LOCUS       NZ_ML123034            23736 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4176599
            Orig. end                         :: 4200335
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..23736
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="CDPS"
                     /product="terpene"
                     /region_number="15"
                     /rules="CDPS"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23736
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="CDPS"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20690
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="CDPS"
                     /kind="single"
                     /product="CDPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20690
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[10000:10690](-)"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10690)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="CDPS"
                     /neighbourhood="10000"
                     /product="CDPS"
                     /protocluster_number="1"
     misc_feature    complement(622..636)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            923..1504
                     /locus_tag="EES43_RS18500"
                     /old_locus_tag="EES43_18270"
     CDS             923..1504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966811.1"
                     /locus_tag="EES43_RS18500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18270"
                     /product="hypothetical protein"
                     /protein_id="WP_124269723.1"
                     /transl_table=11
                     /translation="MSLLELIERADERALAAGAVACLDRCLPLLAEPDGPEPLRPLWAS
                     SEHGRDWTARLTAVRTAMEHEPVADGPAAVVRAMLGAAPSDFDRAPLREWADACSLVAL
                     ELHERFDAPDGDPVQDRSHLLKAARAGEDVALGPLAAGELQRQIQIQEILAESGGTAGS
                     GAGMRKALDLSTEGRRVLRAVMSRRARVRG"
     misc_feature    933..946
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.39"
                     /tool="antismash"
     gene            complement(1755..2387)
                     /locus_tag="EES43_RS18505"
                     /old_locus_tag="EES43_18275"
     CDS             complement(1755..2387)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379373.1"
                     /locus_tag="EES43_RS18505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18275"
                     /product="DUF4276 family protein"
                     /protein_id="WP_124269724.1"
                     /transl_table=11
                     /translation="MTYRVLFIGEGSSDNGLVPHVESIAVRKGLEISVTVPDFGLLRPS
                     TGHSVPGKLRAIRALGGTYDLAVVRRDADRGLAQDRRDEIEEAVDAEWPGLQHVAVVPV
                     RMLEAWLLLDEECLRQVAENPRGRVGLDLPKGVAAEKVADPKQLLKDSPAQASEYKGRR
                     LAQFQKRFSQHRLRMLELLDPEGPVACLPSWQGFVKDLDIAFDTLGG"
     gene            complement(2384..3802)
                     /locus_tag="EES43_RS18510"
                     /old_locus_tag="EES43_18280"
     CDS             complement(2384..3802)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018847248.1"
                     /locus_tag="EES43_RS18510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18280"
                     /product="AAA family ATPase"
                     /protein_id="WP_124269725.1"
                     /transl_table=11
                     /translation="MLTRIEVHGFKNLLDLSIDFGPFTCVAGENGTGKSNVFDAIQFLS
                     LLADQSMMEAAQEVRGVHGERQDDPRDLFWKGFAPGSHRMRFAAEMVVPLNTQDDFGRA
                     AKATTTFLRYELEVGYQEPSGLDRFGRLTLLHETLAHITKGKAPQHLRFPHSAKHFRDT
                     VIQGHRSGAPFISTTTESGESIVKIHQDGGSRGQPKPAAASRAPATVVSTITSSDDPTI
                     LAARREMQSWRRLALEPSALRRSDRYVDPHVMGADGSHLPATLFRVAHDTPGADPSQVY
                     ARVAGRLSDLTGIHIRDLDVDQDEVRQLLTVNVHEVAGMTLPARSLSEGTLRFLALRVL
                     LEDPSVRGLICMEEPENGIHPANLNAMVDLVQDLAVDPSEKPGADNAFRQVLINTHSPG
                     VVQLVGNEDLLFADTQIHRSETGALNRALRLRPLAGTWRSAKAARGAFVTKADILPYLT
                     TPVGAQLTLSEGIT"
     cand_cluster    2552..23736
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2552..23736
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[12551:13736](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(12552..13736)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     misc_feature    complement(3818..3832)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
     gene            <3821..4024
                     /locus_tag="EES43_RS18515"
                     /pseudo=""
     CDS             <3821..4024
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477046.1"
                     /locus_tag="EES43_RS18515"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PSGSLKPTGVVLPRRWVAERTFAWLMNSRRRARDYETLPVSNEAV
                     IRWSMITRMSRRLARPRPAGWH"
     gene            complement(3972..4511)
                     /locus_tag="EES43_RS18520"
                     /old_locus_tag="EES43_18285"
     CDS             complement(3972..4511)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114957.1"
                     /locus_tag="EES43_RS18520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18285"
                     /product="hypothetical protein"
                     /protein_id="WP_124272053.1"
                     /transl_table=11
                     /translation="MTEGCAVASVLGMLEVREAAARVRVEGLREEAARLAEVLEAAEIE
                     LNRRVIAREELVEALALSAAETTAVTEADQETVPSPVPGSVVPPWRDGLPVTVLAPDYQ
                     RILAVLEERRSAGKGPVMAREIAVELGLGTTPGKVEGVRSKARRLAERGWLLVEASGMF
