LOCUS       NZ_CP034118            27381 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Staphylospora marina strain SCSIO 07575 chromosome, complete genome.
ACCESSION   NZ_CP034118
VERSION     NZ_CP034118.1
KEYWORDS    RefSeq.
SOURCE      Staphylospora marina
  ORGANISM  Staphylospora marina
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Staphylospora.
REFERENCE   1  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Staphylospora marinus gen. nov., sp. nov., a novel member of the
            family Thermoactinomycetaceae, isolated from a deep-sea hydrothermal
            vent sediment in Pacific Ocean
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2018) CAS Key Laboratory of Tropical Marine
            Bio-Resources and Ecology, South China Sea Institute of Oceanology,
            No. 164 West Xin Gang Road, Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: FALCON v. 0.3.0; Celera Assembler v. 8.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1382.0x
            Sequencing Technology             :: PacBio Sequel; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003856495.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 03:57:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,772
            CDSs (total)                      :: 2,679
            Genes (coding)                    :: 2,660
            CDSs (with protein)               :: 2,660
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 6, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 4 of 19
            Pseudo Genes (incomplete)         :: 16 of 19
            Pseudo Genes (internal stop)      :: 0 of 19
            Pseudo Genes (multiple problems)  :: 1 of 19
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1250698
            Orig. end                         :: 1278079
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034118.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27381
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..27381
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27381
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17381]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17381
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            274..1116
                     /locus_tag="EG886_RS06240"
     CDS             274..1116
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014658.4"
                     /locus_tag="EG886_RS06240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="menaquinone biosynthesis protein"
                     /protein_id="WP_124727327.1"
                     /transl_table=11
                     /translation="MTVRVGKISFTNVLPIYQHLDATGLDIELVPEVPARLNKAMAEGG
                     IDLSPISSFAFGARHRDFYLLPDLSVSAWGDVRSVCLFTKGKSLSELDGARVALTPKSA
                     SSVALLRILLERYEGVKPRYETMEPDLPRMLESADAALLIGDDAIVGGRAHPEYRVFDL
                     GREWHERTGHSMTFAVWAVRREVAHRSPNELANIHERFLEAKESGKRDLRPAVHEAMRL
                     LGGDEGCWERYFRGLTYDLGERELEGLKLFFRHCAELSLLPEDVEICMPDLGAGTGMR"
     gene            1131..2102
                     /locus_tag="EG886_RS06245"
     CDS             1131..2102
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PT_FPPS_like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PT_HPP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708529.1"
                     /locus_tag="EG886_RS06245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_124727328.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.9e-59, bitscore:
                     197.4, seeds: 145, tool: rule-based-clusters)"
                     /sec_met_domain="PT_HPP (E-value: 6.5e-68, bitscore: 226.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLQDIYLNLKKDLEIVEQALARSVEADVAVLRDASLHLLKSGGK
                     RMRPVFVLLSGHFGRYEVERLCRAAVALEMIHMATLVHDDVIDDADTRRGRKTVKAEWD
                     NRVAMYAGDWLFARALRELADLGDHRVQVILAEAMRLMCLGEIEQIEDLYAERLSLRRY
                     LRRIKRKTALLMSISCHLGALVAGASEEHIRLLRAYGYYVGMAFQLTDDVLDLTGDERI
                     LGKPAGSDLKQGNVTLPVLHVLHTGTADHRQKILDFLRSQGMADNLGEVLDIVRGGGGV
                     EATLELSRRYLNKAIDCLNRLPDSHQRESLRLIAEFIVRRNY"
     misc_feature    1150..1164
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.44"
                     /tool="antismash"
     misc_feature    complement(1180..1195)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.89"
                     /tool="antismash"
     gene            2199..2642
                     /gene="ndk"
                     /locus_tag="EG886_RS06250"
     CDS             2199..2642
                     /EC_number="2.7.4.6"
                     /GO_function="GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="ndk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003387082.1"
                     /locus_tag="EG886_RS06250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_124727329.1"
                     /transl_table=11
                     /translation="MEKTFIMVKPDGVQRGLIGEVVSRFEKKGWQLVGAKFMTVSRELA
                     EKHYAEHKEKPFFGELVDFITSGPVFAMVWQGHNVIAGARQMMGKTNPADAAPGTIRGD
                     FGVNVAMNIVHGSDSPESAEREIALWFGNEELVNWEKTINKWI"
     gene            complement(2711..3670)
                     /locus_tag="EG886_RS06255"
     CDS             complement(2711..3670)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009709805.1"
                     /locus_tag="EG886_RS06255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_124727330.1"
                     /transl_table=11
                     /translation="MIRFLRLVQNENMKIWRRLSTPVMCGILAAACILMAFVMKAYQPA
                     EAPADPWKQSLLLENEQLAESLSKGQLPPAMAEETRKKMEINEYRLQKNLPPHEPLMWK
                     FTRETGTLLIPLVTLFTVITGATAVAGEFSMGTIKFLLIRPPGRSQILLAKYLSILLFA
                     LGLLLLLFVLLPLVGGVMFGFESWGPPRLIHDGQQIIERSVPAHLLILFAGSTAELLMM
                     VTFAFMISTVFRSSSAAIGLSVFLMFAGHQAVNILSLRGADWIRWILFANTDLLPYFGE
                     GSPPAEGMTLAFSLTVLVVHFLLFTGISWWVFARRDVA"
     gene            complement(3667..4593)
                     /locus_tag="EG886_RS06260"
     CDS             complement(3667..4593)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010678244.1"
                     /locus_tag="EG886_RS06260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124727331.1"
                     /transl_table=11
                     /translation="MPTPVLTVRNLTKKIGDKVIVNRLHLDLYPGEIFGFLGPNGAGKT
                     TVIRLITGLMSPTEGDIFIDGHNLKTHRALALSRVGAIVENPEFYPFLSGYHNLLHYAR
                     MSDHVSRDRIREVVRMVGLGDSIDDKVKTYSLGMRQRLGIAQALLHSPKILILDEPTNG
                     LDPAGIRNLRDDLRRLVREENLSILVSSHILAEMEAMCDRFGILKQGEWIEERRLNDWR
                     GNHEEHERTVFFFADPLPSAEQILRTLFPERTVHVEDDRLRISLKYEQIPEANAELVKS
                     GIRVYEIRTENISLEDRYLSLTGGVGA"
     gene            complement(4680..5420)
                     /locus_tag="EG886_RS06265"
     CDS             complement(4680..5420)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="EG886_RS06265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_164491688.1"
                     /transl_table=11
                     /translation="MTGILQAEWIKLRRSKIWLLLVILPSLPILYTLFIYVGIMIGKYR
                     FEADNLWFMPWAMSIMFYGGIFYPILSAMVATSLCRFEQTGNGWKQLFTFPVPRHQLFF
                     GKLIWLYALLLFAQIFALALFVAVGKILGLDGPVPWGTLFISAMSGWVGALPLAAIQYS
                     LALWMEGFVKPMISNVALTVPVFLIISSELKSSSVTLYPWALPAIGMMQGGTTGVSGMF
                     LTVVPVVLFLAIFIGLTYFRRKSV"
     gene            complement(5464..6180)
                     /locus_tag="EG886_RS06270"
     CDS             complement(5464..6180)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.4"
                     /locus_tag="EG886_RS06270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_124727333.1"
                     /transl_table=11
                     /translation="MMNVLSTEWIKNRRTSVWLLTCLIPAGLWGFLTVMIWYMFETGRP
                     PEKVWAIAMETLSLFLGPVLFMGVPLFTAQTAQIEHQTGMWKQLLAMPVPKWQLYAGKF
                     LWNFLFIQLSGLLMTLLLAGSVIMWNLGNEVSLRSLFLHGWVPFLLTTPLIAFHTWLSQ
                     VFEHQGVSTGAGAAGMILGPLFKEAGWWTPWGYLTTFMPGYGLPFQDSRVWLTGAVLTL
                     VLLMAGGAHFFRWMSR"
     gene            complement(6177..7100)
                     /locus_tag="EG886_RS06275"
     CDS             complement(6177..7100)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003389575.1"
                     /locus_tag="EG886_RS06275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124727334.1"
