LOCUS       NZ_CP034118            31173 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Staphylospora marina strain SCSIO 07575 chromosome, complete genome.
ACCESSION   NZ_CP034118
VERSION     NZ_CP034118.1
KEYWORDS    RefSeq.
SOURCE      Staphylospora marina
  ORGANISM  Staphylospora marina
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Staphylospora.
REFERENCE   1  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Staphylospora marinus gen. nov., sp. nov., a novel member of the
            family Thermoactinomycetaceae, isolated from a deep-sea hydrothermal
            vent sediment in Pacific Ocean
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2018) CAS Key Laboratory of Tropical Marine
            Bio-Resources and Ecology, South China Sea Institute of Oceanology,
            No. 164 West Xin Gang Road, Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: FALCON v. 0.3.0; Celera Assembler v. 8.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1382.0x
            Sequencing Technology             :: PacBio Sequel; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003856495.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 03:57:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,772
            CDSs (total)                      :: 2,679
            Genes (coding)                    :: 2,660
            CDSs (with protein)               :: 2,660
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 6, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 4 of 19
            Pseudo Genes (incomplete)         :: 16 of 19
            Pseudo Genes (internal stop)      :: 0 of 19
            Pseudo Genes (multiple problems)  :: 1 of 19
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2487687
            Orig. end                         :: 2518860
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034118.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31173
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="9"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..31173
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31173
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:21173](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..21173
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(469..1731)
                     /locus_tag="EG886_RS12250"
     CDS             complement(469..1731)
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009710357.1"
                     /locus_tag="EG886_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="argininosuccinate synthase"
                     /protein_id="WP_124728402.1"
                     /transl_table=11
                     /translation="MQKEKVILAYSGGLDTSVAIKWLNETYGYDVIAVALDVGEGKDLD
                     FVKNKALKVGAVKSVVVDAKRWFADHFLIPALKANAMYEGKYPLVSALSRPLISQVLVE
                     VAKAEGAVAVAHGCTGKGNDQVRFDVSVTALAPHLKVVAPVREWAMSRDEEIAYAEKHG
                     IPIPVDLDNPFSIDQNLWGRSCECGELENPWTAPPEAAYEWTSSVENAPDTPDEIIISF
                     EQGVPVRLNGEAMPFDELLAALNKLAGKHGVGRIDHVENRLVGIKSREVYECPGAITLI
                     TAHRELEFLTQPRDIARFKPVIEQKWAELVYDGLWFSPLKKALDAFIDQTQKPVTGDVR
                     VKLFKGSVTVTGRTSPYSLYDEKLATYTADDEFDHQAAVGFIKLWGLPTNIYANVHMED
                     EKDETLGRALFQTDGSLGGGI"
     misc_feature    complement(1727..1740)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.02"
                     /tool="antismash"
     misc_feature    complement(1759..1772)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.17"
                     /tool="antismash"
     misc_feature    complement(1769..1782)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.61"
                     /tool="antismash"
     misc_feature    1818..1832
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            complement(1844..2947)
                     /locus_tag="EG886_RS12255"
     CDS             complement(1844..2947)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088: acyltransferase 3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /locus_tag="EG886_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase"
                     /protein_id="WP_124728403.1"
                     /transl_table=11
                     /translation="MLRKYHLLHAARGIFSLLVVVLAAHRAGLHHWDVELIPGLDDRVR
                     FGAMDFFFLLSGFVLFASYKSSIGDKRTARGFLIKRLIRIYSVYWYILIAIIPLSAFLT
                     GQKASLDSIGPSVLLIPHEDSLLSSSGLLSILLVFYLFFFLFLFLGRNAGTLVAALWFL
                     AVVIFFTQDVNLEHPVLQVLFSKYHLYFFAGAFIAHLTDKIPVKQPAWIFLIGATGTVL
                     GVLNDLYGWVPLDDMYNYGVPVSLLLFGLAAADVKTEIRLPAWIQFMGQASYSLFLVHE
                     PMLTLLFHLSGKDDWLGWADPLLLFALIIVAVILVGWLTHVLIEKPLLSFIFFRGNLQV
                     SSDSYLTKRQEFFGGAERNVAGPEAKA"
     misc_feature    3037..3050
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(3038..3051)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    complement(3199..3208)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            3427..4296
                     /locus_tag="EG886_RS12260"
     CDS             3427..4296
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013672.4"
                     /locus_tag="EG886_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_124728404.1"
                     /transl_table=11
                     /translation="MQPVRFIALPVAGLLFVLSACTPATSGQEHPSPSASSRTAERPAP
                     DVDKSGESVREHPEERIRETYRGVTPKEWGEQVRGVITRFETKEPLIALTFDACGGPRG
                     SKFDQALVDHLIREQIPATLFVNSRWIDANRDTFLRLSENPLFEIGNHGTEHRPLSVNG
                     RSVYGIRGTSDPAHAFREVWLNHEKIRNLTGREPKFFRAGTAYYDEVAVRIVHETGERV
                     AGFDVVGDGGARFSASQVKQALLSAKPGSIVILHFNQPNGETFEGLRQAIPVLKQRGFR
                     FVKLEDVL"
     gene            complement(4317..5078)
                     /locus_tag="EG886_RS12265"
     CDS             complement(4317..5078)
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008880475.1"
                     /locus_tag="EG886_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_124728405.1"
                     /transl_table=11
                     /translation="MDVTEMLTRLGIDRKETEKPGRNRLELLMHQHLLTVPFENLDIRA
                     NVPILLDLPMIYEKVVRRKRGGGCYELNGLFAWLLEKLGYRVRLLSARVFRPDGTPGPE
                     FDHLTLLVFDEQPLLVDVGFGDSARRPVPLDGSVVSDVSGDYRVMPAADPDAWVLEKRQ
                     PGEEWKPQHQFTLRPWILSDFMPMCIHHQTSPESGFTRRMVCTIATETGRITLTDEGLT
                     ITERGEKKKIPVRSLPERRAALQRWFGIRLV"
     gene            complement(5246..6493)
                     /locus_tag="EG886_RS12270"
     CDS             complement(5246..6493)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721461.1"
                     /locus_tag="EG886_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="WP_124728406.1"
                     /transl_table=11
                     /translation="MKKTGEYQRLRHEIYESLRQEGVFTWDWMYGKEYALADLCLISPE
                     FRAEIADVTERLGRIFARTMEVVQKAGDELLAELGIPEAARPAVRMSVCAEMPTLVGRF
                     DFARTPRGLKMLEFNSDTPTCLVEGFHVNGVVCGKFGVENPNHGMREHIRDAFATMVRE
                     YRRLGFASDSIVFSSLGRHEEDRGTTRYLLDASGLDGRFVPLEELSYCQGRLHARDGDD
                     WRPVDVWYRLHPIELMVKDRDKDGFPTGIRILELTVSRRLAMINPPSALISQTKALQAL
                     IWNLAESDLFFTDEERQTIRDHMLPTYLDNVFHGKRPYVSKPVFGREGGGVRLYDSTGG
                     VIAQDGGTLYWDQPMVYQELAELEWVEVETLQGTVRGKQLWGSFLIGGRASAIVSRVDQ
                     EITGNDSLFLPVGIRS"
     misc_feature    6478..6493
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.25"
                     /tool="antismash"
     gene            complement(6498..6740)
                     /locus_tag="EG886_RS12275"
     CDS             complement(6498..6740)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124728407.1"
                     /transl_table=11
                     /translation="MEKRLPFGGKTSKVVGLFAAALISLTVSGCDLDYCADDNKDRKCD
                     EDGTPVDPNDWIEEDGKRKYLKLYEDYDDDEGFGG"
     gene            complement(6967..7647)
                     /locus_tag="EG886_RS12280"
     CDS             complement(6967..7647)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016087430.1"
                     /locus_tag="EG886_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerC family protein"
                     /protein_id="WP_124728408.1"
                     /transl_table=11
                     /translation="MDFLSFEFLSALLSIIIIDLVLAGDNAIVIGLAARNLPKDKQKKV
                     IVYGTVGAIIIRAAATLAVVWLLKIPGLLLIGGLILVWIAWKLLLEEKKHDVQAADSMW
                     AAIRTIIIADAVMGLDNVLAVAGAAHGSYLLVILGLLISVPIVVWGSTVVLRLLERYPR
                     LIYVGAGVLAWTAGKMIADEKLFHDVFAQADWLKYVFAALVVAGVLLVGKWAKNRGKET
                     ANAG"
     misc_feature    7815..7824
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.81"
                     /tool="antismash"
     misc_feature    complement(7850..7864)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.72"
                     /tool="antismash"
