgcg ctttcttcca gctcaaccct gagcagacgg
     4441 tcaagctgta tgacgaagtg aaaaaagcgg cacagctgac cggaaaagaa aaagtcgttg
     4501 acgcatattg cggcgtcggt acgatcggca tgtgggtctc aagcgaagcg aaagagatcc
     4561 gcggcatgga cgtcattaaa gaatcaattg acgatgcgaa gaagaacgcc aaaaaacacg
     4621 gcatcaaaaa cgcggcatat gtcacaggaa cagctgaaca ctggctcccg aaatggacga
     4681 aagaaggctt ccgccctgac gtggtcatcg tcgacccgcc gagaacaggc tgcgacggaa
     4741 catttttaga taccatcaaa aaagtaaagc cgaaacgctt cgtctacgta tcctgcaatc
     4801 cttccacact ggcgaaagac ttgcaggcgc tgtcgaagga ctatcgcgtc gaatatattc
     4861 agcctgtgga tatgtttccg cagacggctc atgtggaagc tgtggcgaag cttgtattga
     4921 aatcgtctaa ttaaaaaacg attcctgatc agatctggat ttcggcagaa tgaacattgc
     4981 cgatttccgg gtctttttca tagggagcct ttgccctgac tgtcttttct cagagaactt
     5041 tattttcact gacgaaaaga gctgaaaaaa cgtgcggaaa ccctcatttt ctagatcaat
     5101 tcctaaagct gtaacatgat tcaacagtaa agtatctatc atgctgctcc ataaacatat
     5161 tcttttttcc gtttggaaac ggtattacag acaaaatatg aagagcaata acgactcgtt
     5221 caagtctcgt gaatacttgt aactcctgtg aatattttgt aaactccttt tttaaagaat
     5281 aaagcccctg ttgctaacta tacgtgaata attgctcctt ataatgatct atcgcttgat
     5341 tcatacaatg ttaaagtgcc gataaggcaa tgcgtttatc cggatcagca gataaaatca
     5401 atatgatctt taattggact aggggtttga taatagtcaa caatgtaata accacttttt
     5461 ggcttagcat agacaacatg ctgctgctct agttctagta atgcctttgc atctgtccta
     5521 tgacaggtgc attttttcat gtattaataa tagttggcat cgttacattt tgcttagtta
     5581 gctaattgtt cactatgatt atgaaatgat ttgttaaggc tgaatttgaa tgataagcaa
     5641 tataaaaaga ggtctgataa ttggatttat tggagcggct tgttttagtt tacattactt
     5701 gcttcaagta tcgctgtccc tattttgatg agacaattgt tggattgggg aggacagcaa
     5761 aagggctgca tacgtggatt ttgtaagtat gattgggaat ggtattacaa agtaacactg
     5821 agaataaagc cgaataaaaa gagaaaagca ctgttgattg tgaagagaga taaagagtgt
     5881 ttgggactgc taaagaagaa gtaagaatag tgggaattat tttagaagca gaaagaaaac
     5941 caactagagt gagccctgca aattttagga gaactttatg agttggttca tggtcccgta
     6001 atcaaaattt agtccgtaca caaaatcgta tagagggatt taggggaagg gaggtaagta
     6061 ggctattgaa gatagattaa agcaagggaa agaattggtc tgtttataag gtgctgttac
     6121 atgctgggtt ttgtgcgata aagaaatcaa caatagctaa agaattgaat actcaggctg
     6181 aaataaaata tgacacaagc aacttagtaa tattaagttg cttgtgaact taacttattt
     6241 agttattctc aatatcccgt aaatacaatt tatttcatct ctacttcatc atcattatcg
     6301 tctagtaatc tttttttatt aatcaaagta tttttagtga aagttcgaga actacttaat
     6361 atcttttatc tctcaatatt aagcaatgat tcgtaagcat ttacgatacc gctacctact
     6421 tcattcttat ctaagttttc aacgtggtct gtgttctgat ataagttttc ttcaacctta
     6481 cgatttggca tttcctctcc atatttttcg tagtattctg tctttaatag ggctgctgta
     6541 gcagttacta ttggagctgc tacacttgtc cctaaagtag gttcatatcc cttttgaaag
     6601 cctagtgact tacttagcgg agtttgcggg atattgacag gggaagtagt ccataccaag
