LOCUS       NZ_ML123034            22745 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6649602
            Orig. end                         :: 6672347
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..22745
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="30"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22745
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22745
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12745](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12745)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(26..577)
                     /locus_tag="EES43_RS29070"
                     /old_locus_tag="EES43_28730"
     CDS             complement(26..577)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF021886.4"
                     /locus_tag="EES43_RS29070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28730"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_124271536.1"
                     /transl_table=11
                     /translation="MSLRIALLGTLAHQGPASGYELAKHFDTSVNLVWQARHSQIYPEL
                     AKMAQSGAVTVEDAGGGRGRKVYTVTDAGRDEIARWVTAEDPYRSVRNESGLRAFLVTL
                     IPPDEAAAVMRAQEARHGAALDALLKVKDDVAARTAPGSPPFGAYALDLGLRTTRMLQE
                     WAADTAEQLEKRAAASEQTP"
     misc_feature    606..615
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     misc_feature    609..624
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     gene            633..2078
                     /locus_tag="EES43_RS29075"
                     /old_locus_tag="EES43_28735"
     CDS             633..2078
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:TIGR00711.1"
                     /locus_tag="EES43_RS29075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28735"
                     /product="MDR family MFS transporter"
                     /protein_id="WP_206430146.1"
                     /transl_table=11
                     /translation="MKREPRTNNGLLLIAILGGMFLAMLDQTIVGTALPRIVEDLGGES
                     LYTWTVTAYLLTATVTVPLYGRLSDLYGRKPLLVTGIVVFLTGSVLCALSQNMGELIAF
                     RAVQGLGAGALLPLSLAMVADTVPPERRGRAQGAVGAVMALSYVVGPYLGGVFTDQASW
                     HWVFLVNVPIGVLVLAIIWRRLPGGGGVPNAGRPDYAGIGVLTVGISSLLVGLTMKGVD
                     DNTWTDAAVIGPIVLALALLVPFVAIEKRVAQPIMPMGLFRNRAYTLANVASFFSAFSL
                     FAAVVFLPRYFQEALGHSASTSGLLLYPLMIAMVAGSLVAGILISGSGRYKPCLLGAAV
                     LAAAGSALFTQLGLGTSLPAMSIWMLLIGLGIGPTLSGLTLVTQSAVEPGDIGTASSNI
                     TFFRQIGGSVALAIAGSLYADTLTADMSGGLHEAQAAATAAALPWLSAIGAVATFVAVA
                     FLPAPRRSLRQEASTDAPLSSPV"
     gene            2178..3587
                     /locus_tag="EES43_RS29080"
                     /old_locus_tag="EES43_28740"
     CDS             2178..3587
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014179979.1"
                     /locus_tag="EES43_RS29080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28740"
                     /product="carotenoid oxygenase family protein"
                     /protein_id="WP_124271537.1"
                     /transl_table=11
                     /translation="MTTSEDRTGPDTPPYLLGHYAPVPDEFDAVELTVTGALPPELDGR
                     YLRNGPNSRPGEDPGHLFTGHGMLHGVRLRDGRAEWYRNRWVRTTRLAGAPYNRPDGTL
                     DLAAVNANTHVIAHADRLLALVENGLPYEVTGELDTIGPCDFGGRLTTAMTAHPKQDPV
                     TGELLFFGYSARPPHLVYHRLSASGELVESRDVSVPAGTMMHDFAITENYVVWLDLPVV
                     FDLRLAGGGGMPMRWDDGYGARLGLMRRDGTGDVRWFDIEPCYVFHVGNAHEDEAGRVV
                     LDAVRYSRSAFTAMWQTMGGPVGSPVADTGWVLGETQGGNVHRWRLDPATGRVDERPID
                     DRGVEMPTINDDLTGRPSRYLYTVAERAIIKYDTLSGASHAYGTGDGSSPGEAVFVPAR
                     TATAGEEDAGWLLTMVSHGPTQGSELLVLDARDLTRVAAVEMPRRVPAGVHGSWIPERG
                     PDAAGERPSQD"
     gene            complement(3712..4389)
                     /locus_tag="EES43_RS29085"
                     /old_locus_tag="EES43_28745"
     CDS             complement(3712..4389)
                     /GO_function="GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959209.1"
                     /locus_tag="EES43_RS29085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28745"
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="WP_124271538.1"
                     /transl_table=11
                     /translation="MSPSAPAPRYTVPGLDTDEGRRVIDLLSLRLHALNDLSLTLKHIH
                     WNVVGPHFIAVHEMLDPQTAAVRDMADAAAERISALGGEPHGTPGALVAERTWDDYSVG
                     RADAIAHLGALDLVYTGVIEDHRQALAEVSEIDPVTEDLLIEHLRGLEQFQWFVRAHLE
                     SSAGTLANAGADTEKQAARAAAPQSATAKRTPAKKTAVPASAKKTAAKRGAKKTTASKR
                     VTR"
     misc_feature    4582..4595
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.51"
                     /tool="antismash"
     gene            4886..5977
                     /locus_tag="EES43_RS29090"
                     /old_locus_tag="EES43_28750"
     CDS             4886..5977
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962349.1"
                     /locus_tag="EES43_RS29090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28750"
                     /product="response regulator"
                     /protein_id="WP_206430147.1"
                     /transl_table=11
                     /translation="MGELRPLGQDLTNESRALAEALRELFAGLDVSVRRYAARRRRDPG
                     TFSRYLNGTRLPPWGVIMDMLADLAEHRGTTVTAETIELVRELYGSAFDANSSPKHAVQ
                     IIEQQLADADHVSRRSSVRGDVLGDALLDRKHRIAHLEVRLNQMEAVLAAERERADQLT
                     AAHPDVSELLGERDLLRQEVTRLGNELQEAREQRADAEARCDLLERQLEVVERPAALNL
                     PQPQPLTTPKVLVVDDQPDNLLAMTAVLGTLDQELVTVSSGRDALKALLHHDDFAVIIM
                     DVQMPEMDGYETAAHIKRRPRNRDVPIIFLTAMGVDPEHTARGYAAGAVDYISKPFDPW
                     ALRAKVAVFTEIHLERRIANSGP"
     misc_feature    5051..5053
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6003..6380)
                     /locus_tag="EES43_RS29095"
                     /old_locus_tag="EES43_28755"
     CDS             complement(6003..6380)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="EES43_RS29095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28755"
