LOCUS       NZ_ML123034            26577 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6140236
            Orig. end                         :: 6166813
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..26577
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26577
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26577
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16577](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16577
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(152..1093)
                     /locus_tag="EES43_RS26860"
                     /old_locus_tag="EES43_26505"
     CDS             complement(152..1093)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="EES43_RS26860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26505"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_124271143.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHGGAPPTGTAAAAYQGRLRIALGITLSVMVMEIVG
                     GVLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCLL
                     LLGVGGFLVFEAVERFITPADTKGGLTIAFAAVGLVANVVSLSLLTRGQQDSLNVRGAY
                     LEVLADTLGSVTVLVSAGIIMATGWQAADPVASLLIGLMIVPRTVKLLRETLNVLLEAA
                     PKGVDMEEVRAHITELPGVIDVHDLHAWTITSGMPVLSAHVVVRQEMLDSIGHEKLLHD
                     LQGCLGSHFDVEHCTFQLEPSGHAEHEAKLCH"
     misc_feature    1188..1202
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1251..2240)
                     /gene="galE"
                     /locus_tag="EES43_RS26865"
                     /old_locus_tag="EES43_26510"
     CDS             complement(1251..2240)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-205). E-value:
                     9.6e-10. Score: 29.9. Matches aSDomain:
                     nrpspksdomains_EES43_RS26865_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152793.1"
                     /locus_tag="EES43_RS26865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26510"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_124271144.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-16, bitscore:
                     58.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-11,
                     bitscore: 42.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMVAAGEEVVVLDDRSTGVAARLPESV
                     TLVEGSASDRALLDRVLTGHGVSGVIHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAV
                     VAAGVRDFLFSSSAAVYGVPDVDVITEETPCLPINPYGETKLAGEWLVRAAGKAHGLST
                     ACLRYFNVAGAAAPELSDTGVFNIVPMVFDRLTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     TDLAEAHLAVARGLRERAGGDLTVNVGRGEGVSVRELTAVIGEVTGHRADPVVEPRRPG
                     DAPRAVASAARLSKELDWTARRSVREMVESAWEGWCLHHPEARARQRS"
     aSDomain        complement(1626..2042)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS26865_NAD_binding_4.1"
                     /evalue="9.60E-10"
                     /label="EES43_RS26865_NAD_binding_4.1"
                     /locus_tag="EES43_RS26865"
                     /protein_end="205"
                     /protein_start="66"
                     /score="29.9"
                     /tool="antismash"
                     /translation="VSGVIHLAAKKQVGESVEKPLLYYRENVAGLAVLLEAVVAAGVRD
                     FLFSSSAAVYGVPDVDVITEETPCLPINPYGETKLAGEWLVRAAGKAHGLSTACLRYFN
                     VAGAAAPELSDTGVFNIVPMVFDRLTRGEAPRIFG"
     CDS_motif       complement(2151..2237)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EES43_RS26865_0001"
                     /evalue="8.10E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="EES43_RS26865"
                     /protein_end="30"
                     /protein_start="1"
                     /score="24.9"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMVAAGEEVVVL"
     misc_feature    complement(2304..2318)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            2559..4337
                     /locus_tag="EES43_RS26870"
                     /old_locus_tag="EES43_26515"
     CDS             2559..4337
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955402.1"
                     /locus_tag="EES43_RS26870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26515"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_241192543.1"
                     /transl_table=11
                     /translation="MQTAADPGDAAALLAAVPANSRVALVDPRFVGHVHALRLGLTDPR
                     FPAAAVPGALTAQPEARAALTRALRRTGAAVGAGAPAVEPDADPTPADRTAPAPADGTV
                     PGRVAAALEAEGVDVRRPELGSLTAAVPTDDDQRAAAAAGLASVDGEAVRLRGAVKAHD
                     GFFTTFCVSPYSRHIARWCARRGLTPNQVTTASLITALVAAGSAATGTRAGYVAAGILL
                     LVSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLALGAARGGDDVWVLAL
                     GAMVLQACRHVVDFSFNEANHDAVANTSPTAALSDRLDSVGWTVWLRRMIVLPIGERWA
                     MIAVLTALTTPRVVFYALLVGCALAACYTTAGRLLRSLTRRARRTDRAARALADLADSG
                     PLAQAVAAVAPGLRGAFTAPAVALLAALVMAGSALFLPYGSALTVVAAALYVLLSGLAV
                     ARPLKGPLDWLVPPFFRAAEYGTILVLAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIR
                     GGTGAPPRWLVRVLGGHEGRTALVVVLAAVLTHASGFTTALTVLAVAVALVALVESIRF
                     WVSSSAPAVHDEGELA"
     gene            4334..5071
                     /locus_tag="EES43_RS26875"
                     /old_locus_tag="EES43_26520"
     CDS             4334..5071
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="EES43_RS26875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26520"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_124271146.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.6e-12, bitscore:
                     44.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDRTVLDLTLANFAEV
                     GLTEVAIVVGYRKEAVYARKAELEATYGLSLTLIDNDKAEEWNNAYSLWCAREVLKRGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTEKSLADEEMKVITAEGKGVQRITKLM
                     DPSTATGEYIGVTLIEAEAAEELADALRTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     TVTWVEIDNHDDLAKGRVIACQY"
     gene            5059..6120
                     /locus_tag="EES43_RS26880"
                     /old_locus_tag="EES43_26525"
     CDS             5059..6120
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="EES43_RS26880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26525"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_124271147.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.3e-18, bitscore: 65.4,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.5e-09, bitscore:
                     35.1, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISSSGKLAIAISD
                     GSGRALRERLAPVLPGADWYSVSDGTIDSAVKLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGLPLVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAISNISCVADWELAHEVNGEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLYPQRAASHGEQVGLGACFAMHLRG
                     ARQESLLMASILRRHGLPVVPEEIGFSVDEFVRAVDYAPQTRPGRFTILEHLNLSTDQI
                     RDAYADYAKTISS"
     gene            6098..6877
                     /locus_tag="EES43_RS26885"
                     /old_locus_tag="EES43_26530"
     CDS             6098..6877
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="EES43_RS26885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26530"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_124271148.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPPGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     DTRVTPNQLTYVMTVAGVLAAPALLVPGIGGALLGVLMVQLYLLFDCVDGEIARWKKQY
                     SLSGVYLDRVAAYLCDAAVLVGLGLRAADLWGQGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGMPPVQESASEPRSSGMALARRAAGALKFHRLILGIEASFVILLAAVLDT