     6661 ctatatagat caatcttatt tgtatccaga tcaccacctg gggctgcaat tgagatgttt
     6721 tttccataat ttgagtaaga agcttttgta ttttgcgctg tggtggcaga tacagtaatt
     6781 acatcgttaa ctccaccagg aagatgtagg atattgtcct ttggtttacc taattgttgt
     6841 gcaagttttt ttgaatttga gatatcatat ccatggtttc cagctgctgc aacaattaaa
     6901 gtattgtgtt ttctagcgaa tttaaaagct ttttcaaaaa gttttatagt ctctctatca
     6961 tctttatctt tttttgataa aaaagtagat aaacttaaat taattacgtc catatcatct
     7021 tccgtagctt taacaattgc gcttataacc caacttcttt tagatttacc gtctttatca
     7081 aatactttat acggcactaa accaagattt ggtccaactc cttttacatc cccattagca
     7141 gcaattattc cagccacaga agttccatgc ccataaaagt cttgtgtatt atcttcaact
     7201 ggaacaaaag actctccagt atctacaata ttttttttga ggtctggatg attgaaatca
     7261 atgcctgaat cgattatccc tacttttgta ttatgagatc ctttatttat ctgataactt
     7321 cgataatcat ttgtaacttg cttgatattc cataaccaac tgtcataaag agtgtcatta
     7381 tcttccgtga attgtgatga aggtgccact ttagcaggaa tctgtttact tttttcagga
     7441 agagaaattt ctttatcctc aataatttca tttgcgtcta atttttcttt agcaatatct
     7501 ttgattgctg agaattggct tggttttata ttatttatta ccaataaatc tagttcttta
     7561 atataatttg tttctatatt tgaatacttt tcctgaacct tgtttattgt cgattcacta
     7621 atttttgagt cgaggttaat tatgatagat tcttcatgat ttgattcttc agcacgagag
     7681 ctaacaggtt gtaaactgga tacaattaca aatatgaaaa ctatcgaaat tcttcttaaa
     7741 ttcttcattt ttttatactc ctttctcttt atacatttca ttatacgatt gtatataatc
     7801 caccctccta ttccaaaaaa tgaaatataa gtatatttaa ttcaatttta taaaatataa
     7861 gtaaatcagt caatgcatat ttttctaatt agaagtgatt atccccgaaa acgtcccttt
     7921 agtatgatta atttaaattt ctttttattc ttttatacta cgcctatggt tttgtgggca
     7981 gaaatattaa gagtgaatat acatttcgta atatacaaaa gtagaataat ttataactaa
     8041 agacctgttt ttttataatt tgtaaaatta tatattgact tacagttatt gagtgtgaaa
     8101 tattgtttat aggaaaatca ggaaagatat ggcgtatgtc atttcaagag tcattcgata
     8161 taaaaagttg agacattgga attaaacgaa agaggtgaaa atgatgacca accctaattt
     8221 taaatcgaaa gagtttttct tcttactgag taaaaccaga ccgaatataa gattatttat
     8281 attggcaata tttttaagtg gattaagcgc aatagcttct accttagtgc ctcattattt
     8341 aaaaagtcta atagactact acaatattca tgaaaagatc aatttgtggg acctattagg
     8401 actgctaggg atatttttaa gcagcggagt aattggggca gttggtagtt atatgttaag
     8461 tgtagtagga tataatgttg tcgcaaatct cagaaattta ttatgggaaa agatagttat
     8521 actgcctgta gaattttacg ataagaatcg ttctgcggat atagcaagta gatttgttaa
     8581 tgatactacg gtgatttaca acttagtaag taactctttt tcgcaattta tcaatgctat
     8641 attaatagtg cttttttgtg gattttggtt gttttactat gattggcaat tgacactagt
     8701 gattatcgta gcaattccag tttatttatt aatttttata cctttaggaa gaattttatc
     8761 taaattatct aaaatgacgc aaagcttaac aggtgaatta aatgtaagag ctgttgaaac
     8821 aatatctgca ataagactgg ttaaatcttc aactgcagaa aaattacaag tagaaaaagg
     8881 aaaagaagat gttgaagctt taagaagcat aggcctaaaa cagacaaaat ggatggttat
