LOCUS       NZ_CP034118            20900 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Staphylospora marina strain SCSIO 07575 chromosome, complete genome.
ACCESSION   NZ_CP034118
VERSION     NZ_CP034118.1
KEYWORDS    RefSeq.
SOURCE      Staphylospora marina
  ORGANISM  Staphylospora marina
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Staphylospora.
REFERENCE   1  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Staphylospora marinus gen. nov., sp. nov., a novel member of the
            family Thermoactinomycetaceae, isolated from a deep-sea hydrothermal
            vent sediment in Pacific Ocean
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2018) CAS Key Laboratory of Tropical Marine
            Bio-Resources and Ecology, South China Sea Institute of Oceanology,
            No. 164 West Xin Gang Road, Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: FALCON v. 0.3.0; Celera Assembler v. 8.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1382.0x
            Sequencing Technology             :: PacBio Sequel; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003856495.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 03:57:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,772
            CDSs (total)                      :: 2,679
            Genes (coding)                    :: 2,660
            CDSs (with protein)               :: 2,660
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 6, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 4 of 19
            Pseudo Genes (incomplete)         :: 16 of 19
            Pseudo Genes (internal stop)      :: 0 of 19
            Pseudo Genes (multiple problems)  :: 1 of 19
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1106745
            Orig. end                         :: 1127645
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034118.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20900
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20900
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20900
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10900](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            246..452
                     /gene="spoIIIAC"
                     /locus_tag="EG886_RS05530"
     CDS             246..452
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018886390.1"
                     /locus_tag="EG886_RS05530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_124727202.1"
                     /transl_table=11
                     /translation="MPYHLDSVFQIAGIGIIVAMIHTVLKQMGKEDFAHWVTLFGFVVV
                     LFMVAMLVQDLFQTIKNVFLFRM"
     gene            468..857
                     /gene="spoIIIAD"
                     /locus_tag="EG886_RS05535"
     CDS             468..857
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007725724.1"
                     /locus_tag="EG886_RS05535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_124727203.1"
                     /transl_table=11
                     /translation="MEIIQVVGLGLVTTFLVLVIKEQKPVFAFLLATFVGIVIFLSLVT
                     KVGEVIGILENLARHAKVNGLFMETVLKIIGIAYIAEFGAQVTRDAGQGSIASKIELAG
                     KVLIMVMAIPIVTVIIETIVQILPA"
     gene            871..2103
                     /gene="spoIIIAE"
                     /locus_tag="EG886_RS05540"
     CDS             871..2103
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: protein motif:HMM:TIGR02829.1"
                     /locus_tag="EG886_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_124727204.1"
                     /transl_table=11
                     /translation="MRPIPKRHGEHERRVSAAGACRCGWLLLLTALLWLSFAREAIAVE
                     PGEIGDRLIREQLNRLQVREVEMFWKEIHGEYGRFMEGTEGGIFDQLLSGKDLTFENVL
                     SGFARFFFREILYNGKLLGSILILTVLSMLLRTLQTAFEQNQVSKVAYAIVFMVLITLA
                     VNSFSAAVDAAKTAIGRMVDFMLAIVPLLLTLLVSMGNAGSAALFHPLIVFMIHVVGTF
                     IYTVIFPLLFFSTILSLVSCLSDKYKVNQLAGLLRKISLSLLGGLLAVFLGVISIQGAS
                     AAVADGVALRTAKYITGNFVPVVGRTISEAADTVMGASLLVKNTVGLAGVIILLLICAF
                     PALKILSLAFIYNFSAAVMQPLGNSPVVEALEIIGKTLLYIFAALATVGLMFFLALTIM
                     ISAGNISLMMR"
     gene            2113..2754
                     /gene="spoIIIAF"
                     /locus_tag="EG886_RS05545"
     CDS             2113..2754
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: protein motif:HMM:NF021121.4"
                     /locus_tag="EG886_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_124727205.1"
                     /transl_table=11
                     /translation="MVEWLGDWIRQIVILVLIAAFLDLLLPSGSMDRYVKLVMGLLIVM
                     AMLSPVFRLLDREPDLAAIRLKPDTDPPVESMENIQSRGEQMEEAANRQVRDEAERRLE
                     STLSSEVAGKFKVEVVKADVTMSESRTDDMEIKQVELRIRSREPEASPAEQETVRPVEP
                     VNIMVGSLSDGPDAAGKSEETEQTRRIARWVAEYLGLSESLVTVTEVRTL"
     gene            2772..3374
                     /gene="spoIIIAG"
                     /locus_tag="EG886_RS05550"
     CDS             2772..3374
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: protein motif:HMM:TIGR02830.1"
                     /locus_tag="EG886_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_124727206.1"
                     /transl_table=11
                     /translation="MWDKWFKPKENGKNRIGWLVIVGLAGVGAMILSSFVQVREDPWPP
                     QQQQAESDPNAREAVAATDRISTMQEYEQRYQEQLEDVLGKIVGVDDVSVIVNLDSSEE
                     EVVQLDVRESQQVTTETDKSGGERKITQNTHDKKTAYSRGENGEKPVVIKRLKPKVRGV
                     LVVARGVEDLRVKAIVIEAVHRTLDVPMHRISVLPKG"
     misc_feature    3384..3398
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            3391..3951
                     /locus_tag="EG886_RS05555"
     CDS             3391..3951
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024097.4"
                     /locus_tag="EG886_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIIAH-like family protein"