     misc_feature    complement(7871..7883)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.4"
                     /tool="antismash"
     misc_feature    7904..7919
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    7906..7920
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.95"
                     /tool="antismash"
     misc_feature    complement(7917..7933)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            8042..8662
                     /locus_tag="EG886_RS12285"
     CDS             8042..8662
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="EG886_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_124728409.1"
                     /transl_table=11
                     /translation="MRLVCLIVVHPSPHTASETVSRWKEEIRKRLPETAPVRRHDAEEN
                     RLLWLHACCQEEVRTRLDGLDPSAASILCTDGSQDVWLSFLAVGVRGFVSFRDQKELPG
                     AIRAVNAGGLYFSRSYHERAGDILYWNHLIHRENHSLPLTPTERRIIQEIAMDRSNREI
                     AQSLRISERTVEHHVSTALRKTGAKSRVGLVIRTLKNFQINVI"
     misc_feature    8665..8679
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    complement(8670..8684)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.3"
                     /tool="antismash"
     misc_feature    8843..8857
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(8845..8856)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: strong, score: 19.87"
                     /tool="antismash"
     misc_feature    complement(8889..8900)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.98"
                     /tool="antismash"
     gene            9052..9210
                     /locus_tag="EG886_RS12290"
     CDS             9052..9210
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002195048.1"
                     /locus_tag="EG886_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_241154324.1"
                     /transl_table=11
                     /translation="MVEVKDLEITGLDIMDLSDAAALPETGASSGESSCSVASSTCGSS
                     SCCSSCW"
     gene            9255..9413
                     /locus_tag="EG886_RS12295"
     CDS             9255..9413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002169255.1"
                     /locus_tag="EG886_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_124728410.1"
                     /transl_table=11
                     /translation="MDMEIRHLEVTGLEVMELSDAAALPETGASSGITPCTYCSTCGSS
                     SCCASCQ"
     gene            9516..9665
                     /locus_tag="EG886_RS12300"
     CDS             9516..9665
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008179393.1"
                     /locus_tag="EG886_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_124728411.1"
                     /transl_table=11
                     /translation="MEIRDLEITGLEVLDLSDAAALPETGASSGSTSCSASSTCGSSSC
                     CASC"
     gene            9705..9854
                     /locus_tag="EG886_RS12305"
     CDS             9705..9854
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008179393.1"
                     /locus_tag="EG886_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiazolylpeptide-type bacteriocin"
                     /protein_id="WP_124728412.1"
                     /transl_table=11
                     /translation="MEIRDLEITGLEVLDLSDAAALPETGASSGSSSCSASSTCGSSSC
                     CGSC"
     gene            10001..12724
                     /locus_tag="EG886_RS12310"
     CDS             10001..12724
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="EG886_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_164491835.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-51, bitscore:
                     172.6, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVSGENLIRPPKRVSRRLFPHFLIRTGGLPADGLRFMRAKETVE
                     RLREMTALSRRLSEENGELIEAVEREVPQVRSDSLRNALIRFKRDLYNGRKPKVRVTEE
                     WAELTPELAQRIRLRLQNEERLVKLREEARTRFEEELLDARRHLRQTVTDPRLLAGIAL
                     TSQELHEKAVKYIETPVERQKSRLRKVETSLVKFVTRASVKTSPFSTFTAVGTGSWDER
                     AEHAPFTLPSPNHRVFTELNHANLLRVMEGLCAHPEVRVQLRYRINPTLIIDQGRVKYI
                     RRTDDSKLRPRVFKTLETPVSLDANPAIRLVLSRFGDASELSYAELIRRLTEAGQFPAE
                     QLRAFVNQLISLQVLVPVLPRHEQNPDLAGWLIRWLESLDGDIPKTARDHLIRIRELAE
                     AAPDDTPETRSRRLRDIRNEFHALRKSVGFELSDESLALLLFEDAILEEEARMNPSAWE
                     RHLDDLFAWQRLLPVLDVKFRIQSKIAAQFVEMYGENGICDRPGRFLSQVITSITDYFR
                     SMLPSNMMKDTELHNDVENVRRLNELKRELGKLIAEKLRSSEEEAFLSREEIERLTERI
                     PAQVQHRFLTNDAFVQPALADGKPLWVLNHLYVGNGTFFTRFLPWFREELTQRLREELR
                     ELVHPRTLAELSGVFGFNANLRPRLAPFELDLPMLPPARDGLGPDEVISWEDVILKYDK
                     REDRVKVVHPKHGDLAVLFAGTLIPALLPFVVNFLVTQFTCGNMPENLFLFAEEELSPD
                     ERQKIRIWPRLRVGDVVLSRKKWVIPRGHLPKREPNDSDFDWFERVHRWKEEIGFPDRI
                     FVRFIPLDDSENPFGEDREPSDASRNFDFTDWKPQWIDFQNPLTVKLLGKMIAEQPTGM
                     IAEEMLPDLEHLATDPDDHKRVNEWVIELSQVPEVE"
     gene            12729..13868
                     /locus_tag="EG886_RS12315"
     CDS             12729..13868
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="EG886_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_124728414.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.1e-39, bitscore:
                     133.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWKAVRITYYEDNKDRLLTEAIKPAVEKLQTRGLGRWFLRRHWKR
                     GPHISLVLEDTNERLETDWLPLIRETVLPWLNDHPSRKEIDPDQYLKLSETLGAWELEP
                     GPYLPLSPDNSLNVEPHDRREDVVSGARVAELLEAFRSDVAPVTLELIAESAGNRGKRL
                     EQMIGLMAVIAELYPLGGITRGHLSYRSHVEGYLHTFDTDGRLRETFRQRDRELGGRID
                     ELVRAVLAHTGEEGGVYHGPDRWLRAWAEASLRLYTEAKTLADAGELTSRTDHYREIAA
                     TIGEEAVKRWDPSGNERGLSPFHQNLQSREEGMRVLQSPEFAAYRIVVNAFYAHLPLFD
                     INPHTKHLLCELVSNATERIKGVTWQQLTGFGQGGTADA"
     misc_feature    complement(12731..12749)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.95"
                     /tool="antismash"
     gene            13861..15741
                     /locus_tag="EG886_RS12320"
     CDS             13861..15741
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124728415.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 5e-16,
                     bitscore: 55.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     1.5e-15, bitscore: 54.2, seeds: 5, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEQRPKWRRHVHFAPTENGVYFHTWNSEFALKGKGLHAWVERLA
                     LHFTGEKTLKELTDGLGDAHRRFVLQLTEELFKRGVLTDGNREEATTLSPSEKELYDDT
                     LAFLELHAEDAKKRFLRFRLHRPRVAGSGKAMFALVRSLVKMGVKSPVLPADASGDIRR
                     LAEEWAARDPAFSPVWQDPLSPGDEREAEPVDGIIFIGEWTEREHFARWSRFARERGIP
                     FLPVTIHPSGGWVGPLESPESIATWQCARDRFTDADASGEKTVTSDLLLGNIGALEWLK
                     HVTGAAESDVINHVMDLSSKRLETVRRRIHPSPLVLGSSRLVPPVSPPDSGEEPEDQGV
                     FLDKAESLTDPRFGVLLRISPGDLMQIPLPLIAVTTRIPGAGKDGIRTFVGAGETVRDA
                     TETALREALTAYARELEAVVTGNADTTEDGPVSAVWSHGRSRDEWAGSGLLRSWIRVSL
                     SRGNRGLVRLNREDLPDGKHRRYLKMLDIRYGRKPELWMFRSQTPRAVGIFLTEDGNLL
                     AEGAGRTFHEALERALPEALRRLQLAEHHPEFAPPAEAVWFPREEDPEADRTIRMDEPV
                     PDWAEWLKEAERFATQSGFRIRREPWTRDPFPAELGVWVGQVGWEGGNEP"
     aSDomain        13864..14109
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EG886_RS12320_Thiopeptide_F_RRE.1"
                     /evalue="5.40E-18"
                     /identifier="RREFam004.1"
                     /label="EG886_RS12320"
                     /locus_tag="EG886_RS12320"
                     /protein_end="83"
                     /protein_start="1"
                     /score="55.8"
                     /tool="antismash"
                     /translation="LEQRPKWRRHVHFAPTENGVYFHTWNSEFALKGKGLHAWVERLAL
                     HFTGEKTLKELTDGLGDAHRRFVLQLTEELFKRGVLT"
     aSDomain        13879..14139
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EG886_RS12320_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="1.60E-17"
                     /identifier="RREFam011.1"
                     /label="EG886_RS12320"
                     /locus_tag="EG886_RS12320"
                     /protein_end="93"
                     /protein_start="6"
                     /score="54.2"
                     /tool="antismash"
                     /translation="KWRRHVHFAPTENGVYFHTWNSEFALKGKGLHAWVERLALHFTGE
                     KTLKELTDGLGDAHRRFVLQLTEELFKRGVLTDGNREEATTL"
     gene            15738..17714
                     /locus_tag="EG886_RS12325"
     CDS             15738..17714
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="EG886_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_124728416.1"
                     /sec_met_domain="YcaO (E-value: 4e-74, bitscore: 247.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.2e-101, bitscore:
                     337.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHTVWLWAEGRLADMLAPVLEEVCEVVRVDGLPDEPGPGRPDAL
                     LLCHDARLLDREADAQDRARRWGVPFFRIHLYVDRVFAGPWVLPDEPGCVHCVEWRMSL
                     VHPQREIWHSLAKAQRMHAEAGIHRGWSPPFLDSLSLIVRDELERLLSGKPPRLKRSIY
                     VATDGMMNGRIHAFQPNPLCPRCGNLPDDTPERAVFRVRSLPKPHPRTWRLPNPNIRND
                     VLREAFYDWRTGLFPHLYRDVYSRFMPIFGAEMPLPDRKSTEIGFGRTDTFRDSELTAM
                     LEGLERYAGMVPRGKRTVHRASWNEVRDRAIHPPEWGIHHPDQRDEPGYAYVPYSDDLK
                     VNWVWGFSWKEQKPVLVPEQMVYYRLPDPPERPTNRFVYETSNGCAMGGSLEEAVFHAL
                     MEVIERDAFLVSWYNRLALDEIDVEGVHNRNILLVKDRVEANGYRLHLFDMTMESGIPA
                     VWALMINPAEDAKVKTYSAAGAHPDPEKAIMGALVEVVTSVPIYEEIMPAQRDKAERMV
                     HDPGLVQEMHDHVLLYSHPDTLPRFDFLFREKKRPRPVRELYRRWYEEEPPGDLGAELK
                     ELLDKLTRLHGDVVIIDETTPELEALGIRAVKTLVQGMLTMSFGHQYRRIVMKRVLEAP
                     VRTGRRPSPIREEEINLFPHPFP"
     gene            17731..19293
                     /locus_tag="EG886_RS12330"
     CDS             17731..19293
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_124728417.1"
                     /transl_table=11
                     /translation="MDTFEREFREMLYRQTYGRFRAHRTPDDHTPPDPLITDKPCLKRI
                     PLPTELPDLGSLDSRGPAHGDFGSVSLANRLSALLHCTLGVSRLEIGTPRPLHRPVPSP
                     RCLHACELLAALPPGSPTGEGSFRYHPVRHELEVRREERVWHELEQALGMPLHDADAVL
                     AVSAEWWRIAWMYGDFSFHLATLEAGHLRGHLLWLAEPLGFRAQWMDRFDSRALSACFG
                     LNPEAETLLSVLVLRSVCEQRPEAAERLPFRTGIPGTDTDGDGQANLLKQCPDLMRLTE
                     RTRPHPPSVGRRLDPPIASFPLAPADRPFCEPDLSFGKWRYPRREDILKRRSGGNDVLG
                     LAADGSPVSLEELSAVLGRLRDHVAVHPELVRGIRLFLWARRVEGLSPGIREVRPDGSL
                     VSLRTDGCPSLAGIGTADPRTAHLDSFPIAFLFTADYIGEYRLTGPEAMPLLQQRTGHL
                     TQWLMLHATAMGWMARPVKSFDELRAEEILNLTETGETAVYLLLVGKHRHPFLSLDMSL
                     GGV"
     gene            19297..20280
                     /locus_tag="EG886_RS12335"
     CDS             19297..20280
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="EG886_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_124728418.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-62, bitscore:
                     209.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAAHPDWLALHAFTHDPFGQDSLLLEGILPALRRLERKGAFQK
                     WFFLRYWEGGPHLRVRFFRPEEGVEASIREAAETFLKSRPPARTLTRDAYYANHRFDGE
                     PVDPDTLPWYEHGQVVRLPYFPEIDRYGGPEAMPVSEDLFHASSELAVRVMEASGSLND
                     RVARAMDIMVVTALAMEVKPEELETYFDRYARFWERFVDDPEASEKRIRASFERQKDSL
                     VHRLRLLIRLVRGEFTYELFANWLNALNRAREAYADIHRNGRLRAPFPGAPDDPAQFFR
                     AAVSGIAFSQIHMTNNRLGVPPVHEHYLGMMISLTAAAHREAEGGT"
     gene            20280..21173
                     /locus_tag="EG886_RS12340"
     CDS             20280..21173
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="EG886_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_124728419.1"
                     /sec_met_domain="PF00881 (E-value: 1.9e-18, bitscore: 64.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRKPFLTASLHHLSPEERSRMLGTHFPDPFEPALRYHESSSFHP
                     DLMSFQAPRSAYLLPDHRRLRTGEKLDLPPEESLPPLSASLGDVIHRRRSRYAFGGEVR
                     LEELAALLTGGLGITARKEVKDGAGQTYVLQLRGYPSGGALYPVETWVVMNRVTGEGAG
                     VYRFSAPDRCLWKVPDLSLRPEDIAAWTPGTDPDRNPLYSAEDFTEAAAFLLLVADFSC
                     QADKYGPRAYRLALLEAGHMAQNLLLAATALDLFAVPIAGFYDGRANQALRLDPRRQAL
                     VYLIPVGRPKEESQTP"
     gene            21170..22312
                     /locus_tag="EG886_RS12345"
     CDS             21170..22312
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /locus_tag="EG886_RS12345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_124728420.1"
                     /sec_met_domain="ThiF (E-value: 1.7e-22, bitscore: 77.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSLDSSREYIRFRPGVFPSFPASGQIELRTGPLGPPLIRLLLPE
                     GEDWVSPIFRRLDGSRPIPELLDAIPESRRADARKLLSVLVAKRWAETGDAPFKAEDPV
                     KDHLLAFRSFSNEDAERTLRKTRLLVLGAGRLGSRIAGNLTMTGFRQLTLLDPSPVSFQ
                     DRTASPLLLQAEPGTPRANALASALREMAPDAAVQAVTEADGRTLEREMAEHDLTIVAE
                     DCFHPRLLSDVNRLAVRLGKRWSMVLVNGWNLHVGPTIFPGQSGCLLCLHLETGETWVP
                     ENAPEEPAADSGEPTRSLESGFPSLVWPPHADVAAGLLATDMLHAAGIMPRRIEPGTGM
                     TLGRQLVFDLKSGQAFWRTVPRRPDCPVCGPGALSHPHEY"
     misc_feature    22330..22341
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     misc_feature    complement(22330..22345)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.55"
                     /tool="antismash"
     misc_feature    complement(22577..22591)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.83"
                     /tool="antismash"
     gene            22613..23356
                     /locus_tag="EG886_RS12350"
     CDS             22613..23356
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009709927.1"
                     /locus_tag="EG886_RS12350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124728421.1"
                     /transl_table=11
                     /translation="MTREQPVIEVRELRKTYGDVRAVDGISLEVFRGEIFGVIGANGAG
                     KTTTLEMMMGLRTPDSGTIRVLGLEVPRQSSELKQRIGIQLQQTALYDRIKVKEALDVF
                     GAYYRQRRDQKEIIDLLGLEPYLDKTVKKLSGGWQQRVALALALINDPEIIFLDEPTTG
                     LDPQARHDLWQIILSLKNEGKTILLSTHYMEEAQRHCSRVAVIRQGRLVACDTPAGLIA
                     RLPDGNGTMDDVYVQMAVGPKGESA"
     gene            23356..24096
                     /locus_tag="EG886_RS12355"
     CDS             23356..24096
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="EG886_RS12355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_124728422.1"
                     /transl_table=11
                     /translation="MKALLAHTRLEVTLLFREVIAVFFSFLLPGASFVIMGKIFGDQVY
                     STGTYFETYIPSMMGIIIFATCLFAVGLQVVIDREKGVYKRLKGTPINPFHVLVALLAK
                     GFIAIYVGVVEILVLARLVFDVSLTPHLLQFLGAVTWATLSFLGLGFLMVSVTRRMQTA
                     LAFGFICMYPMMFLSGSFFPLDMMSDFWKDVAQFNPLFHANQLMILGYKGDLFTQTGAI
                     SAAVLGGILVVGSGIGFRYFRWEP"
     gene            complement(24170..24841)
                     /locus_tag="EG886_RS12360"
     CDS             complement(24170..24841)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS12360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124728423.1"
                     /transl_table=11
                     /translation="MKRLNTSQLLKEISPYDWFSWNGEEGKPCPHRICFTMPEEQFNRK
                     INVASPLYWGFEAVNNKSADPTFTPREWIAWEQAFFDWLETAGEFLFPSGNTVVSPDLS
                     REWRVDAYLAPGWKEEHPRFEEWFGPACQAYEDLLAGARIISRGPAEWDDARAAAVESW
                     AEVRLLGQASIKGVPLLFFCGGKWVASITEYLTVQVSARDGETLRQLKEELGERLDPRF
                     L"
     gene            complement(25722..26684)
                     /gene="argF"
                     /locus_tag="EG886_RS12365"
     CDS             complement(25722..26684)
                     /EC_number="2.1.3.3"
                     /GO_function="GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /gene="argF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020619555.1"
                     /locus_tag="EG886_RS12365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ornithine carbamoyltransferase"
                     /protein_id="WP_124728424.1"
                     /transl_table=11
                     /translation="MNALLSKPALAPLKGQDFLTLEGLSPSGLQSLVELAHQMKTQRQL
                     WSIGAPLKGKTLAMIFDKPSTRTRVSFEVGMAQLGGHALNLQREELQMGRGESVEDTAK
                     VLSRYVDAILIRTFSQELVEELATHAEIPVINGLTDLYHPCQILADLLTLWEVKGTLSG
                     LKLTYVGDGNNVLHSLMHGAALAGIHLHISTPPGYEPLPEVWKQAEEMAALTGGSLHFS
                     HDPFVAVQGADAVYTDVWASMGQEEEKEKRLRDFQGYQVNETLMALAKEDAVFLHCLPA
                     YRDWEVSPGVIDGPRSVVFDQAENRLHAQKALLMALLGE"
     gene            complement(26681..27889)
                     /locus_tag="EG886_RS12370"
     CDS             complement(26681..27889)
                     /NRPS_PKS="Domain: Aminotran_3 (14-332). E-value: 9.3e-98.
                     Score: 319.3. Matches aSDomain:
                     nrpspksdomains_EG886_RS12370_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018669816.1"
                     /locus_tag="EG886_RS12370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_124728425.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-112, bitscore:
                     373.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFPTYIRYDVEFEKGEGVWLTDRSGRRWLDFASGIGVTGLGHN
                     HPRVRAALIRQAGQLWHLSNLFPHRLQERVAEALCRVSGMGAVFFCNSGAEANEAAIKL
                     ARRWAREAKVIAEPQILTFEGSFHGRTLATLTATGQEKVKRGFDPLPGGFRILPPENMD
                     AVREATGAATAAVLLELVRGEGGVKPVDPGFVRELADWCREKRLLLMVDEVQTGIGRTG
                     AWFAFQRYGITPDVITTAKGLGNGFPVGAMLAREELKPHLGPGSHGTTFGGNLLAMAAA