     8941 tttaaaccct atcattaatt taatgatgat gcttatcatt attagcataa ttggattcgg
     9001 aggggttaaa ttagccaatg gaagtttatc gccaggaacg tttatagcat ttctgacact
     9061 tatgttctat atcatgggtc cacttaataa ctttgggcta ttctttactc aaatacaaaa
     9121 gacaataggt gcaacagaaa gaatttctca attgatatat gagcaaggag aagatcagca
     9181 taaaggaaaa gaattagcgg aaaccaataa agatttagtg attgaaaatt tatcattttg
     9241 ctacagtaat gaggataaag cattttcctt gaaaaatatt aatttaataa taaaaagagg
     9301 aagtgttaat gccttagtag gtcctagtgg tagtggtaaa accacaatca tctctattct
     9361 ggagagatac tacaagccca acagcggaaa tatttatttt ggtgacgaga atattgagtt
     9421 attttcatta aaatcatggc gtagccaaat aggatatgta gcacagaatc atgatttaat
     9481 aagcggtact attagagaca atctcatctt tggtttagaa aatcccccaa atgaaaaaag
     9541 aatagtagaa gcatgtaaga aggcatatgc atggcaattt ataagtgaat tgcctaacag
     9601 tttagaaact aatattggag aaaaaggtct gaacttatca ggaggacaac gacaaagaat
     9661 tgctattgcg agaatgtttc tgaagaatcc aaatataatc tttttagatg aagcaactgc
     9721 aagtcttgac agtcattctg aacgaattgt gaacgaagca atgaagaagc ttatgaagga
     9781 tagaaccgct attataatag cacataggtt atccaccatt ataaatgctg acaatatcat
     9841 ttttatggaa aacggtgaga tcacaggtca agggaatcat tgggagttaa agaatagtca
     9901 taaattgtat catcaattct gtgagcagca gtttaaagaa gatagtaccg atccattagt
     9961 attaaccaat taagagcggc ttaagagagg cgaaaacaaa atggacaaaa aattagttta
    10021 tttccaacac atgagtgaag attcaaaata ctatatagag aaaagcccaa atgcagagac
    10081 tgatccatat gaagtacata atataccaaa ttactatact gttagtacag aatacaaatc
    10141 accatggaag ttttataata atccaaatca taccctcaaa gaacaaggct ggaaaataca
    10201 cgtaagtgca acaatgaata atgctcagga tatattagaa gttgtgagtc aaattatatt
    10261 taaacatcag ataccattta aacatattaa agataaacaa tctctattta atatgaattc
    10321 gaagcatggt aatcgaactt catctggaaa atttatcgct atctatcctt cctctaataa
    10381 catgttcttc aggttattga atgaacttta tgaagaatta aaacattatg agaatggacc
    10441 atacatacta aatgataaat cgtggaagga cagcaatata tattaccgat atggtgcgtt
    10501 taagaatatt tacaatgaaa gaggagaact ttgtattaaa gacgaaaatg gaaacctaat
    10561 tccggataat agacagccgt attataaaat acctgaattc gtaagtgatt ttgatcagta
    10621 tttagattcc aagaataact tattagatac tcaagatgta agtaatttta atgattatga
    10681 gttccaagga gtccttaggt ttaataatgg tggcggtata tatactggaa taaggaaatc
    10741 ggatggaaaa aaagtagtaa tcaaagaagg aagacctaaa gtagggttag atggtcaatt
    10801 taatgatgcg attgatagat tgaatataga atacgaagca ttaaataaac ttacagatgt
    10861 tgaaggtgtt gttaatgtac ttgattactt taaagcatgg aaacatgtat ttttagttga
    10921 agagtttgta gaaggtgtaa ctcttcaaac ctggtgtgca atcaattatc cgttcaacgt
    10981 tgaaaatgat aaaaatgaat acattagtaa ggtgaaaaaa ataattaata gcttggtcaa
    11041 aacaattaaa caagtgcata gtaaagatgt tggtatggga gatttacaac cccaaaatat
    11101 aatgataacc cccgaatcaa atgttaagat tattgatttt gaggctgcta gtgctctttc
    11161 tgaagaaaac ggagcgttgc aaacaattgg ctacacaaat aagaaaaata agaatcataa
