LOCUS       NZ_ML123034            41014 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1232239
            Orig. end                         :: 1273253
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..41014
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="PKS-like"
                     /product="ectoine"
                     /region_number="8"
                     /rules="(t2pks2 or ksIII)"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..41014
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="ectoine_synt"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="ectoine"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..41014
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21014](+)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21014
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     cand_cluster    857..11255
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    857..11255
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5856:6255](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      5857..6255
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="2"
     misc_feature    complement(1011..1024)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.68"
                     /tool="antismash"
     gene            complement(1151..2251)
                     /locus_tag="EES43_RS05405"
                     /old_locus_tag="EES43_05390"
     CDS             complement(1151..2251)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123619.1"
                     /locus_tag="EES43_RS05405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05390"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_206429993.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.9e-19, bitscore:
                     67.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQEGQRVLRVKGRVLIGPDEVRDELWAVDGRIVHERPPGADDA
                     VTVTGWALPGLVDAHCHVGLDRHGPVDAATAEKQALTDREAGTLLIRDAGSPSDTRWID
                     DRADLPKIIRAGRHIARTRRYIRHYAHEIEPGDLVAYVAREARRGDGWVKLVGDWIDRD
                     AGDLTACWPRGEVEAAIAEAHRLGARVTAHCFAEDALRDLVEAGIDCVEHATGLTEDTI
                     PLFAERGVAIVPTLVNIATFPDLAAGGEAKFPRWSAHMRELYERRYDTVRAAYDAGIPV
                     FVGTDAGGSLAHGLVAGEVAELVKAGIPPLEALSATAWGARRWLGRPVLEEGAPADLVV
                     YDEDPRADVRVLAAPRHVVLNGRIVG"
     misc_feature    2299..2312
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            2352..3458
                     /locus_tag="EES43_RS05410"
                     /old_locus_tag="EES43_05395"
     CDS             2352..3458
                     /NRPS_PKS="Domain: Aminotran_5 (73-271). E-value: 2.3e-28.
                     Score: 91.1. Matches aSDomain:
                     nrpspksdomains_EES43_RS05410_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104676.1"
                     /locus_tag="EES43_RS05410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05395"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_124267634.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1e-21, bitscore:
                     75.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLPPLTAAHFAAIERRVASLLATEQDVVVMQGEALLPLE
                     GCIRGGARPGSTALNVVTGPYGQTFGDWLRDCGAEVVDLTVPFHAAVTAEQVAEALAER
                     PEIDFVSLVHAEAATGNTNPVAEIGEAVRAHGALFMLDAVASVGAEPLLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSERAWERFAANPAAPRRSYLSLLDWKERWIDAGRTALPHAP
                     AQLEMLALEACVERIENEGPAAVMARHTAAAAATRAGAVALGGGLEPYVHEARDAAPVA
                     TTLRAPAGVDATALVAHARAAQPSLPLIAGGGALSKEMIRVNHYGADATRGAVLSSLAA
                     LGAALADAGRQVDLEAARKAVGETWPSA"
     aSDomain        2571..3164
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05410_Aminotran_5.1"
                     /evalue="2.30E-28"
                     /label="EES43_RS05410_Aminotran_5.1"
                     /locus_tag="EES43_RS05410"
                     /protein_end="271"
                     /protein_start="73"
                     /score="91.1"
                     /tool="antismash"
                     /translation="LRDCGAEVVDLTVPFHAAVTAEQVAEALAERPEIDFVSLVHAEAA
                     TGNTNPVAEIGEAVRAHGALFMLDAVASVGAEPLLPDAWGVDLCVIGAQKAMGGPAGVS
                     AVSVSERAWERFAANPAAPRRSYLSLLDWKERWIDAGRTALPHAPAQLEMLALEACVER
                     IENEGPAAVMARHTAAAAATRAGAVALGGGLEPYV"
     misc_feature    3623..3640
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.5"
                     /tool="antismash"
     misc_feature    complement(3625..3640)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    3635..3650
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    3769..3781
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     misc_feature    complement(3781..3795)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     gene            3806..4336
                     /gene="ectA"
                     /locus_tag="EES43_RS05415"
                     /old_locus_tag="EES43_05400"
     CDS             3806..4336
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123622.1"
                     /locus_tag="EES43_RS05415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05400"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_124267635.1"
                     /transl_table=11
                     /translation="MTAAPADVARARSEFLSIDTPRVEDGAAIWRIARDSEVLDLNSSY
                     SYLLWCRDFAATSVVARDETGEPIAFVTGYIRPDRPETLVVWQVAVDREHRGRGLAATL
                     LDALTARVAADQGLAAVETTITPDNTASDRLFTSYARRHDVPLEQEVLFDGELFPEGTH
                     LPEVLYRIGPFTS"
     gene            4509..5771
                     /gene="ectB"
                     /locus_tag="EES43_RS05420"
                     /old_locus_tag="EES43_05405"
     CDS             4509..5771
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-363). E-value: 4.8e-71.
