LOCUS       NZ_ML123034            21122 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2605278
            Orig. end                         :: 2626400
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..21122
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="13"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21122
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21122
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11122](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11122)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            454..1557
                     /locus_tag="EES43_RS11250"
                     /old_locus_tag="EES43_11175"
     CDS             454..1557
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961039.1"
                     /locus_tag="EES43_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11175"
                     /product="hypothetical protein"
                     /protein_id="WP_241192373.1"
                     /transl_table=11
                     /translation="MTATATEGSGRERAPAATALHVLPEVLRTALDWTNAHRAEFALPA
                     DALDAHTDVNATFKPLGELAQLCVTIRRDTEPGTPEHTAADGLVAFAWEQVERGALLLE
                     LLRAEPFASYPYEIYAAFAAEGLRHEGFERLAHTLGATRSWAHIEQHPNRQLGLVNSER
                     RVGTVAHADSGTVLSRTWLGGLAEPWMFEGPSGYALTHTVFHLTDWGGAPDRLPESLAA
                     YLRTWLPAWTDGCLESGHWDLAGELLAVAAVLPGPPAPALLDTAWPVLADVQDAGGSIP
                     ETGPPARRNGTSSAPGGGTTSPVAGATSPVAGATSPVAGASDPYPFYDCYHSTLVTAFA
                     AALSLRALRSPPSLRSAGAQGRERQTA"
     gene            1554..2477
                     /locus_tag="EES43_RS11255"
                     /old_locus_tag="EES43_11180"
     CDS             1554..2477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380542.1"
                     /locus_tag="EES43_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11180"
                     /product="hypothetical protein"
                     /protein_id="WP_124268608.1"
                     /transl_table=11
                     /translation="MSGIQQIHDVGAKALGWLHEHRDGFRLEDDPDPETGYLDRFKPLG
                     ELALICKVIFREGVAGSQQSALSHQLLDHAWHRLLDSGERLLTGQRHEPLSPIPLEVYV
                     PFRELGFRHPELEVALRLNHRLSSSAALEVLPVRRLGLSAIERRFGVEPNTPETAALAH
                     TWLARRPEPWTVEGHIAYDVTHTVFHLTDWGEKPAGLPVDVADYLALWLPAWLDDWLDL
                     GRWDLLGELLVVDACLPEPTLDAAAWQGFAQAQQPDGAMPVAGDMPEGDEEEVFDLVYH
                     PTLVAAFASALALSRALSDLTSPAPA"
     gene            2612..3637
                     /locus_tag="EES43_RS11260"
                     /old_locus_tag="EES43_11185"
     CDS             2612..3637
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006141204.1"
                     /locus_tag="EES43_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11185"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_164493334.1"
                     /transl_table=11
                     /translation="MLADAARTVDAPDVVIAVSRYGERTVHRGGVAPAGPVPRELLRYE
                     LGSASKPFAGLLLARLVAQDRVRYEDRAADLLAPGHPVHPAVRAITLRHLMTHTSGLPA
                     LPADFYPQAVPRWSTDPYRGYPADRVVRAFLRARPRHRPGTRWHYSNFGVSVLGHTLAA
                     ATGTPWEILLHQQVLGPLGLAATLLRPGPADTDATGHRRDGSPVPALDPGGFTAAGAVR
                     STPLDLLTFLEAHLARPPGPAPADPAAPADQTLAAALAEVVRPVLRRGWRHGHTHTLTW
                     FRHPSPYGPVLFHAGATLGQQVFLGFRPESGLAIAATATRRVRRGVPFVATAYGLLTET
                     L"
     gene            complement(3841..4725)
                     /gene="rsmI"
                     /locus_tag="EES43_RS11265"
                     /old_locus_tag="EES43_11190"
     CDS             complement(3841..4725)
                     /EC_number="2.1.1.198"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsmI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609092.1"
                     /locus_tag="EES43_RS11265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11190"
                     /product="16S rRNA (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="WP_206430033.1"
                     /sec_met_domain="TP_methylase (E-value: 9.2e-31, bitscore:
                     105.9, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVTGTTGTLVLAGTPIGDVADAPPRLAAELERADVVAAEDTRR
                     LRRLTQALGIHTSGRVVSYFEGNESARTPELVEALTGGARVLLVTDAGMPSVSDPGYRL
                     VAAAVEKDIRVTAVPGPSAVLTALALSALPVDRFCFEGFLPRKAGERLGKLREVADERR
                     TMVFFEAPHRLDDTLAAMAEVFGADRRAAVCRELTKTYEEVKRGPLGELAVWAADGVRG
                     EITVVVEGAADSGAEELDAEELVRRVRVREEAGERRKEAIAAVAAAAGLPKRDVFDAVV
                     AAKNAERAAPKKP"
     gene            4779..6545
                     /locus_tag="EES43_RS11270"
                     /old_locus_tag="EES43_11195"
     CDS             4779..6545
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000030 - mannosyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006493 - protein O-linked glycosylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961043.1"
                     /locus_tag="EES43_RS11270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11195"
                     /product="phospholipid carrier-dependent
                     glycosyltransferase"
                     /protein_id="WP_124268610.1"
                     /transl_table=11
                     /translation="MTSTAPEAQRGQDAGNPYGEQPAPWQRRLRRFGHVPRPELPLRDR
                     LDPPYTRPGRPFWSVLGVGPGLADRLVRWSAWGGPLLVALVAGVLRFWKLDQPHALIFD
                     ETYYAKDAWALVNQGYEGAWPKDVDKLILKNPDAVPIPTDPGYVVHPPMGKWIIGLGEQ
                     MFGFTPFGWRFMVAVLGTVSVLLLCRIGRRLFRSTFLGCLAGVLLTVDGLHFVMSRTAL
