LOCUS       NZ_ML123034            21047 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4586034
            Orig. end                         :: 4607081
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..21047
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21047
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21047
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11047](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11047
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    324..338
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    417..426
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(930..1343)
                     /locus_tag="EES43_RS20365"
                     /old_locus_tag="EES43_20060"
     CDS             complement(930..1343)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="EES43_RS20365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20060"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_003966375.1"
                     /transl_table=11
                     /translation="MSQIAGEPGNQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGRAPERDTFAWTV
                     LSALAGKVDSTVADDRTVSISLYKQRGAGPGPA"
     gene            complement(1575..1835)
                     /locus_tag="EES43_RS20370"
                     /old_locus_tag="EES43_20065"
     CDS             complement(1575..1835)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966374.1"
                     /locus_tag="EES43_RS20370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20065"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_124270035.1"
                     /transl_table=11
                     /translation="MSDCAHVSELPRPEPVPLGETCPECLAAGTHPVQLRLCLTCGHVG
                     CCDSSPLRHATGHHRETGHPVMRSFEPGESWRWCFEDGSIV"
     gene            1871..3472
                     /locus_tag="EES43_RS20375"
                     /old_locus_tag="EES43_20070"
     CDS             1871..3472
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510032.1"
                     /locus_tag="EES43_RS20375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20070"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_124270036.1"
                     /transl_table=11
                     /translation="MDALPLVGLVAASAAVAGAARRTPVPAPLVLVAAGLVAGYLPGVP
                     TYTLDAHVVLPLLLPPLLYTAAVDSSYLDLRANVRPVALLSVGYTLFATIAVGWLAYLI
                     IPDLPLTAALVLGAVIAPPDAVTAAAIARRVGLPARVTTILQGESLVNDATAITAFKVL
                     VAAAVGAGVSWGAGIGEFLLAAFGGIGVGLLLMVPLHWLRTHLQEALLQNTLSLLIPFV
                     AYAAAERVHASGVLAVVVVALYLGHRSWQVDFATRLQEAAVWKMVAFVLESAVFALIGL
                     QLPFVLRGLGAFGVAEALWYAVFVFIAVVVVRFAWVYPATFLPRWASRRIREREPGTDW
                     TAPLIVGWAGMRGVVSLAVAFSIPLVRHDGEPFPARNLVLFLTFTTVIGTLVIQGLTLP
                     ALVRVLRLPGSDPKAETLVEAQAQSEASAAAEDRLEELLADPHSNLPPPLADRLRGTLE
                     RRRNAVWERLGTSDPVTGESADDTYRRLARAMIAAEREVFVRLRDERRIDDEMLRTLLR
                     RLDLEEAAAYRETDDS"
     gene            complement(3448..4404)
                     /locus_tag="EES43_RS20380"
                     /old_locus_tag="EES43_20075"
     CDS             complement(3448..4404)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379092.1"
                     /locus_tag="EES43_RS20380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20075"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_241192484.1"
                     /sec_met_domain="PALP (E-value: 1.5e-12, bitscore: 46.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPVDLARALQPQPPSPLQEVRDDRFARRGVRLLLKRDDLIHFT
                     PDWDTAALGPAELYPPGNKWRKLAPNLRAAAGRTVLTFGGAYSNHLRATAAAGRLLGFP
                     TVGVVRGDELARRPLNPSLARCAADGMRLHFVDRASYRAKDSPEVLAGLLERFGDVEVV
                     PEGGSNALAARGCAALGRELRGLTEVAAVACGTGGTLAGLAAGLGPGQRALGVPVLRGG
                     FLGETVARLQREAFGGPAGSWSLEERFAFGGYARTTPELEAFAADFEDRHGLPVERVYV
                     AKLLFALTALAEEGGFPPGSRVTAVITGTLQESSVSR"
     gene            complement(4439..5170)
                     /locus_tag="EES43_RS20385"
                     /old_locus_tag="EES43_20080"
     CDS             complement(4439..5170)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018547456.1"
                     /locus_tag="EES43_RS20385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20080"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_164493209.1"
                     /transl_table=11
                     /translation="MEDAKLTPRKLATRIGVAPKTVERWLADAELLPHARNRVDACRAL
                     KVDEDMIWPKAVQERVKTGHDRELAHAYPYRSACPSTVWGELIAGASTDIFFAGYTNYF
                     VWLEQPAFIETLRRKIASGCRVRFLLGDPDGEVTRQREAIEDVALSVGTRIRISLEHLG
                     RLGPLDGLETRFSSPEDAVNHVSLSVFRFDHDALVTPHLARLVGHDSPLLHLRRQEDSG
                     MFDRFAEHAEELWDRGVPQTP"
     misc_feature    complement(5075..5077)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6168..6182
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            complement(<6389..6529)
                     /locus_tag="EES43_RS31470"
                     /pseudo=""
     CDS             complement(<6389..6529)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048268.1"