                     /product="VOC family protein"
                     /protein_id="WP_124271539.1"
                     /transl_table=11
                     /translation="MNRPRLKHLALVVQDAAAAAAFYRDTLQMEEFHQDPDGSRFVTDG
                     YINLALIQQRLDGDVPAGFNHFGFEVSDVASVADRITDRGVARPVLRGGDRPFAEYRAT
                     DPEGNWFDLSEHGFLPPDAAE"
     gene            complement(6377..6763)
                     /locus_tag="EES43_RS29100"
                     /old_locus_tag="EES43_28760"
     CDS             complement(6377..6763)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02246.1"
                     /locus_tag="EES43_RS29100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28760"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_164493307.1"
                     /transl_table=11
                     /translation="MTDSDGVLALWRAMAEGWRRGDAEAFGAVFAEDVDFVTVRGEELR
                     GREAVVAGHARLFAGPFRDTRLVPEIRLVRPLAGGLRLVHVVTVIEPGGLTTHAQAVVA
                     DDGTGARITAFHNMTVPETRGEQT"
     gene            complement(6756..7445)
                     /locus_tag="EES43_RS29105"
                     /old_locus_tag="EES43_28765"
     CDS             complement(6756..7445)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337286.1"
                     /locus_tag="EES43_RS29105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28765"
                     /product="hypothetical protein"
                     /protein_id="WP_206430148.1"
                     /transl_table=11
                     /translation="MPAFGVPESEQVGYVLTHTRNESEDAVRAPDASSVLFSESALDRF
                     LAAAVREYANITENDPVPCFAVLLGTAADGDWLVHDVAFGRNARTTDPNARQEFAATIV
                     PRFGAAYENPVRAWWLDPADLLRIAREADRRNLDILGSVHMHPDWHRLGPRQARAHPLD
                     ECPTEMDRYVFRSSGWPVNVVCYVERRHGAHGYALSAWDAECRRLALRVHRPATGGVLP
                     GDGGRDD"
     gene            7601..8563
                     /locus_tag="EES43_RS29110"
                     /old_locus_tag="EES43_28770"
     CDS             7601..8563
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="EES43_RS29110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28770"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_164493308.1"
                     /transl_table=11
                     /translation="MRLDVRHLDLVLTIAEAGSLRRAAARLHLTQPAVTTQLKRIEQHL
                     GGELFVRLPDGVLPTRAGSLFVRDATRIRRDLDGLTRTARRALQGDAEAPVRVGGVPAQ
                     HFSLLIKALGTVLPERGATSRTVRSTATATALLASGELDVAVLRRFPDSPLALPPGVAH
                     RTLLTEPIFVGVSLDHRLSGAGRIALGELADEDWVMPPPDDSGMNGHMADTCRRTGFEQ
                     RVAHVTDESHVAFALTAAGDAVCPLYPLGSARESLATLTLTGDPLFRDLVLAWRTDSPA
                     APAVDALCAHIAQGYLALVETDDVYAQWWRRGGAEFALP"
     gene            8583..9119
                     /locus_tag="EES43_RS29115"
                     /old_locus_tag="EES43_28775"
     CDS             8583..9119
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979699.1"
                     /locus_tag="EES43_RS29115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28775"
                     /product="VOC family protein"
                     /protein_id="WP_124271542.1"
                     /transl_table=11
                     /translation="MPVRGINHAVLWVRDADASARFYTEVLGFGVVGESGEAPRKAIFL
                     RAPESDNDHDLGLFGIGAEAAETRAGRGETGLYHIAWEVPTLHDLRAVAERLAERGALV
                     GATDHGTTKGVYAKDVDGLEFEVCWLVPHELIDDEARARRGPLDIDAEIARFGATTEGA
                     CARSARGASPAPSAG"
     gene            9276..9881
                     /locus_tag="EES43_RS29120"
                     /old_locus_tag="EES43_28780"
     CDS             9276..9881
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970264.1"
                     /locus_tag="EES43_RS29120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28780"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_124271543.1"
                     /transl_table=11
                     /translation="MSRAKELFIIAVDPGPEQAVGQGDLSLALAGAELIDLVEAEVVTV
                     DGDRIVPGGRATPGDRLLGEAAEGLIRQPPYERIEDWLWRRGRDLSAAYRAALEEDGEL
                     TRKRSGRRPFGSERVEPVDTPTRRRAAERWEAKEPVLADLASAVGVDAGRSDDEPGFDD
                     DAVTTVLAAVHDAVMELEAVRQRRTIENAAFANLWRGP"
     misc_feature    9300..9314
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(10001..12745)
                     /gene="lanL"
                     /locus_tag="EES43_RS29125"
     CDS             complement(10001..12745)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964025.1"
                     /locus_tag="EES43_RS29125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_241192571.1"
                     /sec_met_domain="Pkinase (E-value: 6.8e-13, bitscore: 47.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.2e-18, bitscore:
                     63.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGTAPADADGPEARVSAAYRAGPSPSLGPGSPDAGCEGPDGGR
                     ALEDRLTSLLAGRERRVVADGPWLCLFAAGLTNELPQHGWKLHVSARADDLSQVVDLVV
                     PVLLRYACSAKFARGAEVLRAMNSGVRDPALVGKAVTVYPRPDDVTALGGELARLLAGR
                     PGPRVLSDRRIRPDSPVSYRYGPFRAAGSDDAALVMTGPGGARFPGRAGTRFRPPPWAA
                     DPFRPPAPPGDRPARLIGGRYRITSGIARSPHGDVYRAVDGVTGEQVIVKQARAYTGED
                     ADGLDARGRLRHEHAVLDALSGLDGVPRLRDHLRHGDDEFLVITDCGPGDLCRDVLGRG
                     PYEADAPGPPAGPAPGGGTASRRGVTALADRLITLLDGVHARGVVVGDLKPSNIVLDAD
                     GVAHLVDFGVSALHGDRPVGATPGYSLPVYRAGRRPDPSDDLYALGATLHFALTGMEPV
                     VVDAVAAVNRDRTLACLTAVLPGSAHRPTRELVAGLLDLRPERRAACARRWRDRARLPA
                     AAGRRLPSPPRVGRALLDELIGHTAASCAARAADLPVRPRSPHDRPGFGLTLYDGAAGV
                     GLELLHHTDRPGVSEAVAALARRTAGHPALPRLSAALHVGRTGVDLFLDSAAALTGTPA
                     ASVPAAHLRPYDDTGDQIGGAAGAGTGLLALARRAYAAGRVEEGDARLAAARECVGSLL
                     AAESGRERAEPQQSAAASEAAFTFGFAHGLAGVVHFLHAYHRFTGGPSAGNAARRGLAV
                     LVSHTPRLLELASRPEAHRRYGSWCRGLAGVGTVLIEAGGHEGDGRMTDLGVRCARTCR
                     DLAPRMSPVSQCCGLAGVGELLVDAAAATGDGLLLRGAEDVAGLILARSGGTRRRPLIP
                     DNTLSASGPGWATGGAGVLSFFRRLRDHGGPRLWTDGRAGRGD"
     gene            complement(12759..12920)