                     /protein_id="WP_124727207.1"
                     /transl_table=11
                     /translation="MSINKQTVWLVTMLSLMVVLSAYYLLTGPVEPVQETVKSSDLPGK
                     GITVDIKPVEKPEAGEKQAKEAVKGESDFFVGYQLQRSTLRQKMTEEYMKVLTDPEASK
                     QEIEEAQKKIEQLMKTDNTETVLEELIRKEGFRDAVVMSNSRHVDVIVQSDNLSRAQAV
                     KLISLVKQHMDVDPVDVSVAYKP"
     misc_feature    4082..4091
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.08"
                     /tool="antismash"
     gene            4360..4881
                     /gene="accB"
                     /locus_tag="EG886_RS05560"
     CDS             4360..4881
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708358.1"
                     /locus_tag="EG886_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_124727208.1"
                     /transl_table=11
                     /translation="MAFKMHEIRELIRLIDESSIEEFEIDNEGAKVVIKKAGGREAVLQ
                     TPAPAVPQTAPVTPAVPPAPTPAVSSAPAPAPEPKVESPAASDDLNDPTLHKIVSPMVG
                     TFYRAPAPDADPYVKEGDTVDEKTIVCIVEAMKLMNEIEAECRGTIVKVLVENGQLVEY
                     GQPLFLVKTS"
     gene            4904..6265
                     /gene="accC"
                     /locus_tag="EG886_RS05565"
     CDS             4904..6265
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007786381.1"
                     /locus_tag="EG886_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_124727209.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 3e-08, bitscore:
                     31.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 7e-11, bitscore: 39.3,
                     seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.4e-16,
                     bitscore: 56.6, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLVANRGEIAVRVIRACRELGISTVAVYSEADRDALHVTLA
                     DEAYCIGPAPSRDSYLNMTNLMSVATLVGADAIHPGFGFLSENADFAELCAACNITFIG
                     PSPEAIAKMGDKTTAKNTMKKAGVPTVPGTDGIVEDLDEAAAVAAEIGYPVIVKATAGG
                     GGKGMRVVHDEEELKRAITLAQKEAEANFGNPGVYIEKFLVEPRHVEIQVLADNHGNCI
                     HLGERDCSIQRRYQKLIEEAPSPAVDPKLRERMGQAAVAAARSVNYSGAGTVEFLLDKD
                     GNFYFMEMNTRIQVEHPVTEMITGIDLVKWQLRVAAGEKLTIRQEDVRLDGWAIECRIN
                     AERPDKNFMPSPGTINFYLPPGGNGVRVDSACYAGYKITPFYDSMIAKLIVWGEDRREA
                     IDRMNRALREFAIDGVHTTIPFHLKLLNHPKFISGDVHIQFLENINLDEETDGE"
     gene            6262..6642
                     /locus_tag="EG886_RS05570"
     CDS             6262..6642
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019532744.1"
                     /locus_tag="EG886_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="WP_124727210.1"
                     /transl_table=11
                     /translation="MNELYHYESEVSGKVEIAPEVIQTIAGIAASNVEGVAAMSGGVEW
                     LGRKNPKRGIRVELGERLSIELSVTVRYGYHIPDIGRKIQNEVKSAVESMTGLQVDEVT
                     VRVEGIKFQQTEKGETEPSRVK"
     gene            6759..7181
                     /gene="nusB"
                     /locus_tag="EG886_RS05575"
     CDS             6759..7181
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013074787.1"
                     /locus_tag="EG886_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_124727211.1"
                     /transl_table=11
                     /translation="MRRIARERVVQALYASEFHPEDAMGFIAEHGMELEGESRDFYFRL
                     SRGVLEHAERIDGVIRRFLKKGWTLERVSSVDRAILRMAVYELLMEPETPPAVVINEAV
                     ELAKAFGGDESGRFINGLLGSVIPKLDELRAEAGTL"
     misc_feature    complement(7270..7284)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.53"
                     /tool="antismash"
     gene            7480..8337
                     /gene="folD"
                     /locus_tag="EG886_RS05580"
     CDS             7480..8337
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005827289.1"
                     /locus_tag="EG886_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_124727212.1"
                     /transl_table=11
                     /translation="MSFQLIDGKEIAKQVRNELKAEVNRLREHGLVPGLAVILVGNHPA
                     SESYVRGKIRASEEVGIHSELIRLSETAREEELLAEVQRLNRDPNIHGILVQLPLPAHM
                     DPARVIAVIDPAKDVDGFTPLNTGNMMIGQDALKPCTPVGIIELLKRADISVAGKHVVV
                     VGRSNIVGKPVSILLQQENATVTMCHSRTKDLAYHTRQADILVAAVGRAEMITADHVKE
                     GVVVIDVGVNRREDGKLVGDVRFDEVAPLASAITPVPGGVGPMTIAMLLANTVTAAKRI
                     HGLD"
     gene            8384..9745
                     /gene="xseA"
                     /locus_tag="EG886_RS05585"
     CDS             8384..9745
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006676760.1"
                     /locus_tag="EG886_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_241154387.1"
                     /transl_table=11
                     /translation="MVGKSGSIWSVCDLVEYLHKRLEDDERLKRIWVEGEISNFTQNSK
                     SRHMYFTLKDGKAAIDAVMFAGNNRRLRFAPKNGDRVFVRGYVSVFISQGKMQLYVQDM
                     RLSGVGELYAAFERLKERLAKEGLFDTPKKSLPPFPKTVGVITSPTGAVIRDIIITMRR
                     RFPLASILLFPVAVQGERAPVEIARAIEVMNRLNEADVLIIGRGGGSIEELWAFNEEVV
                     VREIHRSAIPVISAVGHETDVTISDFVADCRAPTPTAAAEMAVPHLGELQKRIASLQER
                     MVMAMRGRMERLAGRLQTCVDRPVFRKPEARLEQYAQRLDVLQGRLLSGIHRMTDRESR
                     QTRELLHRLRMRDPVLMIKRHKERLKSLQMEALMNIRTQLAEGTQRTVQAAGRLDALSP
                     LKVMSRGYSLVYRMADDELVRTHEQVRPGDLLRIRLARGQLKCQVWKSEGSADE"
     gene            9738..9998
                     /gene="xseB"
                     /locus_tag="EG886_RS05590"
     CDS             9738..9998
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007129729.1"
                     /locus_tag="EG886_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_124727213.1"
                     /transl_table=11
                     /translation="MSEAKDWAALESLPFEEALRKLEETVQILERGDVPLEQAIDLFEE