    11221 agagcgtgat tggtatgcac taaagaaagt tttaagattt tgtattctgc caataggtcc
    11281 ggttgctgat atagaagaaa ccattaaaaa gaaacatgat atgtggatag aggacgagtt
    11341 tggcaaagat gtctatcaat atgttgtaga tacagaaaat ctatgtgaca aatacttatc
    11401 tgacaccaaa gaaaagatat tcaagaatag ttatgacagt aaaatacaaa aagaaatgga
    11461 catgtcaaaa gtaataaaag gattgagaaa cagtatagag agtaatattt tgcccaacag
    11521 ctcgctaatt catggcgatg tacggcaatt tgtaatgcca tctggaaagt taaatgtact
    11581 aactggggga actggagctg cattggcatt gtacagatct ggaaacgtca gcaaggaagt
    11641 ttgggattgg attgaaaatg ttttacttaa aaaattgaat gttcttaatg atgatgttgg
    11701 gttatttaca ggacgagctg gtatcgcagc aatattgtat gaattgggat acatagagca
    11761 agctatggac ttattcaata atctgtcata tgaagatatg aaagatattt cattaaggtc
    11821 aggattgtcg ggaataggtc tttcattaat tagcttatac atggaagaaa ataatgatga
    11881 ttttttggtt acttctgaaa aaattgctga tcagatagaa aataggatta ttgaagatga
    11941 taaattatca gtgactgatt ttgcagcagt acctataggt ttgattgatg gttggtcagg
    12001 gatatcttta ttctatgcgg cattatattc agttactaag aatgaaaaat attatttaaa
    12061 atcaaaagaa tatattgagc gagatttaaa acattgtaag gtagatgaag agacgaatac
    12121 tttgcaaaca tatgatgatc aaaaccctcg attattaccc tatttatctg ggggatcaat
    12181 cggaatagga attgctattt ggtatttaaa ttatgtaaaa aataataatt tatttagaga
    12241 agaattagag caaataatca atttaaataa agtaaggatc gcatatagcg gtggattgtt
    12301 tgatgggatc ggtagtttct tgttaatccc gtcaatgact aaggaaaaaa atgaaaccag
    12361 tcagcatatt gagctggcat tgagaaaact agaattgttt cttatccgca aagatgatca
    12421 agtattattc cctggaaact tcagttttcg tttagcagat gattactact ccggcagtgc
    12481 tggcataata ttgggcataa actctatcca gttttcaaat ccgttatatt ggttgccaat
    12541 aataaaaatt gatagtttct taagaaagac aaaaaaagaa ttgttattaa acaattaaaa
    12601 ctctaacact tatattcgat gataatcatt gaagattaga attaaagcag ttaatataca
    12661 gaacttatga agggaggtga gaaaagaaaa tgaaagaggt gctggtactt caacaatttg
    12721 atgaacaatc tgaagtggag cctacggcat ggactgttac tctaacaact atttcagtta
    12781 cattatctac ccttagtaat cattgctaat gagagagaag gataatctaa gaaagagtac
    12841 ttgaaaggag gtgaaaccaa atgaaagatg tattggaact tcaacaactg aatgaaggaa
    12901 ctgaagtaga agcatcaaaa ggcaaaggtg gcttacttac actaatcaca acgatagttg
    12961 gctcatctac tattagcaac aactgttaag atatttaaga ggagtggatg aacaaatgaa
    13021 tgaagtacta gagttgcaac aattgagtaa aggttcagaa gtagaaacag ctgggtggac
    13081 acttctaaca acactcatcg gtacatctac tattagcaat agctgtaata aataataaaa
    13141 aggaggtgaa attgaatgag agatgtattg gaacttcaac aactgaatga aggaactgaa
    13201 gtagaagcat caaaaggcaa aggcggctta cttacactaa tcacaacagt agttggcaca
    13261 tctactatta gcaacaactg tggataaaag accaaacata acaaaaaaag attttctgcg
    13321 tacttctagt gctgaagtag aaacagctgg gtgggcactt ctgacaacgc tcatcgatac
    13381 atctactatt agcaatagct gtaataaata ataaaaagga ggtgaaattg aatgagagat
    13441 gtattggaac ttcaacaact aaatgaagga actgaagtag aagcttcaaa aggcaaaggc