                     Score: 231.4. Matches aSDomain:
                     nrpspksdomains_EES43_RS05420_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="EES43_RS05420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05405"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_124267636.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.9e-76, bitscore:
                     255.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITPPALSVFETLESEVRSYCRGWPAVFDRAQGARLTDEDGHSY
                     LDFFAGAGSLNYGHNNPVLKRALIDYIERDGITHGLDMATTAKRAFLETFQNVILRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGRESVVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGQVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARA
                     EWLRALQDLCHRQDMLLIVDDIQMGCGRTGGFFSFEEAGIVPDIVTLSKSISGYGLPMS
                     LCLFKPELDIWEPGEHNGTFRGNNPAFVTAAAALDAYWADGQMEKQTLARGEQIEQALL
                     AVCAEEPTAHFRGRGLVWGMEFEDPTRASAVCAKAFELGLLLETSGPQSEVVKLLPPLT
                     ITPEELDEGLRTLARCVRETA"
     aSDomain        4593..5597
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05420_Aminotran_3.1"
                     /evalue="4.80E-71"
                     /label="EES43_RS05420_Aminotran_3.1"
                     /locus_tag="EES43_RS05420"
                     /protein_end="363"
                     /protein_start="28"
                     /score="231.4"
                     /tool="antismash"
                     /translation="FDRAQGARLTDEDGHSYLDFFAGAGSLNYGHNNPVLKRALIDYIE
                     RDGITHGLDMATTAKRAFLETFQNVILRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     RESVVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGQVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARAEWLRALQDLCHRQDMLLIVDDIQMGCGR
                     TGGFFSFEEAGIVPDIVTLSKSISGYGLPMSLCLFKPELDIWEPGEHNGTFRGNNPAFV
                     TAAAALDAYWADGQMEKQTLARGEQIEQALLAVCAEEPTAHFRGRGLVWGMEFE"
     gene            5857..6255
                     /locus_tag="EES43_RS05425"
                     /old_locus_tag="EES43_05410"
     CDS             5857..6255
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="EES43_RS05425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05410"
                     /product="ectoine synthase"
                     /protein_id="WP_124267637.1"
                     /sec_met_domain="ectoine_synt (E-value: 2.2e-53, bitscore:
                     177.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFSDIENTDRHVKAASGTWESKRIVLAKEKVGFSLHETVLY
                     AGTETSMWYANHIEAVLCTEGEAELTNDETGETHWISPGTMYLLDGHEHHTLRPKTDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEEG"
     gene            6258..7151
                     /gene="thpD"
                     /locus_tag="EES43_RS05430"
                     /old_locus_tag="EES43_05415"
     CDS             6258..7151
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156966.1"
                     /locus_tag="EES43_RS05430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05415"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_124267638.1"
                     /sec_met_domain="PhyH (E-value: 7.1e-37, bitscore: 126.2,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEVRADLYPSRGAAEMTTPRQDPVIWSAPGAPGPIAAKDLQGY
                     EHDGFLTVDQLITPDEVAVYEAELNRLVSDPAVRADDRSIIEPTSQSVRSVFEVHRISE
                     VFAALVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGLPNM
                     RTVSVSIALTENFDTNGGLMIMPGSHKSFLGCAGETPKDNYKKSLQMQDAGTPSDEALT
                     KMADRHGIRLFTGRAGSATWFDCNAMHGSGDNITPYARSNVFIVFNSVENEAQEPFAAP
                     IRRPEFIGARDFTPVR"
     gene            complement(7362..8417)
                     /locus_tag="EES43_RS05435"
                     /old_locus_tag="EES43_05420"
     CDS             complement(7362..8417)
                     /NRPS_PKS="Domain: Aminotran_5 (19-346). E-value: 2.7e-23.
                     Score: 74.4. Matches aSDomain:
                     nrpspksdomains_EES43_RS05435_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518880.1"
                     /locus_tag="EES43_RS05435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05420"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_124267639.1"
                     /sec_met_domain="Aminotran_5 (E-value: 3.4e-18, bitscore:
                     64.2, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8e-05, bitscore:
                     20.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITALSQAATAEFAPETTYLDTSTWGLLPRRTIAAVKALADENA
                     AGLRVGAGSLDAVESARTGFARLVGVHPDRVATGGSVAVHVGLIAASLPPEAEVLCPEG
                     EFSSLVSPFAHRSDLRLRYVPLAGLAGAVRPDTALVAFSAVQSADGRTADLAAVRAAAA
                     AHGARTLVDATQAAGWFPLEAGEYDYTVTGGFKYLLCPRGTSFLTVTEEAQAHLPALFA
                     GWISSGAPWNAMYGPAELAPTARRFDEPPAFLSYHGAERSLALLGEVGVDALHAHATSL
                     AARLRAGLAVLGHEAVPGESAIVAVPGLGHRKEDLARAGIRVSDRAGNLRASFHLYNTE
                     AHVDRLLDVLA"
     aSDomain        complement(7380..8360)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05435_Aminotran_5.1"
                     /evalue="2.70E-23"
                     /label="EES43_RS05435_Aminotran_5.1"
                     /locus_tag="EES43_RS05435"
                     /protein_end="346"
                     /protein_start="19"
                     /score="74.4"
                     /tool="antismash"
                     /translation="YLDTSTWGLLPRRTIAAVKALADENAAGLRVGAGSLDAVESARTG
                     FARLVGVHPDRVATGGSVAVHVGLIAASLPPEAEVLCPEGEFSSLVSPFAHRSDLRLRY
                     VPLAGLAGAVRPDTALVAFSAVQSADGRTADLAAVRAAAAAHGARTLVDATQAAGWFPL
                     EAGEYDYTVTGGFKYLLCPRGTSFLTVTEEAQAHLPALFAGWISSGAPWNAMYGPAELA
                     PTARRFDEPPAFLSYHGAERSLALLGEVGVDALHAHATSLAARLRAGLAVLGHEAVPGE
                     SAIVAVPGLGHRKEDLARAGIRVSDRAGNLRASFHLYNTEAHVDRL"
     gene            complement(8512..9231)
                     /locus_tag="EES43_RS05440"
                     /old_locus_tag="EES43_05425"
     CDS             complement(8512..9231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005319054.1"
                     /locus_tag="EES43_RS05440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05425"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_124267640.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYIGKARFEKGLARFAHRDEVEVVHRSFELDP
                     GRAKGDRALVVDMLAAKYGRTREEAASMEANVADNARAEGLGYRVEGRDHGSTFDIHRL