                     GMRLAHVCGRKLKRAEQQVEMLVKRNEEWVREPFDPEEAAD"
     gene            10001..10900
                     /locus_tag="EG886_RS05595"
     CDS             10001..10900
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010499090.1"
                     /locus_tag="EG886_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_241154388.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.1e-61, bitscore:
                     203.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQNAIVDYIRDKAALVHGKLDEYGFGGNVPPLLLESMRYSLLAGG
                     KRIRPVLVLATCQAVGGNEEHALPFACAIEMIHTYSLIHDDLPCMDDDDYRRGKPTNHK
                     IFGEAQAILAGDALLTESFGLMASGARAAGLPADVALTVLEEASRYAGARGMVAGQVLD
                     MMSENKNVTLKEVEEVHRRKTGDLIAFSVRTGARVGGVRDGELLESLTRFAYGLGLAFQ
                     IQDDILDVIGDQKLLGKPVGSDEANKKATYPALIGLERSKRLLEEVISDAKSAISNRKD
                     LKPDRLLDIADFLLSRDR"
     misc_feature    complement(10981..10994)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.49"
                     /tool="antismash"
     misc_feature    complement(11089..11104)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.37"
                     /tool="antismash"
     gene            11707..12339
                     /locus_tag="EG886_RS05600"
     CDS             11707..12339
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124727214.1"
                     /transl_table=11
                     /translation="MALLIRKSLRWAITISLVTSTIALVLSLSSTTLMSGLSWGGGIVV
                     LLAIVTVGIVFDMLGIAATAAREDPFHAMASRKIPGAREAVGIVRRADQFSNFCNDVVG
                     DISGVISGAAAFTVVASLMASYPHLKSGQWLADILLVSFISALTVGGKALGKTISIHYA
                     QEIVFLVGKGFHWVNRKFGLNWFHVKPKKKSKRKRGVSHAPRSNQFS"
     gene            12311..14200
                     /gene="dxs"
                     /locus_tag="EG886_RS05605"
     CDS             12311..14200
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708371.1"
                     /locus_tag="EG886_RS05605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_124727215.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.5e-122,
                     bitscore: 405.3, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.6e-06, bitscore:
                     24.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLDQINSPEQLKRLPVEELPKLAEEIRTFLIESLSRTGGHLASN
                     LGVVELTIALHYLFDSPKDKFLWDVGHQAYVHKILTGRRELFPTLRQYKGLCGFPKMRE
                     SVHDVWETGHSSTSLSGAMGMAKARDLLGENWKVIPVIGDGALTGGMALEALNHIGESN
                     TDMIVVLNDNEMSISPNVGALHNHLGRLRTNPSYNKVKEEVQQLLHKIPTVGVPFARTI
                     ERIKDSLKYLLVSGVFFETLGFTYLGPVNGHDFEELLEVLRQASQTRGPVLVHVVTRKG
                     YGYKPAENDSVVYHGVGTYKIESGAFQKKSGGAPAYPAVFGETLVKLAEKDDRIVAITP
                     AMLTGSKLEKFQERFPDRCFDVGIAEQHAVTFAAGLATQGMKPVLAIYSTFLQRGYDQL
                     VHDVCRQKLNVVFAVDRAGFVGEDGETHQGVYDISFMRNQPGMVIMMPKDENEFQHMLY
                     TAVNHDDGPVAVRYTKGSGLGVPMDKEWRLLPIGKSETVRPGKDAAILAFGPMVSFAIE
                     AAERLAEEGIDVRVVNARFAKPLDAELLDELAREKIPVVTVEEGCVTGGFGSAVLEYYA
                     DKRVHDLPVRLLGVPDYYVEHGSIAQQREETGLTPEGIRGAVLELLSKNVRKA"
     gene            14210..15031
                     /locus_tag="EG886_RS05610"
     CDS             14210..15031
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016125811.1"
                     /locus_tag="EG886_RS05610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_124727216.1"
                     /transl_table=11
                     /translation="MEKQRIDVLLVEKGHFETREQARRAVMAGLVRVGGERVDKPGTRV
                     SVQLPIEVKGQIHPYVSRGGLKLEEALRVFGISVEGRVMLDIGASTGGFTDCALQRGAR
                     HVYAIDVGYGQLAWKLRQDPRVTVMERTNFRYLDPEALTGDSPDFATIDVSFISLAHIL
                     PNLSRMLQPGGEVVALVKPQFEAGREQVGKKGIVRDPRVHRQVLLSFAEMAGSLGYSLE
                     GLIPSPIRGSEGNIEFLAHLRYTGERRDNRGPDPVVISEVVEEAHRRLRES"
     misc_feature    complement(15039..15050)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.21"
                     /tool="antismash"
     gene            15141..15650
                     /locus_tag="EG886_RS05615"
     CDS             15141..15650
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS05615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124727217.1"
                     /transl_table=11
                     /translation="MLKPGDTLVLIALFAVILYFAVKNALPVKKEEASEEIRGDVPDLL
                     RREGFEPVRAREKVPLRIEFDGEHYESRVFIDYVARRDGKWYVVVTERERKPLRKSGAG
                     LRDFFLSYYSIFQPDGILYVNKETRTIKMVRFDFQGLEPESKKLPVGWIAVAAVCLGTV
                     LVWILE"
     gene            15679..16617
                     /locus_tag="EG886_RS05620"
     CDS             15679..16617
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003387251.1"
                     /locus_tag="EG886_RS05620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(+)/NADH kinase"
                     /protein_id="WP_124727218.1"
                     /transl_table=11
                     /translation="MKKRIGIILNLGKPRAIRFARDLLEALEKRRVDVVLEPEAGQALD
                     VPDRCLFVEEFPGRVDLVFVLGGDGTLLGVARRLAAHRIPILGFNVGNLGFLSEAEPDD
                     LESVIDRVLAGDYMIESRLMLKAEVVRDGETLELGNALNDVGIAKGSFGRMITCHVKLD
                     GMKLGSYSGDGLIVSTPTGSTAYSLSCGGPIVYPGIRAILLTPICPHTLTSRPMVLPAE
                     GVLEIRPSAVHREMGVTIDGQAGFPLREGDVVRVSRSPFPALLIKWHDRSFFEVVRRKL
                     QGESVTHAVQEEINESATTYQNPGNHFFHGD"
     gene            16562..17011
                     /gene="argR"
                     /locus_tag="EG886_RS05625"
     CDS             16562..17011
                     /codon_start=1
                     /gene="argR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009708376.1"
                     /locus_tag="EG886_RS05625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transcriptional regulator ArgR"
                     /protein_id="WP_124727219.1"
                     /transl_table=11