                     LDLILMFFVLAAFGCLLADRDQARRKLAAALPVDAEGVLRPDAGIAESLRLGWRPWRIA
                     AGVMLGLAFATKWNGLYVLAAFGVMAVLWDVGARRTAGAVRPYAAVARRDLVPAFVSTV
                     PVAVVTYVASWTGWIVTDKGYYRDWAATEGRGGAWSLLPDWLRSLWHYETQVYDFHVGL
                     TSGHTYESNPWSWIVLGRPVSYFYEEQTGCKESSTGKCASEVLAIGTPLLWWAACVALA
                     YVLWRWFFRRDWRAGAIACGVAAGWLPWFLYQERTIFLFYAVVFVPFLCLAVTMLIGAL
                     LGPAAGTGTRAELGLTPPDPTGERRRTLGAIAAGVLVLLIIWNFVYFWPLFTGTSIPED
                     LWRDRMWLDTWV"
     gene            <6594..>6722
                     /locus_tag="EES43_RS31255"
                     /pseudo=""
     CDS             6594..>6722
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611170.1"
                     /locus_tag="EES43_RS31255"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDGAVFPSDDGARYASKEFATVPGRFGVIRLRGAVGASADNAA"
     gene            complement(6881..8644)
                     /locus_tag="EES43_RS11275"
                     /old_locus_tag="EES43_11205"
     CDS             complement(6881..8644)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EES43_RS11275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EES43_11205"
                     /product="hypothetical protein"
                     /protein_id="WP_124268611.1"
                     /transl_table=11
                     /translation="MYMVQEPVYEPYRSAEIPRYEAGERAARHILSAAFAPEVIQSVMQ
                     SPLLATAQVTSAQIQAGLWTARKDSLAPLIEAVPRKGGEVDRILGEYCLRHAKSPLHAV
                     PMAMRDFILLWFAAAFIRVDGRMLDLCGSTSCLMMAVDYVAARDDAGGGGHAAYATAAS
                     EGLACLGGTSVTQALRDTVVVDAVLRARDITTTATSRITDPNGFVDAAGGPVTPKEYMR
                     ARWWDAAMVPYHRLPMSTPGYRHVTDELGTFTAADRCGAIKRAIDCAIRYNEIVDIVPD
                     CANGESFNEVLLALASRGGHAVYGYADALARVTDDVLRCDCGASGHEEAAEIAMGDCLF
                     YLLTTRYQMRKQLQCLSAAGGAIQRAYAQRPPGARLEAVASTTLRPGNLLHSDAWEPLW
                     KPVEAAHRMPGRWANHLARRAARRSLPADTAACDRDRCETVITSLLVDCDNAPNHSLPT
                     LAKRWGDVFDGVLTAAVADHALLRQHSLALRELIERIWLHCVVDGDDGTPHPAERADEQ
                     LAMDTTQALFATYGLPPTEGWAIRRAFSGVATSAVELSGLSPYSRMTDGISRILLDTTR
                     TRRGEVGDRGR"
     misc_feature    complement(7202..7204)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8630..8643)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            complement(8979..10004)
                     /locus_tag="EES43_RS11280"
                     /old_locus_tag="EES43_11210"
     CDS             complement(8979..10004)
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-enyl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948231.1"
                     /locus_tag="EES43_RS11280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11210"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_124268612.1"
                     /transl_table=11
                     /translation="MNTATPHQAHPARPTPATKRVLLASPRGWCAGVDRAVAVVEKALE
                     LYGDPIYVRHEIVHNKYVVQTLERKGVIFVERTEEVPEGSIVVFSAHGVAPAVHAEAAE
                     RKLATIDATCPLVTKVHKEAIRYANEDYDILLIGHEGHEEVIGTTGEAPDRITLVDGPV
                     DVAHVEVRDESKVVWLSQTTLSVDETMETVDALKTRFPNLLSPPSDDICYATQNRQIAV
                     KKLAEDAQLVIVVGSRNSSNSQRMVEAALRAGADTAYLVDFADEIDEAWLQGVTTVGLT
                     SGASVPDVLVDSVLKWLAERGYTDVETVRTADESITFSLPKELRRNLRTQPVDDPTASP
                     S"
     gene            complement(10001..11122)
                     /locus_tag="EES43_RS11285"
                     /old_locus_tag="EES43_11215"
     CDS             complement(10001..11122)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349428.1"
                     /locus_tag="EES43_RS11285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11215"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_241192374.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.9e-51, bitscore:
                     171.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSTGFHTAPAYSAHASAAFQGGEVRQRVSQILDDFVEGKITAA
                     RTGALPEEVAEYVGDFLNAGGKRIRPLLCVLGWHAAGGAGGVDQAARVGAALEMFHAFC
                     LIHDDVMDHSATRRGRPAMHRALAAHHSKDRTRQAATDIGTAAAILMGDLALIWSDELL
                     HASETALDARQRTRVLPLIDTMRNEVLYGQYLDLTATSQPTPDVGLALRVIRYKTAKYT
                     IERPLHIGAALAGAPDTLLAQLSSFAVPLGEAFQLRDDLLGVFGHPVETGKPALDDLRE
                     GKHTCLIALTLRNAPRAQADQLRLLVGCPTLTEDQAHIARSIITASGAPDTVEEMIRDR
                     YARASSALAAAPVPADIRASLQDMAHQAVWRTT"
     gene            complement(11119..12270)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="EES43_RS11290"
                     /old_locus_tag="EES43_11220"
     CDS             complement(11119..12270)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349429.1"
                     /locus_tag="EES43_RS11290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11220"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_124268613.1"
                     /transl_table=11
                     /translation="MTSIDLGPPTPRPAPLTTRTPARRRPTRQLNVGTVPVGGGAPISV
                     QTMTTTSTADVDATLRQIAEVTAAGCDIIRVAVPSQDDADVLPAIVAKSPIPVIADIHF
                     QPRYVFQAIDAGCAAVRVNPGNIKKFDDKVGEIAQAATAAAVPIRIGVNAGSLDPRLLA
                     KHGSATPEALVESALWECSLFQEHGFRDLKIAVKHHDPMTMIAANRLLAAQCDYPLHLG
                     VTEAGPAFQGAIKSAVAFGILLGEGIGDTIRVSLSDDPVQQVKAGCHILASLGLRPRRL
                     EIVSCPGCGRLQVDIHKLAGRVEAAFDGFPHPLRIAVMGCVVNGPGESREADLGVSCGN
                     GKGQIYRQGQVLRTVPESKIVEALMDEALALTARCDDEAGDQP"
     gene            complement(12267..14105)
                     /locus_tag="EES43_RS11295"
                     /old_locus_tag="EES43_11225"
     CDS             complement(12267..14105)
