LOCUS       NZ_CP033967            28889 bp    DNA     circular CON 04-APR-2024
DEFINITION  Bacillus velezensis strain 1B-23 chromosome, complete genome.
ACCESSION   NZ_CP033967
VERSION     NZ_CP033967.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 4141063)
  AUTHORS   Zhao,N., Piccoli,D.A., Weselowski,B.J. and Yuan,Z.-C.
  TITLE     Bacillus velezensis 1B-23 complete genome sequence
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4141063)
  AUTHORS   Zhao,N., Piccoli,D.A., Weselowski,B.J. and Yuan,Z.-C.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2018) Science and Technology, Agriculture and
            Agri-Food Canada, 1391 Sandford Street, London, Ontario N5V 4T3,
            Canada
  REMARK    Annotation added by database at the request of the submitter
REFERENCE   3  (bases 1 to 4141063)
  AUTHORS   Zhao,N., Piccoli,D.A., Weselowski,B.J. and Yuan,Z.-C.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-NOV-2018) Science and Technology, Agriculture and
            Agri-Food Canada, 1391 Sandford Street, London, Ontario N5V 4T3,
            Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. NOV-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.3x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003854915.1-RS_2024_04_04
            Annotation Date                   :: 04/04/2024 03:40:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,154
            CDSs (total)                      :: 4,035
            Genes (coding)                    :: 3,945
            CDSs (with protein)               :: 3,945
            Genes (RNA)                       :: 119
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 90
            CDSs (without protein)            :: 90
            Pseudo Genes (ambiguous residues) :: 0 of 90
            Pseudo Genes (frameshifted)       :: 46 of 90
            Pseudo Genes (incomplete)         :: 53 of 90
            Pseudo Genes (internal stop)      :: 14 of 90
            Pseudo Genes (multiple problems)  :: 20 of 90
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:25:02
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3531117
            Orig. end                         :: 3560006
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033967.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Agriculture and Agri-Food
            Canada 1391 Sandford St, London, ON N5V 4T3 Ze-Chun Yuan.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28889
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="11"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..28889
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28889
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18889](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18889)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(38..49)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     CDS             complement(257..358)
                     /gene="allorf_3531374_3531475"
                     /locus_tag="allorf_3531374_3531475"
                     /protein_id="allorf_3531374_3531475"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSYVCHLEVNRRSQKAARLEAAFYYRQSCRRWR"
     CDS_motif       complement(293..358)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSYVCHLEVNRRSQKAARLEAA"
                     /locus_tag="allorf_3531374_3531475_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(257..292)
                     /prepeptide="core"
                     /locus_tag="allorf_3531374_3531475_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1602.8"
                     /monoisotopic_mass="1601.8"
                     /core_sequence="FYYRQSCRRWR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSYVCHLEVNRRSQKAARLEAA"
                     /leader_location="[292:358](-)"
     gene            complement(360..872)
                     /locus_tag="EG882_RS17800"
                     /old_locus_tag="EG882_17800"
     CDS             complement(360..872)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154857.1"
                     /locus_tag="EG882_RS17800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17800"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_007407279.1"
                     /transl_table=11
                     /translation="MEDLLFEYKRTLKETKKWYKQLEEADETVLTSEELKDKKIIRTII
                     TDVEYVIEWLEKGRQPGIRRAIDRRDAYQRMLIKDPRIIETYSQALMFEPSGNVTEEDR
                     IRLRDALAVLTDREKEMLLLHKAECFSYERIAALLNVKKSTVQTTVKRALLKIQKQQEQ
                     RNQSPAS"
     gene            complement(986..1189)
                     /locus_tag="EG882_RS17805"
                     /old_locus_tag="EG882_17805"
     CDS             complement(986..1189)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936455.1"
                     /locus_tag="EG882_RS17805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17805"
                     /product="XtrA/YqaO family protein"
                     /protein_id="WP_032871270.1"
                     /transl_table=11
                     /translation="MNPKKLTDIEHTTLQSQLEEGKVRVIIIDGLKKEAWLAEAPEHGK
                     TLVETRKGDLARVEYEIGFKLN"
     gene            complement(1179..1520)
                     /locus_tag="EG882_RS17810"
                     /old_locus_tag="EG882_17810"
     CDS             complement(1179..1520)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015239676.1"
                     /locus_tag="EG882_RS17810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17810"
                     /product="hypothetical protein"
                     /protein_id="WP_043021268.1"
                     /transl_table=11
                     /translation="MQEKHSPAPWRAVHSGEEKTIYIYSAYSEADKEKFPYSNGRLIAA
                     VFNLSSYSQQINAALMAKAPELFEAAETALRLLRGESSEEKEAFINELGSLIHEVNILK
                     KTEDVKHES"
     gene            complement(1618..1785)
                     /locus_tag="EG882_RS21110"
     CDS             complement(1618..1785)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154863.1"
                     /locus_tag="EG882_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_003154863.1"
                     /transl_table=11
                     /translation="MCKLCGPKKVIVTETGFGAVFHPCPNCKTGTDLTPVIKRLERMVQ
                     DAKARLDARV"
     CDS_motif       complement(1729..1785)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MCKLCGPKKVIVTETGFGA"
                     /locus_tag="EG882_RS21110_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(1618..1728)
                     /prepeptide="core"
                     /locus_tag="EG882_RS21110_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.30"
                     /molecular_weight="4025.7"
                     /monoisotopic_mass="4023.2"
                     /core_sequence="VFHPCPNCKTGTDLTPVIKRLERMVQDAKARLDARV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MCKLCGPKKVIVTETGFGA"
                     /leader_location="[1728:1785](-)"
                     /alternative_weights="4043.7"
     gene            complement(1785..2585)
                     /locus_tag="EG882_RS17815"
                     /old_locus_tag="EG882_17815"
     CDS             complement(1785..2585)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007407283.1"
                     /locus_tag="EG882_RS17815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17815"
                     /product="ATP-binding protein"
                     /protein_id="WP_069007422.1"
                     /transl_table=11
                     /translation="MTKRTIEQILADLKNGKRPLLADRPEESDESRFDCPLCKDQGGYL
                     KNQLGMDVWVKCRCAAERKAERILSASEITGAFRKLDFKGFITRGKPQAVVDAYECALE
                     YVENFDKIKNCRKNSIALLGRPGSGKTHLLTALSNYVMRQKQTPVLYFPFVEGFTDLKN
                     DFDLLDAKLGRMKQADVLFIDDLFKPLNGKPRATDWQIEQMYAVVNYRYLNHKPVFISS
                     ELACDGLVQVDEALGTRIYEMCSDYLVIINGNSFDVNHRLEGAR"
     gene            complement(2485..3312)
                     /locus_tag="EG882_RS17820"
                     /old_locus_tag="EG882_17820"
     CDS             complement(2485..3312)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417603.1"
                     /locus_tag="EG882_RS17820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17820"
                     /product="hypothetical protein"
                     /protein_id="WP_025284603.1"
                     /transl_table=11
                     /translation="MNRKSYPFFIYSGLLNSEHYDKIGSAIWLFLWFISSTTKEHVKDG
                     VKWGIVLGHKPVKAREMADVFAVSEKTVRRWLEVLEQHEYIKTVRAPYGLIVSVKHSKR
                     FTPKKTLTRPEATDRTISADHRDKNVRREIDITKNHTAEETINDIAAHFIRLRSAQEGR
                     SVYPSPRDYQAIARIVSLGASAQEAIKWLGECFTAFEQRRTSSAETIKAFSYCAKYMED
                     RLNARIAGRTITTKKERNTIHDKTNDRADTGRPEKRKTSITGGQTGRIRRKPL"
     gene            complement(3302..3481)
                     /locus_tag="EG882_RS17825"
                     /old_locus_tag="EG882_17825"
     CDS             complement(3302..3481)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154869.1"
                     /locus_tag="EG882_RS17825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17825"
                     /product="hypothetical protein"
                     /protein_id="WP_007407285.1"
                     /transl_table=11
                     /translation="MQPIIIRFSSNPADQRCLGKAGGSISFTACGLPVFRFDNRLQYER
                     YIGLKTNGDVPYES"