                     IGGDLFYTRLTTAVMAGIALLQTLLHLVSVLASSRLK"
     gene            6886..7758
                     /locus_tag="EES43_RS26890"
                     /old_locus_tag="EES43_26535"
     CDS             6886..7758
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="EES43_RS26890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26535"
                     /product="glycosyltransferase"
                     /protein_id="WP_206430211.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-10,
                     bitscore: 40.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVAAQDGDRIEVVVVGNGAPVPD
                     VPAGVRTVELPENLGIPGGRNVGIEAFGPSGADVDGLLFLDDDGLLPNRDTAELCRRAF
                     EADPRLGIITFRIADPDTGTTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVLAEVG
                     GLPDAFFYAHEETDLAWRALDAGWMIDYRADMVLHHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAALVPLYVGSWLLLTLLRRPSPPALRAWFGGFREGWSAPCGPRRPMKWRTVWRL
                     TRLGRPPVI"
     gene            7860..8789
                     /locus_tag="EES43_RS26895"
                     /old_locus_tag="EES43_26540"
     CDS             7860..8789
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="EES43_RS26895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26540"
                     /product="ABC transporter permease"
                     /protein_id="WP_124271150.1"
                     /transl_table=11
                     /translation="MSDTTHDGGVALGTLSSADEGLSAAQTAAKYGLTVSGARPGLLAY
                     MRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVVTPLLNALVYYLIFGLILGTREGIP
                     NDVFVPFLVTGVFVFTFTQSSVMAGVRSISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSMIVLVAVAVIFGSYPSLSWLLVIPALVLQFFFNTGLALIMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLRDKPAWIADVLQYNPAAIYMDLVRFAMIDGYGSENLPAHVW
                     AVGALWAVLLGVVGFVYFWKAEERYGRG"
     gene            8782..9567
                     /locus_tag="EES43_RS26900"
                     /old_locus_tag="EES43_26545"
     CDS             8782..9567
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="EES43_RS26900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26545"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124271151.1"
                     /transl_table=11
                     /translation="MAEDNTQGRIPTVIADDVHIVYRVNGTGGGRGSATAALSRIVRRG
                     KGESRGVRTVHAVRGVSFTAYRGEAIGLIGTNGSGKSTLLRAIAGLLPTESGHVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSRDEIRERYREIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRVRSEQRIRELRKEAGTVFLVSH
                     NNKSIRDTCDRALWLEKGELLMDGPTDEVLKAYERETGK"
     gene            10001..10909
                     /gene="hpnC"
                     /locus_tag="EES43_RS26905"
                     /old_locus_tag="EES43_26550"
     CDS             10001..10909
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552438.1"
                     /locus_tag="EES43_RS26905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26550"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_124271152.1"
                     /sec_met_domain="phytoene_synt (E-value: 1e-36, bitscore:
                     125.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 9.5e-40,
                     bitscore: 135.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSRQARTGDATLDKAADENFPVAPFFLPRAWRGDLMAVYGYAR
                     LVDDIGDGDLAPGGADARHLGLEPEQSEDRLAMLDAFETDLHRVFAATGEPHHPLLRAL
                     RPTVRRRALTPEPFLGLIEANRQDQKVRRYATYAELAAYCELSANPVGRLVLALTGTTS
                     PERVRRSDAVCTALQIVEHLQDVAEDLGRDRIYLPAEDMDRFRVTESDLAAPSAGASVR
                     ALTAYEAERAHELLNEGAPLVGSVNGRLKLLLAGFVAGGRSALTAISAAGFDVLPGPPK
                     PTKPSLLREVGVVLRRARGEG"
     gene            10939..11859
                     /gene="hpnD"
                     /locus_tag="EES43_RS26910"
                     /old_locus_tag="EES43_26555"
     CDS             10939..11859
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492033.1"
                     /locus_tag="EES43_RS26910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26555"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_206430130.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-58, bitscore:
                     195.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.2e-71,
                     bitscore: 239.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPPVQAAYSYCEAVTGQQARNFAYGIRLLPNEKRQAMSALYAFS
                     RRVDDIGDGELDPETKRTRLESTRRLLDRVRAGAVDEDDTDPVAVALTDAARRFPLPLG
                     GLDELIDGVLMDVRGATYETWEDLKVYCRCVAGAIGRLSLGVFGTEAGAPGAERAAEYA
                     DTLGLALQLTNILRDVREDAANGRTYLPADDLAKFGCSAGFHRATPPPGSDFAGLVHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARHVSRLTARGRG"
     gene            11987..13372
                     /gene="hpnE"
                     /locus_tag="EES43_RS26915"
                     /old_locus_tag="EES43_26560"
     CDS             11987..13372
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378207.1"
                     /locus_tag="EES43_RS26915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26560"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_124271154.1"
                     /transl_table=11
                     /translation="MSDETPRPGAVVVGGGLAGVTAALRLADAGLDVTLLEGRPRLGGL
                     AFSFQRGDLTVDNGQHVYLRCCTGYRWFLDRVDGAHLAPLQDRLDVPVLDVGRPAGPRL
                     GRLRRTGLPVPLHLAGGLAAYPHLSLAEKAGVGRAALALGRLDLADPELDRIDFATWLR
                     RHGQSRRAVEALWDLVGVATLNATAADASLALAAKVFKTGLLSEPGAADIGWASVPLGE
                     LHDTLARKALDTAGVRTELRAKAGSVTRTADGRWSVETAGERIPADTVVLAVPQTETHD
                     LLPDGALDEPDLLLDIDTAPILNVHVIYDRKVLRRPFFAAIGSPVQWVFDRTESSGLTG
                     PGQYLAVSQSAARDEIDLPVAELRTRYLPELERLLPAARGAGVRDFFVTRERTATFAPA
                     PGVGRLRPGPRTRMPGLQLAGAWTATGWPATMEGAVRSGLSAADAALKDLGRPHGHPLQ
                     EAA"
     gene            13369..14472
                     /locus_tag="EES43_RS26920"
                     /old_locus_tag="EES43_26565"
     CDS             13369..14472
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="EES43_RS26920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26565"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_124271155.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-59, bitscore:
                     200.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAFDTVADTTDVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDADGRPADGDGGKAVRPALALLSAEAAGAPAEAGVPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEILLELGTVE
                     AGRAARRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADVLESYGHHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGDASERLGELLAADAKSSDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHGVDMPHHVRAQLTALADFVVVRKR"
     misc_feature    14480..14496
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     gene            14577..16577
                     /gene="shc"
                     /locus_tag="EES43_RS26925"
                     /old_locus_tag="EES43_26570"
     CDS             14577..16577
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964848.1"
                     /locus_tag="EES43_RS26925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26570"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_124271156.1"
                     /sec_met_domain="T2TS (E-value: 4.5e-146, bitscore: 486.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANLHAAPAGHPTDTTTAADDVLAAARRAAERSVE