                     LHLAKARGRQDELLTLAYRANFAEERSVFDDEVLVALAVEAGLDAGEARAVLADSEAYA
                     DDVRADEREASELGANAVPFFVLDRRYGISGGQPSEVFVQALEQAWKDHRATALTPVGG
                     DAAACDADGACEVPRAD"
     gene            9829..10698
                     /locus_tag="EES43_RS05445"
                     /old_locus_tag="EES43_05430"
     CDS             9829..10698
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349972.1"
                     /locus_tag="EES43_RS05445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05430"
                     /product="phosphotransferase"
                     /protein_id="WP_124267641.1"
                     /sec_met_domain="APH (E-value: 4.8e-06, bitscore: 25.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLERVRWEELPAELRDAIETKAGEVTESEVVAEGLNCSTALMIRT
                     EKHGSLFLKGVRENVTVEVGALRQEERVNGALGGISAQLRHRFRLAGWYCLTFEYVDNG
                     RHADMTPGSSDLDAIGFALDRMQQLVFPNLLPYGRFQFTVPTLADRFEDFINTAESRAL
                     QGDNLLHTDINPYNILMYGAHNSRACVVDWAMPATGPAWVDPAYTAVRLMECGHTPAAA
                     LKWLGGFTSWQYADPESVRALVNAVCRQWTARVGEKDARYSNGNYEHLLGYPHKTGKRP
                     TSRKRPPG"
     gene            complement(10723..11862)
                     /locus_tag="EES43_RS05450"
                     /old_locus_tag="EES43_05435"
     CDS             complement(10723..11862)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024260.4"
                     /locus_tag="EES43_RS05450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05435"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_124267642.1"
                     /transl_table=11
                     /translation="MGAPPYLVSTVPDPLTDTLGLTGARCVLVRGLTAGGSWALRFPAP
                     GRLKVHAVLRGASRLMVDGGERPVLLEQGDVVAFGGGLSYVLAADPSVPPQDAPALLRA
                     SPHLFAHAGEEGVTEVVSVGAHFELNTAGEDLLLQALPPVIHLSRTGEEAPALCWLLEQ
                     VLREMSADRPGANGVAEYLSQLVFAHVLRACLARSDAYPAGWLRALADERIAPALRLMH
                     ADPARPWHVTELARAAAMSRSVFAGVFTSVAGVPPLTYLHQWRIRLAEKTLIQKDTPVS
                     ELALSLGYASESTFSHAFKRATGIPPKRFRDAARGSRDRSEAERAVTAAWRGASRPDGD
                     EPGIDERRLAEAGAEEGPGSAETRPGRGGSGPPVRSRES"
     misc_feature    12019..12037
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            12317..13786
                     /locus_tag="EES43_RS05455"
                     /old_locus_tag="EES43_05440"
     CDS             12317..13786
                     /NRPS_PKS="Domain: PKS_AT (10-283). E-value: 4.5e-49.
                     Score: 159.3. Matches aSDomain:
                     nrpspksdomains_EES43_RS05455_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (410-477). E-value: 2.4e-08.
                     Score: 26.2. Matches aSDomain:
                     nrpspksdomains_EES43_RS05455_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="EES43_RS05455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05440"
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_164493117.1"
                     /sec_met_domain="PKS_AT (E-value: 4.5e-47, bitscore: 159.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.3e-06, bitscore:
                     25.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGTVAAPRGGVLRDFHNRYESVRESLSLIDTAAREMGLPDISSR
                     LIEHDGTTDRRGPEVQYLEIFAVSIATHHVLIAEGVRPVAIVGQSIGELWALAAAGRLS
                     VDDAARLAVARSRALTRQNWGGKMLAVGVDGRRAESLAGLINHPDLVLACENTPRQSVI
                     SGPEPLIEQVERVADALGWPSFRLDVPHPTHTPAMAQASRDLRATAPRVAYGAGRWRVC
                     SPWLGRDVGDDDPVGLVADALTARVRILRTIRDLHAAGADVFVECGEWPVVTKFVEASV
                     PGVRCVVPLSGSDPVAAVRELVTGSTDGGPFLPRPPAPSGTERGPAVRVSAATASAPVP
                     ALLTAAPLSGTTNVSASAPSMSYVATRPAPAPATPAAPEAPAAPASTPVAPVAPVAPPA
                     SAEWDYETVLAELRTLYGDFLGYPPDLLGEDDGLESELGVESLKQVALLGRVSERFGLP
                     GLRANSSLLTVGTLRRIAESVVQGRAEAAAR"
     aSDomain        12347..13165
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05455_PKS_AT.1"
                     /evalue="4.50E-49"
                     /label="EES43_RS05455_PKS_AT.1"
                     /locus_tag="EES43_RS05455"
                     /protein_end="283"
                     /protein_start="10"
                     /score="159.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: (unknown)"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="GVLRDFHNRYESVRESLSLIDTAAREMGLPDISSRLIEHDGTTDR
                     RGPEVQYLEIFAVSIATHHVLIAEGVRPVAIVGQSIGELWALAAAGRLSVDDAARLAVA
                     RSRALTRQNWGGKMLAVGVDGRRAESLAGLINHPDLVLACENTPRQSVISGPEPLIEQV
                     ERVADALGWPSFRLDVPHPTHTPAMAQASRDLRATAPRVAYGAGRWRVCSPWLGRDVGD
                     DDPVGLVADALTARVRILRTIRDLHAAGADVFVECGEWPVVTKFVEASVPG"
     aSModule        12347..13747
                     /complete
                     /domains="nrpspksdomains_EES43_RS05455_PKS_AT.1"
                     /domains="nrpspksdomains_EES43_RS05455_PP-binding.1"
                     /locus_tags="EES43_RS05455"
                     /monomer_pairings="mal -> mal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       12554..12670
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EES43_RS05455_0001"
                     /evalue="1.30E-11"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="EES43_RS05455"
                     /protein_end="118"
                     /protein_start="79"
                     /score="36.5"
                     /tool="antismash"
                     /translation="GVRPVAIVGQSIGELWALAAAGRLSVDDAARLAVARSRA"
     aSDomain        13547..13747
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05455_PP-binding.1"
                     /evalue="2.40E-08"
                     /label="EES43_RS05455_PP-binding.1"
                     /locus_tag="EES43_RS05455"
                     /protein_end="477"
                     /protein_start="410"
                     /score="26.2"
                     /tool="antismash"
                     /translation="ELRTLYGDFLGYPPDLLGEDDGLESELGVESLKQVALLGRVSERF
                     GLPGLRANSSLLTVGTLRRIAE"
     gene            13783..19983
                     /locus_tag="EES43_RS05460"
                     /old_locus_tag="EES43_05445"
     CDS             13783..19983
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (552-1036). E-value:
                     1.2e-72. Score: 237.1. Matches aSDomain:
                     nrpspksdomains_EES43_RS05460_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KR (1446-1668). E-value: 7.8e-24.