                     /locus_tag="EES43_RS31470"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="1-aminocyclopropane-1-carboxylate deaminase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHHEPRGSAGLRPVLPSPLHSVRDERFDRSGVSLLLKRDDLVHPE
                     LP"
     misc_feature    6531..6547
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.13"
                     /tool="antismash"
     gene            complement(6555..7751)
                     /locus_tag="EES43_RS20400"
                     /old_locus_tag="EES43_20085"
     CDS             complement(6555..7751)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741535.1"
                     /locus_tag="EES43_RS20400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20085"
                     /product="globin domain-containing protein"
                     /protein_id="WP_124270038.1"
                     /transl_table=11
                     /translation="MLSERSTATVRATLPAVGAAIGDIADLFYRKLFAAHPELLRDLFN
                     RGNQASGDQRRALAGSIAAFASQLVERPDTRPDVMLNRIANKHASLGVTPAQYEVVHTH
                     LFAAIADVLGDAVTPEVAAAWDEVYWLMAGGLIAAEARLYAQRGVVAGDVWRTWEVVGR
                     VEETPDVATFRLRPADGSPAPAFRPGQYVSVQLELADGSRQIRQYSLSSSPGSPLRSIT
                     VKHVRADGTPDGEVSQRLHTHVRPGDRLRLSAPYGDLVLDHLDAPLLLASAGIGCTPML
                     SMLEHLAERGHRGPVSVVHGDRSPSDHALRADHARLTAELEDAAAHFWYERPEPGHPAE
                     RTGRVDLAAVTVLPGTHAYLCGPLPFMRDVRTRLLAEGVRPADVHYEVFGPDLWLAAG"
     misc_feature    7822..7840
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            complement(7882..8328)
                     /locus_tag="EES43_RS20405"
                     /old_locus_tag="EES43_20090"
     CDS             complement(7882..8328)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611275.1"
                     /locus_tag="EES43_RS20405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20090"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_124270039.1"
                     /transl_table=11
                     /translation="MRLTRFTDVALRVLMRLAVAEDGEPPTTREVAATMRVPYTHAAKT
                     VARLQHLGLLDARRGRGGGLTLTSAGHTASIGSLVRELEGTGDVVECEGETPCPLRSAC
                     RLRGALRQAQEAFYATLDPITVDDLVTAPTGPLLLGIGRGPETG"
     gene            8506..9909
                     /locus_tag="EES43_RS20410"
                     /old_locus_tag="EES43_20095"
     CDS             8506..9909
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966367.1"
                     /locus_tag="EES43_RS20410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20095"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_124270040.1"
                     /transl_table=11
                     /translation="MSVGEEVRDTQAPQQSLGTAAARNLATTTKSAPQMQEISSRWLLK
                     MLPWVQVQGGTYRVNRRLSYSVGDGRVTFVQTGDRVSVIPGELAELPALRDFGDEEVLA
                     ELSRRCEQRDVAAGEVLAASGDAADRVFLLAHGKVEKIGSGLYGDETELGVLADGAYFG
                     DRSLVDGDAVWEYTARAVTACTLLTLSRADVLNLAERAEPLRDHLAGLLSIPHQRTNRY
                     GEAEIDLSAGHVGEAVVPHTFVDYDASPREYELSVAQTVLKVHSRVADLYNQPMNQTEQ
                     QLRLTVEALRERQEHELINNREFGLLNNCDYGQRIQPHDGVPGPDDMDELLSRRRGSKL
                     FLAHPRAIAAFGRECNRRGLVPESVDVGGHHVPAWRGVPIFPSNKIPVTGARTTSIICM
                     RTGEAEQGVIGLQQTGIPDEIEPSLSVRFMGIDEQAIISYLVTAYYSAAILVPDALGVL
                     ENVEVSRWH"
     gene            10001..11047
                     /locus_tag="EES43_RS20415"
                     /old_locus_tag="EES43_20100"
     CDS             10001..11047
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959111.1"
                     /locus_tag="EES43_RS20415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20100"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_124270041.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.6e-60, bitscore:
                     202.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTDAAATEGHEAAALLEHTRAVVDPPLRAAVESLPAGIRRVAM
                     YHFGWENADGTPASGQAGKAIRPALVLAAARALGGDPEQAVRAAVAVELAHNFTLLHDD
                     VIDEDTTRRHRPTAWAVFGIPDAVITGDALLALAQQLLAEDPHPAAARAAARLSACVIE
                     LCAGQQTDCAFEERGPDEVTLDACLAMATAKTGALLGCACSLGALYAGAEDRVVGAMDG
                     FGREAGLSFQLIDDLIGIWGDPARTGKPVGADLSAHKKSLPVVAALTSGTPAAAELAAL
                     YRGELSAPAEVALAADCVDRAGGRDWAQAAAADRMARAVHHLSRAVPDPSAADDLLALA
                     EFVTRRTS"
     gene            11188..11856
                     /locus_tag="EES43_RS20420"
                     /old_locus_tag="EES43_20105"
     CDS             11188..11856
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959109.1"
                     /locus_tag="EES43_RS20420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20105"
                     /product="DUF6304 family protein"
                     /protein_id="WP_124270042.1"
                     /transl_table=11
                     /translation="MTDESWAGWYRDSKGSDAVVLTTDGVHLRIRIRGVDFEGESFDDL
                     GPVAGIPPESGMFALSGGALTDCVLEWDLPLPVLVEGSLRQATLSCLLSLRRVDPDLYL
                     ALHLDGAVYESARAESDFATALAAVQRLLPDGVRLQTCIACAFSDYFPAADRGLSGGLA
                     CFRGAKDAYRDTEGEDAVLDLWDRRTGFVQEIWSCREFEARPAEGAGTGHRGAFPLELA
                     "
     misc_feature    complement(11958..11968)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            12160..12849
                     /locus_tag="EES43_RS20425"