                     /transl_table=11
                     /translation="MEEALIKTDELTKVYNRQRVVDGLNLEVRRGTIYGFLGPNGAGKT
                     TTIRMLLGLVRPTGGTVHMFGQEFSNNRLSILKRVGSLVETPSYYGQLTGYENLEVARK
                     LYRIPDKNRIDEALSLVGLEDARNKKVKQYSLGMKQRLGLATALLNNPDLLILDEPTNG
                     LDPAGIREMRDLIKRLPRERGVTILLSSHLLSEVEQIADDVGIIHKGKLLFQGSLESLR
                     KHTRSRTVIEVDRPEDAAKLLKEHGFSVHLEEGLLVLPTSEAENTLREIQRLLVQDGFI
                     IRRLEEERPPLENIFLNLVEAGDSPS"
     gene            complement(7122..7424)
                     /locus_tag="EG886_RS06280"
     CDS             complement(7122..7424)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS06280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124727335.1"
                     /transl_table=11
                     /translation="MSGAVLLKSLTAVSSVWMIFSLVVIAYFYQKEGKDERGELIFNKF
                     FRFMFFLLSVCIAWLVFLAARFDFPYELYRRIIELSLCLTYVVGTVRLLVLRKRY"
     gene            complement(7421..7636)
                     /locus_tag="EG886_RS06285"
     CDS             complement(7421..7636)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019394286.1"
                     /locus_tag="EG886_RS06285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_124728696.1"
                     /transl_table=11
                     /translation="MLRNRLTVLRAEKGWTQQEVANRLGISRQTVHSVENNKFVPSVLL
                     AFRIARLFGKNVEDIFQYEEEGEDSQ"
     misc_feature    7636..7651
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    7689..7704
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.09"
                     /tool="antismash"
     gene            complement(7785..10004)
                     /locus_tag="EG886_RS06290"
     CDS             complement(7785..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067397.1"
                     /locus_tag="EG886_RS06290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_241154397.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 8.1e-42, bitscore:
                     139.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRRKRLFTRRRVPFIEQMQQTECGLCCIAMIAAYYKSSVSLYEL
                     RERMGGGRDGTTLFHLRNLAEQLGFETKCYRLDASSLRQLPLPAVLFWNDKHYVVLESV
                     TKKHFVIVDPAIGRRRLSPEAFMRSYSGVVMQLCPGEHFVRQKGQSVWKPFLASLREHP
                     GLFVSILAISLLLQLFAVGIPMLIQFVVDQIITPKQYDLLNMFLVGIGMLVLFQTVFTF
                     IRGKCLIILHNRLDHGMMTRFFTHLLRLPYQFFQLHSFGDLHFRANSHRVIRDILSNQL
                     IKGILDLGILIVMLLYMTLVSPLMAGWVAAMAGLNVFVLGWYRSRITEANQEEINRQAL
                     VQGSQAEMLYGIFGVKTSGIERMMYNQWYERFRDLLGAYRAKENLLNHVNTATGFLSLL
                     APLSVLWIGVHMIVSEQLTLGGMIAFYSISNQFFGLSSSIVNTVNSFFLTESFLRRIQD
                     VLDAKEEPVCENPIRLSSLRGEIELQNVSFAYTKFSPPAVKNVSLKILPGQKVALVGKS
                     GSGKSTLARLILGLYVPTEGRILFDGHDLKTLDKQALRKHIGAVPQDDMLFNRTILENL
                     TLLKPDASMEEVTEAAKIAQIHDEIMEMPMNYHTMISELGMNISGGQRQRITLARALVH
                     KPSVLLLDEATSSLDHVNEEKIDRVLSDMKCTRIVITHRLTTIRNADLILVLEDGRITE
                     QGTHDELMRKNGFYRRFYEKDLKKPEVTGSSVRNPEADAAVGTHP"
     gene            complement(10001..13147)
                     /locus_tag="EG886_RS06295"
     CDS             complement(10001..13147)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="EG886_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_124727336.1"
                     /sec_met_domain="DUF4135 (E-value: 1.3e-108, bitscore:
                     360.8, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-68, bitscore:
                     226.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKASVEQPAWLRGTFLSERKQPMHADPARGEERFRNWLRSGDFTE
                     NTLRERLERDGLTLGEFRDILGDPDFPEIRNDPAWISRLTEILRENEQVPARDMENQIP
                     FSPFYHPFVHHVRQSLNRLLQELEHSCECRNWFDPDALLESMLETVCRRLSALGIKTLI
                     TELHVMKATGQLSGDTPEQRYLDFANRLGTPSFRNRVLETYPVLARLLTQTVTQAIETH
                     EESLRRFLKDRDDILRTFNGRFSKLVGIRSGAGDTHQNGRSVSIFQFESGEKLVYKPRS
                     MAVDVHYGELLSWINGKGFSRPLLPAKALDKGTHGWQEYVEHTDCRSKEEARNFYYRQG
                     GYAALLYLLRSSDFHAENVIAHGEHPVLIDLETLFSQRFEILSSRISIPKVLDELNNSV
                     FGSMLIPLKLANNPYLDLDLSAIGGKQGQESKTLKIRTVHKPGTDEMRLVEVPARSPGH
                     RNRPTLGGEELDPAEYSREIEEGFREMYSLFLTHRDELLSETGPIHRFAGDQVRHIFRP
                     TQTYSRFLDASVHPDYLQDGLDRNRLFEFFWRTVSVIPRYGQMIPMETDDLLQHDIPYF
                     SFRMNGRSLFDSRGREIRDFFERTCLDQVLERCRELDPADCEKQCGYIRMSMATLVHDA
                     QVTETGNDSSSEQKAPIRPASREQLLEAAKEIGHELLQRAIWSDDRKEAYWLGLTPGEE
                     SLQIAALESGLYDGTMGIILFLAQLGQETGDETWTRLAKAALSGTFTLLRGKPLPVSAF
                     SGLTSLAYGLSYLGLLWKDQELLEKAFDRLPSIPNALEADRHFDLIGGAAGALLVCLRL
                     HKIRPSSSALDMAVKCGVHLLRHVRIGEDDSGGWLTGLSHGAAGYAWAWTELAAVTGES
                     RFALAAERALAYERKHFIAREKNWMDLRETGDVRNHPVYWCHGAPGIGISRLKMANVSG
                     DPLLKEEWSIAVEKTLESGFGGNHSLCHGDFGNLDFLLLSAGIPGHEHLRVTCAEIGTR
                     SLRRGLDDGWKFGYHKNPEAELLGLMLGLSGIGYGLLRLVNPSIPSVLALELPEGEMIG
                     "
     gene            complement(13273..13491)
                     /locus_tag="EG886_RS06300"
     CDS             complement(13273..13491)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="EG886_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_124727337.1"
                     /transl_table=11
                     /translation="MSMQERALRDPKLRFEGFEHPAGMVNEDELMNIVGAGEVRPQSGP
                     VCAVTLAVCVPVSLAFCPTTACTSDCR"
     CDS_motif       complement(13384..13491)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSMQERALRDPKLRFEGFEHPAGMVNEDELMNIVGA"
                     /locus_tag="EG886_RS06300_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13273..13383)
                     /prepeptide="core"
                     /locus_tag="EG886_RS06300_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.80"
                     /molecular_weight="3513.1"
                     /monoisotopic_mass="3510.7"
                     /core_sequence="GEVRPQSGPVCAVTLAVCVPVSLAFCPTTACTSDCR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSMQERALRDPKLRFEGFEHPAGMVNEDELMNIVGA"
                     /leader_location="[13383:13491](-)"
                     /alternative_weights="3531.1"
                     /alternative_weights="3549.1"
     misc_feature    13554..13571
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     CDS             complement(13594..13701)
                     /gene="allorf_1264292_1264399"
                     /locus_tag="allorf_1264292_1264399"
                     /protein_id="allorf_1264292_1264399"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTNTPLLQDCFGANKDYYISKNYFKEFRVYLHFCV"
     CDS_motif       complement(13663..13701)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTNTPLLQDCFGA"
                     /locus_tag="allorf_1264292_1264399_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13594..13662)
                     /prepeptide="core"
                     /locus_tag="allorf_1264292_1264399_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.70"
                     /molecular_weight="2859.3"
                     /monoisotopic_mass="2857.4"
                     /core_sequence="NKDYYISKNYFKEFRVYLHFCV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTNTPLLQDCFGA"
                     /leader_location="[13662:13701](-)"
     misc_feature    13636..13649
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            13700..13921
                     /locus_tag="EG886_RS06305"
     CDS             13700..13921
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="EG886_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_206425350.1"
                     /sec_met_domain="mature_ha (E-value: 3e-10, bitscore: 36.9,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSREIRMWKDPVFRLQSEGSMMEHPSGNVMEELREQDLLSVAGGC
                     DWWNISCHLGNTGRFCTLTKECQPNCNY"
     CDS_motif       13700..13831
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSREIRMWKDPVFRLQSEGSMMEHPSGNVMEELREQDLLSVAGG"
                     /locus_tag="EG886_RS06305_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13832..13921
                     /prepeptide="core"
                     /locus_tag="EG886_RS06305_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.60"
                     /molecular_weight="3335.7"
                     /monoisotopic_mass="3333.4"