                     GAVLEELEVSGLIGEVEAKSRLLRDGLRQVLSPYAEVIDVRGLGLMIGVELTVPVQPFI
                     RELLHAGLVTLPAGETVLRLLPPLVVGETEIRQAVRIIGQVAEKRFGGKMEGLSEIREV
                     VAK"
     aSDomain        complement(26894..27847)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EG886_RS12370_Aminotran_3.1"
                     /evalue="9.30E-98"
                     /label="EG886_RS12370_Aminotran_3.1"
                     /locus_tag="EG886_RS12370"
                     /protein_end="332"
                     /protein_start="14"
                     /score="319.3"
                     /tool="antismash"
                     /translation="EKGEGVWLTDRSGRRWLDFASGIGVTGLGHNHPRVRAALIRQAGQ
                     LWHLSNLFPHRLQERVAEALCRVSGMGAVFFCNSGAEANEAAIKLARRWAREAKVIAEP
                     QILTFEGSFHGRTLATLTATGQEKVKRGFDPLPGGFRILPPENMDAVREATGAATAAVL
                     LELVRGEGGVKPVDPGFVRELADWCREKRLLLMVDEVQTGIGRTGAWFAFQRYGITPDV
                     ITTAKGLGNGFPVGAMLAREELKPHLGPGSHGTTFGGNLLAMAAAGAVLEELEVSGLIG
                     EVEAKSRLLRDGLRQVLSPYAEVIDVRGLGLMIGVEL"
     gene            complement(27858..28670)
                     /gene="argB"
                     /locus_tag="EG886_RS12375"
     CDS             complement(27858..28670)
                     /EC_number="2.7.2.8"
                     /GO_function="GO:0003991 - acetylglutamate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1174: acetylglutamate kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012899.4"
                     /locus_tag="EG886_RS12375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetylglutamate kinase"
                     /protein_id="WP_164491836.1"
                     /transl_table=11
                     /translation="MEKAVVVKLGGHAMDRMESRFLEQIARLHAEGTPLVVVHGGGPRL
                     SEFLRERGIVPRFVDGRRVTDEQTLEAARMVLAGDINKRLVSTLLMAGIPAIGLSGVDL
                     SLLRVKPADARLGFVGEVEEVNREALRSMLADGWVPVIASVGADQQGRHYNINADEAAA
                     ALAESISAKRLVLVTDVDGIYRTEGAKRIRLSKATLQQLEEGIRNGWITGGMIPKTRAG
                     IRCLRGSVEEVWITGGKSPVLPGEEGTGTCLVREEVKTGEAVSHLHPV"
     gene            complement(28687..29919)
                     /gene="argJ"
                     /locus_tag="EG886_RS12380"
     CDS             complement(28687..29919)
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /GO_function="GO:0004042 - acetyl-CoA:L-glutamate
                     N-acetyltransferase activity [Evidence IEA]"
                     /GO_function="GO:0004358 - glutamate N-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1220: bifunctional ornithine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014649019.1"
                     /locus_tag="EG886_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional ornithine
                     acetyltransferase/N-acetylglutamate synthase"
                     /protein_id="WP_277423819.1"
                     /transl_table=11
                     /translation="MEQGILIGKTPFVIVNEPNVASPKGFAAGGMHCGIKRKRPDLGMI
                     VCERPASAAAVYTTNAFQAAPIKVTQESLGAGGTLRAVVVNSGNANSCTGPRGLEDARM
                     MRDTAAELLGVNRHEVAVASTGVIGEFLPMDRIVGGLRQLTVSKEGGRSFAKAILTTDT
                     CIKQAEVRLTVDGVPVVVAGAAKGSGMIHPNMATMLAFITTDARISPDMLQSLLWKATD
                     ETFNMITVDGDSSTNDMTVAMASGLAGNRTLTPDHPDWEAFSAAFLHVCRELSKAIARD
                     GEGATRLIEVQVEGASDAKRAAAVARAVAGSSLVKTAVFGRDANWGRIVCAAGYGDPTL
                     DPEKTEVFLGDVQVVRGGIPLVFDAGAAEAELGRETVCIRLKLHSGEGKAVAWGCDLTH
                     DYVTINASYRT"
     gene            complement(29963..30994)
                     /gene="argC"
                     /locus_tag="EG886_RS12385"
     CDS             complement(29963..30994)
                     /EC_number="1.2.1.38"
                     /GO_function="GO:0003942 -
                     N-acetyl-gamma-glutamyl-phosphate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006592 - ornithine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011886929.1"
                     /locus_tag="EG886_RS12385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="WP_124728427.1"
                     /transl_table=11
                     /translation="MKAAVIGSTGYGGAELIRLIEGHPELELSAAVSTSQAGEELGTSW
                     LSLSHLGRMYEELDPERVCRKADLVFFATPPGICARWAAPFLEAGCIVIDLSADFRFHD
                     PAVYEERYGKPPAPKEWLERAVYGLSEWNRERLREAELIANPGCYPTATLLALLPLLRE
                     GIVNPAGVIVDAKSGVTGAGRGLKRELLYCEVNENLRPYRVTGHPHTTEIEEGAARFAG
                     RELRISFVPHLVPMNRGILVTVYASLMNKYTEKELTDLYRDAYRDKPFIRILTDRPPET
                     GAVRGSNFCDIAVRVDERTGRVILMAAIDNLMKGAAGQAMQNANIRLGWSEETGLKALP
                     QYP"
     misc_feature    30963..30980
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    31045..31060
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     misc_feature    31093..31104
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    31125..31140
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.05"
                     /tool="antismash"
     misc_feature    31127..31141
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.02"
                     /tool="antismash"
ORIGIN
        1 tcaaacatgg agacgtatgc caacagatga tgggcaaacc ggaccggttg agcccgctgg
       61 aggtgggtgt accccggcaa cacggtgtcc acgtgggctt ccgcctgctc caagagcgcg
      121 tcctgcaagt cgaggagaag ccggacgatc tcgaccgtca ctttgcggac gtacaggtgc
      181 atgtccaccg ccacctggtc gttccggctg cgggccgtgt gcaattttcc gccgagcggc
      241 ccgatttctt cggtgagcag tttttcgatg ttcatgtgaa tgtcttcatg ctcgatccgg
      301 aacttcgcca cgccggagcg gattttttcg cgcacggtgt gcaaaccgga gatgatggtc
      361 tccgcttctt ccggggtgag gatcccgcac tttccgagca tgtcggcgtg cgcgatgctg
      421 ccttggatgt cttcctcgaa caattccttg tcgaacggga tggaggcgtt aaattcctcc
      481 acccagcgat ccgtcggttt ggaaaagcgc ccgccccaga gtttcatcct tctcgtcctc
      541 catgtgcaca tttgcataaa tattcgtcgg caatccccac agcttgatga acccgaccgc
      601 cgcctggtga tcaaactcgt catccgcggt gtacgtggcc agtttttcat cgtacagcga
      661 atacggcgag gttcttccgg tcacggtgac actcccctta aacagcttca cccgcacgtc
      721 gccggtgacc ggtttctggg tctggtcaat gaacgcgtcc agcgcctttt tcagcggcga
      781 gaaccagaga ccgtcgtaca ccagttccgc ccatttctgc tcgatgaccg gcttgaagcg
      841 ggcgatgtcg cggggctggg tcaggaactc cagttcacgg tgagcggtga tgagagtgat
      901 cgccccggga cattcgtaca cttccctcga cttgatgccg accaggcggt tttccacatg
      961 gtcgatccgc cccacgccgt gctttccggc cagcttgttc agtgcggcca aaagttcatc
     1021 aaacggcatc gcttctccgt tcagcctgac cggcacccct tgttcgaagg aaatgatgat
     1081 ctcatcgggg gtgtccggag cgttttcgac ggaggaggtc cattcgtacg ccgcttccgg
     1141 aggagccgtc cagggatttt ccagctctcc gcattcgcag ctgcgtcccc acaggttctg
     1201 gtcgatgctg aacggattgt ccaaatcgac cgggatggga atgccgtgtt tctccgcata
     1261 ggcgatctcc tcatcccggg acatcgccca ttcgcgaacc ggggccacca ctttgagatg
     1321 cggggccagc gcggtgacgg aaacgtcaaa gcgcacctgg tcgttcccct tcccggtgca
     1381 accgtgcgcc acggccacgg ctccctccgc cttggccact tccacgagca cctgggaaat
     1441 gagcggccgg gacagcgccg ataccagcgg atatttgcct tcatacatcg cgtttgcctt
     1501 cagcgcggga atgagaaaat gatcggcaaa ccaccgtttg gcgtcgacca cgaccgattt
     1561 gaccgctccc accttgagcg ccttgttttt cacgaaatcc aggtccttcc cttcccccac
     1621 gtccaatgcg acggcgatca cgtcataccc gtaagtctca ttcagccatt tgatggcgac
     1681 cgaggtgtcg agaccgccgg aataggcgag aatcactttc tctttttgca tgcgtatccg
     1741 ctccgttcca cataaaaatt catgctcatg catgattata cgaagttcat gcaaaaaaat
     1801 ccacccctga ttcggggtgg attccgtttc cattttccgg atctcaagcc ttggcttccg
     1861 gtcccgccac gtttctctcc gctccgccga aaaattcctg tcgcttcgtc agataggaat
     1921 cggagctgac ctgaaggttg ccccggaaga agatgaagga caagagcggc ttctcgatca
     1981 gcacgtgggt caaccatccg acgagaatca ccgcgacgat gatcaacgcg aagagcaaaa
     2041 gcgggtcggc ccatccgagc cagtcatcct ttccggaaag atggaacaag agcgtaagca
     2101 tcggttcatg taccaggaac agggaatacg aagcctgacc catgaattgt atccaggcgg
     2161 gcaggcggat ttccgttttc acgtcggccg cggccagacc gaacaacagc agactgaccg
     2221 gcaccccgta gttgtacatg tcatccagcg gaacccagcc ataaagatca ttcaacacac
     2281 cgagcaccgt cccggtcgcc ccgatcagaa agatccatgc cggctgcttc actggaattt
     2341 tgtcggtcag gtgggcgatg aaggctccgg cgaagaagta gaggtggtac ttgctgaaga
     2401 gcacctgaag cacgggatgt tccaggttca cgtcctgggt gaagaaaatc accaccgcca
     2461 gaaaccacag cgccgccacc agcgtccccg cgttccgtcc caagaagaga aagaggaaaa
     2521 agaacagata gaacacgagc aggatgctga gcaagccgga cgaggaaaga agggaatcct
     2581 catggggaat cagcagcacc gacggtccga tgctgtccag agaagccttc tgtccggtca
     2641 gaaaggcgga aagcggaatg atggcgatca ggatgtacca gtagaccgag tagatgcgaa
     2701 tcagccgctt gatcaaaaat cccctcgcgg tccgtttgtc tccgatcgac gatttgtagg
     2761 aagcaaacag gacaaaaccg ctgagaagaa agaaaaagtc catcgcaccg aaccggaccc
     2821 ggtcatccag tcccggaatg agttcgacat cccagtggtg aagtcccgcc cggtgagccg
     2881 ccagaacgac gaccagcagc gagaagattc ccctggccgc gtgcagcaag tgatactttc
     2941 ggagcatctt tgttccgacc tttctgcgac tgagtcatca cgggcattcg gcagcggtcc