                     /translation="MKAQRHIKIREIISSMEIETQDELVEELKKAGFNVTQATVSRDIK
                     ELQLIKVPTSKGTYKYSLPTDDKRFNPVRKLKRTLQESFVHIDYSENLLVMKTLPGNAH
                     AVAALLDHLEWEEIVGTLAGDDTIFIICRHKEKAPELVARILDLM"
     gene            17025..18746
                     /gene="recN"
                     /locus_tag="EG886_RS05630"
     CDS             17025..18746
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007129735.1"
                     /locus_tag="EG886_RS05630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_124727220.1"
                     /transl_table=11
                     /translation="MLRELTIRQFAIIEHVHLRFDRGFHVLTGETGAGKSILIDALGLV
                     AGGRASSEFVRHGADRAEIEAIFEIPDEHRVRQLLIDWGYEPDDLDQLIIRREITAAGK
                     STCRINGRSVTLSMLREAGRHLLDLSGQHEHQTLLRTEEHLEWLDRYGGDELLAIRKKY
                     GELYAEYRELVRKLEELDLDGKEHAQRLDLLTFQRDEIAGAHLVPGEDEELERERTRLL
                     HAEKLLSHTAGAYEMMYGERGALDLLQESLGRLEQAAGMDESLDQVVESARQAVYLLEE
                     AVREVGRYRDGLEHEPGRLEQVEERLHLIRQLKRKYGNTIEEILSHQERVERELAELEH
                     REESQEELRAEIESLEEELGRLAGELTTLRKKAAMDLEKRVERELADLHMGSTVFHVSF
                     FRDAWRSGELTPAGRDRIEFMLSPNPGEPLKPLSRIASGGELSRILLALKVIFTGVQEV
                     HTLIFDEIDTGVSGRAAQAIAGKIAQLGQRFQVLCVTHLPQVACMADHHFLISKETVND
                     STTTRVNQLDESGRTQELARMLGGVEVTRTTLEHAEEMIRLAEEAKDAIRSNGKSG"
     misc_feature    18859..18868
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.48"
                     /tool="antismash"
     gene            18981..20339
                     /gene="spoIVB"
                     /locus_tag="EG886_RS05635"
     CDS             18981..20339
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006209383.1"
                     /locus_tag="EG886_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIVB peptidase"
                     /protein_id="WP_124727221.1"
                     /transl_table=11
                     /translation="MVRNAKLRKWFGFLLVLLLMMGSTSTLFRQFAGFPRELRLVQGEA
                     RELRLNMPVPATASVSESGILQVNGSPDTQVPVDLERPVSLRSEAIGQTSLTLKLFGKV
                     PIKHVNVRVVPKIEVIPGGQSIGVKLRSSGVLVVGHHAVQADGKEVCPAEEADIRVGDY
                     LTALDNRPIRSVRDVAEAVKEAGSSGRSLELTLMRDGKQRKVKIRPVYDKSEQMWRMGV
                     YIRDSAAGVGTLTFYDPKHRFYGALGHVIADMDTGQPIRLGEGKIVHSSVTSIDKGQSG
                     EPGEKRAIFFQEDRVVGNILKNTPFGIFGQLARKPEGGLYDRPVPVALSDQVKEGPAKI
                     LTVVEGQKVEAFDIRIVHVLKQKYPATKGLIIKVTDRRLLAKTGGIVQGMSGSPILQDG
                     KLVGAVTHVFVNDPTSGYGTHIEWMLRDAGAFEKQTADSPVGESACSFPEFVI"
     gene            complement(20547..20867)
                     /locus_tag="EG886_RS05640"
     CDS             complement(20547..20867)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024248.4"
                     /locus_tag="EG886_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_124727222.1"
                     /transl_table=11
                     /translation="MAASEKFARVARALGDPIRLNILDLLMVGYEKLEPTPPPECCNEG
                     VCVCDLQTALGMAQSKVSYHLKELKNADLVTETRVGRWHFYSLNKETLRHFHSELSRRF
                     LS"
ORIGIN
        1 ttgggaggag acgtcgctcg ggcgtgaaga aaagcaggtg ctcctccggc tgggagaagt
       61 actcggagct tcttctcgtc tggatcagct gcatcatctc gaaatggcgg aaaagcaatt
      121 ggccgtcgaa gaggacaaag ccagagacga acgcgaccgt ttcgtgaaaa tgtacagaac
      181 cgtcggcatt ctcgccgggg cgctgctggt gatcttgctg tactgagcga aaggagtgct
      241 gccccatgcc ctatcatttg gattcagtct ttcagattgc cggaatcggc atcatcgtgg
      301 ccatgattca cacggttctg aaacagatgg gcaaggaaga tttcgcacac tgggtgacgc
      361 tgttcggttt tgtggtggtg ctgttcatgg tggccatgtt ggttcaggac ctgttccaga
      421 cgatcaaaaa cgtgtttctg ttccgcatgt gacgggaggc gcaaccggtg gaaatcatcc
      481 aggtggtggg tctcggactg gtcaccacgt ttctcgtgct ggtcatcaag gaacaaaagc
      541 cggtatttgc tttcctgctg gccacgtttg tcgggattgt catctttttg tcgctggtca
      601 ccaaagtggg tgaagtgatc ggcattctcg aaaacttggc tcgccatgcc aaggtgaacg
      661 ggctgtttat ggaaacggtc ctcaaaatca tcggaatcgc ctacatcgcc gaattcggcg
      721 cacaagtgac ccgtgacgcg ggtcagggat cgatcgcttc aaagatcgaa ctggccggaa
      781 aggtgttgat catggtgatg gccatcccga tcgtcacggt cattatcgaa acgatcgttc
      841 aaatcttgcc tgcctgaagg gtgacggatc atgcgaccca tcccgaagcg acacggcgaa
      901 catgaacgga gggtctcggc ggcaggcgct tgtcgatgtg gatggctgct gctgttgacg
      961 gcactcctgt ggttgtcctt tgcacgggaa gccatcgcgg ttgaaccggg ggagatcgga
     1021 gaccgattga tccgggagca gctcaaccgg ttgcaagtcc gtgaagtgga gatgttctgg
     1081 aaggagattc acggtgaata cggccggttc atggaaggaa ccgaaggagg gatttttgac
     1141 caactgctct ccggaaagga cctgacgttt gaaaacgtcc tgtccggctt tgcccgtttt
     1201 ttcttccgtg aaattctgta caacgggaag ctgctcggca gcattctgat cctcacggtt
     1261 ctgagcatgt tgctgcgcac cctgcaaacg gcctttgaac agaatcaggt cagcaaagtg
     1321 gcctacgcca ttgtgttcat ggtgctgatc acgttggccg tcaacagttt ttccgcagcc
     1381 gtcgatgcgg ccaagacggc gatcgggcgc atggttgact ttatgctggc catcgtgccg
     1441 ctgttgctga ctttgcttgt cagcatgggt aatgccggat cagcggccct gtttcatccg
     1501 ctcatcgtgt tcatgattca tgtcgtcggt acgttcatct acacggtcat ctttccgctg
     1561 ctgttcttct ccaccatcct gagtcttgtc agttgcctgt cggacaagta caaggtgaac
     1621 cagttggcgg gacttttgag gaaaatcagt ttgtcgcttc tgggaggttt gctcgccgtt
     1681 tttctcggag tgatctcgat ccagggagcc tcggccgcgg tggctgacgg tgtcgcattg
     1741 agaacggcca aatacatcac cggcaacttc gttccggtcg tgggacgaac catttcggaa
     1801 gcggcggaca cggtgatggg cgcttccctc ctggtgaaaa acacggtcgg tttggcaggg
     1861 gtgatcatct tgctgctgat ctgcgccttc cctgcgctga aaattctgtc tctggcgttc
     1921 atctacaatt tttccgcggc cgtgatgcaa ccgctcggca acagtccggt ggtggaagct
     1981 ctggaaatca tcggcaagac gttgctttac attttcgccg cgcttgccac ggtgggactg
     2041 atgtttttcc tggcgctcac catcatgatc tccgcgggca acatctcgct gatgatgagg
     2101 taggtgagag cgatggtgga atggttgggg gactggatcc gccaaatcgt cattctcgtt
     2161 ttgatcgcgg cctttctgga tcttttgctt ccgagcggat ccatggatcg ctacgtgaaa