                     /EC_number="2.2.1.7"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349430.1"
                     /locus_tag="EES43_RS11295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11225"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_241192375.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.4e-82,
                     bitscore: 274.7, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-05, bitscore:
                     22.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMRTSLLSGTTAEAGGALRALAAEQLPVLAAEIREFLVEKVCAS
                     GGHLGPNLGMVELTLALHRVFESPRDALVFDIGHQAYVHKLLTGRREAFDSLRQAGGLT
                     GYPSRSESVHDLVENSHASTALSYADGLAKARQLAGESDRAVVAVIGDGAMTGGLAWEA
                     LNNLGAAKDRPVIIVLNDNGRSYAPTTGALAEHLNVLKSGGAEACRNLFTDLGFTYFGP
                     VDGHHTGEIDQVLRRARALSRPAVVHVMTVKGKGYRPAETDEADCLHAVGTVDPATGRP
                     IPARTAEAPSWTSVFGQELCRIAAAHPEVVAITASMLSPTGLLPMQQTFPERVFDVGIA
                     EQHAVTSAAGLAMGGYHPVVAIYATFLNRAFDQVLMDVALHQLPVTFVLDRAGITGPDG
                     PSHHGMWDLAVLSTIPGLRIAAPRDATRLREMLREATTVQGGPTVLRLPKATVGSDIEA
                     LTRMDGLDILHRTHRGPLDVLLVPTGPLAAAALDAAVLLEEQGLGVTVADPGWVLPVNP
                     ALPALAARHRVTVTVEDGLRTGGFGTALAQACTDTAVAAPVISCGLPTAFIPHAPRTHL
                     LTQAGLDGTGLFTAAMAHLRPDPTEHAPAPTPRSAR"
     misc_feature    complement(13401..13403)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14025..14027)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(14319..14334)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            15079..16695
                     /locus_tag="EES43_RS11300"
                     /old_locus_tag="EES43_11230"
     CDS             15079..16695
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046488.1"
                     /locus_tag="EES43_RS11300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11230"
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="WP_124268614.1"
                     /transl_table=11
                     /translation="MRSGAKVVVIGGVFVLVAGGLGYGAYAVLGGEGGGFASAPVKTGP
                     PSAAETADASAAFFKAWAAGDAAGAARLTDNETAAEPVLTSYGKTAHIGKVRITPGAAV
                     GAKVPYTVEATVSYRGKSQPLAYESELSIVRGRTTGKALVDWVPGVVHPRLSEGATLRT
                     GEAESPQIEAVDRDGVVLTKEKYPSLGPILDSLRQKYGATAGGTPGIETWVEPADEKRP
                     GTTLLTLAKGKPGTVQTTLDAGAQAAAERAVRKYQQASVVAVQPSTGAIQAVANNPATG
                     FNAAMQGQQAPGSTMKIVTAALLLEKGLVTANGAAECPKEVVYQGAKFHNLDRFDLPDG
                     STFTQSFARSCNTAFIKLIDDVKDDSALAKEARDVFGLGLDWKTGVVSTDGSVPEEAGG
                     VAAAQYIGQGTVQMNALNMASVTATARTGTFRQPVLVPQSLDDRKLAVTERSLSPSARR
                     QLTTMMRATAAWGTGAKAMASVGGDKGAKTGSAEVDGQATSNSWFTGFSDDLAAAAVVQ
                     TGGHGGDAAGPIVAEVLRAGS"
     gene            complement(16874..17254)
                     /locus_tag="EES43_RS11305"
                     /old_locus_tag="EES43_11235"
     CDS             complement(16874..17254)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609098.1"
                     /locus_tag="EES43_RS11305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11235"
                     /product="hypothetical protein"
                     /protein_id="WP_124268615.1"
                     /transl_table=11
                     /translation="MRNLVRAAVALTFTAGAVLATGAGAQAGAPDTRDAQDAYAGCQSG
                     YVCIYPGASWNGNRPEATYYQYGVYNLSNQTGTHRVFNNQTGGASVQLCTGYNGVGCGA
                     KMPTWTYWDVDLTPINSIKLSA"
     gene            complement(17414..18496)
                     /locus_tag="EES43_RS11310"
                     /old_locus_tag="EES43_11240"
     CDS             complement(17414..18496)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609099.1"
                     /locus_tag="EES43_RS11310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11240"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_124268616.1"
                     /transl_table=11
                     /translation="MLRIHFTAQDLEYVRIAPRPDPLWEILSSVCRLQTDEGRIAFGPW
                     RRAVAPQLRGAGGGTDRAIALALRSLVPFGPYIPDFLTPAVDGGNVDLRQGVDRVLSTP
                     RSRLRHEITLLAQSEPRMRPFAAEQLAVGDAAALRALGGLLTAYDAAFVAPYRPWIDAA
                     VASDVAWRSRRLAAGGTRALLETFRPMARWSPPVLEVTYPVERDMHLAGRGLLLVPSYF
                     CWRKPITLVDEALLPVLVYPVAKPIHPPAVPGGSAAVTSLARLLGPTRAALLYEMAVRG
                     CATTSELADAVGCSLPNTSQQLAILREAGLAAGRKEGRYVLHQPSPLGRRLLETTTGGR
                     LPGGAVDAWLPRPEPATVSP"
     gene            complement(18770..19636)
                     /locus_tag="EES43_RS11315"
                     /old_locus_tag="EES43_11245"
     CDS             complement(18770..19636)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009336218.1"
                     /locus_tag="EES43_RS11315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11245"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_124268617.1"
                     /transl_table=11
                     /translation="MTKAGSTPSHPSSSVQQAREELAGRLRDLRRDAGISGRELAVRCG
                     WSDAKASRIGNARTPPSDADIQAWCRACDAADRAPDLIAASRQSADAHVQWRRLQRTGL
                     RRVQESTESLYQRTRVFRVYVSDVIPGFLQTPGYATALLSSIAEFRGTPDDVTDAVEVR
                     MRRNAVLTNGAHRFSFVLEESVLRHRLCTVETMAAQLGHLLGVMNLQNVAVGIVPFSAR
                     RTMWSMPTFTMFDDARVHADTLDAASTLVQPSQVDLYRRAFGRLSQESVRGAAARSLVA
                     SALASLG"
     gene            complement(19633..>19914)
                     /locus_tag="EES43_RS11320"
                     /old_locus_tag="EES43_11250"
                     /pseudo=""