    13501 ggcttactta cactaatcac aacggtagtt ggcacatcta ctattagcaa caactgctaa
    13561 taaaagacta aacataacaa aaaaagattt tctgcgtatt tctagtgctg aagtagaaac
    13621 agctgggtgg acacttcttg acaacactca tcgatacatc tactattagc aatagttgta
    13681 ataaataata aaaaggaggt gaaaccaaat gaaagatgta ttggaacttc aacaactgaa
    13741 tgaaggaact gaagtagaag cttcaaaagg caaaggtggc ttacttacac taatcacaac
    13801 ggtagttggc acatctacta ttagcaataa ctgcggataa aagaccaaac acactaaaaa
    13861 agtacgcttg gtcttcatac attatatgaa agcctaaaca ggaaaaggac cccaatcctt
    13921 ttcctgtttc taaaaaagga ataaatttag ttttcatata aattcttatc actatcccat
    13981 acttcttatt tattgtcaat ggaaaatgaa tgaagtgggt gacttagttc tttatttata
    14041 tgtaagacta aattcaaatg ttaaatttat caaatgaaga atggaggatt aattatgaat
    14101 aacgtattag cattacaaca attaaataat agtgccgagg tggaaccgca agtgggacca
    14161 acgataacaa ctattacagt aatacctaca atggttatat ccttaataag taattattgc
    14221 gacaatcatg cttcataata taatgatttt agattgacac ttggctaaaa aagtattgca
    14281 gaaaaggaaa ctgataatta aatggataaa gtaaacaaaa aacgaccgtt atataaaaga
    14341 agttggtttc aaacggtttt ggcattttta gtttcacagc tttattttaa ttttgtagaa
    14401 ttaacgggat ggggtcctaa gtatagagaa atgaatggat tcccagcaaa catagttgaa
    14461 ctggatttct ttcaaaaata tctttcattc tatgaaaatc catggtttaa tattgtcact
    14521 gttttcttag gggttttcac tgttatacaa ataatcacag gtataacaaa ggttattcga
    14581 aattaaagca ataacttctg atgccttatt taattatgaa agaaaatgaa cactttctta
    14641 ttaatcttat gaatgaagac tgcgacactt agtcagcagt ctattttatt ggttctggat
    14701 caggattacc gaatcgtaac cattgaaagc caatcgaccc ttagtacata tactgtatag
    14761 gccagaaaaa agcaatcttt gtcaggttgt tgcttgttgc gttggttatt tctaaaccat
    14821 aagccaaatc ccaaatgatc cagattgaag ttcttgaatt cttttaagtt cgagtttatt
    14881 ttctcttccc atctcatcct ctttactcca tgtgattcac aagcggcaag ttagggcttt
    14941 ttctttttac attctcttga gtatcagata tactacccca aactcaattt gcttaatcaa
    15001 atagctcttg aaattagttt ttccgcaaac gatattgaga tacggatatg gtgcagtgtt
    15061 aaatattttc tcttcgataa caggataatt attttgaatt ggtaataggg agaactcata
    15121 tgatattcta tttgggttgg aatacttttt atccaaaaag tttaaaagta aggctgctaa
    15181 gaaagaggaa gatcagcgct agtattaata aaccacaata taaataaaaa aatacgtgta
    15241 gataatcatc acactttttt cgctctcgaa ctattataaa gttaaggagt tgactgagtt
    15301 tatagtgaca ctctattaca ttaactcaat gaaggtgttc tatcagatct gttctatttc
    15361 agttcagttt gctttttcac tttttaacgt gtaaaaagtg aaatgttcaa aatttactat
    15421 cgtttgataa gaaatgcttt cgcgtgctat aagtgtaaaa ggaaagcatg gtcagttttt
    15481 ttaattttgg aatacatgat gttgccgtat tccctaatga aaggatatga atttattatg
    15541 atagataatt tctggcgtga attgccacgg ccattttttg tgctggcacc aatggaagat
    15601 gtgacggatg ttgttttccg ccatgttgtg agtgaagcag gcaggcctga tgtgtttttt
    15661 actgagttta caaactcaga aagctattgt catccggatg gaagggatag tgtccgcggc
    15721 cgtttgactt tcacggagga tgaacagccg atggttgccc acatatgggg agacaagcct