     gene            3672..4010
                     /gene="xre"
                     /locus_tag="EG882_RS17830"
                     /old_locus_tag="EG882_17830"
     CDS             3672..4010
                     /codon_start=1
                     /gene="xre"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389133.1"
                     /locus_tag="EG882_RS17830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17830"
                     /product="HTH-type transcriptional regulator Xre"
                     /protein_id="WP_003154871.1"
                     /transl_table=11
                     /translation="MIGGRLKSLRGKKTQEEVANHIGVSRARYSHYENGRSEPDYDTLQ
                     KLADYFKVSTDYLLTGKEPSDEDMFADPDLQIAYRDMQDFSPESKQQAIEFINYLKEKE
                     KNRRPKHK"
     misc_feature    4067..4080
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.38"
                     /tool="antismash"
     misc_feature    4131..4144
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.52"
                     /tool="antismash"
     gene            4160..4750
                     /locus_tag="EG882_RS17835"
                     /old_locus_tag="EG882_17835"
     CDS             4160..4750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016936463.1"
                     /locus_tag="EG882_RS17835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17835"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_007610775.1"
                     /transl_table=11
                     /translation="MGDFLTHLEEYVKNLYCRMGMTAPLHIDMQMIAKELDIWIHFEDT
                     HSMMLKRDGMYSIVLNQKKSPEEQWQDFAHELCHVLKHTGNHFHMNKLFRELQEFQANH
                     FMYHFCVPTFMLLNMELPQRRSHAVILIAAAFRVTASFAEKRLELFERRKAGIQFQKRL
                     ACLLSDKRPNVYYESGQTHLHAAEEKTPYFIEN"
     gene            complement(4889..5494)
                     /locus_tag="EG882_RS17840"
                     /old_locus_tag="EG882_17840"
     CDS             complement(4889..5494)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014417516.1"
                     /locus_tag="EG882_RS17840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17840"
                     /product="poly-gamma-glutamate hydrolase family protein"
                     /protein_id="WP_043021270.1"
                     /transl_table=11
                     /translation="MKDRYDNFAALSAAESEYRIIYEEKEGSKCIVLAPHGGRVEPGVS
                     ELVRAFSDQSSIYLFEGTKRCDNRSLHLTSTRFDEPLALEKVTAHHYALAFHGYHDLKK
                     ANTLVGGADLEKARLICDLLREAGFDAELTEKNDRLAGVNPGNIVNRTKRKMGLQLEVS
                     TAQRHALFSNFGCRGEKYTPTDLFFRYVEAVKAGFYDK"
     gene            5603..5980
                     /locus_tag="EG882_RS17845"
                     /old_locus_tag="EG882_17845"
     CDS             5603..5980
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389129.1"
                     /locus_tag="EG882_RS17845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17845"
                     /product="PH domain-containing protein"
                     /protein_id="WP_007610770.1"
                     /transl_table=11
                     /translation="MGFINGLLGNASTISTAEAKAELARILLEGENVNAAFKLVRDIIV
                     FTDKRLILVDKQGLTGKKTEIQSIPYKSISRFSVETAGRFDLDSELKIWISGAELPAVS
                     KQFKKDESIYDIQKALAAVCM"
     gene            complement(6018..6971)
                     /locus_tag="EG882_RS17850"
                     /old_locus_tag="EG882_17850"
     CDS             complement(6018..6971)
                     /EC_number="3.5.1.28"
                     /GO_function="GO:0008745 - N-acetylmuramoyl-L-alanine
                     amidase activity [Evidence IEA]"
                     /GO_process="GO:0009253 - peptidoglycan catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="16.5 : Explore"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389128.1"
                     /locus_tag="EG882_RS17850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17850"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_015417280.1"
                     /transl_table=11
                     /translation="MGIEVKKRLVSADKYALKCPNPMTPEYITIHNTANDASAANEISY
                     MTGNSESTSYHFAVDDKEVIQGIPLDRNAWHSGDGTNGTGNRKSIAIEICYSKSGGERY
                     RAAEELAIAFAAQLLKERGWGIDRIRKHQDWNGKYCPHRILSEGRWDEVKAKIEKKLSG
                     SMPAKKASIASSASEYHVKKGDTLSEIAASHGVSVKSLQSINHITDPNHITVGQVIKLA
                     QTGSSSKSQAVSSYPLPSGVIKVTKPLTKGTNVKQVQNALSALYFYPDKGAKNHGADGV
                     YGPKTANAVKRFQSVSGLTADGIYGPKTKAKIEEKL"
     CDS             complement(6999..7076)
                     /gene="allorf_3538116_3538193"
                     /locus_tag="allorf_3538116_3538193"
                     /protein_id="allorf_3538116_3538193"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MRIHSIFIRMQGLYAQVICPTNATY"
     CDS_motif       complement(7032..7076)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRIHSIFIRMQGLYA"
                     /locus_tag="allorf_3538116_3538193_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(6999..7031)
                     /prepeptide="core"
                     /locus_tag="allorf_3538116_3538193_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.60"
                     /molecular_weight="1073.2"
                     /monoisotopic_mass="1072.5"
                     /core_sequence="QVICPTNATY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRIHSIFIRMQGLYA"
                     /leader_location="[7031:7076](-)"
                     /alternative_weights="1091.2"
     gene            complement(7114..7248)
                     /locus_tag="EG882_RS21115"
     CDS             complement(7114..7248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012117358.1"
                     /locus_tag="EG882_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PhrA family phosphatase inhibitor"
                     /protein_id="WP_003154881.1"
                     /transl_table=11
                     /translation="MKSKLLSGLLLVAVGFSFTQVIGHESHLENQADGTFHIAARNQT"
     gene            complement(7238..8374)
                     /locus_tag="EG882_RS17855"
                     /old_locus_tag="EG882_17855"
     CDS             complement(7238..8374)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389125.1"
                     /locus_tag="EG882_RS17855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17855"
                     /product="Rap family tetratricopeptide repeat protein"
                     /protein_id="WP_087920760.1"
                     /transl_table=11
                     /translation="MRMKQTIPSSFVGLKINEWYTHIRQFHVLEAERVKREVEREIEDM
                     EEDQDLLLYYSLMEFRHRVMLDYIKPLKEDPSQPEFSELLEDIEGNQYKLTGLLDYYFN
                     FFRGMYEFKQKMFLNAMMYYKRAEKNLALVSDDIEKAEFAFKMAEIFYNLKQTYVSMSY
                     AVQALETYQSYETYNVRRIQCEFVIAGNYDDMQYPERALPHLELALDLAKQEGNPRLIS
                     SALYNLGNCYEKMGDLSKAAEYFETSVSICRSEKFDNLPHSIYSLTQVLYKQNTTAEAE
                     KQYRLGLSIAREYNDELFVNLFQFLHALYGKEMDNASVRHTFDFLEEHMLYPYVEELAH
                     DAAKFYMKHGQPEKALTFYEKMVHAQKQIQRGDCLYEI"
     gene            8580..9047
                     /locus_tag="EG882_RS17860"
                     /old_locus_tag="EG882_17860"
     CDS             8580..9047
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417598.1"
                     /locus_tag="EG882_RS17860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17860"
                     /product="DinB family protein"
                     /protein_id="WP_025284602.1"
                     /transl_table=11
                     /translation="MTAQNQLVSHFLSHRNVTIELAEKISREHYDYKPAETSMSAQELV
                     KHMVYSFLMFANVINDGNASAIQNKPKEEAETDLVKLAETCTEKTTDILSQLTEEQLNR
                     EIDLTASFGRKVTGAALLQLAMEHEIHHKGNLFVYVREMGHTELPFYQQKS"
     misc_feature    9108..9122
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.28"
                     /tool="antismash"
     gene            9192..9956
                     /locus_tag="EG882_RS17865"
                     /old_locus_tag="EG882_17865"
     CDS             9192..9956
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389122.1"
                     /locus_tag="EG882_RS17865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17865"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_020955677.1"
                     /transl_table=11
                     /translation="MTVSIVFMGFFVGTLVGLTGVGGAALLTPLLIVLGINPSIAVGTD
                     LLYNSITKLFGVVSHWKQRTVQFKLVGYLALGSIPSATAAIGVLHLFPAFHQHQEQIIK
                     QALGYVLTLVAISIIARLFFDKRLRPNRWQQKTLEEKRTLMILIGVIFGFIVGLTSIGS
                     GSLFAIAMLYLFRMKTAEVVGTDIAHAFLLVTAAGLLNASFGSVDYLLVLNLLIGSVPG
                     VLLGSFFSPKFSPRPLQFVMAAIILISGIKLI"
     gene            complement(10001..12886)
                     /locus_tag="EG882_RS17870"
                     /old_locus_tag="EG882_17870"
     CDS             complement(10001..12886)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154888.1"
                     /locus_tag="EG882_RS17870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17870"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_124693085.1"
                     /sec_met_domain="DUF4135 (E-value: 5.2e-85, bitscore:
                     283.7, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-53, bitscore:
                     180.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTQNSDNYVYENSMLNIFKEEDYFEGFAQYYISIFKAQIVKEI
