LOCUS       NZ_ML123034            22720 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4449484
            Orig. end                         :: 4472204
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..22720
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="16"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22720
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22720
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12720](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12720
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    135..149
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    complement(138..151)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.73"
                     /tool="antismash"
     misc_feature    complement(193..206)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.52"
                     /tool="antismash"
     gene            complement(284..739)
                     /locus_tag="EES43_RS19740"
                     /old_locus_tag="EES43_19445"
     CDS             complement(284..739)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EES43_RS19740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EES43_19445"
                     /product="hypothetical protein"
                     /protein_id="WP_124269927.1"
                     /transl_table=11
                     /translation="MRIFKKNTLTSAVGLTTTAVASLVLTAPGTAQAAPVPAAWSVDCD
                     KWTAPNDPGANDMVASIWRSNDSTKAARASFKGSSEKLSISNWSGAMMGYQLQWTTANG
                     STIEKNWELDLGSGKSDEIDFNIPDGRTVYLSVGTPGGSTAYCTGKA"
     misc_feature    complement(720..733)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.06"
                     /tool="antismash"
     misc_feature    731..746
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.44"
                     /tool="antismash"
     misc_feature    911..924
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.93"
                     /tool="antismash"
     misc_feature    complement(1150..1167)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.86"
                     /tool="antismash"
     gene            complement(1289..3418)
                     /locus_tag="EES43_RS19745"
                     /old_locus_tag="EES43_19450"
     CDS             complement(1289..3418)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063248.1"
                     /locus_tag="EES43_RS19745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19450"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_124269928.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.9e-42, bitscore:
                     143.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQKLSFPRQNARTQRFTLGAPRAFTVSPDETRVIFLRSGSGAD
                     RTNRLWVLDPATGEERVAADPEALLGGSAEKLSPQERARRERAREGSSGIVGYAVDAAA
                     ELAAFALSGKVYVAELRAGTARALPVPGPVLDPRPSPDGRHIAYVARGALRVVDAGGGG
                     DRALAEPEDAHVTYGLAEFIAAEEMRRTRGFWWSPESDRLLVARADDRAVRRWWIADPA
                     HPERRPAEVAYPAAGTPNAEVRLFVVDLEGDRTEVVWDRAAFPYLAQVHWSSAGAPLLL
                     VQARDQRSQRYLAVDTATGTTRTVHVDEDPVWLDLFPGVPAWAPDGRLVRIADEGGARV
                     LAVGDRPLTGAQLHVQAVLDIGESDVLVSAVAGEDAAEPETGQVHVYRVNELGIERISE
                     GVGVHSAVRSGGLTVLVSASLDEPGTAAWVVRDGKRLVRVTSTAQEPVLSARVTLTEAG
                     ARRIPCAVLLPAGYREADGPLPVLMDPYGGPHGRRVVAAHNAHLTSQWFADQGFAVVVA
                     DGRGSAGRSPGWEKAVRDNLVLTMEDQVEALRGLAGRFPLDLSRVAIRGWSFGGYLAGL
                     AVLRRPDVFHAAIVGAPVTDQRLYDTHYTERYLGDPAERPEVYAYNSLVTDDGLSQAAD
                     QVRPMMIVHGLADDNVVVAHSLRLSSALLAAGRPHEVLPLSGVTHMTPQEQVAENLLLL
                     QVDFLKRSLGMSGAA"
     misc_feature    3491..3506
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.19"
                     /tool="antismash"
     misc_feature    3494..3507
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(3494..3509)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.78"
                     /tool="antismash"
     gene            3585..3779
                     /locus_tag="EES43_RS19750"
                     /old_locus_tag="EES43_19455"
     CDS             3585..3779
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190440.1"
                     /locus_tag="EES43_RS19750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19455"
                     /product="hypothetical protein"
                     /protein_id="WP_015611142.1"
                     /transl_table=11
                     /translation="MALSISAVVLLAIIVFLLIRKSGLKGGHAVVCMLLGFYIASSSVA
                     PTISDLTSNVAGMIGSIKF"
     gene            3915..4835
                     /gene="mshB"
                     /locus_tag="EES43_RS19755"
                     /old_locus_tag="EES43_19460"
     CDS             3915..4835
                     /EC_number="3.5.1.103"
                     /GO_process="GO:0010125 - mycothiol biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mshB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578614.1"
                     /locus_tag="EES43_RS19755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19460"
                     /product="N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-
                     D-glucopyranoside deacetylase"
                     /protein_id="WP_124269929.1"
                     /sec_met_domain="PIG-L (E-value: 2.3e-26, bitscore: 91.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLPARRLLLVHAHPDDESINNGATMARYAAEGVHVTLVTCTLG
                     EEGEVIPPALASLAADRDDTLGPHRVGELAAAMKELGVADHRFLGGAGRFRDSGMMGAE
                     QNDRPGAFWAAPVDEAAAHLVEVIREVRPQVLVTYDPDGGYGHPDHIQAHRVAMRAADL
                     AADPSYGSGAPHSVAKIYWNRAERSAVEAAFERLRATAPDVFPGVAAVDDVPGVVDAER
                     ITARIDGTAYAGAKSAAMRAHATQIAVDGPFFALSNGLGQPLLTTEYYELARGVAGVPA
                     GDHEDDLFAGLPEAEAAGGPAGAAG"
     misc_feature    complement(3949..3962)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            4832..5299
                     /locus_tag="EES43_RS19760"
                     /old_locus_tag="EES43_19465"
     CDS             4832..5299
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019762338.1"
                     /locus_tag="EES43_RS19760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19465"
                     /product="DUF6113 family protein"
                     /protein_id="WP_124269930.1"
                     /transl_table=11
                     /translation="MSAAARGGGRDRAHAPRTDAPSRAPERTGAAAPLNAARIAGYCGL
                     AVLGVLAAIAGTLVQAAWFPGGLVLALAAAAGLFYGGRILTGTQIGALAPAAGWFVTVF