                     /old_locus_tag="EES43_20110"
     CDS             12160..12849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888484.1"
                     /locus_tag="EES43_RS20425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20110"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_124270043.1"
                     /transl_table=11
                     /translation="MAMARQDTDAGRALRALEDGRSSVRLRAALAVGTAPDPCFVGKLV
                     ERCAIEPEFFVRDMLTWALTRHPVSLTLPELLREVGSERARARSQALHTLSKIGDRQAW
                     PAITRALLCDTDDEVARSAWRAAVVLVPGGEEPSLAAVLATQLGRGGRETQLSLSQALV
                     ALGDVIVPVLDTATTVSDPQVRAHALATQGLLRDPDAGFASAVEEARRAVALTGAPGTD
                     DEDRADR"
     gene            12836..13834
                     /locus_tag="EES43_RS20430"
                     /old_locus_tag="EES43_20115"
     CDS             12836..13834
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070893.1"
                     /locus_tag="EES43_RS20430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20115"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_124270044.1"
                     /transl_table=11
                     /translation="MLIGEVSRRSGVSARMLRHYESLGLVRPSGRTGSGYREYSAEDIR
                     RIFHIESLRSLGLSLREVGRALDDPGFTPSALVGDLIRRTLDRIAAETDLLTQLRRIHA
                     ADPVGWADVLQTVALLQALGSTSADVRQRAVLSSGDEAPVEALVEAALSETEPSVAGAL
                     RWALARSDDGARALLAEGLGSPVAAVRERAVQALVELPGDGAAAQLRVALANSDAVVRG
                     YAAVALGTRGEAEAVPALLDMIVEGRNDTDAADALSVLASDTPTADRITTRLVDRLADG
                     ATEAPARGRLTQALADIPGTTASRALVELSHDEDPAVALTAAYLLQLRDTR"
     gene            14024..14995
                     /locus_tag="EES43_RS20435"
                     /old_locus_tag="EES43_20120"
     CDS             14024..14995
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061501.1"
                     /locus_tag="EES43_RS20435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20120"
                     /product="DUF1648 domain-containing protein"
                     /protein_id="WP_124270045.1"
                     /transl_table=11
                     /translation="MTRTNLDRVTLAALPFVLALLVDLVLFAVLKDRLPGRIASHFGVD
                     GAADGHVGRTAYVLATTPVLIVLGALWGLAAVRGKFHGRAHRRFLGAGWALAGFLGYLS
                     AAVLTVNADAPGGGPADRLPPGHLAAAVAVAVLAGALGLLAARAVPAPAAPSAYGDRAG
                     RGRIVLAEGEVAGWARSTGAWWLPLAAAALLAVGVVLGLRLSWFAGAPVLLLALPVLCF
                     CRPYVTVDRRGLTVSGLLPWPRVRVPLERIAAADSRRVDALAEYGGWGYRVRPGRTGFI
                     VRSGEAIVARQTGGRDFAVTVEDSATAAALLNTLVDRHRAGR"
     gene            14998..15354
                     /locus_tag="EES43_RS20440"
                     /old_locus_tag="EES43_20125"
     CDS             14998..15354
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458277.1"
                     /locus_tag="EES43_RS20440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20125"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_124270046.1"
                     /transl_table=11
                     /translation="MLFRVDPTSTVPLGDQVAASVRRAVADGTVTPGERLPAARILAES
                     LGVNVHTVLRGYQRLREEGLIELRRGRGAVVTAGASPHRARLLERVREVVADARDLGMT
                     EEELLLLVRAELSA"
     assembly_gap    15532..17028
                     /estimated_length=1497
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(17217..17882)
                     /gene="snpA"
                     /locus_tag="EES43_RS20445"
                     /old_locus_tag="EES43_20130"
     CDS             complement(17217..17882)
                     /EC_number="3.4.24.77"
                     /codon_start=1
                     /gene="snpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492104.1"
                     /locus_tag="EES43_RS20445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20130"
                     /product="snapalysin"
                     /protein_id="WP_124270047.1"
                     /transl_table=11
                     /translation="MRHLRTAFASAVAGLGLVAALGTAPAIAAAPAPAAPPAAAADVAG
                     YTASSTANERANRAFFDAVLKSVAEKQAAKPGVQAVTVVYDASQAPTFSSQIASSTQIW
                     NSSVSNVTLQEGSNADFTYREGNDPRGSYASTDGKGGGFIFLDYAQNQQYDATRVTTHE
                     TGHVLGLPDNYAGPCSELMSGGGPGTSCTNANPDANERAQVDSLWQNGFAAALAEATR"
     misc_feature    18092..18101
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            18153..19106
                     /locus_tag="EES43_RS20450"
                     /old_locus_tag="EES43_20135"
     CDS             18153..19106
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127501.1"
                     /locus_tag="EES43_RS20450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20135"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_124270048.1"
                     /transl_table=11
                     /translation="MELEVRHLRALCAIADAGSLHRAARRLGVSQPSLTTQLRRIENSL
                     GAELFRRERTGCRPTPLGRSVLSRARPLVDGMSALVNDALAEAEAARPRGPGLRIGSTA
                     SRVIGGWLRRLRVAMPGTDISLRVDVSAHALLRSVEAGRLDVAFVHEVEGSPLAVPEGL
                     EQRVLLDREPQFISLARTHPAARRRVVDLRDLAGDPWMVDPSVDGEWDGVRRMLGAAGL
                     NPPVLHGDYLTAASLVALGEAVALCQPTSGPRDDTVIRPLRDDPLAVRLLLVSRPGADM
                     AGVYAELEAAYREAARRSSGYHEWLLRHRSPLAHAA"