                     DRIPSESLLDKGCLVESILINYKKKIYYLAGKTLIHEFHQTFDEFDEKNESKNYDIFSE
                     RLKNSAFVEEILNNYPVLQDLISRSTSDFIRFTISIIKHWINDYKNIQQKFNLSFGKMR
                     KINMNAGDVHNGGKSVVIIEFENNKLVYKPRSLEIDVFYEKVIDYVNQYYQTNLKTPLS
                     LDQGEYGWQEYIQAEPCDNIEQVRNYYYQFGMHLGFIYAFQGSDFHFENIIACRDKPVL
                     VDLETLFQSSLFFSEENKENVNLMASAQVNKTILKSALFNYMSFPEDNGLTNIGGLINT
                     ENQKGEKEEVLHIKTDKISMRKKQYLFKRGRNLPVYKNNVAECFEFEREFIEGFKRIYF
                     ILKEDLYIRNLISDLNYAPIRIIVRPTYVYASFLETLLHPMYLKDYGERIRVLSFIKDA
                     YTKYDVFDSISPFEINDMMIGDIPYFNAPISEKRVYSNSIYVADTGIMKQSAKQEVLTR
                     LENMSEEDMHQQVSLINMALSSTAANLDIICKNQIDDFAPGYFKNDIQIKELIQIETDC
                     ILKQAIESEKYLQWVSIVSAPNGTLSVGPLSFGLYDGLAGVGHYFSAYDFIYNDEKVKP
                     ILCKIVNSINQIYEHSIYKTNFSAFYGSSSYIYFVNKMRDTGLFSENEVNSMCKAYLEK
                     LRQETAQITHTDFIGGLAGILKVVIQLGKYYRTELMEDTARAVCKEICKRAIQNRNEAF
                     WKSDADKNIVLAGFSHGITGICYALSEYYAHIEASEEVLRLIESALKYEDRFFDIKINK
                     WRDNRKNESDYSSAMWCHGSCGILLGRSRIYENVDGRIHVGYINESLDDTLLNGNSHRQ
                     GYSLCHGTMGNIDVLHAIKDLSLFKNRKQEIENTINIWVNHFKETLLKNGWQNGIRNDY
                     SGLGMMLGKTGQLFALLRLIDKEIPTPLALD"
     gene            complement(12973..13149)
                     /locus_tag="EG882_RS21120"
     CDS             complement(12973..13149)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="EG882_RS21120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417596.1"
                     /transl_table=11
                     /translation="MKKDFQALTPMTEEELKNLAGGSDATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       complement(13084..13149)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDFQALTPMTEEELKNLAGG"
                     /locus_tag="EG882_RS21120_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12973..13083)
                     /prepeptide="core"
                     /locus_tag="EG882_RS21120_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3391.9"
                     /monoisotopic_mass="3389.7"
                     /core_sequence="SDATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDFQALTPMTEEELKNLAGG"
                     /leader_location="[13083:13149](-)"
                     /alternative_weights="3409.9"
                     /alternative_weights="3427.9"
                     /alternative_weights="3446.0"
                     /alternative_weights="3464.0"
                     /alternative_weights="3482.0"
                     /alternative_weights="3500.0"
                     /alternative_weights="3518.0"
                     /alternative_weights="3536.1"
                     /alternative_weights="3554.1"
     gene            complement(13186..13362)
                     /locus_tag="EG882_RS21125"
     CDS             complement(13186..13362)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417595.1"
                     /locus_tag="EG882_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_017417595.1"
                     /transl_table=11
                     /translation="MKKEFLALELMTEEELKELAGGSEATPMTVTPTTITIPISLAGCP
                     TTKCASIVSPCND"
     CDS_motif       complement(13297..13362)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKEFLALELMTEEELKELAGG"
                     /locus_tag="EG882_RS21125_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13186..13296)
                     /prepeptide="core"
                     /locus_tag="EG882_RS21125_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="3.30"
                     /molecular_weight="3405.9"
                     /monoisotopic_mass="3403.7"
                     /core_sequence="SEATPMTVTPTTITIPISLAGCPTTKCASIVSPCND"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEFLALELMTEEELKELAGG"
                     /leader_location="[13296:13362](-)"
                     /alternative_weights="3423.9"
                     /alternative_weights="3442.0"
                     /alternative_weights="3460.0"
                     /alternative_weights="3478.0"
                     /alternative_weights="3496.0"
                     /alternative_weights="3514.0"
                     /alternative_weights="3532.1"
                     /alternative_weights="3550.1"
                     /alternative_weights="3568.1"
     CDS             complement(13386..13544)
                     /gene="allorf_3544503_3544661"
                     /locus_tag="allorf_3544503_3544661"
                     /protein_id="allorf_3544503_3544661"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MKKNFSALYETSEQELKELVGGQNSVSITTYPITNHICPTITVGC
                     ACPQRQV"
     CDS_motif       complement(13479..13544)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKNFSALYETSEQELKELVGG"
                     /locus_tag="allorf_3544503_3544661_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13386..13478)
                     /prepeptide="core"
                     /locus_tag="allorf_3544503_3544661_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3119.6"
                     /monoisotopic_mass="3117.6"
                     /core_sequence="QNSVSITTYPITNHICPTITVGCACPQRQV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKNFSALYETSEQELKELVGG"
                     /leader_location="[13478:13544](-)"
                     /alternative_weights="3137.6"
                     /alternative_weights="3155.6"
                     /alternative_weights="3173.6"
                     /alternative_weights="3191.6"
     misc_feature    13529..13543
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.96"
                     /tool="antismash"
     gene            complement(13570..15717)
                     /locus_tag="EG882_RS17875"
                     /old_locus_tag="EG882_17875"
     CDS             complement(13570..15717)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154889.1"
                     /locus_tag="EG882_RS17875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17875"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_124693086.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.6e-26, bitscore:
                     90.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKRKLPVILQRNQFDCGITCLAMVLSRAEGIKINPNKLKLNK
                     EIIGRDGTDLIEMKKISETFDYEFKAFSTDNITQLKELNKNHPLIVHWNHNHFVVVDAF
                     GTDSVKIIDPSSGRLTITLEEFKTFYNGISIMLIRKNERERKDKSASSLKDVSSFRKIG
                     KYLLKDKKILGFIISFTFIFQALNLMTPFLTQYIIDSFIDGNEKSLPIPMLFMIVIVSI
                     VLFFSLSLIRMKFIIKLQLKINKSMTDKIIHKIFSLPLKFFEANTAGDISTRIHNIAVI
                     REVISRLASTLILDISLIFVFFIVMFVYSPILAFIVLLGAGIQVMSTKILLPKIEMFTK
                     QEVNSQSNFQSQLIEILRSMTFIKTIGETRNIESQLNYNFNHQLDYFSKRMNYSSLLGA
                     VSNAINLSLPLLILIVGTWSAASIGLTLGAVIAFSNIAGRFMSPLGSIIGSLESIKLVE
                     EMVDRVEAVLDEKDEEVNDKSNELFNPAAHNISLKNIDFSYNGNNYILNNINLMIRPRE
                     KITLIGKTGCGKSTLIKIIAGLYQKTAGEICYGEFKIEDVNMVKLRETLGYIVQDVNLF
                     NDTIINNIKYFNEKTTMEEVVQAAKEACIHEDIIKMPMGYHTMIGENGITLSGGQRQRI
                     SIARVLAKNPQILFIDEGTSNLDKDTELKILNNIYKKDITVISITHRTEWLEFSESVYE
                     IENGNLKTIKAKYESQLQQTY"
     gene            complement(15707..18889)
                     /locus_tag="EG882_RS17880"
                     /old_locus_tag="EG882_17880"
     CDS             complement(15707..18889)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154890.1"
                     /locus_tag="EG882_RS17880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17880"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_032871263.1"
                     /sec_met_domain="DUF4135 (E-value: 1e-98, bitscore: 328.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-61, bitscore:
                     204.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSLTNILLSKEKKAAVSQFDENENLFDQNLELIYKNDIQMAQES
                     IHNVLSIQSIDKVKNLYQTPLHKSAFTVHVFENLKKGIAHQAIKKEDVNEEIMFHVFAL
                     KVSSYFNDLLKKSKFPSYDYLLEQPALFHHSISNQLEKIILKVSYRTLVLDMNMNREKG
                     FLAGETPKEKYGYYNKTLLCSPEYLKSFFQQYPVLLRVIGNELRKFKKFILEFISRFEK
                     DQPELLSLFGFSEQVKLRDIEVGMGDSHSDGRKVTKITLNEGKLIYKPRSLEIDLLYKK
                     IIEFLNEKIRDHDIKLSTPNVLSRDGYGWTEFISFKACNCLKDIQNFYQRTGAQIGLLY
                     ALKAVDFHSENLIANGSYPVLIDLESLFHPAYQKKKDGMDAYEKAETQLHESVRALGLL
                     PFFFGGKADISGIGRKGKAKSIIKVPQLINLKTAEMSVKRDYVEIDTANNHPMLENKFV
                     YAKDYVEELKQGFSKAYMTILKHASELIRIIEKSENKIYVRFISKPTIKYSALLELSFH
                     PRFLHNSIDREIFLSKIWERPKPEDEYQSIVKYEFNDLINNDIPYFKVKLNEKDLLSSK
                     NKKIENYFPKTPAQSVKERILNLSKDDLKFQLYVIELSMLASEDDRQIVLKEFITKEPG
                     QYVNVFSSNQESILIEKAEELAAYIYNQSYKAHTDKGSSYSWLNATPIGVDEIQWNLSV
                     MGDTFYDGLSGMAFTYLALWRVTKKEKYLDIAEKIMKDVISRFIDIEMKPDEDSTMSVG
                     AFSGVSSIVYTLMNFYMYTKREKYKQDAKQIAQLIPSLLPYDKELDIIGGTAGALIVMV
                     RSFEIENDTFFLSLAEQCGSFLMKQATFLDGNLVTWEGIANKPLTGFSHGNAGMIYALQ
                     LLEKHSKHQDISMYIRKGLAFENSKKVNGNWLDLRKPVNEAATSAWCHGSPGILLSRLE
                     LKDSKHPDIAEEAKKDLNKAVSNIFYDGFGREQSLCHGDMGNALILIEYGKKTGESQFV
                     NIGKNLILESVQDKNIGFYQCGVGRDVETPNLMLGLAGIVYGMLYAADVKLPNILNLEI
                     GCVDTLGDFYEN"
     gene            complement(18976..19158)