                     /core_sequence="CDWWNISCHLGNTGRFCTLTKECQPNCNY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSREIRMWKDPVFRLQSEGSMMEHPSGNVMEELREQDLLSV
                     AGG"
                     /leader_location="[13699:13831](+)"
     gene            13939..14160
                     /locus_tag="EG886_RS06310"
     CDS             13939..14160
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="EG886_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_124727338.1"
                     /sec_met_domain="mature_ha (E-value: 1.4e-10, bitscore:
                     38.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQLVRSWKDPLFRVQTEQNRMEHPSGNVLEELREQDLLSVAGGC
                     DWWNISCHLGNTGQFCTLTKECQPSCNR"
     CDS_motif       13939..14070
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNQLVRSWKDPLFRVQTEQNRMEHPSGNVLEELREQDLLSVAGG"
                     /locus_tag="EG886_RS06310_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       14071..14160
                     /prepeptide="core"
                     /locus_tag="EG886_RS06310_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.60"
                     /molecular_weight="3255.6"
                     /monoisotopic_mass="3253.4"
                     /core_sequence="CDWWNISCHLGNTGQFCTLTKECQPSCNR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNQLVRSWKDPLFRVQTEQNRMEHPSGNVLEELREQDLLSV
                     AGG"
                     /leader_location="[13938:14070](+)"
     gene            14232..17381
                     /locus_tag="EG886_RS06315"
     CDS             14232..17381
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="EG886_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_164491689.1"
                     /sec_met_domain="DUF4135 (E-value: 7.1e-116, bitscore:
                     384.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-74, bitscore:
                     247.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDATRWIRAFYMDERIASRPVDPDAFSQRMKYWEMLTGGSREKLE
                     TCIQGVSGFPVDRLAGLAGAEAIRQEAVAEDTWFPGFQKWLSGAYDRVVLPPETGTDIP
                     FFGFFEPFLKLGLGALHERFPHANRLSQPVVRSLLGQLAHRLFEVAHATLILELNVARV
                     SEKLSGDTPEERYRHFSEVLLRDEQTRLSLYNEYPVLVRLAVTKTLHWVSHVSELLERI
                     EADRDLLSQRFHSGHDIGVPEEIDLGLGDSHNKGRGVAMVRFSGGLRVIYKPRPMGVDI
                     GFQDLLRWLNREMAGEEPFRILNVVDRKTYGWSEFVEKLDCRTEEELVRFYRRMGRLLA
                     LLYLLQAVDFHHENLIAHGEHPVLVDLESLFHQTLGRKEYTGNATDRAEEILQRSVRST
                     GLLPAPLYYRGNPGAGGVDVSGIGAGGEQTAPFKLPYIENKNTDRMRMVNDYGKISAAN
                     NRPTLRGSEVKLSVYLPVLEQGFEEMYRWVMEHGESFKERLYRFSDVQVRSILRSTMQY
                     GNLLRQSVHPDFLRDGIDRDVLLHRLWLDTDTMPSLKAVVRSEKRDLTEGDIPFFHTRP
                     GERHVRDSEGRRLDCEFPVSALEDVFQKIDALSPEDCRNQLQVVRMSILAGEARHDADV
                     AAVDPRMKVPGPLPEKDEFLREAEKIGDYLLSKAISGFDEETGEEDATWISTTLEGTGE
                     ILWQISPVGNDLYNGNSGIALFLAFLSELTGRSDFREAAAKALVPVRKAVRKFGEHPGW
                     SIGPFNGAGGYLHAMNLLAALWKDEALRNEVERGLDGFLKMIPQDRLYDFIGGSAGALF
                     VLLGIHRRTGNRLALEGAGLCAEHLLKHAERAETGIGWRLPWEKAPYTGFAHGVSGVAC
                     ALFEWYRLSGDDRFKEAVSQALEYERSFFDEAAGNWKTPGRDTPSVAWCHGAPGILLGR
                     LMLKRSGFEDERLEEELGIALETTLNRGFGNNRSLCHGDFGQIGILRFASEVLGDGRLS
                     QWADSAAAQVLNVIREQGFRCGVSRGVEAAGLMVGLAGIGYGLMMQSAPSRIPFILRLE
                     S"
     gene            complement(17457..17759)
                     /locus_tag="EG886_RS06320"
     CDS             complement(17457..17759)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016078316.1"
                     /locus_tag="EG886_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_124727340.1"
                     /transl_table=11
                     /translation="MELKALTPEEKQVAILIASGLRDKEIGARLYISKRLVCKRIQSIK
                     KKWSVQSRVSIGIMVCHLGWYDCSEKARVISSQWAKNKHGASGTNFRHPRVGKDA"
     gene            18081..18314
                     /locus_tag="EG886_RS06325"
     CDS             18081..18314
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003201510.1"
                     /locus_tag="EG886_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_124727341.1"
                     /transl_table=11
                     /translation="MKLTAREREVALLVACGYTDTEIAEELGVSRRRICEIVSSIKFKW
                     KTRSRVEIGIIVYYLGWIKEELSGKDLLSALR"
     CDS_motif       18081..18167
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKLTAREREVALLVACGYTDTEIAEELGV"
                     /locus_tag="EG886_RS06325_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       18168..18314
                     /prepeptide="core"
                     /locus_tag="EG886_RS06325_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="5571.6"
                     /monoisotopic_mass="5568.2"
                     /core_sequence="SRRRICEIVSSIKFKWKTRSRVEIGIIVYYLGWIKEELSGKDL
                     LSALR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKLTAREREVALLVACGYTDTEIAEELGV"
                     /leader_location="[18080:18167](+)"
                     /alternative_weights="5589.6"
                     /alternative_weights="5607.6"
                     /alternative_weights="5625.6"
                     /alternative_weights="5643.6"
                     /alternative_weights="5661.7"
                     /alternative_weights="5679.7"
     misc_feature    18348..18359
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.48"
                     /tool="antismash"
     gene            18631..19794
                     /gene="aroC"
                     /locus_tag="EG886_RS06330"
     CDS             18631..19794
                     /EC_number="4.2.3.5"
                     /GO_function="GO:0004107 - chorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013144894.1"
                     /locus_tag="EG886_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chorismate synthase"
                     /protein_id="WP_124727342.1"
                     /transl_table=11
                     /translation="MRYMTAGESHGPQLTVIIEGLPAGLVFEKEKIDHQLVRRQKGYGR
                     GRRMQIERDGVQILSGVRFGRTTGAPVTLVIENRDFSHWKKVMSVNPIPEEAEKRRISR
                     PRPGHADLNGAIKYGHRDMRDVLERSSARETAARVAAGAVARLILEECGIGLAGHVVRI
                     GEIGAKPVQGLTLDQIRERSEASPVRCLDPEAERLMMERIDRAKVEGDSLGGIVETIVE
                     GVPVGLGSHVHWDRKLDARIARAVVSINAFKGVEFGMGFEMASRPGSEVHDEIIWSPET
                     GYSRRTNRMGGFEGGMTTGMPIVVRGVMKPIPTLYKPLMSVDIDTRRPFAASIERSDSC
                     AVPAASVVMEHVVAWEVAVALMEKFPADTMEELTDHVRRYRERVREF"
     gene            19798..20895
                     /gene="aroB"
                     /locus_tag="EG886_RS06335"
     CDS             19798..20895
                     /EC_number="4.2.3.4"
                     /GO_function="GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017687708.1"
                     /locus_tag="EG886_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-dehydroquinate synthase"
                     /protein_id="WP_124727343.1"
                     /sec_met_domain="Fe-ADH (E-value: 4.3e-08, bitscore: 29.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 9.9e-99, bitscore:
                     327.0, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLTIATTSRTYPLTVGSGVLQRLPELLEQVGVGTERRLMVVTD
                     ERVGPLYAEPVLKRLIRSGYRAGLSVIPSGEASKRLAVLESVIGECLRFGLDRRGVILA
                     LGGGVVGDLAGFAAAVYMRGIDFVQLPTTLLAHDSSVGGKTGVNHPMGKNLIGAFHQPL
                     AVVYDVDTLRTLPKREVRSGLAEVIKHGLIRDQAFVTWLESFREPLLRLEPDAVTEAVW
                     QGCRIKADVVAADERESGLRAILNYGHTIGHALEAVTHYGAYTHGEAVAIGMAGAARLG
                     GKVLGTRDDVVRRTEELLLSYGLPVRHRWSGPDTELLSVMKRDKKSLDGGFAFVLTREI
                     GRAELIRDVPEDAVREVLTQLREGT"
     CDS             complement(21054..21263)
                     /gene="allorf_1271752_1271961"
                     /locus_tag="allorf_1271752_1271961"
                     /protein_id="allorf_1271752_1271961"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPAPADVVHASRLFSARLRVPFSAPLISAQHSVGRKKDLSLTLIA
                     HETSCTLRSLRRQARASRRLTPLG"
     CDS_motif       complement(21231..21263)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPAPADVVHAS"
                     /locus_tag="allorf_1271752_1271961_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(21054..21230)
                     /prepeptide="core"
                     /locus_tag="allorf_1271752_1271961_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.50"
