LOCUS       NZ_CP034118            21905 bp    DNA     circular CON 31-MAR-2024
DEFINITION  Staphylospora marina strain SCSIO 07575 chromosome, complete genome.
ACCESSION   NZ_CP034118
VERSION     NZ_CP034118.1
KEYWORDS    RefSeq.
SOURCE      Staphylospora marina
  ORGANISM  Staphylospora marina
            Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
            Staphylospora.
REFERENCE   1  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Staphylospora marinus gen. nov., sp. nov., a novel member of the
            family Thermoactinomycetaceae, isolated from a deep-sea hydrothermal
            vent sediment in Pacific Ocean
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2706111)
  AUTHORS   Wang,K.X. and Tian,X.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2018) CAS Key Laboratory of Tropical Marine
            Bio-Resources and Ecology, South China Sea Institute of Oceanology,
            No. 164 West Xin Gang Road, Guangzhou, Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: FALCON v. 0.3.0; Celera Assembler v. 8.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1382.0x
            Sequencing Technology             :: PacBio Sequel; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003856495.1-RS_2024_03_31
            Annotation Date                   :: 03/31/2024 03:57:06
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,772
            CDSs (total)                      :: 2,679
            Genes (coding)                    :: 2,660
            CDSs (with protein)               :: 2,660
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 6, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 19
            CDSs (without protein)            :: 19
            Pseudo Genes (ambiguous residues) :: 0 of 19
            Pseudo Genes (frameshifted)       :: 4 of 19
            Pseudo Genes (incomplete)         :: 16 of 19
            Pseudo Genes (internal stop)      :: 0 of 19
            Pseudo Genes (multiple problems)  :: 1 of 19
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:09:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 694569
            Orig. end                         :: 716474
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP034118.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21905
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21905
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21905
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11905](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11905
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(57..4358)
                     /locus_tag="EG886_RS03615"
     CDS             complement(57..4358)
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1194: DNA polymerase
                     III subunit alpha"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF001688.0"
                     /locus_tag="EG886_RS03615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PolC-type DNA polymerase III"
                     /protein_id="WP_164491632.1"
                     /transl_table=11
                     /translation="MSEYRNGLERLWRETHLPPEWLDTHFRDAEIREVRVNPGKKSWQI
                     RLWMPEPIDPEVWEEFIQRVRGHFQPDIQVSFQFNYERIQHEIVLQKYKHFIQKLIQEH
                     VTPAAATWFGHARWRVNQDRIEILFNNPAVLGMARQRELDRHVARFYTRITGRELPVRL
                     LAENGDDKALLDRFQEVKKREEQELVQQALAEQARASEKSAEAPENDKPVEKRIGYNIQ
                     GEPVPIRDIQDEERSVIVKGKVFKSELKELKSGRLLLTFNLTDFTNSISCKLFARDKEQ
                     AAVLKEIKNGDWLKVRGSVQFDTFTRDLVLMVNDLMEAQPVERQDTAPEKRVELHLHTS
                     MSAMDGIHDAGELIKRAAKWGHPAIAITDHGVAQAFPDAWSAGKKHGIKVIFGMEANIV
                     DDGVPIVMNADERPLLDDTTYVVFDVETTGLSAVHDVIIELAAVKIRGGEIIDRFSEFA
                     NPHRPLSQHIIELTHITDDMLKDAPEIDDVIERFLGFIDGCVLSAHNARFDMGFLQEAV
                     KRIGREPVKNPVVDTLELARFLYPGMKNYRLNTLADKLGIHLEQHHRAIYDAETTGQIL
                     WKMLLDTTEKGITHLHKLNDSIGERDLSRLRPFHAVLLVKNQVGLKNLYKLISLSHMKY
                     FHRVPRIPRSELVKHREGLLVGSGCERGELYEAALNKSPTEVEEIAQFYDYLEIQPVDL
                     NMHLVEKGLVESPNRLREANRLLVEIGEKLGKPVVATANVHYLDEHDAIFRDILHQQQN
                     NYRNTDPLPKAHFRTTNEMLEEFSYLGEEKAREVVVDNPRRIADAIEEIKLLPDGTNTP
                     VIEGADQELSEMCYKKAREWYGDPLPETVQKRLDRELTSIIKHGFAVIYLISQRLVTKS
                     LSDGYLVGSRGSVGSSFVATMSDITEVNPLPPHWRCKTCKHSEFILDGSVESGFDLPDK
                     DCPKCGTKMLKDGHDIPFETFLGFEADKTPDIDLNFGSDYQARAHAYTEELFGKEYIYR
                     AGTISKVQEKTAYGFVKKYQEQHNLHLRQAEIDRLVEGCTGVKRTTGQHPGGLMVVPQY
                     MDVHDITPVQHPADDIKSGIRTTHFDYHSISGTILKLDILGHQDPTSIRMLQDLTGVNP
                     REIPLDDPKVLGIFSSTEPLGIKPEDMNGVKTGTLGIPEFGTSFVRQMLEDTRPTKFSE
                     LVRISGLSHGTDVWLGNAQELIRSGTCTLSDTICCRDDIMLYLIYKGCPPKESFKIMEK
                     VRKGKGVSEEEAELMRQHGVPEWYIESCRKIKYMFPRAHAAAYVMMAVRIAWFKVYWPI
                     QYYATYFYRLVDDFDLNVVLKGPDAVKRKMKEIQDKGNTAPPKEKALFTTLESVLEFYA
                     RGLKFKNVDLYRSHATQFVIDGDALIPPFAAIAGVGENAAKNIMEARKDGEFLSVEDFQ
                     SRTRVSSTVVEILKEMGCLEGLPENNQLVLF"
     misc_feature    complement(4553..4569)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            complement(4632..5972)
                     /locus_tag="EG886_RS03620"
     CDS             complement(4632..5972)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037660.4"
                     /locus_tag="EG886_RS03620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_164491633.1"
                     /transl_table=11
                     /translation="MLQLDYEHAGKVIKSKRKELGLRQSDLVDDVIKLHTIRKAEKGEM
                     VSEIVLKEICRKLRLDLTELSCQAQEEKCRKADTKLTLLAIEHDIDLVGPDQALESLRS
                     LTSKTDQPWVQAYTYFLKGLCYSRKRQWLKAQNHLHKVISLSPQIPEAESSNLKAAACY
                     ELSRCSYYLNNLEQALLYVEKGLDCFLPDGDMPHIVHYLKIGQIIYLEKMDRNEEALNY