                     /locus_tag="EES43_RS30895"
                     /old_locus_tag="EES43_28790"
     CDS             complement(12759..12920)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964026.1"
                     /locus_tag="EES43_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28790"
                     /product="SflA family class IV lanthipeptide"
                     /protein_id="WP_164493309.1"
                     /transl_table=11
                     /translation="MSPLVLQIRDAGPLDVAVEEEDIAFEDQADPSRRVEACLPDPFPT
                     ATTRFGCD"
     misc_feature    12920..12934
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.49"
                     /tool="antismash"
     gene            13240..13992
                     /locus_tag="EES43_RS29130"
                     /old_locus_tag="EES43_28795"
     CDS             13240..13992
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964244.1"
                     /locus_tag="EES43_RS29130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28795"
                     /product="hypothetical protein"
                     /protein_id="WP_164493310.1"
                     /transl_table=11
                     /translation="MHVTRRLTAMAAAAAAITLALVTPAAAAPAPAPAAPAPAPAAPAP
                     APAAPAATASAVGPVQLPIGGLGSGPYNVAVQSAVGTARDNAVARGFDPARCTLVKGPT
                     IVNQLPNGYVQVAVEYLCAGDPYASGPTFVLNRYHKSSDTQSNSWYAPAGYQLQGPLGS
                     LYTYAAPDTTPLYLCQVRGDHFTSTDVNCEGQQYVTRLGWLYTSPPAGVGTVQLLRCLR
                     NENRQIFDSIQPNCEGQIHGGVLGYTLA"
     misc_feature    14318..14333
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            14581..15276
                     /locus_tag="EES43_RS29135"
                     /old_locus_tag="EES43_28800"
     CDS             14581..15276
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358779.1"
                     /locus_tag="EES43_RS29135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28800"
                     /product="thymidylate kinase"
                     /protein_id="WP_124271544.1"
                     /transl_table=11
                     /translation="MIVSLVGSDGAGKSTVSRIAAERMSAAGAGIERVDRWDIIGSPAY
                     PATRFLGSDVRDTRLCVAEMPNTSRFLFLMWSMSHALLGRGPESVRPDRITLLDGYWMK
                     HAAGEIVYGLDSAWVESVVAGLPVSEQVVYLRLDPKDAWERKVGRDVVPYECGMDPDCS
                     QDSFLTHQGRILDVLDGWAGQRGWQIVDAAAPLDDVVDQVVSTVTAASAVSTRSAVAAA
                     SAQAAPPQR"
     gene            15609..17831
                     /locus_tag="EES43_RS29140"
                     /old_locus_tag="EES43_28805"
     CDS             15609..17831
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359138.1"
                     /locus_tag="EES43_RS29140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28805"
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="WP_124271545.1"
                     /transl_table=11
                     /translation="MSSTRLAIVGGGPSCTYVMDRLAAAATAAAGPLSLDVHVFDRAGL
                     FGAGQVHSPEQPVTSVLNRIAGQVAFAADESVVDAGPLLPREDRPTLHAWCRARYEETG
                     DPVFDLAAEDSPKRYVHGLALADRFRRYAAILGDVAGVRVHLHEREVTDLEELPDGRLG
                     VVAGGERVLEADDVLLLTGHSSNDPARYPRQAEWQRFARSHRTGFVPSVYPLDKAFAPG
                     EAGPGTTVGCAGMGLTGIDVILHLTEGRGGVFVEQPDGTLAYRASGREPDSVVMFSGSG
                     LFTFTRPFNAKERDTGKLEHRGVFLTEDAVLRLRRSVGRPVTIGDRPQRQLDFRAHVFP
                     LVVLEMAHVYHTTLLGGAFGDRTAAAVRPVYEAFLADGGGGASSEASVRRLLAPLEAEV
                     DRAAETIDAILSGGLALAEARERDGDVEAALRRFLEVVFGPERAGAVAALSGDPAEFAD
                     AVAAADSPWRHPKSVAGQRFSWERQIRPIDRDASATPARYRAAMLDFLDLDHRWAVQGN
                     LANPAKAAADGVWRDLRNVLAAAVDFGGVNAASHRDFLDVFMRHLNRFVNGSALRPMEK
                     IRALVRHGIVDVSAGPGAEVATDEESGRFVVRGITGAVLPLDILVDGRVHPFDAANDVL
                     PLYPNLLGRGLVRTWRNPGVGEPDFAPGGLDLTEEFHPVRADGEVDRRITVLGWPSEGV
                     MFFQYGALRPDQNHHLMRDILCWMREFWGDRGPASESGGSLAAVRA"
     gene            17859..18191
                     /locus_tag="EES43_RS29145"
                     /old_locus_tag="EES43_28810"
     CDS             17859..18191
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018846834.1"
                     /locus_tag="EES43_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28810"
                     /product="MazG-like family protein"
                     /protein_id="WP_124271546.1"
                     /transl_table=11
                     /translation="MEDTTWPRVERLRHWLDANAGPEATGDVRLWRVLKISEEVGEVAE
                     AMHGATGANPRKGASHTWDDVHTELCDVIVSSMIALTTCTPDAARLLDERLQHLVDRVM
                     PPRAAR"
     misc_feature    complement(18319..18334)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            18413..19027
                     /locus_tag="EES43_RS29150"
                     /old_locus_tag="EES43_28815"
     CDS             18413..19027
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523571.1"
                     /locus_tag="EES43_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28815"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_124271547.1"
                     /transl_table=11
                     /translation="MSDASDAVSGKDMNIEAMVATVGLQIKVLRKLAGLTLDELSRRSS
                     VSTGLISQVERGKGNPSFATLVQIAHGLEVPVGRLFHLAEQISPVVRRDERRTLDFHNT
                     GSGEPDDARYELLTPSLNSALEVIWVETQPGHDTSSTPFRHSGEEFGIVLSGVKDVYLD
                     GVRHRLHAGDSITYSCSIPHWYANSGDEPVTSIWVITPPTW"
     gene            19133..20419
                     /locus_tag="EES43_RS29155"
                     /old_locus_tag="EES43_28820"
     CDS             19133..20419
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523570.1"
                     /locus_tag="EES43_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28820"
                     /product="MFS transporter"
                     /protein_id="WP_124271548.1"
                     /transl_table=11
                     /translation="MASLTDRSPASPGAPSPRRTLFALGGGNAVEWYDWMVYGLLASYL
                     GPQFFPSTNPLSATLSALAVFAVGFAARPVGALVFGTLADRVGRRRIMLLSIGGMVVST
                     AVIAVLPTHDSIGVWAGVILVACRIVQGISTGIEAPLNSAYVVEMAPEGRTARYGGIIS