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPGTTEAAARFIRGEQLGDGTWN
                     TFYGGPADLSATIEAYVALRLAGDRPDAPHMARASGWIREQGGIAAARVFTRIWLALFG
                     WWKWDDLPELPPELMFLPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     TDPAHPNPPRKPAPAASWDGFFQRLDKGLHLYHKVAPRPLRRVAMNAAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGIASLDRFAVRREDGARMIEACQSPVWD
                     TCLATIALADGGLRPDHPALVRAADWMLAEEITRPGDWSVRKPELAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVCHPDPARLEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGLSAHPRTRAGIDWLLAEQAPCGAWFGRWGV
                     NYVYGTGSVVPALIAAGLPAGHPAIRRAVIWLETVQNDDGGWGEDLRSYREEKWIGHGE
                     STASQTAWALLALLAAGRRDTRAAARGVTWLTDAQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVHGDPFADRADAREGA"
     gene            16577..17215
                     /locus_tag="EES43_RS26930"
                     /old_locus_tag="EES43_26575"
     CDS             16577..17215
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520235.1"
                     /locus_tag="EES43_RS26930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26575"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_124271157.1"
                     /transl_table=11
                     /translation="MGDDPGPTTPLLVACALGIEQLALRSGRGAAGPVRVLRTGMGPRA
                     AEAAVGRLLGSGGVLGAAVVAAGFCAGLAPGMHPGDLIVAEETRDADGVTPCVGTGLLV
                     DALARAVPGRTVHTGRLTGSDHVVRGPERAALRADGAIAVDMESAATLRTALCHGPRPV
                     AAVRVVVDAPEHELVRIGTFRGGISAFRVLRAVLPAFYEWHRSLSLPRR"
     misc_feature    17195..17197
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17221..18240
                     /gene="hpnH"
                     /locus_tag="EES43_RS26935"
                     /old_locus_tag="EES43_26580"
     CDS             17221..18240
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="EES43_RS26935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26580"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_124272170.1"
                     /sec_met_domain="PF04055 (E-value: 3.9e-16, bitscore: 58.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.9e-08, bitscore: 32.5,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLAEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAMKEAKRLGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRSRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMNDGYVP
                     TYRQLVEETDWSKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETVVGTR"
     gene            18369..19766
                     /locus_tag="EES43_RS26940"
                     /old_locus_tag="EES43_26585"
     CDS             18369..19766
                     /NRPS_PKS="Domain: Aminotran_3 (45-367). E-value: 6.4e-90.
                     Score: 293.5. Matches aSDomain:
                     nrpspksdomains_EES43_RS26940_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="EES43_RS26940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26585"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_124271158.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.8e-88, bitscore:
                     293.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDGGPEGFDLTRLLAERGAERYELHARHLNHQLPRMLHTIGFDR
                     VYERAEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDAQLADLTRFDCQP
                     LPGLLAEKLLGHTPHLDRVFFGNSGTEAVETALKFARYATGKPRILYCPHAFHGLTTGS
                     LSVNGESGFRDGFAPLLPDTPVALGDLDALRRELERGDVAALVVEPIQGKGVRAAPPGY
                     LRQAQELLHCHKALLIADEVQTGLGRTGDFFAYQHEEGVEPDLVCVAKALSGGYVPVGA
                     TLGKDWIFRRVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDEETVANARRTGDLLR
                     ERLAALVDRYELLHDVRGRGLMIGIEFGRPSSLKLRGRWTMLQAARKGLFAQMVVVPLL
                     QKHRILTQVSGDHLEVIKLIPPLVIGEPEVERFVAAFTAVMDDAHSGGGLMWDFGRTLV
                     KQAVANR"
     aSDomain        18504..19469
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS26940_Aminotran_3.1"
                     /evalue="6.40E-90"
                     /label="EES43_RS26940_Aminotran_3.1"
                     /locus_tag="EES43_RS26940"
                     /protein_end="367"
                     /protein_start="45"
                     /score="293.5"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DAQLADLTRFDCQPLPGLLAEKLLGHTPHLDRVFFGNSGTEAVETALKFARYATGKPRI
                     LYCPHAFHGLTTGSLSVNGESGFRDGFAPLLPDTPVALGDLDALRRELERGDVAALVVE
                     PIQGKGVRAAPPGYLRQAQELLHCHKALLIADEVQTGLGRTGDFFAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFRRVYSSMDRVLVHSASFGSNAQAMAAGLAVLAVMEDE
                     ETVANARRTGDLLRERLAALVDRYELLHDVRGRGLMIGIEF"
     misc_feature    19786..19799
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     gene            19831..20439
                     /locus_tag="EES43_RS26945"
                     /old_locus_tag="EES43_26590"
     CDS             19831..20439
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955416.1"
                     /locus_tag="EES43_RS26945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26590"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_124271159.1"
                     /transl_table=11
                     /translation="MNTPDEGVADDLPGVAPRLRDLRRGRGLTLETAAQRAGLSPAHLS
                     RLETGRRQPSLPMLLGLARIYGTTVSELLGEAPPEREAIVRGGGFEGAEADGWMYRRAG
                     GSGRAMQALRVRVPYGAQGDLVRVHPGEEWLYVMEGRLRIALGETVHDLEPGDSAHFDS
                     LTPHRIAALGRGGAELLFVHTLLQSPAAELCLGNAFHAR"
     misc_feature    complement(19853..19867)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            20510..20683
                     /locus_tag="EES43_RS30850"
                     /old_locus_tag="EES43_26595"
     CDS             20510..20683
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955417.1"
                     /locus_tag="EES43_RS30850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26595"
                     /product="DUF6126 family protein"
                     /protein_id="WP_164493286.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLSPRRRKNEDPQERRMPRGVVIRLFAYLVAGHVIAA
                     FLYLLFVVAGSK"
     gene            complement(20724..21536)
                     /locus_tag="EES43_RS26950"
                     /old_locus_tag="EES43_26600"
     CDS             complement(20724..21536)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964842.1"
                     /locus_tag="EES43_RS26950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26600"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_124271160.1"
                     /transl_table=11
                     /translation="MTQQVPQVPPTEAALTGVRNFRDVGGLPTSDGRRTAYGRLYRSGH
                     LAHATAEDAALLGGLGLHTVFDFRNEADHRLEGHDVELPGVRNVSIPLSDPADGAEFWR
                     LVRDGNIEQLRSVLADGKATERMIRMYRATVRDRTAEHSRVLHALAEDSVPALMHCAAG
                     KDRAGLSIAVALLAVGVEREAIEADYLKSNDPHRRYRVKRADMSEVGMSPEVIELLNPL
                     FAAEADYLAAAFATIEEVWGTTDRYLAEGLALAPATRERLRVRLLDEG"
     misc_feature    21792..21806
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     misc_feature    complement(21953..21967)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.09"
                     /tool="antismash"
     regulatory      21980..22137
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            22143..23081
                     /locus_tag="EES43_RS26955"
                     /old_locus_tag="EES43_26605"
     CDS             22143..23081