                     LDELWQEFESIRVPDIHLTMYEVRACLMIKHGLYENAARICMEALEWSRLYGNVDRSFE
                     LWTTLGEACLGIGDLAKAERCFLMALKLEKKITRKHLLVSTHTKLGLLYLKTGQTGDAE
                     KILAKAVQLGKKTRNDFRHCEALIFLGDCHVRQDQTDKAMQCYRQALSIAEKHRLKEQE
                     QKILVKLARCCEKDDPKTSEKYKERFFRLHVQLIEGGEEDEAHRALH"
     misc_feature    complement(5965..5979)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.06"
                     /tool="antismash"
     misc_feature    complement(6215..6228)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 20.45"
                     /tool="antismash"
     gene            6244..6543
                     /locus_tag="EG886_RS03625"
     CDS             6244..6543
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS03625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124726864.1"
                     /transl_table=11
                     /translation="MLKVQVEGEMRKVEPFVRELARRPHVEVASEEVRVIREMEPDMVR
                     VRFRLQHQPQRRVKVVSLFDGNGREIRIPLMDVISVRMDDGRHIVTGRSFDIFA"
     gene            complement(6731..7663)
                     /gene="dnaI"
                     /locus_tag="EG886_RS03630"
     CDS             complement(6731..7663)
                     /codon_start=1
                     /gene="dnaI"
                     /inference="COORDINATES: protein motif:HMM:NF006505.0"
                     /locus_tag="EG886_RS03630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="primosomal protein DnaI"
                     /protein_id="WP_164491634.1"
                     /transl_table=11
                     /translation="MKKLGDVVVPFHRENRPLPDPEAMLRTLLRHPDVRRFAERHPELP
                     LDCYRRSLILLSQFVTERTSCRQCPGLEKCPNSAPGHYPVLEQYGLAISLKLTECSKLR
                     SHKESERRRSLIRSHHIPVEIRNATFESVELSAKREEAVSAAIDFCMEFENGLPDKGLY
                     LYGPFGVGKSYIAGAVTNQLASIGIASVMVHLPALVEEMKGAINENSVSDKVDALKTTT
                     VLILDDIGAETLTPWIRDDILSVIFQYRMTEHLPTIYTSNLSLDELEEHFAHTGKGGFE
                     PLKAKRLMERIRPFVRPILVEGRNRRYDQ"
     misc_feature    complement(7733..7742)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            7842..9866
                     /locus_tag="EG886_RS03635"
     CDS             7842..9866
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024642.4"
                     /locus_tag="EG886_RS03635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding domain-containing protein"
                     /protein_id="WP_164491635.1"
                     /transl_table=11
                     /translation="MEDAIRSERSRLREVLDFIDQRIEQLSNIPAYRGKDPVEIALDEK
                     RRREWGQLRRTSSQPYFGRLDFREDGSDHVSPLYIGKFGIQGDRPDELLVIDWRAPVAS
                     LFYSFGGQGDRAEYLSPDGPVEGTVYLKRNLVIRQRELERVVDTWVRGGDNLGAADEFL
                     LYRLGESKDHRLRDIVSTIQSEQDRIIRAERDKALVIQGVPGSGKTTVALHRLAYLLYR
                     YTGQMRPDRMVIFAPNRMFLEYISDVLPELGAGDVRQTTFEEWALERLEEKDRIPWAPH
                     LSAPWRGTIGFLRELDAFLDRTEEMFVPDIPFVPWNGAKLSREDIHRLHDEEYRHEPLM
                     KRKDRIHARVRRWMEGLYKEISDTDPRGIIRKEARKRFSAWARSWPSHTPLKLYRRFLK
                     ETENVRLREAGPDDLAPLLRIRQRLYGVASEERFEHVVVDEAQDFSPARFEVLKAYSRM
                     ASFTILGDLLQNIRSGRGIADWNEVIDLFDEGKASYHELNRSYRSTMEIIRFAAGIIEP
                     YRRGIRPPVPVFRSGDPVRVVKVTPERRRETVREEIRRLTASGSKTVLVAVRSEEEALR
                     LHQTLREYGIQAGLLDQTQEGYTGGISVSTVDRVKGMEFDAVVLADADAADWPDDESSA
                     RLLYVGVTRALHRLVLVTSGDLSPLVERVDPTLYESVTD"
     gene            10001..11905
                     /locus_tag="EG886_RS03640"
     CDS             10001..11905
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019638897.1"
                     /locus_tag="EG886_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_124726867.1"
                     /sec_met_domain="T2TS (E-value: 7.3e-109, bitscore: 362.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEVSLDQVNKAIHRLTGELVRRQREDGRWSFGFVNGPMTDSQFL
                     LLTNVLGMEENEIRQGIAERLLSLQQPDGTWKRFPDEREGNPSATLEACLALLYGGYRD
                     PSDRRMKKAREFLKTRAAGIGSLSRTLLPLFGHGDWKNFTRLPVEFLLLPAQSPLNFFD
                     FVGYARVHLAPVMVLADLKHSFRLKAFREIDDWLPPLGPSLMDPVEPEHFMTRDEIAIA
                     VSGAVSARRQLRRLALERAEAFMLERTEADGTLLSYASSTFLMVFALLALGYSRGHPVI
                     RRAVRGLASFARRTEGGIHIQEATSTVWDTALTLYALQEAGCPPDHPSVRRGIRYLLSR
                     QHDRPGDWMLRNPGVLPGGWGFSDINTINPDVDDTGAALRALAPAVRTGKHGEAWTRGI
                     GWLLSMQNRDGGWPAFEKNTNKLWVRLLPAREARQAFTDPSTADITGRVMHLLGSVTGW
                     TIDQPEIRRAWSWLYHHQKSDGSWYGRWGVQYIYGTWAALTGMAAVRVPRNHSAVRKGI
                     RWLLSVQNPDGGWGESCHADEKRKYVPLGMSTPVQTAWALDALIAWHDTPTPEMEKGIR
                     CLLGMLEKRDDSWAYPVGAGLAGQFNVVYESYPYVWPLVTLAHYRRKYGRLYEKPLIP"
     misc_feature    complement(12006..12023)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.53"
                     /tool="antismash"
     gene            12303..12521
                     /locus_tag="EG886_RS03645"
     CDS             12303..12521
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016047.4"
                     /locus_tag="EG886_RS03645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="WP_164491636.1"
                     /transl_table=11
                     /translation="MFAKGTDFPDVLSGGPLAARYHAPILLTPPDRMDSGVQSYLNHTQ
                     EKDFYYILGGTGSISTEVEKQLDATIQ"
     gene            complement(12770..13225)
                     /locus_tag="EG886_RS03650"
     CDS             complement(12770..13225)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012686223.1"
                     /locus_tag="EG886_RS03650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_124728644.1"
                     /transl_table=11
                     /translation="MIIRPLHNDEKPPFDLLLLADPSLEVVNSYIGRGHCFVAVRNGHI