                     LLLSGRPEGDYVFGDELGLVLFMLGGTGVAVMCATTSRVPQSAIRNSRTVI"
     misc_feature    5302..5312
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            5475..7526
                     /locus_tag="EES43_RS19770"
                     /old_locus_tag="EES43_19475"
     CDS             5475..7526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611145.1"
                     /locus_tag="EES43_RS19770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19475"
                     /product="hypothetical protein"
                     /protein_id="WP_206430089.1"
                     /transl_table=11
                     /translation="MSRETDSSSSGPQGRGGAAYPSGTPPYGSRQYPSLHPSQDGSDET
                     PESVEPPRPEEPRTETTLTTRIRINIPGSRPIPPVVMRTPMGEGDAVPGGRPDAERPGP
                     APRPGTPPPAPPASGAPGAPSAPARDGGPSGEPAAGDRPAKEKSGSDWFAPRKAPPAAP
                     PTAPAATGGAPGAGGGSPAAGGGPGPDGGAGRPRPDLPYFSDAPQSGDGPGAGGSGGGS
                     ALDGYSTAPPAPGPRSTPDLGVRTPGPSGPTTGPVTGSSSLTPNLGGVPGLGGPGPMVP
                     GAPAGGPPGPPRMSDDTAILTPQSPAPEPGHGPVSGDTLTSGIPVVPGEPRSTFPGRPG
                     GPLGGAPGAPVPGSAAAGPAQPAPAPAKKGRSKLVLLGVAAVVLAGVAYGAGLLLNHSE
                     VPKGTTVLGVDIGGGTKEEAVTKLDTALAERAQAPLQLSVGGKRQKLDPEKAGLILDSQ
                     ETVRGAAGSDYNPVSVIGSLFGGARPADPVIPVDEEKLGVALAGLAGASGSANDGTIRF
                     EPNKAVAVPGKPGTSLDVGQSLVSVRDAYRAQVQTGRANVVELPVARTEPTITKAELDR
                     AMKEFAEPAMSGLITIKAGPKQIQFGPARSLPQILSMKPVDGRLVDVYDKKAIETLLDG
                     VFDGITAVKGDGKQHPVGPDDVAQAMKTALTGKTEAERTVTIDLTGQG"
     gene            7759..8262
                     /locus_tag="EES43_RS19775"
                     /old_locus_tag="EES43_19480"
     CDS             7759..8262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446870.1"
                     /locus_tag="EES43_RS19775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19480"
                     /product="DUF4265 domain-containing protein"
                     /protein_id="WP_124269932.1"
                     /transl_table=11
                     /translation="MTPPADPGRAAGDADRIKIWFRCAPREGWSPYASEGLWATRLGAD
                     TARLDNVPFLRDGVAEGETVRFTTDADGVHRAAGRVAESGNCTVRVLPVPDGPLGRDAR
                     AVHERLSPFGLGGEVFSAEFPLVALTVPGGADLRAIKELLERGRDEGWWHFEVSCATEE
                     WRDA"
     gene            complement(8384..8965)
                     /locus_tag="EES43_RS19780"
                     /old_locus_tag="EES43_19485"
     CDS             complement(8384..8965)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611149.1"
                     /locus_tag="EES43_RS19780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19485"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_124269933.1"
                     /sec_met_domain="Mac (E-value: 2.1e-14, bitscore: 51.9,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQKEAMLAGGPYLADDPELAADALRAALLSERFNATSAADPEA
                     RRAALAELLGEVGEGVEIRPPLRVDYGHHISVGPRTFINFGAVLLDVGRITIGADVQFG
                     PNVQLLTPTHPIDPEQRRAKWEGARPITIGDNVWLGGGVIVCPGVTIGEDTVVGAGAVV
                     TRDLPAGVVAVGNPARVIRRIGEEAGEEGS"
     misc_feature    complement(9107..9120)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     misc_feature    9116..9128
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     gene            9188..9547
                     /locus_tag="EES43_RS19785"
                     /old_locus_tag="EES43_19490"
     CDS             9188..9547
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007501416.1"
                     /locus_tag="EES43_RS19785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19490"
                     /product="hypothetical protein"
                     /protein_id="WP_124269934.1"
                     /transl_table=11
                     /translation="MAVARGLAVLTVAAVTLIFGTAGVLVQEHQAEDLHGTGAVVLHVT
                     SGLLAAVTAALSYRRAVGWSLTAAAVLLFGFSFVQSSFGSGDTLNVHVPGAFLVVALSV
                     GLAVVLLRTKVPADR"
     misc_feature    9231..9245
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     misc_feature    9655..9668
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
     misc_feature    9672..9688
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.52"
                     /tool="antismash"
     misc_feature    9943..9957
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.68"
                     /tool="antismash"
     misc_feature    9945..9959
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.3"
                     /tool="antismash"
     misc_feature    complement(9949..9962)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.57"
                     /tool="antismash"
     gene            10001..12720
                     /gene="lanKC"
                     /locus_tag="EES43_RS19790"
                     /old_locus_tag="EES43_19495"
                     /pseudo=""
     CDS             10001..12720
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611152.1"
                     /locus_tag="EES43_RS19790"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19495"
                     /product="class III lanthionine synthetase LanKC"
                     /pseudo=""
                     /sec_met_domain="micKC (E-value: 9.5e-228, bitscore: 756.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.2e-10, bitscore: 39.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-08, bitscore:
                     32.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYAAYCQADRHFYDAPHRSPAGSSPESADADSSFYAPVRGTA
                     PAGWTRSRRGDWLSYSPDGLRLPAQGWKIHISAALDNAESVLRRVADHCLEHRLPFKCV
                     PSPGLLHLRNAKYADRAGSGKFITVYPHSDEAFPEVCAALTALLDGEHGPYILSDLRCG
                     NGPVYTRYGAFAARFCPGPDGRPVPAVADPHGHLVPDERGPSFRIPAWVTPPDMLRPYL
                     EARSAVGLGGLPYTVEKALHFSNGGGVYLARDTRTGEQVVLKEARPYAGLAADGADAVA
                     RLERERTALERLAGLDCVPAVHDVFETGGHHFLVLQHIPGSTLNTVFARRFPLARQRPA
                     PELLAEHAAWADRTYTAVERAVEAVHARGVVISDLHMSNVMVDEDPDRVVLLDFEAASP
                     AADRRRQIVANPAFVAPSDRRGTEIDRYALACLRLALHLPLTTLFGIDRTKAVGLARDV
                     ARIFPVGEEVLRPAVEEILRGADTGASGTSGTLGPAAERTSALPSAPAASPHRPAPAEA
                     PPAPGDWPRSRDSMARAIAASCTPEREDRCFPGDIAQFATVTGGQSFGYGAAGVLYALH
                     ETGAPPCPPAEDWLLRHAKAPASGSPLGFYDGLTGIAWTLHRTGRTAEAADLLRTVLEQ
                     PLEGLPPGLHSGYAGIGLALDDLARDASTADASAADATELAAAAARCTALAARALVQGP
                     PSARTGLMHGASGIALLLVRRYETTGDTALLDLAAAALRRDLERCRPGHDGELLVVEGK
                     RLMPYLASGSVGIAAVIDAYLAHRPDPDLEAAGRALLPAALSAFYIQPGLLRGAAGLLM