     gene            19165..19533
                     /locus_tag="EES43_RS20455"
                     /old_locus_tag="EES43_20140"
     CDS             19165..19533
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578699.1"
                     /locus_tag="EES43_RS20455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20140"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_124270049.1"
                     /transl_table=11
                     /translation="MTEPLLHLAEAPLWEAARGTGTYEMSTRGRTLQEEGFIHCSLPHQ
                     LPGVVRMLYGSDDRDLVVLVVDPARLTAPVRYEAMEPGGEEFPHVYGPLPVDAVVEVRP
                     WPASQAASEERREEGGAR"
     gene            19530..20408
                     /locus_tag="EES43_RS20460"
                     /old_locus_tag="EES43_20145"
     CDS             19530..20408
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764713.1"
                     /locus_tag="EES43_RS20460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_20145"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_124270050.1"
                     /transl_table=11
                     /translation="MTGPLTAVTGASGAVGGRVARRLARVGVPVRLLGRDPARLPDLPG
                     AGHAPPAPYGEPEAMRRALDGAHTLFLVSAHESPDRVREHTTAIDAAVAVGVERIVYVS
                     FQGAAPDATFTFARDHWHTEAHLRTVDVRRTFLRDNWYLAGLPAMTGPDGVLRGPGGDG
                     RVAAVAHADIADAAAAVLLDESTDHDGRVYDLTGPEALTLAEAAEQLSRAAGRTVRYEP
                     ESREAAYASRAGQAEEWEVAGWVTSYEAIARGELAAVSDAVPTLTGHPAQTFAGYLAEN
                     PDSYRHLLPGA"
ORIGIN
        1 cagccgctcg cgcagctggg ccagggtgcg ggccagcagg cgcgagacgt gcatctgcga
       61 gatgccgacc tcctgggcga tctgcgactg ggtcatgttc ccgaagaacc gcagcagcag
      121 gatgcgcttc tcgcgcggcg gcagatcctc caggagcggc ttgagcgact cccggtactc
      181 cacgccctcc agcgcctcgt cctccgagcc cagcgtgtcc gcgaccgccg gggactcgtc
      241 gtccgtgtcc ggcacgtcca gcgacagcgt gctgtacgcg ttggccgact ccagcccctc
      301 cagcacctcc tcctcggaga tgccgagccg ttcggccagc tcgtgcacgg tgggcgagcg
      361 gccgtgctgc tgggacagct ccgcggtggc cgtggtcagc gacagccgca gctcctgaag
      421 gcggcgcggc acccgcaccg cccagccctt gtcccggaag tgccgcttga tctcgcccac
      481 gaccgtaggc gtcgcgtacg tcgagaactc cacgccgcgg tccgggtcga accggtccac
      541 cgacttgatc agcccgatcg tggcgacctg cgtcaggtcg tccagcggct cgccgcggtt
      601 gcggaagcgc cgggccagat gctccaccag cggcagatgc atgcgcacca gccggttgcg
      661 cagctccgcc ttggccgggg agccgtcggg cagctcccgc aactcgatga acagggcgcg
      721 tgccccgctg cggtcctgtg gatcgtggtg cccgtgctcg ctcatctggc ccgcccgctc
      781 tgcctgcgac tgctccaccg cgacgtcgcc ccccggcccg tccgctccgt ccaccggatg
      841 cggccgggcc tgttgctccg ggatgcctgc cggccgcccc accccgggtc ggatcgtctc
      901 gtcccgcaca gcgtccccgt tcccgtcgct cacgccggcc cagggcccgc gccgcgctgt
      961 ttgtagaggc tgatgctgac cgtacggtcg tccgcgaccg tcgaatcgac cttgccggcc
     1021 agtgcggaga gcaccgtcca ggcgaaggtg tcgcgctccg gcgcccggcc gtccgtcgtg
     1081 ggggccgaca ccgtcacctc gagggagtcg tcgacgagcc ggaagacgca gctgaggacg
     1141 gagcccggca cggcctgctg gagcaggatc gcgcaggctt cgtcgaccgc gatgcgaaga
     1201 tcctcgatct cgtcgagagt gaagtccaaa cgcgccgcga gaccggccgt ggccgttcgc
     1261 agcaccgaca ggtaggcacc cgcagcgggc agccggactt ccacgaagtc ctgattcccg
     1321 ggctcgcctg cgatctggga caccctcacc tccaaggtgg cacaaactct ttcgaggttc
     1381 cgggaagggt ggcccggagc catgcggtcg gtcgacggtt ctcagttcgg cgacgctatc
     1441 ggatccatga tgccgtgtcg cccgcccccc atcgcccggc cgtcactcat ggtaagccca
     1501 tgcgtacgga cagtggctag gggtctgcag ggtccaattg cgaagaaccg gcgtcgcctt
     1561 gacgtaccca gacgtcagac gatcgaaccg tcctcgaagc accagcgcca gctctcgccc
     1621 ggttcgaagc tccgcatcac cgggtggccg gtctcgcggt ggtgcccggt agcgtgccgc
     1681 agcggggagg agtcgcagca tccgacgtgc ccgcaggtca ggcagagtcg gagctgcacc
     1741 gggtgcgtcc ccgcggccag gcactccggg caggtctcgc cgagcggcac gggctcgggg
     1801 cgtggcaatt ccgatacgtg tgcacagtcg ctcatgatgg gcaggttacg acggatgcga
     1861 ggacgatgag atggacgcgc tgccgctggt ggggctggtc gcggccagcg ccgccgtcgc
     1921 gggcgcggcg cgccgcaccc cggtgcccgc ccctctcgtg ctggtcgccg ccgggctcgt
     1981 ggccggctat ctgccgggcg tgcccacgta cacgctggac gcgcacgtcg tcctgccgct
     2041 gctcctgccg cccctgctct acacggccgc ggtcgacagc tcctacctgg acctgcgggc
     2101 caacgtccgg ccggtcgccc tgctctccgt gggctacacg ctcttcgcga ccatcgcggt
     2161 gggatggctg gcgtacctga tcatcccgga cctgccgctg accgccgcgc tggtcctggg
     2221 cgcggtcatc gcgccgccgg acgccgtcac ggccgccgcg atcgcccggc gcgtcgggct
     2281 gcccgcccgg gtcaccacga tcctccaggg cgagtccctg gtgaacgacg ccacggccat
     2341 caccgccttc aaggtgctgg tggccgccgc cgtcggcgcg ggcgtgagct ggggcgcggg
     2401 gatcggcgag ttcctgctgg cagccttcgg cggcatcggc gtgggcctgc tgctgatggt
     2461 gccgctgcac tggctgcgca cccatctcca ggaggcgctg ctccagaaca cgctctccct
     2521 cctcatcccc ttcgtggcgt acgcggcggc cgagcgggtg cacgcctccg gggttctcgc
     2581 cgtggtcgtg gtcgccctct acctcgggca ccgctcctgg caggtcgact tcgccacccg
     2641 gctccaggag gcggcggtct ggaagatggt ggccttcgtc ctggagtcgg cggtcttcgc
     2701 gctgatcggg ctccagctgc ccttcgtact caggggcctc ggggcgttcg gggtggcgga
     2761 ggcgctgtgg tacgcggtct tcgtgttcat cgcggtcgtc gtcgtccggt tcgcctgggt
     2821 ctacccggcc accttcctcc cgcgctgggc ctcgcgccgt atccgtgagc gggaaccggg
     2881 caccgactgg acggcgccgc tgatcgtcgg ctgggccggg atgcgcgggg tcgtgtcgct