                     IGVYVLIDTRPQTVELVNIAVSPQEQGKGIGKKLVFHAIETAQSMGYKTIEVGTGNSSI
                     SQLALYQKCGFRIVGIDKDYFINHYQDAIYENGIQCRDMIRLSKHLF"
     misc_feature    complement(13291..13303)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.6"
                     /tool="antismash"
     misc_feature    13611..13620
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 17.22"
                     /tool="antismash"
     misc_feature    13613..13626
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.97"
                     /tool="antismash"
     gene            13656..14099
                     /locus_tag="EG886_RS03655"
     CDS             13656..14099
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037405.4"
                     /locus_tag="EG886_RS03655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF559 domain-containing protein"
                     /protein_id="WP_124726869.1"
                     /transl_table=11
                     /translation="MAKFTVQLRRDWDYLKWIVMYVVQLVKTRRLPDWQRIKCSRSPIQ
                     IRLYDALKREGYKVLAEYETCGYQVDLVIKKYRLAIECDGMAYHSSEEQKKRDRKKTAV
                     LTKHGWKVMRFKGVEINRQLEKCVKRINEYTGIHEKKRWFFRK"
     gene            14324..14941
                     /locus_tag="EG886_RS03660"
     CDS             14324..14941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007786144.1"
                     /locus_tag="EG886_RS03660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YhbD family protein"
                     /protein_id="WP_124726870.1"
                     /transl_table=11
                     /translation="METDLISKKELLELTGISYGQLYRWKRKKLIPEEWFIRKSTFTGQ
                     ETFFPRDKVLARIEKIKNMKEDLSLDEIAELLSPLPIPRSVKRSEVAGLVSETTLRWFT
                     EKYGDPEEWEFGRVLSLYVLDRLVKTGEISLAEGETLYGLLGKTEGMGGEKGCELIFFR
                     KMGVSGFALIEAGQDIRFDDQVKIPVRLQLSQLSEELKIKLI"
     gene            14956..15684
                     /locus_tag="EG886_RS03665"
     CDS             14956..15684
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016408.4"
                     /locus_tag="EG886_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_124726871.1"
                     /transl_table=11
                     /translation="MDHNDLLISGSMSTAGGTFGQVKISGHATVKGDLQCNDFKVNGNA
                     DVSGGVRATDAVIRGNFMADGDFRASSLQLHGHADIKGDCHADRILLRGMTKIGKSLTG
                     EEMEIKGTVHVKENCEAEVFNIQGSFEIGGLLNAGKIDITLFGGAKVKEIGGETITVNR
                     ETITSKIARLIKSLFSFSMNHTLTADVIEGDDIRLEYTTASVVRGNHVKIGPGCEIGLV
                     EYKNSLDVSPEATVKERKKI"
     misc_feature    15781..15795
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.88"
                     /tool="antismash"
     gene            15816..16490
                     /locus_tag="EG886_RS03670"
     CDS             15816..16490
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124726872.1"
                     /transl_table=11
                     /translation="MNGRNKFFALLLTVTLIVPLTGCKWGKAGGFLGDFVERAVRREVG
                     DAILRKPTVEERAAFNYVRNLYQPWLSEQEKKEIMDMLLPDEPLKRTLNDHGPDPILEQ
                     LEREHWNEPSRSIGEVMITSRARENLKSPEKLRGVMIFAKSEIYVFFPPGTLKPGSDGR
                     QTALRKLTLVNLLDNSWRVVKDEVVLKHPENPMTFQQFLDSEDYENIFPVIQDWKRGET
                     LL"
     gene            16722..17264
                     /locus_tag="EG886_RS03675"
     CDS             16722..17264
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="EG886_RS03675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_124726873.1"
                     /transl_table=11
                     /translation="MQDEAVLVEKVLAGNREAFEPLVRKYAPRIYRVVLRMVHHSEDAR
                     DLTQEIFFQVYRKLSSYQPDRRFSTWLYQIAVNRCIDELRKRKGKRLVALNDEWVSNEP
                     GPEKVAIDRMRVDDILKSLDGMPENWKLIFLLRFVDDLSYSEIAEVLGISLNDVRNGLY
                     RTRQKLRMQFQAKEGAG"
     gene            17261..18085
                     /locus_tag="EG886_RS03680"
     CDS             17261..18085
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024881.4"
                     /locus_tag="EG886_RS03680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="WP_124726874.1"
                     /transl_table=11
                     /translation="MRSCVDDEVIMAFADGELSPQERNMVQDHLRNCPACEYRLHAFLE
                     ENQRYADWMKEPDLPDGWVEQIRGSVSGEDRKTFFGGRIRPKPVFRWISLASACALLLV
                     GGILWLSPSFTLFSGGDVSTAGIHRNIKRDRNMDQADWSVTDKGVTLRIIDLVVHPSEI
                     VATYEILKEGKRLDPRQYRDEEKRIDFVRAFLVHESGKILKENPWIGQKGEYGYVSFRD
                     LPVPLPELLFLEFTSDGFNGVPGNWSLRIPVYVSMADPGENGNVTDGTREGP"
     misc_feature    18168..18183
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.65"
                     /tool="antismash"
     gene            18419..18808
                     /locus_tag="EG886_RS03685"
     CDS             18419..18808
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS03685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124726875.1"
                     /transl_table=11
                     /translation="MAKMKIRPSQPYSPPEMPMQEMPMQMDVSMQAAHAAEAAMHSTQF
                     QKKHPSQPPSADELRKELKQLRELSEKVNRQLKRGQLEKTTLITLNEKLGYLKINYGNI
                     AAISVAAAGIISGLKDLIELIQMFD"
     misc_feature    complement(18423..18437)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.93"
                     /tool="antismash"
     gene            19047..19340
                     /locus_tag="EG886_RS03690"
     CDS             19047..19340
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EG886_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_124726876.1"
                     /transl_table=11
                     /translation="MSDNSSRSMEDIVNAMPEWVKMDVAIEIMAEVLSDQRRAIAEEEN
                     KELPDPEKLKRLKDEKRELLKERQAMYTGDKEVIHKILIKYGEKVREKYTGA"
     gene            19343..20335
                     /locus_tag="EG886_RS03695"