                     /molecular_weight="6281.3"
                     /monoisotopic_mass="6277.7"
                     /core_sequence="RLFSARLRVPFSAPLISAQHSVGRKKDLSLTLIAHETSCTLRS
                     LRRQARASRRLTPLG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPAPADVVHAS"
                     /leader_location="[21230:21263](-)"
                     /alternative_weights="6299.3"
                     /alternative_weights="6317.3"
                     /alternative_weights="6335.4"
                     /alternative_weights="6353.4"
                     /alternative_weights="6371.4"
                     /alternative_weights="6389.4"
                     /alternative_weights="6407.4"
                     /alternative_weights="6425.5"
                     /alternative_weights="6443.5"
                     /alternative_weights="6461.5"
                     /alternative_weights="6479.5"
     CDS             21080..21142
                     /gene="allorf_1271778_1271840"
                     /locus_tag="allorf_1271778_1271840"
                     /protein_id="allorf_1271778_1271840"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHGLAGGVSGVCTKFRARSE"
     CDS_motif       21080..21100
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHGLAGG"
                     /locus_tag="allorf_1271778_1271840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       21101..21142
                     /prepeptide="core"
                     /locus_tag="allorf_1271778_1271840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1385.6"
                     /monoisotopic_mass="1384.7"
                     /core_sequence="VSGVCTKFRARSE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHGLAGG"
                     /leader_location="[21079:21100](+)"
                     /alternative_weights="1403.6"
                     /alternative_weights="1421.6"
     misc_feature    complement(21238..21252)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.93"
                     /tool="antismash"
     gene            21344..22852
                     /locus_tag="EG886_RS06340"
     CDS             21344..22852
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012640.4"
                     /locus_tag="EG886_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate synthase component I family protein"
                     /protein_id="WP_164491690.1"
                     /transl_table=11
                     /translation="MRAVLSPEEVFRLSRRFSCIPVMIETDAAEETPIRLYARMSRKHG
                     SFLLIKQRFAWIADDPVRCMRSHRGSWFLRDGQGRILPVTDPDPFVWLKKELERNRFPR
                     LSGCPPLAGGMAGWIGFGSVRFLEPNRPVTRHPNEDPDICLMRFDRMSVMDQKRGKLWF
                     TEVLKIPDGIGKSEMFALYGQAVQRLMTWAGELLSRPVRLSEPAFDMEFPVRETDVCGW
                     TEETDPHAFHESVRQVKERIASGDVFQVVLSRSWSRPRMADPLDVLRVLERINPSPYLF
                     LMETEEESLVGASPETLVRVTDGRAEVHPIAGTRPRGSTPAEDERLAAELSGDEKERAE
                     HVMLVDLARNDLGKVAVSGTVRVSSRMKVERYSRVMHLVSRVEAGLKEGHTAVEAFRAC
                     FPAGTVSGAPKVKALEWIARLEPSPRGWYAGAGVLFGGNGDMDSWILIRTARFAKEKVT
                     VRTGAGIVADSEPEREAEETENKAAALFRAIRLAEMTAVGEGSP"
     misc_feature    21364..21378
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.57"
                     /tool="antismash"
     gene            22849..23877
                     /gene="trpD"
                     /locus_tag="EG886_RS06345"
     CDS             22849..23877
                     /EC_number="2.4.2.18"
                     /GO_function="GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019005461.1"
                     /locus_tag="EG886_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="WP_124727345.1"
                     /transl_table=11
                     /translation="MSDRLLEKVLNGMDLTREEAGRLMERMIDGGLTSAKTASWLTALR
                     MKGESVEELAGFAEVLRQRAVRVHLTDPDAVDTCGTGGDGGRTFNISTAAAIVAASAGV
                     TVAKHGNRAVSGKTGSADVLEALGVEIPQHEKLAERMLRKTGIAFLHAPLYHRALKRVG
                     PIRRELGFRTVFNLLGPLVNPAGVKRQLVGVFHPRLTSVLARVLGELGAHRAMVVSGFD
                     GLDEITVTGPSLVSEWRDGRVYTYEVSPEDVGLSRWRPEEIRADSPRESAHMILKVLGG
                     ESGAPRDAVLLNAGAVLMMADRASTLEEGVRLAADAVDSGRALRRLENWARISREVRHI
                     VS"
     gene            23867..24661
                     /gene="trpC"
                     /locus_tag="EG886_RS06350"
     CDS             23867..24661
                     /EC_number="4.1.1.48"
                     /GO_function="GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018886231.1"
                     /locus_tag="EG886_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="WP_124727346.1"
                     /transl_table=11
                     /translation="MYLERILEGKREEIRRLRQVYRGEYFRKRVISFEPARSLRKAVER
                     HVGMPLIAEIKPASPSKGTIRKDVLPEVRAVQYREGGAAAVSVLTERQFFHGAPEWLMR
                     VRRVVELPVLRKDFILDPVQLVESRWLGADAVLLIASILEPGELRSLVHQARELGLETL
                     VEIHEEGELPAALAAGPDLIGINNRDLSTFETDLSVTERLLPLVPPGIPVIGESGIASP
                     DDVVRLRRAGVSGVLVGECLMRQEDPVTAVRELIGAGVDCAG"
     gene            24658..25314
                     /locus_tag="EG886_RS06355"
     CDS             24658..25314
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012900.4"
                     /locus_tag="EG886_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="WP_164491691.1"
                     /transl_table=11
                     /translation="MKSIHVKLCGFRRPEEVREAAALEVDRIGFILARGRRRSVEPEVF
                     PDLVREAGPDRSVGVLVDPAMEEIGTWLDRATWKTVQLCGGESPDFCRRVKETFGLSVI
                     KVFHVCQCGKQPAFPLDAYASSVDAFLLDAFAPEGGGGGKTFDWNLIPPVLDRCRRLGK
                     PLWVAGGLTASNVGKLLGRIRPDGVDVSGGIERNGKKCPETMKRFLKEVRSHEDT"
     gene            25301..26530
                     /gene="trpB"
                     /locus_tag="EG886_RS06360"
     CDS             25301..26530
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003387071.1"
                     /locus_tag="EG886_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan synthase subunit beta"
                     /protein_id="WP_124727348.1"
                     /sec_met_domain="PALP (E-value: 1.6e-47, bitscore: 159.6,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLDEQMTEAAGKFGRFGGRFVPETLMSPLSEVERAFGDAIRDE
                     EFMQKWSGLLRNFSGRPTPLTYAARLTEHAGGARIFLKREDLNHTGAHKINNALGQALL
                     AKRMGKKKVLAETGAGQHGVASATAAALLGLACDVYMGEEDMCRQELNVFRMQLLGARV
                     IPVTTGSRTLKDATNEALRAWSRQAETAYYLLGSAVGPHPYPRMVKTFQRVIGDEARAQ
                     LLEAEGRLPDHAVACVGGGSNAIGLFAAFLDDRSVSLHGVEAAGEGLHTGRHAAAVCQG
                     RPGILHGMHSLFLQDETGLVKQAHSVSAGLDYPGVGPEHAFLHETGRVRYAAVTDREAL
                     HAVDLLCRLEGILPALESAHAVAEAVKIASRLPKDKVVLVCLSGRGDKDVGTIRDAWGG
                     KAHASFEDVV"
     gene            26505..27302
                     /gene="trpA"
                     /locus_tag="EG886_RS06365"
     CDS             26505..27302
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708545.1"
                     /locus_tag="EG886_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="WP_124727349.1"
                     /transl_table=11
                     /translation="MHRLKTSFEKPGSRVIPFLMAGDPDPGTTLELMRLLAEEGVTAIE
                     LGVPFSDPVADGPVIQAASGRALDRGVRLPDVFRLGRSFRESDPDTPLILFSYANPIYC
                     HGVERAAEESAACGFDGWIIPDVPVEESGPWKKAAESRGLALIPLVAPTSSERIRRIVA
                     EASGFVYCVSSLGTTGVRSRFDDRLERTVAAVKDTVPLPVAVGFGVSGREQSRRIREFA
                     DAVVIGSALVKRIHDARFLLSEGSKRREAMEAIRAFVREVKSE"
ORIGIN
        1 cggtttgtcc accaatttgc tggagcggac ggcggacgtg atgctcaagg aacggcgtcc
       61 tttggtgatc gtgccccggg agacgcccct gtcgcagatt catttggaaa acatgctgaa
      121 actggcacgg tgcggagcca ccatcgttcc ggcgatgccg gctttttatc accggccaag
      181 aagcgtggat gacatggtcc ggtttgtggc cgggaaagtc ctggatctgc tttccgtcga
      241 ccatgcactc taccggcgct gggagggtgg acaatgacag tccgagtcgg aaagatctca
      301 ttcaccaatg tcttgccgat ctatcaacac ctggatgcaa cgggcctcga catcgaactt
      361 gtccccgagg ttccggcgcg tctcaacaag gcgatggcag agggcggcat cgacctcagc
      421 cccatctcat cttttgcgtt cggagcgcgt caccgtgatt tctatctctt gccggatctg
      481 tccgtcagcg catgggggga cgttcgctcc gtgtgcctgt ttaccaaagg aaagagcctg
      541 tcggagttgg acggggcgcg tgtggcgttg acacccaaat cggcctcgtc cgttgccttg
      601 ctcaggattt tgctggaaag gtatgagggg gtcaagcccc gttacgaaac catggagccg
      661 gatttgccga gaatgttgga atccgcggat gcggcccttc tgatcgggga tgatgcaatc