                     /locus_tag="EG882_RS17885"
                     /old_locus_tag="EG882_17885"
     CDS             complement(18976..19158)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154891.1"
                     /locus_tag="EG882_RS17885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17885"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_032871261.1"
                     /transl_table=11
                     /translation="MNEKMYRFAGDLREELEEISLNEISGGGGAEQRGISQGNDGKLCT
                     LTWECGLCPTHTCWC"
     CDS_motif       complement(19078..19158)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNEKMYRFAGDLREELEEISLNEISGG"
                     /locus_tag="EG882_RS17885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18976..19077)
                     /prepeptide="core"
                     /locus_tag="EG882_RS17885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.40"
                     /molecular_weight="3435.8"
                     /monoisotopic_mass="3433.5"
                     /core_sequence="GGAEQRGISQGNDGKLCTLTWECGLCPTHTCWC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNEKMYRFAGDLREELEEISLNEISGG"
                     /leader_location="[19077:19158](-)"
     misc_feature    19321..19335
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.27"
                     /tool="antismash"
     gene            complement(19351..20016)
                     /locus_tag="EG882_RS17890"
                     /old_locus_tag="EG882_17890"
     CDS             complement(19351..20016)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154892.1"
                     /locus_tag="EG882_RS17890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17890"
                     /product="response regulator transcription factor"
                     /protein_id="WP_124693087.1"
                     /transl_table=11
                     /translation="MIKILLIDDHIGVAQGTKAILERSNKMGVTILSCCKEVLNHLKHY
                     EYDLLLLDLYMPELNGMELSKMILRESPDQKIIIYTGFDISVHFNLLVEVGVSGFISKS
                     STEEHMIKVIESVIEGDTIIPTHLFKQLRRTEANTFNIDKLEDRIRDITLNEREQDILA
                     GVAEGMTNRELSAKLLISQRAVEYILTGVYNKLGVKSRTEALIKANRYSLISMKTIYE"
     misc_feature    complement(20015..20029)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.46"
                     /tool="antismash"
     gene            complement(20028..21278)
                     /locus_tag="EG882_RS17895"
                     /old_locus_tag="EG882_17895"
     CDS             complement(20028..21278)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154893.1"
                     /locus_tag="EG882_RS17895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17895"
                     /product="ATP-binding protein"
                     /protein_id="WP_122503841.1"
                     /transl_table=11
                     /translation="MKDNWVKLNMEQFARAFVFSLLLLFMLLLITDSQLQFKQYSLFFV
                     LSIFGSSCLCFTYDDRNKTYLRSLFRFSELCQEGSDADQLIKELTNEIQSVFSGKQIAL
                     INYDKKTLKLKGNHIQVPNINISNFKIGEIRETASGSILFIGEKCDTFVFIHLSHKGHP
                     IKIRENEADWLRMLAFCTASALQNKLLIQKKIDEIIIDNQHKCKSAVLSKVLFSISEIE
                     RTKLAQDIHDSIIQELIFVCRELEYHVEKYKDIYYIREILLGNIQYIREKCFDLRPPFL
                     MEMGLLRSIQVLIDKHKSNYQLDIEFFVDVKDDSIFTEDITINIYRIVQELLTNAVKHS
                     KASYIVLTMIQKQTSLMFVYEDNGIGIDWNKVNSKTNSFGLTGIKERINCMNGIHNISS
                     GVNEGLLLRFEISTKNE"
     gene            complement(21344..21535)
                     /locus_tag="EG882_RS17900"
                     /old_locus_tag="EG882_17900"
     CDS             complement(21344..21535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154894.1"
                     /locus_tag="EG882_RS17900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17900"
                     /product="hypothetical protein"
                     /protein_id="WP_003154894.1"
                     /transl_table=11
                     /translation="MEQVIFVISMLALGVTLVTFFGMILNDGLRGVLNFSRKPVKFMTG
                     SFLVYIVAFAVYILISVK"
     misc_feature    21492..21507
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.85"
                     /tool="antismash"
     gene            complement(21553..22284)
                     /locus_tag="EG882_RS17905"
                     /old_locus_tag="EG882_17905"
     CDS             complement(21553..22284)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417590.1"
                     /locus_tag="EG882_RS17905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17905"
                     /product="ABC transporter permease"
                     /protein_id="WP_032871255.1"
                     /transl_table=11
                     /translation="MSLLVRNEFLKLKRLKSIYVIFFLSFLPFLINGIGLLAMNENTDW
                     NKFYMFVFNQYSILFPTVIFIFSGFYFYLEFKNRTMLNWMSYPYHKFKLILSKLAAAFL
                     FLFLISAVNHIIHLSTLFFFFREDVSASDLLRLIATSFTSTTLSLLTIPIAALIAFLSK
                     NIVVVMITGVASFLIMTILLASDVSIVFPFSFIYRFSIQIFESNMGYSDSILLVWGLLI
                     MGLYVLVSLSGLYVYSKKNRM"
     gene            complement(22265..23200)
                     /locus_tag="EG882_RS17910"
                     /old_locus_tag="EG882_17910"
     CDS             complement(22265..23200)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417589.1"
                     /locus_tag="EG882_RS17910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17910"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_122503840.1"
                     /transl_table=11
                     /translation="MGKADPALISKGINVSIKKKEILHDINLTLEKGKIYGLLGPNGAG
                     KTTLLKVLLGIFPPTSGEVIFEGNNLYRNPNNDVIQSIGSIIEFPGFYENLTLFENIKL
                     HLNYLKRSASDEEINEILGKVGLFEHKDKLFSQTSLGMKQRLGIARAVAHAPALLLLDE
                     PTNGLDPYGIKEVREMLIQEVMKNGTTVVISSHLLSEINLMADELLIMNKGEIIFESAF
                     MKNTQHLYLYKIPAEAGINWADIEKFADHVISRNKQQFEFISVIHPSEMKEKLNSCGFN
                     KESIDGFKLSLEDLYLKLLAKEKGHESVSA"
     gene            complement(23320..24678)
                     /locus_tag="EG882_RS17915"
                     /old_locus_tag="EG882_17915"
     CDS             complement(23320..24678)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017417588.1"
                     /locus_tag="EG882_RS17915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17915"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_025284598.1"
                     /transl_table=11
                     /translation="MKLSTKYLINIVASILFFPIAFLGVNFLYYVTLTYLIDHQGQVHY
                     EPNKLESDWKSDVEDFSGKSNREITSAFPHMKQYKHSDIVWINDKGKVMFSNSERLAKK
                     GEVIHLSELIKMIEQNEKKYLLLSAYVNGSEDSGYAFLETPRSIIGSQWEVMRAKYSYI
                     WFIALIFVCSLFVINSWMFFAKIQKRLISLGYHMKKQDNDGIPEFVTVKQKDELGQVEY
                     SFNQMVEELRNSRQKEREEGEIRKNLIADLSHDLRTPLTVIRGHTFTLKNEISSENGKH
                     SLGIINDKITFMGELIDNLSSFSLLAAGKLPLHKKSCDILKIIRSSLTAWYPIFEKEHF
                     TIDIDLKENIVWEIDETWLKRILDNIFQNVLRHAHSGKYVSVQTKLIENKPVIIIEDRG
                     PGMNNKSERKGAGIGLSIINMMLKQMGLEHKIKSNQNGTIFIIYPNSSEYVKP"
     gene            complement(24675..25346)
                     /locus_tag="EG882_RS17920"
                     /old_locus_tag="EG882_17920"
     CDS             complement(24675..25346)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003154900.1"
                     /locus_tag="EG882_RS17920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17920"
                     /product="response regulator transcription factor"
                     /protein_id="WP_015417275.1"
                     /transl_table=11
                     /translation="MNNILYIEDDQEIGQFVKGDLEDRGYMIIWLTSSYNYETYIEKAD
                     LIVLDIMMPGLDGFTIGQRMKKTHPQIPLLLLTARTGLEDKLKGLGFADDYVTKPFHPD
                     ELAARIEVLLRRFDKTAIHELKLKHLSVHLKEKRILNHQSHEEIFLTDKQLRIFLLLLR
                     HPNQILTKEQIYENIWEQPYIEGDKTLMVHIRHLRQKIEINPNEPEILETIRGIGYRIK
                     Q"
     gene            complement(25530..27023)
                     /locus_tag="EG882_RS17925"
                     /old_locus_tag="EG882_17925"
     CDS             complement(25530..27023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389121.2"
                     /locus_tag="EG882_RS17925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17925"
                     /product="altronate dehydratase family protein"
                     /protein_id="WP_099566659.1"
                     /transl_table=11
                     /translation="MKEVIKIHKNDNVLLAMRHFNKGERLHTDGLTIEVKDPVKRGHKI
                     ALQTIEENGSIIKYGFSIGRATRRISAGEHIHTHNLQTNLSDVQEYTYSPRFEDNPFTN
                     ENRTFKGYRRENGTSGVRNELWIVPTVGCVNGVAEKILQRFVKEAKDIAPFDNVLVLKH
                     QYGCSQLGDDHENTKQMLMNAIRHPNAGGVLVLGLGCENNELAAIKETLSEVNGDRVKF
                     LESQAVTDEIEAGTALLKEIHLAAKGDKREEIPLSELSIGLKCGGSDGFSGITANPLLG
                     RFSDYLIAQGGSTVLTEVPEMFGAETILMQRAASEEVFHKTVRLINDFKQYFMKHEQPI
                     YENPSPGNKEGGISTLEDKSLGCTQKAGLAPVSDVLTYGETLKTKGLTLLSAPGNDLIA
                     SSALAAAGCHIVLFTTGRGTPFGTFVPTVKVSTNTDLFQSKPHWIDYNAGRLAEDQTTE
                     DHIVRDFIQYIIKVASGEFVNNEKNDFRELAIFKSGVTL"
     gene            complement(27020..28465)
                     /locus_tag="EG882_RS17930"
                     /old_locus_tag="EG882_17930"
     CDS             complement(27020..28465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015417273.1"