    15781 gaaaactttc gtcaaatgag cattgggatg gcggaattag ggtttaaagg tctggatatc
    15841 aatatgggct gtcccgtacc taatgtggcg gggaacggaa agggaagcgg cctgatctgc
    15901 cgtcctgaag ttgcagccga attaatacaa gcagcgaaag cgggaggact gccggtaagt
    15961 gtgaagacaa ggctcggtta cacggatgta gacgaatggc gcggctggct gacacacgta
    16021 ttgaagcagg atattgccaa tctttccatt catcttcgta ccagagcgga aatgagtaaa
    16081 gtagatgcgc attgggagct gatcccggaa atcaagaaac ttcgtgacga gatagcgcca
    16141 gatacccttt tgacgatcaa tggagacatc cctgaccggg aaaccggctt aaaacttgcc
    16201 gaacaatatg gtgttgacgg gattatgatc ggacgaggca tttttacaaa tccattcgcc
    16261 tttgaaaagg agccgagaga acatagcagt aaggaattgc ttgatctttt aaggctgcat
    16321 ctggatcttc acgataaata ttcaaaatta gaagcacgtc catacaaacc tcttcctcgc
    16381 tttttcaaga tttatctccg cggattccgg ggagccagtg aattaagaaa tcaatgcatg
    16441 aacacaaagt caacagatga agtgcgtgca ttgctcgatg actttgagag aaagtatctt
    16501 gatgggatgg agcagcagtg acataaacaa tttctcatcc ggcccggatt tcgatacgaa
    16561 ttccgggtct ttttgtgtca gcctttaccc cgcctgcacc ctgattacag aaatcacaga
    16621 tcagctgaga agtgaccagc cccttgttat gcagaaataa gcggatagtg gtacattgat
    16681 atgaaaaaca acacaaggga gagaaacatg aaacgactat gcatcatccc ctgcggcaag
    16741 aaaaaaatat gggacatcca tccagataca gggccgataa gggcggaaga cgcttatctc
    16801 agcccgtttc atcaggcgtg cgagtggtat gcgaaagcat ttttcgatga gtgggtgatt
    16861 ttgtcggcga agcatggatt ccttcgtcct gatgatatcg tccccgaaaa ttacgatgtt
    16921 acttttggaa caggccatcc ggagatcatg acagcggagg agctgcgccg ccaattttat
    16981 gaaaagggct tttctaatac aaaagagctt atcatgcttg gcggaaaaaa ataccgaagc
    17041 gtcttaaact ccgtcatcgg agaacatcag catctcagct ggcctctgtc ctcgtacaaa
    17101 gggattggct acatgcttca agcgctgaat cgggcagttg aagaaaagca agaactgtag
    17161 cacagcaaat gcatacgtaa acggcacgat agactgtatg cagaaggacg gagacggccg
    17221 tttcggttat gtcaaatatc aattgatttt cttctgaaaa cagccattca gacaaaaggt
    17281 gcagaagaat gaagcaatta aaacatttcc gaggaaataa atacgtcgat cattgtcaaa
    17341 gaccgggtga tgtccggtct tttttgtgtg ccttaaaacg agacaggtgg atcagatcga
    17401 gacaaaatga gacacctgtc tcaaactgtc tcacagtgta aaaacaaaac cattgatttt
    17461 acgggctcaa aaagctggca cactttttgc atttattaat gtgaacccta aatagaagga
    17521 ggcgcacaaa aaatggaatt gttaaaacga gaaggcttgt cattaactga ggaaaaagcg
    17581 ctgtggatgt accaaaagat gctggaaatc aggggctttg aagacaaagt tcatgagctg
    17641 ttcgcacagg gagtgcttcc cggattcgtc catttgtatg ccggtgagga agcggtagct
    17701 gtaggggtgt gcgctcattt acatgatggc gacagtatta caagcacgca caggggacat
    17761 ggccattgta tcgccaaagg ctgtgatctg gatggcatga tggcggaaat attcgggaaa
    17821 gcgaccggac tgtgtaaagg aaagggcggt tcaatgcaca ttgccgatct caataaaggg
    17881 atgctagggg caaatggaat cgtcgggggc ggatttacgc tcgcatgcgg ctcagcgctc
    17941 accgctaaat ataaacagac taacaatgta agcgtttgct tttttggaga cggagcaaat
    18001 aaccaaggca ccttccatga agggctgaac ttagcggcag tatggaacct tcctgtcgta