      721 gtcggcggga gagcccaccc cgaatatcgg gtgttcgatc tcggccgcga atggcatgag
      781 cgaaccgggc actcgatgac atttgccgtt tgggccgtac gccgggaagt ggcccatcgg
      841 tccccgaacg agctggcgaa catccatgaa cgctttctgg aagcaaaaga atcggggaaa
      901 cgggatttgc gtccggccgt ccatgaggcc atgcgtcttt tgggaggcga cgaaggctgc
      961 tgggagaggt atttcagggg attgacgtat gatttgggcg aacgggagct cgaagggctc
     1021 aagctctttt ttcgccactg cgcggagctt tcgctccttc cggaagacgt ggagatttgc
     1081 atgccggacc tcggggccgg aacaggcatg cgctgatcag ggtgaagcgg atgaatttgc
     1141 aggacattta tctgaatctg aaaaaagacc tggagattgt cgaacaggca ttggcccgct
     1201 cggtcgaagc ggacgtggcc gtgctgcgtg acgcatccct ccatctcctg aaatccggag
     1261 gaaagagaat gcgtccggtg tttgtcctgc tctccggtca tttcggccga tatgaagtcg
     1321 agcgtctttg ccgggccgcg gttgcattgg agatgattca catggccaca ctggttcatg
     1381 acgacgtgat cgatgacgcg gacacacggc ggggacggaa gacggtaaag gcggaatggg
     1441 acaatcgcgt ggccatgtat gcgggggatt ggctgttcgc aagggctctc cgggaattgg
     1501 ccgatctggg ggatcaccgg gttcaggtca ttctggccga agcgatgcgg ctcatgtgcc
     1561 ttggggagat cgagcagatt gaggatttgt acgccgaacg gctgtccctg aggcgctatc
     1621 ttcgccgcat caagcggaaa acggctcttt tgatgtccat cagctgtcat ctcggagcgc
     1681 tggttgccgg cgcgagcgag gagcacatcc ggttgctgcg tgcgtacggg tattacgtcg
     1741 ggatggcttt ccagctgacg gacgacgtgc tggatctgac gggagatgaa cggattttgg
     1801 gaaaaccggc cggaagcgac ctcaagcagg gcaatgtcac gttgccggtt cttcacgtgc
     1861 tgcacaccgg aacggcggat cacagacaga aaatcctgga cttcctgcgc tcacagggaa
     1921 tggccgacaa tctgggggaa gtccttgaca tcgtgcgggg aggcggcgga gtggaagcca
     1981 ccctcgagct gtcccgccgc tatctgaaca aggccatcga ctgcctgaac cggctccccg
     2041 attcccacca gcgtgaatcg ctccggttga tcgcggagtt catcgttcgc cgaaactatt
     2101 gatcgagttg cgtttgtcgg acttccttgc taaaatttga gtgtcgtcgc ccgaccggtg
     2161 accgacgttc tacataggaa ccgacggagg aatccatcat ggaaaaaacg tttatcatgg
     2221 tcaaacccga cggcgtgcaa cgcggtctga tcggagaagt cgtctcccgc tttgaaaaaa
     2281 agggatggca gcttgtgggc gccaaattca tgacggtttc ccgcgaactg gccgaaaagc
     2341 actacgccga gcacaaggaa aaaccgtttt tcggtgaact ggtggacttc atcacttccg
     2401 gtccggtctt tgccatggtg tggcagggcc acaacgtgat tgccggcgcc cgtcagatga
     2461 tgggcaaaac gaacccggcc gacgccgctc cgggaaccat tcgcggtgac ttcggcgtca
     2521 acgtggcgat gaacatcgtg cacggttccg attccccgga aagcgccgaa cgtgaaattg
     2581 cactctggtt cggcaacgaa gagctggtca attgggaaaa aaccatcaac aagtggatct
     2641 gagcggcacg aaaaacgcac cttccggatg gaggtgcgtt ttttcatggg gcggggaaat
     2701 ccccgacacg tcaggctacg tctctcctgg cgaacaccca ccaggaaatg cccgtgaaca
     2761 acagaaagtg aaccacaagc accgtcaggg aaaaagcgag ggtcattcct tccgcgggag
     2821 gtgaaccttc gccgaaatac gggagaagat cggtattggc aaacaggatc caacggatcc
     2881 agtcggctcc gcggagggac aaaatgttga ccgcctgatg gccggcaaac atcagaaata
     2941 cggacagtcc gatggccgcc gagctgctgc ggaacacggt ggagatcatg aatgcgaacg
     3001 tgaccatcat caacagttcc gccgtgcttc cggcaaacag aatgagaaga tgggccggca
     3061 cacttcgctc gatgatctgt tgtccgtcat gaatcaggcg gggaggtccc caggattcaa
     3121 atccgaacat cactccgccg accaggggca acaggacaaa caaaaggagc agcaatccga
     3181 gggcgaacag cagaatggac aagtatttgg ccagcaggat ctgagatctt cccggaggcc
     3241 ggatcagcag aaacttgatg gttcccatcg agaattcgcc ggcgacggcc gttgccccgg
     3301 tgatcaccgt gaacagggtg accaggggaa tcaacaacgt tccggtttcc cgggtgaatt
     3361 tccacatgag aggttcgtga ggaggaaggt ttttctgaag ccggtattca ttgatctcca
     3421 ttttttttct ggtctcttcc gccatggccg gcggaagttg tcctttggac aggctctccg
     3481 ccagttgttc gttttccagg agcagggatt gcttccaggg atcggcggga gcttccgccg
     3541 gttggtatgc cttcatgacg aatgccatca ggatgcaggc cgcggcaaga atcccgcaca
     3601 tcaccggggt ggagagccgg cgccagattt tcatgttttc gttttgcacc agacgcagaa
     3661 agcggatcat gctcccactc ctcccgtcaa cgacaagtaa cggtcttcca gggagatgtt
     3721 ttccgtccgg atttcgtaca cccggatgcc tgacttgacc aattccgcgt tcgcttccgg
     3781 aatttgttcg tatttcagcg agatccggag ccggtcgtct tcgacgtgta ccgttcgttc
     3841 agggaagagg gttcggagaa tttgttccgc ggagggaagc ggatccgcga aaaaaaagac
     3901 ggtccgttcg tgttcctcat ggtttccgcg ccagtcattc agtctccgct cttcgatcca
     3961 ttccccctgc ttcaaaatgc cgaatcggtc gcacatggct tccatttcag cgaggatgtg
     4021 gctggaaacc aaaatggaca ggttttcttc ccggaccaac cgtcgcaggt catcgcgaag
     4081 attgcggatt ccggccggat ccagtccgtt ggtcggttcg tcaagaatca atattttggg
     4141 cgagtgcagg agggcctgcg cgatgccgag gcgttgtctc attccgagag aataggtttt
     4201 caccttgtcg tcaatgctgt ccccgaggcc gaccatccgg acgacttcac ggattcggtc
     4261 gcgactcacg tgatcagaca tgcgggcata atgaagcaga ttgtgataac cggaaagaaa
     4321 cgggtagaat tcagggtttt ccacaatggc ccccacccgg gaaagggcca gggcgcgatg
     4381 ggttttcagg ttgtggccat cgatgaaaat gtcgccttcc gtgggggaca tcaatccggt
     4441 gatcagccgg atgaccgtgg tttttccggc accgttggga ccgagaaaac cgaaaatttc
     4501 acccggatac aggtcaagat ggagtcggtt gacgatgact ttgtctccga tctttttggt
     4561 cagattccga acggtgagaa caggggttgg cactcacatc cctccgcatc aaggattcga
     4621 cggaaaggga agccggcagg gttgccggct tcccggaagt accttgccat cggcaccggt
     4681 tacaccgatt tcctgcggaa atacgtcaat ccgatgaaaa tcgccaggaa taacacgacg
     4741 gggacgacag tcaggaacat gccggacact cccgtggttc ctccctgcat catgccgatg
     4801 gccgggagcg cccagggata cagggtaacg gaagacgatt tgagctcgga gctgatgatc
     4861 aggaagaccg gcacggtcaa agccacattg ctgatcatcg gtttgacgaa cccttccatc
     4921 cacaaggcca gggaatattg aatggcggcc agcggcaatg cgccgaccca tccggacatg
     4981 gcgctgatga aaagggtgcc ccaaggaacg gggccgtcaa gtcccagaat ttttcccaca
     5041 gcgacaaaca gggcgagagc gaagatctgc gcgaagagaa gcagggcgta aagccagatc
     5101 agttttccga aaaaaagctg atgccgggga accggaaacg tgaacaactg tttccacccg
     5161 ttgcccgtct gttcgaaacg gcagaggctc gtggccacca tggcggacag aatgggatag
     5221 aagatcccgc cataaaacat gatggacatg gcccagggca tgaaccagag gttgtcggct
     5281 tcgaaccggt atttgccgat catgataccg acgtagatga acagggtgta caggatcggc
     5341 aaggacggca agatcaccag aagcagccag attttcgaac ggcgcagttt gatccactcg
     5401 gcttgaagga ttccggtcac ggaagttcct ccccatcttt cggatgatct cgtaggattc
     5461 ggttcaccgg gacatccacc ggaaaaaatg ggcgccgccg gccatgagga gaaccagcgt
     5521 caggacggca ccggtcaacc agacgcgcga atcctgaaac gggagaccgt atccaggcat
     5581 gaacgtggtc aagtaacccc aaggtgtcca ccagcccgcc tctttgaaca ggggccccaa
     5641 tatcatgccc gccgctccgg ctccggtgga aacaccctga tgctcgaaaa cttgagacaa
     5701 ccaggtgtga aaagcgatca acggcgtcgt gagcaagaac ggcacccagc cgtggaggaa
     5761 cagggagcga agggaaactt cattgcccaa attccacatg atcacggacc cggccaacaa
     5821 cagggtcatc aacaaaccgg acaactggat gaacaggaaa ttccacagga actttcccgc
     5881 gtacagttgc catttcggga ccggcatggc cagcaattgt ttccacatgc ccgtttgatg
     5941 ctcgatttgg gcggtttgtg cggtgaacag aggaacgccc ataaacagga cggggccgag
     6001 aaacaaggaa agagtttcca tggcgatggc ccacactttt tcagggggtc ttccggtttc
     6061 gaacatgtac cagatcatca ccgtcaaaaa tccccacaat ccggccggaa tcagacaggt
     6121 cagcagccag acggaagtgc gcctgttctt gatccattcc gtggaaagca cgttcatcat
     6181 gacggggaat caccggcctc cacaagattc agaaagatgt tttccaaggg ggggcgttcc
     6241 tcttccaagc gccgaatgat gaagccgtcc tgcaccagaa gtcgttggat ttcccggagg
     6301 gtgttttccg cttccgatgt cggaagaacg agcagccctt cttccaagtg gacggagaat
     6361 ccgtgttcct ttaacaattt ggccgcatct tccgggcggt cgacttcaat caccgttcgg
     6421 gaacgggtgt gttttcgcag cgattccagc gaaccttgaa acagcaattt ccctttgtga
     6481 atgattccca cgtcatccgc gatctgttcc acttcactca gcagatgact ggacaacagg
     6541 atcgtcactc cccgctcgcg gggcaagcgc ttgatgaggt cccgcatctc ccggatgccg
     6601 gccgggtcca gtccgttggt gggctcatcc aggatgagaa ggtccggatt gttcagcagg
     6661 gcggtggcaa gccccaggcg ttgcttcatt ccgagtgaat actgtttcac tttcttgttg
     6721 cgggcatctt ccagtcccac caggctcagt gcttcgtcga tgcggttttt gtcggggatc
     6781 ctgtacagtt tccgggccac ttccaggttt tcgtatcccg tgagctggcc gtaatagctc
     6841 ggggtttcca ccagagaacc gacccgtttc aaaatcgaaa ggcggttgtt tgagaattcc
     6901 tgtccgaaca tgtgcacggt gcctccggtc ggtcgaacca atccgagcaa catgcggatg
     6961 gtggtggtct ttccggcccc gttcggtccg agaaaaccgt aaatggttcc gcgtctgact
     7021 tcgaggttca ggccgtcgac gacccgttgg cggttgtaca ctttcgtgag ttcgtccgtt
     7081 ttgatcaatg cctcttccac aaagatccct ccagtcgaag ctcagtaacg cttgcgaagg
     7141 accagcagac gaacggtacc gacgacgtag gtgaggcaga gcgacaattc gatgattcgc
     7201 cggtaaagtt catacggaaa gtcaaaccgg gcagccagaa acaccagcca cgcgatgcag
     7261 acggacaaca ggaaaaacat gaatcggaaa aacttgttga aaatcagttc cccacgctcg
     7321 tcttttcctt ctttttgata gaaataagca atcaccacga gcgagaaaat catccatacg