                     /locus_tag="EG882_RS17930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EG882_17930"
                     /product="tagaturonate reductase"
                     /protein_id="WP_124693088.1"
                     /transl_table=11
                     /translation="MQQLNKKMCGEYIQYPEKVLQFGEGNFLRAFADWQIDQLNQLTDF
                     NGSVVAVQPRGSEKIKRLNEQDGLFTLFLQGIKDGKPAEEHMIVKSISRGIDLFSDYDS
                     FKRLAAQEDLRFIISNTTEAGITFEKGDRLEDRPQKTFPGKLAAFLYFRYKAFAGDAEK
                     GCIMLPCELVEENGRKLKAAVLQYAGLWELEPGFTQWIHDANIFCNTLVDRIVPGFPVD
                     TAEELTDFLGYEDRLLVVGEHYYLWVIEGPEQLQNELPFAEAGLNALITSDLTSYRTKK
                     VRILNGAHTALAPVALLYGLQTVREAAEHEVTGRFIEELINEEILPVLQMEGVIQYAAD
                     VLQRFKNPYIYHYLQSITLNAAAKFKTRNLPTLKAYIEQEGRLPEKLVFSFSAMIYSYW
                     NGPNKPADGEEVLNRFQMARSRCKDDMFQAASAILGEERLWGENLNHLPGLTERTAFFL
                     SVIHKRGMKHALHECCGKKGEVK"
ORIGIN
        1 taaagctttt cacataataa agacaaaaca gccgctggcg ttcgtttaac tcatcacctt
       61 cgcccggggt gttttttccg ccgctttccg cgttcttatg aagagcctcg tcccagcgcc
      121 cttctttttt ccatctgccg atcgttcttg cggatacgcc tgatttgccg gcaagggcgc
      181 gatttgtgat gcggccttta tgagactgat agattgtaaa tgcctgtttt ctttttgcgt
      241 ttttcatgct acggcatcac cgccacctcc gacatgattg tctataataa aaagcggctt
      301 ctaatcgggc cgctttttgt gatcgtctgt tcacttctag gtggcaaacg tatgacaact
      361 tatgaagcag gcgattgatt tctttgttcc tgctgttttt gtatttttag aagcgcccgt
      421 ttgaccgtcg tctgtacggt tgatttcttt acattcagca aggcggcgat ccgttcatat
      481 gaaaagcatt ccgctttgtg gagcagcagc atttcttttt ctctatccgt taaaacggct
      541 aatgcgtccc gcagtctgat tctgtcttct tcagtcacat tcccggaagg ttcaaacatc
      601 agcgcctgcg aataggtttc tatgattctc ggatctttaa tcagcattct ctgataagcg
      661 tctctgcggt ctatcgctct tcttatgccg ggctgccggc ctttttcaag ccattcgatg
      721 acatattcca catctgtaat gatcgttctg atgatttttt tatctttcag ttcttctgaa
      781 gtaagcaccg tttcatcggc ttcctccagc tgcttgtacc actttttcgt ctctttcagc
      841 gtgcgtttat attcaaatag taagtcttcc atgcagatcc tcctcttttt cggaacaaaa
      901 aaaggacacc aaccaatgcg cagcatgtac gtgattgatc agtgtccgca ggctttccgt
      961 cttggacgta ttctgttttt ttcgattaat tcaatttaaa gccgatttca tattcgaccc
     1021 gggccagatc cccttttcgc gtttcgacaa gcgttttgcc gtgctccggc gcttcggcga
     1081 gccatgcttc cttcttcagt ccgtctataa taatcacccg aaccttgcct tcttccagct
     1141 ggctttgtaa tgttgtatgt tcaatgtcag tcagtttttt aggattcatg ttttacgtcc
     1201 tccgtttttt tcaggatgtt tacttcatgt atgaggcttc cgagctcatt tatgaacgct
     1261 tctttttctt cagaactttc tccccggagc aggcggagag ccgtttcggc cgcctcaaaa
     1321 agttccgggg cttttgccat caatgccgcg ttgatctgct gagagtatga acttaagttg
     1381 aaaacggccg cgatgagcct tccgtttgaa taagggaact tctctttatc cgcttcgctg
     1441 taagcggaat aaatgtaaat ggttttttct tctccgctgt gtacggcccg ccatggagcg
     1501 gggctgtgtt tttcttgcaa tggttatcct cactttccat cagcctcatg ccatgcttca
     1561 atttgctttt ctatccgttt cgccctgaac agcaggcaaa aaagccattt aatatattta
     1621 tacacgtgca tcaagcctcg cttttgcgtc ttgaaccatt cgctcaagac gtttaatgac
     1681 cggcgttaaa tcagtgcctg ttttgcagtt cgggcaaggg tgaaagacag cgccgaaacc
     1741 cgtttccgtc acaatgacct tcttcggccc gcacagctta cacattatct cgccccctct
     1801 aatctgtggt ttacgtcaaa tgaattgcca ttaatgatga ctaaataatc gctgcacatc
     1861 tcataaattc ttgtgcccaa ggcttcatca acctgcacca gtccgtcaca ggccagctcg
     1921 ctcgagataa aaaccggctt atgatttaaa tagcggtaat tcacgacggc gtacatttgt
     1981 tcaatctgcc aatcggtcgc ccggggtttt ccgttcagcg gtttgaacag atcgtcaata
     2041 aaaagcacat ccgcctgttt catacggcca agctttgcat caagcagatc aaaatcattt
     2101 tttaaatccg taaatccctc cacaaaagga aaatacagca cgggtgtctg cttctgtctc
     2161 atgacataat tgctgagagc ggtcaaaaga tgggtttttc ccgaccccgg acgccctaaa
     2221 agggcaatgc tgtttttccg gcagttttta atcttgtcga agttttcaac atattcaagg
     2281 gcgcactcat atgcgtcgac gactgcctga ggcttgcccc gcgtgataaa tcctttgaaa
     2341 tccagcttcc gaaaggcgcc tgtaatctca cttgcgctga ggatgcgctc tgcttttcgt
     2401 tcggcggcgc agcggcactt aacccacaca tccattccca gctggttttt gagataaccg
     2461 ccctgatctt tacagagcgg acagtcaaag cggctttcgt ctgattcttc cggtctgtcc
     2521 gccagtaatg gacgttttcc gtttttcagg tcggccagta tctgctcgat cgttcgtttt
     2581 gtcatgtatc gtattcctct ctttttttgt tgtgattgtc cttcccgcaa ttcgtgcatt
     2641 caagcggtct tccatatact tggcgcaata gctgaaagcc ttgatcgttt cagctgaaga
     2701 tgtgcgccgc tgttcaaaag cggtaaagca ttcgccgagc catttgattg cttcttgtgc
     2761 tgacgcaccg agggaaacaa tacgggcgat ggcctgataa tcccggggcg acgggtatac
     2821 gctccgcccc tcctgtgcag accttaatct gataaaatgg gcggcaatgt cgttaatcgt
     2881 ttcttcagca gtatgatttt ttgttatatc tatttctctc cggacatttt tgtcccggtg
     2941 atccgccgat attgtccggt cagttgcttc cgggcgggtc aatgtctttt tcggcgtgaa
     3001 tcttttcgag tgctttacgg agacgatgag tccgtaaggg gcgcggacgg ttttgatata
     3061 ttcatgctgt tccaaaacct caagccaccg tctgacggtt ttttcgctga cggcaaatac
     3121 atcggccatc tctcttgctt ttacgggctt atgaccaagg acgatccccc actttacacc
     3181 gtcttttacg tgttcctttg tcgttgagct gatgaaccat aaaaacagcc aaatggcgga
     3241 ccctattttg tcataatgtt ctgaattcag taatccggaa tagatgaaaa acgggtagct
     3301 tttacgattc ataagggacg tctccgtttg tcttcagacc tatatagcgt tcatactgca
     3361 atcggttatc aaatcggaat accggaagtc cgcaagcggt aaaagatatc gaaccgcctg
     3421 cttttcctaa acatctctgg tcagccggat tgctgctgaa acggatgatt atcggctgca
     3481 tctctcaccc tcctgatcaa ttttttatcg tatattgata cattttgtat cattatgatg
     3541 ttgattatat acgatacatt tcgtatcatc aagacctttt tgatactttt tttatcatct
     3601 ctttattttg atacattttg tatctataat cataagtaac ttagggtgtt gaaaaaagag
     3661 aggtcattcg gatgataggc ggaagattaa agagtctcag aggaaagaaa acgcaggaag
     3721 aagtcgcaaa tcatatcggt gtctcgcgcg ccagatattc tcattatgaa aacggccgat
     3781 ctgaacccga ttacgacacg ctgcaaaagc ttgcggatta tttcaaagtg tcgactgatt
     3841 atttgttaac cggaaaagaa ccttcagatg aagacatgtt tgccgatccc gacctgcaga
     3901 tcgcatatcg ggacatgcag gacttttccc cggagagcaa acagcaggcc attgaattca
     3961 ttaattattt aaaagaaaaa gagaaaaacc gcaggccgaa acataaataa tccgctcttt
     4021 tcctttaaac tgcttaacgt tcagccgata taaaagctga atgtttattt ttaaaagaaa
     4081 agggaattga ttcaaagtcc gatcagggct tttctttctc gcttaaaaaa agaacatatg
     4141 ttcgaaaggg tgtattcaat tgggcgattt tttaacacat cttgaggaat acgtcaaaaa
     4201 cttatattgc cgcatgggaa tgaccgcccc tctccatatt gatatgcaga tgattgccaa
     4261 ggagcttgac atttggattc attttgaaga tacgcacagt atgatgctga agcgggacgg
     4321 catgtacagc atcgtcctga atcaaaaaaa gtcacccgaa gagcaatggc aggattttgc
     4381 gcacgaactg tgccatgtgc tgaaacatac cggcaaccat tttcatatga acaagctgtt
     4441 cagggaactg caggaatttc aggccaacca ttttatgtac cacttctgtg tgccgacctt
     4501 tatgctgtta aacatggagc ttccccagcg aaggagccat gccgttattt taatcgcagc
     4561 cgctttccgg gtgacggcat catttgcgga aaaaaggctg gagctgtttg aacggcgtaa
     4621 agcaggtatt caatttcaga agcggctcgc ttgtctgtta tccgacaagc ggccgaatgt
     4681 gtattatgaa agcggacaga cacacttgca tgccgctgaa gaaaaaacgc cgtattttat
     4741 tgaaaattag cgatactctg ccgccagagt gtcggcattt taaatcgcag gaaaggtttt
     4801 ttgcatcatg acgctgttct caccgtgctg cccgccaagc acttcttgca ccgtatagct
     4861 ccagtaaata taagaacggg ccccctgttc atttatcata aaaaccggcc ttcacggctt
     4921 ctacataccg aaaaaacaga tcggttggcg tatatttttc tccccggcag ccaaaattac
     4981 tgaacagcgc gtgtctctgc gccgtgctca cttccaattg cagccccatt ttcctttttg
     5041 tccgattgac aatgttgccg ggatttacac ctgccagccg atcattcttc tctgtcagct
     5101 cggcatcaaa ccccgcttca cgcagcagat cacaaatcag tcttgctttt tccagatccg
     5161 cgcccccgac gagtgtattt gcctttttca gatcatgata cccatgaaaa gccaatgcgt
     5221 aatgatgggc ggtcactttt tctaaagcca ggggctcgtc aaagcgtgtg cttgtcaaat
     5281 ggagagaacg gttatcgcac cgcttcgttc cttcaaataa ataaattgag ctttggtcag
     5341 aaaatgcccg caccagctca ctgacacccg gctcaaccct gccgccgtgg ggagcgagga
     5401 cgatacattt acttccctct ttttcttcat aaataattct gtattccgat tcagcagcag
     5461 atagggctgc gaaattatca tatctatctt tcatgtgtaa catactctcc ttttccacag
     5521 caccagttta ctctactcat ctgggaatgg aaaccttttt atagtatgat ttgatagaat
     5581 acgtatcagg gggggatata tcatggggtt catcaatgga ttgctgggca atgcgtcgac
     5641 aatatcgacg gctgaagcaa aagcagaact ggctcgtatt ctgctggaag gtgagaatgt
     5701 caatgccgca tttaagcttg tccgagatat cattgtcttt acggataagc gtcttattct
     5761 tgttgataaa cagggactca cagggaagaa aacggagatt caatccattc cgtacaagag
     5821 catttccaga ttcagcgtag aaactgccgg ccgctttgac cttgattcag agctgaaaat
     5881 ttggatttca ggcgcggaac ttcccgctgt ctcaaagcag tttaaaaaag atgaaagcat
     5941 ttatgatatt caaaaggccc ttgcagcagt ttgtatgtaa gaagaaacgg aagcccgggg
     6001 ggcttccgtt ttattgatta cagtttttct tcaattttcg ccttcgtttt cgggccgtaa
     6061 attccgtctg ccgttaatcc gctgacggat tgaaaacgtt ttacggcatt tgccgttttc
     6121 ggaccgtaaa cgccgtccgc cccatgattt tttgctcctt tatcaggata aaaataaaga
     6181 gcggataaag cgttttgcac ttgttttacg tttgtccctt tcgtcagcgg tttcgtcact
     6241 ttgatcacac cggatggaag cggataggaa gacacagcct gactttttga agaagaaccc
     6301 gtctgagcga gcttgatcac ttgtccgact gtaatgtgat tcggatcggt gatatggttg
     6361 atgctttgca gcgattttac gctgacaccg tgcgatgcgg cgatttccga taaggtgtcg
     6421 ccttttttca catggtattc agacgcggaa gaagcaatag aggctttttt cgccggcata
     6481 ctcccgctta attttttttc aatcttcgcc ttcacttcat cccagcggcc ttcagacaaa
     6541 atgcggtgcg ggcagtactt tccgttccag tcctgatgct ttctgattct gtcaatcccc