     CDS             19343..20335
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018154.4"
                     /locus_tag="EG886_RS03695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zeta toxin family protein"
                     /protein_id="WP_124726877.1"
                     /transl_table=11
                     /translation="MDPLAYKLSDEEHQEVFERLKNELFAFTTSVEKPTAVILGGQPGA
                     GKGGLIALSAREFPDSNFVVINGDEFRKEHPKSEEIFKKHEQDYAKLTDPDVREWTKKL
                     FDLAIQTKRNLIFEGTMRTDGPIRNTLRNLKQQGYHVVVRVMAVNEKISLLGTHERYEE
                     QKQIFGHGRSVPKEAHDAAYDGMLRTIERIEKEKLFDLLQVYNRDKTLLYENRVLGNEW
                     KHPPKVVEAIQKERNKEWTPEQVEQYIKAWNRVMDKMVLRNADPQEIIAVCRLCHEILA
                     NDLVRAQSKIAKLTKVIQLNQLLQKESPNKHQVSLNTNKMQNREDDVVR"
     misc_feature    20612..20627
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.38"
                     /tool="antismash"
     misc_feature    complement(20614..20627)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     strong, score: 26.74"
                     /tool="antismash"
     misc_feature    complement(21068..21081)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    complement(21856..21867)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.15"
                     /tool="antismash"
ORIGIN
        1 ccgccaagtt ccgctttttt cgccgggtgt gtcggccgaa cgggtccgtt cgaacttcag
       61 aacaggacca gttggttgtt ttcgggaagc ccctcgaggc atcccatctc tttcagaatc
      121 tccacgacgg tgctggagac gcgggtacgg ctctggaagt cttccacgga caggaattcg
      181 ccgtctttgc gcgcttccat gatgttcttg gccgcgtttt ccccgacgcc ggcgatggcg
      241 gcgaacggcg gaatgagtgc gtcgccgtcg atgacaaatt gcgtggcgtg agaacggtac
      301 agatccacgt tcttgaattt gagtcctctg gcatagaatt cgagcacgga ttccagtgtg
      361 gtgaagaggg ctttttcttt ggggggcgcg gtgttcccct tatcctggat ctctttcatc
      421 ttgcgtttga ccgcatccgg gcctttcagc accacgttca ggtcgaaatc atccaccaga
      481 cggtagaaat acgtggcgta atactgaatg ggccagtaca ccttgaacca ggcgatcctc
      541 accgccatca tcacgtaggc ggcggcgtga gcccgcggga acatgtattt gatcttgcgg
      601 caggattcga tgtaccattc gggcacgccg tgttggcgca tcagttcggc ctcttcttcg
      661 gacacgcctt tgcccttccg caccttctcc atgattttga aggattcttt cggcgggcaa
      721 cccttgtaaa tcaggtagag catgatatcg tcgcggcaac agatcgtgtc ggacagggta
      781 caggttccgc tgcgaatcag ctcctgggcg ttgcccagcc aaacgtccgt cccgtgagac
      841 aatcccgaga tccttaccag ttcggaaaac ttggtcggac gggtgtcctc cagcatctga
      901 cggacaaacg aggtgccgaa ctccggaatg ccgagggttc cggtttttac cccgttcatg
      961 tcttccggct tgatgccgag cggttcggtg ctgctgaaaa tgcccagcac tttcggatca
     1021 tccagcggaa tttcccgcgg attgactccc gtcagatcct gcagcatgcg gatcgatgtc
     1081 gggtcctgat gacccaggat gtccagcttc aaaatggttc cgctgatgga gtggtagtcg
     1141 aaatgggtgg tccggatgcc ggacttgatg tcgtcggccg gatgttgcac cggagtgatg
     1201 tcgtgcacgt ccatgtattg cggaacgacc atcaggccgc ccggatgctg accggtggtc
     1261 cgtttcaccc cggtgcagcc ttccaccagc cggtcgattt ccgcttgccg gagatgcaga
     1321 ttgtgttgtt cctggtattt cttcacgaaa ccgtaggcgg ttttttcctg caccttcgag
     1381 atggtgcccg cacggtagat gtattctttg ccgaacagtt cctccgtgta ggcgtgtgcc
     1441 cgtgcctgat aatcggaacc gaagttgaga tcgatgtcgg gagttttgtc cgcttcgaaa
     1501 ccgaggaacg tttcgaacgg aatgtcgtga ccgtctttga gcatttttgt gccgcatttc
     1561 ggacaatcct tgtccggcag gtcgaagccg gactccacgg aaccgtcgag gatgaactcg
     1621 ctgtgcttgc aagttttgca gcgccagtgg ggcggaagcg gattcacctc ggtgatgtcg
     1681 ctcatggtcg ccacgaacga agaacccacc gaaccgcgcg atccgaccag atacccgtcg
     1741 gacagcgatt ttgtcaccag gcgttgggag atcaggtaga tgacggcgaa tccgtgcttg
     1801 atgatgctgg tcagctcgcg atccagccgc ttctgcacgg tttcgggcag cgggtcgccg
     1861 taccattcac gcgctttttt gtagcacatc tccgaaagct cctggtcggc cccttcgatg
     1921 acgggtgtgt tggttccgtc gggcagcagc ttgatttctt cgatggcatc ggcgattcgg
     1981 cgcgggttgt ccacgaccac ttcccgggct ttctcttccc cgaggtaaga gaactcctcc
     2041 aacatctcgt tcgtggtccg aaaatgggct ttcggcagcg ggtcggtgtt ccggtagttg
     2101 ttttgttgct ggtgcaagat gtcccggaag atggcgtcgt gctcgtccaa atagtgaacg
     2161 ttggccgtgg ccacgaccgg tttgcccaac ttttcgccga tttccaccag caggcggttg
     2221 gcttcgcgca gccggttggg gctttccacc aagccttttt ccaccaggtg catgttcaga
     2281 tcgaccggct gaatctccag gtaatcgtag aattgcgcga tctcttccac ttccgtcggc
     2341 gatttgttga gcgccgcctc atacagttct ccccgttcgc aaccggaccc caccaggaga
     2401 ccttcccggt gcttcaccag ttcgctgcgc gggatccggg gaacgcggtg gaaatatttc
     2461 atgtgtgaca ggctgatcaa tttgtacagg tttttcagac cgacctggtt tttcaccagc
     2521 aaaacggcgt ggaacggacg aagtctcgac aggtcccgct ccccgatgct gtcgttcagc
     2581 ttgtgcaaat gggtgatgcc tttttcggtg gtatcgagga gcattttcca caggatctgt
     2641 cccgtggttt ccgcgtcgta aatggccctg tggtgctgct ccaggtggat gcccagcttg
     2701 tcggccagcg tgttcagccg gtaatttttc atgccggggt agaggaagcg ggccagctcc
     2761 agcgtgtcga ccaccggatt tttcacgggc tcccggccga tccgcttcac cgcctcctgg
     2821 aggaagccca tgtcgaaccg ggcgttgtgc gcggacaaca cgcaaccgtc gatgaatccg
     2881 agaaaccgtt cgatcacgtc atcgatttcc ggagcgtctt tgagcatgtc atcggtgatg
     2941 tgtgtcagtt caatgatgtg ctggctgagc ggccggtgag gattggcgaa ttcggagaac
     3001 cggtcgatga tttccccgcc tctgatcttg accgcggcca gctcgatgat gacgtcatga
     3061 acggcggaca gcccggtggt ctccacgtcg aacaccacat aggtggtgtc atcgagcaag
     3121 gggcgctcat cggcgttcat cacgatgggg acgccgtcat cgacgatgtt ggcttccatg
     3181 ccgaaaatca ctttgatgcc gtgctttttg ccggcggacc aagcatcggg gaaagcctgg
     3241 gccactccgt gatcggtgat ggcgatcgcc ggatgtcccc attttgccgc acgcttgatc
     3301 agttctccgg catcgtggat gccgtccatg gcggacatgg acgtgtgaag gtgaagttcc
     3361 acccgttttt ccggtgccgt gtcctgacgc tccacgggtt gggcttccat gaggtcgttg
     3421 accatcagaa ccagatcgcg ggtgaacgtg tcaaactgga cggagccccg gaccttgagc
     3481 caatcgccgt ttttgatttc tttcaggacc gccgcttgct ccttgtcgcg ggcaaacagc