     3001 ggaagtcatc cataactgga cggaactgcc acttccattt tggcataaaa aaagtttgtt
     3061 ggttgagact tcgatgacat ttcatgaagc gttcaaactt cctgcctgtg aaatgttccc
     3121 gtttttgacg gaagtcactt tacggaacgg gagcaccgag gcggtataat gaaaagatgc
     3181 ggtacccgcg tcgccacccg ccgccttcgg atctctccgg ggcagccgaa atgcaagtca
     3241 ttcaacgatc ggctcgcggt tttcgacacc cccgccggac gggaatgatt tcgtcgggaa
     3301 ccgatccgtt tgacccggag gacatcttgt tgcggggatc gtgagacggc gccccgacat
     3361 gccgactttt ccgagagctt cttcgcgccg aaccgcacat tgccatgacg gaaggaagga
     3421 aacctgatgc aaccggttcg tttcatcgcc ttgcccgtcg ccggcctgtt gttcgttctg
     3481 tccgcctgca ctccggccac ttccggccag gaacatcctt ctccctccgc atcttcccgg
     3541 accgccgaac ggcccgctcc ggatgtcgac aaaagcggag aatccgttcg ggaacatccg
     3601 gaggaacgga ttcgtgaaac ataccgggga gtcacgccca aagagtgggg agaacaggtc
     3661 cgcggagtca tcacgcgttt tgaaacgaag gaaccgctga tcgccctcac cttcgacgcc
     3721 tgcgggggac cccgcggaag caaatttgat caagcgctgg tggatcatct gatccgtgaa
     3781 caaattcccg ccacgctgtt tgtcaacagc cggtggatcg atgccaaccg ggacacgttc
     3841 ctccgccttt cggagaaccc gttgtttgaa atcggcaacc acgggacgga acatcgtccg
     3901 ttgtcggtca acggtcgctc cgtctacggc atccgcggaa cgtcggatcc ggctcacgcg
     3961 tttcgggaag tgtggctgaa ccatgaaaaa atccggaatt tgaccggacg ggaaccgaaa
     4021 ttcttccggg cgggaacggc ctattatgac gaagtggccg tccggatcgt ccacgaaacg
     4081 ggagaacggg tggccggctt tgacgtcgtc ggagacggtg gagcccgctt ctccgcgtcg
     4141 caggtgaagc aagccctgct gtccgcgaaa cccggctcca tcgtcatcct gcatttcaac
     4201 cagccgaacg gagagacctt tgaaggactt cgtcaggcga tcccggtgct caaacagcgg
     4261 gggttccgct tcgtgaaact ggaggatgtg ttgtgagcgg gagccaacgc tcccgctcaa
     4321 accagccgga tcccgaacca tcgctgcaag gcggctctcc gctccggcag cgaccggacg
     4381 ggaatttttt tcttttcgcc cctctccgtg atcgtcaagc cttcatccgt cagcgtgatc
     4441 cttcccgttt ccgtggcgat cgtgcacacc atccgccggg tgaagccgga ttcgggggaa
     4501 gtctgatggt ggatgcacat gggcatgaaa tcggacaaaa tccacggcct gagcgtaaat
     4561 tggtgctggg gcttccactc ttcccccggc tgtctttttt ccagcaccca cgcatccgga
     4621 tcggccgccg gcatcacccg gtaatccccg ctcacatccg acaccacgga gccgtcgagc
     4681 ggcaccggtc ggcgtgccga atctccgaat cccacatcca ccagaagtgg ttgctcatca
     4741 aagacgagca gggtcagatg atcaaattcc ggtcccgggg ttccgtcagg ccgaaacacc
     4801 cgcgcagaca gcaagcgaac ccggtacccg agcttctcca acaaccaggc gaacaggccg
     4861 ttgagctcat aacagccgcc gccccgtttt cgccggacga ctttttcgta aatcatcggc
     4921 aaatccaaca ggatggggac gttcgcacgg atatccagat tttcgaacgg cacggtgagc
     4981 aggtgttgat gcatcagcaa ctccaacctg ttccgaccgg gcttctcggt ttctttccgg
     5041 tcgatcccca atcgtgtcag catctccgtt acatccatgc ttttcacccc atcgccatgt
     5101 catgatcatt tcccgggaaa tccatctctc aaagcaaaaa gcccgccgag acgacgctcc
     5161 gccggagtga acgcatcttc ggcagaaaca agcaccggcg gatccgtgac cgatccatgg
     5221 atcctacccg ctcgcgagtc gaatctcaac tccgaatccc gaccggcaaa aacaaagagt
     5281 cattgccggt gatttcctga tcgacccggg agacgatggc cgacgcacgg ccgccgatca
     5341 gaaacgagcc ccacaattgc ttgccgcgaa cggttccctg aagcgtttcc acctcgaccc
     5401 actccaattc cgccaactcc tggtacacca tcggctggtc ccaatacaat gttccaccgt
     5461 cttgagcgat gactcctccg gtggaatcat acagcctgac gccgcctcct tcccgcccga
     5521 acaccggctt ggagacgtaa gggcgttttc cgtgaaacac attgtccaga taggtgggaa
     5581 gcatgtgatc ccggatggtc tgtctctcct cgtccgtgaa gaacagatcg ctctccgcca
     5641 ggttccagat cagggcctgc aacgccttgg tttgggaaat caaggcggaa ggcggattga
     5701 tcatggccag ccggcgggaa acggtgagct ccaggatgcg aatccccgtc ggaaatccgt
     5761 ccttgtcacg gtcctttacc atcagttcga tcggatgcag gcggtaccag acatccaccg
     5821 gccgccagtc atccccgtcc ctggcatgga gccttccctg acagtacgaa agttcttcca
     5881 gcggcacgaa ccggccgtcc agtccggagg catccagcaa atagcgggtg gttccccggt
     5941 cttcctcatg ccggcctaga gagctgaaca cgatggaatc ggaagcaaac cccagacggc
     6001 gatattcccg gaccatggtg gcaaatgcat cacggatgtg ctcccgcatt ccgtgattgg
     6061 gattttccac cccgaacttc ccgcaaacca cgccattcac atgaaatcct tccaccagac
     6121 aggtcggggt gtcgctgttg aactccagca tcttcagccc tcgcggcgtc cgggcaaaat
     6181 caaaccgccc gaccaaggtg ggcatttccg cacacacgga catcctgacg gcaggccggg
     6241 ccgcttcggg aattcccaac tccgccagca gttcatcccc cgctttttgg acgacctcca
     6301 tggttcgggc gaaaatccgg cccaaacgtt cggtcacgtc ggcgatttcc gcgcgaaatt
     6361 cgggagaaat gaggcacaga tcggcgagcg catattcttt tccgtacatc cagtcccagg
     6421 tgaagacgcc ttcctgacgg agcgactcgt aaatctcgtg ccgcaggcgt tgatattctc
     6481 ccgttttttt catcccatca accgccaaac ccctcgtcat catcgtaatc ttcatacagc
     6541 ttgagatatt tgcgcttgcc gtcttcttca atccaatcat tcggatcgac gggagtgccg
     6601 tcttcatcac acttccgatc tttgttgtca tcggcgcaat aatccagatc acacccggac
     6661 acggtcaaag agatcaaagc ggccgcgaac aacccaacca ccttcgaagt ctttccccca
     6721 aacggaagcc gcttttccac ccgtccccct cctctgaata ttctgacatg catttttggg
     6781 cgtggaggga aaatccgggc atcggtcctg acgatgcccg cgtgaaacca tccggcggac
     6841 ggctgtccaa ggcgccttcc gcgacggatg aaaaacgcga aacccacgaa tgaagccgtc
     6901 tcggaaatga gttgacggcc ttccgcccac agttttatac ccgttttctt ttgtttcgac
     6961 acggatttat cccgcgttgg ctgtttcttt gccgcggttt tttgcccact ttcccaccag
     7021 cagcacaccg gcgaccacca gggcggcaaa cacgtatttc agccaatcgg cctgggcgaa
     7081 cacgtcatgg aagagttttt cgtcagcgat catttttccc gccgtccaag cgagcacacc
     7141 ggccccgaca tagatgaggc gcgggtaacg ctccagaagc cgcagtacca ccgtgcttcc
     7201 ccacaccacg atcgggacgc tgatgagcag accgaggatc acgagaaggt agcttccgtg
     7261 cgcggcaccg gccacggcca acacattgtc cagccccatc accgcatcgg cgatgatgat
     7321 cgttcgaatg gccgcccaca tgctgtccgc cgcctggaca tcatgtttct tttcctccaa
     7381 caggagcttc catgcgatcc agaccagaat caatcccccg atcagaagca gtcccgggat
     7441 cttgagcagc caaaccactg caagcgtggc ggccgcacgg atgatgatgg ctccgacggt
     7501 tccgtacacg atcactttct tttgcttgtc tttcggcaga ttgcgcgccg ccagtccgat
     7561 gacgatggca ttgtcaccgg cgagcacaag gtcaatgatg atgatggaaa gaagtgcgct
     7621 caaaaactca aacgacagga aatccatctt gaactcctcc ttgttgcact cccaaaaaat
     7681 agaaatagac ctttactttg tccccaaagt aaaggtctcg ctgacaacga aaacgttgcc
     7741 cgacagagcc ggggcgatcc gcccgtactg acgactatgc cgaaaagcta ctcccctgtt
     7801 accgatccac atgctatttt tttcaactct catcttatcc cacgggattt gtccgagtca
     7861 atcaaaatat ttgcaagatc caaatcctct attcacaagc aggtttgaaa atcattttgt
     7921 atcagaatta aaacctcggg catgcaaaag ggattccgca tatcaaatcg aaatgtaatg
     7981 atgggcttcg ctccggccgt ccgccgaccg cagcccatac agaataagga ggaagatccc
     8041 tttgcgcctg gtttgcctca tcgttgtaca tccttcgccc cataccgcat cggagaccgt
     8101 atccaggtgg aaggaagaga tccgaaaacg gttgccggaa accgcccctg ttcgccgcca
     8161 tgacgcggag gaaaaccgtt tgctctggct tcatgcttgc tgtcaggaag aagtgagaac
     8221 ccgtttggac ggcttggacc cctccgccgc atccatcctc tgcaccgacg gttcgcaaga
     8281 cgtgtggctg tcctttttgg ccgtcggagt ccggggattc gtttcgttcc gcgaccaaaa
     8341 agaacttccc ggagccatcc gcgccgtgaa cgccggcggc ctctatttca gccggtccta
     8401 tcatgaacgg gcgggagaca tcttgtactg gaatcatctg atccaccggg agaaccattc
     8461 tcttccgctg acccccacgg aaagacgcat catccaggaa atcgccatgg accggtccaa
     8521 ccgggaaatc gcccaatcct tgcgaatcag tgaacggacc gtggagcatc acgtgtcgac
     8581 cgcgcttcga aaaaccggtg cgaaatcgcg cgtcggattg gtgatccgca ccctgaaaaa
     8641 tttccaaata aatgttatat aaaattctta atttgtggaa aatacggatt cgaaaatcgt
     8701 ctttctgtga tataaaaaga ctagattttg atggattgat ggattttcat cccaatgcat
     8761 gcatgatccg gatggatctt ccgcgcgaac gtatgggtct tccgcgtctc ttcgggttcc
     8821 ctcccggtcc gtcaaagcgg ttccgaaatc gttttcattt tcggacggca gcggatcccg
     8881 acataatcgg aaccgttttc catggcgacg gatccggctt tccgccatcg cttcggggcc
     8941 tcctttttcc ggaaaggagg tgaatccttc ccgagcgccc cgatcttcct tcccccatct
     9001 tcattcccgg aatcgggtgc ggctcttcat cctaccggag gcaggtgaaa agtggtggaa
     9061 gtgaaagatc tggagatcac cggactggac atcatggatc tcagcgatgc cgccgcactt
     9121 ccggaaacgg gagcttcttc gggagaatcc agctgctccg tggcgagctc cacctgcggt
     9181 tccagctcct gctgcagctc ctgttggtaa tgattgcctg aacacgtaca aaccggaagg
     9241 gagagtcatc atcgatggac atggagatcc ggcatcttga agtgacggga ctggaagtga
     9301 tggagctgag cgacgccgcc gcacttccgg aaacgggggc ttcttcgggc atcacgccct
     9361 gcacgtattg ctccacctgc ggctccagct cctgctgcgc gtcgtgtcaa tgaaccgttc
     9421 atccccgcag ggacggacaa gaaccttccg tttcactccc cggtctgctt gtttctccga
     9481 gtgattggcc gaatcctgaa aaggaggtga aactcatgga aatccgtgac ctggaaatca
     9541 ccggtctgga agtgctcgac ctgagcgacg ccgctgccct gccggaaacg ggagcttctt
     9601 ccggttccac ttcctgcagc gcttcctcca cctgcggttc cagctcctgc tgcgcttcct
     9661 gctgaggagc gtaccgggct tgatcttgtc aaggaggtga tcccatggag atccgtgacc
     9721 tggaaatcac cggtctggaa gtgctcgacc tgagcgatgc cgccgctttg ccggagaccg
     9781 gagcctcttc cggttcttcg tcctgcagcg cttcttccac ctgcggctcc agctcctgct
     9841 gcggctcttg ctgatgcatg ttctgattcg cgtttttcgg aaagcgaagc aaacgggtgt
     9901 ggccgcaccc gggtgcttcg cttccatcta ttttaccacg tcatggcaga tgattccatc
     9961 agacgacggg cttattgccc cgaaaaggag gggtttgtgc ttggctgttt ccggtgagaa
    10021 cctcatccgt cccccgaaac gcgtttcccg ccgtctgttt ccccatttcc tgatccgcac