     6601 cagccccgtt ctttcaaaag ctgcgccgcg aacgcaatcg ccagttcttc tgcggctctg
     6661 taccgttcgc cgcctgactt gctgtaacag atttctatag caatcgactt tcggtttccg
     6721 gtaccgttcg tgccgtctcc cgaatgccag gcattccggt ccaacggaat tccctggatc
     6781 acttctttgt catcaaccgc aaaatgatag ctcgttgatt cgctgtttcc cgtcatatag
     6841 ctgatttcat tagcggcgga tgcgtcgttt gccgtgttat gaatggtaat atactccggc
     6901 gtcatcggat tcggacattt taacgcatat ttatcagccg atacgagccg ttttttcact
     6961 tcaatcccca ctcttcatct ctccttatgc ctttttcatc aataggtggc attcgtagga
     7021 cagataactt gagcatatag accctgcatt cggataaaaa tggaatggat acgcacgcaa
     7081 aaaataagac ccttccacag aagggtcttt atgttatgtt tggttgcgcg cggcaatatg
     7141 gaatgtgccg tccgcttggt tttccaaatg gctttcatgg ccgatcacct gtgtaaagct
     7201 gaacccgaca gcaacaagca gcaatcctga caacagttta gatttcatat agacaatctc
     7261 ctctctggat ttgtttttgg gcgtgcacca ttttttcata aaacgtgagc gctttttcag
     7321 gctgtccgtg tttcatgtaa aatttggcag catcatgcgc caattcttcc acatacggat
     7381 acagcatgtg ttcttccaga aaatcaaacg tgtgcctgac ggatgcgtta tccatttcct
     7441 tgccgtataa cgcatgtaaa aattggaaca gattcacaaa caattcatca ttgtattcgc
     7501 gggcgatact gagcccgagg cggtattgct tctctgcttc ggctgtagtg ttctgtttat
     7561 aaagaacctg tgttaatgag taaatagaat gcggaagatt atcgaacttt tctgacctgc
     7621 aaatggaaac ggatgtctca aaatattcgg ctgctttaga gaggtctccc attttttcgt
     7681 aacagtttcc gagattatat aaggctgaac tgataagacg gggattgcct tcttgttttg
     7741 caagatctaa agcaagttct aagtggggca atgctctttc tggatactgc atgtcatcat
     7801 aattccctgc aataacgaat tcacattgga ttctgcggac gttgtacgtc tcatacgatt
     7861 ggtacgtttc aagggcttga acggcataac tcatggagac gtaggtttgt ttcaggttgt
     7921 aaaatatctc ggccatttta aaagcaaact cagctttctc gatgtcatca gaaacgagtg
     7981 caaggttttt ttcagcccgt ttgtaataca tcatggcgtt taggaacatt ttctgtttaa
     8041 attcgtacat tcctcgaaaa aaattaaagt agtaatcaag cagtcctgtc agtttatact
     8101 ggttgccttc aatgtcttcc aataattctg aaaactcagg ctgagaaggg tcctctttta
     8161 agggcttgat gtaatccagc atgacacggt gtctgaattc cattaatgaa taatacagca
     8221 gcagatcctg atcttcttcc atatcctcga tctctctctc tacttcacgt ttgacgcgct
     8281 ccgcctcaag gacgtgaaac tgccggatat gggtatacca ttcattaatt ttgagcccga
     8341 caaaagagga cggaatagtc tgcttcatcc tcaataaatc cccccttttg gaatgaccga
     8401 gatatgtcat attttatcat atttgctaga aaaagaagaa cgcaaaaaga ccgcaattgt
     8461 cgaatttcgg atatccgcaa cgatttatct ccgtcacaag cttattgctt gtttcttccg
     8521 tgccgttgat atagcatatc cttgcagctt tttattctgt attaaatggg ggttttcaca
     8581 tgacagcaca aaatcaattg gtcagccact ttctgtcaca tcgaaacgtg acgattgagc
     8641 tggcggaaaa aatcagccgc gaacattacg attacaagcc ggcagagaca tcaatgtccg
     8701 ctcaggaact tgtaaaacac atggtttatt cttttcttat gtttgcaaac gtcattaacg
     8761 acggaaacgc atcagccatc cagaacaaac cgaaagaaga agcagaaaca gacctcgtca
     8821 aactggctga aacgtgtact gaaaaaacga cagacatcct gtcacagctg acagaagagc
     8881 agctgaaccg cgaaattgac ctgaccgcct ctttcggcag aaaagtgacc ggcgcggctc
     8941 tccttcagct tgccatggag catgaaattc atcataaagg caatcttttc gtgtatgtca
     9001 gagaaatggg ccacacggaa cttccgtttt atcagcaaaa atcataatcc ggccatccgc
     9061 cggtctgcga cataacagca ggctggcgga ttttttgttc tgtataaaat tttccgaaaa
     9121 tttaattgat taccgcctct taatcatata taatctgata aaaatagtag gattattcag
     9181 gaggcacaca gatgacagta agcattgtgt ttatgggttt ctttgtcgga acgcttgtcg
     9241 gattgacggg tgtgggagga gcagcgcttt tgactccttt actgatcgtt ttggggatca
     9301 acccctcaat cgccgtcggc actgaccttt tatataactc catcaccaaa ctgttcggtg
     9361 tcgtttctca ttggaagcag cgcaccgttc aatttaaact tgtcggttac ttggcgctcg
     9421 gaagcattcc cagcgcaaca gccgccatcg gtgttcttca cttgtttccc gcttttcacc
     9481 agcatcagga gcagattatc aaacaggcgc tcggctacgt actgaccctt gtcgccattt
     9541 ccattatcgc ccgccttttt ttcgataaaa gactgcggcc gaaccgctgg cagcaaaaaa
     9601 cgcttgaaga aaagcggaca ctcatgatac tgatcggcgt cattttcggc ttcatcgtcg
     9661 gcctgacatc tattggatcc ggctcattat ttgcgatcgc catgttatac ctgttcagaa
     9721 tgaaaacggc agaagtggtg ggaacggata tcgcacatgc ctttctgctc gtaactgctg
     9781 ccggtctgtt aaacgcaagc ttcggaagcg tcgattacct gcttgtattg aatctgttga
     9841 tcggctctgt gccgggtgtg cttctcggca gcttcttttc gccgaaattc tcaccgcgcc
     9901 ccctgcagtt tgtgatggcg gcgattattt taatcagcgg aataaaatta atataaaaaa
     9961 gcgtccttta caggatcgct ttttcatttg ggaaatcccc ttaatccaaa gccagcgggg
    10021 tgggaatttc tttatcaatt aatctcaaga gtgcaaataa ttgtccggtt ttccctaaca
    10081 tcataccaag tcccgaataa tcatttctta ttccattttg ccagccattt ttcaataggg
    10141 tttctttaaa atggttaacc catatattaa ttgtattctc aatctcttgc ttgcgatttt
    10201 taaagagaga taaatcctta atagcgtgaa gtacatctat attccccatc gttccatggc
    10261 ataatgagta gccctgacgg tgggaatttc cattcagcaa tgtgtcatct aaagactcat
    10321 taatataccc gacgtgaata cgcccgtcta cattttcata tatcctgctt cttccaagaa
    10381 gaataccgca agacccatga caccacattg cggaagaata atccgactca ttttttctgt
    10441 tatctctcca tttatttatt ttaatatcaa aaaatctatc ttcgtatttg agagctgatt
    10501 caatcagtct gagtacttct tcagatgcct caatatgcgc ataatattca gatagtgcat
    10561 aacaaatccc agtaataccg tgagaaaaac ctgctaaaac aatattctta tccgcgtcag
    10621 atttccaaaa tgcttcattt ctattttgaa tcgctctttt gcaaatttct ttacaaactg
    10681 cccttgccgt atcttccatt aattcagtcc gataatactt gccaagctga atcacaacct
    10741 ttaatatacc tgcgagtccg cctataaaat cagtatgtgt tatttgcgcg gtttcctgac
    10801 gaagtttctc taagtatgct ttacacatac tattcacttc attttccgaa aaaagtccgg
    10861 tatctctcat tttattgaca aaatagatat aagaacttga cccgtaaaaa gcggagaaat
    10921 ttgttttata aatgctgtgc tcatatattt gattaattga atttactatt ttacaaagaa
    10981 tcggcttgac tttttcatca ttataaataa aatcataagc tgaaaaataa tgccctactc
    11041 cagctaaccc atcgtacagc ccaaaactca gcgggcctac ggataaagtg ccattgggag
    11101 ccgagactat tgatacccat tgaagatatt tctccgattc gattgcttgt tttaatatac
    11161 aatctgtttc tatttgaatc agctctttga tttgtatgtc atttttaaaa tatccaggtg
    11221 caaaatcatc aatttgattt ttgcaaatga tatccaaatt agccgctgta gagcttaagg
    11281 ccatatttat taagctcact tgctggtgca tgtcttcttc tgacatattc tctaagcgag
    11341 ttaaaacttc ttgtttagcg ctttgtttca taattcctgt atccgccacg tatattgaat
    11401 ttgaataaac ccttttttca ctaataggag cattaaaata gggtatatca ccgatcatca
    11461 tatcattgat ctcaaatgga ctgatagaat caaatacatc atattttgta taagcatcct
    11521 taataaaaga taaaaccctt atcctttctc cataatcttt taaatacata ggatggagga
    11581 gggtttcaag aaatgaagcg taaacatatg taggtctgac aataattcta atgggggcat
    11641 aatttaaatc gcttataagg ttccgtatat ataaatcttc tttcaaaata aagtatattc
    11701 ttttgaaacc ttcaataaac tctctttcaa attcaaagca ttctgctaca ttatttttgt
    11761 aaacaggaag gttccttccc cttttaaaga gatattgttt ctttctcata gaaattttat
    11821 ctgtttttat atgaagcact tcttcttttt cacctttttg attttctgta tttatcaagc
    11881 ctcctatatt agtcaaaccg ttatcttccg gaaaactcat atagttaaaa agtgcagatt
    11941 ttaatattgt tttatttacc tgtgctgatg ccattaaatt aacattttcc ttgttctcct
    12001 cagaaaaaaa gaggctgctt tgaaacagag tctcaagatc aaccaacacc ggtttatcac
    12061 gacatgctat gatattttca aaatgaaaat ctgacccttg aaaagcataa ataaatccta
    12121 aatgcattcc aaattggtaa taataatttc ttacctgttc aatattatcg cacggttcag
    12181 cctgtatata ctcttgccac ccgtactcac cttgatccaa ggataaaggt gtttttaaat
    12241 tagtttgata atactgattg acataatcaa tgaccttttc ataaaaaaca tcaatttcca
    12301 gtgaacgggg tttataaacg agtttgttat tttcaaattc aataataaca acacttttac
    12361 cgccattatg aacatcccct gcattcatat taatctttct catttttccg aacgaaagat
    12421 tgaatttttg ttggatgttt ttatagtcat taatccaatg tttaatgata gatatagtga
    12481 agcgtataaa atcagaagtg gatctggaga ttaaatcttg caatacagga taattattga
    12541 gtatttcttc aacaaatgcg gagtttttca gcctttctga gaatatatca taatttttag
    12601 attcattttt ttcatcaaac tcgtcaaaag tttgatgaaa ctcatggata agtgttttcc
    12661 ccgccaaata gtatattttt ttcttataat taattaatat cgattcaaca agacatccct
    12721 tatccagcag actttcggat ggtattctat ctatttcttt aacaatctga gctttaaaaa
    12781 tacttatata atactgcgca aaaccttcga aataatcctc ttctttaaaa atatttaaca
    12841 tagagttttc ataaacatag ttatccgaat tctgtgtttt gttcacattt atcacttcct
    12901 tatatattct tgactgtctt tgacaaaaga aaaagaatat gtacgcatat acatattctt
    12961 tttcggatat gtttagtcgt tacatggact gacaatggac gcacactttg tcgtcggaca
    13021 gcctgctaaa gagattggta ttgtgatggt tgtcggcgtt acggtcatcg gggttgcatc
    13081 tgatccccct gcaaggtttt ttaattcttc ttcagtcatt ggagtcagtg cttgaaaatc
    13141 ttttttcatg ttaattcctc ctattgtttg agttttttat aaatttcagt cgttacatgg
    13201 actgacaata gacgcacatt tagttgtagg acagcctgct aaagagattg gtattgtgat
    13261 agttgtcggt gttacggtca ttggagttgc ttccgatccc cccgccaatt cttttaattc
    13321 ttcctcagtc attagttcca atgctaaaaa ttcttttttc attaaaaatc cccccgattt
    13381 gttttttata cttgcctttg cggacatgcg cagcctactg tgatagttgg acaaatatga
    13441 tttgtgattg gatatgttgt tattgatact gagttttgcc ctccaacaag ctcttttaat
    13501 tcttgttctg atgtttcata caacgcgctg aagttctttt tcatatttca tatctcacct
    13561 cctttcaagt taataagtct gctgcagctg cgattcatat ttggccttaa tggtctttaa
    13621 gtttccattt tcaatctcgt agacagattc ggaaaattcg agccattcgg ttctatgagt
    13681 aatagaaatt acagtgatat cctttttgta aatgttattt aatattttta attctgtatc
    13741 cttatccaaa ttgcttgttc cttcatctat aaaaagaatt tgcggatttt tcgctaatac
    13801 tctggctatt gagattcttt gccgctgtcc acctgataag gtaataccgt tttctccaat
    13861 catggtatga taccccatgg gcatttttat aatatcctca tgaatacatg cttcttttgc
    13921 agcttgtaca acttcttcca ttgttgtttt ttcattgaaa tattttatat tatttataat
    13981 agtgtcatta aacagattga catcttgaac aatataacct aacgtttctc tcagcttaac