     3541 ttgcaggaga tggagttggt gaaatccgtg agattgaacg tcaaaagcaa tcgtccgctc
     3601 ttcagctcct tcagctcgct tttgaacacc ttgcccttga cgatcacgct ccgctcctca
     3661 tcctgaatgt cacggatggg aacgggttcg ccttggatgt tgtatccgat ccgcttctcg
     3721 accggcttgt cgttttccgg cgcttcggcg gatttttccg aggcgcgtgc ctgctccgcc
     3781 agcgcctgct gcaccagttc ctgttcttcg cgctttttca cttcctggaa gcggtccagg
     3841 agcgccttgt catctccgtt ttccgcaagc agccgaacag gcagctccct gccggtgatc
     3901 ctggtgtaga accgggccac gtgccggtcc agttcccgtt gacgggccat gcccagaacc
     3961 gcggggttgt tgaacaggat ctcgatccga tcttggttca cccgccaccg ggcatgtccg
     4021 aaccaggtgg cggcagcggg agtgacatgt tcctgaatca gtttttgaat gaagtgcttg
     4081 tatttctgaa ggacgatttc atgctggatc cgctcgtaat tgaattggaa agagacctga
     4141 atgtcgggct gaaaatgtcc gcgaacccgc tggatgaact cttcccacac ttccggatcg
     4201 atcggctcgg gcatccatag ccggatctgc caggattttt ttcccggatt cacccggact
     4261 tcacggattt ccgcatcccg aaagtgagtg tccagccatt ccggcgggag gtgggtttcc
     4321 ctccacagcc gttccagtcc gttgcggtat tccgacacga cgaactcacc tccggcctga
     4381 tggattcgtt ccggcctgtc cgatacaaga aagaggcgtg gcaggaaagg gcacaggcct
     4441 gtatgcgtct atcatcctat catatcggga aggggcggac aatgagagcg gaagcggaga
     4501 atccaccgga atccgacggt ttttttcgcc cgtatcaagc aaaagcgcag cttgctccgt
     4561 ttttgggcaa actgcgcttt tcggcatgta cgaaatattc tgtctattca ccgcgcaatt
     4621 ccggcggctt gtcagtgtag agcacgatga gcttcatctt cttcacctcc ttcaatcagt
     4681 tggacatgga gccggaagaa tcgttccttg tacttttccg acgtcttggg atcatccttt
     4741 tcgcaacaac gggccagttt gacaaggatt ttttgctcct gctccttgag gcgatgtttt
     4801 tcggcgatcg agagcgcttg ccggtagcat tgcatcgcct tgtccgtctg gtcttgtctg
     4861 acgtgacaat ctcccagaaa aatcagagct tcgcaatgcc ggaagtcatt tcgggttttt
     4921 ttccccagtt ggaccgcttt ggccaggatt ttttccgcgt cgccggtctg accggtcttc
     4981 aggtacagca gacccagctt ggtgtgggtg gagacgagca gatgtttccg ggtgatcttt
     5041 ttctccaatt tgagtgccat gaggaaacaa cgctccgctt tggcaagatc cccgatcccc
     5101 aggcaagctt ctcccaacgt ggtccacagt tcgaacgacc ggtccacgtt tccgtacagg
     5161 cgggaccatt ccagggcctc catgcagatc ctcgcggcat tttcatacaa tccgtgcttg
     5221 atcatcaggc aagcccgaac ttcatacatg gtcaggtgga tgtcgggaac ccggatgctt
     5281 tcgaattcct gccacagttc gtccagataa ttgagagcct cctcgttgcg atccatcttc
     5341 tccagataga tgatttgacc gattttcagg tagtgaacga tgtggggcat gtccccgtcc
     5401 ggaagaaaac agtccagtcc cttttccaca tagaggagtg cctgttccaa attgttgaga
     5461 tagtagctgc atctggacag ttcgtaacag gccgccgcct tcagattgga agattccgct
     5521 tccgggatct gggggctcag gctgatcacc ttgtgcaggt gattttgtgc cttcagccat
     5581 tgccttttcc gggaatagca cagccctttg aggaaatagg tgtatgcctg cacccaaggt
     5641 tggtcggtct tggaggtcag ggaacggaga ctctcgagcg cctgatcggg tccgaccagg
     5701 tcgatgtcgt gctcgatggc gagcagcgtc aatttcgtgt ccgctttccg gcacttttcc
     5761 tcctgggcct ggcaggagag ttcggtcaga tccagccgga gcttccggca tatctctttc
     5821 aatacgatct cactgaccat ttctcctttt tctgccttgc gaattgtgtg aagtttgatc
     5881 acgtcgtcca ccaggtcgct ttgtctcagc cccagttctt tccgcttgct tttgatgact
     5941 ttccccgcat gttcgtaatc gagctggagc aaatcttcca cctcccgaaa aaaaagattt
     6001 gtggtttgat tttttcgttt ttggttcaaa ttcggtgcat gtatgcgagc atcggatgca
     6061 tttgtgcgcg agaaaaacgg gttctcctga cttttttgcc aacttttgcg gggattcctt
     6121 ccgtccgtat gcatttttgc gaatttgcat gcaaatgtcc gtgggactaa actatgacta
     6181 tgggaagaaa ttggaagagt ggaggtatca tagccaaccg agcgtttcag gagggaatga
     6241 agggtgctga aagttcaggt ggaaggcgag atgaggaaag tggaaccgtt tgtcagggag
     6301 ttggcccgtc gtcctcacgt ggaagtggca tccgaagagg tccgggtgat ccgggaaatg
     6361 gagccggaca tggtacgggt ccggttccgg ttgcagcatc agccgcaacg ccgtgtgaaa
     6421 gtggtgagcc tctttgacgg aaacggccgg gaaatccgga ttcccctcat ggatgtgatc
     6481 agcgtccgga tggatgacgg ccgccacatc gtgacaggtc gttcgtttga catctttgct
     6541 tgaaaggaaa ccgcgggaac aactttatca tgatggtcaa gggaggcgag cggatgctcg
     6601 tcgttttcct ttttcggaag agaatcgtgc gcccccgcca caaaagcgga gggcgcaccg
     6661 cctgttgccg gaatgtttga caacgaattt gtccgccgga catccggcgg ctgcccgaaa
     6721 tacggtcggg tcactgatca taccttctgt ttctgccttc cacgaggatg ggccttacaa
     6781 acgggcggat gcgctccatc aggcgtttgg ccttcagcgg ttcaaaaccg cccttgcccg
     6841 tatgggcgaa atgttcttcc agttcgtcca aactgagatt ggatgtgtag atggtgggca
     6901 aatgttcggt catccggtac tggaaaatga cggacaaaat gtcgtcgcgg atccacgggg
     6961 tcagtgtttc ggcaccgatg tcgtccagaa tcagcacggt cgtggttttg agcgcatcca
     7021 ccttgtcact gacgctgttt tcattgatgg cccccttcat ctcttccacc agggccggaa
     7081 gatgaaccat gacggaagcg atgccgatgc tcgccagttg attggtcacg gcgccggcga
     7141 tgtagctttt gcccactccg aacggtccgt acagatagag tcccttgtcc ggcagcccgt
     7201 tttcgaattc catgcaaaaa tcaatggccg cactgacggc ttcttcccgt ttggcactga
     7261 gttccaccga ttcgaaggtg gcgtttcgga tctccacggg aatgtggtgg gaacggatca
     7321 gggaacgccg gcgttcggat tctttgtgac tgcgcagttt ggagcattcg gtcagtttca
     7381 ggctgatcgc caagccgtat tgctccagca ccgggtagtg ccccggagcg gaattggggc
     7441 acttctccag gccggggcat tggcgacagc tcgttctttc cgtgacaaac tgggacagca
     7501 gaatcagcga acgccggtaa caatcaagcg gaagttccgg gtgccgctcc gcaaaccgcc
     7561 tcacgtccgg gtggcggaga agggtgcgga gcatcgcttc ggggtcgggc aaagggcgat
     7621 tttctctatg aaaaggaacc acaacgtctc cgagcttttt catgaataac tcctccggga
     7681 ggattttgtg ccgccctcgg gcggaaccat cttctattct atcaggaaga ggggccgcct
     7741 tcatccggaa gcacaatttt ttccaatcgc gttgactttg cacgaccgtt ttgagtaaaa
     7801 tgaatgctct tgaaaaaacg cgtgcaaagg ggagaccaag catggaagac gcgatacgaa
     7861 gcgagcgatc gcgccttcgg gaagtcctgg atttcatcga tcaacggata gagcaattgt
     7921 caaacatccc tgcctaccgg ggcaaggatc cggtggagat cgccctggac gaaaaacgcc
     7981 gacgtgaatg gggacaactg cgtcgcacgt cttcccagcc atatttcgga cggctggatt
     8041 ttcgggagga cgggtcggat cacgtgtccc ctctttatat cggaaagttc gggattcagg
     8101 gagaccggcc ggacgagctg ctggtcatcg attggcgggc tcccgtggcg agcctgttct