                     Score: 76.5. Matches aSDomain:
                     nrpspksdomains_EES43_RS05460_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_KS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="EES43_RS05460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05445"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_124267644.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.4e-05,
                     bitscore: 20.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.6e-34, bitscore:
                     118.4, seeds: 47, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.1e-29, bitscore:
                     102.2, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.2e-70, bitscore: 237.1,
                     seeds: 2284, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTDHLRGRVALVTGAAKSLGADIVRRLAEGGAHVIVNYFHSVE
                     QAESLRAELEQAGHSCEFIRASVAKTSEIDRMFDLVRERHGRLDILINNAAGGAFLPLF
                     GVDDTYWQRAWSTNVMAAYHCSRRAAELMAGREGASILCLSSVGAHQPVPGYGPGGVTK
                     AALESLVRYLALELVGRGIRVNTVLLGSVASEIVVNLDAPDAALGDPAGTSELMRRTLS
                     TPEAARLIVHLLHEDAGFITGQTIFADGGISIGGMQGMRLHSRLADQVSRTPRTSTTGT
                     STPVGSTPAPGQPAAVRPAPAPAPAPAPAPAPAPAPAASPQPDRTPKPEPEHEPEPEPE
                     PEPDRWRSRKPETEAEADPGAVAVVGLGLTLPGANNTAEFWDRLREGVLLSSEPSAFEL
                     KHFWAPTREETDAFYVREAGYLHDFVPDPASVAEPDGNVGHPGWPRTTRWLRHCAVQAL
                     AGVGRAPKDRYLAVTTGIHDQTGLGAQGVVLGDEYRRMVRGAIPADRDGDWLAELADHA
                     ISAHYGGDGGNPQGYLPASVSRDALRGLVPDDSQHLTLDSACASGLFAVDAAVKALREG
                     SCDVALAGGTAVVEPIGFTLFCRAQGISMSGRVRPFDRAADGTLIGEGAVMLVLKSYAR
                     AVADGDRVLGVIRGTGLAADGRGKGIHAPAPRGQELAIARAWADAGVEADDVDWIVAHG
                     TGTPVGDEIELRSLLSRLGPRRKACLLTSNKQVFGHTGVLAGLVSVAHALVALERRAVP
                     GQPVVTDPHPLLGDGSRLTVPVEDRPWPADGTRPRVVGVSSFGLGGADAHVVLSDRVPP
                     AAPAGRRGGAATADAEDLVVVGWNAHLPGLASDRVPAWLSGDGPRPEAGFGTPYPLPSP
                     RDVRIPPLTMRHMDAAHLMMLQVLGPLLEQLGEPGAGLRPTTAIVVGSTLPTTHNTRAA
                     LRVHARECATAFDILPDPKQAQALKTYLAKGMEDAREVIPGDLNEDDFTGAVSCILSGR
                     AANYYDFQALGTSVYSHRDSAHTAVDLALRQLRHRACDLALVGAVCLRPISGWDRHLTG
                     LVPEGRSIAEGAAVLAVTRLSTALEHGLPVLGALSTAVGGSGPEESATPAHSLPALADA
                     GHTYLSLDALLTVVRAVVTGTDALVTPAAAGSPLIRFTPAAEPPRPGPARQAPEQVAAP
                     EQAAPEQARPEHTAADRAAGPEQAAAPEQAAPEQAAAPEQAAPEDRSAPEHDEGFTGRR
                     QTFRLVPTTPPSRNPAAPALPPGTVVITDAPDLAAAVAGPDIALWSPRPGVAGTTHVPP
                     EEAPGALAGLPFVPRHIRVLSRLPDLHAGGHGGDEAEAARVEDLQDLTFTALQAALPAL
                     RSGGSLSAVLLGPVPDDLPPPLSALFTGLVRSVRAEVPQCGGVTLLSDAPDAARALDQL
                     ARAGTAQVPAHTLACRGGDWFALAVADDPAPPPPAGAASLPPGAVVVAFGGARGITPEL
                     LHAVARTSDRPHVYVIGRTPLPESGEPLPPQAEFIAAGRRARPGASVRELRADYEKAQA
                     RLEVRRTVHRLTELCGPDRVHHRVCDVLDAERTTAVLGEVLDRHGRIDLLINTVLDLRS
                     RALHAKTLTDFRAVRATKATGYRNLKRALAERPPRIWCNFSTLATLAPAPGDVDYCAVN
                     EYLAYASAWAQRHGPDGRHEFAILWSGWREVGVASSTTMRETLKRNRMDAYISTAQGCA
                     QFLSALARPPAGGVSFFIRDEERVLLARRGISTWGTSGGLPAPVPAPDAPPPAPPDPAL
                     TTPLLDGVLHRGKDWAVFTKTWDPRTLVELDGRWMRHHRVNGEYTLPGTFTLEAAAGAA
                     AALCPGLRVTGFRGLVCRTSVTVRLAGPPRTVAVEARVTSRRPGGAEVAVRMTAHRIGK
                     NGKVLRFNDLLCETTVVLADRYPDLAGPPDCSSYEPEPDFAMPVYSPDPPISLTGPFAG
                     TRDYARGPDGCSAGFALDHAAWAPALAGAAVPAILLDAMVHLLLLPPRGDRPPLVGPMA
                     GLDEVDLGGPGNDCRLSAENPVIRLHCDFASGALTAVTGRGRVLARITGVSAHALDHSG
                     DVVRPRGGVPQPPPS"
     CDS_motif       13819..13893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EES43_RS05460_0001"
                     /evalue="3.60E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="EES43_RS05460"
                     /protein_end="37"
                     /protein_start="12"
                     /score="10.0"
                     /tool="antismash"
                     /translation="LVTGAAKSLGADIVRRLAEGGAHVI"
     aSDomain        15439..16890
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05460_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="1.20E-72"
                     /label="EES43_RS05460_PKS_KS.1"
                     /locus_tag="EES43_RS05460"
                     /protein_end="1036"
                     /protein_start="552"
                     /score="237.1"
                     /tool="antismash"
                     /translation="LTLDSACASGLFAVDAAVKALREGSCDVALAGGTAVVEPIGFTLF
                     CRAQGISMSGRVRPFDRAADGTLIGEGAVMLVLKSYARAVADGDRVLGVIRGTGLAADG
                     RGKGIHAPAPRGQELAIARAWADAGVEADDVDWIVAHGTGTPVGDEIELRSLLSRLGPR
                     RKACLLTSNKQVFGHTGVLAGLVSVAHALVALERRAVPGQPVVTDPHPLLGDGSRLTVP
                     VEDRPWPADGTRPRVVGVSSFGLGGADAHVVLSDRVPPAAPAGRRGGAATADAEDLVVV
                     GWNAHLPGLASDRVPAWLSGDGPRPEAGFGTPYPLPSPRDVRIPPLTMRHMDAAHLMML
                     QVLGPLLEQLGEPGAGLRPTTAIVVGSTLPTTHNTRAALRVHARECATAFDILPDPKQA
                     QALKTYLAKGMEDAREVIPGDLNEDDFTGAVSCILSGRAANYYDFQALGTSVYSHRDSA
                     HTAVDLALRQLRHRACDLALVGAVCL"
     aSModule        15439..18786
                     /domains="nrpspksdomains_EES43_RS05460_PKS_KS.1"
                     /domains="nrpspksdomains_EES43_RS05460_PKS_KR.1"
                     /incomplete
                     /locus_tags="EES43_RS05460"
                     /tool="antismash"
                     /type="pks"
     aSDomain        18121..18786