     7381 gagctgaccg ccgtcaacga tttcaaaaga acggctccgc tcattgtgaa tcttcccctt
     7441 cttcctcata ttgaaaaatg tcttccacgt tttttccgaa caggcgggcg atccggaaag
     7501 caagcagaac ggacggaacg aatttgttgt tttccaccga atgcacggtt tggcgactga
     7561 tgccgagccg gttggccact tcctgttggg tccaaccctt ttccgcacgc agtacggtca
     7621 agcggtttcg cagaatcccc ttgtttttca cccccgcttc ccctccttga gccgtggtct
     7681 ttgaaattgt accatttttt tgacagcatg taaagtatac tttacatacg ggcgaaaaaa
     7741 gattcccgtt caaaaccgat gaacgggggg atctcacgtg aagatcaggg atgcgttccc
     7801 acggcggcat ccgcttccgg attgcggacc gatgacccgg ttacttccgg tttcttcaga
     7861 tccttttcat agaaacgacg gtagaagccg ttttttctca tcagttcatc gtgagtgccc
     7921 tgttccgtga tgcggccgtc ttccagcacg agaatcaggt ctgcgttccg gatggttgtc
     7981 aaccggtgcg tgatcacgat tcgggtgcat ttcatgtcgg acagcacccg gtcgatcttc
     8041 tcctcgttca cgtgatccaa ggagctggtg gcctcatcga gcagcagaac ggaaggtttg
     8101 tgaaccaggg ctctcgccaa cgtgatccgt tgccgctggc ctccggaaat gttcattccc
     8161 agttcggaga tcatggtgtg gtaattcatc ggcatttcca tgatctcatc atggatttgg
     8221 gcgattttgg ccgcttccgt cacttcttcc atggaggcgt cgggtttgag cagggtgagg
     8281 ttttcgagaa tggtccggtt gaacagcatg tcatcctgag gaacggcgcc gatgtgtttt
     8341 cgcagtgctt gtttgtccag agtcttcaga tcgtgaccgt caaacagaat gcggccttcc
     8401 gtgggaacat acagccccag gatgagtcgg gccaacgtgc tcttgcccga acccgacttg
     8461 ccgacgagag ccactttttg tcccgggagg atcttcaggg aaacgttttt cacggcgggc
     8521 gggctgaatt tggtgtatgc gaaactgaca ttctgcagtt cgatttctcc gcgcaaggaa
     8581 gagaggcgaa tcgggttttc gcagacaggt tcttccttcg cgtcgagcac gtcctggatc
     8641 ctgcgcagga atgattccgt cagaaagaat gaattcaccg tgttcacgat ggaggagctg
     8701 agtccgaaga attggttgga gatcgagtag aaggcgatca tgccccccag cgtgagctgt
     8761 tcgctcacga tcatgtgcac gccgatccac aggacggaca gcggagccag caaggacagg
     8821 aaacccgtgg ccgtgttgac atggttcaac agattttcct tggcccggta agcgccgagc
     8881 agatcccgga agcgttcata ccactggttg tacatcatcc gttcgatgcc cgatgttttc
     8941 acgccgaaga tcccgtacag catttccgcc tgggatccct gcaccagcgc ctgcctgttg
     9001 atttcttcct ggttggcttc ggtgatccgg ctccggtacc agccgagaac gaatacgttg
     9061 agtccggcca tcgccgccac ccaaccggcc atcagggggg acacgagcgt catgtaaagc
     9121 agcatcacga tcaagattcc aagatccagg atccccttga tcaactggtt ggacaaaatg
     9181 tcccggatga cccggtgact gttggcccgg aaatggagat caccgaatga gtggagttgg
     9241 aaaaattggt aaggcaatcg aagcagatgt gtaaaaaacc gggtcatcat cccgtgatcc
     9301 agccgattgt gcaggatgat caggcatttt ccgcggatga aggtgaaaac ggtctggaac
     9361 aggaccagca ttccgatccc gaccagaaac atgttcagca ggtcgtactg cttcggcgtg
     9421 atgatttgat ccaccacaaa ctggatcagc atcgggattc cgaccgcgaa cagctggagc
     9481 aaaagcgaga tcgccaggat ggacacgaag agcccgggat gttcccgcag ggaagccaga
     9541 aacggcttcc acacgctttg tcctttttgc cggacgaagt gttcccccgg gcacagttgc
     9601 atcacgacgc ccgaatagga tcgcatgaat gcctccgggc tgagacgtcg gcgtccgatc
     9661 gccgggtcga caatgacgaa atgctttttc gtgacggatt ccagcacgac ataatgtttg
     9721 tcgttccaga acaggacggc gggcagcggg agctgcctca gtgaggaggc atccagtctg
     9781 taacatttgg tttcgaaccc cagctgttcc gcgagattgc gaagatgaaa aagggtggtc
     9841 ccgtcccgac cgccgcccat ccgttcccgc aattcgtaca gggagaccga gcttttgtaa
     9901 taggcggcga tcatggcaat gcagcacagg ccgcactccg tctgctgcat ctgctcgatg
     9961 aaagggacgc ggcgacgcgt gaacaggcgt tttcggcggt tcacccgatc atctctcctt
    10021 ccggaagctc cagggccaac acggacggga tcgacggatt cacgagacgg agcaggccgt
    10081 agccgattcc ggaaagtccc agcatcagac cgaggagttc ggcttccggg tttttgtgat
    10141 atccgaactt ccaaccgtcg tccaatcctc gccgcaaact gcgcgttccg atttccgcgc
    10201 aggtaacccg gaggtgttca tgccccggaa tgccggctga gagcaacaga aaatcgagat
    10261 ttccgaaatc accgtggcac agggaatgat tgccgccgaa gccgctttcc agcgttttct
    10321 ccaccgcgat gctccattct tccttcagca ggggatcccc ggaaacattc gccattttga
    10381 gccggctgat gccgattccg ggagccccgt ggcaccagta cacgggatga ttgcggacgt
    10441 ctcccgtttc gcgcagatcc atccaatttt tttcccgggc gatgaagtgt ttccgttcgt
    10501 atgcaagggc tcgttcggcc gcgagcgcaa accggctctc gccggtgacg gccgccagtt
    10561 ccgtccatgc ccatgcatat cctgccgctc cgtgtgacag tccggtcagc catccgccgg
    10621 aatcatcttc cccgatccgg acatggcgca acagatgaac cccgcatttg acggccatat
    10681 ccaaagcgga agaggacggg cggattttgt gaagacgaag acagaccagc aaggctccag
    10741 ccgccccgcc gatcaggtca aagtgccggt cggcttcgag agcgttcgga atggagggaa
    10801 gccggtcaaa cgctttttcg agcagctcct gatccttcca gagcaaaccg aggtacgaca
    10861 gcccgtacgc cagcgaggtc agtccgctga acgcggaaac cggcaggggt ttgccccgga
    10921 gcagggtgaa cgttcccgag agcgcggctt tggcgagacg tgtccaggtt tcatcgccgg
    10981 tttcttgtcc caactgggca aggaagagga tgattcccat ggttccgtcg taaagaccgc
    11041 tttccaacgc ggcaatctga aggctttctt cgcccggagt caaccccagc caatacgctt
    11101 ctttccggtc gtcgctccag atggcccgct gaagaagttc atgaccgatt tctttggccg
    11161 cctcgaggag ttgttcccgt gaagccggtc gaatcggtgc cttttgttcg gaggaggaat
    11221 cgtttccggt ttccgtgact tgggcatcat ggacgagcgt ggccatcgac atccggatgt
    11281 agccgcactg tttctcgcag tcggcggggt ccagttcccg gcatcgttcc agtacctgat
    11341 ctaggcaagt ccgttcaaaa aagtcccgaa tttcccggcc ccggctgtca aacaagctgc
    11401 ggccgttcat ccggaaagag aaataaggaa tgtcatgctg caacagatca tccgtttcca
    11461 tggggatcat ttgtccgtac cgcgggatga cggaaacggt tcgccagaaa aattcgaaca
    11521 gccggttacg gtccagaccg tcctgcagat aatcgggatg gacgcttgcg tcgagaaagc
    11581 ggctgtatgt ctgggtgggc cggaaaatgt ggcgcacctg atccccggca aaacggtgga
    11641 tcggccccgt ttcggacaga agttcgtccc ggtgggtgag gaacagagag tacatttcgc
    11701 ggaatccttc ttcgatttcg cgactgtatt ccgcgggatc cagttcctcg ccgccgagcg
    11761 tgggacggtt gcggtgtccg ggggaacgcg ccggcacttc caccaatctc atttcatccg
    11821 tccccggttt gtgcaccgtg cggatcttca gggttttcga ttcttgccct tgttttcccc
    11881 cgatggcgct gagatccaga tccagatacg gattgttggc caacttcagg gggatcaaca
    11941 tggagccgaa cacggaattg ttcagttcgt caagcacttt cggaatggag atccgactgg
    12001 acaggatttc gaaccgttga ctgaacagcg tttcgagatc gatcagcacg ggatgctctc
    12061 catgggcaat gacattttcc gcatggaaat cggaagatcg aagcaagtac aggagagcgg
    12121 catacccgcc ctggcggtaa tagaaattcc gggcttcctc cttgctccgg caatcggtgt
    12181 gttccacgta ctcttgccag ccgtgggtcc ctttgtccag cgctttggcc gggaggagcg
    12241 gacgggaaaa cccttttccg ttgatccagg acagaagctc cccgtagtgg acgtccaccg
    12301 ccattgaccg gggtttgtat acgagttttt cgcccgattc aaattggaaa atcgagacgc
    12361 ttcgtccgtt ttgatgagtg tctccggctc cggaacggat cccgaccagt ttggaaaaac
    12421 gtccgttgaa cgtgcgcaaa atgtcatctc tgtctttcaa aaagcgccga agggattctt
    12481 cgtgcgtctc aatcgcttgg gtgaccgttt gggtcaacag acgggcgagc acgggatacg
    12541 tttccagaac ccggtttcgg aacgagggcg taccgagacg gttggcaaaa tcaagatacc
    12601 gttgttccgg agtgtcgccg gaaagctgcc ccgttgcctt catgacatgc agttcggtga
    12661 tcagggtttt gattcccagt gcggacaatc tccggcacac ggtttccagc atcgattcca
    12721 gcagggcatc ggggtcgaac caattccggc attcacatga atgttccagt tcttgaagca
    12781 gccggttgag cgattgtcgt acatggtgca caaagggatg gtagaaggga gaaaaaggaa
    12841 tctgattctc catgtcccgg gcggggacct gttcgttttc gcgcaggatt tccgtcaaac
    12901 gggaaatcca ggccggatcg ttccggattt cggggaagtc gggatcgccg agaatgtcac
    12961 ggaactcccc gagagtcagt ccgtcccgtt ccagtctttc ccgcaacgta ttctccgtga
    13021 aatcaccgga gcgcaaccag ttccggaagc gttcttcccc ccgtgcagga tctgcgtgca
    13081 tgggctgttt ccgttccgaa agaaacgttc ctctgagcca tgccggttgt tcgactgaag
    13141 ccttcatgga ttcaactccc cgtcacgata ttcagcaaaa agacccgctc tccgatctcc
    13201 gcgcaaggga tcgacacttc atggatcaga gagcaggcct tgaatgttca atgttcaaag
    13261 caagacatca gatcagcggc aatcgctggt gcaggcggtc gtcgggcaga aagccaggga
    13321 gaccgggaca cacacggcaa gggtgacggc acagaccgga ccggattgcg ggcgaacttc
    13381 accggcaccc acaatattca tcagttcatc ctcattgacc atgccggcgg gatgttcaaa
    13441 cccttcaaaa cgaagtttcg gatcacgcag ggcgcgttct tgcatcgaca ttccaatccc
    13501 tcccgaatgt tgttgtggag tgcttcgccg aagcaacttc aatataaaag aattttttat
    13561 ggaactgtta tacacaaaat tgcatttttc tttctataca caaaagtgca aatatacacg
    13621 aaactccttg aaataatttt ttgatatata gtaatcttta tttgcgccaa agcaatcttg
    13681 caataaagga gtgtttgtca tgagccgtga gatccgcatg tggaaagatc ccgtcttccg
    13741 gctgcaatcg gaaggaagca tgatggagca cccctccggc aacgtgatgg aagaactgcg
    13801 tgaacaggac cttctctccg tggcgggagg atgtgactgg tggaacatca gctgtcactt
    13861 gggcaacacc ggtcggttct gcacgctgac gaaagagtgc cagcccaact gcaattattg
    13921 atgaaacggg gtgaacggat gaatcaattg gttcgctcct ggaaagatcc ccttttccgg
    13981 gtgcagacag agcaaaaccg gatggagcat ccttccggca acgtcttgga agaactgcgt