                     VYVQSGIIAASLVAFVTSTVLGATAMEEWGWRIPFAVGAVGGAVFLRLRRSLPETLHTS
                     GEAPAASRVWADVGRNKLALLAIVFVVAGAQALNYTWSTGLPNLARTVHGENPSAVFAV
                     STLSGLCVAALYPLVGRLADRKRISRTFLVARLAAVPLVFAVLLYQAPGMVLFTVVMMI
                     GAPVLAFTMGLYTTVSATLMPMSCRVTGVGIGYAVGVAGFGGTAPYILLWLQDIGLFWV
                     FPVYVAVLCLLSALFYTLAFRRGSVRVGG"
     gene            20431..21810
                     /locus_tag="EES43_RS29160"
                     /old_locus_tag="EES43_28825"
     CDS             20431..21810
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523569.1"
                     /locus_tag="EES43_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_28825"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_124271549.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.8e-07, bitscore:
                     26.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPNPEKFSAETIPLDAVEAPVVQRSDVIVVGGGPAGVSAAVSAA
                     RSGATVTLLERYAALGGLASGGMVLVLDDMVNGDEITVTGVVDEYVERLTALGLAVHPP
                     AEERVSSPQMWAKWGRWGAYDFHSRLSPKPICYAVAFDPDGWKRVSNDLVRESGVNLRL
                     HSWFSRPIVQDGEIRGVVCETKSGPQAVMGSVVVDTTGDIDVASRAGAAHTQDSYLTTL
                     VFRLGGVDTDEAERFEQAHPREVRAINRKIKRMLGGAWELWWLKTPIPGVVWCNCPHLT
                     GFDGTDPASLTEAEFEARARIAAVLDTIRQDLPGFSGTYLLDVAEQMGVRQTRLLQGEY
                     VMTKDDITSRRHFTDSVARGRDYYYPYRSLLPRGVEQLVVAGRHYSATPEAQRMSREIP
                     PCMAMGQAAGIAAAAAVEQGVRVRDVDPAVIQRRMRDQGADPGDVPAANATTDQSQEVP
                     A"
     misc_feature    complement(22117..22131)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.61"
                     /tool="antismash"
     misc_feature    complement(22507..22522)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.16"
                     /tool="antismash"
ORIGIN
        1 ggccgcccgg ggcgagcgga cctcctcagg gcgtctgctc ggaggccgcg gcacgctttt
       61 cgagttgctc ggccgtgtcc gccgcccact cctggagcat ccgggtggtc cgcagtccca
      121 gatccagcgc gtaggccccg aacggtggac tgcccggcgc cgtacgggcc gccacgtcgt
      181 ccttgacctt cagcagggcg tccagagcgg cgccgtgccg cgcctcctgg gctcgcatca
      241 cggccgccgc ttcgtccggc gggatcaggg tcacgaggaa ggcgcgcagg ccggactcgt
      301 tgcgcacgct gcgatagggg tcctccgcgg tgacccaccg ggcgatctcg tcccgcccgg
      361 cgtcggtgac ggtgtagacc ttgcggcccc gcccgccgcc cgcgtcctcc acggtgacgg
      421 cgccgctctg cgccatcttc gccagctccg gatagatctg gctgtgcctg gcctgccaca
      481 cgaggttgac cgaggtgtcg aagtgcttgg ccagttcgta tccggaggcc gggccttgat
      541 gggcgagcgt tccgagcagg gcgatgcgaa gggacatgcg tacaccatac ttcgggattg
      601 acgtgtaagt tttgacatgt aaggtctgac acgtgaaacg agaaccccgc accaacaacg
      661 gcctcctcct gatcgccatc ctcggcggca tgttcctcgc gatgctcgac cagacgatcg
      721 tcggcaccgc cctgccccgg atcgtcgagg acctcggcgg cgagagcctc tacacctgga
      781 ccgtgacggc ctacctgctc accgcgaccg tcaccgtccc gctctacggc cgcctctccg
      841 acctctacgg tcgcaagccc ctgctggtca cgggcatcgt ggtgttcctg acgggcagtg
      901 tcctgtgcgc gctgtcgcag aacatgggcg agctcatcgc cttccgcgcc gtccaggggc
      961 tgggggccgg ggcgctgctg cccctgtcgc tggccatggt ggccgacacc gtcccgccgg
     1021 agcggcgcgg tcgggcccag ggggcggtcg gcgccgtcat ggcgctgagc tacgtggtcg
     1081 gcccctacct gggcggggtg ttcaccgacc aggccagctg gcactgggtc ttcctggtca
     1141 acgtcccgat cggcgtcctc gtcctggcca tcatctggag gcgcctgccc ggaggcggcg
     1201 gcgtcccgaa cgccggccgg cccgactacg ccggcatcgg cgtgctgacc gtcggcatca
     1261 gctccctcct ggtcggcctg accatgaagg gcgtcgacga caacacctgg accgacgccg
     1321 cggtcatcgg ccccatcgtc ctcgcgctcg cgctcctggt tccgttcgtc gccatcgaga
     1381 agcgggtggc ccaaccgatc atgccgatgg gcctgttccg caaccgcgcg tacaccctgg
     1441 ccaacgtcgc ctcgttcttc tcggcgttca gcctcttcgc tgccgtggtg ttccttcccc
     1501 gctacttcca ggaagcgctg ggccacagtg ccagcaccag cggcctgctc ctgtatccgc
     1561 tgatgatcgc catggtggcg ggcagcctcg tcgccggaat cctgataagc ggctcggggc
     1621 gctacaagcc ctgcctgctg ggcgcggccg tcctggccgc cgccggctcc gcgctgttca
     1681 cccagctcgg cctgggaacc tcgctgccgg cgatgtcgat ctggatgctg ctcatcggcc
     1741 tcggcatcgg ccccacactc tccggtctga ccctcgtcac ccagtccgcc gtggaacccg
     1801 gcgacatcgg gaccgccagc tccaacatca ccttcttccg ccagatcggc ggctcggtgg
     1861 ccctggccat cgccgggtcc ctgtacgccg acacgctcac cgctgacatg agtggcggac
     1921 tgcacgaggc gcaggccgcc gcgaccgccg ccgccctgcc ctggctgtcc gccatcggcg
     1981 cggtcgccac cttcgtcgcc gtggcgttcc tgcccgctcc ccggcggagc ctgcggcagg
     2041 aggcgtccac cgacgccccg ctgagttcac cggtctgacc ggaatcccgg ccgcgcaccg
     2101 ccttccccga cctgacgccc cccgcagcca accccacccc gcgccgaccg gctcggcgcc
     2161 gggagcaagg agtcacgatg acaacgtccg aggaccgtac cggaccggac acaccgccgt
     2221 acctgctggg ccactacgcc ccggtgcccg acgagttcga cgccgtcgag ctgacggtca
     2281 ccggtgccct cccgccggaa ctcgacggcc gctatctgcg caacgggccc aactcccgcc
     2341 ccggcgagga cccgggccac ctcttcaccg gccacggcat gctgcacggc gtccgcctcc
     2401 gcgacgggcg cgccgagtgg taccgcaacc gctgggtgcg caccaccagg ctcgccggcg
     2461 cgccgtacaa ccggccggac ggaaccctcg acctcgcggc ggtgaacgcc aacacccatg
     2521 tcatcgccca cgccgacagg cttctcgccc tcgtcgagaa cggcctgccc tacgaggtca
     2581 ccggagagct ggacaccatc ggcccctgcg acttcggcgg acggctcacc accgcgatga
     2641 ccgcccaccc caagcaggac cccgtcaccg gcgaactcct cttcttcggc tacagcgcgc
     2701 gccctcccca cctcgtctac caccggttgt ccgcgtccgg cgagctggtg gagagccggg
     2761 acgtctccgt cccggcgggc acgatgatgc acgacttcgc catcaccgag aactacgtgg
     2821 tctggctgga cctgcccgtc gtcttcgacc tccgcctcgc gggcggcggc ggcatgccga
     2881 tgcgctggga cgacggctac ggagcccggc tcgggctcat gcgccgcgac ggcacgggcg
     2941 acgtccgctg gttcgacatc gagccctgct acgtcttcca cgtcggcaac gcccatgagg
     3001 acgaggccgg gcgcgtcgtc ctcgacgcgg tgcgctactc ccgctcggcc ttcaccgcca
     3061 tgtggcagac gatgggcggc cccgtcggca gcccggtcgc cgacacgggg tgggtgctgg
     3121 gggagacgca gggcgggaac gtgcaccgtt ggcggctcga cccggccacg ggccgggtcg
     3181 acgagcggcc catcgacgac cggggcgtgg agatgccgac catcaacgac gacctgaccg
     3241 gccggcccag ccggtatctg tacacggtcg ccgaacgcgc gatcatcaag tacgacacgc
     3301 tctcgggcgc gtcgcacgcc tacggcaccg gggacggctc ctcgcccggc gaagccgtct