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05460_PKS_KR.1"
                     /evalue="7.80E-24"
                     /label="EES43_RS05460_PKS_KR.1"
                     /locus_tag="EES43_RS05460"
                     /protein_end="1668"
                     /protein_start="1446"
                     /score="76.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VVVAFGGARGITPELLHAVARTSDRPHVYVIGRTPLPESGEPLPP
                     QAEFIAAGRRARPGASVRELRADYEKAQARLEVRRTVHRLTELCGPDRVHHRVCDVLDA
                     ERTTAVLGEVLDRHGRIDLLINTVLDLRSRALHAKTLTDFRAVRATKATGYRNLKRALA
                     ERPPRIWCNFSTLATLAPAPGDVDYCAVNEYLAYASAWAQRHGPDGRHEFAILWSGWRE
                     "
     CDS_motif       19150..19227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EES43_RS05460_0002"
                     /evalue="7.10E-03"
                     /label="PKSI-DH_m2"
                     /locus_tag="EES43_RS05460"
                     /protein_end="1815"
                     /protein_start="1789"
                     /score="9.1"
                     /tool="antismash"
                     /translation="WMRHHRVNGEYTLPGTFTLEAAAGAA"
     misc_feature    20001..20017
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            20001..21014
                     /locus_tag="EES43_RS05465"
                     /old_locus_tag="EES43_05450"
     CDS             20001..21014
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.4"
                     /locus_tag="EES43_RS05465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05450"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_124267645.1"
                     /sec_met_domain="ksIII (E-value: 5.3e-47, bitscore: 158.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLWQNIAIAGTGAWVPPVRPEHGPWNGAATAQPSLAALNGFASAA
                     VSTDSTATQMAARAGLKALRHAGVTGDDLSLLVHANFQDEDHYTPAPYLLRVLGGADTN
                     GIELGAASDGGAAALVVAAEHLTARPDAKAALVTAAGRFPHERWGHSRELGYVAGDAGA
                     AAVLTRTPGFARLAATAHATEPQLETLTRVRKGPAGAERSFLIEETGFMPHIDAMQRST
                     RRCIETVLDETAVRPRDITHVVSIAIGAVVLDLVLAGSPLGVRAGDTAWTFGRHLGHAG
                     PCDILLALDRMFRSGRLRAGERVLVVSFGVGFRWTTALLEVSGNPAATPAGRSEKE"
     gene            21023..22486
                     /locus_tag="EES43_RS05470"
                     /old_locus_tag="EES43_05455"
     CDS             21023..22486
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058024.1"
                     /locus_tag="EES43_RS05470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05455"
                     /product="cytochrome P450"
                     /protein_id="WP_124267646.1"
                     /sec_met_domain="p450 (E-value: 5.6e-75, bitscore: 251.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTRTATAASVPLAPRALPLLGHALPLLRDPLAFIMSLSEYRTM
                     VRVRLGPRSAVMVCDPALTRQVFLNDRVFDKGGPIYDRISEVIGDGLSTCSYTLHRRQR
                     RLCQPSFHPARLAGYGVVFARAAELKAGSWHDGDVLDVTQEMMTLTTRATMETMFSGAL
                     PAETMRRSLADTATIVSAFFRRMMTPPLLRSLPTPRKRRYDDARERLSATIAEIIAERR
                     ADPTDHADLLSALVGAVDEESEDGRKQLNDTELADEALTFFLGGMETTAITLAWALNLL
                     ATHPDVQRRLQAETDGVLAGGKLAPAHLPALGLATRVVTEALRLYPPAWMMTRTLREDA
                     ELGGVRLKRGSVLVLSPYLLHRRPDLYPEPDRFDPDRWLGAQPDRAAYIPFGAGPRKCI
                     GDQFALNEAVLALTAVVARWEVSPVGDEPFRPKVETSLSSRGLALRIGERRPALADAAG
                     LRPAAVPTPAPAGPPDGPGDVCPVTRGER"
     gene            22491..23600
                     /locus_tag="EES43_RS05475"
                     /old_locus_tag="EES43_05460"
     CDS             22491..23600
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="EES43_RS05475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05460"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_124267647.1"
                     /transl_table=11
                     /translation="MKPHLKPLVKQLLGDRRAGLLTATPADALRAPSRPYPNGWFCLAF
                     SDEVRPGSVTTRPLAGAEVVLYRTAAGRLRAVRPRCPHLGAHLGVGGTVEGEDIVCPFH
                     QFAFDPAGVCVRTGYGQPPPKASLAQYPVCEANGSVYVWWHALGLPPRWEVPALPLDDR
                     QPFSHDTFDIAGHPQDVIENAFDWGHLPTLHGLKGLDIEGAPVAGEPVSTVTATARGTV
                     MRGFRQSYSLTVIGLATIAARTVLPRGAGSLYVMLHATATGPGRVQLRFGTKLELSGPP
                     GVPERAGRAAVMPVARLLSAVLQRVASVDTGADLLMWHHQEHVEHPKLARGDGPIGRYR
                     QWAQQFYTEPAGGLAPPGPPRAEARRSEE"
     gene            23708..24601
                     /locus_tag="EES43_RS05480"
                     /old_locus_tag="EES43_05465"
     CDS             23708..24601
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006344984.1"
                     /locus_tag="EES43_RS05480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05465"
                     /product="3-hydroxyacyl-CoA dehydrogenase family protein"
                     /protein_id="WP_124267648.1"
                     /transl_table=11
                     /translation="MAAENGVPGTGHRLAVLGAGVMGSGIAALAVGHGIAVWLIDLDRR
                     RLDEAPARIGHQVRTARLLGALPDGAVPGALVTGLSLAGLMAAGDAVPTAVIEAVTEHP
                     DAKAKVLAEVCALVPPGTPIISNTSAIPVDELALATTRPADLVGAHFMNPPCLIRTVEV
                     IRGTQTGEAALAALRALLAVLRRQAIVVEDAPGFVTSRILHPMINDAVRVVASGTASAD
                     AVDRLMQGCLGHPTGPLRTADLIGLDNLVDSLWVLHGRTGDEGCRPCDLLLEMVRAGRL
                     GRKSGRGFYEYEGEPA"
     gene            24598..24900
                     /locus_tag="EES43_RS05485"
                     /old_locus_tag="EES43_05470"
     CDS             24598..24900
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (26-86). E-value: 5.7e-09.