    18061 tttgttgccg aaaacaacgg ctacggcgaa gcgacaacat ttgagtacgc gtcagcctgt
    18121 gattcaatcg ccgatcgggc ggctgcctat aacatgccgg gggtcaaggt ggacggaaaa
    18181 gatattttag cagtttacca ggcagccgag gaagcgatag aaagagcaag aaacggcgga
    18241 ggcccgtctt tgattgaatg tatgacctac agaaactacg gccatttcga aggagatgcc
    18301 caaacctata aaacaaagga tgaaaggact gagcatctta aagaaaagga tgcgattcaa
    18361 ggctttaaaa actatctttt aaaagaaaca gatgccaata aactgtccga catcgagcag
    18421 cgtgtcagcg aatcgattga aaaagccgtc tcgttcagtg aagacagtcc gtatccgaaa
    18481 gagtcagagc tgttgacaga cgtctacgtg tcatatgaaa aaggaggaat gtgagatggc
    18541 gagagtcata agcatgtcag acgcgatcaa tgaagcaatg aagcttgcga tgagaagaga
    18601 cgaaaatgtg cttttaatcg gtgaggatgt cgccggggga gcggctgtcg atcatttaca
    18661 agatgatgaa gcatggggcg gtgtactggg ggtcacaaag gggctcgtac aggaattcgg
    18721 acgcagccga gtgctggaca caccaatttc cgaggcgggc tacatgggtg cggctatggc
    18781 tgcggcatca accgggctga gaccgattgc ggagctgatg tttaatgatt ttatcggcac
    18841 gtgctttgac caggtgatca accaaggggc gaaattccgc tatatgttcg gcggaaaagc
    18901 gcaagtgccg attaccgtcc gcaccacata cggagcaggg ttccgggccg ctgcccagca
    18961 ttcacaggcg ctgtatggcc ttttcaccag catcccgggt ctgaagacgg ttgttccgtc
    19021 caatccgtat gatgccaaag gcctgctgct ggcggcaata gaagacaatg atccggtatt
    19081 cttttttgaa gacaaaacgt cctacagcat gaaaggcgag gtgccggaag gatattatac
    19141 aatcccgctc ggaaaagcgg atatcaaacg tgaaggcggc gacatcacgc tgtttgcaat
    19201 cggcaaacag gtcaataccg cgcttgaagc ggccgcacag ctttctgaga aaggcatcga
    19261 ggccgaggtg cttgatcccc gaagtctgtc tcctttggat gaggaagcaa ttttcacatc
    19321 gttagaaaaa acaaaccggc tgattatcat tgacgaagcc aatccgcgct gcagcatcgc
    19381 tacggatatt gctgcgattg tcgccgacaa gggctttgat ttgcttgatg cgccgattaa
    19441 acgaattaca gcgccgcata caccggtacc gttttcgcca gtgcttgaag atcaatattt
    19501 gccgacatca gatcaaattg tcagcgtcac gcttgaattg cttggcgagc cggcaatgaa
    19561 ttaaaggagg gatatagtat ggctgtaaaa gtagtgatgc cgaaattggg aatggcgatg
    19621 aagcaagggg aagtatcagt ctggaataag aaagtcggcg atccggttga aaaaggagaa
    19681 agcatcgcga gcatcaactc tgaaaaaata gaaatggaag tagaagcgcc cgaaagcggc
    19741 acgctccttc acattaaagt caaagaggga gaaggagtcc cgccgggaac ggccatctgt
    19801 tatatcgggg aaaacggtga aaaagtgcag gagaaggagg cgccggcttc agaaaatgcc
    19861 ggggaaccac aagcagaacc tgaaactatt cccgctccca aagccgggaa agaacgtaaa
    19921 caccgcgtga aaatatctcc tgtggcccga aaaatggcgg agaaggcagg attgaaaatt
    19981 gatacgctga acgggacggg gcccggtggc aggatcgtaa aagccgacgt cataaagacg
    20041 atgaagacgg aagctgaacc gcggtcttcg gttcagacgg tacagccgga gggaaaaccg
    20101 gtctcagcaa tgagaaaagt gattgcagat cgaatgcaca aaagcctgca aaacagcgcc
    20161 cagctgacac tgaccatgaa agcggacatt acggaccttg tgaaatggca gaagcagctg
    20221 gccgacagtg cgaaaaagcg gagcggtgtt aaactgacgg tcacgcattt tgtatcccgg
    20281 gccgcggtgc ttgcgctgaa acagcatcct gagctgaaca gttcttatca agaggagcgg