    14041 gaacaggacc ttctctccgt ggcgggggga tgtgactggt ggaacatcag ctgccatttg
    14101 ggcaacaccg gtcagttctg cacgctcacg aaagaatgtc aaccgagttg caaccgctga
    14161 cgggaagttc gtgatcttcg gggaaagtgg caatgattgc tgctttcccc tttttcggag
    14221 gagagagaaa aatggatgca acccgatgga tccgggcttt ttacatggat gaacgcatcg
    14281 cctcccggcc ggttgatccc gatgcgttca gtcaacgcat gaaatactgg gaaatgttga
    14341 cgggcggaag ccgtgagaaa ttggaaacct gcattcaggg agtgtcgggt ttcccggtgg
    14401 atcgccttgc cgggctggcc ggggcggagg cgatcaggca ggaagccgtg gctgaagaca
    14461 cctggtttcc cggatttcaa aagtggttgt ccggagcgta tgaccgggtg gtgctcccgc
    14521 cggaaacggg gacggacatc ccttttttcg ggttttttga accgtttctc aagctggggc
    14581 tgggagcgct tcacgaacga ttcccccatg caaatcggct ctcgcaaccg gtggtccggt
    14641 ctttgcttgg acaactggcc caccggcttt tcgaggtcgc gcacgcaacc ctgattctgg
    14701 agctcaatgt ggcccgggtt tccgaaaagt tgtccggtga cacgccggaa gagcggtaca
    14761 ggcacttttc ggaagtcctt ctgagggacg aacagacacg cctttccctg tacaacgagt
    14821 atcccgtcct ggtccgtctt gcggtgacca aaaccctgca ctgggtttct catgtgtcgg
    14881 aattgctgga acggatcgaa gcggatcggg atcttttgag tcaacgtttt cattccggtc
    14941 atgacatcgg tgtgccggag gaaatcgatc tggggctggg agacagtcac aacaagggca
    15001 gaggggtggc gatggttcga ttttccggcg gtcttcgggt gatctacaag ccgagaccga
    15061 tgggggtcga catcggattt caggatttgc tccgatggct gaaccgggag atggccggag
    15121 aggaaccgtt ccgcatattg aacgtggtgg atcggaagac ctacgggtgg tcggaattcg
    15181 tggagaaact cgattgccgg acggaagagg aattggtccg gttttaccgg agaatgggaa
    15241 ggctgctggc cttgttgtat ttgcttcagg cggtcgattt tcaccatgag aacctgattg
    15301 cccacggtga acatcctgta ttggtggatc tcgagtccct gttccaccag accctcgggc
    15361 gaaaggaata taccggcaac gcgacggacc gtgccgagga aatcctgcaa cgttccgtcc
    15421 gctcaaccgg tctgttgccg gctccgctgt attatcgcgg caatcccgga gcgggtggag
    15481 tggatgtcag cggaatcggt gccggcggcg aacagacggc cccgttcaag cttccgtaca
    15541 tcgaaaacaa aaacacggac cggatgcgca tggtcaacga ttacggcaag atcagcgccg
    15601 cgaacaaccg gccgactctc cgcgggtcgg aagtgaagct gtccgtatat ttgccggtac
    15661 ttgagcaggg ctttgaagag atgtaccggt gggtgatgga gcacggggaa tcgttcaagg
    15721 aacggctgta ccggttttcg gacgtacagg ttcgttccat cctcagatcc accatgcaat
    15781 acggaaacct gttgcgccag agtgttcatc ccgacttttt gagggacggg atcgacaggg
    15841 atgttttgct gcacaggctg tggctggaca cggacaccat gccctcgttg aaagcggtgg
    15901 ttcggagcga gaagagagat ttgacggaag gagacattcc gttttttcat acccgtccgg
    15961 gagaacgtca cgtgcgggac agcgaaggcc gtcgtctgga ttgcgagttt cccgtgtccg
    16021 cgctggaaga tgtgtttcaa aagatcgatg cactcagtcc ggaagattgc cggaaccagt
    16081 tgcaggtcgt caggatgtcg attttggccg gcgaagcaag gcatgatgcc gatgtggcag
    16141 cggtggatcc gcgcatgaag gtgccgggcc cgctcccgga gaaggacgaa tttttgcggg
    16201 aagccgaaaa aatcggagat tatctgttgt cgaaggcgat ttccggcttt gatgaagaga
    16261 caggggaaga ggacgcaacc tggatcagca ccacgctgga gggaaccgga gagattttgt
    16321 ggcaaatatc gcccgtcggc aacgatttgt acaacggcaa ttcgggaatc gctctttttc
    16381 tggccttcct ctccgagctc accggccgga gcgatttccg ggaggcggcc gccaaggcgt
    16441 tggttccggt ccggaaagcc gtcaggaaat tcggcgaaca tcccggttgg agcatcggtc
    16501 cgttcaacgg tgcggggggt tatttgcatg cgatgaatct gctggccgcc ctgtggaagg
    16561 atgaagcttt gcggaatgaa gtggaacgcg gattggatgg cttcctgaag atgattccgc
    16621 aagaccggct gtatgatttc atcggaggtt cagcgggggc attgttcgtg cttctgggaa
    16681 tccaccgtcg gacgggaaac cggttggcat tggaaggtgc cgggttgtgt gcggaacatt
    16741 tgctgaaaca tgccgaacgg gcggaaaccg ggatcggatg gagattgccg tgggagaaag
    16801 cgccttacac cggatttgcc cacggtgtgt ccggagtggc ttgcgcactt ttcgaatggt
    16861 atcggttgtc cggggatgac cggttcaaag aggccgtgtc ccaagcactg gaatatgaaa
    16921 gaagtttctt tgatgaggcg gcgggaaact ggaaaacgcc cggaagagat acgccttcgg
    16981 tggcctggtg tcacggggcg ccggggattt tgctgggcag attgatgctg aaacgctcgg
    17041 gattcgaaga tgagaggctg gaagaggaat tggggattgc actggaaacc actttgaaca
    17101 ggggattcgg aaacaaccga tccctgtgcc acggggattt cgggcaaatc ggcatactcc
    17161 ggtttgcatc cgaggtgctc ggagacggac gcttgtcgca atgggccgac tccgctgcgg
    17221 cgcaagtcct gaacgtgatt cgggaacaag ggttccggtg cggtgtgtcc cgcggagtgg
    17281 aagcggcggg actgatggtg ggattggcgg gaatcggtta cggccttatg atgcagtcgg
    17341 ctccgtcgcg gattcccttc atcttgagac tggagtcttg aatgcgcttc gaaaaatgaa
    17401 tccggcggca cgacgccgcc ggattcgagc tctttgatcg caggtttgtt tccgttttat
    17461 gcgtcttttc cgaccctggg atgacgaaag ttggttccgg aagctccatg tttgtttttt
    17521 gcccattggg aggagatcac tctcgctttt tccgagcagt cataccagcc caagtggcag
    17581 accatgatcc caatggatac tctggactga acggaccatt ttttcttgat tgactggatt
    17641 cgcttgcata ccagccgctt gctgatatac agacgtgcac cgatttcctt gtcccgaaga
    17701 ccactggcga tcaggatggc aacttgcttt tcttccggag tcaacgcttt cagttccatg
    17761 atcggagcaa cttttcggtt tccccccttg gaatggttgc tgctgccgga tccgtgcagc
    17821 agaatacgaa gaatgtgagg acttgatgag ggtcttgcag aaccgtccat ttcttcttcc
    17881 gggtttccaa aatttgtcat gaacggatgc atgaccgaat caccaagaac cttatataaa
    17941 tatatcttaa tatatctctg cggataaata aattcaaata ttcggagttt gcaattttgc
    18001 gaagtcacat gcttttgatc aatgagatat aatgggtttt gtcgtggttc gtgaattttt
    18061 catgacgtgg aggattcaaa gtgaagttga cagccaggga acgggaagtg gctctgctgg
    18121 tggcgtgcgg gtatacggac acggaaattg ccgaagaatt gggtgtcagt cgcagaagaa
    18181 tttgcgaaat cgtgtcttcc atcaaattca agtggaaaac caggtcaaga gtggagatcg
    18241 gcatcatcgt ttactatctc ggttggatca aggaagagtt atccggaaag gatttgctga
    18301 gcgcccttcg ctgaacatcg tggtcttcgg ggatcgccgc acgggatgaa accgctttcc
    18361 cggcgcggat ggcatcaatc ggatgttgtg tgaacggaga caagaacaaa gagagatcga
    18421 agagaaaaga tgatgtgaaa agagaatgac gtcgcaggga aacttccggc atcgtgccgg
    18481 attttttatt ttgcgataaa tgtaaacaag tttgcttcgc aaaccaaatc cgttccccga
    18541 agacctttcg accaaaggga ggcaagctga tataatgttg cattgattca aggttctcag
    18601 gagagcagag gaaagaaggg attggaagag atgagatata tgaccgcggg cgagtcacac
    18661 ggtccgcagc tgacagtgat catcgaagga ttgccggccg gcctggtgtt tgaaaaggag
    18721 aagattgatc atcagctcgt gcggcggcag aaaggatacg gtcgggggcg ccggatgcag
    18781 attgaacggg acggggtgca gattttgtcc ggtgtccggt tcggccggac gaccggtgca
    18841 ccggtgacac tggtgatcga gaaccgggat ttcagtcatt ggaaaaaggt gatgagtgtc
    18901 aacccgattc cggaagaagc ggaaaagcgg cggatttccc ggccgcgacc gggtcatgcc
    18961 gatttgaacg gtgcgatcaa gtacgggcat cgtgacatgc gggatgtgct ggaacgatcc
    19021 agcgcacggg agacggcggc ccgggtggcg gcaggtgcgg tggcccggct gatcctggag
    19081 gagtgcggaa tcggattggc gggacacgtc gtgcgcatcg gagagatcgg ggccaagccg
    19141 gtgcaggggt tgacgctgga tcagattcgc gagcgatcgg aagcatcacc ggttcgctgt
    19201 ctggacccgg aagcggagcg gctgatgatg gagcgcatcg accgggccaa ggtggaaggg
    19261 gattcgctcg gtggcatcgt ggagacgatc gtggaagggg tgccggtggg attgggcagt
    19321 cacgttcact gggatcggaa gctggatgca cgaatcgccc gcgcggtggt cagcatcaac
    19381 gcgttcaagg gggtggaatt cggcatggga tttgagatgg cttcccgtcc cggctccgag
    19441 gtgcacgatg aaatcatctg gtccccggaa accgggtatt cccgccggac caaccgaatg
    19501 ggtggattcg agggcggaat gaccaccggc atgccgatcg tcgtgcgcgg agtgatgaag
    19561 ccgattccca ccctgtacaa accgctgatg agcgtggaca tcgacacccg ccggccgttt
    19621 gcggccagca tcgaacgatc cgacagttgt gcggtgccgg cagcctccgt ggtgatggag
    19681 catgtggtgg catgggaagt ggccgtcgcg ctcatggaga aatttcccgc agacacgatg
    19741 gaagagctga cggatcacgt tcgccggtat cgcgagcggg tcagggagtt ttgaaccatg
    19801 aagacgttga cgattgccac gacgtcccgc acctatcccc tgacggtcgg aagcggggtg
    19861 ttgcaaaggc tcccggagtt gttggagcag gtcggcgtgg gaacggaacg tcggttgatg
    19921 gtggtgacgg atgaacgggt ggggccgttg tatgccgagc ccgtgttgaa acgattgatc
    19981 cgttccggtt accgtgcggg cctgtcggtc attccgtccg gagaggcaag caaacgactg
    20041 gccgtgctgg aatcggtcat cggggagtgc ctgcggttcg gtctggaccg gcgcggtgtc
    20101 attctcgctc ttggaggagg agtggtgggg gatttggccg gttttgccgc ggcggtgtac
    20161 atgcggggca tcgatttcgt gcagctcccc accacgcttc tcgcccatga cagcagcgtg
    20221 ggcggaaaaa cgggcgtcaa ccatccgatg ggcaaaaacc tgatcggcgc gtttcatcag
    20281 ccgctggccg tggtgtatga cgtggacact ttgcggacgc ttccaaagcg ggaagttcgt
    20341 tccgggctgg ccgaagtgat caagcatgga ctgattcggg atcaggcgtt tgtcacctgg
    20401 ctggagtcat tcagggaacc gcttcttcga ctggaaccgg acgcggtgac ggaagccgtc
    20461 tggcaggggt gccggatcaa ggcggacgtg gttgccgccg atgaacggga atcgggtctt
    20521 cgagccatcc tcaattacgg gcacacgatc ggtcatgcct tggaagcggt gacgcattac
    20581 ggggcgtaca cccatgggga ggccgttgcc atcggcatgg cgggggcggc gagactcggc
    20641 ggaaaggtgc tgggaacccg tgatgacgtg gttcgccgga cggaagagct gcttctctcg