                     Score: 28.2. Matches aSDomain:
                     nrpspksdomains_EES43_RS05485_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1147: putative acyl carrier protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058022.1"
                     /locus_tag="EES43_RS05485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05470"
                     /product="acyl carrier protein"
                     /protein_id="WP_124267649.1"
                     /sec_met_domain="PP-binding (E-value: 8.7e-07, bitscore:
                     27.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSSDHPVPEPVVGTGDVQADLLRFLARRTGRAWPPDADVFGSG
                     GLSSLFAMEMVVHLERTYGIAIRGADLRMDNFRTVARMAGLVERLRGPGPGGSGA"
     aSDomain        24676..24855
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05485_PP-binding.1"
                     /evalue="5.70E-09"
                     /label="EES43_RS05485_PP-binding.1"
                     /locus_tag="EES43_RS05485"
                     /protein_end="86"
                     /protein_start="26"
                     /score="28.2"
                     /tool="antismash"
                     /translation="LARRTGRAWPPDADVFGSGGLSSLFAMEMVVHLERTYGIAIRGAD
                     LRMDNFRTVARMAGL"
     gene            24893..25999
                     /locus_tag="EES43_RS05490"
                     /old_locus_tag="EES43_05475"
     CDS             24893..25999
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005784.1"
                     /locus_tag="EES43_RS05490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05475"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_124267650.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-12, bitscore:
                     46.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2e-23, bitscore:
                     80.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.9e-31, bitscore:
                     105.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREAVAAAASAVTELVGDRASGWDRAGRLPEDAVRGLGAAGLLSA
                     QIPASHGGPGWSSADSGEFTARVGSLCSSLRSVMTSQGMAAWTVERLGDPGQAADLLPR
                     LASGATAAVAFSEPRAGSDLSAIATTVTVDGDALVLNGRKTWVTAADYADLFLVAARMD
                     EGGAMVVVDRTAPGVRVRRVADPLGCRAAGHAEVRFDDVRLPLGSLLGGGRQPLSLLVT
                     TALAYGRISVAWGCVGILRACVAAAVGHAGSRRQFGRPLGRHQLVARHLADLWTAEQVA
                     TRACEYASRCWDENAAELGTAVVLAKYVSARHAAEGAATAVQVLASAGARDGHVVARAY
                     RDAKLMEIIEGSNEMCQLILAEQALGRC"
     gene            26095..27225
                     /locus_tag="EES43_RS05495"
                     /old_locus_tag="EES43_05480"
     CDS             26095..27225
                     /NRPS_PKS="Domain: FkbH (13-127). E-value: 9e-18. Score:
                     56.5. Matches aSDomain:
                     nrpspksdomains_EES43_RS05495_FkbH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1256: FkbH like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058867.1"
                     /locus_tag="EES43_RS05495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05480"
                     /product="HAD-IIIC family phosphatase"
                     /protein_id="WP_124267651.1"
                     /transl_table=11
                     /translation="MSDTAPAVPPATVKCLVWDLDNTLWRGTLLEDEDVVLTEAIRAVV
                     TSLDARGILQSVCSRNDHDHAWARLEALGIADHFVLPEIGWGPKSAAVRRISERLGFAP
                     GTIAFIDDQPAERAEVAHHLPDVRCYPAEAAATLPGLPEFSPRTVTADSRQRRRMYQSG
                     FRRADERALFTGSHEDFLRSLDMVLSIGRATEEALSRVEELTLRTSQMNATGVHYPIEA
                     LRTLIAQPSHEVLVATLSDRFGPHGAVGVTLLRKHPEAWHLRLLATSCRVVAYGVGTVI
                     LNWLVDQAARAGVHLVADFRATDRNRMMEIAYRFAGFDERPCRCRDRISGDSGEDVQLL
                     HLVAERRSAPAVVRLIAPELTDRAPGRAGVTSGGPE"
     aSDomain        26134..26475
                     /aSDomain="FkbH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EES43_RS05495_FkbH.1"
                     /evalue="9.00E-18"
                     /label="EES43_RS05495_FkbH.1"
                     /locus_tag="EES43_RS05495"
                     /protein_end="127"
                     /protein_start="13"
                     /score="56.5"
                     /tool="antismash"
                     /translation="KCLVWDLDNTLWRGTLLEDEDVVLTEAIRAVVTSLDARGILQSVC
                     SRNDHDHAWARLEALGIADHFVLPEIGWGPKSAAVRRISERLGFAPGTIAFIDDQPAER
                     AEVAHHLPDV"
     gene            complement(27203..27865)
                     /locus_tag="EES43_RS05500"
                     /old_locus_tag="EES43_05485"
     CDS             complement(27203..27865)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961925.1"
                     /locus_tag="EES43_RS05500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05485"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_124267652.1"
                     /sec_met_domain="Methyltransf_3 (E-value: 5e-67, bitscore:
                     223.6, seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 4e-05, bitscore: 21.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQQTSIGPELLRYVREFSLREDEILCELRRSTAELPGGESQQVM
                     AEEGQFLAFLVAATGVRDVLEIGTFTGYSTLCMARALPPQGSLVTCEVSERWTEIAADF
                     WRRARVRERIDVRVGAAVDTLEELLAEGRLGSFGLVFIDADKANYPRYYELALRLVRPG
                     GLLVLDNTLLAGRVIDPAAQDADTAGIREVNARIRDDPRVDVCMLPVADGITLVRRR"
     gene            complement(27943..28176)
                     /locus_tag="EES43_RS05505"
                     /old_locus_tag="EES43_05490"
     CDS             complement(27943..28176)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039952.3"