     CDS             complement(19633..>19914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955956.1"
                     /locus_tag="EES43_RS11320"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11250"
                     /product="DUF6879 family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VTQYIRWEHYVTHANVTAGEEVRWLPRRLATDIPLPGNDFWLFDG
                     ALLRVHHFSGDGAVVEDEITSDAETVKLCSSAFEAVWERAVPHRLYAI"
     gene            complement(20119..20589)
                     /locus_tag="EES43_RS11325"
                     /old_locus_tag="EES43_11255"
     CDS             complement(20119..20589)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153588.1"
                     /locus_tag="EES43_RS11325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_11255"
                     /product="hypothetical protein"
                     /protein_id="WP_241192376.1"
                     /transl_table=11
                     /translation="MFGSKKKLTINMFSSQKKLNDVMAQLRPDLSRESLGVGPDFPGVA
                     PNPFLSSDARQRNAELRTGALALGILVDWREVNSNPRVVLMFDVETVGGRSFRGIADED
                     LTITELTRLAPGQTLPVRYRPAVRDHYVALARDADPVHVQRLSEEIASRKRT"
     misc_feature    20903..20914
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(21026..21039)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 catggcggcc cccgggacca ccgggccgca cagcgacctc ggccccaccg gatcacccag
       61 cggcctcggc gccaccggac cgcagagcga ggtccgggcc ggccgaccgc accaggaacc
      121 cgacgccgcc tggctggagg acgccccctg gcaggcgctc acgcaccagc tctcgatcct
      181 cgcccccctc gccgtcccgg ccgtcccctc ggccgtgcag cgggccgcgg ccggccggac
      241 ggtcgacctg tcacgcggct tcgtccgcgc ggtccgcagg cgcgactggc tccaggcggc
      301 cggagccggg cgctggctca cggcgatcgg ctccgagccg gcgacgctgg ggctggcccg
      361 cggcctcgac ttcgtcgagc tgatgggcgg ccacgatccc cgggtggccc tgcacgtgcg
      421 ggccgcgcgc ctgatggccg aggcggcacg gcggtgacgg cgaccgcgac cgagggctcc
      481 ggacgggagc gggccccggc cgccaccgct ctccacgtcc tgcccgaagt cctgcgcacc
      541 gcgctggact ggacgaacgc gcaccgcgcg gagttcgcgc tgcccgccga cgccctggac
      601 gcgcacaccg acgtcaacgc cacgttcaag ccgctgggcg agctggcgca gctgtgcgtg
      661 accatccgcc gcgataccga accgggcacc ccggagcaca cggcggccga cggcctcgtc
      721 gcgttcgcct gggagcaggt cgagcgcggc gcactgctgc tggagctgct gcgcgccgaa
      781 ccgttcgcct cctaccccta cgagatctac gccgccttcg ccgccgaggg cctgcgccac
      841 gagggcttcg agcggctggc gcacacgctc ggcgcgaccc gctcctgggc ccatatcgag
      901 cagcacccca accgccagct cggcctggtc aactccgagc ggcgggtcgg cacggtggcc
      961 cacgccgact ccgggaccgt cctgtcccgg acctggctgg gcgggctcgc ggaaccgtgg
     1021 atgttcgagg gcccctcggg ctacgccctg acccacaccg tcttccacct caccgactgg
     1081 ggcggcgcgc ccgaccggct cccggagagc ctggccgcct atctgcggac ctggctgccg
     1141 gcctggacgg acggctgcct ggagagcggc cactgggacc tcgccggcga actgctcgcg
     1201 gtcgcggccg tcctgccggg cccgcccgca ccggccctgc tggacacggc ctggccggtg
     1261 ctcgccgacg ttcaggacgc gggcggctcg atccccgaga ccggtccgcc ggcgcggagg
     1321 aacgggacgt cgtccgcacc gggaggcggg acgacctcgc cggtcgccgg ggcaacctca
     1381 ccggtcgccg gggcaacctc accggtcgcc ggggcgtctg atccgtaccc cttctacgac
     1441 tgctaccact cgacgctcgt gacggccttc gccgcggccc tgtccctgcg ggccctgcgg
     1501 tcgccgccgt cactacggtc cgcaggcgcc cagggccggg aaaggcagac cgcatgagcg
     1561 gcatccagca gatccacgac gtcggcgcga aggccctggg ctggctgcac gagcaccggg
     1621 acggcttccg gctggaggac gaccccgatc cggagaccgg ctacctcgac cgcttcaagc
     1681 cgctgggcga actggccctg atctgcaagg tcatcttccg cgagggcgtg gcgggctccc
     1741 agcagtccgc gctgtcgcac cagctcctcg accacgcctg gcaccggctg ctcgactccg
     1801 gtgagcggct gctgaccggc cagcgccacg aaccgctctc gcccatcccg ctggaggtct
     1861 acgtaccctt ccgcgagctg ggtttccgcc accccgagct ggaggtggcg ctccggctca
     1921 accaccggct gagcagttcg gcggcgctgg aggtgctgcc ggtgcggcgg ctgggcctca
     1981 gcgcgatcga gcggcgcttc ggtgtggagc cgaacacgcc ggagaccgcg gcgctcgccc
     2041 acacctggct ggcccggcgg ccggagccct ggaccgtcga gggccacatc gcctacgacg
     2101 tcacgcacac cgtcttccat ctgaccgact ggggcgagaa gcccgcgggc ctgcccgtcg
     2161 acgtggcgga ctacctggcg ctgtggctgc cggcgtggct ggacgactgg ctggacctgg
     2221 gccgctggga cctgctgggc gagctgctgg tggtcgacgc ctgcctgccc gaaccgacgc
     2281 tggacgcggc ggcctggcag gggttcgcgc aggcccagca gccggacggg gcgatgccgg
     2341 tggcgggcga catgccggag ggcgacgagg aggaggtctt cgacctcgtc taccacccga
     2401 cgctcgtggc ggccttcgcg tcggcgctcg cgctgtcccg cgccctgtcc gacctcacct
     2461 ccccggcccc ggcgtgaacg ggcccaccga ggcggggctg tccggggcgg ggccctccgg
     2521 gccggggcct acgggcgcgt cgcgggccgc ccaccgcacc ggccccacgc tcgacgcgcc
     2581 cgacgcgccc ggcgacccgg ccaccgcccg tctgctcgcc gacgcggcgc gtaccgtcga
     2641 cgcgccggac gtggtgatcg cggtcagccg gtacggggag cgcacggtcc accggggcgg
     2701 cgtcgcgccc gccgggccgg tcccgcgcga gctgctgcgc tacgagctgg gctcggcgtc
     2761 gaaaccgttc gccgggctgc tgctggcgcg gctggtcgcc caggaccggg tgcggtacga
     2821 ggaccgggcg gcggacctgc tggccccggg ccacccggtg caccccgccg tgcgcgcgat
     2881 caccctgcgc catctgatga cccacacctc ggggctcccg gccctgcccg ccgacttcta
     2941 cccgcaggcc gtgccgcgct ggtccacgga cccgtaccgc ggttacccgg ccgaccgggt
     3001 cgtccgggcc ttcctgcggg cccgcccgcg ccaccggccg ggcacccgct ggcactactc
     3061 gaacttcggc gtctccgtcc tcggccatac cctggcggcg gccaccggca cgccgtggga
     3121 gatcctgctg caccagcagg tgctgggccc gctgggcctg gccgcgaccc tgctgcgacc
     3181 gggcccggcg gacacggacg ccacgggcca ccggcgcgac ggcagcccgg tgcccgcgct
     3241 cgaccccggc ggcttcacgg cggccggggc ggtgcgctcg accccgttgg acctgctgac
     3301 cttcctggag gcgcaccttg cccggccccc gggccccgct ccggcggacc cggcggctcc
     3361 ggcggaccag accctggccg ccgcgctggc ggaggtggtc cggccggtgc tgcggcgcgg