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128943.1"
                     /locus_tag="EES43_RS26955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26605"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_124271161.1"
                     /transl_table=11
                     /translation="MPAQGKHRRTKSGAISRGVLAAGTGGAVLALPLFAATGAHAAEKA
                     APAAKPAAAVAAAHSAPAAAKAAPKTYSVVAGDYLSKIAAEHRIDGGWQKLYQDNRDAV
                     GSNPSLIRPGLKLTLGAEASGSAAPSKTERSAPAPKAAPKAKAAPQAAEKPAAQADTVS
                     ADDSAETGASQATGSGWTTPVANGNVTTQYRASGSSWSSGYHTGSDFQASSGTPIRAIG
                     PGTVVSAGWSGSYGNEVVIKHEDGMYSQYAHQSSLSVSAGQTVTGGQQIGLSGSTGNST
                     GPHLHFEVRTGPSYGSDVDPVAYLRQQGVSL"
     misc_feature    complement(23149..23162)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     misc_feature    23161..23176
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.38"
                     /tool="antismash"
     misc_feature    complement(23214..23224)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            23244..24071
                     /locus_tag="EES43_RS26960"
                     /old_locus_tag="EES43_26610"
     CDS             23244..24071
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007449852.1"
                     /locus_tag="EES43_RS26960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26610"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_124271162.1"
                     /transl_table=11
                     /translation="MADASRTQQQHIIGSYAAIGDSFTEGVGDPGPDGTFVGWADRFAV
                     LLADRLPAPDAATSPADSPHGNFRYANLAVRGRLLDQIVAEQIPRAKELAPDLVTFCAG
                     GNDIIRPGTDPDDLAERFERAVADLTGAVGTVMVTTGFDTRGVPVLRHMRGKIATYNVH
                     LRAIADRYHCPVLDLWSLRSVQDRRAWDSDRLHLSPEGHTRVALRAAQVLGVDVPADPD
                     QPWPPQALRRPFEARRDNIQWAREYLVPWIGRRLRGESSGDHVEAKRPDLLPL"
     gene            complement(24139..25101)
                     /locus_tag="EES43_RS26965"
                     /old_locus_tag="EES43_26615"
     CDS             complement(24139..25101)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579673.1"
                     /locus_tag="EES43_RS26965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26615"
                     /product="STM4011 family radical SAM protein"
                     /protein_id="WP_124271163.1"
                     /transl_table=11
                     /translation="MDLTILYRGPLASCDYDCPYCPFAKRRDSRAQLTADREALERFTA
                     WAAAQTGDRLSVLFTPWGEGLVRSWYRRALTELSRLPHVRRVAVQTNLSGRTSWLADAD
                     RERIALWCTYHPGQTPFDRFLGRCRELSGLGIRFSVGVVGFEAHREEARRLRAALPEEV
                     YLWVNAAEGHTYTDEEARRWTELDPLFPYSRHPHRSAGLPCRTGESVISVDGDGTVRRC
                     HFVRAELGNLYDGSYRRALGPRACPLAVCDCHIGYVHLETLPLYDVFAGGVLERIPAAH
                     GDRAVDGLLAVPSPSRRTVPGLSADPVRPSGSARPSGSA"
     gene            complement(25110..26477)
                     /locus_tag="EES43_RS26970"
                     /old_locus_tag="EES43_26620"
     CDS             complement(25110..26477)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058004.1"
                     /locus_tag="EES43_RS26970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_26620"
                     /product="STM4012 family radical SAM protein"
                     /protein_id="WP_124271164.1"
                     /sec_met_domain="PF04055 (E-value: 2.7e-14, bitscore: 52.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITTALPAVRPYEGYVYAYPHKTAYRPLADRPALCDLWAAERKD
                     ALSLYLHIPFCEVRCGFCNLFTRIGAPQELTTRYLDALDRQATAVREALGDGGPVRFAA
                     AAFGGGTPTFLTAGELERLCDIAEKRMGADLRSAPLSVETSPATATADRLAVLADRGAT
                     RISIGVQSFVDAEARAAVRPQRRAEVEAALGRIRDAGAPVLNVDLIYGIDGQTERSWLA
                     SLDAALAWRPEELYLYPLYVRPLTGLHRLGPAAGPEAAAREEARWDEQRLRLYAAGRDH
                     LLERGYEQVSMRMFRRADAPQEGPGDYACQTDGMIGLGCGARSYTAGLHYSFDYAVDMR
                     EIRSIIDGFTATEDFSRAEVGRYVDAEEARRRHLLQSLLQAAGLETAAYRTRFGTDPCE
                     DFAAELGRFAERGWLDAGAPDGVLRLSPRGLAHSDAVGPALFSSGVRAAMAAYERK"
ORIGIN
        1 ccatccttcg ctttggtctc cggccttgag tgccgggccc ctcgagtccg gtcaagtctg
       61 ccgcacaaaa gccgcttgtc cgtacttcgg gctcgggcat gtcaggtcca ccgcgcaccg
      121 ccccgcggtc ctcgggcccc ggggccccgt ctcagtggca gagcttcgcc tcgtgctcgg
      181 catggccgct gggctccagc tggaaggtgc agtgctccac gtcgaagtgg ctgccgaggc
      241 agccctggag gtcgtgcagc agcttctcgt gcccgatcga gtcgagcatc tcctgccgca
      301 cgaccacgtg cgcggagagc accggcatcc cggaggtgat cgtccaggcg tgcaggtcgt
      361 ggacgtcgat gacgccgggc agctccgtga tgtgggcccg gacctcctcc atgtccacgc
      421 ccttgggcgc cgcctccagc agcacgttca gcgtctcgcg cagcagtttc accgtccggg
      481 ggacgatcat caggccgatc agcagcgagg cgaccgggtc cgcggcctgc cagcccgtgg
      541 ccatgatgat gcccgccgag accagcaccg tcaccgagcc gagggtgtcg gccagcacct
      601 ccaggtacgc gccccggacg ttcaggctgt cctgctggcc gcgggtcagc agcgagagcg
      661 agacgacgtt ggccaccagg ccgaccgcgg cgaacgcgat ggtcagaccg cccttggtgt
      721 cggccggtgt gatgaagcgc tcgaccgcct cgaagaccag gaagccgccg accccgagca
      781 gcagcaggca gttggccagc gccgccagga tctcggcgcg ggcgaagccg aaggtgcggt
      841 tgggtccggc cgggcggttg gcgaagtgga tggcgagcag ggccatgccg agccccagcg
      901 cgtcggtggc catatgggcg gcgtccgcga tcagggccag ggagtccgac agcacaccgc
      961 cgacgatctc catgaccatc acgctcaggg tgatgcccag cgcgatccgg agcctgccct
     1021 ggtacgcggc ggctgccgtg cccgtcggag gcgccccgcc gtgcgcgtgc ccgtggtcgt
     1081 ggccagcccc catgagaaac cccttcaggt cggtgccgcg agaccggggc gaaacgcccc
     1141 ggccaggcca gtgaactacg ggtggggggt atccggcaac acggcactga acaccgttgt
     1201 catctgctct gacctgcgga aacgttccgc aggtcagagc cgtggggtga tcaggaacgc
     1261 tgccgcgcgc gggcctcggg gtggtgcagg caccatccct cccacgccga ctccaccatc
     1321 tcgcgcacgc tccgccgggc cgtccagtcc agctccttcg acagccgcgc ggcggacgcc
     1381 accgccctcg gcgcgtcacc cggccggcgc ggctcgacca ccggatcggc gcggtggccg
     1441 gtcacctcgc cgatgaccgc ggtcagctcg cgcaccgaga cgccctcgcc ccggccgacg
     1501 ttcaccgtca ggtccccgcc cgcgcgctcg cgcagccccc gggcgacggc caggtgcgcc
     1561 tcggccaggt cggtgacgtg gatgtagtcg cggacgcagg tgccgtccgg cgtcggatag
     1621 tcgtcgccga agatccgcgg ggcctcgccc cgggtcagcc ggtcgaagac catcgggacg
     1681 atgttgaaga cgccggtgtc ggacagctcc ggagccgccg cccccgccac gttgaagtac
     1741 cgcaggcagg cggtcgacag accgtgcgcc ttgccggccg cccgcaccag ccactcgccc
     1801 gcgagcttcg tctccccgta cgggttgatc ggcaggcagg gcgtctcctc ggtgatcacg
     1861 tccacgtccg gcacgccgta caccgccgcc gaggacgaga agaggaagtc gcgcacaccg
     1921 gccgcgacga ccgcctccag caggacggcg agcccggcga cgttctcccg gtagtacagc
     1981 agcggcttct cgaccgattc gccgacctgc ttcttcgccg cgagatggat gacgccgctc
     2041 accccgtgcc cggtgagcac ccggtccagc agcgcccggt ccgaggcgga gccctccacg
     2101 agcgtgacgg actccggcag cctcgcggcg acgcccgtcg agcggtcgtc gagcaccacg
     2161 acctcttcgc ccgccgccac catggccctc gccacatgtg ccccgatgta tcccgctccg
     2221 cctgtgatca gccatgtcat ggctgccacc ctaagggcag ccccgggcgg ccccgccgtc
     2281 gcggtttgtg gcccgggcgg tcgatcgacg atgatgatcg cgcagcgggc cggcccgggc
     2341 ggatacgccc gaacggcgca caaacaggcg gtgaactcgg gcttctgttc atccgatagc
     2401 ctcagccgac atgccgccgg cccgtcctcg ggccgcgccg ccgtgcgtcg tccaccgtca
     2461 gtgccaagga gtgagttcga ctgtcgaccg ccatcctcac cggtctgccg gtccccggat
     2521 cgtcactcgc cgacgatctg cgctcgctgg gcttcgaggt gcagaccgcc gccgaccccg
     2581 gtgacgccgc ggcgctcctc gccgccgtcc ccgcgaacag ccgcgtcgca ctcgtcgacc
     2641 cgcgcttcgt cggccacgtc cacgcgctgc ggctcggtct gaccgacccc cgcttcccgg
     2701 ccgccgccgt ccccggcgcg ctcaccgccc agcccgaggc tcgcgccgcg ctgacgcgcg