                     /locus_tag="EES43_RS05505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05490"
                     /product="DUF5988 family protein"
                     /protein_id="WP_124267653.1"
                     /transl_table=11
                     /translation="MIGEDEARAGRLVVLSGGPPELPRVQRLPVGCVADASRLIVAFYG
                     RHQRFVRTGETEQVEGRTVPVFRFDYSTKIAE"
     misc_feature    28195..28213
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.44"
                     /tool="antismash"
     misc_feature    complement(28231..28245)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.1"
                     /tool="antismash"
     misc_feature    complement(28361..28370)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.4"
                     /tool="antismash"
     misc_feature    complement(28453..28468)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.58"
                     /tool="antismash"
     gene            28521..29972
                     /locus_tag="EES43_RS05510"
                     /old_locus_tag="EES43_05495"
     CDS             28521..29972
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512192.1"
                     /locus_tag="EES43_RS05510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05495"
                     /product="penicillin-binding protein 2"
                     /protein_id="WP_124267654.1"
                     /transl_table=11
                     /translation="MNKTIRRASAFCLLLVLALLVRATWVQAYEARALADNEHNRRNTI
                     AQYAQPLGDIIVAGSPVTGSKETSGGDLRHKRTYTQGELYAAVTGYSSQAYGATQLEGI
                     YGDVLDGTDSRLKNPADLLTGAQAAPGDVVTTIDPDVQKAAYEALGDDKGAAVAIDPKT
                     GRILAMVSTPSYDPSAISGTADGDAWQALLADRDKPLTNRALRQPLAPGSTFKLVVAAA
                     ALENGLYGSVDEATDSPDPYTLPGTRTVLRNENASAPCENATLRTALQYSCNNVFAKAA
                     ADLGQDKVKEMADAFGFGTEKLDVPVRAAESVYPTGMDAAQTALTGIGQFEVTATPLQM
                     AMVTSALANGGELAAPHMVSEVTDGGGSTLEETADGASKRVVKESTAEQLRSAMVTVVE
                     EGTGTNARIAGAEVGGKTGTAQNGVDNSNTPYAWFTSYAKDRASGKEVAVAVIVEDSGS
                     ARSEVSGNGLAAPIAQKTMRAALGR"
     misc_feature    complement(28522..28536)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            complement(30076..31266)
                     /locus_tag="EES43_RS05515"
                     /old_locus_tag="EES43_05500"
     CDS             complement(30076..31266)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055997.1"
                     /locus_tag="EES43_RS05515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05500"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_124267655.1"
                     /transl_table=11
                     /translation="MSLTFHWFLPTNGDSRHVVAGGHGAPVTPTGGDRPPTVRYLAQIA
                     RAAEDAGFTGVLTPTGAWCEDAWLTTAMVSQHTERLKFLVAFRPGFVSPTLAAQMASTY
                     QRQTGGRLLLNVVTGGESHEQRAYGDFLDKDARYARTGEFLEIVRRLWDGRTTDLHGEH
                     LRVEQARLTRLPDPVPEIYFGGSSPAAGAVAARHADVYLTWGEPPAQVAEKIAWIRRLA
                     AEQGRTVRFGIRLHVITRDTSDAAWAEAARLLDGFDGATVRGVQEGLARSESEGQRRML
                     ALHGGGRDGLEIHPNLWAGIGLVRGGAGTALVGGHAEVAERITEYHRLGIDEFVLSGYP
                     HLEEAYWFGEGVLPRLAAAGLWAHPAAPPPTDRRGTEIPFTAGAGAGAGAGAAASG"
     gene            complement(31338..31892)
                     /gene="ssuE"
                     /locus_tag="EES43_RS05520"
                     /old_locus_tag="EES43_05505"
     CDS             complement(31338..31892)
                     /EC_number="1.5.1.38"
                     /GO_function="GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA]"
                     /GO_process="GO:0044273 - sulfur compound catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ssuE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015607799.1"
                     /locus_tag="EES43_RS05520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05505"
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="WP_124267656.1"
                     /transl_table=11
                     /translation="MATVLSVSGSPSATSRTARLLRHLDADLAAQGHEVIPLDVRTLPA
                     EALLGADFAHPEIVRAAELVARADGVVIGTPVYKAAYSGLLKSFLDLLPQYALTGKTVL
                     PLATGGTTAHVLALDYALRPVLSSMGAAHIVQGWFVLDRHIAADDDGTVVLDPASAAPL
                     DQVVAQFAAALGRTAPVPAAR"
     misc_feature    complement(32020..32034)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            32454..33362
                     /locus_tag="EES43_RS05530"
                     /old_locus_tag="EES43_05510"
     CDS             32454..33362
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994771.1"
                     /locus_tag="EES43_RS05530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05510"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_206429994.1"
                     /transl_table=11
                     /translation="MRIEQLEYIEAVTRLGSLRRAAEELHLSQPALSETVRNLERELGV
                     TVLDRKRSGATISDAGRELLPHIIGVLDAVDRLRRAADEQHRTSRTVRLGTVFAATVPL
                     LVPAIRTFHTLHPATEVEVIAAQQSAIHRSLLEGGVDLGLVNYLEGDDQAPDLHTTELL
                     RGRPVVCLRPDSPLASRESVGVEDLLGAPLIVMRAGYVMHRFTHRLLKGRSPSFSYAAD
                     GAEMGKLMVAEGLGVTLLPDYSVVGDPLERAGAITWRPLAADTTTVLLVLQRSRSGSVT
                     RAARDLHRILVERAEAHRADG"
     gene            <33427..>33525
                     /locus_tag="EES43_RS31145"
                     /pseudo=""
     CDS             33427..>33525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957672.1"
                     /locus_tag="EES43_RS31145"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKPTAEQGEPAPDDPAHAYVGGHCVTDPPVWPH"