     2221 ctggtgatgg gactcttgat cgtcatggcc atgctttcac cggtattccg gttgctggat
     2281 cgggagcccg atttggccgc gatccggttg aagcccgata cggatcctcc cgttgagtcc
     2341 atggaaaaca tccaaagccg cggagaacaa atggaagaag cggcaaaccg acaggttcgg
     2401 gatgaagcgg agcgcaggtt ggaaagcacg ttgtcaagcg aagtggccgg caaattcaag
     2461 gtggaggtgg tgaaagcgga tgtaaccatg tccgagagcc gtacggatga catggagatc
     2521 aaacaggtcg aactccggat tcgttcccgc gaacccgagg cttctcccgc agagcaggaa
     2581 accgttcgtc cggtggagcc cgtgaacatc atggtcggtt cgttgtccga cggtccggac
     2641 gcggcaggaa agagcgagga aacggaacag acccgccgga tcgcccgctg ggtggcggaa
     2701 tacctgggac tgtccgaatc tctggtcacg gtgaccgagg tacggacact ttgaaaaggg
     2761 ggtgtggcaa tgtgtgggac aaatggttca agccgaaaga aaacggcaag aaccgcatcg
     2821 gttggttggt catcgtgggg ttggcgggag tgggggcgat gatcctgtca tcctttgtcc
     2881 aggttcgcga agatccctgg cctccgcagc agcagcaggc ggagtcggat ccgaacgcgc
     2941 gggaagccgt tgccgcgacg gaccgcattt ccaccatgca ggaatatgaa caacggtatc
     3001 aagagcagct ggaagacgtg ctcggaaaga ttgtcggtgt ggatgacgtc tccgtcatcg
     3061 tcaatctgga ttccagtgag gaagaagtgg tccaactgga cgtaagggag tcccagcagg
     3121 tgaccacgga aacggacaaa tcgggcggag aacgcaaaat cacccagaac acgcatgaca
     3181 agaaaacggc atacagccgt ggggaaaacg gggagaagcc ggtggtgatc aaacggctca
     3241 aacccaaagt ccggggggta ctggtcgtgg cccggggcgt ggaggatctt cgggtgaaag
     3301 cgatcgtgat cgaagcggtt caccgcaccc tcgatgttcc gatgcatcgg atttccgttt
     3361 tgccaaaagg atgaatgagg aggatgaagc atgtcgatca acaagcaaac cgtttggctg
     3421 gtgaccatgc tttcgttgat ggtggtgctg tcggcctatt acctgcttac ggggccggtg
     3481 gagccggtgc aggagacggt gaaatcttcg gatcttcccg ggaagggaat caccgttgac
     3541 atcaaaccgg ttgaaaaacc cgaagctgga gaaaaacagg ccaaagaagc ggtcaaagga
     3601 gagagtgact tttttgtcgg ctatcaactt caacgcagca ccctccgcca aaaaatgacc
     3661 gaggaataca tgaaagtgtt gaccgacccc gaagcatcca agcaagagat cgaggaagcc
     3721 cagaaaaaga tcgagcaact gatgaaaacg gacaacaccg aaacggttct ggaggaattg
     3781 attcgcaaag aaggtttccg cgatgccgtg gtgatgtcca attcccggca cgtcgatgtg
     3841 atcgtacagt ccgacaatct ctcccgcgcg caggccgtca aattgatcag tctggtgaaa
     3901 caacacatgg acgtcgatcc ggtggatgtg tcggtcgctt acaaaccttg atttgacaac
     3961 atcttccccg atcatccgga ccatgagcgg gagaccggtt tgatcatggg cgggatcgga
     4021 aagggaaaag gaacgaatgc cgggaggaag cgtcaacgac ccgtgaatcc cccggttttt
     4081 ttgttttttt cgattgtggg ctggtattgg gagttgatca cagatcggag gacctgtagg
     4141 atggtgatgt gggtaccgcg gccgtggaac cgcttccggc atgtttcctc cggtcggggg
     4201 gaacactgaa gcgaaagaga ggttcgatcg cggaaatcca tgtccccgcg cggttccgcg
     4261 gaatggacag gggtggtcaa accaccgaaa aaaaggtatg cttaacagtg tcatcatgaa
     4321 tggtttgatt cccatgccga agtgcgagga gtgaacaaga tggcattcaa aatgcatgaa
     4381 attcgcgaat tgatccgtct gattgatgaa tcttcgattg aagagtttga aattgacaac
     4441 gaaggagcca aggtggtcat caagaaagcg ggcggccggg aagccgttct ccagactccc
     4501 gcgccggcgg tgccacagac cgcacccgtg actcctgcgg ttcctcccgc tccgacaccc
     4561 gcggtttcct ccgcccccgc tccggctccg gagccgaaag tcgagtctcc ggccgcgagt
     4621 gacgatctga acgatcccac gctacataaa atcgtttctc cgatggtggg taccttctat
     4681 cgcgcccccg ctccggatgc cgatccgtac gtgaaagagg gcgacacggt cgatgaaaaa
     4741 accattgttt gcatcgtgga agccatgaaa ttgatgaacg agatcgaagc ggagtgccga
     4801 ggcaccatcg tcaaggtcct ggtggagaac ggtcagctgg tcgaatacgg gcaaccgctc
     4861 ttcctggtca agacaagctg atctgccgga gggggaaatg cagatgttca agaaggtact
     4921 ggttgccaac cggggtgaaa ttgcggttcg tgtcatccgg gcctgccggg agctcggcat
     4981 ttcgaccgtg gcggtctact cggaagcgga ccgggacgca ctgcacgtga ctctggccga
     5041 tgaagcatac tgcatcggtc ccgctccgtc ccgggacagt tatctcaaca tgaccaatct
     5101 gatgagtgtg gccactctcg tgggagcgga tgccattcat cccgggttcg gattcctgtc
     5161 ggaaaacgcc gatttcgccg aactttgcgc cgcatgcaac atcacgttca tcggtccttc
     5221 tccggaggcc atcgccaaga tgggcgacaa gacgacggcc aaaaatacga tgaaaaaagc
     5281 cggcgttccg acggttcccg gaaccgacgg aatcgttgaa gacctggacg aagcggcggc
     5341 ggtcgccgcg gagatcggtt atccggtgat cgtgaaggcc acggcgggcg gcggaggcaa
     5401 aggaatgcgc gtggtccacg atgaagaaga actgaaacgg gccattaccc ttgcccagaa
     5461 agaagccgaa gccaacttcg gcaacccggg ggtctacatc gaaaaatttc tggtggaacc
     5521 ccgtcacgtg gagattcagg tgctggccga caaccacggc aactgcattc acctcggtga
     5581 acgggattgt tccatccaac gccgatacca gaaactgatc gaggaagctc cttctcccgc
     5641 ggtcgatccc aagttgcgtg aacggatggg gcaggcggcg gtggccgcgg cccgatcggt
     5701 caattattcg ggagcgggaa cggtggaatt tctgttggac aaagatggga atttctactt
     5761 catggagatg aatacccgga tccaggtgga gcatccggtg accgagatga tcaccgggat
     5821 tgatctggtc aaatggcaat tgagggtggc tgccggtgaa aaactcacca tccgccagga
     5881 agacgtccga ttggacggat gggccattga atgccggatc aatgccgagc ggccggacaa
     5941 gaacttcatg ccgtcacccg ggacgatcaa tttttatctg ccgcccggcg gcaacggcgt
     6001 gcgcgtcgac agcgcctgct atgccggata caagatcacc ccgttttatg attcgatgat
     6061 tgccaagctg atcgtgtggg gcgaggatcg ccgggaggcg attgaccgta tgaaccgggc
     6121 actcagggaa ttcgccatcg acggagtcca cacgaccatt ccgttccacc tgaaactgct
     6181 gaaccacccc aaattcatat ccggggatgt tcatatccag tttcttgaaa atatcaatct
     6241 cgatgaggag acggatggcg aatgaatgaa ctctaccatt acgaatccga agtttcgggc
     6301 aaagtggaga tcgctccgga agtgattcag accattgccg gaatcgccgc ttccaatgtg
     6361 gaaggagtgg cggcgatgag cggtggcgtg gaatggctcg ggcgcaaaaa tcccaagcgg
     6421 gggatccggg tggaactggg ggagcgcctc tccattgagc tgtccgtcac ggtgcgctac
     6481 ggttaccaca ttcccgatat cggacggaaa atccagaatg aggtcaagtc ggcggtggag
     6541 agcatgacgg gcctgcaggt ggatgaagtg accgtccggg tggagggaat caagttccaa
     6601 cagacggaaa agggcgagac ggaaccgtcc cgggtgaaat gagcacctgc gggccggttt
     6661 ccgcacaggc aaccgcaccg ctcgcctgac gtcaagaccc attacgtttc cgaagtccgg
     6721 gccggatcgg ctcggcttcg tttttggagg caagatctat gagaagaatc gcgagggaac
     6781 gggtggttca ggcactttat gccagtgaat tccatccgga agacgccatg ggattcatcg
     6841 ccgaacacgg catggaactg gagggagaat cccgggattt ctacttccgg ttgtcccgtg