    10081 cggcggactc cccgccgatg gtctccgctt catgcgtgcg aaggaaaccg tggagcgctt
    10141 gcgggaaatg acggctctct cccggcggtt gtccgaagag aacggggagc tgatcgaagc
    10201 ggtggaacgg gaagtcccgc aggttcgctc cgattcgctc cgcaacgcgc tcatccggtt
    10261 caaacgggac ctgtacaacg gtagaaagcc caaggtccgc gtgaccgaag aatgggcgga
    10321 actgactccg gagcttgcgc aacggattcg gctgcgactg caaaacgagg agcgactggt
    10381 caaactccgg gaagaagccc gaacccgctt tgaagaggag ctgcttgatg ccagacgcca
    10441 tctccggcaa acggtgaccg accctcgcct gttggccggc atcgcgctca ccagccagga
    10501 gctccacgaa aaggcggtca agtacataga gacaccggtg gagcggcaaa aatcccgcct
    10561 gcgcaaggtg gagaccagcc tggtgaaatt cgtgacgcgg gcgtcggtga aaaccagccc
    10621 gttcagcacg tttacggccg tgggcacggg ctcttgggac gaacgggcgg aacatgctcc
    10681 gtttaccctg ccttccccga accaccgggt gttcaccgag ctgaaccacg ccaatctcct
    10741 gcgggtgatg gagggattgt gcgcccatcc ggaagtgcgc gtccagcttc ggtatcggat
    10801 caatccgacg ctcatcatcg atcaggggcg ggtcaaatac attcgccgga cggatgattc
    10861 caagctgcgt ccccgggtgt tcaaaacgct ggagaccccc gtatccctgg acgccaatcc
    10921 ggccattcgc ctggtgctgt cccgtttcgg ggatgcttcg gaattgtcgt atgccgaatt
    10981 gatccgccgg ttgacggaag cgggccaatt cccggccgag caactgcgcg ccttcgtgaa
    11041 tcagctcata tccctgcaag tgctggttcc ggtactcccg cgtcacgagc agaaccccga
    11101 tttggccggc tggttgatcc gctggctgga atcgctggac ggggacatcc cgaaaacggc
    11161 ccgggaccat ctcatccgga tccgggaatt ggccgaggcc gcgcccgacg acaccccgga
    11221 aacccgctcg cggcgtcttc gcgacattcg caacgaattt cacgcgctgc gcaagtcggt
    11281 cggctttgag ttgtccgacg aatccctggc cctcctcctg ttcgaggacg cgatcctgga
    11341 agaagaagcg cggatgaatc cctccgcctg ggaacggcat ctggatgacc tcttcgcttg
    11401 gcagcgattg cttcccgtcc tggacgtcaa gttccgcatc cagtcgaaaa tcgccgccca
    11461 attcgtcgag atgtacggag agaacggcat ctgcgaccga ccgggacggt tcctcagcca
    11521 ggtgatcacc tccatcaccg actacttccg ttcgatgctc ccgtccaaca tgatgaaaga
    11581 cacggagctg cacaacgacg tggaaaacgt tcgccggctg aatgaactga aacgggaact
    11641 cgggaaactc atcgccgaaa aactgcgctc ttccgaagag gaagcgtttc tcagccggga
    11701 ggagattgag cgtctgaccg aacggatccc cgcccaggtg cagcaccgtt tcctcaccaa
    11761 cgacgcgttt gtccagccgg cactggcaga cggcaaaccg ctgtgggtcc tgaatcactt
    11821 gtatgtgggc aacggcacgt ttttcacccg ttttttgccc tggttccggg aagagttgac
    11881 acagcggctt cgggaagagc tgcgggagct ggttcacccg cggacgctgg ccgaattgtc
    11941 cggcgtgttc gggttcaacg ccaatctgcg gccgagactg gctccgtttg aactggattt
    12001 gcccatgttg ccgccggcgc gggacggcct cgggccggac gaggtgattt cgtgggagga
    12061 tgtgatcctc aagtacgaca agcgggagga ccgggtgaag gtggttcatc cgaaacacgg
    12121 cgacctggcc gttttgttcg ccggtaccct catccccgcc ctgcttccgt tcgtggtcaa
    12181 tttcctggtg acgcagttca cctgcggcaa catgccggaa aacctgttcc tgttcgccga
    12241 ggaggagctg agtcccgatg agcgtcaaaa gatccggatc tggccgcgac ttcgggtggg
    12301 agatgtggtg ctatcccgca aaaaatgggt gattccccgc gggcacctcc ccaaacggga
    12361 gccgaatgac agcgatttcg actggttcga gcgcgtgcat cgctggaaag aggaaatcgg
    12421 atttcccgat cggatcttcg tccgcttcat tccgctggac gattccgaaa acccgttcgg
    12481 tgaggacagg gagccgtccg atgcctcccg gaacttcgac ttcaccgact ggaagccgca
    12541 atggatcgac tttcaaaatc cgctgaccgt gaaactgctg ggcaaaatga tcgccgagca
    12601 gcccaccggc atgatcgccg aagagatgct ccctgatctg gaacatctcg caaccgaccc
    12661 ggatgatcac aaacgggtga atgaatgggt gatcgaactc agccaagttc cggaggtgga
    12721 atgatcccgt gtggaaagcc gttcgcatca cgtattacga agacaacaag gatcggcttc
    12781 tgacggaagc gatcaagccc gccgtggaaa agcttcaaac ccgcggactc ggccgctggt
    12841 ttctgaggcg ccattggaaa cggggccccc acatctccct ggtcctggaa gacacgaatg
    12901 agcgattgga gaccgactgg ttgccactca tccgggaaac cgtacttccc tggctgaacg
    12961 accatccgtc acgcaaagag atcgatccgg atcaatacct caagctgagc gagaccttgg
    13021 gagcctggga actggagccg gggccttatc ttcccctgtc tcccgacaac agcctgaacg
    13081 tcgagcccca cgatcgcagg gaagatgtcg tcagcggggc acgcgtggcc gagctgttgg
    13141 aagcgttccg ttccgatgtg gcgccggtga cgctggagct gatcgcggaa agcgccggaa
    13201 accgcggaaa acgactggaa caaatgatcg gactgatggc ggtcatcgcc gaactgtacc
    13261 cgctcggagg aatcacgcgc gggcatttgt cataccgttc gcacgtggaa ggttacctgc
    13321 acacgtttga caccgacggc cgtctgcgcg aaaccttccg gcaacgggac cgggaactgg
    13381 gcgggcgcat cgatgagctg gtccgggcgg tgctggcgca tacgggagaa gaaggcggtg
    13441 tgtatcacgg accggaccgg tggctccgcg cttgggcgga agcgtccctt cgcctgtaca
    13501 cggaagccaa gaccttggcc gacgccggag aactgacctc gcgaaccgat cactatcggg
    13561 agatcgccgc caccatcggc gaagaggcgg tgaaacgatg ggatccctcc gggaatgagc
    13621 ggggactcag cccgtttcat caaaacctgc agtcccggga agaaggcatg cgggtcctgc
    13681 aaagcccgga atttgccgca taccggattg tggtcaatgc cttctacgcc catctgcccc
    13741 tgtttgacat caatcctcac accaagcatt tgttgtgcga actggtatcc aatgcaaccg
    13801 agcggatcaa gggtgtgacc tggcagcaac tgacagggtt tggccaagga ggaaccgcgg
    13861 atgcttgaac aacgaccgaa atggagacgg cacgtccact tcgctcccac ggagaacggc
    13921 gtttatttcc acacctggaa ctccgaattc gcgctgaaag gaaaagggct gcacgcctgg
    13981 gtggaacggc ttgccctcca tttcaccgga gagaagacgc tgaaggagct gaccgacgga
    14041 ttgggggatg cacaccggcg tttcgtcctg caattgacgg aagagctgtt caagcgtggc
    14101 gtgctcacgg acggaaaccg ggaagaagcg acaaccctgt caccgtcgga gaaagagctg
    14161 tacgacgaca cgctggcctt tctggagctt cacgccgagg atgcaaaaaa gcggtttctc
    14221 cgctttcgtc tgcaccgtcc gcgggtggcc ggttccggca aagcgatgtt cgccctcgtc
    14281 cggtccctgg tgaaaatggg cgtgaaatcc cccgttctgc cggccgacgc ctccggggac
    14341 atccggcgcc tggccgagga atgggccgcc cgggatcccg cgttttcccc cgtctggcag
    14401 gatccgctct cccccggaga cgaacgggaa gcggaacctg tcgacgggat cattttcatc
    14461 ggggaatgga cggagcggga acactttgcc cgctggtccc gttttgcccg tgaaagaggc
    14521 attccgttcc tgcccgtcac gattcatccg tccggcggat gggtgggccc gctggagtct
    14581 ccggaaagca tcgccacctg gcaatgcgcc cgggaccgtt tcacggacgc ggatgcttcc
    14641 ggagaaaaaa cggtgacctc ggacctgctc ctcggcaaca tcggcgctct cgaatggctg
    14701 aaacacgtga ccggggcggc tgaaagcgat gtcatcaacc acgtgatgga cctttcttcg
    14761 aagcggctgg aaacggtgcg acgccgcatc catccgtctc cgcttgtcct tgggtcctcc
    14821 cgcctcgttc cccctgtttc cccgccggac tcaggcgaag aaccggaaga ccagggggtg
    14881 tttctggaca aggccgaatc gctgaccgat ccccgcttcg gcgttctgct ccgcatcagc
    14941 ccgggagacc tgatgcagat tccgctgccg ctcattgccg tcaccacccg cattccgggc
    15001 gccggcaaag acggcatccg cacgttcgtc ggagccgggg aaacggtgcg tgacgccacc
    15061 gaaacggcct tgcgggaagc gctcaccgct tatgcccgcg aactggaagc cgtcgtgacc
    15121 ggaaatgccg acacgaccga agacggaccg gtttccgcgg tgtggagcca cggccggtcc
    15181 cgggacgaat gggcgggaag cggattgctg cgttcctgga tccgggtgtc cctgtcacgc
    15241 ggcaaccggg gattggttcg gctgaaccgg gaagacctcc ccgacggaaa acaccgccga
    15301 tatctgaaaa tgctcgacat tcgttacggc cggaagccgg aactgtggat gtttcgttca
    15361 caaacaccgc gggccgtcgg catctttttg accgaagacg gaaatctgct ggccgaggga
    15421 gcgggccgga ccttccatga agccctggaa cgggccttgc cggaagcgct tcgccgcctg
    15481 caactcgccg agcatcaccc ggagttcgcc cctccagcgg aagcggtatg gttcccccgg
    15541 gaagaagatc cggaggcgga cagaaccatc cggatggacg agccggttcc cgactgggcc
    15601 gaatggctga aggaggcgga gcgattcgcc acacaaagcg gattccgcat tcgacgggaa
    15661 ccctggaccc gcgacccgtt cccggcggaa ctgggcgtgt gggtcggaca ggtcggctgg
    15721 gaaggaggaa atgagccatg agccacacgg tctggttgtg ggcagaagga cggttggcgg
    15781 acatgctggc accggttctg gaagaggtgt gcgaagtcgt gcgggtggac ggattgccgg
    15841 atgaaccggg acccgggcgg ccggatgccc tgcttctgtg tcatgacgcc cgcctgttgg
    15901 accgcgaagc ggacgcacag gaccgggcca ggcgatgggg cgttccgttt ttccgcattc
    15961 atctgtatgt tgatcgcgtt tttgccggtc cctgggtcct gccggacgaa cccggatgcg
    16021 tgcactgcgt ggagtggcga atgagcctgg ttcatcccca gcgggagatc tggcacagtc
    16081 ttgcgaaggc acagcgcatg catgcggaag ccggcattca ccgcggatgg agtcccccgt
    16141 tcctggactc gctctccctg atcgtccggg acgagttgga gcgcctgctg agcggaaaac
    16201 cgccacggct gaaacggagc atctacgtgg ccaccgacgg aatgatgaac ggacggatcc
    16261 acgcgttcca gcccaacccg ctctgcccgc ggtgcggaaa cctgccggat gacacgccgg
    16321 agagagcggt gttccgggtg cggtccttgc cgaaaccgca tccccgcacg tggagactgc
    16381 ccaacccgaa catccgaaac gacgtgctgc gggaagcctt ttacgattgg cggacgggtc
    16441 tgtttcccca cctgtaccgg gatgtgtatt cgcgcttcat gccgattttc ggtgcggaaa
    16501 tgccgcttcc cgatcgcaaa tccacggaaa tcggtttcgg acggaccgac acgttccggg
    16561 actcggaact gacggcgatg ctggagggat tggaacgata cgccggcatg gtgccccgcg
    16621 gaaaacggac ggtccaccgg gcatcgtgga acgaagtgcg cgaccgggcg attcatccgc
    16681 cggagtgggg catccaccat cccgaccaac gggacgagcc cggctatgcc tatgtcccgt
    16741 acagcgatga tctgaaagtg aactgggtgt gggggttttc ctggaaagaa caaaaaccgg
    16801 tgctcgtccc cgagcaaatg gtgtattacc gcctgcccga tccgccggag cgaccgacca
    16861 accggtttgt ctatgagaca tcgaacggtt gcgccatggg cggttccctt gaagaagccg
    16921 tcttccatgc cctgatggaa gtgatcgaac gggatgcctt cctggtttcc tggtacaacc
    16981 ggctggccct ggacgagatc gatgtggaag gggttcacaa ccggaacatc ctgctggtga
    17041 aagaccgggt cgaagccaac ggataccgtc tgcatctgtt tgacatgacg atggaatccg