                     HLATTPLCDEAERERALRLHSELLGSHAVPYAGELAFPGEQLMRLSMDLATGTAGCLLA
                     LGSAHGTPATLPFLPLRRPAPAAHAAP"
     gene            12759..12890
                     /locus_tag="EES43_RS19795"
                     /old_locus_tag="EES43_19500"
     CDS             12759..12890
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="EES43_RS19795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19500"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_124269936.1"
                     /transl_table=11
                     /translation="MALLDLQAMETPADETFGELATGSQVSLLICEFSSLSVTLCTP"
     CDS_motif       12759..12824
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMETPADETFGELAT"
                     /locus_tag="EES43_RS19795_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12825..12890
                     /prepeptide="core"
                     /locus_tag="EES43_RS19795_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="26.80"
                     /molecular_weight="2058.4"
                     /monoisotopic_mass="2057.1"
                     /core_sequence="GSQVSLLICEFSSLSVTLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMETPADETFGELAT"
                     /leader_location="[12758:12824](+)"
                     /alternative_weights="2076.4"
                     /alternative_weights="2094.4"
                     /alternative_weights="2112.4"
                     /alternative_weights="2130.5"
                     /alternative_weights="2148.5"
     gene            13071..14888
                     /locus_tag="EES43_RS19800"
                     /old_locus_tag="EES43_19505"
     CDS             13071..14888
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611154.1"
                     /locus_tag="EES43_RS19800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19505"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124269937.1"
                     /transl_table=11
                     /translation="MRDRPRPEAASSAGQLARRRPAALLVLLLCTTGGALAALALPAAL
                     GRTVDGLIDGGPVPWSGLLLCAALTLGEAGFDAAAAVVGAGTTARLTAWLRTSAAGRVL
                     AAEPRKVLAVPAGDLTARLTARTADAAAAPVTAVTAAAGVLLPAGAVVGLLLIDPWTAA
                     ALLLGAPLLFVLLRTFTRRTADAGSDYQRAQALIAHRLTEALDGADTIRAARTGAREYR
                     RILEPLGALADHGRRTWSVYGRATGQSALLLPLLMLLVLAIAGVRLAAGAIGVGDLIAA
                     SRYAGLAVGVGPLTGALGALARSRAAARTLEPLLALAPLPHRSLAPPPDGPGRLELRDV
                     GVEHDGRPLLSGVRLTVPGGTSLAVVGRSGSGKSVLAAVAGRLLDPDTGTVLLDGVPLD
                     GMEPARLRREVAYAFERPALPGATVEDTIAFGPWTAPPDAVRTAAREARADDFARRLPY
                     GYATALADAPLSGGERQRLGLARAFAHPGRLLILDDALCALDTLTEHHVQRALDRRDGR
                     TTRIVVTHRLSSAARADRVVWLEDGRVRATGPHHELWADPEYRAVFRTAPPDAPRQREA
                     TAPGAGPTTAAGPTTAALRPAPALGGEPR"
     gene            14885..16687
                     /locus_tag="EES43_RS19805"
                     /old_locus_tag="EES43_19510"
     CDS             14885..16687
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611155.1"
                     /locus_tag="EES43_RS19805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19510"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_124269938.1"
                     /transl_table=11
                     /translation="MTAPEAAERRKGDGALARVMGDARPFLRARAGAVARLSGWSLLEF
                     AQTFLTGYGVARALDDGFLPGRPLTGLLWLGVAAAAVLPAQLATRGVFGRLADLVEPLR
                     DGLVRRAVSRALAAAPHRTDATTASLSQVTHQSEIARDSWAGLVLTLRSFVFTAAGAVA
                     GLLSLAPALLAVVLPPLLLGAALFLATLRPMAARQRDYLTADERYAAHAGRLASCVRDV
                     AAAGAGDRVLAESRDLADTQVRAARSLARWSAVRVLALTVCGRFPPLLLLFAAPWLLRG
                     GLTAGELAGALTYLTQALAPAVQALMTVLATVGGRLVVVLDRFTDAPGPPAEDPPRAAA
                     PARVPDGRAPVAELDRVSFAYGPGAQPVLDRLSLAVGEGEHLAVVGPSGSGKSTLAAVL
                     AGVEPPTEGAVRWRGRPARPCDATALRVLLPQQAYVFTGTLRENLGYLRPDAREREFAA
                     MIDALGLDPLLTRLGSLDAPVEPARLSHGERQLVALGRAYLAGPPLLILDEATSRLDPV
                     AETRAELALAARPGALVVIAHRLSSAQRAGRILVVDGPRTQCGTAAELLDSSELYRDLA
                     GLWTPDGGARTGLDASARTHVAEH"
     gene            complement(16758..17363)
                     /locus_tag="EES43_RS19810"
                     /old_locus_tag="EES43_19515"
     CDS             complement(16758..17363)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127364.1"
                     /locus_tag="EES43_RS19810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19515"
                     /product="response regulator transcription factor"
                     /protein_id="WP_124269939.1"
                     /transl_table=11
                     /translation="MTTVLLVHTVPLWRASLASLLGTGQGIDVRTAEREEIRSALTGKD
                     ADVLLTDLDCPDAMDVLQEIGSLTAPHGRRCSLAVLTEGLRPRGLRRAYEAGARGYIDK
                     YRPADDLCEVMHKLGDGGRHIDESLAFSLLQVADMPLSPRELSVLSLAEGGETVAGIAA
                     RLHLTAGTVRNYLAAAIRKAGGRNRLDAIRLAKEAGWI"
     misc_feature    complement(16962..16964)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17583..18464)
                     /locus_tag="EES43_RS19815"
                     /old_locus_tag="EES43_19520"
     CDS             complement(17583..18464)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956285.1"
                     /locus_tag="EES43_RS19815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19520"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_124269940.1"
                     /transl_table=11
                     /translation="MSAQDSGRAERRRQFTEEARSERPDLALLCLLLGAEAGPVDPSEP
                     RPVTPGEVAPDPYGIDAAQIELDRLAGLVPYGSRSAADWASSLAELLGGRCGFAGSSAD
                     YQRLDSSLLQQVLRRRRGLPILLSVVWIEVARRAGAPVYGVALPGHFVVGFGDPARPVL
                     ADPFAGGVPLTGGDAESLVTAATGAPMDPSLLVPARPLEVVLRILNNVRAWAAARPERT
                     DVALWALDLSLLLPAHPARLRYERAQLLVQRGEFLHGAAEMEEYADVLDGIEPTMAATI
                     RHKARAARSLLN"
     gene            complement(18561..19574)
                     /locus_tag="EES43_RS19820"
                     /old_locus_tag="EES43_19525"
     CDS             complement(18561..19574)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061638.1"
                     /locus_tag="EES43_RS19820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19525"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_124269941.1"
                     /transl_table=11
                     /translation="MEFTIGGRLEVRVTPADVGKRVSVRRRSAGGGAGAGFTDTVGVLT
                     SWDDGVLSITRRNGESVTIAESSLVAGKAVPAAPARRRGPAASFPELAAVTARAWPPVE
                     SEPLGDWRLRASGGFTRRANSALALGDPGLPAAEAFARVRAFYERRGLPPYVQAATGAE