                     SASRQAVAVPDAGSSA"
     gene            complement(4638..4961)
                     /locus_tag="EES43_RS18525"
                     /old_locus_tag="EES43_18290"
     CDS             complement(4638..4961)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015925.4"
                     /locus_tag="EES43_RS18525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18290"
                     /product="putative quinol monooxygenase"
                     /protein_id="WP_164493198.1"
                     /transl_table=11
                     /translation="MSEVTVVGRVVAKAGKEAELAQLLQAVIEPTRNEEGSLHYSIQQS
                     IETPEEFIAIERWRHTEDLQRHFRSAHSQHLAAAVESLLAEPIKITTYRELTCGESPHE
                     GDR"
     gene            complement(5044..5892)
                     /locus_tag="EES43_RS18530"
                     /old_locus_tag="EES43_18295"
     CDS             complement(5044..5892)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="EES43_RS18530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18295"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_124269727.1"
                     /transl_table=11
                     /translation="MTDPDRPQPAPYVLDSAARADLEFDRLRTIEQVYDPGTEEILTRV
                     KPAPGWSCLEVGAGAGSIARLLASLAGETGRVVATDTDPRFLRNIAHPGVEVIEHDITA
                     GPLPPGSWDLIHARSVLEHLPDPESVLARLIPSLAPHGQLFAEAIDVSRETLAIAAEHA
                     PDRRAATAFLEFATAVHRLMTLAGAHPELGSTLPVLLAAQGLEGITHQRRHPLVSGGER
                     GFYALSLARLAPSFQDHGLLDTADDRLSSLFDDPSMVFPALPIGAAHGHTPAVGRRQRR
                     T"
     gene            complement(5980..7482)
                     /locus_tag="EES43_RS18535"
                     /old_locus_tag="EES43_18300"
     CDS             complement(5980..7482)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717198.1"
                     /locus_tag="EES43_RS18535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18300"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_124269728.1"
                     /transl_table=11
                     /translation="MDSNRHHTSVLIAGGGPAGLVLALELARRHVDFRIIDAGTGPFPG
                     SRGKGLQPRTLEIFDDLGIIDSVQAEGAPLPPMVAWEEGRIIKEWDVIARGEPTGSTPY
                     AEPLMLPQSRTQELLRERLLRLGHGVAFGARLVGFSQDEAGVLAQVVRADGGTREITAD
                     YLVGADGGGSTVRRILGVRFDREEVDTRPLLVADADIPGLDREHWHTWGSAAGIMTAIC
                     PVARTDYFQVIARFAAGTPDPAPERVRELVAARTGLQVRKVLWSSVFRARAALAEHFRV
                     GRVFLAGDSAHVHSPAGGQGINASIQDAYNLGWKLALAATGQAAPSLLDSYEAERRPAA
                     AEVLGVSTRIHQGAGRVRELAAHRDRTTHHLALGYRGIPPNTEMRPALAEEALHAGDRA
                     PDAPCTDLGGAPVRLFDLFRGPHFTLLVFGSPPIQPVSARGPAVIRVVRVGHDVSDPAG
                     FASRAYAPHGLFLVRPDGYISLATETPSEVTSHLRSLGIHVG"
     gene            complement(7566..8807)
                     /locus_tag="EES43_RS18540"
                     /old_locus_tag="EES43_18305"
     CDS             complement(7566..8807)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735535.1"
                     /locus_tag="EES43_RS18540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18305"
                     /product="cytochrome P450"
                     /protein_id="WP_124269729.1"
                     /sec_met_domain="p450 (E-value: 2.2e-24, bitscore: 84.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPTARIISVLSDEFARDPYAWYPQLRESDPVHYEPGIGAYFLSR
                     HKDVRRVLTEDQIFTTQALRERAEPVMRGRVLAQMTGVEHTAKHRTMIRGYTGPMLENQ
                     IPLIRRNVEELIRPHLRRGRFDLVKDFGQQLAIWVALDSLGLPKDDWQNVHSWFQGVAE
                     FVTSVTLTEERYQHCVQCARRLEDYLRPFIEERRENPGRDVISLMCHTEYESGRMSLHE
                     VTALCHNVLLAATEPADKTLALLFRHLITHPDQMDLVRGDPGLVTNAIAETLRYTPPVQ
                     LIPRRTAESVEISGVAIPAETMVWCMLAAANRDPRVFERPDTFDLQRTDLGPERSFTAA
                     ATHFGFGAGMHSCVGAAFARRELETVVTMLLALMENIGFPEDACYEETGFYSRGPESLT
                     LTFDPTAEGRLLAA"
     gene            complement(8835..9836)
                     /locus_tag="EES43_RS18545"
                     /old_locus_tag="EES43_18310"
     CDS             complement(8835..9836)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="EES43_RS18545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18310"
                     /product="cytochrome P450"
                     /protein_id="WP_164493199.1"
                     /sec_met_domain="p450 (E-value: 4.9e-08, bitscore: 30.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISRRDDLLRVFTDPDLVRLSDAAEALPPPAAISGAARSRAGQPG
                     AEYCATWAVESHRPAIVKQAGLVLDAMETGNNPADLLEQWAAPLTAAVCRDVFGLSFDP
                     QELRNLLIQEEPTGNSAARHPVLHSLTEHLRDDPVRGNAAGAPFKAREQREVDTEPSHT
                     MVSGLLVRCARSLFSALLTGPFTLLLHPKPLRECLRDPVLWQAAAGELRRYHPGTVLGP
                     THIALRDLELHSTLIKAGDAVCASPLGAAWDEEHYPTPAKFDIHRPDAGATYLRTNPGP
                     LVDDGLSRLVLSIVCPALFERFPQLRLAVDEYEIPWRSDLTFIRPACLPVAW"
     misc_feature    complement(9255..9257)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9333..9335)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..10690)
                     /locus_tag="EES43_RS18550"
                     /old_locus_tag="EES43_18315"
     CDS             complement(10001..10690)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) CDPS:
                     CDPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF028025.4"
                     /locus_tag="EES43_RS18550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18315"
                     /product="tRNA-dependent cyclodipeptide synthase"
                     /protein_id="WP_164493200.1"