     2761 ccctgcgacg caccggggcc gcggtgggcg ccggcgcacc cgccgtcgag cccgacgccg
     2821 acccgacgcc cgccgaccgc accgccccgg cacccgccga cggcaccgtc ccgggccgcg
     2881 tcgcggcggc actggaggcc gagggcgtcg acgtacggcg ccccgaactc ggctcgctca
     2941 ccgccgccgt gcccaccgac gacgaccagc gcgccgccgc ggcggccggc ctcgcctcgg
     3001 tggacggcga ggcggtacgg ctgcgcggcg cggtcaaggc ccacgacggc ttcttcacca
     3061 cgttctgcgt cagcccctac tcccgccaca tcgcccgctg gtgcgcccgc cgcggcctca
     3121 ccccgaacca ggtcaccacc gcctcgctga tcaccgccct cgtcgcggcc ggcagcgcgg
     3181 ccaccgggac ccgcgccggt tacgtcgccg ccggcatcct gctgctggtc tccttcgtcc
     3241 tggactgcac cgacggccag ctcgcccgct actccctcca gtactccacg atgggcgcct
     3301 ggctggacgc caccttcgac cgggccaagg agtacgcgta ctacgccggg ctcgccctcg
     3361 gcgcggcccg cggcggcgac gacgtctggg tcctcgcgct cggcgcgatg gtgctccagg
     3421 cgtgccgcca cgtcgtcgac ttctccttca acgaggcgaa ccacgacgcg gtcgccaaca
     3481 ccagccccac cgcggccctc tccgaccggc tcgacagcgt cggctggacg gtctggctgc
     3541 gccgcatgat cgtgctgccg atcggcgagc gctgggccat gatcgcggtc ctcaccgcgc
     3601 tcaccacccc gcgcgtcgtc ttctacgccc tgctcgtggg ctgcgccctg gccgcctgct
     3661 acaccacggc gggccggctg ctgcgttcgc tgacccgccg ggcccggcgc accgaccgcg
     3721 cggcccgggc cctggccgac ctcgccgact ccggccccct agcccaggcc gtcgccgccg
     3781 tcgccccggg gctccgcggc gcgttcacgg ccccggccgt cgccctgctc gcagcgctcg
     3841 tgatggccgg ctccgccctg ttcctcccgt acggcagtgc cctcaccgtc gtcgccgccg
     3901 ccctgtacgt cctgctctcc ggcctggccg tggcccgtcc gctcaagggc ccgctcgact
     3961 ggctggtgcc gccgttcttc cgggccgccg agtacggaac gatcctcgtg ctggccgccc
     4021 gcagcgacgt gccgcacgcc gttccggcgg ccttcgggct cgtctcggcc gtcgcctacc
     4081 atcactacga cacggtctac cgcatccgcg gcggcaccgg cgcgccgccc cggtggctgg
     4141 tgcgcgtcct cggcggacac gagggccgga ccgcgctggt ggtcgtcctc gccgccgtcc
     4201 tcacccacgc ctcaggtttc accacggcgc tcaccgtcct cgcggtggcc gtggctctgg
     4261 tggcgctcgt ggagtccatc cgcttctggg tgtcctcctc ggcccccgcc gtacacgacg
     4321 aaggagaact cgcatgatcg gcctcgtact ggcagccggt gcaggacgac gtctgcgccc
     4381 ctacacggac acgctgccca aggcgctcgt ccctgtcgac ggcgaccgga cggtcctcga
     4441 cctcacgctg gccaacttcg ccgaggtcgg cctcaccgag gtggcgatcg tcgtcggcta
     4501 ccgcaaggag gccgtctacg cccgcaaggc cgaactggag gcgacgtacg gcctctcgct
     4561 gacgctcatc gacaacgaca aggccgagga gtggaacaac gcctactccc tgtggtgcgc
     4621 ccgcgaggtg ctcaagcgcg gcgtgatcct cgccaacggc gacaccgtgc accccgtctc
     4681 cgtcgagaag accctcctgg acgcccgcgg caagggccag aagatcatcc tcgccctgga
     4741 caccgagaag tccctggccg acgaggagat gaaggtcatc accgcggagg gcaagggcgt
     4801 ccagcgcatc accaagctga tggacccgtc gaccgcgacc ggtgagtaca tcggcgtgac
     4861 cctcatcgag gccgaggccg ccgaggagct cgccgacgcg ctgaggacca cgttcgagcg
     4921 cgaccccgac ctctactacg aggacggcta ccaggagctc gtcaaccgcg gcttcaccgt
     4981 cgacgtcgcc cccatcggca ccgtgacctg ggtcgagatc gacaaccacg acgacctcgc
     5041 gaagggccgg gtcatcgcgt gccagtactg acccggctca ttccgtcccc cgtcgtcgtc
     5101 gacatccggc gcggcgccat ggacgatctg gcgggtctcc tggccgacca gcggatctcc
     5161 tcgtcgggca agctcgccat cgcgatcagc gacggctcgg ggcgcgccct gcgcgagagg
     5221 ctcgcaccgg tcctgcccgg agccgactgg tactccgtct ccgacggcac gatcgactcc
     5281 gcggtgaaac tggccgacgg catcaagggc aaccgctacg acgccgtggt cggactcggc
     5341 ggcggaaaga tcatcgacgt ggcgaagtac gccgcggcgc gggtcggcct gccgctggtc
     5401 gccgtcgcca cgaacctctc gcacgacggc ctgtgctcgc cggtcgccac gctggacaac
     5461 gacaacgggc gcggctcgta cggcgtgccc accccgatcg ccgtggtcat cgacctcgac
     5521 gtcatccgcg aggcgccggc ccgctacgtc cgctccggca tcggcgacgc catctcgaac
     5581 atctcctgcg tcgcggactg ggagctggcg cacgaggtca acggcgagga gatcgacgga
     5641 ctggccgccg ccatggcccg gcaggccggc gaggccgtgc tgcgccaccc cggcggggtc
     5701 ggcgacgacg ccttcctcaa ggtgctggcc gagggcctgg tgctgaccgg catctccatg
     5761 tcggtcgcgg gcgactcgcg acccgcgtcg ggcgcctgcc acgagatcaa ccacgccttc
     5821 gacctgctct acccgcagcg cgcggccagc cacggcgaac aggtcggcct cggagcctgc
     5881 ttcgccatgc atctgcgcgg cgcccgtcag gagtccctcc tgatggcgtc gatactgcgc
     5941 cgccacggtc tgccggtcgt gccggaggag atcggcttca gcgtcgacga gttcgtccgg
     6001 gccgtcgact acgcgccgca gacgcgtccg ggacgtttca cgatcctgga gcacctcaac
     6061 ctgtccaccg accagatcag ggacgcgtac gccgactatg ccaagaccat cagtagctga
     6121 actccggccg gtcgtccacc cgccgggcgt gaaggaccgg cgcagcggcg agcactgggc
     6181 cgggcgcctg tacatgcggg aggtctcgct gcgcgtggac cgctacctgg tcgacacgcg
     6241 cgtcacgccc aaccagctga cctacgtgat gaccgtggcc ggggtgctgg cggctccggc
     6301 cctgctggtg ccgggcatcg gcggcgcgct gctcggcgtg ctgatggtcc agctctacct
     6361 gctgttcgac tgcgtcgacg gcgagatcgc ccgctggaag aagcagtact cgctcagcgg
     6421 cgtctacctg gaccgggtcg ccgcctacct gtgcgacgcg gcggtgctcg tcggcctcgg
     6481 cctgcgcgcc gccgacctgt ggggccaggg ccggatcgac tggctgtggg ccttcctggg
     6541 cacgctcgcc gccctcggcg cgatcctgat caaggccgag acggacctgg tcggcgtggc
     6601 ccgccaccag ggcggcatgc cgcccgtgca ggagtcggcg tccgagccgc gctcctcggg
     6661 catggccctg gcccgccgtg cggcaggcgc gctgaagttc caccggctga tcctgggcat
     6721 cgaggcgtcc ttcgtcatcc ttctggccgc cgtcctggac acgatcggcg gcgacctctt
     6781 ctacacccgc ctcaccacgg ccgtcatggc cggcatcgcc ctgctccaga cgctgctcca
     6841 cctggtgtcg gtcctggcgt ccagcaggct gaagtgagtc ctcccctgaa gctcggcgcg
     6901 gtgatcatca ccatgggcaa ccgccccgac gagctccggg ccctcctcga ttcggtcgcc
     6961 gcgcaggacg gcgaccggat cgaggtggtc gtcgtcggca acggcgcccc ggtcccggac
     7021 gtcccggccg gagtgcgcac ggtcgaactg cccgagaacc tgggcatccc cggcggacgc
     7081 aacgtcggta tcgaggcgtt cggcccgtcc ggggccgacg tggacggcct gctcttcctg
     7141 gacgacgacg ggctcctgcc gaaccgggac accgccgagc tgtgccggcg ggccttcgag
     7201 gcggacccgc ggctcgggat catcaccttc cggatcgccg acccggacac cggcaccacc
     7261 cagcgccggc acgtgccgag gctgcgcgcg gccgacccga tgcgctcatc gcgcgtgacg
     7321 actttcctcg gcggcgccaa cgccgtacgc acccgggtcc tcgccgaggt cggcgggctg
     7381 ccggacgcgt tcttctacgc gcacgaggag acggacctgg cctggcgggc gctggacgcg
     7441 ggctggatga tcgactaccg cgcggacatg gtgctgcacc atcccaccac cgcgccgtcc
     7501 cggcacgccg tctaccaccg catggtggcc cgcaaccggg tctggctcgc ccgccggaac
     7561 ctgcccgccg cgctggtccc cctctacgtc ggcagctggc tgctgctgac cctgctgcgc
     7621 cgcccgtcgc ctcccgcgct cagggcgtgg ttcggcggct tcagggaagg ctggtccgcg
     7681 ccctgcgggc cgcgccgccc catgaagtgg cgtacggtgt ggcggctgac gaggctgggc
     7741 cgacctccgg tcatctgaga cgcttacctc tgagagcatg aggcgtattt tctttccggg
     7801 acctgtccgc ctgagccgcg cccccgactg gccgcgcgtg aagacgagag tttcaacttg
     7861 tgagtgacac gacccacgac ggtggggtag ccctcggcac cctgtcgtcc gccgacgagg
     7921 ggctgagcgc ggcccagacg gccgccaagt acggcctgac cgtgagcggc gcccggccag
     7981 ggctgctcgc gtacatgcga cagctctggg gccggcgcca cttcatcctg gccttctcgc
     8041 gggcgaagct gaccgcgcag tacagccagg ccaagctggg ccagttgtgg caggtggtca
     8101 cgcccctgct gaacgccctg gtctactacc tgatcttcgg cctgatcctg gggaccaggg
     8161 aggggattcc caacgacgtc ttcgtgccgt tcctggtcac cggagtcttc gtcttcacct
     8221 tcacccagag ctccgtcatg gcgggcgtcc ggtcgatctc cggcaacctc ggactggtgc
     8281 gggccctcca cttcccccgg gcatcgctcc ccatctcctt ctcgctccag cagctccagc
     8341 agctgctctt ctcgatgatc gtgctggtcg cggtcgccgt catcttcggc agctacccct
     8401 cgctgtcgtg gctgctggtg atccccgcgc tggtcctcca gttcttcttc aacaccggcc
     8461 tggcgctcat catggcccgg ctcggcagca agaccccgga cctggcccag ctgatgccgt
     8521 tcgtcatgcg gacctggatg tacgcctcgg gcgtcatgtt ctccatcccg gtgatgctgc
     8581 gggacaagcc ggcgtggatc gccgacgtgc tccagtacaa cccggcggcc atctacatgg
     8641 acctggtccg cttcgccatg atcgacgggt acggctcgga gaacctgccg gcccacgtct