     8161 actcgttcgg cggccaggga gaccgggccg aatacctgtc gcccgacggt ccggtggagg
     8221 gaaccgtgta cttgaaacgg aacctggtca ttcgtcagcg ggagctggag cgggtggtgg
     8281 acacttgggt tcgtggcggg gacaatctgg gggcggccga cgagtttctg ctgtaccgcc
     8341 tgggggaaag caaggatcac cgccttcgcg acatcgtttc caccattcag tccgaacagg
     8401 accggatcat tcgtgcggag cgggacaagg ccttggtgat tcagggagtg ccgggcagcg
     8461 gaaagaccac cgtcgctctg cacagactgg cgtatctgct ctaccggtac accgggcaaa
     8521 tgcggccgga ccggatggtg atcttcgctc ccaaccgcat gtttctggaa tatatttcgg
     8581 acgttctgcc cgagctgggg gcgggagacg ttcggcaaac cacgtttgaa gaatgggcgc
     8641 tcgaacggtt ggaagaaaag gatcggattc cgtgggctcc ccatctttcg gcaccttggc
     8701 ggggaacgat cggatttctt cgggaattgg acgcgttcct cgaccggacg gaggaaatgt
     8761 tcgtgcccga catcccgttc gttccgtgga acggcgcgaa actttcccgg gaagacattc
     8821 accgcctcca tgatgaggaa taccgccatg agccgctcat gaaacgcaag gatcggattc
     8881 atgcccgcgt tcgccggtgg atggaagggc tgtacaaaga gatctccgac acagacccgc
     8941 gcggaatcat ccggaaggaa gcgcggaaac ggttttccgc ctgggcgcgg tcctggccgt
     9001 cccacacgcc gttgaagctg tatcgccgct ttctcaagga aacggaaaat gtccggcttc
     9061 gggaggcggg accggatgat ctcgcaccgc ttttgcgcat tcgacaaagg ctttacggag
     9121 tcgcgtcgga agagcggttt gaacacgtgg tggtggacga agcccaggat ttttcaccgg
     9181 cgcggttcga ggtcctcaaa gcgtacagtc ggatggcgtc attcaccatt ctcggggact
     9241 tgctgcaaaa catccggagc ggcagaggca tcgccgactg gaacgaagtg atcgatctgt
     9301 tcgacgaagg gaaggcgtcc tatcacgaac tcaatcgcag ctaccgctcg accatggaaa
     9361 tcatccggtt tgccgccgga atcatcgaac cgtaccgacg gggcatccgg cctccggttc
     9421 cggtgtttcg ctccggcgat cccgtcaggg tggtgaaggt gacaccggag aggagacggg
     9481 agacggtccg ggaggaaatc cggcgtctca ccgcaagcgg ctccaaaacg gtgctggttg
     9541 ccgtccggtc ggaagaagaa gctcttcgcc ttcatcagac gcttcgggag tacgggatcc
     9601 aggccggcct gctggaccaa acgcaggaag ggtacacggg cggaatttcc gtcagtaccg
     9661 tcgaccgggt gaaagggatg gagtttgatg ccgtggtgtt ggccgacgcg gatgcggccg
     9721 actggccgga tgacgaatct tcggcccggc ttctttatgt gggagtgacc cgggcgctgc
     9781 accggctggt gctggtcacc tccggagatt tgtctccgct ggtggaacgg gtggacccga
     9841 cgttgtatga gtcggtgaca gattgaacga gacaaagctt catcgcggga aacagcctga
     9901 atccacgtgc ccggaatgca cggggttcag gctgtttttg cgtcatgtcc gttgccgccc
     9961 ggccataacc tgttaaaaaa cggtgatgag gagacgggat atgcccgagg tgagccttga
    10021 tcaagtgaac aaagcgatcc accggctgac cggtgagctg gttcgccgtc agcgggagga
    10081 tggccgatgg agcttcggtt tcgtgaacgg accgatgacc gacagtcagt ttctcctcct
    10141 gacgaacgta cttggcatgg aggagaacga gatccggcaa gggattgcgg aaagactgct
    10201 ttcccttcag caaccggacg gaacctggaa acggttcccg gatgaacggg aaggcaaccc
    10261 gtcggcaacg ctggaagcct gtttggcgtt gttgtacgga ggataccgcg atccgtccga
    10321 ccggcgaatg aaaaaagcga gagagtttct gaaaacccgg gcggcgggca tcggctctct
    10381 ctcccgaacg ctgttgccgc tgttcggtca cggggactgg aagaatttca cccgtcttcc
    10441 ggttgaattt ttgctgttgc ccgcgcaaag tcctttgaac tttttcgatt tcgtcgggta
    10501 tgcccgcgtg catctggcac cggtcatggt gctcgccgac ctgaaacatt ccttccgatt
    10561 gaaagcgttc cgggaaattg atgactggct tccgccgctg ggaccgtctc tcatggatcc
    10621 ggtggagccg gaacatttca tgacccgcga cgaaatcgcc atcgccgtgt ccggggcggt
    10681 gtctgccaga cgccaactcc gccggctggc actggaacgg gcggaagcgt tcatgctgga
    10741 aagaacggaa gcggacggca cactcctcag ctatgccagc tccaccttcc tcatggtgtt
    10801 tgcgttgctt gcgctgggat attcccgcgg gcacccggtg attcgccggg ccgtccgcgg
    10861 gctcgcctcc tttgcccgtc ggacggaggg aggcatacac atccaggaag ccacatccac
    10921 cgtctgggat acggccctca cgctgtatgc ccttcaggaa gcgggatgtc cgccggacca
    10981 tccgtccgtg agacggggca tccggtattt gctgagccgt cagcacgatc ggccggggga
    11041 ctggatgctg cgaaatccgg gggtgcttcc gggcggatgg ggcttttccg acatcaatac
    11101 gatcaacccg gatgtcgacg acaccggtgc cgctctgcgg gcgctggcgc cggcggtgcg
    11161 gactggcaaa cacggggaag cgtggacacg cggcatcggg tggttgctgt ccatgcaaaa
    11221 ccgggacggc ggctggccgg cctttgaaaa aaacacgaac aaactgtggg tgaggctgtt
    11281 gccggcccgg gaggctcgcc aggcgttcac ggacccgtcc accgccgaca tcaccggtcg
    11341 ggtgatgcac ctgctgggaa gcgtcacggg ttggaccatc gatcaacctg aaatccggag
    11401 agcctggagc tggttgtatc accatcagaa atcggacggt tcctggtacg gacgttgggg
    11461 agtgcagtac atctacggaa cctgggccgc tctcaccgga atggccgccg ttcgcgtacc
    11521 gcgcaatcat tccgccgtcc gcaaggggat ccgttggttg ctgtccgttc aaaatcccga
    11581 cgggggatgg ggagaatcct gtcacgcgga tgaaaagagg aaatacgttc cgctgggcat
    11641 gtccactccg gtccagaccg cttgggctct ggacgctctc atcgcctggc atgacacccc
    11701 cacgccggag atggaaaagg gcatccgctg cttgctcgga atgttggaga agcgggatga
    11761 ttcctgggca tatccggtcg gggcgggact ggccggacag ttcaacgtgg tgtatgagag
    11821 ttatccgtat gtatggccgc tggtcacgtt ggctcattat cggaggaaat acgggaggtt
    11881 gtatgagaaa ccgttgattc catgaagaac attgttctgt tgccgccggc acttttcccg
    11941 ctccgttccg ttgctgacgc aaagtcactt gcgggaaaag cgccggctgt tgcatggaag
    12001 tgaagtgtcc tgtctatggt atacacgttg aaccgctggc cgtttttcct gcttcgttcc
    12061 gttgctgacg caaagtcact ccgcaggaaa aacgccggct tctgcgtgga agtgaagtgt
    12121 actgtctatg gtgtacacgt tgaaccgccg ggtgctgatc ccgcttcgtt ccgctgctta
    12181 cgcaaagtca ctcgcgggaa agcccgcggc agtgtggtgg accggatcgg cggattcaac
    12241 cgctatgaag tggcgatcaa cgtcgccaaa tatgcaccgt tcgccaggat ccgagggtgc
    12301 atgtgtttgc caaaggcacc gacttcccgg atgtgctgtc cggcggacct ctggcggcaa
    12361 gatatcatgc accgattctg ctgactccgc ccgaccggat ggattcgggg gtccaatctt
    12421 acctgaacca tacccaagag aaggacttct actacatctt gggcggtacg ggctccatct
    12481 ccacggaagt ggaaaaacaa ctggatgcga cgattcaata atatcggcgg atgcgatgat
    12541 tcccgttcgc cgggaacatc gctccatcat aagtgtttgt catcaagcgg acagagcggg
    12601 aaaaccgctc tgtttttcgt ttgcatcggt caatggggca acatcgttcg tgaccatcgg
    12661 cccatacacg caaatcgtgt caggtaaaga ggagggcgca acggtaggcg cgggacgcga