                     /sec_met_domain="CDPS (E-value: 2.9e-58, bitscore: 195.6,
                     seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVDFLIRPQSENCRRIVDASDHCVLGLSPFNGYYTPCRVEALAQ
                     WAAGHFTRVDVLVPGFEAAHTLTAAGVRPLEAVGRVRRAVNQLRNPAVLALSRAGVSAP
                     EEHVHTWTQLMSRPEYAASRERARAAYRVDPDLRAACRAVARAAVRSIADTEPGEEQID
                     ACVSYPIAELPLIVDSPSIFDVASSVFVYHRRIELAAALLAGPATGLRSAAQQGFVVAE
                     PVLPDGS"
     gene            11314..11565
                     /locus_tag="EES43_RS18555"
                     /old_locus_tag="EES43_18320"
     CDS             11314..11565
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EES43_RS18555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EES43_18320"
                     /product="hypothetical protein"
                     /protein_id="WP_124269732.1"
                     /transl_table=11
                     /translation="MFAEHTLGDGFFAIRVDGRHAVPRFPDCRPLGRLVLTAFGAYTMS
                     NHRRFNRIQPPTGYPFGGGSVSVVPAKERLWPLSLRNP"
     gene            complement(11823..12533)
                     /locus_tag="EES43_RS18560"
                     /old_locus_tag="EES43_18325"
     CDS             complement(11823..12533)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="EES43_RS18560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18325"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_124269733.1"
                     /transl_table=11
                     /translation="MPRLSRPSGRLGIQPGWRCLELGGGAGSVARWLAEQCAPGEVVGT
                     DIGTTLLPRDVPNLSVRRHDVVQEDFPAASFDLVHARALLEHLPERAEVLGKMARWTAP
                     GGWVCVETVMAVHPPSGTRNAYQRCLNAVFTLSENVMGTDQRWGTALPGLLSQAGLTDI
                     GVHCTPGLVGRNGNADAFLRLSLEQIGPALVRARLTTPEELTECTDLLEGGKYTDLALM
                     TLSAWADAPATDSP"
     gene            complement(12552..13736)
                     /locus_tag="EES43_RS18565"
                     /old_locus_tag="EES43_18330"
     CDS             complement(12552..13736)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="EES43_RS18565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18330"
                     /product="terpene synthase"
                     /protein_id="WP_124269734.1"
                     /sec_met_domain="T1TS (E-value: 9.6e-62, bitscore: 208.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRVAPFPVFGFLNQRSLFEVEMPEHFSRLTLYCPIERAENPARS
                     AINESTMAWAAKQGIPSGRERREQFSAMRPGALAAGVVPHGKEEGLAAFADYHTWLFAF
                     DDEYCDDAENSDIDVTEWAAFLARLHRVAETGDIGLLPDNAYAWALRDVASRISACATP
                     TQFCDWADAVRSYFAALVWERSRRRNGEKPQRLDDYLLLRLRNGAMQSSIALLDVAHGY
                     VMPRQLRDTPEARALVEMCAVLVSLDNDIFSHHKESQRGSLEVNLLDVLAAERQATTAE
                     SLQEAVVLRNTVMRRFVELSERTVTPEVGAELQMFVGSLGRWVRANLDFSLVTTRYAGP
                     VRERLVLSPHAPDPRPTEEASALDSAVIGWWWRTPDVAQAGERRRPSRRADPLI"
     misc_feature    complement(13134..13136)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13795..13808
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.29"
                     /tool="antismash"
     misc_feature    14093..14112
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 22.34"
                     /tool="antismash"
     assembly_gap    14478..17793
                     /estimated_length=3316
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            17862..18721
                     /locus_tag="EES43_RS18570"
                     /pseudo=""
     CDS             17862..18721
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374571.1"
                     /locus_tag="EES43_RS18570"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRGDLSDEQWTVLESVLPAAGVRRKVGEPAAVG"
     gene            complement(19000..19521)
                     /locus_tag="EES43_RS18575"
                     /old_locus_tag="EES43_18335"
     CDS             complement(19000..19521)
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024890.4"
                     /locus_tag="EES43_RS18575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18335"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_124269735.1"
                     /transl_table=11
                     /translation="MGAYKERAMSLFMRLDKNHDGNIDPADLGILARGTGDQRSDLARS
                     TGQLVQGFIQDADRNKDSRASLDELAACVDKSMAGTTPETLPTYVRDFASTLFVVMDTD
                     KSGKVDKADFEAYLKAQGASVDVAGREFEMLDRDHDGFLTRDDIQVAAHAFFTAPDGAP
                     AFWLLAAVPA"
     gene            19773..20976
                     /locus_tag="EES43_RS18585"
                     /pseudo=""
     CDS             19773..20976
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611170.1"
                     /locus_tag="EES43_RS18585"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVMKNYPPEFKADAVALYESRPEATIRSVAADLGINPETLRNWVR
                     AAGVSRPRGRRTQEPAQPPTAGG"
     gene            complement(21062..21400)
                     /locus_tag="EES43_RS18590"
                     /old_locus_tag="EES43_18350"
     CDS             complement(21062..21400)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EES43_RS18590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EES43_18350"
                     /product="hypothetical protein"
                     /protein_id="WP_241192470.1"
                     /transl_table=11
                     /translation="MVPHVRRDLNRNDSPADIARAHELSQFAHATVFTGLFFRKEIAAY
                     YEDHGLEMPYEDTARRKIMPEQAEQRILDAFEKDASWGPLFRKTSCGGGVRARGGRLQR
                     ALRHPRAV"
     gene            21898..22656