     2941 ggccgtggcc ttctccatcc cgctggtgcg gcacgacggc gagccgttcc cggcccgcaa
     3001 cctggtgctc ttcctgacct tcaccaccgt gatcggcacg ctggtgatcc aggggctcac
     3061 cctgcccgcg ctcgtccgcg tactgaggct gccgggcagt gacccgaagg ccgagaccct
     3121 ggtcgaggcg caggcgcaga gcgaggcgtc ggcggctgcc gaggaccgcc tggaggaact
     3181 gctcgccgat ccgcacagca acctgccgcc gccgctcgcc gaccggctgc gcggcacgct
     3241 ggagcgccgc cgcaacgcgg tgtgggagcg gctgggcacc tccgatccgg tgaccgggga
     3301 gtcggcggac gacacctacc ggcggctggc ccgcgcgatg atcgccgccg agcgggaggt
     3361 cttcgtccgg ctccgggacg agcggcggat cgacgacgag atgctgcgta cgctgctgcg
     3421 ccggctggac ctggaggagg cggcggccta ccgggagacg gacgactcct gaagcgtgcc
     3481 ggtgatcacg gcggtcaccc ggctgccggg cgggaagccg ccctcctcgg ccagtgccgt
     3541 cagggcgaac aggagcttgg cgacgtagac ccgctccacc ggcagtccgt gccggtcctc
     3601 gaagtccgcg gcgaacgcct ccagctccgg ggtcgtacgg gcgtagccgc cgaaggcgaa
     3661 ccgttcctcc agcgaccagc tcccggccgg gccgccgaag gcctcccgct ggagccgggc
     3721 cacggtctcg ccgaggaagc cgccgcgcag caccgggacg cccagggccc gctgcccggg
     3781 gcccagcccg gcggcgagcc cggccagggt gccgccggtc ccgcaggcga cggccgccac
     3841 ctcggtgagc ccgcgcaact cgcgccccag cgccgcgcag ccccgggcgg ccagggcgtt
     3901 gctgccgccc tccgggacga cctccacgtc cccgaaccgc tccagcagcc ccgccagcac
     3961 ctcgggcgag tccttcgcgc ggtaggacgc ccggtccacg aagtgcagcc gcatgccgtc
     4021 ggcggcgcac cgggcgagcg aggggttgag cggccgacgg gccagctcgt cgccgcgcac
     4081 gacgccgacg gtggggaagc cgagcagccg gccggcggcg gccgtggccc gcaggtggtt
     4141 ggagtaggcg ccgccgaacg tcaggacggt gcgcccggcg gcggcccgga ggttgggggc
     4201 gagcttgcgc cacttgttgc ccggagggta cagctccgct ggtccaagtg cggccgtatc
     4261 ccagtcggga gtgaagtgga tgagatcgtc ccgcttcagc agcagccgaa cgccccggcg
     4321 cgcgaaccgg tcgtcccgca cctcctgcaa gggagaggga ggctggggct gaagtgcacg
     4381 ggcgaggtct acgggcaggc tcaccctccc attgtggccg tgccctctcc ccgcgccgtc
     4441 acggcgtctg cggtacgccc cggtcccaca gctcctcggc atgctccgcg aaccggtcga
     4501 acatgccgct gtcttcctgg cgacgcagat gcagaagcgg tgagtcgtgg ccgacgagcc
     4561 gcgccaggtg tggcgtcacg agtgcgtcat gatcgaacct gaacacggag agggacacat
     4621 ggttcacggc gtcctccggg ctgctgaacc gcgtctccag accgtccagg gggccgagcc
     4681 gtcccagatg ctccaggctg atccggatgc gtgtgccgac actcagggcg acgtcttcga
     4741 tggcctcacg ctgtcgggtc acctctccat cgggatcgcc cagtaggaag cgcacacggc
     4801 accccgacgc gatcttgcgg cgcagcgtct ctatgaaggc aggctgctcc aaccagacga
     4861 agtagttcgt atatccggcg aagaagatgt ccgtggaggc ccctgcgatc agttcacccc
     4921 acacggtcga cgggcaggcg gaccggtagg ggtaggcatg ggccaactcg cggtcatggc
     4981 cggtcttcac ccgttcctga acagccttgg gccagatcat gtcttcatcc accttcagcg
     5041 cccggcacgc gtcgacgcgg tttcttgcat gcggtaacag ctcggcgtcg gccagccacc
     5101 gttccaccgt cttgggtgcc acaccgatac gggtggcaag cttccggggc gtgagcttgg
     5161 cgtcttccat agctgatcgt agagaggcgt tcaagacttc cccctgcgac atttgggcgt
     5221 tcttgaaccg tagtgctcaa cggtacaact gtccctagtt cggggagata tacgtccttc
     5281 aggggcatgg agcatcacgt ccatgacgac tccggacacg accatggacc cgcctgcgca
     5341 tctcatgtcc atcccggagc ctccgaagcc ggtggaggac tgcgacgtgt gccaggcgtt
     5401 ggatgcccag cggcgggagg ccggaggccg gggcgactac tcggcggcta cggacgcgag
     5461 cgtgtgtgac ggcccgccct tgcccgagca ccctgtgaag cgtccggagc gctgctcggg
     5521 aaccctggcg agctggggcc ggagagccgt gagagccttc ggtcccactt ttctgtgctt
     5581 gttcaagggc acgcctgcgg cgcgccgggt ggccggtccg cccggatcgg gcatgcggcc
     5641 tggcggccgg tcccgaccgg gcgaccgcca cccgtccgca gggctcccca gaccgtaagg
     5701 aagccgacgg agcgccatcg gcccctcgcc cttcgttctt cacggcgcgc tgactctcac
     5761 gggccacgtg gctgggggcg gacggcaccg ggaggcttta ggcagccacc agggggcgag
     5821 cctcgaagga ctgggggccg atcgggccat ctgcgggcag gcagggtgcc ggcccgagtc
     5881 gcagcgggag cgtaagaccc ccagtcctct cgcccccttc ccgcccgtag cgatcgtgca
     5941 ccggcatcag ccctaccctc gcggggaagt gcgcgagttg agtgatcgtc gatgaccgcc
     6001 acctgcctcc gcgccgggtg gtgagcccct ccgcgtcgag ttcgtcggcg atcgttccgg
     6061 ctgccttgtc ggccagtagc ccatgtgggc gagcagacgc gcgcccttgg agtcgaactg
     6121 atcaagtacc tgaccgacct gccccggttc ctctttcccg accttgcggg ccgtcaggcc
     6181 ctctcgtacc gcgcgctccc ggagatcacg ttcatgtgtg tgcagagtcg tcttgtcgtc
     6241 ctgcgatgtg ctgcgacgaa gaaacagatc acacagcttg gcaggatctg tgaccgtgcc
     6301 catatggcca ccctcggtcc aggcgggccg ggctgtccac ggaatatgcg cccaggtcag
     6361 cccgacctgc accagtcggc ttgtatctgg ggagttcggg gtggacgaga tcgtcccgct
     6421 tgaggagcag gctcaccccg ctccggtcga agcgctcgtc ccggacgctg tgcagcggcg
     6481 agggcaggac cggccgcagt ccggccgatc cccgcggttc gtggtgcata cgcccattgt
     6541 cgccgcggcg cggatcagcc ggccgccagc cagaggtccg ggccgaacac ctcgtagtgg
     6601 acgtcggcgg ggcgcacgcc ctcggccagc agccgggtac ggacgtcgcg catgaacggc
     6661 agcgggccgc agaggtaggc gtgggtgccc ggcaggacgg tgacggcggc caggtcgacc
     6721 cggccggtgc gctcggccgg gtgtccgggc tccggccgct cgtaccagaa gtgcgccgcg
     6781 gcgtcctcca gctcggcggt cagccgggcg tggtcggcgc gcagggcgtg gtcggacggc
     6841 gaacggtcgc cgtgcacgac gctgaccgga ccccggtgcc cgcgctccgc gaggtgttcc
     6901 agcatggaca gcatcggggt gcagccgatg cccgccgagg ccagcagcag cggggcgtcc
     6961 aggtggtcga gcaccaggtc gccgtagggg gcggagagcc gcagcctgtc gccggggcgg
     7021 acgtgcgtgt gcagccgctg ggacacttcg ccgtcaggcg ttccgtccgc gcggacgtgc
     7081 ttgacggtga tcgagcgcag cggggagccg ggcgatgagg acaggctgta ctggcgtatc