    12721 agggggggtt acgtgtgagg gggtcagaca cgtgaacatt tgtccttcat cagaaaagat
    12781 gctttgagag acggatcata tctcggcact gaattccatt ttcataaatc gcatcttggt
    12841 aatgattgat gaaatagtct ttatctatac ctacaatacg gaagccacat ttctgataga
    12901 gggccaattg agaaatactt gaatttccag tcccgacttc tatcgtttta tatcccatcg
    12961 attgagctgt ttcaatagca tggaaaacta acttttttcc aatccccttt ccttgctcct
    13021 gcggtgaaac agcaatgttc acgagctcca cggtttgagg tcgagtgtct atcaacacat
    13081 atactccgat gatatgtccg tttcttactg cgacgaaaca atgccctcga ccaatatagc
    13141 tgtttacaac ttccaaagaa ggatcagcaa gtaagagcaa atcaaaagga ggcttttcat
    13201 cgttgtgcaa agggcgaatt atcattacct ttcccatccc cgacttcatt ttttgggtac
    13261 tcccagccta tataactctt actgctatat tggcaaaacg catcggccgt tcgtttcgat
    13321 gaatgagcgg tcaggaaccg cggattcatg ccggcccatg attctaagct catctgatct
    13381 cctgcgtacg gggttcagac tttctctttc ccattatgtc gtataccaag tatatcaggc
    13441 cgtggagaaa aaggcatgcc gtgttgttcc tggcgtttgc ccaagctttc gccaagagct
    13501 gcatggatcc aatgtcgaga agggagggca tttgtgatgc aagagaaatt gctcaccact
    13561 tggatgtgat cagaacaaaa aatacacttg aagatgcgaa tgaattttgc taatttttta
    13621 aatgaatact tccagtattt gaaagggagg ccggcatggc gaaattcacc gtgcagctca
    13681 ggcgggattg ggattatctc aagtggatcg tgatgtatgt ggtgcagctg gtgaaaacca
    13741 ggcgtcttcc tgactggcag cggatcaaat gcagccgcag tcccatccaa attcggcttt
    13801 acgatgcact gaaacgtgaa ggctacaagg tgttggccga atacgagacg tgcggctatc
    13861 aggtggatct cgtcatcaag aagtaccggt tggccatcga atgtgacggc atggcttatc
    13921 actcctccga ggagcagaag aaaagggacc ggaaaaagac ggccgttctg acgaagcacg
    13981 ggtggaaagt gatgagattc aagggagtgg agatcaacag acagctcgag aaatgtgtga
    14041 aaagaatcaa tgaatacacg gggattcacg aaaaaaagcg gtggtttttc cggaaatgag
    14101 gaatggacga aatccctatg ccgaaccgac cggcccggat gagcgggtcg gtttgttttt
    14161 tggagcggaa tgccgccgta acggcagaga gcgggggcgc atccggcggg gacatcggcg
    14221 aaatttcggc gtcaaagatt ttttctttct taacgtaaca gtgttatgtt acaatgggtg
    14281 cagagggatg tatttggtgc aaaccgagga ggaggtgtca tcggtggaaa ccgacctcat
    14341 ttccaagaag gaactgttgg agctgaccgg gatttcctac gggcagcttt atcggtggaa
    14401 acgcaagaaa ctgattcccg aggaatggtt tattcgcaag tcgacgttca cggggcagga
    14461 aaccttcttt cccagggata aggtgttggc ccgcatcgaa aagatcaaga acatgaagga
    14521 agatctttcg ttggatgaga tcgcggaact gctttcccct ctgccgatcc cccgcagcgt
    14581 caaacgatcc gaggtggcgg gattggtgtc ggaaacgacg ctccggtggt tcactgagaa
    14641 gtacggggat cccgaagaat gggaattcgg ccgggtgctc tccctgtatg tgttggaccg
    14701 gttggtgaaa accggggaga tcagtctggc ggaaggcgaa acgttgtacg gactcctcgg
    14761 gaagacggaa gggatgggcg gcgagaaggg atgcgagctg atcttcttcc gcaagatggg
    14821 ggtttccgga tttgctctga tcgaggcggg gcaggacatc cgctttgatg accaggtcaa
    14881 gattccggtt cgtcttcaac tttcccagct ctcggaagaa ctgaaaatca aactgatttg
    14941 acggaggggg atttcatgga tcacaacgat ctgttgattt ccggatcaat gagcaccgcc
    15001 ggagggacat tcggacaagt gaaaatctcc ggacatgcaa cggtcaaagg ggatttgcaa
    15061 tgcaatgact tcaaggtgaa cggaaatgcc gatgtgagcg gcggggtgcg tgccaccgat
    15121 gccgtcattc ggggaaactt catggcggac ggtgattttc gggcatccag tctgcagttg
    15181 cacggtcatg cagacatcaa gggggactgt catgcggacc ggattttgct cagaggcatg
    15241 accaagatcg gcaagagtct caccggggaa gaaatggaga tcaaagggac tgtccacgtc
    15301 aaggaaaact gcgaagcgga agtgttcaac attcaagggt cctttgaaat cggggggctc
    15361 ctcaatgccg gaaagatcga catcaccctt ttcgggggag ccaaggtcaa ggaaatcggc
    15421 ggagaaacca tcacggtgaa tcgagagacg atcacgagca aaatcgcccg tttgattaaa
    15481 tctctgtttt ccttttccat gaaccacacg ctcaccgccg acgtgatcga aggggatgac
    15541 attcgcctcg aatacaccac ggcttccgtg gtgcgcggca atcatgtgaa gatcggaccc
    15601 gggtgtgaga tcgggctcgt ggagtacaag aacagcctgg atgtatcccc ggaagccacg
    15661 gtgaaggaac ggaagaaaat ctgaagaggt tcggaaggga tttccaaagc cggatattcc
    15721 ggcttttttt ctttttttcg gaaactgttc acgagcggga agttttccga agagttatca
    15781 tcttttcaga aaaatcatcg cacccggagg accagatgaa cggaagaaac aagttttttg
    15841 cgctgctgtt gacggtgacg ctgatcgttc cgttgaccgg ctgcaaatgg ggaaaagcgg
    15901 gcggttttct cggggatttc gtggaaaggg ccgtccgccg cgaagtcggt gacgcaatat
    15961 taagaaagcc cacggtggag gagcgtgcgg cattcaacta tgtccggaac ttgtatcaac
    16021 cttggctctc tgagcaagag aaaaaagaaa tcatggacat gcttttgccg gatgaaccat
    16081 tgaagaggac gctgaacgac catggacccg atcccatcct ggagcagctg gaacgcgaac
    16141 attggaatga accgtcccgg tccatcggtg aagtcatgat cacttcgcga gcacgggaaa
    16201 atttgaagtc tccggaaaaa ttgcggggag tcatgatctt cgccaaaagc gagatttacg
    16261 tcttttttcc gcccggtacg ctgaaaccgg gatcggacgg acgtcaaacc gctttgcgca
    16321 aattgacgtt ggtcaatctg ttggacaact cgtggcgcgt cgtgaaggat gaagtggtgc
    16381 tgaaacatcc cgaaaacccc atgacgttcc aacagttcct cgactccgag gattatgaaa
    16441 acatcttccc cgtgattcaa gactggaaac ggggagaaac gttgttgtaa gatccgcttt
    16501 cccgtcacgg gaaagcggaa tccgtttcat tttccgttcc tcaccgcccc cttttcttgt
    16561 cgatcagcga aatttcctgc ttacttcacg aagatcccgg tactttgtcc tgaaaaattt
    16621 tcgatgttgg ttgtgttttt tggcaaacgg gaacataaaa gtcgtggtgg gaacggatga
    16681 aatagtgagg gaacagaaag acagaacagg gagggagcgg gatgcaggac gaagcggtgt
    16741 tggtggagaa agtcctcgca gggaatcggg aagcctttga acccctggtc cggaaatatg
    16801 cgccacggat ctatcgggtg gtgttgcgca tggttcatca ttcggaggat gcccgtgacc
    16861 tgacacaaga aatctttttt caggtataca gaaagttgtc ctcttaccaa ccggatcgac
    16921 gcttctccac ctggctgtac cagatcgccg tcaaccgctg catcgatgaa ctgagaaaga
    16981 gaaaagggaa gcggttggtg gcactgaacg atgaatgggt gagcaatgaa ccggggccgg
    17041 agaaggtggc cattgatcgg atgagagtcg atgatatact gaagagtttg gacgggatgc
    17101 cggagaattg gaagctcatt tttcttctac ggttcgtcga tgatctgagt tattcggaaa
    17161 tcgccgaggt gctggggatc agcttgaatg atgttcggaa cggtctgtat cgcaccaggc
    17221 agaagttgag aatgcaattt caggcaaagg agggagccgg atgagaagct gtgtggacga
    17281 cgaagtcatc atggctttcg cggacgggga actttcaccg caagaacgga acatggttca