     3361 tcgtgcccgc ccggaccgcg accgccggcg aggaggacgc gggctggctc ctgaccatgg
     3421 tctcccacgg tcctacgcag gggtcggagc tgctcgtcct ggacgcccgg gacctgacgc
     3481 gggtggccgc ggtggagatg ccgcgacgcg tccccgccgg agtccacggc agctggatac
     3541 cggagcgggg cccggacgcg gccggtgagc gcccttcgca ggactgagca gcggtggcgg
     3601 cggcccgaac cggccgccgc cacccccgtt cccgtacgcc ccgccgtgcc gggcgggatc
     3661 caacggccgg ggcggccgac agcgccggcc gccccggcgc gggacggtcg ttcagcgggt
     3721 gacgcgcttg ctcgccgtcg tcttcttcgc cccacgcttg gcggcggtct tcttcgccga
     3781 ggcgggaacg gcggtcttct tggcgggggt gcgcttcgcc gtggccgact gcggcgcggc
     3841 ggcgcgggcg gcctgcttct ccgtgtccgc tccggcgttc gcgagcgtgc ccgcgctgct
     3901 ctccagatgg gcgcggacga accactggaa ctgctccagc ccccgcaggt gctcgatgag
     3961 aaggtcctcg gtgacgggat cgatctcgct cacctccgcc agcgcctgcc ggtggtcctc
     4021 gatgacgccc gtgtacacga ggtccagcgc gccgaggtgc gcgatggcgt cggcgcggcc
     4081 cacgctgtag tcgtcccagg tccgctccgc gaccagcgcc cccggcgtgc cgtggggctc
     4141 cccgcccagc gccgagatcc gctcggccgc cgcgtcggcc atgtcccgga cagcggccgt
     4201 ctgcgggtcc agcatctcgt ggacggcgat gaagtgcggc ccgaccacgt tccagtggat
     4261 gtgcttgagg gtgagcgaca ggtcgttcag agcgtgcagc cgcagactca gcaggtcgat
     4321 cacccgccgg ccctcgtcgg tgtcgagccc ggggacggtg tagcgcgggg cgggggcgga
     4381 gggtgacatg tggctccttg acagatgggg tcgacggccg tgcgggctga ttcccagcct
     4441 tcttctgccc tgctgggacc ggctctcacg tttccccgcc gggtgttgcc cggcgggaca
     4501 tgcccacggt gccaacgttg caccgcaaca caggggcgac gcgccggatg agcccgaccc
     4561 gaacaccggg tctgatcagc gcgaacggaa gttccgccga gcgcaggtcc gttggcggcg
     4621 gaggtttttc gttgcccctt tccctgatgc cgtactgcaa cggccgcgtg acgccccatg
     4681 ctgtgtgtca cccacttggc gggccccgcc cggcgggcac ctttcccacg cccccggacg
     4741 cgggacggat gaacggagaa tcgcgtggat cggccagtgc cgcagtggag gaccttctcg
     4801 cagttccggc tcggggacgc cgcagacgtc ggggacgccg gggccgacga cgcggccggg
     4861 tacatcggag ggcaggtgcc gggccgtggg tgaactgcgc cccctggggc aggacctgac
     4921 gaacgaatca cgggcgctcg cggaagccct gcgggaactg ttcgcgggac tggacgtgtc
     4981 ggtgcgccgg tacgcggccc gacgccgacg cgacccgggc accttctccc gctacctgaa
     5041 cgggacccgc ttacccccct ggggggtgat catggacatg ctcgcggatc tggccgagca
     5101 ccgcggaacc accgtcaccg ccgagaccat cgagctcgtg cgcgaactct acgggtcggc
     5161 gttcgacgcc aactcctccc cgaaacacgc cgtccagatc atcgagcagc agttggccga
     5221 cgcggaccac gtatcgcgcc gctccagcgt ccgaggcgac gtcctcggcg acgccctgct
     5281 ggaccgcaag caccgcatcg cccacctgga ggtgcggctg aaccagatgg aggcggtgct
     5341 cgccgccgag cgggaacgcg ccgaccagct gacagccgcc catcccgacg tctccgagct
     5401 gctgggcgaa cgcgacctcc tgcgacagga ggtgacacgg ctcggaaacg aactccagga
     5461 ggcgcgggag cagcgcgcgg acgccgaggc gcgctgcgat ctcctggagc gccagctgga
     5521 agtcgtcgaa cgccccgcgg ccctgaacct gccgcagcct cagccgctga ccacgccgaa
     5581 agtcctcgtc gtggacgacc agcccgacaa cctgctcgcc atgacggcgg tcctgggcac
     5641 gctcgaccag gagctggtca cggtctcctc cggccgggac gccctcaagg cgctgctcca
     5701 ccacgacgac ttcgccgtga tcatcatgga cgtccagatg cccgagatgg acggctacga
     5761 gaccgccgcg cacatcaagc gccgcccgcg caaccgggac gtgccgatca tcttcctcac
     5821 cgcgatgggc gtcgaccccg agcacacggc ccgcggctac gcggccggcg cggtggacta
     5881 catcagcaag cccttcgacc cctgggccct gcgcgccaag gtcgccgtct tcaccgagat
     5941 ccacctcgaa cgacggatcg ccaactccgg tccctgacgc gcgcggcccg cgtgcggggg
     6001 cgctactcgg ccgcgtccgg cggcaggaag ccgtgctcgg acaggtcgaa ccagttgccc
     6061 tccgggtcgg tcgcccggta ctcggcgaac ggccggtcac cgccgcgcag caccgggcgg
     6121 gcgacaccgc ggtccgtgat ccggtcggcg acggaggcga cgtcggacac ctcgaagccg
     6181 aagtggttga acccggccgg cacgtccccg tccagacgct gctggatcag cgcgaggttg
     6241 atgtatccgt cggtgacgaa acggctgccg tccgggtcct ggtggaactc ctccatctgg
     6301 agggtgtccc ggtagaaggc ggcggcagcg gcggcgtcct ggaccaccag ggccaggtgc
     6361 ttgaggcggg gccggttcac gtctgttctc ctcgggtttc cggaacggtc atgttgtgaa
     6421 aggcggtgat gcgcgcgccg gtcccgtcgt ccgccacgac cgcctgcgcg tgcgtggtga
     6481 ggccaccggg ctcgatcacg gtcaccacgt ggaccagtcg gagtcctccg gccagcggac
     6541 ggaccaagcg gatctcgggg accaaacggg tgtcccggaa gggcccggcg aacaggcggg
     6601 cgtgcccggc caccacggct tcgcggcccc gcagctcctc accgcgcacg gtcacgaagt
     6661 cgacgtcctc ggcgaagacc gcgccgaacg cctcggcgtc gccgcgccgc cagccctccg
     6721 ccatcgcccg ccagagggcg agcacgccgt cgctgtcagt catcgcggcc cccgtcaccc
     6781 ggcaggacgc cgcccgtggc cggccggtgc acccgcagcg cgagccgccg gcactccgcg
     6841 tcccaggcgg acagggcgta accgtgcgcc ccgtgccgcc gctccacgta gcagacgacg
     6901 ttgaccggcc agccgctgct gcggaagaca tagcggtcca tctcggtggg gcactcgtcc
     6961 aacggatggg cgcgggcctg ccgggggccg agccggtgcc agtcggggtg catgtggacc
     7021 gagcccagga tgtccaggtt ccggcggtcc gcctcgcgcg cgatgcgcag caggtccgcc
     7081 gggtccagcc accacgcccg gaccgggttc tcgtaggccg ctccgaagcg cgggacgatg
     7141 gtcgcggcga actcctggcg ggcgttcggg tcggtggtgc gggcgttgcg tccgaaagcc
     7201 acgtcgtgaa ccagccagtc accgtccgca gccgttccca acagcaccgc gaaacacggc
     7261 accggatcat tctcggtgat gttcgcgtat tcccggaccg ctgccgcgag aaaacgatcc
     7321 aatgcggatt cggaaaacaa cacggaggaa gcatccggcg cgcggacggc atcctcgctc
     7381 tcgttcctgg tatgcgtcag cacataaccc acctgttcgg attccggcac tccgaaggcc
     7441 ggcatccgac cgtgtcaccg gctgcgccgg acggcaaccg accggcggcc gaggagtgcc
     7501 cggcgaaccg aaattgtcga cctctgtccg gaatgcgggc ctattgcatt cggcgataac
     7561 acttctgtcc ccccggccgc gcccgccgta ctatcgcgcc atgcgtctgg acgtacggca
     7621 cctggatctg gtcctcacca tcgccgaggc gggcagcctg cggcgcgccg ccgcccggct
     7681 gcacctcacc cagcccgcgg tcaccactca actgaagcgg atcgagcagc acttgggcgg
     7741 tgagctcttc gtccgtctgc cggacggagt gctgcccacc cgcgcgggct ccctcttcgt
     7801 ccgcgacgcc acccgcatcc ggcgggacct cgacggcctg acccgcaccg cccgccgcgc
     7861 tctccagggg gacgcggagg cgccggtccg cgtcggcggc gtgccggctc agcatttcag
     7921 cctgctgatc aaggcgctcg gcaccgtgct gcccgaacgc ggcgcgacca gccgcacggt
     7981 ccggtccacg gccaccgcca ccgccctgct cgcctccggt gaactcgacg tggcggtgct
     8041 gcgacggttc cccgactcgc ctctggcgct gccgcccgga gtcgcgcacc ggaccctgct
     8101 caccgagccg atcttcgtcg gggtctccct ggaccaccgt ctgtccggcg ccgggcggat
     8161 cgctctcggc gagttggcgg acgaggactg ggtgatgccg ccacccgacg acagcggcat