     7141 tggcgggaac cgtcggccag ttccagctgt acggagacgt actggccggg ccggaaggcg
     7201 ggcgcgggcg aaccgtcggc cgggcgcagc cggaacgtgg cgacgtcggg ggtctcctcg
     7261 acgcggccga cgacctccca cgtgcgccac acgtcgcccg ccacgacgcc ccgctgggcg
     7321 tacagcctcg cctccgccgc gatgaggccc cccgccatca gccagtagac ctcgtcccag
     7381 gcggcggcga cctccggcgt gacggcgtcg ccgaggacgt cggcgatggc ggcgaacaga
     7441 tgggtgtgca ccacctcgta ctgggcgggg gtcacgccga gcgacgcgtg cttgttggcg
     7501 atccggttca gcatcacgtc ggggcgggtg tcggggcgct ccaccagttg ggaggcgaac
     7561 gcggcgatgg agccggcgag ggcccggcgc tggtcgccgg aggcctggtt gcctcggttg
     7621 aacaggtcgc gcagcagctc ggggtgggcc gcgaagagct tgcggtagaa gaggtcggcg
     7681 atgtcgccga tggccgcgcc gacggcgggc agggtggcgc gaacggtggc ggtggagcgc
     7741 tcggagagca tggaggggat ctcctcgggg aaaggggccg ctcggggtgc ggcggctcgg
     7801 gatgtggccg ctcggccgtt taattggtat ggaggatgcg tattttcggg cgcggctgtg
     7861 cccgcccggt ggggcggggt ctcagccggt ctccgggccg cggccgatgc cgagcagcag
     7921 cgggccggtg ggggcggtga cgaggtcgtc gaccgtgatc gggtcgagcg tggcgtagaa
     7981 ggcttcctgt gcctgacgca gggcgccgcg cagccggcag gcggagcgca gcgggcaggg
     8041 tgtctcgccc tcgcactcca ccacgtcgcc cgtgccctcc agttcgcgta cgagcgagcc
     8101 gatggaggcg gtgtggccgg cggaggtgag ggtgagcccg ccgccccggc cgcgccgggc
     8161 gtcgagcagc ccgaggtgct ggaggcgcgc gacggtcttg gcggcgtgcg tgtacggcac
     8221 ccgcatggtg gccgccacct cgcgcgtggt cggcggctcc ccgtcctcgg cgaccgccag
     8281 tcgcatgagg acgcggagcg ccacgtcggt gaatctcgtc agccgcatgc gcacatcgta
     8341 gataagtggc atccgcgatg caactttgag ggtccgcctc gcgacgcgca ccaccatgcc
     8401 ccaagagatg gtcgactaat cacactcttt tgtgtaatgg cgcccgcggc cctcgcgctg
     8461 aaaggcttct gcacgcaggt cagcccatga ttgagaggac gtcagatgtc cgttggtgaa
     8521 gaggttcgcg acacgcaggc gccgcagcag agtctgggga cggcggctgc gcggaacctc
     8581 gcgacgacca ccaagtccgc cccgcagatg caggagatct cctcccggtg gctgctgaag
     8641 atgctgccgt gggtgcaggt gcagggcggc acgtaccggg tgaaccgtcg gctcagctac
     8701 tcggtcggtg acggacgggt gaccttcgtc cagaccgggg accgggtgag cgtgatcccg
     8761 ggcgaactgg cggagctgcc cgctctgcgc gacttcggcg acgaggaggt gctcgccgag
     8821 ctctcccgca ggtgcgaaca gcgggacgtg gccgcggggg aggtgctcgc cgcctcgggg
     8881 gacgcggcgg accgggtctt cctgctggcg cacggcaagg tcgagaagat cggctccggg
     8941 ctctacgggg acgagacgga gctcggagtg ctcgccgacg gggcctactt cggcgaccgg
     9001 agcctggtcg acggggacgc cgtctgggag tacaccgccc gcgccgtcac ggcgtgcacg
     9061 ctcctgacgc tcagccgcgc ggacgtgctg aacctcgcgg agcgcgccga gccgctgcgc
     9121 gaccacctcg cgggactgct ctccatcccg caccagagga ccaaccgcta cggcgaggcg
     9181 gagatcgacc tctccgcggg ccacgtcggg gaggcggtcg tcccgcacac gttcgtggac
     9241 tacgacgcct cgccgcgcga gtacgagctc agcgtcgccc agacggtgct caaggtgcac
     9301 agcagggtcg ccgacctcta caaccagccg atgaaccaga ccgagcagca gttgcggctc
     9361 acggtcgagg cgctgcgcga gcgccaggag cacgagctga tcaacaaccg cgagttcggc
     9421 ctcctcaaca actgcgacta cgggcagcgc atccagccgc acgacggcgt gcccggcccg
     9481 gacgacatgg acgaactgct ctcccggcgg cgcggctcga agctcttcct cgcccacccg
     9541 cgggccatcg ccgccttcgg ccgcgagtgc aaccggcgcg gactggtccc ggagagcgtg
     9601 gacgtcggag gccaccacgt gccggcctgg cgcggggtgc cgatcttccc gtccaacaag
     9661 atcccggtca ccggcgcccg caccacgtcg atcatctgca tgaggaccgg cgaggccgaa
     9721 cagggcgtca tcggcctcca gcagaccggc atcccggacg agatcgaacc gagcctgtcg
     9781 gtccgcttca tgggcatcga cgagcaggcg atcatctcct acctcgtgac ggcgtactac
     9841 tccgccgcca tcctggtgcc ggacgccctc ggcgtcctgg agaacgtgga agtcagccgc
     9901 tggcactgat cccgagtcac cccgggcccc gggcggcagc gaccgcccgg gcccccggtc
     9961 ccgcacccaa cgcaccgtcc cccagggagt gaccgtgacc atgaccagta cggacgcagc
    10021 ggcgacggag ggacacgagg ccgccgcgct cctggagcac acccgggccg tcgtcgaccc
    10081 ccctctgcgc gctgccgtgg aatcgctgcc cgcaggcata cgccgggtcg cgatgtacca
    10141 cttcggctgg gagaacgccg acggaacgcc cgcctccggc caggcgggaa aggccatccg
    10201 gccggcgctc gtgctcgccg ccgcccgcgc gctgggcggc gatccggagc aggccgtgcg
    10261 ggccgccgtc gccgtcgagc tcgcccacaa cttcaccctg ctccacgacg acgtcatcga
    10321 cgaggacacc acccgccgcc accgacccac cgcctgggcg gtcttcggca tcccggacgc
    10381 cgtcatcacc ggcgacgccc tgctggccct cgcccagcag cttctcgccg aggatccgca
    10441 cccggccgcc gctcgggccg ccgcccgcct ctcggcctgc gtcatcgagc tgtgcgccgg
    10501 acagcagacc gactgcgcct tcgaggagcg cggccccgac gaggtcaccc tggacgcctg
    10561 cctggccatg gcgaccgcca agaccggggc cctgctcggc tgcgcctgct cgctcggcgc
    10621 gctctacgcc ggggcggagg accgggtggt cggcgcgatg gacggcttcg gccgggaggc
    10681 cgggctctcc ttccagctca tcgacgacct gatcggcatc tggggcgacc cggcgcgcac
    10741 cggcaagccg gtcggcgcgg acctgtccgc ccacaagaag tcgctgcccg tggtcgcggc
    10801 cctcacctcg ggcacccccg ccgccgccga gctcgccgcg ctgtaccggg gagagctgag
    10861 cgcaccggcg gaggtcgccc tggcggccga ctgcgtcgac cgggccggcg gacgggactg
    10921 ggcccaggcc gccgccgccg accggatggc ccgcgcggtc caccacctct cccgggcggt
    10981 ccccgacccg agcgcggcgg acgacctgct ggcactggcc gaattcgtca cccgccgcac
    11041 gtcgtgacgc ccggctcccg gaccgcccgg ccgacccacc ggacggtccg ccggttgtgg
    11101 cccatgtggc ctgttcctta cgcgggttga cgtcccgtcg gagggtggca ccggggctgt
    11161 ccccggtacg ggctacagtc cctgctcatg acagatgagt cgtgggccgg ctggtaccgg
    11221 gacagcaagg gttccgacgc cgtcgtgctc accacggacg gcgtgcacct gcggatccgg