     8701 gggccgtcgg cgcgctgtgg gccgtgctgc tgggggtcgt gggattcgtg tacttctgga
     8761 aggcggagga gcggtacggc cgtggctgag gacaacacgc agggacggat tcccacggtc
     8821 atcgcggacg atgtccacat cgtctaccgg gtcaacggca cgggcggcgg tcgcggcagc
     8881 gccaccgccg cgctgagccg catcgtgaga cgcggcaagg gcgagtcgcg cggcgtcagg
     8941 acggtgcacg ccgtgcgcgg cgtctccttc accgcctacc gcggcgaggc catcgggctc
     9001 atcggcacca acggctcggg caagtcgacg ctgctgcggg ccatcgccgg cctgctgccc
     9061 acggagtcgg gccacgtcta cacggacggc cagccctccc tgctcggcgt gaacgcggcg
     9121 ctgatgagcg acctgaccgg tgagcgcaac gtggtgctcg gcggtctcgc catgggcatg
     9181 agccgggacg agatccgcga gcgctaccgc gagatcgtcg acttctccgg gatcaacgag
     9241 aagggcgact tcatcacgct gccgatgcgg acgtactcct ccggcatggc ggcgcggctg
     9301 cggttctcca tcgccgccgc caagaaccac gacgtcctca tgatcgacga ggcgctggcc
     9361 accggcgacc gcaagttccg ggtccgctcc gagcagcgga tccgcgagct ccgcaaggag
     9421 gcgggcacgg tcttcctggt cagccacaac aacaagtcca tccgcgacac ctgcgaccgg
     9481 gcgctgtggc tggagaaggg cgagctcctg atggacggcc ccaccgacga ggtgctcaag
     9541 gcgtacgagc gcgagacggg gaagtagccc gcaccgcatc ccgtggcctt cgccggatcc
     9601 tccggcggag gccacagcgg tgtgcgaggc cctggagcgg tgcgggggag agccctgcgc
     9661 ggtacgggcc gggaggcgat ctcctcccgg cggatgacgt caacgcacct acccacgggg
     9721 agagttggcc gaagaggcgg tgccggccgc cgggggtgct ccaccccggc gaggtccggt
     9781 cggccgtaca acgtaggctg tagcggtgct gattcatggc aagtggggcg atacgccccc
     9841 ggcgcttcgc ccgctgtgcc gcagtgcact cggaagaacg agcggcgtgt ccgaaaaggg
     9901 atgttttggg tcagcagtgt agaacgggag atgtgacggc aatgacggaa gatctccagc
     9961 tccgacgtgg tttcgccgtc cccgcgccgg gcggtccgca gtgacctcca gccggcaggc
    10021 gcgcaccggt gacgccacgc tcgacaaggc cgcggacgag aacttccccg tggccccctt
    10081 cttcctgccc cgcgcctggc gcggggacct catggcggtc tacggatacg cccggctggt
    10141 cgacgacatc ggcgacggcg acctcgcccc cggcggcgcc gacgcccgcc acctcggcct
    10201 ggagcctgag cagagcgagg accgcctcgc catgctcgac gccttcgaga ccgatctgca
    10261 ccgggtcttc gccgccaccg gggagccgca ccacccgctg ctgcgcgccc tgcgccccac
    10321 cgtgcggcgg cgcgcgctca cgcccgagcc cttcctcggg ctgatcgagg ccaaccggca
    10381 ggaccagaag gtccgccgct acgcgaccta cgcggagctc gccgcctact gcgagctctc
    10441 cgccaacccg gtcggccgcc tggtcctggc cctcaccggc accaccagcc cggaacgcgt
    10501 gcgccgatcc gacgcggtct gcaccgcgct ccagatcgtc gagcacctcc aggacgtggc
    10561 cgaggacctg gggcgcgacc ggatctacct gcccgccgag gacatggacc gcttccgtgt
    10621 caccgaatcc gacctggccg caccgtccgc cggcgcctcc gtccgcgccc tgaccgcgta
    10681 cgaggccgaa cgcgcgcacg agctgctgaa tgaaggcgcc cccttggtgg gtagcgtcaa
    10741 cggcaggctc aagctgctcc tcgcgggatt cgtcgccggc gggcgttccg cgctcacggc
    10801 gatctcggcc gccgggttcg acgtactgcc cggaccgccc aagcccacca agcccagcct
    10861 gctgcgcgaa gtgggagtcg tcttgcgaag agcgcgtgga gaggggtgag ccggaccgtg
    10921 gagggaccaa cgacgcacat gtcgccgccg gtgcaggccg catacagcta ctgcgaggcc
    10981 gtcaccggac agcaggcccg gaacttcgcc tacggcatca gactgctgcc gaacgagaag
    11041 cggcaggcca tgtcggcgct gtacgccttc tcccgccggg tcgacgacat cggcgacggc
    11101 gagctggacc cggagaccaa gcggacgcgg ttggagagca cccgccgact gctcgaccgg
    11161 gtgcgggccg gcgcggtcga cgaggacgac accgacccgg tggccgtcgc cctcaccgac
    11221 gccgcccggc gcttcccgct gccgctcggt ggactcgacg agctgatcga cggcgtcctc
    11281 atggacgtgc gcggcgcgac gtacgagacc tgggaggacc tgaaggtcta ctgccggtgc
    11341 gtcgcgggcg cgatcggccg cctcagcctc ggcgtcttcg gcacggaagc gggcgcgccc
    11401 ggcgccgaac gggcggcgga gtacgccgac accctcggcc tcgccctcca gctcaccaac
    11461 atcctgcgcg acgtccgcga ggacgccgcg aacgggcgca cctacctgcc cgccgacgac
    11521 ctggcgaagt tcggctgctc cgccgggttc caccgggcca ccccgccgcc cggctccgac
    11581 ttcgccggac tcgtccactt cgaggtgcgc cgggcccgcg cgctgttcgc cgagggatac
    11641 cggctgctgc ccatgctcga ccgccgcagc ggcgcgtgcg tcgccgccat ggcgggcatc
    11701 taccgccgcc tgctggaccg catcgagcgc gaccccgagg ccgtgctgcg cggccgggtc
    11761 tcgctgcccg gccacgagaa ggcgtacgtc gcggtgcgcg gcctgtcggg cctcgacgcg
    11821 cgccacgtct cgcggctcac cgcccggggg cggggctgat gcgccgagac cgccgcggcc
    11881 cggccgcgac cctccggtgg cccgacacgt cggcgactgc gacgatcttc atgacatccg
    11941 cgaccgcggc ggtcctcacg gtggcgaccc ggcgagaggg gcaggcatga gcgacgagac
    12001 accgcgcccc ggcgcggtcg tcgtcggcgg gggcctcgcc ggcgtcacgg cggccctccg
    12061 cctcgccgac gcggggctcg acgtcaccct gctcgaaggc cggccccgcc tgggcggcct
    12121 cgccttctcc ttccagcgcg gcgacctgac cgtggacaac ggccagcacg tctacctgcg
    12181 ctgctgcacc ggctaccgct ggttcctcga ccgcgtcgac ggggcccacc tcgctcccct
    12241 ccaggaccgc ctggacgtcc ccgtactgga cgtcggccgc cccgccggac cgcgcctggg
    12301 acgcctgcgg cgcaccggac tgcccgtgcc gctgcacctc gccggcgggc tcgcggccta
    12361 tccgcacctc tccctcgccg agaaggcggg cgtcggccgc gccgcgctcg cgctcggccg
    12421 cctcgacctg gcggacccgg agctcgaccg catcgacttc gccacctggc tgcgccggca
    12481 cggccagtcg cgacgcgccg tcgaggccct gtgggacctc gtcggcgtcg ccacgctgaa
    12541 cgccacggcc gccgacgcct ccctggccct ggccgccaag gtcttcaaga ccggcctgct
    12601 ctccgagccc ggcgccgccg acatcgggtg ggcctccgtg ccgctcggcg aactgcacga
    12661 caccctcgcc cgcaaggccc tggacaccgc cggcgtacgg accgagctcc gcgccaaggc
    12721 cggatccgtg acccgtacgg ccgacgggcg ctggagcgtc gagacggcgg gggagcggat
    12781 ccccgccgac accgtggtgc tcgccgtccc gcagaccgag acgcacgacc tgctgcccga
    12841 cggcgcgctc gacgaaccgg acctgctcct cgacatcgac accgcgccca tcctgaacgt
    12901 gcacgtgatc tacgaccgca aggtgctgcg ccgccccttc ttcgccgcca tcggctcgcc
    12961 cgtccagtgg gtcttcgacc gcaccgagtc ctccgggctc accggcccgg ggcagtatct
    13021 ggcggtctcc cagtccgccg cgagggacga gatcgacctc cccgtggccg aactgcgcac
    13081 gcgctacctg cccgagctgg agaggctgct gcccgccgcc cgcggcgcgg gcgtgcgcga
    13141 cttcttcgtc acccgggagc gcaccgcgac cttcgcaccc gccccgggcg tcgggcggct
    13201 gcgccccggc ccccgcaccc ggatgcccgg cctccagctg gcgggcgcct ggaccgccac
    13261 cggctggccc gcgacgatgg agggcgcggt gcgcagtggt ctcagcgccg ccgacgcggc
    13321 tctgaaggac ctcggccggc cccatggaca tccgctgcag gaggcggcat gagcagtacc
    13381 accggaacaa gaggagagtc agtgaccccg gcgaatccgg ctttcgacac cgtggcggac
    13441 accacggacg tcaccgcgct tctggagcgc ggacgagccc tgtcagcgcc ggtgctgcgg
    13501 gctgccgtgg accggctcgc gccgcccatg gacaccgtcg ccgcctacca cttcggctgg
    13561 atcgacgccg acgggcgtcc cgcggacggc gacggcggca aggccgtgcg ccccgccctg
    13621 gccctgctgt ccgccgaggc ggcgggcgcc ccggcggagg ccggcgtccc cggagcggtg
    13681 gccgtcgaac tcgtgcacaa cttctcgctg ctgcacgacg acctgatgga cggcgacgag
    13741 cagcgccgcc accgcgacac cgtctggaag gtgcacggcc ccgcccaggc gatcctcgtc
    13801 ggcgacgcgc tgttcgcgct ggccaacgag atcctgctgg agctcggcac cgtcgaggcg
    13861 ggccgcgcgg cccgccggct gaccaccgcc acccgcaagc tcatcgacgg gcaggcccag
    13921 gacatctcct acgagcaccg cgagcgggtc accgtcgagg agtgcctgga gatggagggc
    13981 aacaagaccg gcgcgctgct ggcctgcgcc gtctccatcg gcgcggtgct cggcggcgcg
    14041 gacgaccgca ccgcggacgt cctggagtcc tacggacacc acctcgggct cgccttccag
    14101 gccgtcgacg acctgctcgg catctggggc gaccccgagt ccaccggcaa gcagacctgg
    14161 agcgacctgc gccagcgcaa gaagtccctg cccgtcgtcg cggcgctcgc cgcgggcggc
    14221 gacgcctccg aacggctcgg cgaactgctt gccgccgacg ccaagagcag cgacttcgac
    14281 agcttctccg aggaggagtt cgccgcccgc gcggcgctca tcgaggaggc gggcggtcgc
    14341 gagtggaccg cccaggaagc ccgtcgtcag cacgcggtcg ccatcgaggc gctgcacggt
    14401 gtcgacatgc cgcaccacgt gcgggcgcag ctcacggcgc tcgcggactt cgtcgtcgta
    14461 cgaaagagat gatcaccatt cgcatatgac tcgcagtcgc cggccggcgt ccgtttcggg
    14521 cgccggccga cggagacccc agcacagcag agaaccgact gcacgaaggg gaagccatga
    14581 cagcgacgac cgacggatcc accggggccg cgaaccttca cgcagccccg gcaggacatc