                     /locus_tag="EES43_RS18595"
                     /old_locus_tag="EES43_18355"
     CDS             21898..22656
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058597.1"
                     /locus_tag="EES43_RS18595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18355"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_124269737.1"
                     /transl_table=11
                     /translation="MLGDDAELTAAVLAAQDGDEGAFRSVYRAVQPRLLGYIRTLVGDP
                     DAEDVASEAWLQIARDLDRFSGDADRFRGWAARIARNRSLDHLRMRSRRPAIGGDESEL
                     TGRPAESDTAGDAMEALDTDRTLSLIAQLPQDQAEAVVLRVVVGLDAKSAAQTLGKRPG
                     AVRTAAHRGLKRLAEILGPEHPDPVRAHGALPPDGCPDHDAGSDAGQEAGAGAELRAVP
                     AQRPVRPGPAAPAGVTPGVTQSRPWTQRDM"
     gene            22635..23732
                     /locus_tag="EES43_RS18600"
                     /old_locus_tag="EES43_18360"
     CDS             22635..23732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610895.1"
                     /locus_tag="EES43_RS18600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_18360"
                     /product="hypothetical protein"
                     /protein_id="WP_124269738.1"
                     /transl_table=11
                     /translation="MDAEGHVMADEHDEWLDKDAAERLLRGEPVVPLGARARGDALRLA
                     RALDAARATGRPSGGELPGEERALAAFRQAARAGSADRTAGRDTAAQTARPGALPSVRI
                     GSAPAEPPRRPRWSRPVRFGLVVSLAGCALGGVAVATGTGILAGPFAGRSAPAPAASVS
                     AAGSPEPLVTGRPADDPSASLRPTPPDEPAPPSIPPERRQPGPSQQAGDPPGPTDRPDA
                     DDDGTDGGGRADGGGDEDAPDDSTEREEHEDGWGQGSSENWYEKSLKACKALHGGTLDG
                     RDRRRLRELAKGEDDLERFCSRLLGGAGDGGDHGGGDGDPGPGGPGGPGGNEGGSLPPV
                     SFLSMPPGDAGSLVGPPCAGLAKTC"
ORIGIN
        1 ccgcgggcgt gccgtcgaag ggggccatcg acatctcgaa gcccggagcg gccaagctga
       61 tcgacgagct gctggacgag tacaccgagc tgttcggcgg caagtactgg cacctggggg
      121 ccgacgagta ccaggcgctc accgtgcgcg accccgcctc ctccttcccg cagctccagc
      181 gggccgccga gaagaagtac ggccccgacg cctcgatcga ggacctggcc accggctggc
      241 tcaacgaccg cgcggccgtc gtcgtcccga agggcaagac cgccaaggcg tggaacgacg
      301 ggctcttccg caagacgaag atcaaggccg acgaggacat cgagatcgag tactggaccg
      361 gcaaggagat cggcgcgcgc ccgccgcagg agtacctggc cgccggctac aaaatgctca
      421 atctcaacga cgagttcctc tactacgtgc tcggcgagcc caacgacttc acctacccga
      481 cgggccggcg catctacgag cagtggacgc cgctggtgat gcgcggaacc cagcccgtcg
      541 cggagcgcta ctcgccgcag atcctcggcg gccggttcgc cgtctggggc gacctggcga
      601 acgcccagac cgcccagcag gtggccgacg gcatcaggat gccgctggtg gcgacctcgc
      661 agaagctctg ggacccgcgc aagcccgcgc tgagttggac gcagttccag caactggccg
      721 cccgcacggg cagcgtggac tgagcgcggc gcgtcgcccc ggtccggcgc gggccggccc
      781 gaacgcgggg ccgtggtcac cttttggcca cggccccgcg tttttcgtgc gcaacggccc
      841 gcggaatccc ctgttctgcc atgatggcgg tgacgatatt cagccagtcg gcgcagtacg
      901 cggtaaaccg agggagacgc cgatgagtct gctggaactg atcgaacgcg ccgacgagag
      961 agcgctggcc gccggcgccg tggcctgcct ggaccgctgc ctgccgctgc tggccgagcc
     1021 ggacggaccc gagccgctgc gcccgctctg ggcgagcagc gagcacgggc gggactggac
     1081 cgcgcgcctc accgccgtcc gcaccgccat ggagcacgag cccgtggccg acggcccggc
     1141 cgccgtggtg cgcgccatgc tgggcgcggc cccgtccgac ttcgaccgcg cgccgctgcg
     1201 ggagtgggcc gacgcctgct ccctggtggc cctggagctc cacgaacggt tcgacgcccc
     1261 ggacggcgac ccggtgcagg accgctcgca cctgctgaag gccgcgcgcg ccggcgagga
     1321 cgtggccctg gggccgctcg ccgccgggga gttgcagcgc cagatccaga tccaggagat
     1381 cctcgcggag agcggcggca cggcgggcag cggcgccggc atgcgcaagg ccctcgacct
     1441 ctccacggag ggccgccggg tgctgcgcgc ggtgatgtca cgccgggccc gcgtccgggg
     1501 ctgagcggca ggggagccgg ggccggggct gtatgcggga ctggccggcc cctctccgcg
     1561 ccggaccacc gggtcacgcc ccgcgctgtc gcggttgccc gccccgcccg gcagaggccg
     1621 tcaaccggcg tgcgccgtcc gctctgccgc acggcaccct caggggctgg aacgtgtgat
     1681 gtcagggcgg ttggcgccgg agacccggcc ccttctggag gcacacgaca ggggagccga
     1741 tacgcagggg gtggtcatcc accaagggtg tcgaacgcga tgtcgaggtc cttgacgaaa
     1801 ccctgccacg acggaagaca ggcaacggga ccttcgggat cgaggagttc gagcatgcgc
     1861 agccggtgct gagagaagcg cttctggaac tgggcgaggc ggcgcccctt gtactcgctt
     1921 gcctgcgccg gcgagtcttt gaggagttgc ttcgggtcgg cgaccttttc cgccgctacg
     1981 cccttgggaa gatcaagacc gacacggccg cgagggttct cggcgacctg gcgcagacat
     2041 tcttcgtcga ggagcagcca ggcttcgagc atgcggacgg gcaccacggc gacgtgctgg
     2101 aggccaggcc actcggcgtc cacggcttcc tcgatctcgt ccctccgatc ctgggcaagg
     2161 ccccggtcgg cgtcccgtcg caccacagcc aggtcgtagg ttcctccgag tgcgcggatc
     2221 gccctcagtt tgcccggcac ggagtgtccg gtcgacggcc ggagcagacc gaagtcgggg
     2281 acggtgaccg agatctcgag ccccttgcga acggcaatgg attcgacgtg gggtacgagg
     2341 ccgttgtcgc tgctgccctc tccgatgaac aggacgcgat aggtcacgtg atcccctcgc
     2401 tcagcgtgag ctgcgctccg acgggtgtcg tgaggtacgg caggatgtcg gccttcgtca
     2461 cgaaggcacc gcgtgctgct ttcgcggacc gccaagtccc cgccagcgga cgcagtcgca
     2521 gtgcccggtt cagggcgccg gtttcgctcc tgtggatttg ggtgtcggcg aagagaagat
     2581 cctcgttgcc gacgagctgc acgacccctg gtgaatgcgt attgatcagc acctgccgga
     2641 acgcgttgtc tgcgccgggc ttttcggaag ggtccacggc aaggtcctgc accaggtcga
     2701 ccatggcgtt gaggttcgcc gggtggatgc cgttctcggg ctcctccata cagatcagcc
     2761 cccgcacgga cgggtcttcg agtagaacgc gcagggccag gaaacgcagc gtgccctcgg
     2821 agaggctgcg cgcgggcagc gtcatcccag ccacttcgtg cacattgacc gtgaggagct
     2881 gtcggacctc gtcctgatcg acatccagat cacggatgtg gattccggtg aggtccgaga
     2941 ggcgtcccgc gaccctggcg tacacctggc tgggatccgc gccgggagtg tcgtgggcca