                     GTQEVLCAELERHGWRREVSAEVRIAALAPVGDLDADVSPVRLTRTPDAAWLARYQRLG
                     TPGPHVLRVLGGGPSVWFAAVPGEAADGASGTAPAAIGRMVVDGRWAGFMAVEVAPEHR
                     RRGLATAVMAALARRALEEGASAAWLQVEEDNEGARALYDGMGFAAHHRYHHFRAG"
     gene            19692..20012
                     /gene="fdxA"
                     /locus_tag="EES43_RS19825"
                     /old_locus_tag="EES43_19530"
     CDS             19692..20012
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004950253.1"
                     /locus_tag="EES43_RS19825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19530"
                     /product="ferredoxin"
                     /protein_id="WP_007446848.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDKACIEECPVDCIYEGQRSLYIHPDECVDCGA
                     CEPVCPVEAIFYEDDTPEEWKDYYKANVEFFDDLGSPGGASKLGLIERDHAFIAGLPPQ
                     NQ"
     gene            20158..21252
                     /gene="dapC"
                     /locus_tag="EES43_RS19830"
                     /old_locus_tag="EES43_19535"
     CDS             20158..21252
                     /EC_number="2.6.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-363). E-value:
                     3.5e-45. Score: 146.6. Matches aSDomain:
                     nrpspksdomains_EES43_RS19830_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="dapC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510159.1"
                     /locus_tag="EES43_RS19830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19535"
                     /product="succinyldiaminopimelate transaminase"
                     /protein_id="WP_124269942.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.3e-43, bitscore:
                     146.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAVSSRLPVFPWDRLAPYKKTAQAHPDGIVDLSVGTPVDPVPAV
                     VQQALTAAADSPGYPTVWGTEALRDAITGWLEGRLGAVGVTHENVLPVVGSKELVAWLP
                     TQLGLGPGDQVAYPRLAYPTYEVGARLCGAEPVVYDDPTELDPARLRLLWLNSPSNPTG
                     RVLAKDELTRIVAWAREHGVLVFSDECYLELGWDAEPVSVLHPDVCGDGHQGVVAVHSL
                     SKRSNLAGYRAAFIAGDADVLGELLAIRKHGGMMTPAPVQAAAVAALGDDVHVAEQRAR
                     YADRRLALRSALEAHGFRIEHSEASLYLWATRDEPCWRTVEHLAGLGILVAPGDFYGPA
                     GERFVRVAFTATDERVAAAVKRLS"
     aSDomain        20245..21246
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS19830_Aminotran_1_2.1"
                     /evalue="3.50E-45"
                     /label="EES43_RS19830_Aminotran_1_2.1"
                     /locus_tag="EES43_RS19830"
                     /protein_end="363"
                     /protein_start="29"
                     /score="146.6"
                     /tool="antismash"
                     /translation="IVDLSVGTPVDPVPAVVQQALTAAADSPGYPTVWGTEALRDAITG
                     WLEGRLGAVGVTHENVLPVVGSKELVAWLPTQLGLGPGDQVAYPRLAYPTYEVGARLCG
                     AEPVVYDDPTELDPARLRLLWLNSPSNPTGRVLAKDELTRIVAWAREHGVLVFSDECYL
                     ELGWDAEPVSVLHPDVCGDGHQGVVAVHSLSKRSNLAGYRAAFIAGDADVLGELLAIRK
                     HGGMMTPAPVQAAAVAALGDDVHVAEQRARYADRRLALRSALEAHGFRIEHSEASLYLW
                     ATRDEPCWRTVEHLAGLGILVAPGDFYGPAGERFVRVAFTATDERVAAAVKRL"
     gene            complement(21334..21786)
                     /locus_tag="EES43_RS19835"
                     /old_locus_tag="EES43_19540"
     CDS             complement(21334..21786)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510158.1"
                     /locus_tag="EES43_RS19835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_19540"
                     /product="ATP-binding protein"
                     /protein_id="WP_124269943.1"
                     /transl_table=11
                     /translation="MSLPLTRRIARTALLIAAGAAPVVGAAGAAGAAELPQTSDLGGLT
                     ALDGAGLGNTVDSVAQQSTKAAGDTGGRLVGTALPAAGKAVGRTAAVAAPAAQETVGKT
                     AGQAGELVGEAAGAATEGGVVPAKGLGGLPTGGLVGGLPLNGLPIG"
     misc_feature    22620..22633
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
ORIGIN
        1 gccccctgtc caccccggag gacggtcccc ccgggccgcc ctccgcgggc cgggacgacc
       61 cctcgaaccc gtgactcggt ccacggttcc ttcaactggc cgcgatgaag ggggtgtgcg
      121 gcgagagcgg aatctccttc atgtgagaaa ttccttctgt ggaaatcctt ctgtccggcc
      181 gaaaggaact cttgaagaga gttatcgtgt cgacggggaa ggggctttca taatgtggct
      241 atgcattcga tctcgcaccg atcgaagcgg tgaggcctgg aactcaggcc ttgcccgtgc
      301 agtaggccgt gcttccgccg ggggtcccga cggacaagta aaccgtacgg ccgtcgggga
      361 tattgaagtc gatctcatcc gacttgccgg agccgaggtc gagctcccag ttcttctcga
      421 tcgtcgaccc gttcgccgtt gtccactgaa gctggtaacc catcatggcg ccggaccagt
      481 tgctgatgga cagtttctcg ctgctgccct tgaaggaagc gcgagcggcc ttggtcgagt
      541 cgttcgacct ccagatggag gcgaccatgt cgttggcgcc aggatcgttg ggggcggtcc
      601 acttgtcgca gtcgacgctc caggcagccg ggacgggcgc ggcctgcgcc gtccccggtg
      661 ccgtgaggac gagcgatgcg acggccgtgg tcgtcagacc gacagcgctc gtgagggtgt
      721 tcttcttgaa gatgcgcata tttctcctcg cgacctctcg caaatggtgc aaaggcagca
      781 ggagttcggc cggtcaatcc cctgctcggg cggtccggaa ctcctgcacg ccgagggctt
      841 tggccccggt gcgtcgccga gtattccagg atctgcgaat gtggatcaac gggtttcttg
      901 agcggggctt gaaacggtcg ttccgcgtct gatggttcgc cgttgaattt cagccgtcga
      961 gagatcggga caatttttgg ccggccgaca ggttcggtga gggcggcaac gcgatggcag
     1021 ccgcccgcga aatcgcgtct ccggggcggg tcggcgatag acacagccgc cggaggagcc
     1081 gcgccggaaa ccgaggagcg gtcgctcggg gagcacgatg actcggcagg accgcggcgg
     1141 tcggcgaggt taacaagcag gcaactccac cgacgccgca ccgatatacg gacgccccat
     1201 gatgaacacc gtacggccgt gcgggtgccg tgggccggtc ggggcgtcgt cttgtcgccc
     1261 cggccggtca cccgggcgcc ggcggggctc aggccgcccc ggacatcccc agcgaccgct
     1321 tgaggaagtc cacctggagc aggagcaggt tctccgcgac ctgctcctgc ggcgtcatgt
     1381 gcgtcacgcc gctcagcggc agcacctcgt gcggacgccc ggccgccagc agcgccgagg
     1441 acagccgcag cgagtgcgcg acgaccacgt tgtcgtccgc cagtccgtgg acgatcatca
     1501 tcggccggac ctggtccgcc gcctgcgaca gcccgtcgtc ggtcaccagc gagttgtacg
     1561 cgtacacctc gggccgctcg gccgggtcgc cgagatagcg ctccgtgtag tgggtgtcgt
     1621 acagccgctg gtcggtgacc ggcgcgccga cgatcgccgc gtggaagacg tccggccgcc
     1681 gcagcaccgc cagcccggcc agatagccgc cgaaggacca gccgcggatc gccacccgcg
     1741 acagatccag cgggaagcgc ccggcgagcc cacgcaacgc ctccacctgg tcctccatgg
     1801 tgaggaccag gttgtcccgg acggccttct cccagcccgg cgagcggccc gccgaacccc
     1861 gcccgtccgc gacgaccacc gcgaacccct ggtccgcgaa ccactgcgac gtcagatggg
     1921 cgttgtgcgc ggccaccacc cggcggccgt gcggaccgcc gtacgggtcc atcagcaccg