     3421 gtggcggcac gggcacacgc acacgctgac ctggttccgg cacccgtccc cgtacggccc
     3481 ggtcctcttc cacgcgggtg cgaccctggg ccagcaggtg ttcctggggt tccgcccgga
     3541 gtcgggcctg gcgatcgcgg cgacggcgac acgccgggtg cggcggggcg ttccgttcgt
     3601 ggcgacggcg tacggactgc tgacggaaac gctctgacgc ggggcggccg ggcggccggg
     3661 cggggacgcg ggactccagg acttcggcgc accggccacc ggccaccggc caccggccac
     3721 cggctaccgg gctaccgccg aacggggcgc acggggccca acggcctacg actcaaagcc
     3781 ccacgcccac ggcatcgccc cgcgcccacg ccatcggccc acgcccccac gccccacccc
     3841 ctacggcttc ttcggcgcgg cccgctcggc gttcttcgcc gcgaccaccg cgtcgaacac
     3901 gtcccgcttc ggcagcccgg ccgcggcggc gacggccgcg atggcctcct tgcgccgctc
     3961 cccggcctcc tcgcgcaccc gcacccgtcg caccagctcc tcggcgtcca gctcctccgc
     4021 gccggagtcg gccgcgccct cgacgacgac ggtgatctcc ccgcgtacgc cgtcggccgc
     4081 ccacacggcc agctcgccca gcggaccgcg cttcacctcc tcgtacgtct tggtcagctc
     4141 ccggcagacg gcggcccggc ggtcggcgcc gaagacctcg gccatcgcgg cgagggtgtc
     4201 gtccagccgg tgcggggcct cgaagaagac catggtgcgg cgctcgtccg cgacctcgcg
     4261 cagcttgccg agccgttcgc ccgccttgcg gggcaggaac ccctcgaagc agaaccggtc
     4321 caccggcagc gcggagagcg cgagggcggt gagcaccgcg ctgggtccgg gcacggcggt
     4381 gacgcggatg tccttctcca cggcggcggc gaccagccgg tagccggggt cggacaccga
     4441 gggcatgccg gcgtccgtga cgagcaggac gcgcgcgccg ccggtcaggg cctcgacgag
     4501 ttccggcgtg cgggccgact cgttgccctc gaagtaggag acgacacgcc ccgaggtgtg
     4561 gatgccgagc gcctgggtga gccggcgcag ccgccgggtg tcctcggcgg cgacgacgtc
     4621 ggcccgctcc agttcggcgg cgaggcgggg cggggcgtcc gccacgtcgc cgatgggggt
     4681 ccctgcgagc acgagcgttc cagtcgttcc agtcacatca gccatcctcc cagcacgtgc
     4741 ggcgcccttc gcacagatgc gttccctacg atggcgcggt gacgagtacc gcacccgaag
     4801 cgcagcgcgg ccaggacgcc gggaacccgt acggcgaaca gccggccccc tggcagcggc
     4861 ggctgcgccg attcggccat gttccccggc cggagctgcc gctccgcgac cggctggacc
     4921 cgccgtacac ccggccgggg cggccgttct ggtcggtgct cggggtcggg ccggggctcg
     4981 ccgaccggct ggtgcggtgg tccgcctggg gcggtccgct gctggtggcg ctggtcgcgg
     5041 gcgtgctgcg cttctggaag ctggaccagc cgcacgccct gatattcgat gagacgtatt
     5101 acgcgaagga cgcgtgggcg ctggtcaacc aggggtacga gggcgcctgg cccaaggacg
     5161 tcgacaagct gatcctcaag aacccggacg cggtgccgat ccccaccgat ccgggctatg
     5221 tggtgcaccc gccgatgggc aagtggatca tcgggctggg cgagcagatg ttcggcttca
     5281 caccgttcgg ctggcggttc atggtcgcgg tgctcggcac ggtgtcggtg ctgctgctgt
     5341 gccggatcgg tcggcggctg ttccgctcga cgttcctggg gtgcctggcc ggcgtgctgc
     5401 tcacggtgga cgggctgcac ttcgtgatga gccggaccgc gctgctcgac ctgatcctca
     5461 tgttcttcgt gctggccgcc ttcggctgcc tgctggcgga ccgggaccag gcccgccgga
     5521 agctggccgc cgcgctgccg gtggacgcgg agggcgtgct gcgcccggac gccgggatcg
     5581 cggagagcct gcggctgggg tggcggccgt ggcggatcgc ggcgggcgtg atgctgggcc
     5641 tggccttcgc cacgaagtgg aacggcctct acgtgctggc cgcgttcggc gtgatggcgg
     5701 tgctgtggga cgtcggggcg cggcggacgg cgggggcggt acgcccgtac gcggcggtgg
     5761 cccggcggga cctggtgccg gcgttcgtct ccacggtgcc ggtcgccgtc gtcacgtacg
     5821 tcgcgtcgtg gaccggctgg atcgtcacgg acaaggggta ctaccgcgac tgggcggcga
     5881 ccgagggccg gggcggcgcg tggagcttgc tgcccgactg gctgcggagc ctgtggcact
     5941 acgagaccca ggtgtacgac ttccacgtcg gcctgacctc gggccacacc tacgagtcga
     6001 acccgtggag ctggatcgtc ctgggccggc cggtctccta cttctacgag gagcagacgg
     6061 gctgcaagga atcgtcgacc ggcaagtgcg ccagcgaggt cctcgcgatc ggcaccccgc
     6121 tgctgtggtg ggcggcgtgc gtggcactgg cgtacgtcct gtggcgctgg ttcttccgcc
     6181 gcgactggcg ggcgggggcc atcgcctgcg gcgtggcggc gggctggctg ccctggttcc
     6241 tctaccagga gcggacgatc ttcctcttct acgcggtggt gttcgtcccc ttcctctgcc
     6301 tggccgtcac gatgctgatc ggcgcgctac tgggcccggc ggccggcacg gggacccgcg
     6361 ccgaactggg cctgacgcca cccgacccga cgggcgaacg ccgccgcaca ctgggcgcga
     6421 tcgcggcggg cgtgctggtg ctgctgatca tctggaactt cgtctacttc tggccgctgt
     6481 tcacggggac gtcgatcccg gaggacctgt ggcgggaccg gatgtggctg gacacgtggg
     6541 tgtagagggg agacggcgtg cgcgtagccg ccgcccgcac tcggggcggc agcctcgacg
     6601 gggcggtctt ccccagtgac gacggagcgc ggtacgcgtc gaaggagttc gcgacggtgc
     6661 ccggccgatt cggcgtgatc cgtttgcgcg gagcggtcgg cgccagcgcg gacaacgcgg
     6721 ccctccttca cgtcgcggag gctgagcggg aagcggcggc agagccggag ggcgtgcgcg
     6781 atcacctccg gcgggaaccg gaatccccgg tactacggga cgccggcagc agccgtcgcc
     6841 gctgacagcc tccccaagac gatcaacccc gcggatcatc tcaccgacca cgatcaccaa
     6901 cctctccacg cctggtgcgg gttgtgtcca gcaggatccg gctgatgccg tcggtcatgc
     6961 ggctgtaggg gctgaggccg ctcagctcga cagcgctggt agccacgccg ctgaaggctc
     7021 gcctgatggc ccagccctcg gtcggaggga gcccgtaggt ggcgaaaaga gcctgggtgg
     7081 tgtccatggc cagctgctcg tcagcccgtt ccgccgggtg cggcgtaccg tcgtcgccat
     7141 ccactacgca gtgcagccag attcgttcga tgagttccct caacgcaagg gagtgttggc
     7201 gtaatagcgc gtggtccgcc accgccgccg tgagaacacc gtcgaagacg tcaccccacc
     7261 gcttcgcgag ggtgggcaga gagtggttgg gagcgttgtc gcagtcgacc aagagcgacg
     7321 tgatgacggt ttcgcaccgg tcgcggtcac acgcggccgt gtcggcggga aggctgcgcc
     7381 gtgccgcgcg ccgggcgagg tggttcgccc acctcccggg catgcggtgt gctgcttcga
     7441 ccggcttcca gaggggttcc caggcgtcgg agtgcaggag gtttcctggc cgcagcgtgg
     7501 tggaggccac ggcttccagc cttgcgcctg gtggccgctg cgcataggcc cgctggattg
     7561 cgccgcccgc ggccgacagg cattgcagtt gcttccgcat ctggtagcga gtggtcagca
     7621 ggtagaagag gcagtcgccc atggcgattt cggctgcctc ctcgtgtccg ctcgcaccgc
     7681 aatcgcatcg gagaacgtca tcggtaactc gtgcgagggc gtccgcgtag ccgtacacgg
     7741 catgtcctcc cctggacgcc agcgcgagga gtacctcgtt gaaggactct ccgttggcgc
     7801 agtccggcac gatgtcgacg atctcgttgt agcggatggc acagtcgatg gcgcgcttga