    17101 gcatccccgc cgtgtgggcc ctgatgatca atccggcgga agacgcgaag gtgaaaacct
    17161 attcggcggc cggcgcccac ccggatccgg aaaaagcgat catgggggcg ctggtggaag
    17221 tggtcacctc cgtgcccatt tacgaggaga tcatgccggc ccagcgggac aaggcggaac
    17281 ggatggtgca cgaccccggc ctggttcagg aaatgcacga ccacgtgctc ctgtactctc
    17341 atccggacac gcttccccgg ttcgatttcc tgttccggga gaagaaacgt ccgcgtccgg
    17401 tgcgggaact gtaccgccgg tggtacgaag aggagccccc gggcgacctg ggagcggagc
    17461 tgaaggagct gttggacaag ctgacccgtc tgcacggaga tgtggtgatc atcgacgaaa
    17521 ccaccccgga actggaggct ctggggatcc gcgccgtcaa aacgctggtt cagggcatgc
    17581 tcaccatgtc gttcggtcac caataccggc gcatcgtgat gaaacgcgtc ctggaagcac
    17641 cggttcggac cggccgccgt ccatccccga tccgggaaga agagatcaat ctcttcccgc
    17701 atccgttccc gtaagcaaag gaggatgccg gtggatacgt ttgaacggga attccgcgag
    17761 atgctgtacc gtcaaaccta cggccggttc cgggcccacc ggacccccga tgaccacact
    17821 ccgcccgatc cgctgatcac ggacaaaccg tgcctgaagc gaatcccttt gccgacggag
    17881 cttcccgacc tgggatcgct ggacagccgg gggccggcgc acggggattt cggctccgtt
    17941 tcgcttgcga accggttgtc cgcgctgctt cactgcacgc tgggcgtttc ccggctggaa
    18001 atcggcacgc cgaggccact gcaccgcccc gttccctccc cgcgctgcct ccacgcctgt
    18061 gaactgttgg cggccctgcc gccgggcagc ccgacgggcg agggaagttt ccgctatcat
    18121 cccgttcgtc acgaactgga agtgcgccgg gaagaacggg tctggcacga actggagcag
    18181 gctctcggca tgccgcttca cgatgcggac gcggtgcttg ccgtgtctgc cgaatggtgg
    18241 cggatcgcct ggatgtacgg ggacttttcg tttcatctgg ccacgctgga agccggccat
    18301 cttcgcggcc acctgctgtg gctggccgaa ccgctcggct ttcgggccca atggatggac
    18361 cgttttgaca gccgcgcgct gtccgcctgt ttcgggttga atcccgaagc ggaaaccctg
    18421 ctgtcggtgc tggtgctgag aagcgtgtgc gaacaacgcc cggaagcggc tgaacggctg
    18481 cccttccgga ccgggattcc cggtacggac accgacggag acgggcaggc gaacttgctg
    18541 aagcaatgcc ccgatctgat gagactgacc gaacggaccc ggccgcatcc gccgtcggtc
    18601 ggaaggcgct tggatcctcc gatcgcttct ttcccgcttg ctccggcgga ccgtcctttc
    18661 tgcgaaccgg atctttcctt cggcaaatgg agatacccgc gaagagaaga cattctgaaa
    18721 aggcgcagcg gcggaaatga tgtgctgggg ctggcggccg acggctcccc cgtttccctc
    18781 gaagagctgt ccgcggtact gggccgtctg cgggaccatg tcgccgtgca tccggaactg
    18841 gttcgcggca tccgcctgtt cctgtgggcc cgacgcgtgg agggactttc tcccggcatc
    18901 cgggaagtcc ggcccgacgg aagcctcgtc tctctccgaa cggacggctg cccctccctg
    18961 gcggggatcg gcacggcgga cccccgcacc gcccatttgg acagctttcc gatcgcattt
    19021 ctgttcaccg ccgattacat cggcgaatac cggttgacgg ggccggaagc catgcctctt
    19081 ctccagcaaa gaaccggcca tctgacgcag tggctgatgc tgcatgccac cgccatgggc
    19141 tggatggccc gtccggtcaa aagtttcgac gagcttcggg ccgaagagat tctcaacctg
    19201 acggagacgg gggaaaccgc cgtgtatctc ctgctcgtcg gaaaacaccg gcacccgttt
    19261 ctttcgcttg acatgagcct gggaggtgtg tgactcatga gttctgctgc ccatccggac
    19321 tggctggccc tgcacgcgtt cacgcacgac cccttcgggc aggattccct gctgctggag
    19381 ggaatcttgc ccgccctgag gcgcctggaa aggaaagggg ctttccaaaa atggtttttt
    19441 ctccgctact gggaaggagg gccccatctt cgggtgaggt ttttccgacc ggaagaggga
    19501 gtggaagcgt ccatccgcga agcggcggaa acgtttctca aatcccgtcc tcccgcgcgg
    19561 acgctcaccc gggatgcgta ttacgccaac catcgctttg acggcgaacc ggtcgacccc
    19621 gacaccctgc cgtggtatga acacggccag gtggtccgtc tgccctattt cccggagatc
    19681 gaccggtacg gaggaccgga agccatgccg gtcagcgaag atctgttcca cgcttccagc
    19741 gagctggcgg tccgggtcat ggaggcctcc ggcagcctga atgaccgggt ggcccgggcg
    19801 atggacatca tggtggtgac cgccttggca atggaagtga agccggagga actggagacg
    19861 tatttcgacc ggtacgcccg tttctgggag cggttcgtcg atgaccccga ggcctcggaa
    19921 aagcggattc gcgcatcatt tgaacggcag aaggattccc tcgtgcaccg gctgcggctg
    19981 ctgatccgcc tcgtccgggg agaattcacg tacgaactgt tcgcgaactg gctgaacgcg
    20041 ctgaaccggg cccgggaagc gtacgccgac atccaccgaa acggtcgtct ccgcgctccg
    20101 tttccgggtg ctcccgacga tccggctcaa tttttccggg ccgccgtctc aggcatcgcc
    20161 ttttcccaga tccacatgac caacaaccgg ctgggcgttc cgcccgttca cgagcattac
    20221 ctgggcatga tgatttcctt gaccgcggcc gctcaccgcg aggcggaagg agggacctga
    20281 tgggacgcaa accgttcctg accgcttccc tgcaccactt gtccccggaa gaacgaagcc
    20341 ggatgttggg cactcacttt ccggacccgt ttgaaccggc tcttcgctat cacgagtcca
    20401 gcagcttcca tcccgacctg atgtccttcc aggcaccccg gtccgcttac ctgctgccgg
    20461 atcaccgccg gctgcgaacg ggggaaaagt tggaccttcc tccggaggaa tccttgccgc
    20521 cgctgtcggc ttcgctcggc gatgtgattc acaggcgccg ctcccggtac gcgttcggcg
    20581 gagaggtccg cctcgaagaa ctcgccgccc tgctgacggg cggactgggc atcaccgccc
    20641 ggaaagaagt gaaagacggc gccgggcaga catacgtgct gcaattgcgc ggctatccgt
    20701 ccggcggagc gctgtatccg gtggaaacct gggtggtgat gaaccgggtg accggggaag
    20761 gagcgggcgt ctaccgattc agcgcgcccg accgttgtct gtggaaagtg cctgacttgt
    20821 ccctccgtcc ggaagacatc gccgcgtgga cgccgggcac ggatccggac cggaatccgc
    20881 tctattcggc ggaggacttc accgaagccg ccgcctttct gctgctggtc gccgactttt
    20941 cctgtcaggc ggacaaatac gggccccgtg cctaccggct cgcccttctg gaagccggac
    21001 acatggccca aaatctgctg ctcgcggcga cggcgctgga cctgtttgcg gtccccatcg
    21061 ccggctttta cgacggacgg gccaaccagg ccctgaggct ggatccccgc cgtcaggcac
    21121 ttgtctacct catccccgtg ggcagaccga aggaggagag ccaaacccca tgagttcgct
    21181 tgattcatcc cgtgaataca tccgatttcg accgggggtg ttcccctcct ttcccgcctc
    21241 cggccagatt gagcttcgca ccggtccgct gggtcccccg ctcatccgct tgcttctgcc
    21301 ggagggagag gactgggtga gcccgatttt tcgccggttg gacggctccc gaccgattcc
    21361 ggaactattg gacgccatcc ccgaatcgcg cagagcggac gcccgcaaac tgctgagtgt
    21421 tctggtggcg aagagatggg cggaaacggg ggatgcccct ttcaaggcgg aagacccggt
    21481 gaaggaccat ttgctggcgt ttcgttcgtt ttccaacgag gatgcggaac gaaccctgcg
    21541 aaagacgcgt ctgctggtcc tgggcgcggg ccggctgggc agccgcatcg cgggaaatct
    21601 gaccatgacc ggttttcggc aactgacgct tttggacccc tctcccgttt ccttccaaga
    21661 ccggacggct tctcctcttc tgttgcaggc ggaaccggga actccccgcg caaacgcact
    21721 cgcctccgcg ctgcgggaga tggcgccgga cgcagcggta caagccgtga cggaagccga
    21781 cggccggacc ctggagcggg aaatggccga acatgacctg accattgtgg cggaagactg
    21841 ttttcatccc cgcctgctca gcgacgtcaa ccgtctggcg gtccgtttgg ggaagcgctg
    21901 gtccatggtg ctggtgaacg gttggaacct ccatgtcggt cccaccattt ttcccggaca
    21961 atccggttgt ctcctctgcc tgcacctgga aaccggcgag acatgggttc cggaaaacgc
    22021 tcccgaagaa ccggccgccg attccgggga accgacccga tccttggaga gcggattccc
    22081 gtctctcgta tggccgccgc atgccgacgt ggccgccggc cttttggcga cggacatgct
    22141 tcacgccgcc gggatcatgc cccgaagaat cgaaccgggc accgggatga cgctcgggcg
    22201 ccagctggtg tttgacctga aatcgggcca agctttctgg cgaacggtcc cccgcaggcc
    22261 cgattgcccc gtgtgcggac cgggcgccct ttcacatccc catgaatatt gattcttgtt
    22321 cgcagattcg aaaaagttta tcatatgaat gaaaatccct gtgatttttt cccctgtggg
    22381 agaacatgcg gaagcccccg aagagccgac ggactcgtga ttcgaaagat ttgaagacgg
    22441 tttccccgtc cgtgtccacg tcggtcctcg gccggagcgc gaggggggga aattccgacg
    22501 accgggagtg gcacccactc gccaagcatg ttcgggaatg atttgaggat ttgtatgttt
    22561 tcattctgta cccagggatt ctccgaaaaa ttcaggaaaa aggagccgat ccatgacccg
    22621 ggaacaacct gtgattgaag tgcgggaact cagaaaaacg tatggagacg tccgggcggt
    22681 ggacggaatc tcgctggaag tctttcgcgg tgagattttc ggtgtgatcg gagccaacgg
    22741 cgcgggcaaa acgactaccc tggaaatgat gatgggcctt cgcaccccgg actccggcac
    22801 catccgggta ctgggactgg aggttccccg ccaatcctcg gaactgaaac agcgcatcgg
    22861 catccagttg caacagaccg ccctgtatga ccggatcaaa gtgaaagaag cgctcgacgt
    22921 gttcggcgct tactaccggc aacggcggga ccagaaggaa atcatcgatt tgctcggact
    22981 ggagccgtat ctggacaaaa cggtaaaaaa actgtcgggc ggctggcagc aacgggtggc
    23041 cttggccctg gccctgatca acgatccgga gatcatcttc ctggatgaac cgaccaccgg
    23101 actggacccg caggcccgcc acgatctgtg gcagatcatt ctcagtctga aaaacgaagg
    23161 aaaaacgatc ctcctctcca cccactacat ggaagaagca cagcgccatt gcagccgggt
    23221 ggcggtgatc cggcagggaa ggctggtcgc ctgcgacacg cccgccggtc tgatcgcccg
    23281 actgcccgac ggcaacggca cgatggacga cgtctatgtc cagatggccg tcggaccgaa
    23341 aggagagtcc gcctgatgaa agcacttctc gcccacacaa gactggaagt caccctgctg
    23401 ttccgggaag tgatcgccgt ttttttcagc ttccttctgc ccggggcctc ctttgtcatc
    23461 atgggcaaga tcttcggcga ccaggtatac agcaccggaa cgtacttcga aacctacatt
    23521 ccctccatga tgggcatcat cattttcgcc acctgcctgt tcgccgtcgg acttcaggtg
    23581 gtgatcgacc gggaaaaagg cgtttacaag cgactcaaag gcacgccgat caatcccttc
    23641 cacgtgctgg tcgccctgct ggccaaagga ttcatcgcca tctacgtcgg cgtggtggag
    23701 atcctggtgc tggcccgtct ggtgtttgac gtctcgctca cgcctcacct gcttcagttc
    23761 ctgggcgccg tgacctgggc aaccctctct ttcctgggac tcggcttcct gatggtcagc
    23821 gtcacccgtc gcatgcaaac ggcactcgct ttcggcttca tttgcatgta tccgatgatg
    23881 ttcctgtcgg gatccttctt cccgctggac atgatgtccg atttctggaa agacgtggcc
    23941 cagttcaatc cgttgttcca cgccaaccaa ctgatgatcc tcggatacaa gggagacctt
    24001 ttcacacaaa ccggagcgat cagcgcggcc gtcctcggcg gcatcctggt ggtgggctcc
    24061 ggcatcggtt tccggtactt ccgctgggaa ccgtgatgaa cggacgtcga tgtcctgaac