    14641 cgaccgacac gaccaccgcc gcggacgacg tactcgccgc cgcgcgacgg gccgcggaac
    14701 gctcggtgga gcacctcctc ggcaggcagg acgagcaggg ctggtggaag ggcgacctgg
    14761 ccaccaacgt caccatggac gccgaggacc tgctgctccg ccagttcctc ggcatccagg
    14821 accccgggac caccgaggcc gccgcccgct tcatccgcgg cgaacagctc ggcgacggca
    14881 cctggaacac cttctacggc ggacccgccg acctctccgc caccatcgag gcctacgtcg
    14941 ccctgcggct ggccggggac cgccccgacg ccccgcacat ggcgcgcgcc tccggctgga
    15001 tcagggaaca gggcggtatc gcggcggccc gcgtcttcac ccgcatctgg ctcgccctgt
    15061 tcggctggtg gaagtgggac gacctccccg aactgccgcc cgagctgatg ttcctcccca
    15121 agtgggtgcc gctcaacatc tacgacttcg gctgctgggc ccgccagacg atcgttccgc
    15181 tgaccatcgt ctccgcgaaa cgccccgtgc gccccgcgcc cttcgccctg gacgagctgc
    15241 acaccgaccc cgcccacccc aatccgccca ggaagcctgc cccggcggcc agttgggacg
    15301 ggttcttcca gcgcctggac aagggcctgc acctctacca caaggtcgcc ccgcgcccgc
    15361 tgcgccgcgt cgcgatgaac gcggcggccc gctggatcat cgagcgccag gagaacgacg
    15421 gctgctgggg cgggatccag ccgcccgccg tctactccgt catcgcgctc cacctgctgg
    15481 gctacgacct cgaccacccg gtgatgcggg ccggaatcgc ctcgctcgac cggttcgccg
    15541 tgcgtcgcga ggacggcgcc cgcatgatcg aggcgtgcca gtcgcccgtc tgggacacct
    15601 gcctggccac catcgcgctg gccgacggcg gactcagacc cgaccacccg gccctggtca
    15661 gggccgccga ctggatgctg gcagaggaga tcacccggcc cggcgactgg tcggtacgca
    15721 aaccggaact cgccccagga ggctgggcgt tcgagttcca caacgacaac tacccggaca
    15781 tcgacgacac cgcggaagtc gtcctcgcac tgcgccgggt gtgccacccc gacccggcca
    15841 ggctggaagc cgccatcgag cgcggcgtgc gctggaacct cgggatgcag tcccgcaacg
    15901 gagcctgggg cgccttcgac gcggacaaca ccagcccctt ccccaaccgc ctcccgttct
    15961 gcgacttcgg cgaggtcatc gacccgccgt cggccgacgt caccggccac gtcgtggaga
    16021 tgctggccgt cgaaggactc tccgcgcacc cgcgcacccg ggcgggcatc gactggctcc
    16081 tcgccgaaca ggccccctgc ggagcctggt tcgggcgctg gggcgtcaac tacgtatacg
    16141 ggaccgggtc cgtggtgccc gccctgatcg cggccggcct gcccgccggt cacccggcga
    16201 tccgccgggc cgtcatctgg ctggagaccg tccagaacga cgacggcggc tggggcgagg
    16261 acctgcgctc gtaccgcgag gagaagtgga tcggccacgg cgagtccacc gcctcccaga
    16321 ccgcgtgggc gctgctcgcc ctcctcgccg ccggccgccg cgacacccgc gccgcagccc
    16381 gcggcgtcac ctggctgacc gacgcccagc aggccgacgg ctcctgggac gagccgtact
    16441 tcaccggcac cggcttcccg tgggacttct ccatcaacta ccacctctac cggcaggtct
    16501 tcccgctcac ggccctcggc cgctacgtcc acggcgaccc cttcgccgac cgcgcggatg
    16561 ctcgcgaggg ggcctgatgg gcgatgatcc gggccccacg accccgctgc tcgtcgcctg
    16621 cgcgctcggg atcgagcagc tcgcgctgcg cagcggccgg ggcgccgcgg ggccggtacg
    16681 ggtgctgcgc accggcatgg gaccccgcgc cgccgaggcg gccgtgggcc gcctgctggg
    16741 ctccggcggg gtgctgggcg ccgccgtcgt cgcggccggt ttctgcgccg gcctcgcccc
    16801 gggcatgcac ccgggggacc tgatcgtcgc cgaggagacc cgggacgccg acggcgtcac
    16861 gccctgcgtg ggcaccggac tgctcgtcga cgccctcgcc agggccgttc ccgggcgcac
    16921 ggtgcacacc ggacggctca ccggctccga ccacgtcgtc cgcggccccg aacgcgccgc
    16981 gctgcgggcg gacggggcca tcgcggtgga catggagtcg gccgccaccc tccgcaccgc
    17041 cctgtgccac ggcccacgtc cggttgcggc cgtccgggtg gtcgtggacg ctccagagca
    17101 tgagctcgtc cgcatcggca cgttccgcgg tggaatatca gccttccgcg ttcttcgtgc
    17161 cgtccttccg gcattttacg aatggcacag atctttatcg ctccccagga ggtgagccag
    17221 atggccatgc cgctccgcca gaccatcaag gtcgcgacgt accttgccga acagaagctc
    17281 cgcaagcgtg agaagttccc gctgatcgtc gagctggagc cgttgttcgc ctgcaacctc
    17341 gcctgcgagg gctgcgggaa gatccagcac ccggcgggcg tcctcaagca gcgcatgccc
    17401 gtcgcccagg ccgtgggcgc ggtgctcgaa tccggtgcgc ccatggtgtc catcgccggc
    17461 ggcgagcccc tgatgcaccc gcagatcgac gagatcgtgc ggcagctggt ggcgaagagg
    17521 aaatacgtct tcctctgcac caacgccatg ctcatgcgca agaagctcga caagttcacc
    17581 ccgtcgccgt acttcgcctt cgccgtgcac atcgacggac tgcgcgagcg gcacgacgaa
    17641 tcggtcgcca aggaaggcgt cttcgacgaa gccgtcgccg cgatgaagga ggccaagcgg
    17701 ctgggcttcc gcgtcaccac caactccacg ttcttcaaca ccgacacccc gcagaccatc
    17761 atcgaggtcc tcaactacct caacgacgac ctcaaggtcg acgagatgat gatctcgccc
    17821 gcctacgcct acgagaaggc gcccgaccag gagcacttcc tgggcgtcga gcagacccgg
    17881 gagctgttca agaaggcgtt cgcgggcggc aaccggtcgc gctggcgcct caaccactcg
    17941 ccgctcttcc tggacttcct ggagggcaag gccgacttcc cgtgcacggc ctgggccatc
    18001 ccgaactact cgctcttcgg ctggcagcgc ccctgctacc tgatgaacga cggttacgtc
    18061 ccgacgtacc gtcagctcgt ggaggagacc gactggagca agtacggccg gggcaaggac
    18121 ccgcgctgcg ccaactgcat ggcgcactgc ggctacgagc ccacggcggt gctcgccacc
    18181 atgggctccc tgaaggaatc cctgcgcgcg gcgcgggaga ccgtcgtcgg cacccgatga
    18241 cgccgtgacc ggggcggagc cggctcaccg ggccttcccg ggcggccggt tccgccccgt
    18301 cgcaccgtgc cgctcccgcc gacgggcggg cggcggcccc aggcagacgc gaaggagaag
    18361 agcgggcgat gacggacggc ggaccggagg gcttcgacct gacacggctc ctcgcggagc
    18421 gcggggccga gcggtacgaa ctgcacgcgc gccacctcaa ccaccaactg ccccggatgc
    18481 tgcacaccat cggcttcgac cgggtctacg agcgcgccga gggcgcgtac ttctgggacg
    18541 ccgacggcaa cgactacctc gacatgctcg ccgggttcgg cgtgatgggc ctcggccggc
    18601 accacccggt cgtccgcaag gccctgcacg acgtcctcga cgcccagctc gccgacctca
    18661 cccgcttcga ctgccagccg ctgcccggac tgctcgccga gaagctgctc ggccacaccc
    18721 cgcacctgga ccgggtcttc ttcggcaaca gcggcacgga ggcggtcgag acggcgctga
    18781 agttcgcccg ctacgccacc gggaagccgc gcatcctcta ctgcccccac gccttccacg
    18841 gactgaccac cggctccctc tccgtcaacg gcgagagcgg cttccgcgac ggcttcgccc
    18901 cgctgctgcc cgacaccccg gtcgccctcg gcgacctgga cgccctgcgc cgcgagctgg
    18961 agcgcggcga cgtggccgcc ctggtggtcg agcccatcca ggggaagggc gtgcgggcgg
    19021 ccccgccggg gtacctgcgc caggcgcagg aactgctcca ctgccacaag gcgctgctga
    19081 tcgccgacga ggtgcagacc ggcctcggcc ggaccggcga cttcttcgcg taccagcacg
    19141 aggagggcgt cgagcccgac ctggtgtgcg tggccaaggc gctgtccggc ggctatgtcc
    19201 ccgtcggcgc gaccctcggc aaggactgga tcttccgccg ggtgtactcg tccatggacc
    19261 gcgtcctcgt ccactcggcg agcttcggct ccaacgccca ggccatggcc gccgggctcg
    19321 cggtgctggc ggtgatggag gacgaggaga ccgtcgcgaa cgcccgacgc accggcgacc
    19381 tgctgcgcga acggctggcc gcactggtgg accgctacga gctgctgcac gacgtgcgcg
    19441 gacgcgggct catgatcggc atcgagttcg ggcggccgtc ctcgctgaag ctccgcggcc
    19501 ggtggaccat gctccaggcg gcccgcaagg gactcttcgc acagatggtc gtggtgccgc
    19561 tgctccagaa gcaccgcatc ctcacccagg tctcgggcga ccacctcgaa gtgatcaagc
    19621 tgattccgcc gctggtcatc ggcgagccgg aggtcgaacg cttcgttgcg gcgttcacgg
    19681 cggtcatgga cgacgcgcac agcgggggcg ggctgatgtg ggacttcggc cgcacgctgg
    19741 tcaagcaggc cgtcgccaac cgctaagtgc ctcttttgcc tccgaggcaa gttatttgcc
    19801 tcggaggaaa gaagctggcc caatggaggc atgaacactc cggacgaagg ggtggccgac
    19861 gacctcccgg gcgtcgctcc ccgcctgcgc gatctgcgcc gagggcgcgg tctcaccctg
    19921 gagaccgctg cccagcgggc cggactgtcc ccggcccacc tctcccggct ggagacgggc
    19981 cgccggcagc cctcgctgcc gatgctgctc ggtctggccc gtatctacgg tacgacggtc
    20041 tccgagctcc tcggtgaggc gccccccgaa cgggaggcga tcgtccgcgg cggcggcttc
    20101 gagggcgcgg aggccgacgg ctggatgtac cgcagggccg gcggttccgg ccgcgccatg
    20161 caggcgctgc gggtccgcgt gccctacggg gcccagggcg acctggtgcg cgtacacccc
    20221 ggcgaggagt ggctgtacgt catggagggg cggttgcgga tcgcgctcgg ggagaccgtg
    20281 cacgacctgg agcccggaga cagcgcccac ttcgactccc tcaccccgca ccggatcgcg
    20341 gccctcggcc gcggcggcgc ggaactgctc ttcgtccaca ccctgctgca gagccccgcg
    20401 gccgagctgt gcctcggcaa cgccttccac gcgcgctgac cggatccccc ggcccccgcc
    20461 cgccgcaccc gacgtatcac cggccgcgag gccggcagag aggaccgtca tgtcggattc
    20521 cgagcactac gatccgctga gcccgcggcg ccgcaagaac gaggacccgc aggagcgccg
    20581 gatgccgagg ggcgtggtga tccgcctctt cgcctacctg gtggcagggc acgtgatcgc