     7861 tcgccccaca gcggtcggcc gcggtgaagg tgcccagttc gtcggtgacg tgccggtatc
     7921 caggtgtgct catgggcagg cggtggtagg ggaccatggc ggcgtcccac cagcgtgccc
     7981 gcatgtactc cttgggtgtc accggtccgc ccgcggcgtc gacgaatccg ttcgggtccg
     8041 tgatgcgact ggtcgctgtg gtcgtgatgt cccgggccct gaggacggcg tccacgacca
     8101 ccgtgtcccg cagggcttgg gtgacggatg tccctccgag gcaagcaagt ccctcactgg
     8161 ccgctgtcgc gtaggcggcg tggccgccgc ctccggcgtc gtcccgagcg gcgacgtagt
     8221 cgacggccat catgaggcag gacgtcgaac cgcacaggtc gagcatccgg ccgtctacgc
     8281 ggataaaggc ggcggcaaac cacagcagga tgaagtcgcg catggccatc ggcacggcgt
     8341 ggaggggact tttggcatgg cgtagacagt attcgccaag gatcctgtcc acttcgccgc
     8401 ctttcctggg gactgcttct atcaggggcg ccaggctgtc cttccgcgct gtccacagcc
     8461 cggcctggat ctgtgcggat gtgacctgag ccgttgccag aagggggctc tgcatcacgc
     8521 tctggatgac ctcgggggcg aaggccgcgc tcaagatgtg acgggctgca cgctcccctg
     8581 cctcgtagcg tggaatctcc gctgaccggt agggctcgta gaccggctct tggaccatgt
     8641 acatggggag ttcatcggcg caccgcatcc ggggcgcccc atctggctca cggtgcaggg
     8701 ccgcttccat ccgagtgagg cgctcggcac atccacgacc ggctgtgagt ccgcaggcgg
     8761 cggcgtccca cccatccgtg atgcgctccc cctgagcccg caggtcgcgt acgtgcgcag
     8821 ggccggggac cgtcaccgac ggtgattccg aagacatgct gtacttcctt cctcgatgat
     8881 cgactggatg attcggtgtc agggcagtga gccttgcgtc ctcagcagac ccagtgccgg
     8941 atcggcctgc tgaaacaggc ccgcggcgtc gcgagtcgtt acgacggact cgccgtcggg
     9001 tcgtctaccg gctgcgtgcg caggttgcgg cggagttcct tgggcagcga gaaggtgatg
     9061 gactcgtcgg cggtcctgac cgtctccacg tccgtgtagc cgcgctcggc cagccacttg
     9121 aggacgctgt cgacgagcac gtcggggacc gaggcgccgg aggtcaggcc gaccgtggtg
     9181 acgccctgaa gccaggcttc gtcaatctcg tcggcgaagt ccaccaggta ggcggtgtcc
     9241 gcgccggcgc ggagggcggc ctcgaccatg cgctgggagt tcgaggagtt gcgggagccg
     9301 accacgatga ccagctgggc gtcttcggcg agcttcttga ccgcgatctg gcggttctgc
     9361 gtggcgtagc agatgtcgtc gctgggcggc gagagcaggt tggggaacct ggtcttcagc
     9421 gcgtcgaccg tttccatcgt ctcgtccacg gagagggtgg tctgggagag ccagacgacc
     9481 ttcgactcgt cacggacctc gacatgggca acgtccacgg ggccgtcgac cagcgtgatg
     9541 cggtccgggg cctcaccggt ggtgccgatg acctcctcat ggccctcgtg gccgatcagg
     9601 aggatgtcgt agtcctcgtt cgcgtaccgg atcgcttcct tgtggacctt ggtcaccagt
     9661 gggcaggtcg cgtcgatcgt ggcgagcttc cgctcggctg cctccgcgtg cacggccggg
     9721 gccacgccgt gcgccgagaa cacgacaatg gagccctcgg ggacctcctc cgtccgctcg
     9781 acgaagatca cgcccttgcg ttccagggtc tgcacgacgt acttgttgtg gacgatctcg
     9841 tggcggacat aaatcgggtc cccgtacagc tccagggcct tctcgacgac ggccacggcg
     9901 cggtccacgc cggcacacca gcctcgcggt gatgcgagca gtacccgctt cgtggccggg
     9961 gtggggcggg ccgggtgggc ctggtgcggg gtggcggtgt tcatgtggtc ctccatacgg
    10021 cctggtgggc catgtcttgg aggctggcgc ggatatcggc ggggacaggg gcagcggcca
    10081 gggcggacga tgcgcgcgcg taccgatcgc ggatcatctc ctcgaccgtg tccggggccc
    10141 cggaggcggt gatgatgctc cgtgcgatgt gtgcttgatc ttcggtgagg gtggggcatc
    10201 ccacgagcag gcgcagctga tcggcctgcg cgcggggggc gttgcgcagg gtgagtgcga
    10261 tcagacaggt gtgcttgccc tcgcgcaggt cgtccagggc cggtttcccg gtctcgaccg
    10321 gatggccgaa gaccccgagg agatcgtcgc gcagttggaa ggcttctccc aacggaacgg
    10381 cgaacgagct gagttgggcg aggagtgtgt cgggggctcc ggcgagggcg gccccgatgt
    10441 gcagggggcg ttcgatggtg tatttggcgg tcttgtaccg gatgacgcgc agggcgaggc
    10501 cgacgtcggg ggtgggttgg ctggtggcgg tcagatcgag gtactggccg tacagcacct
    10561 cgttgcgcat ggtgtcgatc aaggggagta ctcgggtgcg ttgccgcgcg tccagggctg
    10621 tctcggaggc gtgcaggagt tcgtcggacc agatgagggc gaggtcgccc atcaggatgg
    10681 cggccgcggt gccgatgtcg gtggccgcct gccgggtgcg gtccttgctg tggtgggcgg
    10741 ccagggcacg gtgcatggca ggccggccgc gccgggtcgc ggagtggtcc atcacatcgt
    10801 catggatcag gcagaaggcg tggaacatct ccagtgcggc gccgacccgt gccgcctgat
    10861 ccacaccgcc tgcgcccccc gcggcatgcc accccagcac gcagagcagc gggcggatgc
    10921 gcttgccgcc ggcgttgagg aaatctccga cgtactcggc gacttcctca gggagggcgc
    10981 cggtcctggc cgcggtgatc ttgccttcga cgaagtcgtc caggatctgc gagacgcgtt
    11041 ggcgcacctc gcctccctgg aatgcggccg aggcgtgcgc ggagtacgcg ggggcggtgt
    11101 ggaaaccggt ggaatcggtc acggctgatc acctgcttcg tcatcgcagc gggcggtgag
    11161 agcgagagct tcgtccatca atgcctcgac gatcttcgat tccggtacgg tgcgcaggac
    11221 ctggccctgt cggtagatct ggcccttgcc attgccgcag gagacgccga ggtcggcttc
    11281 gcgggattcg ccgggtccgt tgacgacgca gcccatgacg gcaatgcgca aggggtgggg
    11341 gaagccgtcg aaggccgcct cgactcggcc ggcgagtttg tggatgtcga cctggaggcg
    11401 gccgcagccg gggcaggaga cgatttcgag tctgcggggg cgcaggccga gagaggcgag
    11461 gatgtggcag ccggccttga cctgctgcac cgggtcgtcg gagagggaga cgcggatggt
    11521 gtctccgatg ccctcgccga ggaggatgcc gaaggcgacg gcggacttga tggctccttg
    11581 gaaggcgggt ccggcttcgg tgactccgag gtggaggggg tagtcgcatt gtgcggcgag
    11641 cagccggttc gcggcgatca tcgtcatggg gtcgtggtgc ttgaccgcga tcttcaggtc
    11701 cctgaagccg tgttcctgga acagggagca ctcccacagc gcggactcca cgagggcttc
    11761 gggggtggcg gagccgtgtt tggcgaggag gcgtgggtcg agggagccgg cgttgacacc
    11821 gatgcggatg ggcaccgcgg ccgccgtggc ggcttgggcg atctcgccca ccttgtcgtc
    11881 gaacttcttg atgttgccgg ggttgacgcg gacggcggcg cagccggcat cgatggcttg
    11941 gaagacgtag cggggctgga agtggatgtc ggcgatcacc gggatcgggg acttggccac
    12001 gatggcgggc aggacgtcgg cgtcgtcctg ggaggggacg gcgacgcgga tgatgtcgca
    12061 gccggcggcg gtgacttcgg cgatctgccg cagcgtggcg tcgacgtcgg cggtcgaggt
    12121 cgtggtcatg gtctgcacgg agatcggggc gccgccgccc acgggcaccg tgccgacgtt
    12181 cagttgtcgg gtcgggcggc ggcgcgccgg agtccgcgtg gtcaggggcg cggggcgcgg
    12241 ggtgggcggg ccgaggtcga tcgaggtcat cgagcgctcc tgggggtggg tgccggcgcg