     3001 cgcggaaaag tgttgcgggc aggtgagagc cgtcagcacc catcacgtgc gggtcgacgt
     3061 accggtcgga cctgcgtaga gcggagggtt ccagggcgag tcgtcgccag gactgcatct
     3121 cacgacgagc cgcgaggatt gtcgggtcgt cactgctggt gatggtcgag acgaccgtcg
     3181 caggcgcgcg ggatgccgcc gccggcttgg gctggcccct gctgccaccg tcctggtgaa
     3241 tcttgacgat cgactcaccg gactcggtgg tcgtcgagat gaacggtgcg ccgctgcggt
     3301 gcccctggat gacggtgtca cggaagtgct tggcgctgtg ggggaaacgg aggtgctgcg
     3361 gagccttgcc cttggtgatg tgggccagcg tttcgtggag gagggtcaag cgtccgaaac
     3421 ggtcgagacc ggacggttcc tgatagccga cttccagttc gtaccgcagg aaagtggtgg
     3481 tggccttcgc ggcacgaccg aagtcgtcct gtgtgttgag aggtacgacc atctcagcgg
     3541 cgaaccgcat ccggtgactg ccaggcgcga agcccttcca gaagaggtcg cgggggtcgt
     3601 cctgacgctc gccgtgtacg ccccggacct cctgggccgc ctccatcatc gactggtcgg
     3661 cgagcaggga gaggaactgg atggcgtcga agacgttcga cttgccggtg ccgttctccc
     3721 cggcgacgca ggtgaaagga ccgaagtcga tggacaggtc caggaggttc ttgaacccgt
     3781 ggacttcgat gcgggtcagc atgtggtgtc cggatgttcg ccgagcggat ccctcaagcc
     3841 tactggtgtg gtgctcccca ggcgctgggt ggcagagcgc acgttcgcgt ggttgatgaa
     3901 ctcccgccgc cgggcccggg actacgagac gttgccggtc agcaacgagg cggtgatccg
     3961 gtggtcgatg atcacgcgga tgagccggcg tctggcacgg ccacggcctg ccggctggca
     4021 ctgaacatcc ccgatgcctc cacgaggagc cacccgcgtt ccgccaggcg cctggccttc
     4081 gaacgcactc cctcgacctt ccccggcgtc gttccaaggc ccagctccac cgcgatctcc
     4141 ctggccatca ccggtccctt gcccgcggac cgccgctcct ccagcacggc cagaatccgc
     4201 tggtagtcgg gcgcgagaac ggtcaccggc agcccgtccc gccagggcgg caccaccgac
     4261 cccggcaccg gtgagggcac cgtttcctga tccgcctcgg tcacggccgt cgtctcggcg
     4321 gcggacaatg ccagagcctc gaccagctcc tcccgcgcga tcacccgccg gttcagctcg
     4381 atctccgcag cctccaacac ctcggccaac cgcgcggctt cctcccgcag gccctccacc
     4441 cgtacccggg cagccgcctc ccgcacctcc agcattccca gcaccgacgc caccgcgcac
     4501 ccctcggtca tgaagcggac aagacgccgc atgcctccct cactccgagc gaaaccatgc
     4561 ctgaccagca gaaatcaaga gatcacgttc ggttgagata cggcttctca ggtcttgtcc
     4621 gtgcagtctc cgtggggtca gcggtcgccc tcgtggggac tctcaccgca tgtcagctcc
     4681 cggtaagtcg tgatcttgat cggttccgcc aggagtgatt ccaccgcagc ggcgaggtgc
     4741 tgggagtgcg cgcttcggaa gtggcgctgg aggtcttcgg tgtgtcgcca ccgctcgatg
     4801 gcgatgaatt cctccggggt ttcgatgctc tgctggattg agtagtgcag gcttccctcc
     4861 tcgttccggg tgggttcgat gaccgcctgg agcagttgtg cgagttctgc ctccttgccc
     4921 gccttggcga cgacccggcc cacaaccgtt acttcactca tcggcttcgc ctctctcggt
     4981 gttccgtttg cgtgttgttc cgttcggatg ggcgctctcc gcccttcctg gcggaccggc
     5041 tcttcaggtt ctccgctgtc gccgtccgac cgcgggggtg tgtccatggg cggcgccgat
     5101 ggggagtgcg gggaagacca tggacgggtc gtcgaacagg gaggagagcc ggtcgtccgc
     5161 ggtgtcgagc agaccgtggt cctggaacga cggtgcgagg cgggcgagcg agagcgcgta
     5221 gaaaccgcgc tctccaccgg agacgagggg gtgtcgccgc tggtgggtga tgccctccag
     5281 accctgggcg gcgaggagca ccgggagggt gctgccgagt tcggggtgtg ctccggcgag
     5341 tgtcatcagc cggtgcaccg cggttgcgaa ctccaggaag gctgtggccg ctcttctgtc
     5401 cggggcgtgt tcggcggcga tggcgagtgt ctcgcgactg acgtcgatcg cttcggcgaa
     5461 gagctgcccg tgtggtgcca gcgaggggat cagccgggcc aggacggatt cggggtccgg
     5521 cagatgctcc agtacggatc tggcgtggat cagatcccag gaacctggtg gcagagggcc
     5581 tgcggtgatg tcgtgttcga tcacttcgac cccgggatgt gcgatgttcc tcagaaatcg
     5641 cggatcggtg tcggttgcca ccactcttcc ggtctctccg gcgagagatg ccaggagacg
     5701 ggcgatactg cccgctcccg cgccgacttc gaggcatgac cacccaggtg ccggcttcac
     5761 ccgggtgagg atctcctcgg ttccggggtc gtagacctgc tcgatcgtgc gcaggcgatc
     5821 gaattcaaga tccgctcggg cggctgaatc cagaacgtag ggggcgggtt gcggacggtc
     5881 cgggtcggtc atggtctgcc tctctggttc ctccgggccc gacgagcggt gcagggccgc
     5941 cgacgcgagc acgagcagcc cggatcaggg ttccgccggt catccgacat gtatgccgag
     6001 tgagcgaaga tggctggtca cctcacttgg agtctccgtg gccagcgaga tgtatccgtc
     6061 cggtcgtacg aggaacaggc cgtgcggtgc gtacgcgcgg gaggcgaacc ctgcggggtc
     6121 cgagacgtcg tggccgacgc gcaccacgcg gatcaccgcg ggaccccggg cgctgacagg
     6181 ctggatgggc gggcttccga agacgagaag ggtgaagtgg ggtccgcgga agaggtcgaa
     6241 gagacgtacc ggggctccgc ccaggtcggt gcacggggca tccggtgcgc ggtcccccgc
     6301 gtggagggct tcctcggcca gggcggggcg catctccgtg ttgggcggga tgccccggta
     6361 tccgagtgcc aggtggtgcg tggtgcggtc gcgatgtgcg gccagttccc tgacccggcc
     6421 cgccccttga tggatgcgag tgctcactcc cagtacttcc gccgcggccg gccggcgctc
     6481 cgcctcgtag gagtccagaa gcgagggtgc tgcctgcccg gttgccgcga gcgccagttt
     6541 ccagcccagg ttgtaggcgt cctggatgct cgcgttgatg ccctggccgc ccgccgggga
     6601 atgaacatgc gcggagtcac cggccaggaa cacccggccg acacggaagt gctccgcgag
     6661 tgccgctcgt gcccggaaga ccgatgacca cagcaccttc cgcacctgca atcccgtgcg
     6721 ggcggccacc agttcgcgga cccgctccgg ggcggggtcg ggtgttcctg ccgcgaaccg
     6781 tgcgatgacc tggaagtagt ctgttctggc gacgggacag atcgcggtca tgatgccggc
     6841 cgcgctgccc caggtgtgcc agtgctcgcg gtccagtccg ggaatatcgg catcggccac
     6901 gagcaggggc cgggtatcca cttcttcgcg gtcgaacctc acgcccagga ttctccgtac
     6961 ggtgctgccg cccccgtccg ccccgaccag atagtcggcc gtgatctccc gcgtacctcc
     7021 gtcggcccgg acgacctggg ccagcacccc ggcctcgtcc tgggagaatc cgacgagccg
     7081 cgctccgaac gcgacgccgt gtcccagccg cagcagtcgc tcgcgcagca gttcctgggt
     7141 acgcgactga ggaagcatca gcggttccgc gtagggcgtg gacccggtgg gctcgccacg
     7201 ggcgatgaca tcccactcct tgatgatcct tccctcctcc caggccacca tcggcggcag
     7261 cggcgctccc tccgcctgta cggagtcgat gattccgagg tcgtcgaaga tctccagggt
     7321 gcgcggctgg agacccttgc cccgtgatcc cggaaagggg cccgtgcccg catcgatgat