     1981 gaagcggacc gtcggcctcc cggtacccgg cggggagcag cacggcgcac ggaatccgcc
     2041 gtgcgcctgc ctcggtgagg gtgacccggg cggagagcac cggttcctgg gccgtgctcg
     2101 tgacgcggac cagtcgtttg ccgtcccgca ccacccacgc cgccgtgccg ggctcgtcca
     2161 gggaggccga caccagcacc gtcagaccgc cggagcggac cgccgaatgc acacccaccc
     2221 cttcggaaat ccgctcgatt cccagctcgt tcacccggta cacatggacc tgcccggtct
     2281 ccggctcggc cgcgtcctcg ccggcgacgg cggagaccag gacgtcggac tcgccgatgt
     2341 ccagcaccgc ctggacgtgc aactgcgccc cggtcagcgg ccggtcgccg accgccagca
     2401 cccgtgcgcc gccctcgtcc gcgatccgca ccagccggcc gtccggcgcc caggcgggca
     2461 ccccggggaa aagatccagc cacaccgggt cctcgtcgac atggacggtc cgggtcgtcc
     2521 cggtcgccgt gtcgaccgcc aggtaccgct ggctgcgctg gtcgcgggcc tgcaccagga
     2581 gcagcggcgc acccgccgac gaccagtgca cctgcgccag gtacgggaac gcggcccggt
     2641 cccagaccac ctccgtgcgg tcgccctcca ggtccacgac gaagagccgc acctccgcgt
     2701 tgggcgtccc ggcggccggg tacgccacct cggccggccg acgctccggg tgcgccggat
     2761 ccgcgatcca ccagcgccgc acggcacggt cgtcggcccg cgcgaccagc agccggtccg
     2821 actccggcga ccaccagaag ccccgggtgc ggcgcatctc ctcggccgcg atgaactccg
     2881 ccaggccgta ggtgacatgc gcgtcctccg gctcggcgag cgcccggtcc ccgccgcccc
     2941 ccgcgtccac gacccgcagc gcgcccctgg cgacgtacgc gatgtgccgg ccgtcggggg
     3001 aggggcgggg atcgagcacc ggccccggca ccggaagcgc ccgcgccgtg ccggcccgca
     3061 gttcggccac gtacaccttt ccggacagcg cgaacgcggc caactcggcg gcggcgtcca
     3121 ccgcgtagcc gacgatgccg gacgagccct cccgggcccg ctcgcgccgg gcgcgctcct
     3181 gcggggagag cttttcggcc gaaccgccca gcagggcttc cggatcggcg gcgacccgct
     3241 cctcgccggt cgccggatcc agcacccaga gccggttggt ccggtcggcg cccgaaccgg
     3301 accgcaggaa gatcacccgc gtctcatccg gtgagacggt gaaggcccgc ggtgcgccga
     3361 gagtgaaccg ctgcgtccgt gcgttctgac ggggaaaaga cagcttctgc gaggtcatgg
     3421 ctctgaacct agccccgcgg cgcggtctgt gcgccccctt gtgctgccgt gctccgaaca
     3481 atgcgttggc acggatagtt atgatccgta gcgctcggtg ggtaagaacc tgctggctcc
     3541 gcatgtgctg accgtcccga ccgtactgat ggaggtgaac cgccgtggcg ctttcgattt
     3601 cggcggtggt gctgctggcg atcatcgtct tcctgctgat ccggaaatcc ggactcaagg
     3661 gcggacacgc ggtggtctgc atgctgctgg ggttctacat cgccagctcg tccgtggccc
     3721 cgaccatctc ggacctcacg tccaacgtgg ccgggatgat cgggagcatc aagttctgac
     3781 cgcgcgtcga cggcgccttg accgcgcccc tgacggtgcc ccgaccgcgt tctgaccacg
     3841 tcccgaccga gtcctgaccg ctccgcccgc cgccgacgac cgggcgcgtc cgcgggactc
     3901 gtagggtggt ccccatgaag gaccttcccg cccgccgtct gctgctggtg cacgcgcatc
     3961 cggacgacga gtcgatcaac aacggcgcca ccatggccag gtacgcggcc gagggcgtcc
     4021 acgtcacgct ggtcacgtgc acgctgggcg aggagggcga ggtcatcccg cccgccctcg
     4081 cctccctcgc cgccgaccgg gacgacacgc tcggccccca ccgcgtcggc gagctggccg
     4141 ccgcgatgaa ggagctgggg gtcgccgacc accgcttcct cggcggcgcg ggccgcttcc
     4201 gggactccgg gatgatgggc gccgagcaga acgaccggcc cggcgcgttc tgggccgcgc
     4261 cggtcgacga ggccgccgcc cacctcgtcg aggtgatccg cgaggtccgc ccgcaggtcc
     4321 tggtcaccta cgaccccgac ggcggctacg gccaccccga ccacatccag gcccaccgcg
     4381 tcgcgatgcg cgccgccgac ctggccgccg acccgtcgta cggctccggc gcgccgcact
     4441 ccgtggcgaa gatctactgg aaccgggcgg agcgctccgc ggtcgaggcc gccttcgagc
     4501 ggctgcgcgc caccgcgccg gacgttttcc ccggcgtcgc cgccgtggac gacgtgccgg
     4561 gcgtggtcga cgccgagcgg atcaccgccc ggatcgacgg aacggcgtac gccggggcca
     4621 agtccgcggc gatgcgcgcc cacgcgaccc agatcgcggt ggacggcccc ttcttcgccc
     4681 tctccaacgg cctcggccag ccactgctga ccaccgagta ctacgagctg gcgcggggcg
     4741 tcgcgggcgt acccgccggc gaccacgagg acgacctgtt cgcgggcctg cccgaggccg
     4801 aggcggcggg cggcccggcg ggagcggccg gatgagcgcc gcagcccgcg gcgggggccg
     4861 cgaccgcgcc cacgcgcccc gtaccgacgc gccctcgcgc gctcccgaac gcaccggagc
     4921 cgccgccccg ctcaacgcgg cccggatcgc cggatactgc ggcctcgccg tcctcggcgt
     4981 gctcgcggcg atcgccggaa cgctcgtcca agcggcctgg ttcccgggcg gattggtcct
     5041 cgccctggcc gccgccgcgg gactcttcta cggtggccgt atcctgaccg gcacccagat
     5101 cggggcgctc gccccggccg ccggctggtt cgtcaccgtc ttcctgctgc tgagcggacg
     5161 gccggaaggc gactacgtgt tcggcgacga actcggcctg gtgctcttca tgctcggcgg
     5221 aaccggcgtc gctgtgatgt gcgccaccac gtccagagtg ccgcaatcag ccatccgcaa
     5281 cagccggacc gtcatctgaa gtgccatgtc ccagcccgcg accgcccccg cgcacatgac
     5341 gcgaggggag cggtttcccc cggtcgcggc gtgcccggcg gccacggcca gtatggtggt
     5401 gcgcgcgccg agccgtcccc tggcctgcgg catgggggaa gtacgggcgg cggagccaat
     5461 cgggagaacc tgctttgagt cgtgaaactg acagttcgtc ctccgggccc caggggcgcg
     5521 gtggagccgc gtacccgtcg ggtacgccgc cgtacggatc acgccagtat ccgtcgctgc
     5581 acccgtcgca ggacggctcg gacgagaccc cggaatccgt ggaaccgccc cggcccgagg
     5641 aacccaggac cgagacgacg ctgacgacgc gcatccggat caacatcccc gggtcgcgcc
     5701 ccatcccacc ggtcgtgatg cgcacgccga tgggcgaggg cgacgccgta ccgggcggcc
     5761 gtcccgacgc cgagcgcccc ggtccggcgc cgcgccccgg cacgccgccc ccggcgcccc
     5821 cggcgagcgg cgcgcccggc gcgccgtccg ctccggcgcg ggacggcggc ccgtccggcg
     5881 aaccggcggc cggcgaccgc ccggccaagg agaagagcgg cagcgactgg ttcgcaccgc
     5941 gcaaggcccc gcccgccgcc ccgccgaccg ctccggcggc caccggcggc gcgccgggcg
     6001 cgggcggcgg ctccccggcg gcgggcggcg gccccggccc ggacggcggc gcgggcaggc
     6061 ctcgtcccga cctgccgtac ttctcggacg ccccgcagtc cggcgacggt ccgggcgcgg
     6121 gcggttccgg cggcggcagc gcgctggacg gctacagcac cgcgcccccg gcccccggcc
     6181 cccggtccac gccggacctc ggcgtccgta cgcccggacc ctccggcccc accacgggcc
     6241 cggtcacggg cagttcgtcg ctgaccccga acctgggcgg cgtcccgggg ctcggcggtc
     6301 ccggtccgat ggtcccgggc gcgcccgccg gcggaccgcc cggaccgccc cggatgtcgg
     6361 acgacaccgc gatcctgacg ccgcagtccc cggcgcccga gcccggccac gggcccgtct
     6421 cgggcgacac gctgaccagc ggcatcccgg tcgtgcccgg ggaaccgcgc tcgacgttcc
     6481 cgggccgtcc gggcggcccg ctgggcggtg ctcccggcgc gcccgtgccc ggatccgccg
     6541 ccgcgggtcc ggcgcagccg gctccggccc cggcgaagaa gggccgctcc aagctggtcc
     6601 tcctcggcgt ggccgccgtc gtgctggccg gtgtcgccta cggcgcgggc ctcctgctga
     6661 accactccga ggtgcccaag ggcaccaccg tgctcggcgt cgacatcggc ggcggcacga
     6721 aggaggaggc ggtcaccaag ctcgacaccg cactcgccga gcgcgctcag gcccccctcc
     6781 agctctcggt gggcggcaag cggcagaagc tggacccgga gaaggccggt ctcatcctgg
     6841 acagccagga gaccgtgcgg ggcgcggcgg gcagcgacta caacccggtc tcggtgatcg
     6901 gttcgctctt cggcggggcg cgccccgcgg acccggtcat cccggtcgac gaggagaagc
     6961 tgggcgtcgc gctggccggt ctggcgggcg cttccggctc cgccaacgac ggcacgatcc
     7021 ggttcgagcc gaacaaggcc gtggcggtgc cggggaagcc cggcacttcg ctggacgtcg
     7081 gccagtcgct ggtctccgtc cgcgacgcct accgcgccca ggtccagacg ggccgggcca