    12301 tgctctgtcg ggtctgggcg caggtgggcc atggctgcgg tgaagaggcc ggtgccgtcg
    12361 agtcctgcct gggtgagcag gtgggtgcga ggcgcgtggg ggatgaaggc ggtcggcaga
    12421 ccgcaactga tcaccggggc ggcgacggcc gtatcggtac acgcctgggc cagggcggtg
    12481 ccgaagcctc cggtgcgcag tccgtcctcg accgtgacgg tcacacggtg gcgggcggcc
    12541 agggcgggca gggcggggtt gacgggcagc acccagcccg gatcggcgac cgtgaccccg
    12601 agcccctgtt cttcgagcag cacggcggcg tccagggcag ccgcggcgag cgggccggtg
    12661 gggacgagca gcacatccag ggggccgcgg tgggtgcggt gcaggatgtc caggccgtcc
    12721 atgcgggtga gcgcctcgat gtcggagccc acggtggctt tgggcagccg cagcacagtg
    12781 ggcccgccct ggacggtggt ggcctcgcgc agcatttcac gcagccgcgt ggcgtctctg
    12841 ggtgcggcga tgcgcaggcc ggggatcgtg gagaggacgg cgaggtccca catgccgtga
    12901 tgactcggtc cgtccgggcc ggtgataccg gcccggtcca gaacgaacgt gactggcagc
    12961 tggtgtaggg ccacgtccat gaggacctgg tcgaaggccc ggttcaggaa ggtggcgtag
    13021 atcgcgacga cggggtggta gccgcccatg gccagcccgg ccgcactggt gacggcgtgc
    13081 tgctcggcga ttccgacgtc gaatacccgc tccgggaagg tctgttgcat ggggagcagg
    13141 ccagtcgggc tcagcatgga ggcggtgatt gccaccacct cggggtgcgc agcggcgatc
    13201 cggcagagtt cctggccgaa gacgctggtc cacgacgggg cctcggccgt gcgggcgggg
    13261 atggggcgtc cggtggccgg gtcgacagtg cccaccgcgt gcaggcagtc cgcctcgtcc
    13321 gtctcggcgg gccggtagcc cttgcccttg accgtcatca catgcacgac cgccggccgg
    13381 gacagggcgc gggcccgtcg taacacttgg tcgatctccc cggtgtggtg tccgtcgacg
    13441 ggcccgaagt aggtgaagcc gaggtcggtg aacaggttgc ggcacgcttc cgcgccgccg
    13501 gatttcagca cgttcaggtg ctcggcgagg gctccggtgg taggggcgta ggagcggccg
    13561 ttgtcgttga ggacgatgat gacgggccgg tccttcgcgg cgccgaggtt gttcagcgct
    13621 tcccacgcca ggccgccggt catcgcgccg tcgccgatga ccgccaccac cgcacggtca
    13681 ctctcaccgg cgagctggcg ggccttggcc agaccgtccg cgtacgacag cgcggtggaa
    13741 gcgtgcgagt tctccaccag atcgtgcacc gactccgaac gggagggata ccccgtcagc
    13801 cctccggcct gccgcagcga gtcgaacgcc tcacggcggc cggtcagcaa tttgtgcaca
    13861 tacgcctgat gaccgatgtc gaacaccagc gcatcccgcg gagactcgaa tacccggtgc
    13921 agggcgagcg tcagctccac catccccaga ttcggaccca gatgcccgcc cgacgcacac
    13981 accttctcga ccaggaactc cctgatctcc gccgccagca ccggtaactg ctcagcagcc
    14041 agagcccgca gcgctcctcc cgcttcggcc gtcgttcccg acagaagact ggttcgcatc
    14101 gtcatgggag gtgcccacat cctcaagagg tcagggaaga gacagcccgg gaggccggtg
    14161 atcttccgga ttcagacgga gtgcggctct gaagaccgcc ggaccgtagc cagccgcgga
    14221 gaccagccac gacacaacgg gcccacctcc agtgaggcag acccggtgcc gcgacgggac
    14281 ccgggggaga agaccgatcc gtgcacgcgt tgaacgcttg tgaggacgtt cacaaacgac
    14341 ggtcgtcatc cggctttacc aagcgcccgg aaccacgccc tgcccccggc cgccccgagc
    14401 cacgtccttc tgtctcacgg gtgggaaacc cgctgccgcg gcgcctcggc cgcgccggcc
    14461 gacaacgccc gcctcagcca cgtcctccat cgcgtatgac gcactcgctg cccgagccca
    14521 cctcgactga ccggcgattg tcgccgtccc gcagacacaa ggcaccctcc ggggccgttg
    14581 cgcggaccgc cgtcccatcc ggtacatctg ccggagtccg tgtcgttccc cgggcggggg
    14641 cgggggcggt tacggacctg gccggtccgt tggacgggcg gcgggctgat ggtctgtggg
    14701 ggcgtgtgtt cattcgaccc ggcgacgatc ttgtcccacc tgggcgcggg cgaagaagcc
    14761 ggtgtcggtc ggtccgggca tcagggcggt catcggccca cctgggtcct ccagttcgtt
    14821 ctggcgaacg gcggcgagcc aggcccatga gatgccggcc caggccgaag tgagggagcc
    14881 tcacaccgca ggcgggtccg cggcttcacc ctgtccactc ctcgccctca cggaaggaag
    14941 ctcgacagag agcgcttaca agtggcgtgt tccggtcctg taacaagcgc ctcaagtccc
    15001 ggccgcacgc cctagtcttg atggcagtga tgccttgaac gcgttcaagg gactctcctg
    15061 gggaggcgga caacaggaat gcgcagtgga gcgaaggtcg tcgtcatcgg cggcgtgttc
    15121 gtcctcgtgg ccggcggact cggatacggg gcgtacgccg tgcttggggg cgagggcggg
    15181 gggttcgcct ccgccccggt gaagacgggg ccgcccagtg ccgccgagac agcggatgcc
    15241 tcggcggcct tcttcaaggc gtgggcggcc ggggacgcgg ccggtgcggc gcggctcacc
    15301 gacaacgaga ccgcagccga accggtcctc acctcgtacg gcaagaccgc tcacatcggc
    15361 aaggtgagga taacccccgg cgcggcggtc ggcgcgaagg ttccctacac cgtcgaggcc
    15421 accgtctcgt accggggcaa gtcccaaccc ctcgcgtacg agtccgagtt gagcatcgtg
    15481 cgcggtcgca cgaccggcaa ggccctcgtc gactgggtgc ccggcgtcgt gcacccccgg
    15541 ctgtccgagg gggccacgct gcgcacgggc gaggccgagt cgccgcagat cgaggccgtc
    15601 gaccgcgacg gcgtggtgct caccaaggag aagtacccgt cgctcggccc gatcctggac
    15661 agcctgcgcc agaagtacgg cgccacggcc ggcggtacgc ccggtatcga gacctgggtc
    15721 gagcccgccg acgaaaagcg gcccggcacc accctgttga ccctcgccaa gggcaagccc
    15781 ggcacggtgc agacgacgct ggacgcgggt gcccaggccg ccgccgagcg ggcggtgcgg
    15841 aagtaccagc aggcgtcggt cgtcgcggtg cagccctcca ccggcgcgat ccaggcggtc
    15901 gccaacaacc ccgcgaccgg cttcaacgcc gccatgcagg gccagcaggc gcccggctcc
    15961 acgatgaaga tcgtgaccgc cgcgctgctt ctggagaagg ggctcgtcac ggcgaacggg
    16021 gcggcggagt gcccgaagga agtcgtgtac cagggcgcga agttccacaa cctggaccgc
    16081 ttcgacctgc cggacggcag cacgttcacg cagagcttcg cccggtcgtg caacaccgcc
    16141 ttcatcaagc tgatagacga cgtgaaggac gactccgcgc tcgccaagga ggcccgggac
    16201 gtcttcgggc tcggcctgga ctggaagacc ggcgtcgtct ccaccgacgg cagcgtgccg
    16261 gaggaggcgg gcggcgtggc cgcggcccag tacatcggtc agggcacggt ccagatgaac
    16321 gccctcaaca tggcgtccgt caccgcgacc gcccgcaccg gtacgttccg tcagcccgtg
    16381 ctcgtcccgc agtccctgga cgaccggaag ctggccgtca ccgaacgctc gctgtcgccg
    16441 tcggccagac ggcagctcac cacgatgatg cgggccacgg ccgcctgggg cacgggtgcc
    16501 aaggcgatgg cctcggtggg cggcgacaag ggggccaaga ccggttcggc ggaggtcgac
    16561 gggcaagcca cgtcgaacag ttggttcacc gggttcagcg acgacctcgc cgcggcggcg
    16621 gtcgtccaga ccggcggcca cggcggcgac gcggcgggcc cgatcgtcgc cgaggtcctg