     6901 gagttctgga acatgccgaa cggatcgatg gagtgattcg tcggtttttg aaaaagggat
     6961 ggactctgga gcgcgtctct tcggtggatc gtgccatctt gcggatggcc gtgtatgaat
     7021 tgctgatgga gcctgaaacc cccccggccg ttgtcatcaa cgaggcggtg gaactggcaa
     7081 aggctttcgg aggcgatgag tccggccgtt tcatcaacgg gcttttgggc agtgtgattc
     7141 cgaagctgga tgaattgcgt gccgaagcgg gaactctctg agcggatcgc gtcaaaaacg
     7201 gtttcctttg cgtgatttgt catttccggc gttgtcgaaa cggaacatca tccgacgccg
     7261 cggacgggga atgttcggaa aaaggctgct gtctcggggt gcgaagcttt cgtgagagag
     7321 agttttcaag tggtttttcc ggtcggtttc atttgctgtc agcccgcttg ggacaaggat
     7381 tttcgtcggt tttcggcgcc gaactttaca cccttacagg aaaaggataa acttgaacaa
     7441 taacagtaat ttctcaatga atattagggg tgtggcgcca tgtcgtttca gctgatcgac
     7501 ggaaaagaga tcgcaaagca ggtcagaaat gaactgaaag cggaagtgaa ccgtctccgg
     7561 gagcatggat tggtacccgg gttggccgtg attctggtcg ggaatcaccc ggcgtccgaa
     7621 tcctatgttc ggggaaaaat ccgggcttcc gaagaagtgg gcattcactc cgagctgatt
     7681 cgcctgagtg aaaccgcacg ggaagaagaa cttctcgcgg aagtccaaag actcaaccgt
     7741 gacccgaaca tccacggaat cctcgtgcag cttcccctgc ctgcccacat ggatccggcc
     7801 cgcgtcatcg ccgtgatcga cccggccaag gatgtcgacg ggttcacccc gttgaacacg
     7861 ggcaacatga tgatcggtca ggatgcactc aaaccatgca caccggtcgg gatcatcgag
     7921 ttgctcaaac gcgccgacat atcggtggcc ggaaaacatg tggtggtggt gggacggagc
     7981 aatatcgtcg ggaagcccgt gtccatcctg cttcaacagg aaaacgccac ggtgacgatg
     8041 tgccattccc gaacgaagga cttggcatat cacaccagac aggcggacat tctggtagct
     8101 gcggtgggaa gagccgagat gatcaccgcc gatcatgtaa aggaaggagt ggtggtcatc
     8161 gacgtgggcg tcaaccggcg ggaagacggg aagctcgtcg gggatgtgcg ctttgacgaa
     8221 gtggcgccgc tggcttccgc gatcacccct gttcccggcg gagtgggccc gatgaccatt
     8281 gccatgctcc ttgcgaacac cgtcacggca gccaagcgaa ttcacgggtt ggattgacgg
     8341 gtcggaagaa acggcgaaaa aattgcggac cggagggaca cacgtggtcg gaaaatccgg
     8401 gagcatatgg tctgtctgtg atctggtcga atacttgcac aaaagactcg aggacgatga
     8461 acggctgaag cggatttggg tggaagggga gatctccaat ttcacccaaa acagcaaaag
     8521 ccggcacatg tatttcacgc tcaaagacgg caaggccgca atcgacgcgg tgatgttcgc
     8581 cggcaacaac cgtcgcctcc gatttgctcc caaaaacggg gaccgggtat tcgttcgcgg
     8641 atatgtgtcg gtgttcatca gtcagggaaa gatgcagctg tacgttcagg acatgcgact
     8701 cagcggcgtg ggagagctgt atgcggcttt tgagcgactg aaagaaaggc tggcgaaaga
     8761 aggtctgttt gacaccccca agaaatctct tccgccgttt ccgaaaacgg tgggagtgat
     8821 cacttctccc accggggcgg tgatccggga catcatcatc accatgcgcc ggcggtttcc
     8881 attggcttcc attctgcttt tccccgtggc ggtgcaggga gaacgtgcgc cggttgaaat
     8941 tgcccgggcg atcgaagtga tgaaccgtct gaatgaggcg gacgtactca tcatcggccg
     9001 cggcggcggt tccatcgaag aactttgggc gttcaatgaa gaagtggtcg ttcgcgaaat
     9061 tcatcgctcg gcgattcccg tcatctccgc cgtcggccat gaaacggacg tcaccatcag
     9121 cgacttcgtg gcggattgcc gggctcccac tcccactgcg gccgctgaaa tggcggttcc
     9181 ccatctcggg gaattgcaga agaggatcgc ttcgctgcag gaacggatgg tgatggccat
     9241 gcgcggccgg atggagcgtc tcgccggacg actgcaaaca tgcgtcgacc ggcccgtgtt
     9301 ccgaaaaccg gaagctaggc ttgagcagta cgctcaacgc cttgacgttc tgcaaggtcg
     9361 gttgctgagt gggattcacc gtatgacgga cagggaatca cgccagacgc gggaacttct
     9421 tcaccggctt cgaatgcggg atccggtgct gatgatcaag cggcacaaag agcggctgaa
     9481 atcccttcag atggaggcgt tgatgaacat ccggacccaa ttggccgaag gaacgcaacg
     9541 gaccgtgcag gcggccggtc gactggatgc tctcagtcct ctgaaggtca tgtccagagg
     9601 atattcattg gtttaccgga tggccgacga tgagttggta cgcactcacg agcaggtgcg
     9661 gccgggggat ttgttgagaa tccgcttggc ccgtggacag ttgaaatgtc aggtatggaa
     9721 atcggagggg agcgccgatg agtgaagcca aggattgggc cgctttggag tctctgccgt
     9781 ttgaagaagc tcttcgaaaa ctggaagaaa ccgtgcagat tctggaacgg ggagatgttc
     9841 cgctggaaca ggccatcgac ttgtttgaag aaggaatgcg cctcgcccat gtatgcggtc
     9901 ggaagctgaa gcgggcggag caacaggtgg aaatgcttgt gaaacggaac gaagaatggg
     9961 tcagggagcc ttttgacccg gaggaggcag ccgactgaac gtgcaaaacg ccattgtgga
    10021 ctacatccgt gacaaagcag cgttggttca cggaaaattg gacgagtacg gattcggcgg
    10081 aaatgttccg ccgcttcttc ttgaatcgat gagatattct cttctcgccg gcggaaagag
    10141 gattcgtccg gtgttggtgc tggcgacttg ccaggctgtc ggtggaaatg aagaacatgc
    10201 actccctttt gcctgcgcaa tcgaaatgat tcatacgtat tcgctgattc atgatgacct
    10261 tccgtgcatg gacgatgatg actaccgacg gggcaagccg accaatcaca agatcttcgg
    10321 agaagcccag gccattctgg cgggagacgc cctcctgacg gaatccttcg gcctgatggc
    10381 ttcgggagca cgggcggccg gacttcccgc cgatgtggca ctgaccgtgc tggaagaggc
    10441 gagtcgctac gcgggagcac ggggaatggt tgccggccag gttctggaca tgatgtcgga
    10501 aaacaagaac gtgacgctga aagaagtgga agaggttcac cggagaaaaa ccggggatct
    10561 gatcgcgttt tccgtccgaa cgggagcacg ggtcggcgga gtgcgcgacg gagaattgct
    10621 cgagtctctc acccgttttg cctacggttt gggactcgct ttccagattc aggatgacat
    10681 tctggacgtg atcggagatc agaaacttct cgggaagccg gtcggaagcg atgaagcgaa
    10741 caaaaaggcc acctatcccg cgctgatcgg tctggaacga tccaaaaggc tcttggaaga
    10801 agtgatttcc gatgccaaat ctgccatttc aaaccggaaa gatttgaagc cggatcgttt
    10861 gctcgacatc gccgatttcc tgctttcccg ggatcgttga acccgccgtc gatccatggc
    10921 gaaggaacgg ggccggcgcc cggccacgga cgttgcgtgc caaaaccgtt gcattctgtg
    10981 ttataataag tgtaccatct catcgggtgg cgcagtattc tagtcaatcc acctcctctg
    11041 aaggcggggc taaaaatccg ccaaagggca catcgatgaa gttcttggtg ttggctttcg
    11101 gcgcccagcc gggggctgat gctgggagtt aaggttgaag ggcgatccgc aaaggcatgc
    11161 gggcgttgac ccttcttccg cggaggccca agtgcgtcgt gagaaggcga aacggatcgc
    11221 gatggcttgg gggatgaacc tgcattcggg cagtcacctg ggtgcagcgt agcctgcctt
    11281 gagtggcagg gcggggatga cttccctttc ccgggacgtc tgaaagctcg tgctgcaaaa
    11341 gaggctagga ggttggctcg gattgttgag gaaaactcct agactgtttg ccgcatggca
    11401 tggcggttcg gggattaaag tgcggactca gtggcaatcc agtccggcgg atggcgacac
    11461 cgtcgaagaa gttgtaaagg gaaaccgcca ggccggcgac ggccaggtaa cttctttggg
    11521 aaatcctact ggacctaagc cgcaaagttt acccgaaccg ttgccacccg atcgttggat