    20641 ggccttcctc tacctgctgt tcgtcgtggc cggcagcaag tgagccgggc ggcccggacg
    20701 ccccgagacg tccgggtggg ccctcatccc tcgtcgagca ggcgcacccg caaccgctcc
    20761 cgggtcgccg gggccagcgc cagaccctcg gcgaggtagc ggtccgtggt cccccagacc
    20821 tcctcgatgg tcgcgaacgc cgccgcgagg tagtcggcct ccgccgcgaa gagcgggttc
    20881 aggagctcga tcacctccgg ggacattccc acctcggaca tgtccgcccg cttcacccgg
    20941 tagcggcggt gcgggtcgtt cgacttgagg tagtccgcct cgatcgcctc gcgctcgact
    21001 ccgaccgcga gcagcgcgac cgcgatcgac aggcccgcgc ggtccttgcc cgcggcgcag
    21061 tgcatcagcg cgggcacgct gtcctcggcc agcgcgtgca gtacgcggct gtgctcggcc
    21121 gtgcggtcgc ggaccgtcgc ccggtacatg cggatcatgc gctcggtcgc cttgccgtcc
    21181 gcgaggaccg agcgcagctg ctcgatgttc ccgtcgcgca ccagtcgcca gaactcggcc
    21241 ccgtcggcag gatccgagag cggaatgctg acattgcgga cgccgggcag ctcgacgtcg
    21301 tgcccttcga gccggtggtc ggcctcgttg cggaagtcga agaccgtgtg gaggccgaga
    21361 ccgccgagaa gggctgcgtc ctcggcggtg gcgtgcgcca ggtggccgct gcggtagagc
    21421 cggccgtacg cggtgcgccg cccgtcggag gtggggagcc cgcccacgtc gcggaagttg
    21481 cggactccgg tgagcgccgc ctcggtcggc ggaacctgcg gcacctgctg cgtcacggtg
    21541 tctcctgggg tctcgggcgt cggcgctgct cgccgtcgag ggcgctcccg tgacgatacg
    21601 acatcgattc agcggaaaat catctcggct gcgggcggtc atgtccggac gtcagcggac
    21661 cggactgaca ggccatcagg ggagatgtgc ctgccatgtc cgtattggtg catttagaag
    21721 aacatgccca aattatgggg gagatgggat cgagtgggtg agcgggatca tatccgtgac
    21781 ggaccgtggc gatcttgtcc ggcgatattc ccggcgctcg cacgaaaggc aagatccgta
    21841 atccacggag tgtgacggga aaagcgaagc ggaatcgaat cgacgaatac ggtacggaac
    21901 cggcggcttg ttcctgtcct cctgactcgc ttacggtcac cctcaatccg gacggaccgc
    21961 ctaatcctgc cgccgcccgg aattcccacc acccactcac gcgtggcagg agcgggggac
    22021 ccaggtaagc cgccggcccg gagcgatccg gaccggctcg gggtgaagtc gcgtccagcg
    22081 gccgggcatc tccagcccga acccgacagc tcacctcgca ggcgccggag aggaacaacc
    22141 ccatgcccgc acagggtaag caccgtcgta ccaagtccgg cgcgatctcc cgcggcgtcc
    22201 tcgccgccgg aaccggaggc gccgtactcg ccctgccgct gttcgccgcc accggcgcgc
    22261 acgccgcgga gaaggcggcc ccggccgcca agcccgccgc cgcggtggcc gccgcgcact
    22321 ccgctcccgc cgcggcgaag gccgcgccga agacgtactc cgtcgtcgcc ggagactacc
    22381 tgtccaagat cgccgccgag caccgcatcg acggcggctg gcagaagctg taccaggaca
    22441 accgcgacgc cgtcggctcg aacccgagcc tgatccgccc cggcctgaag ctgacgctcg
    22501 gcgccgaggc gtccggctcc gccgcgccct cgaagacgga gcgttccgcg cccgccccca
    22561 aggccgcccc gaaggcgaag gccgctccgc aggccgccga gaagccggcc gcccaggcgg
    22621 acacggtctc cgccgacgac tccgccgaga ccggcgcctc ccaggccacc ggctccggct
    22681 ggaccacccc ggtcgccaac ggcaacgtca ccacccagta ccgcgcttcg ggctccagct
    22741 ggtccagcgg ttaccacacc ggctcggact tccaggcgtc ctccggcacg cccatccgcg
    22801 ccatcggccc gggcaccgtc gtctcggccg gctggagcgg ctcgtacggc aacgaggtcg
    22861 tcatcaagca cgaggacggc atgtactccc agtacgccca ccagtcctcg ctgagcgtct
    22921 ccgccggcca gaccgtgacc ggcggccagc agatcggcct ctccggctcc accggcaact
    22981 cgaccggccc gcacctccac ttcgaggtcc gcaccggacc gagctacggc tcggacgtcg
    23041 acccggtcgc ctacctccgc cagcagggcg tctccctctg agccgacggc ggtagcgagg
    23101 gtatgagggg cggtgcgcgg cggcgcaccg cccctccact tattccggct ttaccaaaaa
    23161 ctgaccgggt ggtctatctc accatccgtc aaccccgtat tacggtcgcg taggtcacat
    23221 tgaacggtgc aggatatgcg cttgtggcag acgcatcgag aacccagcag cagcacatca
    23281 tcgggtcgta cgcggcgatc ggcgacagtt tcaccgaagg agtcggcgac cccggccccg
    23341 acggaacctt tgtcggctgg gcggaccggt tcgcggtcct gctcgcggac cggctcccgg
    23401 cccccgacgc cgcgacgagc ccggcggact ccccgcacgg gaacttccgc tacgccaacc
    23461 tcgccgtacg cggacggctc ctcgaccaga tcgtggcgga gcagatcccc cgggccaagg
    23521 agctcgcccc cgacctggtc accttctgcg ccggcggcaa cgacatcatt cggcccggca
    23581 ccgaccccga cgacctggcc gagcgcttcg aacgggcggt cgccgacctg acgggcgcgg
    23641 tcggcaccgt catggtcacc accggcttcg acacccgcgg tgtgcccgtg ctgcgccaca
    23701 tgcgcggcaa gatcgccacg tacaacgtcc acctgcgggc catcgccgac cgctaccact
    23761 gcccggtgct cgacctgtgg tcgctgcggt cggtccagga ccggcgcgcc tgggacagcg
    23821 accggctgca cctgtcgccc gaggggcaca cccgcgtggc gctccgggcc gcgcaggtcc
    23881 tcggcgtcga cgtgccggcc gaccccgacc agccctggcc cccgcaggcc ctccgccgtc
    23941 ccttcgaggc acggcgcgac aacatccagt gggcccgcga atacctcgtg ccctggatcg
    24001 ggcggcggct gcgcggagag tcctccggcg accacgtcga agccaagcgc ccggacctgc
    24061 tgcccctctg accccggccg acggcggcgc gggacccggg gtgccggacg ggacccgcgc
    24121 gtcaggcgga cccgggcttc aggcggaccc ggagggccgg gcggacccgg agggccggac
    24181 gggatccgcc gacagcccgg ggaccgtccg ccgggacggg ctcggaaccg ccaggagccc
    24241 gtccaccgcg cggtcgccgt gggccgccgg tatccgctcc aggacgccgc ccgcgaacac
    24301 gtcgtacaac ggcagcgtct ccaggtgcac ataaccgatg tggcagtcgc acacggccag
    24361 cggacaggcc cgcgggccga gcgcccggcg gtagctgccg tcgtacagat tgcccagctc
    24421 cgcccgcacg aagtggcagc ggcgcaccgt gccgtcgccg tcgaccgaga tcaccgactc
    24481 acccgtgcgg cagggcagac ccgccgaacg gtgcggatgg cggctgtagg ggaagagcgg
    24541 atccagctcc gtccaccgcc gtgcctcctc gtcggtgtac gtgtgcccct cggcggcgtt
    24601 cacccagagg tacacctcct cgggcagtgc cgcccgcagc cgccgcgcct cctcccgatg
    24661 ggcctcgaag cccaccacgc ccacgctgaa gcggatcccc agcccggaca gctcccggca
    24721 cctgcccagg aaccggtcga acggggtctg ccccgggtgg tacgtgcacc agagcgcgat
    24781 ccgctcccgg tcggcgtcgg ccagccacga cgtgcgcccg ctcagattcg tctggacggc
    24841 cacccggcgg acatgcggca gacgcgacag ctcggtcagc gcccgccggt accaggaccg
    24901 caccagcccc tcaccccacg gggtgaacag gaccgagagc cggtcgccgg tctgcgccgc
    24961 cgcccaggcg gtgaagcgct ccagcgcctc ccggtccgcc gtcagctgcg cccggctgtc
    25021 ccgcctcttg gcgaacgggc agtaggggca gtcgtagtcg cacgaggcga gcggcccccg
    25081 gtagaggatc gtgaggtcca cggccgccct cacttcctct cgtacgcggc catcgcggcc
    25141 cgcacaccgg aggagaacag ggccgggccg accgcgtccg agtgggccag gccccgcggc
    25201 gacagccgca gcacaccgtc cggcgccccg gcgtccagcc agccccgctc cgcgaaccgg
    25261 cccagctcgg cggcgaagtc ctcgcagggg tccgtgccga accgggtccg gtaggcggcc
    25321 gtctccaggc ccgccgcctg gagcagcgac tggagcagat ggcgcctgcg ggcctcctcc
    25381 gcgtccacgt accgtccgac ctcggcgcgg gagaagtcct cggtcgccgt gaagccgtcg
    25441 atgatggacc ggatctcccg catgtccacc gcgtagtcga acgagtagtg caggcccgcc
    25501 gtgtacgaac gggccccgca gcccagcccg atcatgccgt cggtctggca ggcgtagtcg
    25561 ccgggcccct cctgcggggc gtcggcgcgg cggaacatcc gcatcgacac ctgctcgtag
    25621 ccgcgctcca gcagatggtc ccggcccgcc gcgtacaacc gcagccgctg ctcgtcccac
    25681 cgcgcctcct cccgggccgc cgcctccggc ccggccgccg ggcccagccg gtgcagaccg
    25741 gtcagcgggc gcacgtacag cgggtagagg tacaactcct cgggccgcca ggccagcgcc
    25801 gcgtccagcg acgccagcca gctgcgctcc gtctgcccgt cgatcccgta gatcaggtcg
    25861 acgttcagca ccggggctcc ggcgtcccga atccggccga gcgccgcctc cacctcggcc
    25921 cgccgctgcg gccggacggc ggcccgcgcc tcggcgtcca cgaagctctg cacaccgatg
    25981 ctgatccgcg tggcgccccg gtcggccagc accgccagcc ggtcggccgt ggcggtggcc
    26041 ggggacgtct ccaccgacaa cggcgccgaa cgcagatcgg cgcccatccg cttctccgcg
    26101 atgtcgcaga gccgctccag ctcaccggcc gtcaggaacg tgggcgtgcc gccgccgaac
    26161 gccgccgccg cgaaccgcac cggtccgccg tcgcccagcg cctcccgtac cgccgtcgcc
    26221 tgccggtcga gcgcgtcgag atagcgcgtc gtcagctcct gcggcgcgcc gatccgggtg
    26281 aagaggttgc agaacccgca gcgcacctcg cagaacggta tgtggagata gagggacagc
    26341 gcgtccttgc gctccgccgc ccacagatcg cacagcgcgg gccggtccgc cagcggccgg
    26401 tacgccgtct tgtgcggata ggcgtacaca tagccctcgt acggccggac ggcgggaaga
    26461 gcggtcgtga tggtcatcgg gggtcctccg gttcgaggaa gaagtgggcg tacggcacgg
    26521 tccagacggc ttcgtgaccg agccggtgac cggtgtaccc gccgtcgccg taggcgg
//