    17341 ggatcacttg cggaattgcc ccgcatgcga atatcgcctg catgcatttc tggaggaaaa
    17401 tcaaaggtac gccgattgga tgaaagaacc ggacttgccg gacggatggg tggaacaaat
    17461 caggggaagc gtcagcggtg aagaccggaa aacgtttttc ggaggccgga tccgcccaaa
    17521 gcccgtcttc cgttggatca gtctggcttc cgcgtgcgca ctgcttcttg tcggcggaat
    17581 tctttggctg tccccttcgt tcacgctgtt ttccggaggc gatgtgtcca cggccgggat
    17641 tcacaggaac atcaagaggg accgaaacat ggatcaagcg gactggagtg tcacggacaa
    17701 gggcgtgacg cttcgtatca tcgatctggt ggttcatccg agcgaaatcg tggccacata
    17761 cgagatcctg aaggaaggaa agaggctgga tcccaggcaa tatcgggacg aagaaaagcg
    17821 gatcgatttt gtccgggcgt ttctggtgca cgaaagcgga aagattttga aggaaaatcc
    17881 ttggatcgga caaaagggag agtacggtta tgtttctttt cgggatctgc ctgtcccgct
    17941 gcccgaactg ctctttttgg aattcacatc cgacgggttc aacggggtcc cgggcaattg
    18001 gagtctgaga atccccgttt acgtgagcat ggcggacccg ggtgaaaacg ggaacgtcac
    18061 ggatgggact cgggagggac catgaatgaa ggcgggctgc ctcaggtgaa aacagcatgg
    18121 atgatgagaa cacatctaca tatattcgtg ttttgatata taatgagaat ggaaatcttc
    18181 atcctgagga gacagcccca tggaagtatt aacagtcaat gcacagcaag cggaaatcat
    18241 ctcaagtggt ttggaagaat tgataaatgc cgtgaaagaa gcagcggagc ttgaaacgtt
    18301 cctggaaaag tttgatgata tggatttgag tgatttcagt tttcgtcgga tggaaccccc
    18361 ggtaaatcct cagccggtgt ttgcacggag gagctttgta tcttccggtg gtgccaggat
    18421 ggcgaaaatg aaaatcaggc cgtctcaacc atattctccg ccggaaatgc ccatgcaaga
    18481 aatgcccatg caaatggatg tgtccatgca agccgcacat gccgcggaag cggccatgca
    18541 ctcaacgcaa ttccaaaaga agcatccgtc tcaacctccg tccgcggacg agcttcgaaa
    18601 agagctcaag caacttcgtg aactttcgga aaaggtcaac cgtcagctga agcgggggca
    18661 attggaaaaa accacgctga tcaccttgaa tgagaagttg ggttatttga aaatcaatta
    18721 tggaaacatc gccgccattt ccgtggcggc ggccgggatc atcagcgggt tgaaggactt
    18781 gatcgaattg attcagatgt tcgattgagc tccgtcaacc gccgtgtgaa gcgggacctt
    18841 gcaaggttcc gtttttttgt ttcatgcttt ccccatggcc ccggtgcact ctgcttcgca
    18901 tgaggaggat gcggataatg gtcaattgaa aaaacataga ggaaaaattt ataatatgat
    18961 cgggataatc agcgaagatc tggaaaagtg ttcgatgaaa aacggtgact gatttaaaaa
    19021 ttcatcatct gaggaggatg ctttccttgt ctgacaattc atcgagaagc atggaagata
    19081 tcgtgaacgc catgccggag tgggtgaaaa tggatgtcgc cattgaaatc atggcggaag
    19141 tgctctcgga tcaaagacgg gccatagcgg aagaagagaa caaagaactt ccggatccgg
    19201 aaaagctgaa acgattgaaa gacgagaaaa gggagcttct caaagaacgg caagccatgt
    19261 acacgggcga caaggaagtg attcacaaga tcctcatcaa atacggggaa aaagtcagag
    19321 agaaatatac gggggcatag ggatggatcc gctcgcatac aagttgtccg atgaagagca
    19381 ccaagaggtc ttcgaacgcc tgaaaaatga attgtttgcg tttaccactt cggtggagaa
    19441 accgacggcc gtcattttgg gaggacagcc cggggcggga aaagggggct tgattgctct
    19501 ttcggcacgt gagtttccgg attccaactt cgtggtgatc aacggagatg aatttcgcaa
    19561 agaacatccg aagagtgaag aaatcttcaa gaagcatgaa caggattacg cgaagctgac
    19621 ggatccggac gtccgggagt ggaccaaaaa attgttcgac cttgcgattc aaacgaaaag
    19681 aaacctgatt ttcgaaggca ccatgcgaac ggacggcccg atccgaaaca cgctccggaa
    19741 cctgaaacag caaggctacc acgtggtggt ccgggtcatg gccgtgaatg aaaaaatcag
    19801 cctcttgggc acccatgaaa ggtatgaaga gcaaaaacaa atcttcggcc atggaagatc
    19861 cgtgccgaaa gaagcccatg atgcagctta tgacggcatg cttcgaacca ttgaacgcat
    19921 cgagaaagaa aagctgtttg atttgcttca ggtctacaac cgggacaaaa cccttcttta
    19981 cgaaaatcgg gtcctcggga atgaatggaa acatcctccc aaagtcgttg aggcgatcca
    20041 aaaagaacgg aacaaagaat ggacccctga acaagtcgaa caatacatca aagcatggaa
    20101 ccgagtgatg gacaaaatgg ttctcagaaa cgcggatccg caggaaatca ttgcggtctg
    20161 tcggctctgc catgagattc ttgccaacga tcttgtgcgt gcgcaaagca agattgcgaa
    20221 gttgacgaaa gtcattcagc tcaatcaact gctccaaaag gaatcgccga acaagcatca
    20281 ggtttctttg aatacgaaca aaatgcaaaa cagggaagat gatgtggtgc gatgacctga
    20341 gtctgccgcg ctggacccga ccaggcgacg gcaaggcgcg gcaactaaat ccgggtgttt
    20401 cctagggggg taaaatcaag aatcatagtt gtgttcacgg tggtttgaaa gagagggcat
    20461 gacatgaaga atagtgatgg taaatccgtt tgagttgcat ccatggtgga acatctcgtg
    20521 gcacaacaag agccggcagg gagcttttcc catgccggca ctgttctttt aggcggagct
    20581 attccattga tcaatgacac gatccgtaat gaataataat aattatatca catgaaacca
    20641 tgcaataaag catcaattga tttgataata ttgggatgat tccacatttc aatcggggtc
    20701 agtatgaaag agaaagtctt atgaagaagt ggaggaccaa ctcggaatga cccagcaaaa
    20761 aggcatcttt gaggagatca aacgagaaaa caaagcctat cctgatcagc aagttgtgct
    20821 gccgctcagc ccgagtgatt atcttgaatc gctgattcat catacggctc gtcaattaga
    20881 acaccggttt cggaaactga ttcgtgaagc gaaacatgtg caaatgctgg atctcgttca
    20941 aaagatcggt gaattagtag agaaagatgc tcatgaaaaa ctaagcttac cactttcgaa
    21001 gattatgtac cgatttgatc aacaggaatt tccagtgatc tatgatcaat cactgacgaa
    21061 actgcagttg atcgccaacg agtcgcagac aatgaacaat ttctttaaat ccttgaagtt
    21121 tgagatgctc acttcagatt cagtggattt tatggttagt tttgtgcgaa agtctggggt
    21181 tcagcttttg attcgtccgc ttcaagaatt agaacgcctt ggcaagcgcg ttcgagtttt
    21241 gacttcgacg tacatgaata ttacggagcc cgaggctttg aagaaattgc tcggcttttc
    21301 aaatgttgaa gtgagggttt atcaaacaga gggtgaatcg ttccatacga aagcctacct
    21361 cttccaccga gattctggac tgaactccgt aatcattggt tcatccaact tgtcgcattc
    21421 tgcgttacgc aatgggtatg agtggaatgt gaaaataccg agtgcaggtt atttgcccat
    21481 ctatgatcag gccaagcaaa agtttcaaca aacatgggaa gaccgcaagg ccatcgccat
    21541 cgacgaggcg tggttgaatc aatatcagat ggtctttcag caagcgaaga tgaagaagaa
    21601 agagagtgaa gtcctgttac agccgaaacc catatatctc actgatcggt catctccacc
    21661 cgttcaaccg aatgggatgc aagaacaagc gttgaaagca ttgaagcaaa gccgatggaa
    21721 tggccacaaa aaagggatga ttatcgcagc cacgggtacg gggaagacct atttgtcagc
    21781 attcgatgtg tttgatgtga agccgaagcg cttgttgttt attgctcatc gtgaagagtt
    21841 gttagatcga gcgatggaaa cattttcaca tgtatttgga cgggacgatc tctttggaaa
    21901 actaa
//