    20341 atcattacct atccgcatgt ccatctcggg atggcagttt ctcttgaaaa cggccttgtc
    20401 gtgccggtga tccgtgatgc ggaaaagctt tcattccttg agcttgcgga tcaaatcagc
    20461 acatctgcac gccgggcgcg ggaaggaaat gcttccggag atgatcttca cgggtcgact
    20521 ttttctataa caaatctcgg ggggtatgga attgaacatt ttaccccgat ccttaatccc
    20581 cctgaagccg gtattctcgg agtgggcgca agctatgaaa cgccggcgtt taaaggggat
    20641 gagcttgtca aaagtaccat gctgccgctg agcctcacct ttgatcacag agtatgtgac
    20701 ggcgctccgg ctgcggactt cctgaaaacg gttaaagcgc tgcttgaaga gcctgccgga
    20761 ttgattttat agagaggggt gaggagattg acactagcca ttatcggagg agggcctgcc
    20821 ggatatgcag ctgccgtgac tgccgcgcgg aggggagcag aagtcgttct gatagacaaa
    20881 gggccgctcg ggggcacgtg tctcaatgag gggtgcatcc cgacaaagtc gctgttggaa
    20941 agcgcgaatg tgcttgataa aatcaggcac gcaaatacat tcggcatcga acttccgcaa
    21001 aacattacgc tcaattgggc ccggatgcag gggcgcaaac ggcaaatcgt caaccggctc
    21061 gtgcagggca ttcaatactt aatgaaagca aataaaatta gagtcatcag cgggactgct
    21121 tcatttctct cagatcaaac attgctgatt gaaggggaag gaggcgaaaa agaaattctg
    21181 gaagccggcc ggatattgat tgcatcaggg tctgaaccgg cggagctgcc gtttgccccc
    21241 tttgacggcg attgggtgat cgacagcaaa gatgtgcttt ctttacagca aattccgtcc
    21301 tcccttctca ttgtcggcgg aggtgtgatc ggctgtgagt ttgcctcttt attcagccgt
    21361 tttaaaacga aagtgacgat gattgaatcg gctgacaggc tgctcccggc agaagacgaa
    21421 gatatcgcgg ccgcttttga agactctcta cgagacagcg gggttgatat tcagacgaaa
    21481 gctgcgctcc agcggattga cagggaaaaa caaaccgccg tgtggacaaa agacggaaaa
    21541 gaaattgagg cgcaggctga tcacattctg gtcgcaatcg gcagaaagcc gcgtttgcaa
    21601 gagctgaatc tggagcaggc cggcatcctt tattctccgc gcggcattga agtcaatgac
    21661 catatgcaga caaatttgcc gcatatatac gcatgcggcg acgcggtcgg aggcatgcag
    21721 ctggcgcatg ccgcgattca tgaaggaatc accgccgctt cgcatgccac gggaaaggac
    21781 agcaaagcca atatgcgggc ggtgccccgc tgtatttata catctccgga aatggccgct
    21841 gtcgggctga cagaaacaca ggcgagagag aaatacggag atgtaaaaat cggagaatgc
    21901 tcattttccg ctaacggcaa ggcattaatt aaacatcagc atggaggcaa aatgaaaatc
    21961 atcgccgaac cggaattcgg agaaattgtc ggggtgtcaa tgatcgggcc ggacgtgacg
    22021 gaattgatcg ggcaggcggt catgctgatg aacggcgaaa tgacggcgga tatgtcggag
    22081 cactttatcg ccgcgcatcc gactctttcg gaaacgcttc aggaagccct tctgaatgtc
    22141 accggcctcg ctgtgcattc cgtatagccg ggataccctt tctcaggact gagaaggggt
    22201 atttttcgtt gaaagcgctt tacttttccc ctacaatata tgaaaagatg gtctgaacag
    22261 gggggagcga atacaatgaa tgtcattcgg aatgatttta aaacctggaa gcgctttgtg
    22321 aaagaaggcg tgctcgatga atcccgtatt cagaaacggg tggccgcctc atggcaccgc
    22381 tgcaaaaaag ctgatgtcaa tccttatctt gaaaaggggc cgaatgtgat gccggcagat
    22441 catttagaaa ggcaggccga gaagcatgcg ttattcttag cggcctcggc accgtatgca
    22501 gaaaaaatga aaacggcgat gcgggaaatg gaaatgatgg ttctcctgat tgatgccgac
    22561 ggcgttgtcc attcagttga cggccacccg cgcaccat
//