     7381 ccggaagtca acgtgccgac gggccagttc caacgccagg accagtccag caggtcctcc
     7441 tccggcaatc agaacagatg tgtggtggcg attactgtcc acggcatgtc ccctttccgg
     7501 tcctccgtca tcgtgatgcg gaggaggccg cagccggctg tatgcggttt cccctttctg
     7561 gtggttcagg ccgccaggag ccgtccttcc gcggtgggat cgaaggtcag ggtgagggat
     7621 tcagggccgc gggagtagaa gccggtctcc tcgtagcagg cgtcctcggg gaagccgatg
     7681 ttctccatga gggccagcag catcgtcacg accgtctcca gttccctgcg cgcgaatgcg
     7741 gccccgacgc acgagtgcat gcccgcgccg aacccgaaat gggtcgcggc ggcggtgaag
     7801 gaccgttcgg gaccgaggtc tgtgcgttga aggtcgaagg tgtcgggccg ctcgaagaca
     7861 cgcgggtcgc gattggcggc ggcgagcatg caccacacca tggtctcggc gggtatggcg
     7921 acaccggaga tctcgacgct ctccgctgtc ctgcggggga tcagttgcac aggtggtgtg
     7981 tagcggagcg tctccgcgat ggcattggtc accagcccgg gatcgccgcg gaccaggtcc
     8041 atctgatcgg ggtgcgtgat cagatgccgg aacagcaggg ccagtgtttt gtccgccggt
     8101 tcggtcgcgg cgaggagcac gttgtggcac agagccgtga cctcgtgcag gctcatcctc
     8161 ccgctctcgt actccgtgtg gcacatcagc gagatcacat cccggccggg gttctcgcgc
     8221 cgttcctcga tgaagggccg cagatagtcc tccagccggc gggcgcactg gacgcagtgc
     8281 tggtatcgct cctcggtcag ggtgacgctc gtcacgaatt cggccacccc ctggaaccag
     8341 gagtgcacat tctgccagtc gtccttgggc agtccaagac tgtccagcgc gacccagatg
     8401 gccagttgct gtccgaagtc cttcaccaga tcgaaccggc cgcgccgcag atgggggcgg
     8461 atgagctcct ccacgttgcg gcggatgagc gggatctgat tctccagcat cggcccggtg
     8521 tatccgcgga tcatcgttcg gtgcttcgcg gtgtgctcga cgccggtcat ctgtgccagg
     8581 acgcgaccgc gcatgaccgg ctcggcgcgt tctcgtaggg cctgggtggt gaatatctgg
     8641 tcctcggtca gaacccggcg aacgtctttg tgccggctca ggaagtaggc gccgatgccg
     8701 ggttcgtagt ggactgggtc gctctcccgt agctgggggt accaggcgta cgggtcccgg
     8761 gcgaactcgt ccgacaggac actgatgatg cgggcagtcg gccgcatggt gttctcctct
     8821 caccgggttg gctgtcacca ggccacaggc agacaggcgg gacggatgaa cgtcagatcg
     8881 ctcctccagg gaatctcgta ttcatccacg gccaggcgca gttgtgggaa gcgctcgaac
     8941 agggcggggc agacaatgct gagaaccagc cggctcaggc cgtcgtccac caggggccca
     9001 ggattcgtgc gaaggtacgt ggccccggcg tccggacgat ggatgtcgaa cttcgccggg
     9061 gtggggtagt gctcctcgtc ccaggcagcg ccgaggggcg acgcgcatac cgcgtccccg
     9121 gccttgatca gagtgctgtg tagttccagg tctctgagcg cgatgtgggt ggggccgagc
     9181 accgtgcccg ggtggtagcg gcggagttcc cctgctgccg cctgccacag cactggatcg
     9241 cgcaggcatt cacgtaacgg tttggggtgg agcaggagag tgaatggtcc ggtcagcaat
     9301 gccgagaaga gtgacctcgc gcaccggacg agtaagccgc tcaccatggt gtgcgacggt
     9361 tcagtgtcga cctcccgctg ttcgcgggct ttgaagggcg caccggcggc attaccgcgg
     9421 acggggtcat cccggaggtg ctctgtgagc gagtgcagga ccgggtgcct ggcagccgaa
     9481 tttcctgtcg gctcttcctg gatcagaagg ttccgcaatt cctggggatc gaatgacagc
     9541 ccgaagacat cgcggcacac ggcggctgtt agcggcgccg cccattgttc cagcagatcg
     9601 gcagggttgt tcccggtttc catggcgtcc aggacgagac ccgcctgttt tacgattgcg
     9661 ggccggtggg attccaccgc ccacgtcgcg caatactcgg cgcccggctg cccggcccgc
     9721 gagcgcgctg ccccgctgat cgcggccgga gggggaagcg cttcagcggc atcgctcagc
     9781 cgcacgaggt ccgggtcggt gaatactcgc aggaggtcgt cccggcggga gatcatccac
     9841 agccaggatc cgcccggaag ctctaccggg cagaccggct gccgtcggcg tgcccagtgg
     9901 atcacgggcg gaggcgtgcc cagggggccc agcacaaagg gaaacctcaa cggtacttcc
     9961 ggtgtcctcg ccggcatcgg gagctgcctg agctgtctca tcacgaacca tccggcagta
    10021 cgggctcggc caccacgaac ccctgttgtg cagctgaccg cagcccggtc gccggaccgg
    10081 cgagcagggc cgcagcgagc tcgatccgcc ggtggtagac gaacacagaa gaagccacgt
    10141 caaagatcga cgggctgtcc acgatcagcg gcaactcggc gatcggataa ctgacacagg
    10201 cgtcgatctg ctcctcgccg ggctccgtat ccgcgatgga ccggaccgct gcccgggcaa
    10261 ccgcccgaca ggccgccctg agatcgggat cgactcggta tgccgctctg gcccgctcgc
    10321 gcgacgccgc gtactcgggt cggctcatca gctgagtcca ggtgtgcacg tgctcctccg
    10381 gcgcggacac accggcacgc gacagcgcca gcaccgcggg attcctgagc tgattcacgg
    10441 cccgcctcac acgtcccacc gcctccagcg gcctgacacc agcggcggtg agggtatgcg
    10501 ccgcctcgaa cccgggaacg agaacatcga ccctcgtgaa atgtccggcc gcccactggg
    10561 ccaacgcctc cacccggcac ggtgtgtaat agccgttgaa cgggctcaga cccaagacgc
    10621 agtggtcgga ggcatcgacg atccgacggc aattctcgct ctgtggtcga atcaggaaat
    10681 ccacggtcac caccgcttac ctgcatctgt atgccacgtt ctcatgccaa tacctgttcc
    10741 cggtcgccag gtctgaaagt ccgccatgaa gtgggcggcc cgaagagaga aggccgtcac
    10801 gtcagaattc acaccgaatt ctctgcccga acggctcagg tcatttggag acgaaacctg
    10861 tcatttcgtc acggcggccc agcgagcgcg tcagtacaac tcgacggtcg agtgcgcatc
    10921 acccgtgatc actccgcagt gcgccgacgc ctcctcgccg tgctgctaca cactacggga
    10981 tgttatgaac attcgataga ccttattgct gtattaattt aggcccgggg aggctaacct
    11041 cgatgggcag tagaaatcgt tattgtgttc gttaatggaa atttagttcg aatgtgcttt
    11101 ccctcggctg catttcgagc ccgtcggcac gatcctcgcc atccacggat cttcctcacc
    11161 gaggtccgct cggctcggcg gcaccacccg cacgtcggca accgtgtggt gatgtcgacg
    11221 cctgcgcctg gggtctcgcg ccttggcacc ggtcgtgcgt gctgcccacc gcgcccccga
    11281 tggccaggcc acttcggccc cgatctcccc gggttgttcg cggaacacac cctcggcgac
    11341 ggcttcttcg ctattcgtgt cgacggcagg cacgccgtgc cgcgcttccc cgattgccgg
    11401 cccttgggcc ggctggtact caccgccttc ggcgcgtaca ccatgtccaa tcaccggcgg
    11461 ttcaaccgca tccagccgcc cactggatac cccttcggcg gcggcagcgt cagcgtcgtc
    11521 cccgcgaagg agcgcttgtg gccgctgtcg ctccgcaacc cgtgacgatc tgccgctgat
    11581 cacagacgtc cacgcgttcg gggtcgccca ccccgaacgc gggatcgcct taccgactac
    11641 tccgtctgag caccggagaa gacgcatgcg gctcgtgcgc gcccctgatc gtggcgatcg
    11701 acaccgagat ctcccgccgg cggacgagca cccgagcatg atcaagcccg tgacctgccc