     7141 acgtcgtcga actccccgtc gccaggacgg aacccaccat caccaaggcc gaactggacc
     7201 gggcgatgaa ggagttcgcc gagcccgcga tgtccggtct gatcaccatc aaggcggggc
     7261 cgaagcagat ccagttcggt ccggcgaggt ccctgccgca gatcctgtcg atgaagccgg
     7321 tcgacggccg actggtcgac gtctacgaca agaaggccat cgagaccctt ctggacggcg
     7381 tcttcgacgg catcacggcg gtcaagggag acggaaagca gcacccggtg ggcccggacg
     7441 acgtggcgca ggccatgaag accgcgctga ccgggaagac cgaggccgag cggacggtca
     7501 ccatcgacct gaccggccag ggctgacccc gcgcaccgcg ccgcagcacc cccgcccgac
     7561 gcgccaccgc ctgcccgccg cccccgtccg gaacctccgg gcgggggcgg cggcgcgaac
     7621 gcccgcgctc ctcggaggga gcgcgccggt cctgcgcggc tgagcgaccc cgtacggggg
     7681 cctgcgcgcc cgcgacgcac cggaagccgc ccgcctcccg gacgggcggc tgcggtgcgc
     7741 aggggggacc atggggccat gaccccgccc gccgatcccg gccgcgcggc cggcgacgcc
     7801 gaccggatca agatctggtt ccgctgcgcg ccgcgcgagg gctggtcgcc gtacgcgagc
     7861 gaggggttgt gggcgacgcg gctgggcgcg gacaccgcgc gcctggacaa cgtgcccttc
     7921 ctccgggacg gggtcgccga gggcgagacc gtacggttca cgaccgacgc ggacggggtc
     7981 caccgggcgg ccggacgcgt ggcggagtcg ggcaactgca ccgtgcgggt gctgcccgtg
     8041 ccggacggcc cgctcgggcg cgacgcccgc gccgtgcacg agcggctgtc gccgttcggg
     8101 ctgggcggcg aggtcttcag cgcggagttt ccgctggtgg cgctcaccgt gccgggcggc
     8161 gcggacctcc gggcgatcaa ggagctgctg gagcgcggcc gggacgaggg ctggtggcac
     8221 ttcgaggtct cgtgcgccac cgaggagtgg cgggacgcct gaccggccca cgggcccgcc
     8281 gcgcacgggc ctgccgcgca ccgcccgccg cgcacgggcc tgccgcgcac cgcccgccgc
     8341 gcacgggccc gccgcgcccg gccgccggac ggcccggccg ccctcaggac ccctcctcgc
     8401 cggcctcctc gccgatccgc cggatcaccc gggccggatt gcccaccgcg acgactccgg
     8461 ccggcaggtc cctggtcacc accgcccccg ccccgaccac cgtgtcctcg ccgatggtca
     8521 cccccgggca gacgatcacc ccgccgccca gccacacgtt gtcgccgatc gtgatcggcc
     8581 gagcgccctc ccacttggcg cggcgctgct cggggtcgat ggggtgggtc ggggtgagca
     8641 gttggacgtt cgggccgaac tgcacgtcgg ccccgatggt gatccggccg acgtccagga
     8701 gcaccgcgcc gaagttgatg aacgtacgcg ggcccacgga gatgtggtgc ccgtagtcga
     8761 cccgcagcgg cggccggatc tcgacgccct cgcccacctc gccgaggagt tccgccaggg
     8821 cggcgcggcg ggcctcgggg tcggcggcgg aggtggcgtt gaagcgctcg ctcagcaggg
     8881 cggcccgcag tgcgtcggcc gccagttccg ggtcgtcggc gaggtagggt ccgccggcga
     8941 gcatggcttc cttctggctg gtcatgaggt cgtcttccct cggtccgggt gatgggttac
     9001 gggacagcgc tcaggtgatg gattacggga cagcgctcag cagtgtgccc cggaccgcgg
     9061 aacgaccctg ggccctgccg gtcgggcttt tcccttccag gccgtgtgaa tgggcttgcg
     9121 atcggcaata ctgtgttcca tgactaccac cgaaagaaaa gctcactttc ccccggtgag
     9181 tcggctgatg gcagtcgcca gaggactcgc cgtcctgacc gtcgccgccg ttactctcat
     9241 tttcgggacg gccggtgttc ttgtgcagga acaccaggcc gaggatcttc acggaacagg
     9301 ggccgtcgtc cttcacgtca cgtccggtct gctcgcggcg gtcacggcgg cgttgtcgta
     9361 ccgcagggcg gtgggctggt cgctgaccgc ggcggcggtg ctgcttttcg gattctcgtt
     9421 cgtccagtcc tccttcggca gcggtgacac gttgaacgtg catgtgccgg gggctttcct
     9481 ggtggtcgcc ctctcggtcg ggctggccgt cgtgctgctg cggaccaagg tcccggcgga
     9541 cagatagccc ttccggccgg tcgctccggc cgccgtcgaa ttccgttgcg gccatgaatt
     9601 ccctggcgcc tatccctccc gcgtaattac gggacgcctc tcggccccgg ccggcaaacg
     9661 ctcattcggt gtgcgcattt cgggcgcgcc tttcgcgcgg tgccattctc ggtggctttt
     9721 cggcggacag ccggcggccg gggatcggga tcgtcccggc cgccgctccg acgcgccgac
     9781 cgctccgacg cgcccgcctc ccctcgcgcc gccttcctcg gcccgacggt ccggcgcagc
     9841 cgccgcgcac gcttccgcag cggtcaccgc accgcgccgc gatgcggtcc gcatgcatcg
     9901 cgcgcatgta tgagtcgtga caacggtgac tattggcggc cgtcctcgtt gtgacaattt
     9961 ttccctcgcc acgaaggaag cctgagcgag gggaacgtgc gtgaatccgg agtacgccgc
    10021 gtactgccag gcggaccgcc acttctacga cgcaccgcac cgctcgcccg ccggttcctc
    10081 gcccgaaagc gccgacgcgg acagctcgtt ctacgccccc gtccgcggca cggcccccgc
    10141 ggggtggacc cgctcgcggc gcggcgactg gctctcctac agccccgacg ggctccggct
    10201 cccggcccag ggctggaaga tccacatatc ggccgccctg gacaacgccg aatccgttct
    10261 gcgccgggtc gccgaccact gcctggagca ccggctgccc ttcaagtgcg tgccgtcgcc
    10321 cggcttgttg cacctgcgca acgccaagta cgccgaccgg gccggcagcg gtaagttcat
    10381 cacggtctac ccgcactccg acgaggcgtt ccccgaggtg tgcgccgcgc tcaccgccct
    10441 gctggacggc gagcacggcc cgtacatcct gagcgatctg cggtgcggga acggacccgt
    10501 ctacacccgg tacggggcgt tcgccgcccg cttctgcccc ggtccggacg gccggcccgt
    10561 gcccgccgtc gccgacccgc acggccatct cgtgcccgac gagcggggcc cgtccttccg
    10621 gatacccgcc tgggtgacac cgcccgacat gctgcgcccg tatctcgaag cgcgctccgc
    10681 cgtcggcctc ggcggcctgc cctacaccgt cgagaaggcg ctccacttct ccaatggagg
    10741 cggcgtctac ctcgcccgcg acacccgtac cggcgaacag gtcgtcctca aggaggcccg
    10801 cccgtacgcc ggactggccg ccgacggagc cgacgccgtc gcccggctgg agcgcgagcg
    10861 caccgcgctg gagcgcctgg ccggtctgga ctgcgtcccg gccgtgcacg acgtcttcga
    10921 gaccggcggc caccacttcc tggtgctcca gcacatcccg ggctccacgc tcaacaccgt
    10981 cttcgcccgc cgcttcccgc tcgcccggca gcggcccgcg cccgaactgc tcgccgaaca
    11041 cgccgcctgg gccgaccgga cgtacacggc ggtcgagcgc gccgtcgagg ccgtgcacgc
    11101 ccggggcgtc gtcatcagcg acctgcacat gagcaacgtc atggtggacg aggacccgga
    11161 ccgcgtcgtc ctgctcgact tcgaggccgc ctccccggcg gccgaccggc gccgccagat
    11221 cgtcgccaac ccggccttcg tcgccccgtc cgaccggcgc ggcaccgaga tcgaccgcta
    11281 cgccctcgcc tgcctgcggc tcgccctcca cctcccgctc accaccctct tcggcatcga
    11341 ccgcaccaag gccgtgggcc tggcccggga cgtggcgcga atcttcccgg tcggcgagga
    11401 ggtcctgcgg cccgccgtgg aggagatcct gcgcggcgcg gacaccggcg cgtccggcac
    11461 gtccggcacg ctggggcccg ccgccgaacg cacctcggcg ctcccctccg cgcccgccgc
    11521 ctccccgcac cggcccgccc cggccgaggc cccgcccgcg cccggcgact ggccgcgcag
    11581 ccgcgactcg atggcccgcg ccatcgccgc ctcctgtacg ccggagcgcg aggaccggtg
    11641 cttccccggc gacatcgcgc agttcgccac ggtgaccggc ggccagtcct tcggctacgg
    11701 cgcggccggc gtgctctacg ccctgcacga gaccggcgcc ccgccgtgcc cgcccgccga
    11761 ggactggctg ctgcggcacg ccaaggcccc ggcctccggc agcccgctcg gcttctacga
    11821 cggcctcacc ggcatcgcct ggaccctgca ccggaccggc cgcaccgccg aggccgccga
    11881 cctcctgcgc accgtcctcg aacagcccct ggaggggctg ccgcccggcc tgcacagcgg
    11941 atacgccggt atcggcctgg ccctcgacga cctggcccgc gacgcctcca ccgccgacgc
    12001 ctccgccgcc gacgccaccg agctggcggc agccgccgcc cgctgcaccg ccctcgccgc
    12061 ccgcgccctc gtccagggcc cgccgtccgc gcgcaccggc ctgatgcacg gggcgagcgg
    12121 gatcgccctg ctcctcgtcc gccgctacga gaccaccggc gacaccgccc tgctcgacct
    12181 ggcggcagcc gcgctgcgcc gcgatctgga gcggtgccgc ccgggacacg acggcgaact
    12241 cctcgtcgtc gagggcaaac ggctcatgcc gtacctcgcc tcgggcagcg tcggcatcgc
    12301 cgccgtcatc gacgcctacc tcgcccaccg cccggacccg gacctcgaag ccgcgggccg