    11281 atcagagggg tcgacttcga gggcgagagt ttcgacgacc tcggacccgt cgccggcata
    11341 ccgcccgaga gcggcatgtt cgccctgtcg ggcggagcgc tgaccgactg cgtcctggag
    11401 tgggaccttc cgctgcccgt gctcgtcgag ggctccctgc gccaggccac cctcagctgc
    11461 ctgctctcgc tgcgccgggt cgacccggac ctctacctcg cgctccatct ggacggcgcg
    11521 gtgtacgaat cggcgcgggc ggaaagcgac ttcgccaccg cgctggccgc cgtccagcgc
    11581 ctcctcccgg acggcgtccg gttgcagacc tgcatcgcct gcgccttctc cgactacttc
    11641 ccggccgccg accgcgggct ctccggcggc ctcgcctgct tccgcggcgc gaaggacgcc
    11701 taccgggaca ccgagggcga ggacgccgtc ctggacctgt gggaccggcg gaccggattc
    11761 gtccaggaga tctggagctg ccgcgagttc gaggcgcggc cggccgaggg ggcgggcacc
    11821 gggcaccggg gggcgttccc gctggaactc gcctgaaccg gtgacctgat gtcctcgtaa
    11881 cctgcctgaa ccgtgacctg atgtcctcgt aacctgcctg aaccgtgacc tggcgtcctc
    11941 gtaacctgcc tgaaccggtg acctggcatc ccggtaaccc gcgccgccgc ccggtcctcc
    12001 cggtgactcc tgaccgcctc ccggtgactc ctgaccggga gggccgggag gactgggagg
    12061 actgggagga ctgggaggac cgggaggacc gggcagcggg ccgtgtttga ccttgacacg
    12121 gtgacaaggt cttcactgct tctcaaggag gtggtcccga tggccatggc gaggcaggac
    12181 acggatgcgg gacgagcgct ccgggcgctg gaggacgggc gttcgtccgt acggcttcgg
    12241 gcggctctgg cggtcgggac ggcgccggac ccgtgcttcg tcggcaagct cgtcgagcga
    12301 tgcgcgatcg agcccgagtt cttcgtccgc gacatgctga cctgggcgct gacccgccac
    12361 ccggtgtccc tcacactccc cgaactgctc cgcgaggtcg gctcggagcg tgcgcgggca
    12421 cgcagtcagg cgctgcacac gctgtccaag atcggggacc ggcaggcatg gccggcgatc
    12481 acccgggcgc tgttgtgcga caccgacgac gaggtggccc ggagcgcctg gcgtgccgcg
    12541 gtcgtgctcg tgccgggagg cgaggagccc tccctggccg cggtgctggc gacgcaactc
    12601 gggcgcggtg ggcgggagac gcagctgagt ctgagccagg cgctggttgc gctgggggac
    12661 gtgatcgtgc cggttctgga caccgcgacg acggtctccg acccgcaggt gcgagcgcac
    12721 gcgctcgcga cacagggact gctgcgcgac ccggacgccg gattcgcgtc ggcggtcgag
    12781 gaggccaggc gcgccgtggc cctcaccggg gctcccggga cggacgatga ggaccgtgct
    12841 gatcggtgag gtgtcgagac ggtccggggt cagcgcccgc atgctccggc actacgaatc
    12901 cctcggcctg gtgcggcctt cggggcgtac gggatccggc tatcgggagt actcggcgga
    12961 ggacatccgg cggatcttcc acatcgagag cctgcggtcc ctgggcctgt cgctgcgtga
    13021 ggtcgggcgc gcgctcgacg atcccggttt cacgccctcg gcgctcgtcg gcgacctcat
    13081 ccgtcggacg ctcgaccgca tcgcggccga gaccgatctg ctgacgcagc tccgccggat
    13141 ccatgccgcg gaccccgtcg gctgggcgga cgtcctccag accgtcgcgc tcctccaagc
    13201 gctggggtcg acgagtgccg acgtgcgtca gcgcgcggtg ctctcctcgg gggacgaggc
    13261 gccggtggag gctctggtcg aggcggcgct cagcgagacg gagccgagcg tcgcgggggc
    13321 cctgcgatgg gcgctcgcac gatcggacga cggcgcgcgg gcgctgctgg ccgaaggtct
    13381 cggctcaccc gtggccgccg tgcgggaacg cgccgttcag gccctcgtcg agctgcccgg
    13441 cgacggagcc gccgcgcagc tgcgggtcgc cctcgcgaac tccgacgcgg tggtccgcgg
    13501 gtatgcggcc gtggcgctcg gtacacgcgg tgaggccgaa gcggtcccgg cgctgctcga
    13561 catgatcgtg gaggggagga acgacaccga cgcggccgat gcgctgagcg tgctggcgag
    13621 tgacaccccg acggcggacc ggatcacgac ccggctcgtc gaccgcctgg ccgacggcgc
    13681 caccgaggcg cccgcacgcg gccggctgac ccaggcactg gcggacattc ccgggacgac
    13741 ggcatcgcgt gccctcgtgg agctgtcgca tgacgaggac cccgccgtag cgctgaccgc
    13801 cgcctacctt cttcaactcc gcgacacccg ttgacgtatc tctcctcggc caccccgcac
    13861 gcggcccccc tcggggcgga ggaagcccgg acctgtcgcc gtccacggaa gggaagccgg
    13921 gaccgtgacg cacgcttccg ccccgccgtc gcgggccgtt gtccgtcgcg atccgttgtc
    13981 acgacctcat tgttctacta acatgcgaac aacggaggtt ttcatgacac gcacgaacct
    14041 tgaccgcgtc actctcgccg ccctgccctt tgtcctcgct ctcctcgtcg acctcgtcct
    14101 cttcgccgtc ctcaaggacc gcctgcccgg ccggatcgcg agccacttcg gcgtcgacgg
    14161 cgcggccgac ggccatgtgg gccgcaccgc ctacgtcctc gccaccacac cggtcctgat
    14221 cgtgctcggc gcgctgtggg gcctggcggc cgtccgcggg aagttccacg ggcgtgctca
    14281 tcgccgtttc ctcggcgcgg gctgggccct cgccggcttc ctcgggtacc tctcggccgc
    14341 cgtcctcacc gtcaacgcgg acgcccccgg cggcgggccc gccgaccgcc ttccgccggg
    14401 ccatctcgcc gccgccgtcg cggtggccgt cctcgccggg gccctggggc tgctggccgc
    14461 ccgcgccgtc cccgcgcccg ccgccccgtc cgcgtacggc gatcgcgccg ggcgcggccg
    14521 gatcgtgctc gccgaggggg aggtggcggg ctgggcgcgg agcaccggcg cctggtggct
    14581 gcccctggcc gcggcggcgc tcctggccgt cggcgtggtg ctcgggctcc ggctgagctg
    14641 gttcgccgga gcgccggtcc ttctcctggc gctgcccgtc ctctgcttct gccgcccgta
    14701 cgtcacggtg gaccggcgcg gcctcacggt ctccggcctg ctgccctggc cccgcgtccg
    14761 ggtgccgctg gaacggatcg cggcggcgga cagcagacgg gtcgacgccc ttgccgagta
    14821 cggcgggtgg ggctaccgcg tccgtcccgg ccgcaccggc ttcatcgtcc gctcgggcga
    14881 ggccatcgtc gcccggcaga ccggcggacg cgacttcgcc gtcaccgtcg aggactcggc
    14941 caccgccgcc gccctgctca acaccctcgt cgaccggcac cgggcaggtc gctgaccatg
    15001 ctcttccgcg tcgatcccac ctccaccgtg ccgctcggcg accaggtcgc ggcctcggtc
    15061 cggcgagccg tggccgacgg cacggtgacc ccgggcgaac ggcttccggc cgcccggatc
    15121 ctcgccgagt ccctcggggt gaacgtccac acggtgctgc gcggctacca gcggctgcgc
    15181 gaggaagggc tcatcgagct gcgccgcggg cgcggcgcgg tcgtcaccgc gggcgcctcc
    15241 ccgcaccggg cccgactgct ggagcgcgtc cgcgaagtgg tcgcggacgc ccgcgacctg
    15301 ggcatgaccg aggaggaact gctcctcctg gtccgcgccg aactgagcgc ctgacgcagg
    15361 cccaggcccg cgaggcgcat gccgacgggc ccgcgtgccc accgctgcgg gcacgtggaa