    11761 gagcaccctg cccccgcacc acgccggcgc ccgtgacctg tggatttcag gatgggatca
    11821 gcttatgggg agtcagtggc gggtgcgtcg gcccaggcgg acagggtcat gagggcgagg
    11881 tcggtgtact ttccgccttc cagcaggtcc gtacactccg tcagttcttc gggtgtggtg
    11941 agacgtgcgc ggaccagggc tggaccgatc tgctccaggg agagccgcag gaaggcgtcg
    12001 gcgttgccgt tcctgcccac caggcccggg gtgcagtgga cgccgatatc ggtcagacct
    12061 gcctgtgaga ggagtcccgg cagcgcggtg ccccatcgct ggtcggtgcc catcacgttc
    12121 tcggacaggg tgaacacggc gttgagacag cgctggtagg cgttccgggt gccggacggg
    12181 ggatggaccg ccataaccgt ctccacgcac acccagcctc ccggtgcggt ccagcgcgcc
    12241 atcttgccga ggacttcagc tcgctccggc aggtgttcca gcagtgctcg ggcatggacg
    12301 aggtcgaagg aggccgccgg aaagtcctcc tggacgacat cgtggcgtcg gacggacagg
    12361 ttgggcacgt cccggggcag cagggtggtg ccgatgtcgg tgcccacgac ctcccccggg
    12421 gcgcactgct cggccagcca gcgcgcgacg gagccggcgc cgcctccgag ttcgaggcac
    12481 cgccagcccg gctggatgcc gagacgtccg gacggccggg acaggcgggg cagccgtccg
    12541 gagcgcgtcc atcagatgag cgggtccgcc cgccgggacg gccgtcggcg ttcacccgcc
    12601 tgggcgacgt caggagtgcg ccaccaccag ccgatcacgg cggaatcgag ggctgatgcc
    12661 tcctccgtcg gccgcggatc cggtgcgtgc gggctgagaa cgagacgctc ccgtaccgga
    12721 ccggcatagc gcgtggtgac aaggctgaaa tccagattgg cgcgcaccca tcggccaaga
    12781 ctccccacga acatctggag ttcggcaccg acctccggcg tcaccgtacg ctcactcagt
    12841 tcgacgaagc ggcgcatcac cgtgttgcgc agcactacgg cctcctggag cgactccgcg
    12901 gtcgttgcct gccgctccgc tgccagcaca tccaggaggt tcacctccag agagccgcgc
    12961 tgggactcct tgtgatgcga gaagatatcg ttgtcgaggg agacgaggac cgcgcacatc
    13021 tccaccagag cccgggcctc gggcgtatca cgcaactgcc tcggcatcac gtatccgtgg
    13081 gccacgtcca acagcgcgat actgctctgc atcgcaccgt tgcgcaggcg cagtaacaag
    13141 tagtcgtcca gcctctgggg cttctcaccg tttcgccgcc gcgaccgctc ccagaccaga
    13201 gcggcgaagt aggaccggac ggcgtcagcc cagtcgcaga attgcgtggg tgtcgcgcat
    13261 gcggagatgc gggaggctac atcacggagc gcccaggcat aggcgttgtc cggcaggagt
    13321 ccgatgtctc cggtttcggc cactctgtgg agccgcgcca ggaaagccgc ccactcggtg
    13381 acatctatgt ccgagttctc ggcgtcgtcg cagtactcgt cgtcaaacgc gaagagccag
    13441 gtgtggtaat cggcgaaggc ggcgagccct tcctctttgc cgtgcggcac aacgcccgcc
    13501 gcgagagctc ctggccgcat cgccgaaaac tgttcccgac gttcccggcc ggaagggatt
    13561 ccctgcttgg cagcccaggc catcgtgctt tcattgattg ccgatctggc cgggttctca
    13621 gctctttcga tgggacagta gagagtcagc cgactgaagt gttcaggcat ttcaacctcg
    13681 aaaagtgatc tctgattgag gaatccgaag acgggaaacg gtgcaaccct gttcacgggt
    13741 tgcaaggttg atgtccggtg ggagaggagc caaacctgga cacttgatgt gctttatcat
    13801 gatttttagt cattgaggct cttggagcct cacgctcaag acctacggct ggagcagtgg
    13861 cgtactactc caaggtgaat agcgctgctt cggggaaatc tggtcggctc tgcatcacgc
    13921 gcgtctggtt cgcccgcccg ggccgtgacg gaagagcacc ggtatgtcta tcgcgtcgcg
    13981 gtagcgcggg ggcttgaggt cttttgtctt cttctccgga ggcgcaggga ttcactgtct
    14041 cagcaacagg ccgctggcca gtcactcagg ggggcgcgca caaagtctgg gcaagcggcc
    14101 gagtgcccct cgcgcggtga tcctcggcgg tatcgagaat tcttccatcg tgtgactgat
    14161 agctggatgg gggggagttg tgcgctatgg tcgcggcgag ctattgagac ggtcagcccg
    14221 aacaggtcgg ggggcccgcc actcttgtgc tgcgaacgcg tcgccgcacc gtcgatgcgg
    14281 tgggccccgg gagtgcacgc ccggggctcg ctcactgatc cctgccttgg tgggggagac
    14341 tgcttctcgg atgccgacgc cccgcgcctg ccgctcccag gagcctgggc gagcatcagg
    14401 cggtccgcgt gacgcgcaag agggcctcgg caggctggct gtgcagccga tgaagcaccg
    14461 actcacgtga gtaggtgnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    14941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    15961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnntaaaaga tcagtaggcc gtgttttggg
    17821 ttcgggtccc ggcgttgtcg cggaaccgtg atgatcgcgg tgtggggcgt ggggatcttt
    17881 cggacgagca gtggacggtg ttggagtcgg tgttgcctgc ggcgggtgtg cgtcgcaagg
    17941 tcggggaacc ggcggcggtt ggttgatggg gttcggtggc gggtgcggac gggcgctccg
    18001 tggcgtgacc tcccgcccgg gtaagggcct tggcagaccg tgtacgggtt gttccggcgc
    18061 tggcagcgcg aaggtgtgtg ggcgcgggtg ctgacgttgt tgcaggcgcg ggcggatgcg
    18121 gcgggatcgt gtgggaggtg agtgtcgact ccacggtctg ccgggctcac cagcacgcgg
    18181 ccggtgcacg ccgggacggg gccgggcaga aggagccgcc cggcggaatg gtgcgcgagc
    18241 cggacgacca tgggctgggc cgatcgcggg gcggattcgg cacgaagatt catctggcgt
    18301 gcgagcaggg ccagaagccg ctgtcgttgc tggtgacagc gggacagcgc ggcgacagtc
    18361 ggcagttcgt gccggtcctg gagacgatcc gggtgccgcg gctgggcccg gggaggccaa
    18421 ggcggactcc ggtgcgggtg cgggccgaca aggcgtactc gtcggccgcc aaccgcgcct
    18481 acctgcgcag gcggggtatc cgctgcgcga tcgcggagcc agccaaccag gtccgcaatc
    18541 gcgtgcggcg gggccgctcg ggcgggcgcc cgcctgcgtt cgacggtgag gactacaagg
    18601 cacgccacgc ggtggagtgc ggcggctcaa gcgcaacagg gccgtggcga tgcggttcga
    18661 gaagctcgcc gtgcggttcg aggccgtcgt cgtggtggcc gcgatcaacg aatggctctg
    18721 agcacgctcg gaaatcgcga tgacccgctg gcgcgtctac aactcggcga gccaggcact
    18781 gagcggttgg aggggctggc ggccggggtc cggcagcgat cggcgccgct gccggaccgc
    18841 ctcgtccgga aggccgccga aatgccagcc gcgcacctcg tgcccgtcct cgcgttcgcc
    18901 gccggtgcgg tcctgcggtt ggcagggaga ggacccctgc gaaccgaatg ccgcacgggt
    18961 aggcgaaggt ccttcagggc cccgtcacgc ggtcgcgccc tacgcgggaa cggcagcgag
    19021 gagccagaac gccggggccc cgtccggggc ggtgaagaag gcgtgagccg ccacctggat
    19081 gtcgtcgcga gtgaggaatc cgtcgtggtc gcggtcgagc atctcgaact cgcggccggc
    19141 gacgtcgacg ctggccccct gggccttcag gtacgcctcg aagtcggcct tgtcgacctt
    19201 gccggacttg tcggtgtcca tgacgacgaa cagcgtggag gcgaaatcgc ggacgtacgt
    19261 gggaagggtc tcgggagtcg tcccggccat cgacttgtcc acgcaggcgg ccagttcatc