    12361 cgccctgctc ccggccgcgc tctccgcctt ctacatccag cccggactcc tgcgcggcgc
    12421 ggccggactc ctcatgcacc tggcgacgac accgctgtgc gacgaagcgg agcgagagcg
    12481 cgccctccgg ctccactccg agctgctggg cagccacgcc gtaccgtacg cgggcgaact
    12541 cgccttcccg ggggagcagt tgatgcgcct gtccatggac ctggcgaccg gcaccgccgg
    12601 ttgcctgctc gccctcggca gcgcgcacgg cacccccgcc acgcttccct tcctgccgct
    12661 ccggcggccc gccccggccg cgcacgcggc cccatgaacc ggccccctca ggggtcgtaa
    12721 cgcaccgtcc gacacaactg tccagaaagg acaccatcat ggcgcttctc gacctgcagg
    12781 cgatggagac cccggccgac gagaccttcg gcgagctggc caccggaagc caggtctccc
    12841 tgctgatctg cgagttcagc tcgctcagcg tgacgctctg caccccgtga cacccggccg
    12901 tccggccgcg cggtgatccc accgcccgac cggacggcgc accgccggtc ccgcgcggct
    12961 cgttcgcccg ggaccggcgg catgccgtac ccggccaccg ctccccggga gcgccgcccc
    13021 ggaacacgaa cagccgcagg ccgcgccggc ccggggcgga agggaaccac gtgcgggacc
    13081 gcccacgccc cgaagcggcg tcctccgccg ggcagctcgc ccggcggcgt ccggccgccc
    13141 tcctggtcct cctcctctgc accaccggcg gggcgctcgc cgccctggcg ctgcccgccg
    13201 ccctcggccg cacggtcgac ggcctcatcg acggcggtcc cgtgccctgg tccggactgc
    13261 tgctgtgcgc ggcgctcacc ctcggcgagg ccgggttcga cgcggctgcc gccgtcgtcg
    13321 gagccggcac caccgcccgg ctcaccgcgt ggctgcgcac ctcggccgcg ggccgggtcc
    13381 tggccgccga accccgcaag gtgctggccg tcccggccgg cgacctcacc gcccgcctca
    13441 ccgcgcgcac cgccgacgcc gccgccgcac ccgtgaccgc cgtcaccgcc gcggccggcg
    13501 tcctgctccc ggccggcgcg gtcgtcgggc tcctcctcat cgacccgtgg accgccgcgg
    13561 ccctcctcct cggcgcgccc ctgctcttcg tcctgctgcg caccttcacc cgccgcaccg
    13621 ccgacgccgg atccgactac cagcgcgccc aggccctcat cgcccaccgg ctcaccgagg
    13681 cgctggacgg agccgacacc atccgcgccg cccgcaccgg ggcccgcgaa taccggcgca
    13741 tcctcgaacc gctcggcgcg ctcgccgacc acggccgccg cacctggagc gtgtacgggc
    13801 gcgccaccgg ccagagcgcc ctgctgctgc cgctgctcat gctgctcgtc ctcgccatcg
    13861 ccggggtccg gctcgcggcc ggagcgatcg gcgtcggcga cctgatcgcc gcctcccgct
    13921 acgcgggcct cgccgtcggc gtcggccccc tgaccggcgc gctgggcgcc ctggcccgca
    13981 gccgcgccgc cgcccgcacg ctggaaccgc tcctcgccct cgcgcccctg ccgcaccgct
    14041 ccctggcccc gccgcccgac ggccccggcc gcctggaact gcgcgacgtc ggcgtcgaac
    14101 acgacggccg gccgctgctg agcggagtgc ggctgaccgt tccgggcggt acgtccctgg
    14161 ccgtcgtcgg ccgctccggc tccggcaaat cggtgctcgc cgccgtcgcc gggcgcctgc
    14221 tcgacccgga caccggcacc gtgctgctgg acggcgtacc gctggacggc atggagcccg
    14281 cccggctgcg ccgcgaggtg gcctacgcct tcgaacggcc cgccctgccc ggcgcgacgg
    14341 tcgaggacac catcgccttc ggcccgtgga ccgccccgcc cgacgccgtg cgcaccgcgg
    14401 cccgcgaggc ccgcgcggac gacttcgccc gccggctccc gtacggctac gccaccgcgc
    14461 tcgccgacgc cccgctctcc ggcggcgagc gccaacgcct cggcctggcc cgcgcgttcg
    14521 cccaccccgg gcggctgctg atcctggacg acgcgctctg cgccctcgac acgctcaccg
    14581 agcaccacgt ccagcgcgcg ctggaccgca gggacggccg caccacccgg atcgtcgtga
    14641 cccaccggct ctcctcggcc gcccgcgccg accgcgtcgt atggctggag gacggccgcg
    14701 tacgggccac cggcccgcac cacgagctgt gggccgaccc ggagtaccgg gcggtcttcc
    14761 gcacggcccc gccggacgcg ccgcggcagc gggaggccac cgcccccggc gcgggcccga
    14821 ccaccgctgc gggcccgacc accgccgcgc tccgccccgc ccccgccctc ggaggcgagc
    14881 cccgatgacc gcacccgagg ccgccgagcg gcggaagggc gacggggcgc tcgcccgggt
    14941 catgggcgac gcgcggccct tcctgcgggc ccgcgccgga gccgtcgccc ggctctccgg
    15001 ctggtcgctg ctggagttcg cgcagacctt cctcaccgga tacggcgtgg cccgcgcgct
    15061 cgacgacggc ttcctccccg gccgcccgct gaccggactg ctctggctgg gcgtcgccgc
    15121 ggcggccgtc ctgcccgccc aactcgccac ccgcggcgtc ttcggccgcc tcgccgacct
    15181 ggtcgagccg ctgcgggacg gcctggtgcg ccgcgcggtc tcccgcgccc tcgccgccgc
    15241 cccgcaccgc acggacgcca ccaccgcgtc gctctcccag gtcacccacc agagcgagat
    15301 cgcccgggac agctgggccg gactcgtgct gaccctccgg tcgttcgtgt tcacggcggc
    15361 cggagccgtc gccggcctcc tctccctcgc ccccgccctc ctcgctgtcg tcctgccgcc
    15421 gctgctcctc ggcgcggcgc tgttcctcgc cacgctccgc ccgatggccg cacggcagcg
    15481 cgactacctc accgccgacg agcggtacgc ggcccacgcg ggccgactcg cctcctgcgt
    15541 acgggacgtc gccgccgccg gggccgggga ccgcgtgctg gcggagtccc gggacctggc
    15601 ggacacgcag gtgcgcgccg cccgctcgct ggcccgctgg tccgccgtgc gggtgctggc
    15661 cctcacggtg tgcgggcgct tcccgccgct cctgctgctg ttcgccgcgc cctggctgct
    15721 gcgcggcggg ctcacggccg gcgaactggc cggtgcgctg acctatctca cccaggccct
    15781 cgccccggcc gtccaggcgc tgatgacggt gctcgccacc gtgggcggac gcctcgtggt
    15841 ggtcctggac cgcttcacgg acgcgccggg cccgcccgcc gaggacccgc ctcgggccgc
    15901 cgcccccgcg cgcgtaccgg acgggcgggc cccggtcgcc gagctggacc gggtgagctt
    15961 cgcctacggc cccggcgcgc aacccgtcct ggaccggctc tcgctggcgg tcggcgaggg
    16021 ggagcacctg gcggtcgtcg ggccgagcgg cagcggcaag tccacgctgg ccgccgtcct
    16081 cgcgggcgtg gagccgccca cggagggcgc ggtgcgctgg cgcggacggc ccgcgcgccc
    16141 gtgcgacgcc accgccctgc gcgtcctgct gccccagcag gcgtacgtgt tcaccggcac
    16201 gctgcgggag aacctcggct acctgcgccc cgacgcccgg gagcgggagt tcgccgcgat
    16261 gatcgacgcg ctcggcctgg acccgctgct gacccggctg ggctcgctgg acgcgccggt
    16321 ggagccggcc cggctctccc acggcgaacg ccagctcgtc gcgctgggcc gcgcctacct
    16381 ggccggcccg ccgctcctca tcctggacga ggccaccagc cggctcgacc cggtcgccga
    16441 gacccgcgcc gaactcgccc tggccgcacg ccccggagcc ctggtggtca tcgcccaccg
    16501 gctcagctcc gcccagcgcg ccgggcgcat cctggtggtg gacggcccgc gcacccagtg
    16561 cgggaccgcc gccgaactgc tcgactccag cgagctctac cgcgacctcg ccgggctctg
    16621 gacgcccgac ggcggggcgc ggaccggcct ggacgcgagc gcccggaccc acgtggccga
    16681 acactgaagg cccgacgccg cagcccgcac gccgaagccc gacgccgaag gccgtacgcc
    16741 gaaggccgca cgcgggctca gatccagccc gcctccttcg ccagccggat cgcgtccagc
    16801 cggttgcgcc ctcccgcctt gcggatggcg gcggcgaggt agttgcgcac cgttccggcc
    16861 gtcagatgca gccgcgccgc gatcccggcc accgtctcgc cgccctcggc cagcgagagg
    16921 acgctcaact ccctcggcga cagcggcatg tcggccacct gtaagaggct gaacgccagc
    16981 gactcgtcga tgtgccgccc gccgtcgccc agtttgtgca tcacctcgca caggtcgtcg
    17041 gccgggcggt acttgtcgat gtaaccgcgg gcgcccgcct cgtacgcccg tcgcagcccc
    17101 cggggccgca ggccctcggt gagcacggcc agcgagcagc gtctgccgtg cggcgcggtc
    17161 agcgaaccga tctcctggag gacgtccatc gcgtccggac agtcgagatc ggtcaggagc
    17221 acgtcggcgt cctttccggt cagcgccgaa cgtatctcct cccgttcggc cgtccgtacg
    17281 tcgattccct gcccggtgcc gagcagggag gccagcgaag cgcgccacag cggcacggtg
    17341 tggaccagca gaacggtagt catgaagctg ccctcggtgt tctctcgtgg catgcgcgca
    17401 tggcagaacg cgatggcgcg tgtgcgtccg gtgacgggtt tccagtggaa cgcacggcca
    17461 ttcgggtacg ccgaggaaat ggcggattga cgtggcttgt gggcgcggaa gggggcgctc