    15421 caggggccgt tccgtctccg gacactgttg gtaaatgagg gcccctggtt gcgtcccgct
    15481 gccgtcaggc agcgggacgc agtcgttcga accgagagac gcgggttccg gnnnnnnnnn
    15541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngt ctccggaacg
    17041 gcccctgttc ggtgggggcg ccggccggcc ccgggacacg ggaccggccg gcctcagccg
    17101 cgtggtgcgg tgccgcggcc gtgcgcggcg gtgtgcgtgt gcgttcctgg ggccgtcgtc
    17161 gaaccaccgc ccgccggggt gcgggcggga cgccggtccg gtgacggccc cggcggtcag
    17221 cgggtggctt cggccagcgc ggcggcgaag ccgttctgcc agagcgagtc gacctgggcg
    17281 cgctcgttgg cgtccgggtt ggcgttggtg caggacgtgc cggggccgcc gcccgacatc
    17341 agctcgctgc acgggccggc gtagttgtcg ggcaggccga gcacgtggcc cgtctcgtgc
    17401 gtggtgacgc gcgtcgcgtc gtactgctgg ttctgggcgt agtccaggaa gatgaagccg
    17461 ccgcccttgc cgtcggtgct ggcgtaggag ccgcgcgggt cgttgccctc gcggtacgtg
    17521 aagtccgcgt tggagccctc ctgcaacgtg acgttggaga ccgagctgtt ccagatctgc
    17581 gtgctgctgg ctatctggct gctgaaggtc ggcgcctgcg acgcgtcgta gaccacggtg
    17641 acggcctgga cgccgggctt ggccgcctgc ttctcggcga cggacttcag gaccgcgtcg
    17701 aagaaggcgc ggttggcccg ctcgttcgcg gtcgacgagg cggtgtatcc ggcgacgtcc
    17761 gcggcggccg cggggggagc ggcaggggcg ggagcggcgg cgatcgcggg ggcggtgccc
    17821 agggcggcga cgaggccgag accggcgacg gcggaggcga aagcggtccg gaggtgtctc
    17881 atggggggtt ctcctacctg tccgatgtac ccgcaccgtg ggggtgtccg gcgaacggac
    17941 gagtgcgggg gcggtacggg ggagagtctg gaggagcgaa cctgcggcgg ggatgatgtc
    18001 aaaccccgat aacgcggtcc tatcgccgtc acctgcacgt gacggccacg gcatcctcac
    18061 atgtcgggcc gcccaacagt ccctgaattg acgttttttg atggggttgc tgtagctggt
    18121 gcgcgggtgc ggacggtcat agtctccgct gcatggagct cgaggtgagg catctcaggg
    18181 cgctgtgcgc catcgccgac gcgggcagtc tgcaccgggc ggcccgccgt ctcggcgtca
    18241 gccagccctc gctgaccacg caactgcggc ggatcgagaa ctcgctgggc gccgaactct
    18301 tccgccggga acgcaccggc tgccggccca ccccgctggg ccgctccgtc ctgagccggg
    18361 cccgacctct ggtcgacggt atgagcgcgc tggtcaacga cgccctcgca gaggcggagg
    18421 ccgcccgccc gcgcggcccc gggctgcgca tcggctccac cgcgagccgg gtgatcggcg
    18481 gctggctgcg ccggctgcgg gtggcgatgc cgggtacgga catctcgctg cgggtcgacg
    18541 tctccgccca cgccttgctg cgctcggtcg aggcgggccg gctggacgtc gccttcgtcc
    18601 acgaggtgga gggcagcccg ctcgccgtcc ccgagggcct ggaacagcgc gtcctgctcg
    18661 accgcgaacc ccagttcatc tcgctggccc ggacccaccc ggccgcccgg cgccgcgtgg
    18721 tggacctgcg cgacctggcc ggcgacccgt ggatggtgga cccgagcgtg gacggcgagt
    18781 gggacggagt gcggcggatg ctcggcgccg ccggactgaa cccgcccgtc ctgcacggcg
    18841 actacctcac cgccgcctcc ctcgtggcgc tcggcgaggc cgtcgccctc tgccagccca
    18901 cctccgggcc ccgcgacgac acggtcatcc ggccgctgcg cgacgacccg ctcgccgtgc
    18961 gcctcctcct ggtctcccgg cccggggccg acatggccgg ggtctacgcc gaactggagg
    19021 ccgcctaccg ggaggccgcc cggcgttcga gcggctacca cgagtggctg ctgcgccacc
    19081 gcagcccact ggcccacgcc gcctgaccgg cagcccgcct cgcgccgccg cacgcgccga
    19141 ggaccggggc gttagcgtgg cccgatgacc gagccactgc tgcacctcgc cgaagcaccc
    19201 ctgtgggagg cggcccgcgg gaccgggacg tacgagatgt ccacccgcgg tcgcaccctc
    19261 caggaggagg gcttcatcca ctgctcgctg ccccaccaac tccccggcgt cgtgcggatg
    19321 ctgtacgggt cggacgaccg ggacctggtg gtgctggtcg tcgaccccgc ccggctcacc
    19381 gccccggtcc gctacgaggc gatggagccg ggcggggagg agttcccgca cgtgtacgga
    19441 ccgcttccgg tggacgcggt cgtggaggtc cgcccctggc cggcgtccca ggcggcctcc
    19501 gaggagcgac gagaggaagg cggagcccgg tgaccggacc cctcaccgcc gtgaccggag
    19561 cgagcggagc ggtcggcggc cgggtcgccc gccggctggc ccgggtcggc gtgcccgtac
    19621 ggctcctcgg ccgcgacccc gcacgcctgc cggacctgcc cggcgccggc cacgcgccgc
    19681 ccgcgcccta cggcgaaccg gaggccatgc gccgggccct ggacggggcg cacaccctgt
    19741 tcctggtctc cgcgcacgag agcccggacc gggtccgcga gcacaccacg gcgatcgacg
    19801 cggccgtcgc cgtcggcgtc gaacgcatcg tgtacgtctc cttccagggg gccgcgcccg
    19861 acgccacgtt caccttcgcc cgcgaccact ggcacaccga ggcccacctg cgcaccgtcg
    19921 acgtccgccg caccttcctg cgcgacaact ggtacctggc cgggctgccc gcgatgaccg
    19981 gccccgacgg cgtgctgcgc gggcccggcg gcgacggcag ggtggcggcg gtcgcgcacg
    20041 cggacatcgc cgacgccgcc gcggccgtgc tgctcgacga gagcaccgac cacgacggcc
    20101 gggtgtacga cctcaccggc cccgaggccc tgaccctcgc cgaagcggcc gagcagctga
    20161 gccgcgccgc cggacgcacc gtccgctacg aacccgagag cagggaggcg gcctacgcct
    20221 cccgcgccgg acaggccgag gagtgggagg tggccggctg ggtcacctcc tacgaggcca
    20281 tcgcccgggg cgaactggcc gccgtgtcgg acgccgtgcc cacgctcacc gggcacccgg
    20341 cccagacatt cgccggctac ctcgccgaga acccggacag ctaccgccac ctgctgcccg
    20401 gcgcctgagc cgcgcacccg cccgccacac ccggccgcgg gctcaacgcc acggaagatg
    20461 acgccacgga ctgccctcgc tctccgtcag cagacggtgg gcgaggacgt tctgctcgta
    20521 gaacggtccg tactcctcct cgtcgaaccg cagcacccga cccatcgcgt acgccgccga
    20581 gaagtcctcc cacgaccggt gggccgacct gctcagcgcg cccgcgtgga cgatcgcctg
    20641 ctccgcctcg gccggtgtgc cgaaccgcgc cgacaggccc cagcgggcga ggttcaccgc
    20701 gcgtccgtag tcgtacgcca ccgtcgtgcg cacccggccg tccggcggca gcaggccgtc
    20761 cgcgcggaac cgggcctcgt agcgcaggac gcggcgcacc aggtcctcga tgcccctgac
    20821 cgccgcgggg tccgcgccca ggtcctgcgc gtgcccggcg gccgtctccc gccacaggtc
    20881 cgccgacggc agcccgcccg cagccgccgt gagctgttcg cgggcgcgga gtacgaactc
    20941 cggctccggc gggctgttgt cggcgtccag caggaacgcc aactgccgct gccactcctc
    21001 gcgcgtggtg atcccccagg actcccggag cagatcgcgc tcggtga
//