    20701 tacggcttgc ctgttcgcca tcgatggagc ggaccggaca cggaactgct ttcggtgatg
    20761 aagcgggaca agaaatcgct ggacggcggt ttcgcctttg tgctcacccg ggaaatcggg
    20821 agggcggagc tgattcggga cgtcccggaa gatgcggttc gcgaagtgct gacgcaactc
    20881 cgggaaggga cttgaagaca atcgcagtgt caacaatccc ggaggatgca tctgcctgac
    20941 gggatgcggc gaaaacaccg cattgtcgga gacatcggcg gcgtgatgtg ggattgacac
    21001 gaaccgtctg gaggcataga ctgaaagtgt ggctgatgga gttcgtgatc cgttcagcca
    21061 agcggagtga gacgtcggct tgcacgggct tgccggcgga gtgagcggag tgtgcacgaa
    21121 gtttcgtgcg cgatcagagt gagtgaaaga tcttttttcc gaccaactga atgttgagcc
    21181 gagatgagtg gagcggagaa tggaacgcgg agccgagcgg agaagagccg agatgcatgg
    21241 accacatcgg ccggagcggg cattcgcttc ggtcgttttt gctttttctc cccgttttat
    21301 ttccccttcc gttctcctcc tttccacgaa aggagggacc ttcttgagag ccgttttgtc
    21361 gccggaagaa gtgttccggc tttcccgccg gttttcatgc attcccgtca tgattgaaac
    21421 ggatgccgcc gaggaaacgc cgattcggct gtatgcccgg atgagccgaa agcacggatc
    21481 gtttctgttg atcaagcagc ggtttgcctg gatcgcggac gatcccgtcc ggtgtatgcg
    21541 cagccatcgg gggagctggt ttctccgcga tgggcaaggg cggatcctcc cggtgacgga
    21601 cccggatccg tttgtttggt tgaaaaaaga gttggagcga aaccggtttc cccgattgtc
    21661 cggatgcccg ccgctggcgg gggggatggc cggctggatc ggcttcggat cggttcggtt
    21721 tttggagccg aaccgtccgg taacccgtca tccgaacgag gatccggaca tctgcctgat
    21781 gcggtttgat cgaatgtcgg tcatggacca aaaacgcggc aagttgtggt tcacggaagt
    21841 gctgaagatt ccggacggaa tcggaaaatc ggaaatgttc gccctgtacg ggcaggccgt
    21901 tcagaggttg atgacctggg ccggggagtt gctttcccgt ccggtgaggt tgtccgagcc
    21961 ggcgtttgac atggaatttc ccgtgcggga aacggatgtt tgcggatgga ccgaagagac
    22021 cgacccacac gccttccatg agtcggtaag gcaggtgaag gaacggatcg cgtccggcga
    22081 cgtgtttcag gtggtgcttt cccgaagctg gtcacgcccg cggatggcgg accctttgga
    22141 tgtgttgaga gtgttggaga ggatcaatcc gtcgccttac ctgtttttga tggaaacgga
    22201 agaagagtca ttggtgggcg cttctccgga aacgctggtc cgtgtcacgg acggccgggc
    22261 ggaggtgcat cccatcgccg gaacccgccc ccggggatcg acacctgcgg aggatgaacg
    22321 tctcgccgcg gaattgtcgg gcgacgaaaa ggaacgcgcc gaacatgtga tgctggtgga
    22381 tttggcgcgg aacgatctcg gcaaggtggc ggtgtccggc acggtgcggg tgtcctcccg
    22441 gatgaaggtg gaacggtatt cccgtgtgat gcatctcgtg tcccgggttg aggccggtct
    22501 gaaagagggg catacggcag tcgaggcgtt ccgtgcgtgt tttcccgccg gaaccgtgtc
    22561 cggagctccg aaggtgaagg cgttggaatg gatcgcccgg ctggagccgt cgccgcgcgg
    22621 ttggtacgcc ggtgccggcg tgctgttcgg cggaaacggg gatatggatt cctggatttt
    22681 gatccgaacg gcacggtttg caaaagagaa ggtgacggtc cggacgggag cgggcatcgt
    22741 ggccgattcc gaaccggaac gggaagcgga agagacggaa aacaaggcag ccgcattgtt
    22801 tcgggcaatc cgtctggccg agatgactgc ggtgggggag ggaagcccat gagtgaccgt
    22861 ttgcttgaga aggtgctgaa cgggatggat ttgacccggg aggaagccgg gaggctgatg
    22921 gagaggatga tcgacggagg gttgacttcc gccaaaacgg cctcctggtt gaccgccttg
    22981 cggatgaaag gggaatcggt cgaagaactc gccggtttcg ccgaagtgct tcgtcaacgg
    23041 gccgtacgcg tgcatttgac ggatccggat gcggtggata cctgcggcac gggaggtgac
    23101 ggtgggcgaa cgttcaacat ttccacggca gccgccatcg ttgccgcctc ggcgggagtg
    23161 acggtcgcca aacacggaaa ccgggccgta tcggggaaaa cggggagtgc ggatgtgttg
    23221 gaagccttgg gcgtggagat tcctcaacac gaaaagctgg cggaacggat gctccggaag
    23281 acgggcatcg cgttcctgca tgccccgctt taccaccggg cgctgaaacg agtggggccg
    23341 atccggcgcg aactgggttt ccgcaccgtg ttcaacctgt tggggccgtt ggtcaatccg
    23401 gcgggggtca aacggcaatt ggtgggggtg ttccatcccc ggctgacttc cgtgctggcc
    23461 cgggtgctcg gagaactggg ggctcatcgg gcgatggtgg tgagcggatt cgacgggctg
    23521 gacgagatca ccgtcacggg cccgagcctt gtcagcgagt ggagggacgg acgggtgtac
    23581 acctatgagg tgtctccgga ggatgtcggt ctttcccgtt ggcggcccga agagattcgt
    23641 gccgacagtc cccgggagag tgcgcacatg atcttgaagg tgttgggcgg tgaatccggt
    23701 gcaccgagag atgccgtgct tctgaacgcc ggtgccgtgc tgatgatggc ggacagggca
    23761 tccacgctgg aagaaggggt ccggttggcc gcggatgccg tcgattcggg acgggcgctg
    23821 cgacggctgg aaaactgggc gaggatttcc cgggaggtgc ggcacattgt atcttgagcg
    23881 aatattggaa ggaaagcggg aagaaatcag gcggcttcgt caggtgtacc gcggtgaata
    23941 tttcagaaag cgggtgattt cgtttgaacc tgcccgatcg ttgcgaaaag cggtggagcg
    24001 gcatgtcggg atgcccctca tcgcggagat caagcctgca tctccttcga agggaacgat
    24061 ccgcaaagac gtcctccccg aagttcgggc cgtacagtac cgggaaggcg gagccgccgc
    24121 cgtctccgtg ctgacagaac gtcaattctt ccacggggca ccggaatggc tgatgcgcgt
    24181 caggcgggtg gtggaacttc ccgttttgcg caaggatttc attctcgatc cggtgcaact
    24241 ggtggaaagc cgttggctgg gagccgatgc ggtgctgctg atcgcatcca tcctggaacc
    24301 cggggaactt cgcagcctgg tgcatcaagc ccgcgaactc ggactggaaa cgttggtgga
    24361 aattcatgaa gagggggagt tgcccgccgc gctggccgcc gggccggacc tgatcggcat
    24421 caacaaccgg gatctgtcca cgtttgagac ggacttgtcc gtcacggaac gccttcttcc
    24481 gctggtcccg ccgggcatcc cggtgatcgg tgagagcggc attgcgtctc ccgatgatgt
    24541 ggtccgcctg aggagagccg gagtcagcgg ggttttggtc ggagaatgtc tgatgcgcca
    24601 agaagatccc gtgacggccg tccgggagtt gatcggtgcg ggagtggatt gtgccggatg
    24661 aagagcatcc atgtgaaatt gtgcggattt cgcaggccgg aagaggtgcg ggaagcggcc
    24721 gctcttgagg tggaccggat cggattcatt ttggcccggg gccgtcgcag aagcgtcgaa
    24781 ccggaagtgt ttccggatct ggtacgggag gcgggcccgg accggtccgt cggggtgctg
    24841 gtggatcccg caatggagga gatcggaact tggctggacc gtgcaacatg gaaaacggtt
    24901 caactgtgcg gaggggagtc tcccgacttc tgccggcggg tgaaagaaac gttcgggctc
    24961 tccgtcatca aggtgtttca tgtgtgccaa tgcgggaaac agcccgcgtt tccgctggat
    25021 gcatatgcct cttccgtgga tgcttttttg ctggacgcct tcgcgccgga gggaggtggt
    25081 ggagggaaga cgtttgactg gaacctcatc cctcccgttc tggaccggtg cagacgcttg
    25141 ggaaaaccac tgtgggtggc cggcggattg acggcgagca atgtcggaaa gctgcttggc
    25201 cggatccggc ctgacggggt ggacgtctcc ggcggaatcg aaagaaacgg caaaaaatgc
    25261 cccgaaacca tgaagcggtt cctgaaagag gtgagaagcc atgaagacac ttgacgagca
    25321 aatgacggaa gcggcgggga agttcggcag gtttggcgga agatttgttc cggaaacgct
    25381 gatgagtccc ctgtcggaag tggaaagggc gttcggggat gcgatccggg acgaagaatt
    25441 catgcagaaa tggtcgggac tgttgaggaa cttcagcggc cggccgaccc ctctcacata
    25501 cgccgcacgt ttgaccgaac atgcgggagg cgcccgcatc ttcctcaagc gggaagatct
    25561 caatcacacc ggcgcacaca agatcaacaa tgcattgggc caagcgcttc tggcgaaacg
    25621 gatgggcaag aaaaaggtac tggccgaaac gggagcgggg caacacgggg ttgcatccgc
    25681 caccgccgcc gccctgctgg ggcttgcatg tgacgtgtac atgggagaag aagacatgtg
    25741 tcggcaggaa ctgaacgtgt tccggatgca gcttttgggg gcccgcgtga ttccggtgac
    25801 gacgggcagc cggactctga aggatgccac caatgaggcg ctcagggcgt ggtcccgtca
    25861 agcggaaacg gcctattatc tcctcggatc cgcggtgggg ccccatccgt atccgcggat
    25921 ggtgaaaacg tttcaacggg tgatcggtga cgaggcgagg gcgcagcttt tggaggcgga
    25981 aggccgtttg ccggatcatg ccgttgcctg cgtgggggga ggaagcaacg cgatcgggct
    26041 gtttgccgcg tttctggatg atcggtccgt ttcactgcac ggggtggaag cggccggaga
    26101 aggacttcat accggacgtc acgcggcggc ggtgtgtcag gggagaccgg gaatcctgca
    26161 cggcatgcac agtttgtttt tgcaggatga gacgggtttg gtaaaacagg cccattccgt
    26221 ttccgccgga cttgattatc cgggcgtggg gccggagcat gcgtttcttc acgagacggg
    26281 gagggtgcgc tatgcggcgg tgacggacag ggaagcgctg catgccgtgg atctcctttg
    26341 caggctggag ggaatcctgc cggccctcga atcggcacat gcggtggctg aagctgtgaa
    26401 gatcgcttcc cgcttgccga aggacaaggt ggtgctggta tgtctgtccg gtcggggaga
    26461 caaggatgtg ggtaccatcc gggatgcatg gggagggaag gcgcatgcat cgtttgaaga
    26521 cgtcgtttga aaaacccgga agccgggtca tcccgttttt gatggcgggg gatccggatc
    26581 cgggcaccac gctggaattg atgcggctgc tcgcggaaga gggggtgacc gccattgaac
    26641 tgggggttcc gttttccgat ccggtggcgg acggccccgt gatccaggcc gcatccggac
    26701 gtgcgcttga ccggggcgtc cggttgccgg acgtgtttcg gctcgggaga tcttttcgcg
    26761 aaagcgatcc cgacactccg ctcattctct tctcctatgc caatccgatc tattgtcacg
    26821 gtgtggagcg ggcggcggag gaatcggccg cttgcggctt tgacggatgg atcattcccg
    26881 atgtgcctgt ggaagagagc ggaccttgga aaaaggcggc ggaaagtcgg gggttggccc
    26941 tgatccccct tgtggctccc acgtcgtcgg agcggattcg ccgcatcgtc gcggaagcat
    27001 ccgggtttgt atactgtgtg tcttccctcg gaacgaccgg tgtcaggtcc cggtttgacg
    27061 accgtctgga gcggacggtg gcggcggtga aagacacggt gcccttgccg gtggcggtcg
    27121 ggttcggggt ttccgggaga gaacaaagcc ggcggatccg ggagtttgcc gacgcggtgg
    27181 tgataggaag cgcgctcgtc aagcgaatcc acgatgctcg gtttcttctg tccgaaggtt
    27241 cgaagcgacg ggaagccatg gaggcgattc gggcatttgt cagagaagtc aaatcagagt
    27301 aagatagagg caaaaaggtc gcgagaggag acccgttcat gaagccgaaa tcaaccgtgc
    27361 aaggcttgcc tgtctatcag c
//