    11581 gaggcttgag ggttgccggg aagaaataca tatcgacggc accgccgtca tgcgaaaacc
    11641 ggtccgccga gaccggcatt ttcatggatg cctgcgaaga ggccgggaat cgaggggaat
    11701 cattctatgg cattattgat ccgcaagtca cttcgttggg ccatcaccat cagcttggtc
    11761 acttccacca tcgcgctcgt gttgtcgctt tcgtccacca ctctcatgag cggcctctcg
    11821 tggggcggag ggattgtggt tttgctcgcc atcgtgacgg tggggatcgt gtttgacatg
    11881 ttgggcatcg ccgcaaccgc cgcacgcgaa gatccgtttc atgccatggc gtcccggaaa
    11941 ataccggggg ccagggaggc ggtcgggatc gttcgtcggg cggaccaatt ctcgaatttt
    12001 tgcaatgatg tcgtggggga catcagcggg gtgatcagcg gtgcggctgc gtttacggtc
    12061 gtggcctccc tgatggcgtc atacccgcat ctgaaatcgg gacaatggtt ggccgatatc
    12121 ctgctcgttt ccttcatatc ggcgctgacg gtgggaggaa aagcgctcgg caaaacgata
    12181 tccatccatt acgcgcaaga aattgtcttt cttgtgggca agggattcca ctgggtcaac
    12241 cggaaattcg gcttgaactg gttccacgta aagcccaaga agaaaagtaa gcgaaagcga
    12301 ggcgtttccc atgctcctcg atcaaatcaa ttctcctgaa cagctcaaac ggctgccggt
    12361 ggaagaattg ccaaaactcg ccgaagaaat ccgtacgttt ctcatagaga gcctctcccg
    12421 gacgggtggg cacttggctt caaatctggg ggtggtcgaa ctgacgatcg cccttcatta
    12481 tctgtttgac agtcccaagg acaagtttct gtgggacgtg ggccatcagg catatgtgca
    12541 caaaattctg accggccgca gggaattgtt tcccaccttg cgtcagtaca agggcctgtg
    12601 cggattcccg aaaatgaggg aaagtgttca tgacgtctgg gaaaccggtc acagcagcac
    12661 atcgctctcg ggagcgatgg gcatggcgaa agcccgggat ttgctcgggg aaaactggaa
    12721 agtgatcccc gtgatcggcg acggagcact caccggaggg atggcgctgg aggcgctgaa
    12781 ccatatcggg gaaagcaaca ccgacatgat cgtcgtcctg aatgacaacg aaatgtccat
    12841 cagccccaat gtgggtgccc ttcacaacca cttgggaaga ctgcggacca atccttccta
    12901 caacaaggtc aaggaagagg ttcaacagct gctgcacaaa atccccacgg tgggtgttcc
    12961 tttcgccaga accatcgaga gaatcaagga cagcctgaaa tacctcctgg tttccggagt
    13021 ctttttcgaa acgctcggct tcacttatct gggaccggtg aacggacacg atttcgaaga
    13081 gttgctggaa gttctccggc aggcttccca aacccgcggt ccggtgctgg ttcatgtggt
    13141 cacgcgaaag ggatacggat acaagccggc tgaaaatgat tccgtcgtct atcacggagt
    13201 gggcacgtac aaaatcgaat cgggcgcatt ccagaagaaa tcgggaggag cgcccgccta
    13261 tcccgccgtg ttcggcgaaa cgctcgtcaa gctggcggag aaggacgatc ggatcgttgc
    13321 catcacgccc gccatgctca ccggctccaa actggaaaag ttccaggagc gttttcccga
    13381 ccgttgtttc gacgtgggaa tcgccgaaca acatgcggtc acgttcgccg cgggcctggc
    13441 gactcagggg atgaagccgg tcctcgccat ttattccacg ttcctgcagc ggggatatga
    13501 tcagctggtt cacgatgtgt gccggcagaa actgaacgtg gtgtttgcgg tggaccgtgc
    13561 cggctttgtc ggagaagacg gagaaaccca tcaaggcgtg tatgacatca gtttcatgcg
    13621 caatcagccc ggcatggtca tcatgatgcc caaagacgaa aacgagttcc aacacatgct
    13681 ctatacggcc gtgaaccacg acgatgggcc cgtggccgtc cgttacacga aaggatcggg
    13741 actgggcgta ccgatggaca aggagtggcg ccttctgccg atcggaaaat cggaaacggt
    13801 tcgtcccggg aaggatgcgg ccattctggc gtttggaccg atggtgagct tcgcgatcga
    13861 agccgctgaa cgtctggccg aagaaggcat cgacgtccgc gtggtcaacg cccgttttgc
    13921 caagccgctg gacgcggaat tgctggatga gttggcgcgg gagaagattc ccgtcgtgac
    13981 cgtggaagag gggtgcgtga ccggaggatt cggaagcgcc gttctcgagt actatgcgga
    14041 caaacgggtc catgatttgc ccgtcagatt gctcggggtt cccgattatt acgtggagca
    14101 cgggtcgatc gcccaacagc gtgaggaaac gggactgact cccgaaggaa ttcgcggggc
    14161 ggttctggaa ctgttgtcca aaaacgtacg gaaagcttga ggaagacacg tggaaaagca
    14221 acggattgac gtattgcttg tggaaaaagg ccactttgaa accagggagc aggccagacg
    14281 tgccgtcatg gccggtctgg tccgggtggg cggcgaacgg gtggacaagc cgggaacccg
    14341 ggtttccgtc caattgccga ttgaggtgaa gggacagatt cacccgtatg tttccagggg
    14401 tgggctgaaa ctggaggaag cgcttcgggt gttcggaatc tccgtggagg gacgcgtgat
    14461 gctggacatc ggtgcatcca ccggcgggtt caccgattgc gctttgcaac gcggtgcacg
    14521 tcacgtgtat gcgattgatg tcggatacgg tcagcttgcc tggaagttgc gtcaggatcc
    14581 ccgcgtcacc gtgatggaga gaaccaattt ccgttatctc gatccggaag cgctcaccgg
    14641 ggactcgccc gattttgcca cgattgacgt ctccttcatc tcattggccc acattctccc
    14701 caatctttcc cggatgcttc aacccggagg ggaagtggtg gctctggtga agccccaatt
    14761 tgaagccggt cgtgagcagg tcggaaaaaa agggattgta cgggatcctc gggttcaccg
    14821 ccaagtgctg ctctcctttg cggaaatggc cggttcgctc ggctactcgc tggaggggct
    14881 gattccgtcc cccatccggg gaagcgaagg aaacattgaa tttttggcac atctgagata
    14941 tacgggcgaa cgccgcgaca accgcggacc ggaccctgtc gtgatcagcg aagtggtgga
    15001 agaagcccat cgtcgcctcc gagaatcata agcatgccga atccgttttc cgtatccggt
    15061 ccggaagtga cggtgatttc cggaggaaag agggttcgtt tcgatgactg cgaattagtt
    15121 aggataagga ggggattgcc ttgttgaagc cgggcgacac cctggtactt atcgcgctgt
    15181 tcgcagtcat cctgtatttt gcggtaaaaa acgccctgcc tgtcaaaaaa gaggaagcat
    15241 cggaggagat caggggggat gtgcccgatc tgcttcgcag ggagggcttc gaaccggtgc
    15301 gagcccgtga aaaagtgccg ctccggatcg agtttgacgg ggaacattat gaaagcaggg
    15361 tgttcatcga ttacgtggcc cgccgggacg ggaagtggta tgtggtggtc accgaacggg
    15421 aacggaagcc gcttcggaag tccggagccg gactgaggga tttttttctt tcctattact
    15481 cgattttcca accggacggg atcttgtacg tcaacaagga aacacgtacg atcaagatgg
    15541 tccggttcga tttccaggga cttgagccgg aatcgaagaa gctgccggtg ggatggatcg
    15601 ccgtggcggc ggtatgcctg ggaacggttc tggtatggat actggaatga accggatgtg
    15661 actgatggag ggacggtttt gaaaaaacgc atcggcatca tcctcaacct cggcaagccc
    15721 agggcgatcc ggtttgcccg cgatctcctg gaggcccttg aaaaacgcag ggttgacgtc
    15781 gttctggaac cggaagcggg acaggcgctg gatgtgcccg accggtgtct tttcgtggag
    15841 gaattccccg ggagggtgga tctggtcttc gtgctcggag gagacggaac cttgctgggg
    15901 gtggcgagga gattggccgc gcatcggatt cccatcctcg gattcaatgt gggcaacctg
    15961 ggctttctgt ccgaagccga acccgatgat ttggaaagtg tcatcgatcg ggtgttggcc
    16021 ggtgattaca tgatcgaaag ccgcctcatg ctgaaggcgg aagtggtcag ggacggcgag
    16081 acacttgaat tgggcaacgc tttgaacgac gtgggaatcg ccaaagggtc gttcggtcgg
    16141 atgatcactt gccacgtgaa gctggacgga atgaagttgg gttcgtattc cggagacggt
    16201 ttgattgttt ccacgcccac gggctccacc gcctattcgc tctcctgcgg agggcccatc