    14041 catattaacg tcctctattt tgaattcacc gtagcaaatt tctcctgctg ttttttgata
    14101 aaggccggca atgattttaa tcaaagtaga ctttccgcat ccggtttttc cgattaatgt
    14161 gattttttct ctcggtcgga tcattaaatt tatattattc agaatataat tgtttccatt
    14221 gtagctgaaa tcaatatttt tcaagctgat attatgagcg gccgggttaa atagttcatt
    14281 gcttttatca ttgacttcct catctttttc atccagtaca gcctcaaccc tgtctaccat
    14341 ttcttcaact aatttaatag actctaaact gccgataatt gatcccaacg gagacataaa
    14401 ccgtccggca atgttagaaa aggcaattac cgcgcctagc gtaaggccta tagatgctgc
    14461 tgaccaggta cccacaatta aaataagtaa tggcaaagat agattgattg cattggagac
    14521 cgcacccagt aaggatgaat aattcattct ttttgagaaa taatctagtt gatgattaaa
    14581 gttataattt aattggcttt caatattcct tgtctctcct attgttttta taaacgtcat
    14641 ggatcttaaa atttcaatta gctggctctg aaaatttgat tgactattta cttcctgttt
    14701 tgtgaacatt tcaattttcg gaagtaaaat tttagtactc atcacctgta tacctgctcc
    14761 caataaaact ataaaagcta aaatcgggga ataaacaaac atgactatga aaaatacaaa
    14821 tataagactg atatctaata tcaaagtaga cgctaacctg gaaatgactt cacgaatcac
    14881 agcaatgtta tggattctag ttgaaatatc cccagcggta ttcgcctcaa aaaactttaa
    14941 tggaagactg aatattttat gaattatttt atcagtcata ctcttattaa tttttaattg
    15001 cagtttgata ataaatttca ttctgattaa ggacagacta aagaataata caattgaaac
    15061 aataacaatc ataaaaagca ttggtatggg aagacttttc tcattcccgt caataaatga
    15121 atcaataata tattgagtca aaaaaggggt cattaagttt aatgcttgaa aaataaaagt
    15181 gaaacttata ataaacccca atattttttt atctttcaaa agatattttc cgatctttct
    15241 aaatgaagac acatctttta atgacgaagc agacttatcc tttctctctc gttcgttctt
    15301 tctgattaac ataatagaaa tgccattata gaaggttttg aactcttcta atgtgattgt
    15361 cagtctgccg gacgaagggt ctataatttt aacgctatct gtgccaaatg cgtcgacaac
    15421 tacaaaatga ttatgattcc aatgaacaat tagcggatgg tttttattta actctttaag
    15481 ctgcgttata ttgtctgtgc tgaatgcttt aaattcataa tcgaatgttt cagaaatctt
    15541 tttcatttca attaaatcag tgccgtctct tccgataatt tctttattta attttaattt
    15601 gttaggattg atttttattc cctctgccct gctcaaaacc atggctaaac aagtaatacc
    15661 gcaatcaaat tgatttcttt gaagaataac cggaagtttt ctttttctaa ttttcataaa
    15721 agtctcctaa tgtatccaca catcctattt caagattaag aatattcggc aatttcacgt
    15781 ctgctgcata cagcattcca tatacgattc ccgccaaacc aagcattaaa ttaggcgttt
    15841 caacatccct tcccactccg cattggtaga aacctatatt tttgtcttgt acactttcca
    15901 aaatcaagtt ttttccgata tttacaaatt gactttcgcc agtctttttt ccatactcga
    15961 tcaatattaa agcattcccc atgtccccgt gacaaaggct ttgctctcgg ccaaaaccgt
    16021 cataaaaaat gttagaaacg gctttattca gatctttttt ggcctcttcg gcaatatcag
    16081 ggtgttttga atctttcaat tctaatctgc ttaatagaat tccaggggat ccatggcacc
    16141 atgcagatgt tgcagcttca tttaccggtt ttctcagatc aagccagtta ccgtttactt
    16201 tttttgaatt ttcaaaagca agtccttttc gaatgtacat acttatatct tgatgttttg
    16261 aatgtttctc gagtaattga agggcatata tcattccagc gtttccatga gaaaaacccg
    16321 ttaaaggctt atttgcaata ccttcccaag tgacaagatt cccatcaaga aaggtcgctt
    16381 gtttcattaa gaatgaaccg cattgttcag ccaatgataa aaagaatgta tcattctcta
    16441 tttcaaacga acgtaccatt acaataagag cccccgctgt gcccccgatt atatccaatt
    16501 ctttatcata aggaagcaaa gatggaataa gctgagcgat ttgttttgca tcctgtttat
    16561 atttttcgcg tttagtatac atatagaaat tcattaaagt atatacaatt gaagacactc
    16621 cggaaaaagc acctacagac atagtgctgt cttcgtccgg tttcatctca atatcaataa
    16681 aacgagagat gacatctttc ataatttttt cggctatgtc cagatatttt tcttttttcg
    16741 tgacacgcca taaagccaag taggtaaaag ccatcccgga aagcccgtcg taaaaggtat
    16801 cacccataac agacaagttc cattgaattt catcgactcc aataggagta gcgttaagcc
    16861 aagaatacga acttccttta tctgtgtgtg ctttgtaaga ttgattataa atataagcgg
    16921 ccaattcctc tgctttttct attaagatac tttcttggtt actactgaaa acatttacat
    16981 attgtcctgg ttcttttgtt ataaattctt tcaaaacaat ttgccggtca tcctccgaag
    17041 caagcatgga cagttcgata acatagagct gaaactttaa atcgtctttt gataaattta
    17101 aaattctttc ttttacactt tgagctggtg ttttcggaaa gtaattttca attttcttat
    17161 tttttgagct tagtaagtct ttctcattca atttcacttt gaaataaggt atatcattat
    17221 tgattaaatc gttgaactca tatttaacaa tggattgata ttcatcttct ggctttggtc
    17281 tctcccatat ttttgataag aaaatttctc tatcaataga gttgtgtaaa aatctaggat
    17341 gaaaacttaa ttctaataaa gcagaatact ttattgtcgg ttttgatata aaccgaacat
    17401 atatcttatt ttcgctcttt tctattatgc ggatcagttc cgaagcatgt tttaatatag
    17461 tcatatatgc ttttgaaaaa ccttgcttca gttcttcgac ataatctttt gcatatacaa
    17521 atttattctc aagcataggg tgattattag ctgtatcaat ttcgacatag tctcgtttga
    17581 ccgacatttc tgctgtcttt aaattgataa gctgaggaac tttaatgatc gactttgctt
    17641 tccctttccg gcctattccg ctgatgtcgg ctttgccccc aaagaagaaa ggaagcagtc
    17701 ctaatgctct gacagattca tgaagctgcg tttcagcttt ttcataagcg tccatcccat
    17761 cctttttttt ctggtatgca ggatgaaata aggattccaa atcaatgaga actggatagc
    17821 tcccgttggc aatgagattt tccgaatgaa aatcaacggc tttcaatgca tataacaaac
    17881 cgatttgagc tcctgtacgc tgataaaagt tttgaatatc ttttagacaa ttgcaagctt
    17941 taaaagatat aaattcagtc catccatatc cgtctctgct aagcacattc ggagtactca
    18001 attttatatc atgatctcta attttctcat tcaaaaattc aattatcttt ttatataata
    18061 gatcaatttc taaacttctc ggcttataaa taagcttgcc ttcatttaat gttattttag
    18121 taacctttct accatcagaa tgagaatcac ccattcctac ttcaatatcc cttaatttga
    18181 cttgttctga aaaaccaaat aaagagagca gttcaggctg gtccttttca aaacgcgaga
    18241 taaattccaa tatgaatttt ttaaattttc tcagttcgtt tccgatcact cttaataaga
    18301 ctggatattg ttgaaaaaag cttttaagat actccggact gcacaaaaga gttttattat
    18361 aataaccata tttttcttta ggagtctctc ctgccaaaaa acctttttcc cgattcatat
    18421 tcatatccaa tacaagtgtt ctataggata cttttaaaat aattttttct aattgatttg
    18481 aaatactatg atgaaaaaga gccggttgtt ccagcagata gtcataagaa ggaaactttg
    18541 attttttaag tagatcattg aagtaagagg acacttttaa cgcaaaaacg tgaaacatga
    18601 tttcttcatt tacgtcttct tttttaatag cttggtgagc gatccctttt tttaggtttt
    18661 cgaaaacatg aactgtaaaa gcggatttat gtaggggggt ttgatataag tttttcactt
    18721 tatcaattga ttgaatggat aacacattat gaatgctttc ctgggccatt tgaatatcat
    18781 tcttatagat taattctaag ttttgatcaa acagattctc attttcatca aattgagaga
    18841 cagcagcttt tttttcttta cttaatagaa tattagttag cgaattcatt taatattcat
    18901 ctccttttaa aaaagaggga gacagctgga tctcccagag cattggaaat ctattttctt
    18961 attttcggat ttgttttaac accagcaagt gtgagtagga caaagaccgc attcccaagt
    19021 taacgtacaa agcttaccat catttccttg agaaatcccc cgctgttctg cgcctcctcc
    19081 tccgctgatt tcatttaaag aaatttcctc aagttcttct cttaaatcac cggcaaaacg
    19141 atacattttc tcattcatta atattcctcc ccttgagttt ttgaaatata ttggatttga
    19201 atccatatat ttctataaat ctatgataaa cgatctttta cctataggca ccgaaaagtc
    19261 atattcggaa aagcgctttt tttttgcgcg tttccgaagt ataagttata aagaaaatcg
    19321 ggattaactg ttccgttaat cccgattcac ttactcatat atagttttca tagaaattaa
    19381 tgaatatcga tttgctttga tcagtgcctc tgttctggat tttactccga gcttgttgta
    19441 cacaccagta agaatgtatt caaccgctct ttgactgatc aacagctttg ctgataattc
    19501 ccggtttgtc attccctccg ctacgcccgc taagatatct tgttctcttt catttaaagt
    19561 aatatctctt attctatctt caagcttatc aatgttgaac gtatttgctt ctgttcttct
    19621 taattgttta aagagatgag taggaataat ggtatctccc tcaatgacac tttcaattac
    19681 ttttatcata tgctcttctg ttgaagactt acttatgaac ccggaaacac caacttcaac
    19741 caaaagattg aaatggacag agatatcaaa accagtataa attataattt tttgatcggg
    19801 actctctcta agaatcattt ttgacaattc cattccattt aactccggca tatataaatc
    19861 aagtaaaagt aagtcatact cgtaatgctt aaggtgatta agtacttctt tacagcaaga
    19921 caatattgtt actcccattt tattgcttct ttcaagaatg gcttttgtcc cttgagcaac
    19981 accaatatga tcatcaatta atagaatctt tatcatgtca gcgctcccta ttcatttttc
    20041 gtacttattt caaaccttaa cagcaatcct tcatttacgc ctgaagatat attatgaatt
    20101 ccattcatac aatttatacg ctctttgatc cctgtcagcc caaaactgtt tgtttttgaa
    20161 tttactttat tccaatcaat gccgattcca ttatcttcgt aaacaaacat aagacttgtt
    20221 tgtttttgaa tcatcgtcaa aacaatataa ctggcttttg agtgttttac agcattagta
    20281 agcaattctt gaacaatccg gtaaatgttt attgtgatat cttctgtaaa aatagaatca
    20341 tcttttacat ctacaaagaa ttcaatatca agctgatagt tgcttttatg tttatcaatc
    20401 aggacttgaa tgcttcgcag aagtcccatc tccattaaaa aaggtggtct taaatcaaaa
    20461 catttttctc ttatatactg gatattgccc agcaaaattt ctcttatgta ataaatatcc
    20521 ttgtatttct caacatgata ctctaattct ctgcatacaa atatcagctc ttgaatgata
    20581 gagtcatgaa tatcctgtgc aagcttggtt ctctctattt ctgaaataga aaataaaacc
    20641 ttagaaagta cagccgactt acatttatgt tgattgtcta tgataatttc atcaattttt
    20701 ttttgaatta ataatttgtt ctgaagtgca gatgctgtgc agaatgccag cattcgcagc
    20761 caatctgctt cgttttcacg aatctttata gggtgtcctt tatgtgataa atgaataaaa
    20821 acaaatgtat cacacttctc cccgataaac agaattgatc cgctggcagt ttcacgtatt
    20881 tctcctatct taaaatttga aatgtttatg ttaggaacct gaatgtgatt tcctttcaat
    20941 tttaatgttt ttttgtcata gtttataaga gcaatctgct ttcctgaaaa cacactttgt
    21001 atttcattgg ttagttcttt tatcaattga tctgcatcgg atccctcttg gcataattct
    21061 gaaaaacgga acaggctgcg aagatatgtc ttatttctgt catcataggt aaagcataaa
    21121 caactactgc cgaatatact tagaacaaaa aatagactat actgtttaaa ctgtaattgg
    21181 ctgtctgtta taagcaaaag cataaataac aataataagg agaaaacaaa agcccttgca
    21241 aactgctcca tattaagctt cacccaatta tctttcattt gtatccaagc cccttactaa
    21301 ggaaaataag ggaatccctt tgaatcccct taaaatgaaa aagttacttt acacttatta
    21361 aaatataaac agcaaaggca acaatgtata ccagaaatga tccagtcata aattttacag
    21421 gttttcttga aaagtttagt actcctctta atccgtcatt caaaatcatt ccgaaaaagg