     8221 gaacggccac atggccgaca cctgccggcg taccgggttc gagcagcgcg tcgcgcacgt
     8281 caccgacgag tcgcacgtcg ccttcgccct gaccgccgcc ggcgacgcgg tgtgcccgct
     8341 ctacccgctg ggcagcgcgc gcgaatcgct ggccaccctc acgctcaccg gcgacccgct
     8401 cttccgcgac ctggtgctgg cctggcgcac cgattccccg gccgccccgg ccgtggacgc
     8461 actgtgcgca cacatcgcgc agggatatct cgcccttgtc gagaccgacg acgtgtatgc
     8521 acaatggtgg cgacgaggtg gagcggaatt cgctcttccc tagaggattc agaggagttc
     8581 cggtgccggt ccggggaatt aatcatgcgg ttctgtgggt acgcgacgcg gacgccagtg
     8641 cgcgtttcta cacggaagtc ctcggattcg gtgtggtcgg tgagtccggg gaggcgccgc
     8701 gtaaagcgat tttccttcgg gcgccggaat cggacaacga ccacgacctc ggcctgttcg
     8761 gcatcggtgc ggaggccgcc gagacccgtg cgggacgggg tgagaccggg ctctaccaca
     8821 tcgcctggga agtcccgacc ctgcacgatc tgcgcgccgt cgccgagcgg ctcgccgagc
     8881 gcggggcact ggtcggcgcg accgaccacg gcaccaccaa gggggtgtac gccaaggacg
     8941 tggacggcct ggaattcgag gtgtgctggc tggtaccgca cgagctgatc gacgacgagg
     9001 cccgcgcccg ccgcggcccg ctggacatcg acgccgagat cgcccggttc ggcgcgacca
     9061 ccgagggggc ctgtgcccgc tcggcccgcg gggcgtcccc tgctccgagc gccggctgag
     9121 gccgcccggc cggaaccgga agaacccgcc ccgcggcagt gcgcgggccg tgcgccacgg
     9181 gggatgatgg agatcgtgag gtcgccccgc cgaaccggct ccggagacgg gcccggcgcg
     9241 gcaccctccg ccgctgtctc cgaggggagc cgttcatgag cagggcgaaa gagttgttca
     9301 tcatcgccgt ggatccggga ccggagcagg ccgtggggca gggtgacctg tcgctcgctc
     9361 tcgccggggc cgagctgatc gacctcgtcg aggcggaggt cgtcacggtg gacggcgacc
     9421 ggatcgtgcc gggcgggcgg gccacgccgg gcgatcggct cctcggcgag gctgcggaag
     9481 ggctcatccg gcagccgccc tacgagcgga tcgaggactg gctgtggcgc cggggccgag
     9541 acctctcggc cgcctaccgg gccgccctgg aggaggacgg tgagctgacg cgaaagcgaa
     9601 gcggccgtcg gcccttcggc tcggaacgcg tggaaccggt cgatacgccc acccgccgca
     9661 gggcggccga gcgctgggag gcgaaggagc ccgtcctggc cgacctcgcc tcggcggtgg
     9721 gcgtcgacgc cggacggtcc gacgacgagc ccggcttcga cgacgacgcc gtgacgaccg
     9781 tcctggccgc cgttcacgac gcggtgatgg agttggaggc cgtacgccag cggcggacca
     9841 tcgagaacgc ggccttcgcc aacctctggc gcggaccgtg agacgggccc gccgtcgatg
     9901 cggacgggag gccgtcgagc ggacggcagg tcgttgagac ggacggcagg cgggctcgac
     9961 gggcgggctc tgcggacggg ctctgcgggc gcggagcccg tcagtctccc cgcccggccc
    10021 ggccgtcggt ccacaggcgc gggccgccgt ggtcgcgcag gcggcggaag aaggagagga
    10081 cgcccgcgcc gcccgtcgcc caccccggcc ccgacgccga cagcgtgttg tccgggatca
    10141 acggccgtcg ccgggtgccg ccgctgcggg cgaggatcag ccccgccacg tcctcggctc
    10201 cccgcagcag aagaccgtca ccggtggccg ccgccgcgtc gacgaggagt tctcccacgc
    10261 ccgccagccc gcagcactgc gagacggggc tcatcctcgg cgcgagatcg cggcacgtcc
    10321 gcgcacagcg caccccgagg tccgtcatcc gcccgtcccc ctcgtgcccg cccgcctcga
    10381 tcagcacggt cccgacgccc gccagccccc ggcaccagga gccgtaacgc cgatgggcct
    10441 ccgggcgcga cgccagctcc agcaacctcg gcgtgtgcga gacgagtacg gccagccccc
    10501 gccgggcggc gttaccggcg gacgggccac cggtgaagcg gtggtaggcg tgcaggaagt
    10561 gcacgacgcc cgcgaggccg tgcgcgaagc cgaacgtgaa ggccgcctcc gaggcggcgg
    10621 ccgactgctg cggctccgcg cgctcccgcc cgctctccgc cgcgagcagc gaaccgacgc
    10681 actcgcgcgc cgcggccagt cgcgcgtccc cctcctcgac ccgcccggcc gcgtacgcgc
    10741 gccgggccag cgccaacagc cccgtcccgg cccccgccgc cccgcctatc tggtcgccgg
    10801 tgtcgtcgta cgggcgcagg tgcgccgccg ggacggacgc cgcgggtgtc ccggtgagcg
    10861 cggcggcgga gtcgaggaag agatcgacgc cggtacgccc gacgtgcagt gcggcggaca
    10921 gtcgcggcag ggcggggtgg ccggcggtcc gccgggcgag ggcggccacg gcctcggaca
    10981 cacccggccg gtccgtgtgg tgcagcagct ccagacccac gccggccgca ccgtcgtaca
    11041 gcgtcagccc gaagccgggc cgatcgtgcg gggaccgcgg acgtacgggc aggtcggcgg
    11101 cccgggccgc gcagctcgcg gcggtgtgcc cgatcagctc gtccagcagg gcgcggccga
    11161 ccctgggcgg ggacgggagc ctgcgcccgg cggcagcggg cagcctcgcg cgatcgcgcc
    11221 accgccgggc gcaggcggcg cgccgttcgg gtcggaggtc caggagcccg gcgaccagtt
    11281 cccgcgtcgg ccggtgcgcg gagcccggca gcaccgcggt caggcaggcg agggtgcggt
    11341 cgcggttgac ggccgcgacc gcgtcgacga ccaccggctc cataccggtg agcgcgaagt
    11401 gcagggtcgc gcccaacgcg tacaggtcgt cggagggatc gggacggcgg ccggcacggt
    11461 acaccggaag cgaatagccc ggcgtcgcgc ccaccggccg gtcgccgtgc agggcgctga
    11521 caccgaagtc caccaggtgc gcgactccgt ccgcgtcgag cacgatgttc gacggcttga
    11581 ggtcgcccac cacgacgccg cgggcgtgca caccatcgag cagggtgatc agacggtccg
    11641 ccagagcggt gaccccgcgg cggctcgcgg tcccgccgcc cggggccgga cccgcgggcg
    11701 ggccgggggc gtcggcctcg tacggtcctc ggcccagtac gtcccggcac aggtcgccgg
    11761 gtccgcagtc ggtgatgacc aggaactcgt cgtccccgtg ccggaggtgg tcgcggagcc
    11821 gggggacgcc gtccagaccg gagagggcgt ccaggacggc gtgctcgtgg cgcaggcgac
    11881 cgcgcgcgtc gagaccgtcg gcgtcctccc cggtgtaggc cctggcctgt ttgacgatca
    11941 cctgctcgcc ggtcacaccg tccacggcgc ggtagacgtc accgtgcgga gaacgggcga
    12001 tgcccgaggt gatccggtag cgcccgccga tcagtcgggc cgggcggtcg ccgggcggcg
    12061 cgggcgggcg gaacgggtcg gcggcccacg gcggcgggcg gaaccgcgta cccgcccgcc
    12121 cggggaagcg cgctccgccg gggccggtca tgacgagtgc ggcgtcgtcg gagcccgccg
    12181 cccggaacgg gccgtagcgg tacgagacgg gggagtcggg ccggatccgc cggtcgctga
    12241 ggacccgggg accgggccgg ccggccagca ggcgcgcgag ttcgccgccg agcgccgtca
    12301 cgtcgtccgg gcgcggatag acggtgaccg ccttcccgac gagcgcggga tcgcgcacgc
    12361 cgctgttcat cgcccgcaac acctccgccc cacgggcgaa cttggcgctg cacgcgtagc
    12421 gcagcagcac cggaacgacc aggtccacga cctgtgacag gtcgtcggcc cgcgccgaca
    12481 catgcaactt ccagccgtgc tgagggagtt cgttcgtgag tccggcggcg aacaggcaga
    12541 gccacggacc gtcggcgacg acgcgccgct cgcggcccgc gagcagcgac gtcaggcggt
    12601 cctccagggc gcgaccgccg tcgggcccct cgcatccggc gtccgggctc ccgggcccca
    12661 gggaggggga cgggcccgcg cggtacgccg ctgaaacgcg cgcctcggga ccgtccgcgt
    12721 cggccggggc cgtaccggcc gacacggcgc ggcctcctct agtcgcagcc gaagcgggtc
    12781 gtcgccgtcg ggaaggggtc gggcagacac gcctcgacac ggcggctcgg gtccgcctgg
    12841 tcctcgaagg cgatgtcttc ttcctccacg gccacgtcga gtggtccggc gtcgcggatc
    12901 tgcagtacca aggggctcat ggcggtcctt ttctgtgcgg agaaggaggt gaacggtcca
    12961 tggtgccggg cggtcgtgcg tgctccggtc agtctcgcga acgagggccg cgcgggcaag
    13021 aggcgcgaac ggccccgtcg gacggcctcc gtcgccccgc ccgctgggca agtcggcttg