    16261 gtctatcccg gcatccgggc cattctgctc actcccatct gccctcatac ccttacttcg
    16321 cggcccatgg tcctgccggc ggaaggggtt ctagagattc ggccgtccgc cgtacaccgg
    16381 gaaatgggag tcaccattga cggtcaggcg ggttttccct tgcgggaagg ggatgtggtg
    16441 agagtgagcc gttctccttt ccccgctctt ctgatcaaat ggcatgatcg ttcatttttt
    16501 gaggtcgtac gcaggaaact acaaggagaa agcgtgacgc atgcggttca ggaggaaatc
    16561 aatgaaagcg caacgacata tcaaaatccg ggaaatcatt tcttccatgg agattgaaac
    16621 acaggatgaa ctggtcgagg aactgaaaaa ggcgggattc aatgtcaccc aagccacggt
    16681 ttcccgcgac atcaaggaat tgcaactgat caaggtcccc acttccaagg gaacctacaa
    16741 atactccctg cccacggatg acaagcgttt caacccggtg agaaagctga agcgaacctt
    16801 gcaggagtcc ttcgttcaca tcgattacag tgaaaacctg ctggtcatga aaacgttgcc
    16861 cggcaacgca catgcggtgg ccgccctttt ggatcacctt gaatgggagg aaatcgtcgg
    16921 taccctcgcg ggggacgaca cgattttcat catttgccgg cacaaggaaa aggcgcccga
    16981 attggtggca cgcattctcg atctcatgta ggagaagatg catcatgctg agagagctca
    17041 ccattcgcca atttgccatc attgaacatg tacatctgag gtttgaccgc gggtttcacg
    17101 tgctcaccgg tgagaccgga gccggaaaat cgattctgat cgacgcgctg gggttggtgg
    17161 ccggcgggcg cgcctcctcc gaatttgttc gccacggcgc ggatcgggcg gagatcgaag
    17221 cgattttcga aatccctgac gaacatcggg tgagacagtt gctgatcgac tggggctatg
    17281 aaccggatga cctggatcag ttgatcatcc gacgggagat cacggcggcc ggaaagagca
    17341 cctgtcgcat caacggccgg agcgtgactt tgtcgatgct cagggaagcg ggccggcatc
    17401 tgctcgatct atccggtcaa catgaacatc agacactcct gagaaccgag gagcatctgg
    17461 aatggctgga cagatacggc ggcgacgaac tgttggccat ccggaagaaa tacggggaat
    17521 tgtatgcgga ataccgagag ctggtccgaa aactcgagga gttggacctg gacggaaaag
    17581 aacacgccca gcgtctggat ctgcttacgt tccaacggga cgaaattgcc ggcgctcact
    17641 tggttccagg ggaagatgag gaactggaac gcgaacggac ccgcttgttg catgcggaaa
    17701 agcttctgag ccataccgcc ggagcctatg agatgatgta cggtgaacgg ggagctttgg
    17761 atcttctgca ggagtccctg gggcgcctgg aacaggctgc ggggatggat gaatcacttg
    17821 accaggtcgt ggaatccgcg cggcaggccg tttatttgct ggaagaagcc gttcgggaag
    17881 tggggcggta ccgggacgga ttggagcatg aaccggggcg tctggaacag gtggaggaac
    17941 ggttgcatct gatccggcag ctgaaacgga aatacggaaa cacgattgaa gagatcctga
    18001 gtcaccagga acgcgtggaa cgggaacttg cggagctgga acatcgcgaa gagtcccagg
    18061 aagagcttcg cgccgaaatc gaatcgctgg aggaggagct gggacgcttg gcgggagaac
    18121 tcaccactct gcggaaaaaa gcggcgatgg acctggaaaa aagggtggaa cgcgaactgg
    18181 cggatcttca tatgggatcc accgtgtttc atgtttcctt tttccgggac gcctggcgca
    18241 gcggggaact gactcccgcc ggccgggacc gcatcgagtt catgctttca cccaatcccg
    18301 gagaaccgct caagccgctt tcccggatcg cttccggcgg tgaactgtca cggattttgc
    18361 tggcactcaa ggttatattc accggagtcc aggaagtcca taccctcatc tttgacgaga
    18421 tcgacaccgg cgtgagcggt cgggcagccc aagccattgc gggcaagatc gcgcaactgg
    18481 gacagcggtt tcaggttctt tgcgtcacac acctcccgca agtggcatgc atggcggatc
    18541 accactttct catctccaag gaaacggtca atgattccac caccacccgg gtgaaccaac
    18601 tggatgaaag cggacgcacc caggaactgg cccgaatgct cggcggtgtg gaagtgaccc
    18661 gaaccacctt ggaacatgcg gaagaaatga ttcgtctcgc cgaagaggcg aaggatgcca
    18721 ttcgctcaaa cggaaaatcc ggttgacaaa atttgcgttt gcaatccgtg tgattgccca
    18781 tgactgatga cttgaggcca ttggcgctgt caagtcattt tttttgcccg gaggttcccg
    18841 gcggaaccga cgtgaggatg attttttatg gatgacagga aggtttttcg cttcataaaa
    18901 gcggtggggc gtggacacct taccagtagc ggaggtcatc ctcctggcga aaggcaggcg
    18961 ggaagctcag gagagtggtg atggtgagaa acgcgaagct cagaaaatgg tttggttttc
    19021 tcctggtgct tctcctgatg atgggaagta catcgacgct gtttcgccag tttgccggtt
    19081 ttcccaggga attgcgcctc gttcagggcg aagcgcggga actccgactg aacatgccgg
    19141 tgccggccac ggccagcgtt tccgagtcgg ggattcttca ggtgaacgga tctccggata
    19201 cgcaggtccc ggttgacttg gaacgaccgg tgtcacttcg gtcggaagcc atcgggcaaa
    19261 catctctcac gttgaagttg ttcggaaagg taccgatcaa acacgtgaat gtccgggtgg
    19321 ttccgaagat tgaagtgatt ccgggagggc agtcgatcgg cgtaaaactc cgctcctccg
    19381 gggtactggt ggtggggcac catgcggtgc aagcggacgg caaggaagtc tgtcccgcgg
    19441 aggaagccga tatccgcgtg ggcgattatt tgaccgctct tgataacagg ccgatccgga
    19501 gcgtccgtga tgtcgccgaa gcggtcaagg aagcgggatc ttcgggtcgt tcccttgaat
    19561 tgaccctgat gcgcgacggc aagcagcgca aagtcaagat tcgacccgtc tatgacaaaa
    19621 gcgaacaaat gtggcgcatg ggcgtgtaca tccgggattc ggcggcaggt gtgggaaccc
    19681 tgacttttta tgatccgaag catcgctttt acggagcttt gggccacgtg atcgccgaca
    19741 tggataccgg tcagccgatt cgcttgggag aagggaagat cgtccattca tccgtgacct
    19801 cgatcgacaa gggacagtcg ggggaaccgg gtgagaaacg ggcgattttt ttccaggaag
    19861 atcgtgtggt tggcaacatc ctgaaaaaca ccccgttcgg catattcgga caacttgccc
    19921 ggaagcccga gggagggctt tacgaccgac cggtgcccgt cgctttgagc gaccaggtga
    19981 aagaagggcc tgccaaaatt ctgaccgtgg tggaaggaca gaaagtggaa gcattcgaca
    20041 ttcgcatcgt tcatgtgctc aagcaaaaat atcccgccac gaaaggactg atcatcaagg
    20101 tgaccgaccg tcgtctcctg gccaaaacgg gggggattgt ccaggggatg agcggaagtc
    20161 ccattctcca ggacggcaag ctggtgggag ccgtcacaca tgtgtttgtc aatgacccca
    20221 cttccgggta cggcactcat atcgaatgga tgcttcggga tgcaggagca tttgagaaac
    20281 agacagcgga ttctccggtc ggagagtccg cttgttcatt tccggaattt gttatttgaa
    20341 aattcggata cttgaaacgt gcaatttgag cgatcttctc cggtttttga acggaggggc
    20401 gaggcggacg ggcatggaag aacggagcct cctttcgatg gaatgattcg cgactgcgaa
    20461 acggtattcc ttcccgacat accggttaac cgaaaagccg gaattccgcc ggcccgaacg
    20521 gtgaatcggt ttgaccggcg ggagggtcag gacaggaatc gccgggacag ttccgagtgg
    20581 aaatgtcgga gtgtttcttt gttcaaagaa taaaaatgcc atctgcccac ccgtgtttcg
    20641 gtcaccagat cggcgttttt gagttctttc aagtgatacg acactttgga ctgggccatg
    20701 ccgagcgcgg tttgaagatc acagacgcag acaccttcat tgcaacattc cggaggggga
    20761 gtcggttcca gtttttcata tcccaccata agaagatcca aaatgttgag ccggatcgga
    20821 tctccgagcg cccgggcaac ccgggcaaat ttttcagaag cagccatgaa cagtcattcc
    20881 tttcctcacg tgaatgggta
//