    17521 aggggtacac cgggagcgca cgtggccggt tcgtgccgtc gcccccgtac ggcggggatg
    17581 gctcagttca gcagggagcg ggccgcccgc gccttgtgcc ggatcgtcgc ggccatcgtc
    17641 ggctcgatgc cgtcgagcac atccgcgtac tcctccatct cggccgcccc gtgcaggaac
    17701 tcgccccgct gcaccaggag ttgcgcccgc tcgtagcgga gccgggccgg atgggcgggc
    17761 agcaggagcg agaggtcgag cgcccacagc gcgacgtccg tgcgctcggg ccgggccgcc
    17821 gcccaggccc tgacgttgtt caggatgcgc agcacgacct ccaggggccg ggcgggcacg
    17881 agcagggacg gatccatcgg cgcacccgtc gccgccgtca ccagcgactc cgcgtcccca
    17941 ccggtcaacg ggaccccgcc ggcgaacggg tcggcgagca ccggacgcgc cggatcgccg
    18001 aaacccacca cgaagtggcc gggcagcgcc acgccgtaca ccggcgcgcc cgcgcggcgc
    18061 gcgacctcga tccagaccac ggacagcagg atcggcagcc cgcgccgccg ccgcagcacc
    18121 tgctggagga gcgaggagtc cagccgctgg tagtccgccg acgacccggc gaacccgcag
    18181 cgcccgccga ggagttcggc gagcgaggag gcccagtcgg cggccgagcg ggacccgtac
    18241 gggacgagcc ccgccagccg gtccagctcg atctgcgcgg cgtcgatgcc gtacgggtcc
    18301 ggcgcgacct cgcccggcgt caccgggcgc ggctccgacg ggtccaccgg ccccgcctcc
    18361 gcgcccagca gcaggcagag cagggcgagg tccggccgtt cggaccgggc ctcctcggtg
    18421 aactgccgcc gccgctcggc cctgccggaa tcctgcgcac tcatatgcga cccatgctcc
    18481 tgctcgtccc cgctgtccgg ccgcgccgtc ctcgacgccg cccgtgctcc ccgccggacg
    18541 tacgacgccc gccctgcggg ctacccggcg cggaagtggt ggtagcggtg gtgggccgcg
    18601 aagcccatgc cgtcgtacag cgcccgcgca ccttcattgt cctcctccac ctggagccag
    18661 gccgccgagg cgccctcctc cagggcccgg cgcgccagcg ccgccatcac cgcggtggcc
    18721 agcccgcgcc gccggtgctc gggggcgacc tcgacggcca tgaagcccgc ccagcgcccg
    18781 tccaccacca tccggccgat cgccgccggg gccgtgcccg acgcgccgtc ggccgcctcg
    18841 ccgggcacgg cggcgaacca gaccgacggc ccgccgccca gcacccgcag cacgtgcgga
    18901 cccggcgtcc ccaggcgctg gtagcgcgcc agccacgccg cgtccggcgt ccgggtcagg
    18961 cgcaccgggg agacgtccgc gtccaggtcg ccgaccggcg ccagggcggc gatccggacc
    19021 tcggccgaga cctcgcgccg ccacccgtgc cgctccagct ccgcgcagag cacctcctgc
    19081 gtcccctcgg ccccggtggc cgcctggacg tacggcggca gtccccgccg ctcgtagaag
    19141 gcgcggaccc gggcgaacgc ctcggccgcg ggcaggcccg gatcgccgag ggcgagcgcc
    19201 gagttggccc gccgggtgaa gccgccggag gcccgcagcc gccagtcgcc cagcggttcg
    19261 ctctccaccg gcggccaggc gcgcgccgtg acggcggcca gttccggaaa cgaggcggcg
    19321 gggccccggc ggcgggccgg cgcggccggc accgccttgc ccgcgacgag cgacgattcc
    19381 gcgatggtga cagactctcc gttccttcgt gtgatggaga gcacgccgtc gtcccatgat
    19441 gtgagaacgc caaccgtatc ggtgaacccg gcgcccgcgc cgccccccgc ggaccgccgt
    19501 cgaacagata cgcgtttgcc cacgtcagcc ggtgtcacac ggacttccag ccgtccgccg
    19561 atggtgaatt ccacagctct gtccgcccct catgttcgga tcgtgccgga gaacggagat
    19621 actagaggcg ggcatcgacg acgccgcgct cccgcgcgag agccaacgcc ctaccgagga
    19681 ggaacgacag cgtgacctac gtcatcgcgc agccttgtgt cgacgtgaag gacaaggcct
    19741 gcatcgaaga gtgccccgtc gactgcatct acgagggcca gcggtccttg tacatccacc
    19801 cggacgagtg cgtcgactgc ggagcctgtg agccggtctg cccggtcgag gccatcttct
    19861 acgaggacga caccccggag gagtggaagg actactacaa ggcgaacgtg gagttcttcg
    19921 acgacctcgg gtcgcccggc ggcgcctcca agctcggcct gatcgagcgc gaccacgcgt
    19981 tcatcgccgg tctgccgccg cagaaccagt agtcggccac caccaccgcg cagtccggtc
    20041 ccgtacggct cgtcaccgta cgggaccgag gcgttcccgg ggcccgcgcc ccggcgcacg
    20101 gtggccgccc gccgaagaag cacgagaagc acgagaacca cgagaaagca gagtcccgtg
    20161 tccgcagtct cctcccgcct cccggtcttc ccctgggaca ggctcgcgcc ctacaagaag
    20221 accgcccagg cccatccgga cggcatcgtg gacctgtcgg tcggcacgcc ggtcgacccg
    20281 gtgcccgccg tggtccagca ggcgctcacc gccgccgcgg acagccccgg ctacccgacg
    20341 gtgtggggga ccgaggccct gcgcgacgcg atcaccggct ggctggaggg ccgcctgggc
    20401 gcggtcgggg tgacgcacga gaacgtgctg ccggtcgtcg gctccaagga gctggtggcc
    20461 tggctgccga cccagctcgg gctcggcccc ggcgaccagg tggcctaccc gcggctcgcc
    20521 tatccgacgt acgaggtcgg cgcgcggctc tgcggggccg agcccgtcgt ctacgacgac
    20581 cccaccgagc tggacccggc gaggctgcgg ctcctgtggc tcaactcgcc gtcgaacccg
    20641 accggccggg tgctggccaa ggacgagctg acccggatcg tggcgtgggc gcgcgagcac
    20701 ggggtgctgg tcttcagcga cgagtgctac ctggagctgg gctgggacgc cgaaccggtc
    20761 tcggtgctcc acccggacgt gtgcggcgac ggccaccagg gcgtcgtggc cgtccactcg
    20821 ctctccaagc gctccaacct ggccggctac cgggccgcct tcatcgccgg tgacgcggac
    20881 gtcctcgggg agctgctggc gatccgcaag cacggcggca tgatgacgcc cgccccggtc
    20941 caggccgccg ccgtcgccgc gctcggcgac gacgtgcacg tggccgagca gcgcgcccgg
    21001 tacgcggacc gccgcctcgc cctgcgctcc gccctggagg cgcacggctt ccggatcgag
    21061 cacagcgagg cgagcctcta cctgtgggcg acgcgcgacg agccgtgctg gcggaccgtg
    21121 gaacacctgg ccggactggg catcctggtg gcgcccggcg acttctacgg accggcgggc
    21181 gagcgcttcg tccgcgtggc gttcacggcc accgacgagc gggtggccgc ggcggtcaag
    21241 cgcctgtcct gaccgccgcc cgcccgcgcg cggacatgcc gagggcctcg ggagcgcgct
    21301 cccgaggccc tcggcacgag gtgggccggt ggatcagccg atcggcaggc cgttgagcgg
    21361 cagaccgccc acgagaccgc cggtgggcag gccgccgagg cccttggccg gcaccacgcc
    21421 gccctcggtg gcggcgccgg ccgcctcgcc gaccagctcg cccgcctggc cggcggtctt
    21481 gccgacggtc tcctgggcgg ccggggccgc gacggcggcg gtcctgccga cggccttgcc
    21541 ggcggccggc agggcggtgc cgacgagacg cccgccggtg tcgccggcgg ccttggtgct
    21601 ctgctgggcg acgctgtcca cggtgttgcc gaggccggcc ccgtcgagcg cggtgaggcc
    21661 gcccaggtcc gaggtctgcg ggagctctgc ggcgccggcg gcgccggccg caccgaccac
    21721 gggggccgca cccgcggcga tcagcagcgc ggtacgagcg atccgacggg tcagggggag
    21781 ggacatgatg ctccttcgac gggtttcagc tgttcgggat ctggctctgt ccggtgactc
    21841 ggacgccctg acaaccggtc cgggggcggg ggaggttgcg gtgaacgaag gtaaagactg
    21901 agcaatgcgt ccgataatcc gcagcggaag aacccgggca aacaatgcat tccgcagccg
    21961 ccgggagaac cgtcacttcc cttgggcgcc aaggagaacg gtcgtggagg cgcgagctgc
    22021 gcgcagcgcc cccgagaagg tccgagggcc cgctcccaag ggtccgtacg ggtgacggga
    22081 cggactactg agcgagccgg attccgaccg ccgccgtgcc cggttcctca tccttcgtcc
    22141 gttcggtccg ccagcccgac gcggcgtccc agacccggtc cgcgtagctg acgcgctcga
    22201 tccgcagcgc gtccgcccgc gccaccgccc agtgcgccag ctcccagccg cgccgcaccg
    22261 aggtcccgct cttcgcccgc gcctccgcct ccgccgggac cggcaccgac accgcgccgg
    22321 ccgcggcgga acccgccgcc cgcgccgccg gcagcacctc cctgccgaag gcccgcacca
    22381 gctcggcccg cacccggtcc gcgtcgcccg gaccggccgc ggcggccgtg gacggcgtgc
    22441 agtccagcgc cgccggcctg cgcccggtca gcgcggccga cagcagcgcc gcgtccggct
    22501 cgtgccgcgc gtacgccagc gggaaggcgc tgcgctggac gcgctgcgcc gccaccgtca
    22561 gcgggaggcg cgcgtagccg gggacctcgg ccagttcctc gtagaacttc ccggccgagt
    22621 agaccggatc catgatctgc cgttcgctgc cccagccctg cgacggccgc tgctggaaca
    22681 ggcccagcga gtcccggtcc ccgtagggga ggttgcgcag
//