    13081 ttctcccgca cggctgcctc accacccact gttcgccgtc gggcagtcct gattggcttc
    13141 ggacgccggg cggcgaccgt cgggctcgga ccaccggcgc ctcctgcatc gccccgcccc
    13201 cgaccccggg attccatcga cttgaggaag aggtccttca tgcacgtcac acgccgtctc
    13261 accgcgatgg ccgccgctgc cgccgcgatc acgctcgctc tcgtaacccc cgccgcagcc
    13321 gccccggctc ccgctcccgc cgccccggct cccgctcccg ccgccccggc tcccgctccc
    13381 gccgccccgg cggcgaccgc gtccgcggtg ggcccggtgc agctccccat cggcgggctg
    13441 ggcagcggcc cgtacaacgt cgccgtgcag tcggccgtcg gcaccgcgag ggacaacgcc
    13501 gtggccagag gcttcgatcc cgcccggtgc accctggtca agggcccgac gatcgtcaac
    13561 caactcccca acggatacgt gcaggtcgcc gtcgaatacc tctgcgcggg cgatccctac
    13621 gcgtcgggtc cgacgttcgt cctgaaccgg tatcacaaga gctccgacac gcagagcaac
    13681 agctggtacg cgcccgccgg ataccagttg caggggccgc tgggctcgct ctacacgtac
    13741 gcggcgcccg acaccacccc gctgtacctc tgccaggtca ggggcgacca cttcaccagc
    13801 acggacgtca actgcgaggg ccagcagtac gtgacccgac tcggctggct gtacaccagc
    13861 ccgccggcag gcgtgggcac ggtccagctg ctccgctgcc tgcgcaacga gaaccggcag
    13921 atcttcgact ccatccagcc caactgcgaa gggcagatcc acggaggcgt cctcggatac
    13981 accctggcct gacccctgtg gcgaccacct ctgccggcag aggtggccgc ccggcgcggc
    14041 agcccgccgt cgggcgcctc tgcgcaggtg gccggacgtg agcaagtgcg cagccattgc
    14101 tcagatatga cgcgcgatca gtggggagca gcggtcggcc atcgacgcgg aggtgagcgt
    14161 cggtcctgcc tgcacaccgt cgctgacctg cggaaacgga gttccgtccg tccgctccga
    14221 ccgtgtttca gccgatcgac acgaaacacc acgagaacct tcacgactgt cacgtccggt
    14281 cgaacgcgcg tagatttcca ggcgatccca gacagatctc tcccttcttt gaccagcctg
    14341 cggacgacga cgatgtcgcc gctccggcgg ccggtgtccc atcggccgac atgtcccacg
    14401 tcgaaaacgg attgtcagcc acatgccccg tcacgcctta tccctcagcc ccgcgtccgc
    14461 tttccgcgcc gccgccggcg ccccgctgcc gccgggcgcg accacgagtc cgacccgggg
    14521 ttcgtcgagg tcgggcgtcc gcgtccttcc cgaacgggaa ccgggcaggg gcggtgccac
    14581 gtgatcgtct cgctggtggg ctcggacggg gccggcaagt cgacggtctc ccggatcgcc
    14641 gccgagcgga tgtccgccgc cggcgcgggg atcgagcggg tggaccgatg ggacatcatc
    14701 ggcagccccg cctaccccgc cacccggttc ctgggatccg atgtacgcga cacccggctg
    14761 tgtgtcgcgg agatgccgaa cacgtcccgc ttcctcttcc tgatgtggtc catgtcccac
    14821 gcgcttctgg gacgcggccc ggagtccgtg cggcccgacc ggatcaccct gctcgacgga
    14881 tactggatga agcacgccgc cggagagatc gtctacggtc tggacagcgc ctgggtcgaa
    14941 agcgtcgtcg ccggcctccc cgtcagtgaa caggtggtct acctgcggct ggatcccaag
    15001 gacgcgtggg agcggaaggt cgggcgcgac gtcgtcccgt acgagtgcgg gatggacccg
    15061 gactgctcgc aggacagttt cctgacccac cagggccgca tactcgacgt gctcgacggc
    15121 tgggccggtc agcgcggatg gcagatcgtc gacgccgccg cgcccctcga cgacgtggtc
    15181 gaccaggtgg tctccaccgt caccgccgcc tccgcggttt ccacccgttc cgctgtcgcc
    15241 gccgcctccg cgcaggccgc accgccgcag cggtgagcgg ccctggagcg gcctccggcc
    15301 cgcccggacc gccggtcccg ccgcccgacc ttcaccgagg ccggtggcgg gcccgccccg
    15361 gaccgcgccc gcctgccgcc gacccggtcg ctcccgcggc gctccgcgcc cgcgcggact
    15421 ccggcgaccg gtgagcccgc acgcgggccg cccgtgcgcg ggagcgcacc gggccgtctg
    15481 acgacgacgc cccagtccat caggtccgta cggcgggccg gtggcccccg cccgcgtcgc
    15541 ctcgcacacc gcgctcgccg aggcacgccc gcgcagcctt cacccctctc accaaggaga
    15601 cccaccccat gagttcgacg cgtctcgcca tcgtcggcgg cggccccagc tgcacctacg
    15661 tgatggaccg cctcgccgcg gcggcgacgg cggcggccgg gccgctctcg ctcgacgtcc
    15721 atgtcttcga ccgggcaggg ctgttcgggg cggggcaggt ccacagcccc gaacagcccg
    15781 tcaccagcgt cctcaaccgc atcgccggac aggttgcgtt cgcggccgac gagagcgtcg
    15841 tcgacgccgg gccgctgctg ccgcgcgagg accggccgac cctgcacgcc tggtgccgcg
    15901 cccggtacga ggagaccggc gaccccgtct tcgacctcgc ggccgaggac tcgccgaagc
    15961 gctacgtcca cggcctggcg ctcgccgacc ggttccgcag atacgccgcc atcctgggag
    16021 acgtggcggg tgtgcgggtc cacctgcatg agcgggaggt gacggacctg gaggaactgc
    16081 cggacggcag actcggagtc gtcgccggcg gtgaacgcgt cctggaagcc gacgacgtgc
    16141 tgctgctgac cgggcactcc tccaacgacc cggcccgcta cccgcggcag gcggaatggc
    16201 aacgcttcgc ccgaagccac cgaaccgggt tcgtcccctc cgtctatccg ctcgacaagg
    16261 cgttcgcacc cggcgaggcc ggccccggaa ccacggtcgg ctgcgccggc atgggactca
    16321 ccggcatcga cgtcatcctg cacctgaccg aaggcagggg cggggtgttc gtggagcagc
    16381 cggacggaac cctggcgtac cgggcctccg gccgggagcc cgattccgtc gtcatgttca
    16441 gcggctccgg actgttcacc ttcacccgcc cgttcaacgc caaggagcgc gacaccggaa
    16501 agctggagca ccgaggcgtc ttcctcaccg aggacgcggt gctccggctg cgccggtccg
    16561 tgggccggcc cgtcacgatc ggcgaccgtc cgcagcggca actcgacttc cgcgcgcacg
    16621 tcttccccct ggtggtgctg gagatggccc acgtgtacca caccaccctg ctgggcggcg
    16681 cgttcggcga ccgaacggcg gcggcggtcc ggcccgtgta cgaggcgttc ctcgcggacg
    16741 gcggcggtgg ggcctcctcc gaagcgtccg tccggcgtct cctcgccccg ctggaggccg
    16801 aggtggaccg cgcggcggag accatcgacg cgatcctgtc cggcgggctc gcactcgccg
    16861 aggcgcggga acgcgacggg gacgtggagg cggcgctgcg ccgcttcctg gaggtggtgt
    16921 tcgggcccga gcgggccggg gccgtcgccg cgctgagcgg tgatcctgcg gagttcgcgg
    16981 acgccgtcgc agccgccgat tcgccctggc gccacccgaa gagcgtcgcc ggccagcgct
    17041 tctcctggga gcgccagatc cgtccgatcg accgcgacgc ctccgccacc cccgcgcggt
    17101 accgggcggc gatgctggac ttcctcgacc tcgaccaccg ctgggccgtc cagggcaacc
    17161 tggccaaccc ggcgaaggcg gcggccgacg gcgtctggcg ggacctgcgg aacgtgctgg
    17221 cggcagcggt cgacttcggg ggagtgaacg cggcgtccca ccgcgacttc ctcgacgtgt
    17281 tcatgcgcca cctcaaccgc ttcgtcaacg ggtccgcgct ccggcccatg gagaagatcc
    17341 gcgcgctggt ccggcacggc atcgtcgacg tgtcggccgg tccgggggcg gaagtggcga
    17401 ccgacgagga gagcggacgt ttcgtggtgc gcgggatcac cggagcggtg ctgcccctcg
    17461 acatcctggt cgacgggcgc gtccatccct tcgacgcggc gaacgacgtc cttccgctct
    17521 accccaacct gctcgggcgc gggctcgtcc gcacctggcg caaccccggc gtcggcgaac
    17581 cggacttcgc gccgggcggc ctcgacctca ccgaggagtt ccacccggtg cgggccgacg
    17641 gcgaggtgga ccggcggatc acggtgctcg gctggccgag cgagggcgtc atgttcttcc
    17701 agtacggcgc gctgcgcccg gaccagaacc accacctgat gcgggacatc ctgtgctgga
    17761 tgcgggagtt ctggggtgat cggggccccg cgtccgaatc cggcggttcc ctcgccgccg
    17821 tccgggcgtg accacgtacg acatcaagga gaacccgcat ggaagacacc acctggcccc
    17881 gcgtggagcg actgcggcac tggctggacg ccaacgccgg tccggaggcg acgggggacg