    19321 caggctcgcc ctgctgtcct tgttccggtc ggcgtcctgg atgaagccct ggaccaactg
    19381 cccggtgctc cgggccaggt ccgaccgctg gtcacccgtg ccccttgcga ggattcccag
    19441 gtcggccgga tcgatgttgc cgtcgtggtt cttgtcgagc cgcatgaaca ggctcatggc
    19501 cctctccttg tacgcgccca tggtcgtgct ccttgagtgt gaagggtgct gctgccggtc
    19561 ttcctgacga acgtagcccg gcgggcattg gcgcttcggg agcactcaac cgtattcccc
    19621 cgatcgggtg gacgggtgac gctcctgcgg ggccgggtcc ggagggggat ggatcctgcc
    19681 tggccttcag ggtcaacgag gatgacgggc cttgacccct gatgttggac acacgagaca
    19741 ctggatcctg aggatctgag aacggacatc tggtggtcat gaagaactac ccgccggagt
    19801 tcaaggcgga cgcggtcgcg ctgtacgagt cgcggcccga agcgacgatc aggtcggtcg
    19861 ccgctgatct ggggatcaat ccggagacgc tgcggaactg ggtgagggcc gcaggagtaa
    19921 gccgtccgcg gggacgccgg acgcaggaac cggcccagcc gccgaccgct ggaggctgag
    19981 aacgcggcct tgcggaagaa ggtccgtgag ctggaggagg aacgcgagat cctccgcaaa
    20041 gcggcaaagt atttcgccgg ggagacgcgc tggtgaaccg cttccagtgt gtcgccgatc
    20101 tccaccgccg ctacggcgtg aagcggctgt gccgcatcct cggcatcagc cgctcgagct
    20161 tctactactg gcgccggaca gctgcggacc gggccgcccg gcaggcggcc gacgcgaggc
    20221 tggccgccct gatacgggcg gtgcaccagg actcggacgg cacgtacgga gccccgataa
    20281 tcactgccga actccgcggg acgagcggag aggcactcaa ccacaagcgc gtcgccagga
    20341 tcatgcgggc gttcggcatc gaaaggggtc cggttgcgcc gccggcaccg caccaccgtc
    20401 gccgacccag tggcggccaa ggcgcaggac ctgatcggcc gcgacttcac cgccacggct
    20461 ccgaacacga agtacgtcgg cgacatcacc tacctgcccc tcgagggcgg gaagttctgc
    20521 tacctggcgg ccgtcatcga ccttgcctcc cgccgtctcg ccggctgggc gatcgccgac
    20581 cacatgcgaa ccgacctggt gaccgacgca ctggccgcag cggtccgcac ccgcggcagc
    20641 ctggcaggat cgatcatgca caccgaccac ggagctcagt acacaagcag ggccttcgcc
    20701 gaagcctgca ggtcagcagg ggtgcggagg agcatgagcg cggtcgggtc cagcacggac
    20761 aacgcactcg ccgagtcctt cgacgcgacc ttcaaacgcg agaccctgca aggacgaaag
    20821 agctggccga acgagcgtga ggcccgcctc gacgccttcc gacggctcaa ccgctacaac
    20881 acccgacgcc gacactccca cctcgggcaa cgatcaccaa tcgccttcga gaacgcctac
    20941 caccgcacac caactacgcc ggcacgagcc gcataacccg tgttcaggat tcggggtcaa
    21001 ggcccactcg ggcttgaccc atgccttctc acaccgctcg atccgctcgg gcgggcagat
    21061 gtcacacagc tcgcggatgc cgaagtgccc gttgtagtcg gcctccccgt gcgcgtacgc
    21121 cacccccgca gctcgtcttg cggaacagcg gaccccagga ggcgtccttc tcgaaggcgt
    21181 cgaggatgcg ctgctcagcc tgctcgggca tgatcttgcg ccgggcggtg tcctcgtagg
    21241 gcatctccag accgtggtcc tcgtagtacg cggcgatctc cttgcggaag aacaggccgg
    21301 tgaagacggt ggcgtgcgcg aactgcgaca gctcgtgcgc gcgggcgatg tccgcggggg
    21361 agtcgttgcg gttgaggtct cggcgaacgt gaggcaccac tcgccgggct acacgatgtc
    21421 ccagtacggc aagcgccggg tggagggggc tcggaagctc gcgtcgggga ccgcgcagcg
    21481 catcggcctg gggcgcatcg ggtgaccgtc cgacgcgttg gtcacgccgt tggtcacgga
    21541 ggcaatttct gccggtcacg cggccctgtg aaaggaactc gttggcgcgt tggtcacgga
    21601 ggggataagg ggcccactaa accgcaggtc aggaggctaa atgttggagc gacgaccggg
    21661 gccgccaccc cccacaggag aggccccggc cgtcttccac ggggtcgcag cacgaccccg
    21721 tactcatctc agcgccgcca ccgcgttttc tgtcacaccg cccggcggac cgggaattgt
    21781 tgcgagttgt acaagacatg gacgcggccc ccgccgagca cgtagcgtgc tgattcgtgc
    21841 agagtggcgc ggcagtggtg accagctgcg tttgaggaca gcagggcggg ttggggagtg
    21901 ctgggggacg acgcggagct gaccgccgcg gtgctcgcgg cgcaggacgg ggacgagggc
    21961 gccttccgtt ctgtgtaccg cgcggttcag ccacggctgc tgggctacat acggacgctg
    22021 gtgggagacc cggacgccga ggacgtggcc tccgaggcgt ggttgcagat agcccgtgac
    22081 ctcgaccggt tcagcggtga cgccgaccgg ttccggggct gggcggcgcg gatcgcgcgc
    22141 aaccgctcgc tggaccatct gcggatgcgc agccgccgcc ccgccatcgg cggcgacgag
    22201 agcgaactga ccggcaggcc cgccgagtcc gacaccgcgg gcgacgccat ggaggccctg
    22261 gacaccgacc gcaccctgtc cctcatcgcc cagctgccgc aggaccaggc cgaggcggtg
    22321 gtgctgcggg tggtcgtcgg cctggacgcg aagagcgcgg cacagaccct cggcaagcgg
    22381 cccggcgccg tacggaccgc cgcgcaccgc ggcctcaagc ggctggccga aatcctcggg
    22441 ccggagcacc cggacccggt ccgcgcccac ggcgcgctcc cgcccgacgg ctgtcccgac
    22501 cacgatgccg ggagcgacgc aggtcaggag gcgggagccg gagcggagtt gcgcgccgta
    22561 ccggctcagc ggcccgtgcg gcccggcccg gcggcgcccg ccggggtcac tcccggtgtg
    22621 acgcaatcac gaccgtggac gcagagggac atgtgatggc cgacgagcac gacgagtggc
    22681 ttgacaagga cgcggcggag agactgctcc gcggcgagcc ggtcgtaccc ctcggcgccc
    22741 gcgcccgcgg cgatgccctc cggctcgccc gcgcgctcga cgcggcccgc gcgaccggcc
    22801 gtccctccgg cggtgaactc ccgggcgagg aaagggcgtt ggctgcattc cggcaggcgg
    22861 cccgcgccgg ttccgccgac cggaccgccg ggcgcgacac cgccgcccag accgcccggc
    22921 ccggggcgct gccttcggtg cggatcggct ccgcgcccgc ggagccgccc cgccgcccgc
    22981 gctggagccg cccggtccgt ttcggcctgg tcgtctccct ggcgggctgc gcgctgggcg
    23041 gagtcgccgt cgccacgggt acggggatcc tcgccgggcc gttcgccggc cggagcgcgc
    23101 ccgcgcccgc cgcctccgta tcggcggccg ggagccccga gccgctggtc accgggcggc
    23161 cggccgacga cccgtccgcc tcgctccggc cgaccccgcc cgacgagccc gccccgccct
    23221 ccatcccgcc cgagcgccgg cagcccggcc cgtcgcagca ggccggagac ccgcccggac
    23281 cgaccgaccg gccggacgcc gacgacgacg gcaccgacgg cggtggccgc gcggacggcg
    23341 gcggcgacga ggacgccccg gacgactcca ccgagcgcga ggagcacgag gacggctggg
    23401 gccagggttc gtcggagaac tggtacgaga agtccctcaa ggcgtgcaag gcccttcacg
    23461 gcggcaccct cgacggccgg gaccggcgcc ggctgcggga gctcgccaag ggtgaggacg
    23521 atctggagcg cttctgctcc cggctcctcg gcggcgccgg ggacggtggc gaccacggag
    23581 gcggcgacgg cgatcccgga cccggcggac ccggcggacc cggtgggaac gagggcggtt
    23641 cgctgccgcc tgtctccttt ctctccatgc cgcccggtga cgccggctcg cttgtgggcc
    23701 cgccgtgcgc cggcctcgcg aaaacttgct gacctg
//