    21481 taaccagtgt aactcctaaa gcgagcattg aaatcacaaa aataacttgc tccatttata
    21541 ctcatcctcc atttacattc tgtttttttt cgaatatacg tataatcctg ataaggacac
    21601 caaaacatac agccccataa tcagtaatcc ccaaactaaa agaattgaat cggaatatcc
    21661 catattactt tcaaaaattt gaatactgaa acgataaata aaagaaaaag gaaagactat
    21721 tgagacatca cttgctaaca gtatcgtcat tattaaaaag gaagctacac cggttatcat
    21781 gacaaccact atatttttac ttaagaaagc aattaaagct gcaatcggaa tggttagcag
    21841 gctcaaagta gtagaagtaa aagatgtcgc tattaatctt aataagtcgc ttgctgagac
    21901 atcttcccga aaaaagaaaa acaaggtgga taagtgaata atatgattaa cagctgaaat
    21961 taaaaacaaa aatagaaaag ctgcagctag ctttgataat atcaatttga atttatgata
    22021 cggatatgac atccaattca gcattgtcct gtttttaaat tctaaataaa aataaaaacc
    22081 tgaaaaaata aaaataacag ttggaaaaag gatcgaatac tgattaaaaa caaacatata
    22141 aaatttgttc caatctgtat tttcgttcat agccaaaaga ccgattccgt ttatgagaaa
    22201 tggcaaaaag cttagaaaga aaataacata aattgatttc agtcttttaa gttttagaaa
    22261 ctcgttacgc actaacagac tcatgacctt tctcctttgc cagcagtttt aaataaagat
    22321 cttccaaaga tagcttaaat ccgtcaatag attccttgtt aaatccacaa gaatttaatt
    22381 tctctttcat ttccgacgga tgaattactg aaataaactc gaattgctgt ttattccttg
    22441 aaataacatg atccgcaaat ttctcaatat ccgcccaatt aatacccgct tcagctggaa
    22501 ttttgtataa ataaagatgt tgcgtatttt tcataaaggc tgactcgaaa ataatctccc
    22561 ccttattcat aataagcaat tcatcggcca tgagattaat ctcacttaaa aggtgacttg
    22621 agataacgac tgtggttcca tttttcatta cttcttggat cagcatttca cgtacttctt
    22681 taataccata tggatctaaa ccgttcgtcg gctcatccag caaaagcaat gcaggagcat
    22741 gcgcaactgc tctggcaatt cccagcctct gtttcattcc taatgaagtt tgcgaaaaca
    22801 gcttatcttt atgttcaaaa agtccaacct ttcctaaaat ctcatttatt tcttcatcag
    22861 aagctgatct ttttaaatag ttaagatgta atttaatatt ctcaaaaaga gtcaaatttt
    22921 cataaaagcc aggaaattct ataatacttc cgatagactg aatcacatca ttatttggat
    22981 tgcgatataa gttatttccc tcaaaaatca cttcacctga agttggagga aatatgccta
    23041 aaagaacttt aagcaatgtc gtttttcctg caccgttggg acctaataaa ccatatattt
    23101 ttcctttttc caatgttaaa tttatatcat gtaaaatttc tttctttttt atagaaacat
    23161 tgataccttt ggatattaaa gctggatcag cctttcccac ttttcatcat tcctttccgt
    23221 cttgttctgt ttataatata aacttacgag gttaaaaaga agatataatc aaggttaatt
    23281 tgcgtttaaa tttctcaaca taaaaaatac gtgaagcctc tacggcttca cgtattcact
    23341 gctgtttgga taaattataa aaatcgttcc gttttgattg ctctttattt tatgttcaag
    23401 ccccatttgt ttaagcatca tattaatgat cgataagcca atcccggcgc cttttctttc
    23461 agatttatta ttcattcccg ggcccctatc ctcaattatg attacgggtt tgttttcaat
    23521 tagctttgtc tgtacggaaa cgtattttcc tgaatgagca tggcgcaaaa cattttgaaa
    23581 aatgttatca agaattctct tcaaccaagt ctcgtctatt tcccatacga tgttttcctt
    23641 cagatcaata tctattgtaa agtgctcttt ctcaaaaatc ggataccaag ctgttaacga
    23701 agaacgtatt atctttaata tgtcacaact ctttttatga agcggcaatt tacctgcggc
    23761 aagaagagaa aatgatgaca aattgtcaat cagttcgccc ataaacgtta ttttatcgtt
    23821 tatgatccct aaagaatgct ttccattttc actgcttatt tcattcttta atgtaaatgt
    23881 atgccctctt ataaccgtaa gaggggtcct taaatcatga gataaatcag caatcaagtt
    23941 ttttcggatt tcgccttctt cgcgctcttt ttgtctgctg ttccttagtt cctcaaccat
    24001 ctggttgaat gaatattcca cttggcccag ttcatccttc tgtttaactg ttacaaattc
    24061 cggtatgccg tcattatctt gttttttcat atgatacccc aaagaaatta accttttttg
    24121 tattttcgca aaaaacatcc atgaattaat cacaaaaagt gaacagacaa aaatcaaggc
    24181 gataaaccat atataggaat acttagccct cataacctcc cattgagatc ctataattga
    24241 gcgcggagtt tctaaaaatg catatccgct gtcttcactc ccatttacat aagcactcag
    24301 caataaatat ttcttttcgt tttgttctat cattttaatc aattcgctaa ggtgaataac
    24361 ctcacccttt ttggccaacc gttctgagtt agaaaacatc acctttccct tatcatttat
    24421 ccatacaata tcagagtgtt tatattgctt catgtgcggg aaagcagacg taatttcccg
    24481 attggatttc cctgaaaaat cttccacatc agacttccaa tcactttcca acttgtttgg
    24541 ttcatagtgt acttgccctt ggtgatcaat caagtatgtt aatgtgacat agtatagaaa
    24601 attcacgcct aaaaaggcta tcggaaaaaa caaaattgag gcaacgatat taataaggta
    24661 tttggttgat aatttcattg tttgatcctg tatccaatcc ctctgattgt ttcaagaatt
    24721 tccggctcat ttggattgat ctcgattttt tgccgtaaat gccggatatg taccatcaac
    24781 gtcttatccc cttcgatata aggctgttcc caaatatttt cataaatttg ttcctttgtt
    24841 aatatttgat tgggatgtct aagtaaaagc aaaaaaatcc ttaactgctt atcagttaaa
    24901 aatatttcct catgactttg atgatttaaa attctttttt ctttcaagtg aacacttaag
    24961 tgttttagct tcaattcatg aatggcagtc ttgtcaaatc ttcttaataa tacttcgatt
    25021 cgagcagcca gttcatcggg atgaaagggc tttgtcacgt aatcatccgc aaatcctaag
    25081 cctttcagct tatcttccag acccgttctg gctgttaaaa gcaagagcgg gatctgcgga
    25141 tgtgtttttt tcatcctttg accgattgta aatccgtcta aaccgggcat cattatatca
    25201 agcacgatca gatcagcctt ttctatatat gtttcgtaat tataggaaga agtgagccat
    25261 ataatcatat agccccgatc ttctaaatca ccttttacaa attggccaat ttcttggtca
    25321 tcttcaatgt ataaaatgtt attcattagg accccctctg aaatatgtga ctgaaaatca
    25381 atcttccata ataattatat atattataaa aatctccttt atgtaaggca ccattccatt
    25441 attataactt atagatattc acaattcatc aaggggcaaa acgataagtc aactcgaaaa
    25501 ggcggtctgt tgtcagatcg ccttttccct tataatgtca caccggactt aaaaattgca
    25561 agctcccgaa aatcgttttt ttcgttattg acgaattctc cgcttgcaac tttaataatg
    25621 tattgaataa aatctcttac aatgtgatct tctgttgttt ggtcttccgc caatctgccc
    25681 gcgttgtaat caatccaatg aggctttgat tgaaataaat cggtatttgt tgatactttc
    25741 acagtcggga caaatgtgcc gaacggcgtg cctcttccgg ttgtaaacaa aacgatgtga
    25801 cagcccgccg cggcgagcgc tgaagaagcg attaaatcat tgccgggcgc actgagcagt
    25861 gtcaatccct ttgttttcag tgtttcaccg tatgtcagca catcagaaac cggtgcaaga
    25921 ccggcttttt gggtgcagcc gagcgacttg tcttcgagcg ttgaaatgcc gccttcctta
    25981 ttccctggtg acgggttttc ataaatcggc tgctcgtgct tcataaaata ttgcttgaaa
    26041 tcattgatca atcggactgt tttatgaaac acttcttcac tcgccgcacg ctgcatgaga
    26101 atcgtctcag cgccgaacat ctcaggcacc tccgttaaga ccgtgctccc tccctgtgca
    26161 atcaagtaat ctgaaaatct ccctaataaa gggtttgcgg tgatgccgga aaaaccgtcc
    26221 gacccgccgc atttcaatcc gatgctcaat tctgacagcg gaatctcctc acgtttatct
    26281 ccctttgccg caaggtgtat ctctttaaga agcgcagtac ccgcttcaat ttcatctgtg
    26341 acagcttgtg attcgagaaa tttcacccga tctccattca cttcagaaag cgtttcctta
    26401 atcgccgcaa gctcattatt ttcacagccg agccctaaaa ccagcacacc gccagcattt
    26461 ggatgacgga tggcgttcat cagcatttgt ttcgtattct catgatcatc gccaagctgg
    26521 gagcagccgt attggtgctt taaaaccagc acattgtcaa agggcgcaat gtctttcgcc
    26581 tcttttacga agcgctgcag gattttctca gcgacgccgt ttacgcagcc gactgtaggc
    26641 acgatccaca gttcattccg gacgccggat gtaccatttt ctcttctgta gcctttaaat
    26701 gtccggttct catttgtaaa aggattgtcc tcgaagcgcg gtgaatacgt gtattcttgc
    26761 acatcggata aatttgtttg cagattatgg gtatgaatat gctcgccggc cgaaatccgc
    26821 cttgtcgcac gcccgattga aaaaccgtat ttaatgatgc tgccgttttc ttcaatggtt
    26881 tgcagcgcga ttttatgccc ccgctttaca ggatccttca cttcaatcgt cagtccgtct
    26941 gtatgcagcc gctccccttt gttaaaatgg cgcatggcga gaagcacgtt atcgttttta
    27001 tggattttta tgacctcttt catttcactt cccccttttt tccgcagcat tcatgtaacg
    27061 catgcttcat accccgctta tgaatgacag acagaaaaaa agccgttcgt tcagtcagcc
    27121 ccggaagatg attcagattc tccccccaca atcgctcttc tcctaatatg gcagatgccg
    27181 cttgaaacat atcatctttg caacgggacc gcgccatttg aaaacggtta agaacctcct
    27241 cgccgtctgc cggtttgttc ggtccgttcc agtatgaata gatcatggcg ctgaacgaaa
    27301 ataccagctt ctcaggtagc cggccctcct gttcgatata agccttcagc gtcggcaggt
    27361 ttcttgtttt gaatttcgcg gcggcgttaa gggtaatgct ttgcagataa tggtaaatat
    27421 aagggttttt aaaccgctgt aacacatctg ccgcgtattg gatgacaccc tccatttgca
    27481 gcacagggag gatttcttca ttgatcagct cttcaatgaa tctgcccgtc acctcgtgct
    27541 cagccgcttc ccggacggtt tgcagtccgt atagtaaagc cactggcgcc aatgccgtgt
    27601 gagcgccgtt taagattctc accttttttg tcctgtaaga cgtaaggtca gacgtgatca
    27661 gtgcgttcag cccggcctca gcaaaaggaa gctcattctg aagctgttcc ggcccttcta
    27721 tcacccacaa ataataatgc tcaccaacca caagcagacg gtcttcgtat ccgagaaaat
    27781 cggtaagttc ttccgcggta tcaacaggaa atccgggaac aatccgatcc acgagggtat
    27841 tgcagaagat gttcgcgtca tgaatccatt gagtaaaacc aggttccagc tcccacagcc
    27901 cggcatattg aagcacggcc gccttcagtt tccgtccgtt ttcttcgacc agttcacatg
    27961 gaagcataat gcaccctttc tcggcgtcac ccgcaaatgc cttatagcgg aaataaagga
    28021 acgccgctaa tttcccgggg aatgtttttt gaggtctatc ctcaagccgg tcgcctttct
    28081 caaacgtgat tcccgcttcc gtcgtattag aaatgataaa acgaagatcc tcttgtgctg
    28141 ccagccgttt aaaggaatca tagtcagaaa aaagatcaat gccgcggctg atggatttga
    28201 cgatcatgtg ttcttcagcc ggttttccat cctttatccc ctgcaaaaaa agcgtaaata
    28261 aaccgtcctg ctcgtttaaa cgtttgattt tctcagagcc tctcggctgt acggcgacaa
    28321 cgcttccgtt aaaatccgtc aattgattca attgatcgat ctgccagtca gcgaaagccc
    28381 gcaaaaagtt gccttcaccg aactgaagga ctttttcagg atattgaatg tattcgccgc
    28441 acatcttttt attcagctgc tgcaagctgt ccgcctcctt ctgtatttat gcacacgtta
    28501 acatttctcc gtgtgaaaac ccggatattc agacgggccg ttatgtgagt tttttaatgg
    28561 aatctcttat gatcacctcg gtgttttcat atattttttc cgccgccgta tccgggtcgg
    28621 cgattagcgc caaaatcttc tctgcgccga gtatgctgat gttttcaacc gggcgtttta
    28681 ctgtcgaaag cctcggcgtc atgtattggg aaatgccgat gtcatcaaac ccgataacgg
    28741 atatatcttc cggaacgttc aggcctttgg cgaaaatggc gttcatcgcc ccgatcgcca
    28801 tatcatcgtt tgaacaaaaa acagccgtag gaggtgattg aagcgccaag agtttttcca
    28861 tcgcctgact gccgctttcc atatcatag
//