    17941 tacggctgtg gcgcgtcctg aagatcagcg aggaggtcgg cgaggtcgcc gaggcgatgc
    18001 acggcgcgac gggagccaat ccgcgcaagg gcgcgtccca cacctgggac gacgtccaca
    18061 cggagctgtg cgacgtgatc gtgtcgagca tgatcgcgct gaccacgtgc acgccggacg
    18121 ccgcgaggct gctcgacgaa cgactccagc acctggtcga ccgcgtgatg ccgccccggg
    18181 ccgcccggtg accgaacgct gacggctcgc gcgggccggt cggtgcgtcc gccgcacgcc
    18241 cgaccggccc cgcgacctcc tcccggccgc cccgggcggg ccgtcgcccc tgcccggacg
    18301 gcaactgatc gatcgcatga tgaagttttt cattccgcag ggttgtcttc atcttggtga
    18361 acctcttcac tgtgacgtac cccggacgtc aacctctgag gcggaacgca ccatgagcga
    18421 cgcgagtgac gcggtctccg gcaaggacat gaacatcgag gcgatggtcg ccacggtggg
    18481 cctgcagatc aaagtcctgc gcaagctggc cggactcaca ctcgacgaac tcagccgccg
    18541 ctcctccgtc tccaccgggc tcatcagcca ggtggagcgc ggcaagggga acccgtcctt
    18601 cgcgaccctg gtgcagatcg cccacggcct cgaagtaccg gtcggccgcc tgttccacct
    18661 ggccgagcag atcagccccg tcgtacggcg cgacgagcgc cgcaccctgg acttccacaa
    18721 caccggcagc ggtgaacccg acgacgcccg ctacgagttg ctgaccccca gcctcaacag
    18781 cgccctcgaa gtcatctggg tggagaccca gccggggcac gacacgagca gcaccccgtt
    18841 ccgccacagc ggcgaggagt tcggcatcgt gctctccggc gtgaaggacg tctatctcga
    18901 cggagtacgc caccggctgc acgccggaga ctccatcacg tactcctgca gcatcccgca
    18961 ctggtacgcc aacagcggcg acgagcccgt gacctcgatc tgggtgatca ctccgcccac
    19021 ctggtagtcc cgcggccctc gacgccccgc ggcgtcgcga ccccttttgg ccgcgacgcc
    19081 gatcccgcac ggccgaaacc tggccgacgc aattcccacc tgcgaggtgc ccatggcatc
    19141 gctcaccgat cgttcccccg cctctcccgg cgccccctcc ccgcggcgca ccctcttcgc
    19201 actcggcgga ggcaacgccg tcgagtggta cgactggatg gtctacggcc tgctggcctc
    19261 ctatctgggg ccgcagttct tcccgtccac caatccgctc tccgccaccc tgtccgcact
    19321 cgccgtcttc gccgtcggat tcgccgcgag acccgtcggc gcgctcgtct tcggaaccct
    19381 ggccgaccgc gtcggccgac gccgcatcat gctgctgtcc atcggcggca tggtcgtcag
    19441 caccgccgtc atcgccgtac tgcccaccca cgacagcatc ggtgtgtggg ccggggtgat
    19501 cctggtcgcc tgccggatcg tgcaggggat ctccaccggc atcgaggccc cgctgaactc
    19561 cgcgtacgtc gtagagatgg cccccgaggg ccggaccgcg cgctacggcg gcatcatcag
    19621 cgtgtacgtc cagtccggca tcatcgccgc ctcgctcgtc gccttcgtga cgagcacggt
    19681 gctgggcgcc acggcgatgg aggaatgggg ctggcgcatc cccttcgccg tcggggccgt
    19741 cggcggcgcg gtcttcctgc ggctgcgccg gagcctcccc gagaccctgc acacctccgg
    19801 cgaggccccg gccgcctcgc gcgtctgggc cgacgtcggc cgcaacaaac tcgccctgct
    19861 ggccatcgtc ttcgtcgtgg ccggcgcgca ggcgctcaac tacacctggt cgaccggact
    19921 gcccaacctg gcccgtaccg tccacggcga gaaccccagc gcggtcttcg ccgtcagcac
    19981 cctcagcgga ctctgcgtcg cggcgctcta cccgctcgtc ggacggctcg cggaccgcaa
    20041 acggatctcc cgcaccttcc tcgtcgcccg gctcgcggcc gtaccgctgg tgttcgccgt
    20101 cctcctctac caggccccgg gcatggtcct cttcacggtc gtgatgatga tcggggcgcc
    20161 cgtcctcgcc ttcaccatgg ggctctacac cacggtgtcc gccacgctga tgccgatgag
    20221 ctgccgggtc accggggtgg gcatcggcta cgccgtcggc gtcgcgggat tcggcggcac
    20281 tgccccgtac atcctgctgt ggctccagga catcgggctg ttctgggtgt tcccggtgta
    20341 cgtggccgtc ctctgtctgc tgagcgcgct gttctacacg ctcgccttcc gccgcggttc
    20401 cgtccgcgtc ggaggctgaa aggagtacct gtgtctccga accccgagaa gttctcggca
    20461 gaaacgattc ctctcgacgc ggtggaagca cccgtcgtcc aacgttccga cgtgatcgtg
    20521 gtgggcggcg gccccgcggg ggtcagcgcc gccgtctccg ccgcccgcag cggcgccacc
    20581 gtgaccctgc tcgaacggta cgcggccctg ggcggcctcg cctccggcgg aatggtcctc
    20641 gtcctggacg acatggtcaa cggcgacgag atcaccgtca ccggagtcgt cgacgaatac
    20701 gtcgagcgcc tgaccgcgtt ggggctcgcc gtccacccgc cggccgagga gcgcgtctcg
    20761 tcgccgcaga tgtgggccaa gtggggccgc tggggcgcct acgacttcca ctcgcggctc
    20821 agccccaaac cgatctgcta cgcggtcgcg ttcgaccccg acggctggaa gcgcgtctcc
    20881 aacgacctgg tccgcgagag cggggtcaac ctgcggctgc acagctggtt ctcccgcccg
    20941 atcgtccagg acggcgagat caggggcgtg gtctgcgaga ccaagtccgg cccgcaggcg
    21001 gtcatgggca gcgtcgtcgt cgacaccacc ggtgacatcg acgtggcatc ccgcgcgggc
    21061 gccgcgcaca cccaggacag ctacctcacc acgctcgtct tccgcctcgg cggagtcgac
    21121 acggacgagg cggaacggtt cgagcaggcg cacccgcgcg aagtccgcgc catcaacagg
    21181 aagatcaagc gcatgctcgg cggcgcctgg gagctgtggt ggctcaagac gcccatcccc
    21241 ggtgtcgtgt ggtgcaactg cccccacctg accggattcg acggcaccga tcccgcctcg
    21301 ctcaccgagg ccgagttcga ggcgcgggcc cgcatcgccg ccgtgctcga cacgatcagg
    21361 caggacctgc ccggcttctc cggcacgtat ctgctcgacg tcgccgagca gatgggggtg
    21421 cgccagacac gactcctcca gggcgagtac gtcatgacca aggacgacat caccagccgc
    21481 cggcacttca ccgactcggt cgcccggggg agggactact actacccgta ccgctcgctg
    21541 ctgcccaggg gcgtggaaca actggtcgtc gccggccgcc actactcggc cacgcccgaa
    21601 gcccagcgca tgtcccggga gatcccgccg tgcatggcga tgggccaggc cgcgggcatc
    21661 gccgccgcgg cggccgtcga gcagggcgtc cgcgtccgcg acgtcgaccc cgccgtcatc
    21721 cagcgccgga tgcgcgacca gggggccgac ccgggcgacg taccggcggc caacgcgacc
    21781 accgaccagt cccaggaggt cccggcatga ccgtcacgca acagctcacc ggcatcaccg
    21841 tcatcgactt cacccaggtc tacatgggcc cctcgtgcac ccagctgctc ggggactacg
    21901 gagccgacgt gatcaagatc gaacgcccgg gagccggtga cacgacccgg acgaccatcc
    21961 ccgacccggc gggcctggac aacccgatct tcctctccgt caaccgcaac aagcgcagtg
    22021 tcgccctgga cctgcgcacc cccgagggcc gcgcggtggt cgaggacctc gtacgcggag
    22081 ccgacgtcgt ggtgagcaac ttccgcgccg gggtgatgga acgcctcggc ctcggctacg
    22141 acgccgtacg acgcctcaac ccgcgtgccg tctgggcctc cggcaccgga ttcggccccg
    22201 agggaccgta cgcccacaag ggcggacagg acgccgtggc ccaggcgtac agcggcgtca
    22261 tgtggcggcg gaactcggaa gaggacccgc tcaccctcta ccccaccacc atctgcgact
    22321 acatcaccgg ccagcacctc ctccagggca tcctgctcgc cctgctgcaa cgcgaacgca
    22381 cgggcgaggg ccagcgcgtc gacgtcagca tgtacgactc catgctgcac ctgcagatgc
    22441 aggaggcgtg ccagcagctc atgcgcggca ccgagatcaa ctgggccgcg atgccgctca
    22501 ccggcgtgtt cgccaccacc gacggggcgg tgtgcgtcgt cggcggcttc acccgcaacc
    22561 ccctgcgcgc actgagcctc gccctcgggc tggacgagga cctgtccgca cgcggcgatc
    22621 tcgccaccct ggcccagcag ttcgccgcca ggccgcggct ccagcagatc ttcgccgagc
    22681 gcctggccac ggaatccacc gcgcactgga tcgaacgcct cgaacaacag gacatcctgt
    22741 gcgcc
//