    24121 cggccggaac ccgtggaaag cgaacgggtt ccggtttttc cgttcctcct cacaaaaacc
    24181 ggggatccag cctctctccg agctcctcct tcaactgccg gagcgtctcc ccgtcccgcg
    24241 cggaaacttg taccgtcaaa tactccgtaa tgctcgccac ccatttcccg ccacagaaaa
    24301 acaaaagggg cacgcccttg atcgacgctt gtcccaacag cctcacctcc gcccaagatt
    24361 ccaccgccgc cgcgcgcgca tcgtcccact ccgccggtcc ccgggaaatg atccgggccc
    24421 ccgccaacag gtcctcatac gcttggcacg ccgggccgaa ccattcctca aaccggggat
    24481 gttcctcttt ccagccgggc gcaagatacg catccacccg ccattcccgg gacagatccg
    24541 gcgagaccac cgtgttcccc gaaggaaaca gaaactcccc cgccgtctcc agccaatcga
    24601 aaaacgcctg ctcccaagcg atccattccc ggggggtgaa tgtgggatcg gcggatttgt
    24661 tgttgacggc ttcaaatccc caataaagcg ggctggccac attgatcttc cgattaaact
    24721 gttcttccgg catggtgaag cagatgcggt gcgggcaggg tttcccctct tcgccgttcc
    24781 aggaaaacca gtcgtacggg ctgatttcct tcaagagctg tgatgtgttc agtcgtttca
    24841 agggatgaga cctccgtgtg tttatttgtt gcagagtctg ccgccgtggc tgttcccggc
    24901 gattgccttt gcgccagcaa tgaaatgagc cgggaacggc cacggattcg gatttttagc
    24961 attgtgtgac caagcatacc gaagacaacc cctgcttgtt tcgttgcaat ggcaaaggca
    25021 ctcgcaggga ttggggccgg ctttctcaca aatgcatcac cgccgtgact gttcccggtg
    25081 aatgcctttg cgtcagcaac gaaatgagcc gggaacggcc acggattcgg atttttagca
    25141 ttgtgtgacc aagcatgccg aagacaaccc ctgcttgttt cgttgcaatg gcaaaggcac
    25201 tcgcaggggt tggcttcggc tttctcaaca agccaatacc tctgccgcgt gactgttccc
    25261 ggcgattgcc tttgcatcag caacgaaatg agccgggaac agccacggtt ttccggctgt
    25321 ccagatgctc gccggatgcc aaactcccgc tcgtttcatt gcaatggcaa aggcactcac
    25381 agggattggg gccggctttc tcacaaatgc atcaccaccg tgttcccggt gaatgccttt
    25441 gcgtcagcaa cgaaatgagc cgggaacagc cacggatcaa ggattgacct gtctttgata
    25501 ttcgaggacg aaagaaattt tggggccgat tcaaccgcct tcggtgcgat gtcatgaatg
    25561 cgtcccgttt gaggactcac cgtcgctctt gcaaagaaaa agggaactct cccacccgaa
    25621 agggtgaaga aagttccctc gccaagaaaa gtcgggggca atcagcttca tccggcaaag
    25681 ctttgaatcc tgccgggaga ctgccgaacg gagatagccg ttcactctcc cagcagggcc
    25741 atcagcagcg ccttctgcgc atgcaggcgg ttttccgcct gatcaaacac gaccgagcgg
    25801 gggccgtcga tcacgcccgg ggatacctcc cagtcgcgat aggcgggcaa acagtggagg
    25861 aagaccgcgt cttccttcgc cagcgccatc agggtttcat tcacctgata tccctggaag
    25921 tcgcggaggc gtttctcctt ttcctcttcc tgccccatgc tggcccacac gtcggtgtaa
    25981 acggcgtccg ctccctggac ggcgacgaac gggtcatggc tgaagtgcaa gctgcctccg
    26041 gtgagagcgg ccatttcctc cgcctgtttc cacacctcag gcagcggttc gtaccccggg
    26101 ggcgtggaaa tgtggaggtg aatgcccgcc agcgccgccc cgtgcatcag ggaatgcaac
    26161 acgttgttcc cgtcgccgac atacgtcagc ttcagcccgg acaaggttcc cttcacttcc
    26221 cacagcgtca gcaggtcggc gagaatctgg cacggatggt acaggtcggt cagtccgttg
    26281 atcaccggga tttcggcatg cgtcgccagc tcctccacca gttcctggct gaatgtgcgg
    26341 atcaggatgg cgtccacgta acgggacagg actttcgcgg tgtcctcgac cgattcgccg
    26401 cgccccatct gcaactcttc ccgctgaagg ttgagcgcat ggccgcccag ctgggccatg
    26461 cccacctcga aggacacgcg cgtccgggtg gacggcttgt cgaagatcat ggccagggtt
    26521 ttccccttga gcggagcgcc gatgctccag agttgccgct gggttttcat ctggtgggcc
    26581 agttccacca gcgattgaag tccggagggg gaaagaccct ccagcgtgag aaaatcctgc
    26641 cccttgagcg gggccaatgc cggtttggac aagagtgcgt tcatttggcg acaacctccc
    26701 tgatctcgct caatccttcc attttccctc cgaaccgctt ttcggccacc tgcccgatga
    26761 tccggaccgc ctgccggatc tccgtttcgc cgaccaccag gggagggagc aggcgcagca
    26821 ccgtttcccc cgccggaagc gtgaccagtc ccgcatgcag cagctcccgg atgaagggct
    26881 gaaccggaac ggtgagctcc acgccgatca tcagcccgag accgcggaca tcgatcactt
    26941 ccgcgtacgg agacagcact tggcgcaatc cgtccctcag caaccggctt ttcgcttcca
    27001 cttccccgat cagtcccgac acctccaact cctccagcac cgctcccgcc gccgccatgg
    27061 ccagcaagtt tccgccgaag gtggttccgt gcgaaccggg tcccaaatgc ggcttcaatt
    27121 cctctcgggc cagcatggcg cccacgggga atccgttgcc gagtcccttg gccgtcgtga
    27181 tcacgtccgg ggtgatgccg tatcgttgaa aggcaaacca tgcgccggtt cttccgatgc
    27241 cggtctgcac ttcatccacc atcaggagca accgtttctc gcggcaccag tcggccagct
    27301 cccggacaaa cccgggatcg acgggtttca cgccgccctc cccccgtacc aactccaaca
    27361 gcaccgccgc ggtggccgct ccggtggctt cccgcaccgc gtccatgttc tccggcggca
    27421 gaatgcggaa tccgcccgga agcgggtcga atccccgttt caccttctcc tgaccggtgg
    27481 cggtgagggt ggccaacgtc cgcccgtgaa acgatccctc aaacgtcaga atctgcggtt
    27541 cggcaatcac cttggcttcc cgggcccagc ggcgggccag cttgatggcc gcctcattgg
    27601 cctccgcgcc gctgttgcag aagaacaccg ctcccatccc cgacacccgg caaagggctt
    27661 ccgccacccg ttcctgaagc ctgtggggaa agagattgga caggtgccaa agctgcccgg
    27721 cctgccggat cagggctgcc cgcacgcggg gatgattgtg tcccagtccg gtcaccccga
    27781 ttccggaagc gaaatccagc catcgccgtc ccgaccggtc agtcagccag acgccttctc
    27841 ctttttcgaa ctccacatca taccggatgt aagtgggaaa cagcttcacc cgtcttcacc
    27901 tcttccctca ccaggcaggt gcccgttcct tcctctccgg ggagaaccgg ggacttgccg
    27961 cccgtgatcc acacctcttc caccgacccg cgcaggcagc ggatgcccgc acgcgttttg
    28021 ggaatcatcc ctcccgtgat ccagccgttc cggatgcctt cttccagctg ctgcaacgtg
    28081 gccttggaca accggatgcg tttggcccct tcggtgcggt aaatgccgtc gacgtccgtc
    28141 accagtacga gacgtttggc cgagatcgat tccgccagcg cggcggccgc ctcgtccgca
    28201 ttgatgttgt agtgtcggcc ctgttgatcc gccccgacgg aagcgatcac cggcacccat
    28261 ccgtccgcga gcatgctgcg gagggcttcc cggttcacct cttccacctc gccgacaaat
    28321 cccaatcggg catcggccgg tttgacccgc aggagggaga gatccacccc gctcagcccg
    28381 attgccggaa tgcccgccat caagagcgtc gacaccaacc gcttgttgat atctccggcc
    28441 agcaccatcc tggccgcttc gagggtttgt tcatcggtga cccggcggcc gtcgacgaaa
    28501 cgggggacga tgcccctctc ccgcaggaat tccgacaggc gcggaccacc gccgtgcacc
    28561 acgaccagcg gtgtgccttc ggcatgcaaa cgggcgattt gttcgagaaa ccgggattcc
    28621 atccggtcca tcgcgtgtcc tcccagtttc accacgaccg ctttctccac gacttccctt
    28681 ccctcctcat gtgcggtaac tcgcattgat ggtcacgtaa tcatgggtca gatcgcatcc
    28741 ccacgccacg gcctttccct ccccggagtg gagcttcaga cggatgcaca ccgtctcccg
    28801 ccccagttcc gcctcggcgg ctccggcgtc aaacaccagc gggattcctc cgcgcaccac
    28861 ctgaacgtct ccgagaaaca cttccgtctt ctccggatcg agcgtgggat ccccgtatcc
    28921 ggccgcacac acgatccggc cccagttggc atccctgccg aacaccgccg ttttcaccag
    28981 gctggatccg gccaccgccc gcgcgacggc cgcggctctc tttgcgtcgg acgctccttc
    29041 cacctgcact tcgatcaggc gggtggcacc ttccccgtcc ctggcgattg ccttggacag
    29101 ctcccggcac acatgaagaa acgccgcgga aaacgcctcc caatcgggat ggtcgggagt
    29161 gagagtccga ttgcccgcca gtccgctggc catcgccacc gtcatgtcgt tggtgctgga
    29221 atccccgtcg accgtgatca tgttgaacgt ttcgtccgtt gctttccaca gcagcgactg
    29281 aagcatgtcg ggggaaatcc gcgcatcggt cgtgatgaag gcgagcatgg tggccatgtt
    29341 gggatgaatc atgccggacc ctttggccgc ccccgccacc accaccggga ctccgtccac
    29401 cgtcagcctg acttcggcct gtttgataca ggtgtcggtg gtcaggatcg ctttggcgaa
    29461 cgaacgtcct ccttccttgc tcaccgtcag ctgccggagt ccgccgacaa tccggtccat
    29521 cggcaggaat tccccgatca cgccggtgga ggccaccgcc acttcatgcc ggttcactcc
    29581 cagaagctcc gccgccgtat cccgcatcat ccgggcatct tccaaaccgc gaggaccggt
    29641 gcatgaattg gcgttcccgc tgttgaccac cacggcccgc agggttccgc cggcgccaag
    29701 actttcctgg gtcaccttga tgggagccgc ctgaaaggca ttggtggtgt acacggccgc
    29761 cgcactggcc ggccgttcgc aaacgatcat gcccagatcc ggtcgctttc tcttgatccc
    29821 gcaatgcatg cctccggccg caaacccttt cggcgatgcg acattgggtt cattcacgat
    29881 gacaaacggc gttttcccga tcaggatccc ttgttccacg tccgttccct cctctccgga
    29941 acattcctgt acgcgcttgc tctcacgggt attggggaag tgccttcagt ccggtttcct
    30001 cggaccaccc cagccggatg ttggcatttt gcatcgcctg accggcggct cctttcatca
    30061 gattgtcgat cgccgccatg aggatcaccc gccccgtccg ctcgtcgacc cgcacggcga
    30121 tgtcacaaaa attgctgcct cgcacggcac cggtttccgg cggacggtcc gtcaggatcc
    30181 ggatgaacgg tttgtcccga tacgcgtccc gatacaggtc ggtcagttcc ttttctgtat
    30241 atttattcat caatgatgca taaacggtga ccaagattcc gcggttcatg ggaaccaggt
    30301 gaggaacaaa actgatgcga agctcccgtc cggcaaagcg cgccgcccct tcttcgatct
    30361 ccgtcgtgtg agggtgaccc gtcacccggt aaggcctgag gttttcattc acctcgcaat
    30421 acagcagttc ccgcttcaga ccgcggccgg caccggtcac gcccgacttg gcgtcgacga
    30481 tcaccccggc cggattcacg atcccttccc tcagaagcgg aaggagcgca aggagcgtcg
    30541 cggtcggata acaacccgga ttggcgatca gttccgcctc ccgaagtcgc tcccggttcc
    30601 attccgacaa tccgtacacg gcgcgttcca accattcttt cggcgccggc ggcttgccgt
    30661 accgctcctc atacacggcc ggatcgtgaa accggaaatc ggccgacaga tcgatcacga
    30721 tgcagcccgc ctcaaggaac ggggccgccc atcgggcgca gattcccgga ggagtggcga
    30781 aaaagaccag atccgccttc cggcacaccc gctccggatc gagctcttcg tacatccgtc
    30841 ccaggtggga cagagagagc caggaagtgc ccagttcctc ccccgcctgg gaagtggaaa
    30901 ccgccgccga caactccagc tccggatgcc cttcgatcag ccggatcagt tccgcccctc
    30961 cgtatcccgt tgaaccgatc accgccgctt tcatgctcat tccctcctcg atatgcatca
    31021 ttatacattc gagttcatat ttattcaaca cttttttccc gtttcgtttt cgccggggaa
    31081 acggaagatt ccggaaatga acggcgactc catccagcct ccgcgatgaa atgcattttc
    31141 ccatgccagg cgagaaagcc ggatcattcc cgc
//