    16681 cgcgcgggca gctgaatcgg gatcgcgcag gctcgtgagg gggaccccgg ggtgagggaa
    16741 gctcccgggg cgagggcaga agctgacctg gggcgggggc acaagcaccc ccgccccagg
    16801 tcatcggcat ccccgcccca ggtcacgcgg gtcagccgcc tgctctcacg ccctggcccg
    16861 tgcccgtctc cggctacgcc gagagcttga tcgagttgat cggggtcagg tccacgtccc
    16921 agtaggtcca ggtgggcatc ttcgcgccgc agcccactcc gttgtacccc gtgcacagct
    16981 gcacggacgc cccgccggtc tgattgttga acacccggtg ggtgcccgtc tggttgctga
    17041 ggttgtagac gccgtactgg tagtacgtcg cttcgggccg gttgccgttc caggacgcgc
    17101 ccgggtagat gcagacgtac cccgactggc atccggcgta ggcgtcctgg gcgtccctgg
    17161 tgtcgggagc gccggcctgg gcccccgctc ccgtcgccag cacggctccg gccgtgaacg
    17221 tgagcgccac tgccgctcgt acgagattgc gcatgtcgtt cctccctgcg tcgggcccct
    17281 ggacccggcg ctcccctgtg ggatggttgg ttccggtcgt ccggtcgtcc gttccgcgtc
    17341 gttcccttcg cggcccggcc gtccggatgg aagaagcgtg gcagggaccc gctccgcgcg
    17401 ccgcaccctt tcatcagggt gaaaccgtcg ccggttcggg cctcggcagc catgcgtcca
    17461 cggcccctcc cggcaatcgg cccccggtcg tcgtctccag cagtcgccgc ccgagcggcg
    17521 acggctggtg cagcacgtac cgtccttcct tccggccggc ggcgaggccc gcctcccgca
    17581 ggatcgccag ctgctggctg gtgttgggca gcgagcagcc caccgcgtcc gccagctcgg
    17641 aggtcgtggc gcagccgcgt acggccatct cgtacaggag cgcggcacgc gtcgggccca
    17701 gcagccgggc cagcgaggtg acggcggcgg agccgcccgg gacggccggc gggtggatcg
    17761 gcttcgcgac cgggtagacc agcaccggca gcaacgcctc gtcgaccagg gtgatcggct
    17821 tgcgccagca gaagtacgac ggcaccagca gcaggccgcg ccccgccagg tgcatgtccc
    17881 gctcgaccgg gtacgtcact tccagcacgg gcgggctcca ccgggccatc gggcggaagg
    17941 tctccaacag cgcccgggtg ccgcccgccg cgagtcggcg cgagcgccag gcgacgtcgg
    18001 aggccaccgc cgcgtcgatc cacggccggt acggggcgac gaacgccgcg tcgtacgcgg
    18061 tgagcaggcc gccgagcgcc cggagcgccg ccgcgtcgcc cacggcgagc tgctccgccg
    18121 cgaacggccg catccgtggc tcggactgcg cgagcagcgt gatctcgtgg cgcaggcggc
    18181 tccgaggtgt cgacagcacc cggtccacgc cctggcgcag gtcgacgttg ccgccgtcca
    18241 cggcgggggt caggaagtcg gggatgtacg ggccgaacgg caccaggctg cgcagcgcga
    18301 gcgcgatcgc ccggtccgtc ccgccaccgg ccccccgaag ctggggcgcc acggcgcgcc
    18361 gccacggccc gaacgcgatc cggccctcgt cggtctggag ccggcagacg ctcgacagga
    18421 tctcccagag cggatcgggg cgcggcgcga tgcggacgta ctccagatcc tgggcggtga
    18481 agtggatgcg caacactatt tcccccttgt cgccctttcc cctctatgcc gccctatcac
    18541 tgtggcgcgg gaaggggaag gcgcgatcag aacacaccct ttccggccag ggattggccg
    18601 gatgacctgg cgaaagggcg cgggagcgcg cgatgagggt cgcggggctc ccttccggaa
    18661 cgtcgcgcgt gccccctgcg ccacctacgg ctgaggtgcg gccgtgagcg ccgcactcgt
    18721 ggaccgcacg tgcggggggc ttctgatgcc tccacagctg aacacgcgat cacccgagcg
    18781 aagccagggc ggatgccacg agagaacgtg cggcggctcc ccgcaccgat tcctgggaga
    18841 ggcggccaaa ggctcgcctg tacagatcca cttggcttgg ctgtacgagg gtggatgcgg
    18901 cgtccaaagt atccgcgtgc accctggcat cgtcgaacat cgtgaacgtc ggcatggacc
    18961 acatggtccg tcgcgctgag aacggcacga ttcccacggc cacgttctgg agattcatga
    19021 cccccaagag gtggcccagc tgcgcggcca tggtctcgac cgtgcacagc cgatggcgca
    19081 ggaccgattc ctccagaacg aacgagaacc ggtgtgcgcc gttggtcagc accgcgttgc
    19141 gcctcatgcg gacctcgacg gcatcggtca cgtcatcggg tgtgcctcgg aactccgcga
    19201 tggacgacag aagcgcggtg gcgtacccgg gcgtctggag gaagccgggg atcacgtcgg
    19261 agacgtagac ccggaacaca cgagttcgct ggtacaggct ctcggtggac tcctgcacac
    19321 gacggaggcc ggttcgctgg agtcgtctcc actggacgtg ggcgtccgcg gattgcctgc
    19381 ttgccgcgat caggtccggc gccctgtcgg cggcatcgca ggctcggcac cacgcctgga
    19441 tgtccgcgtc ggacggtggc gtcctggcgt ttccgatacg cgacgccttc gcatccgacc
    19501 agccgcacct gacggccagc tcccgcccgc tgattccggc gtccctgcgg agatcgcgca
    19561 gccggcccgc cagttcttct cgggcttgct gaacgctcga cgaggggtgc gagggcgtgg
    19621 agccggcttt cgtcagatcg cgtacaggcg gtgcggaact gctctctccc agactgcttc
    19681 gaaggccgac gagcagagtt tcacggtctc cgcgtccgag gtgatctcat cctcgaccac
    19741 tgcgccgtcc cctgagaagt ggtgcactcg caggagcgcg ccgtcgaaga gccagaagtc
    19801 gtttcccggg aggggaatgt ccgtggccag tcgccttggt agccagcgga cctcttctcc
    19861 cgccgtgacg ttcgcgtgcg tcacgtagtg ctcccagcga atgtactgcg tcacccggac
    19921 agtggtcccg gtcggtgttc gggtcgatgc cgacgaactc cacggccatg gctcgctccc
    19981 tgatctaagg gcgtccgcca gtaggtcatc ggatgcgtga gtttcgaggg cgggtgttcc
    20041 agcggtagag ggtccaggcg cgtcggatca ggcagcggac cgtgatgacg gtgcagggat
    20101 ccggccaatg gcttcgggtc aggtccgctt gcggctcgcg atctcctcgg agagccgctg
    20161 cacgtggacg gggtccgcgt cccgggcaag ggcgacgtag tggtccctga cggccggccg
    20221 gtagcgcacg ggcaacgtct gtcctggggc gagtcgggtg agctcggtga tcgtgaggtc
    20281 ttcgtctgcg ataccgcgga acgagcggcc gccgacggtc tccacgtcga acatcaagac
    20341 cacgcgcggg ttgctgttga cctcccgcca gtcgacgaga atgccgagcg caagcgcccc
    20401 cgtacgcagt tccgcattgc gctgccgtgc atcactgctc aggaacgggt tcggggcgac
    20461 gcccgggaaa tcgggcccga caccgagcga ttcccgactc aggtcgggcc tgagctgcgc
    20521 catcacatcg ttgagcttct tctgcgaact gaacatgttg atggtgagct tcttcttcga
    20581 accgaacatc ctgacccctc cctcacgccg gtgccggaat ctcggccggg tgcttcgcac
    20641 tccgcgcgat tgtacgagcg tccggcagta ggtgctggca gcagggcaag cacggttcac
    20701 ccgatcatgg agttctctac gcttcatgat caccgaggga tccgtgcctg ccgtcccatc
    20761 atgcattctc gacccgatcc gcgaccagtt cctcgcgctc ctgcccgtgc gcgaggaccg
    20821 gcacccgctg ggctgtcaca acccccggat cagcgacgcc gtcgtattcg accggctggt
    20881 gcgggtcctg gtcttcggct gcggatacga acgcgccgcc gacgaacact gctcggccac
    20941 caccttgcgc cgacgccgcg acgagtggat ctccgaaggc gtgatggaga gcctgcggct
    21001 gctcgcgctc gccgcctacg accgcatgat cggcctcgaa ctcgaccacc tgagcgccga
    21061 cggctgcatc accaaggcgc cctccggcgg tgaatgcgcc gggaagagcc cggtcgaccg
    21121 tg
//