     gene            33599..34822
                     /locus_tag="EES43_RS05540"
                     /old_locus_tag="EES43_05515"
     CDS             33599..34822
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381420.1"
                     /locus_tag="EES43_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05515"
                     /product="TerD family protein"
                     /protein_id="WP_124267658.1"
                     /transl_table=11
                     /translation="MTAMTPGSNIPLSVARVAVDVAAPVRLDVSGLLLTADGKVRSDDD
                     FIFYNQPSGPGVTYRSGGGSSPDAIVVDTAALPPGIEKIVVTASPDAEGQTFQGVEPTA
                     TVRNADDGTALATFTPPRLGSETALVVIEIYLRNGAWKARAVGQGYANGLAGIATDFGV
                     TVEEPAAPVPAAAPAAPAAPAAPAAPAAPRITPPAPASAAPPAPPAAAPAASGKINLDK
                     GRVNLQKNQTVSLVKGGAPLLSQVKMGLGWEPAFRGKDIDLDASVIAYGPNRNHLDSCY
                     FGKLAILNGSIKHSGDNLTGEGAGDDEVIVVDLGRIPAEATGLVFTVNSFTGQKFNEVA
                     KAYCRLIDAATGEELVRFDLTGAEPQTGVMMAKLIKQFSGEWEMTAIGEFVKSRTVRGM
                     VKPASKAL"
     gene            complement(34945..35175)
                     /locus_tag="EES43_RS31150"
                     /old_locus_tag="EES43_05520"
     CDS             complement(34945..35175)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104640.1"
                     /locus_tag="EES43_RS31150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05520"
                     /product="hypothetical protein"
                     /protein_id="WP_003969918.1"
                     /transl_table=11
                     /translation="MKQSAGSRRHLPSSPFNRPAQEAPPVECFDVGDRVSHDQFGLGRI
                     LAVEGDNDAVLIDFSGRQGRILSPYSKLTKL"
     gene            complement(35445..36914)
                     /locus_tag="EES43_RS05545"
                     /old_locus_tag="EES43_05525"
     CDS             complement(35445..36914)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156923.1"
                     /locus_tag="EES43_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05525"
                     /product="hypothetical protein"
                     /protein_id="WP_124267659.1"
                     /transl_table=11
                     /translation="MSAERPTLPPVRLTSEAELARDALAAPLFVRAVRLARWAGPETRV
                     GAGGELAEAQLPAAAEHLGLPADEDGAAYASEAWRLAVDTGLLDVTDPEEDEPSDEAEG
                     TVTQGENLALLTGGSPQDVLGIWLDGLDAVHADATAPVLDDFADLVGEDGSIDFDALDW
                     DPEAEAEFLDGVLGNLYLLTLADNGAGDGPVPLPALAASMIVPDDMGEPTDDILEQVSE
                     AMMRLDDQFRLLEPIGIIEYQPVDESLMVEAGEEDAAGASDEDDVTRYGMVRLTPLGLY
                     GVRARMLEAGVDAPAVGDLAGKGADALLDGIAHYPESAARAEVGLWLAGFGAEGSVAAA
                     AELLAAARGTDAGAPLRRLNCQQALALAGPEAEPAVRAVLGDAELGGLARVWLAERGAA
                     DVPVPPESMIFWLAIDTIAAQLDADGDLDELQGLIEGLSAQHSGFFDEVWRVDHPATAD
                     VLEAMGRLHGDKKAAKEARKAAFKARSRAAD"
     misc_feature    37072..37087
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            complement(37227..38225)
                     /gene="dapD"
                     /locus_tag="EES43_RS05550"
                     /old_locus_tag="EES43_05530"
     CDS             complement(37227..38225)
                     /EC_number="2.3.1.117"
                     /GO_function="GO:0008666 -
                     2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="dapD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007498259.1"
                     /locus_tag="EES43_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05530"
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="WP_124267660.1"
                     /transl_table=11
                     /translation="MTDTTSQGSSRTTGAVAAGLATIAGDGTVLDTWFPAPELTSEPGP
                     AGTERLGPDEAVNRLGEGAAKAIGVDARRGVEVVAVSTVIASLDDKPLDAHDVYLRLHL
                     LSHRLVKPHGQNLEGIFAHLANVAWTSLGPVAVDDLERVRLNARAEGLHLQVTSVDKFP
                     RMTDYVAPQGVRIADADRVRLGAHLAAGTTVMHEGFVNFNAGTLGTSMIEGRISAGVVV
                     GDGSDIGGGASTMGTLSGGGKERIVIGERSLVGAEAGVGIALGDECVVEAGLYITAGTR
                     VTLPDGQVVKARELSGASNILFRRNSVTGTVEARPNNAVWGGLNDVLHAHN"
     misc_feature    complement(38225..38242)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.54"
                     /tool="antismash"
     gene            complement(38270..38875)
                     /locus_tag="EES43_RS05555"
                     /old_locus_tag="EES43_05535"
     CDS             complement(38270..38875)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156919.1"
                     /locus_tag="EES43_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05535"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_124267661.1"
                     /transl_table=11
                     /translation="MARRYDPDRRTRIVDAALRVVAAHGMAGLSHRTVAAEADVPLGST
                     TYHFGSLDELLVAALRRLDENFARTLRESPVLAAEPSGEDGGGPAGLADELTRLLERWF
                     AGESGAAELEYELYLAALRRPALRPVAAEWADAAVGVLSRHTDPATARALVALMDGICL
                     RALLTGSAFDAGHTREMLARIIPAPGGARAGASPEAGG"
     gene            complement(38875..39201)
                     /locus_tag="EES43_RS05560"
                     /old_locus_tag="EES43_05540"
     CDS             complement(38875..39201)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061314.1"
                     /locus_tag="EES43_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05540"
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_124267662.1"
                     /transl_table=11
                     /translation="MGYAYGLLAGAIAAEVAGTTAMKYSEGFTRLWPSLATVVGYVIAF
                     TLLAQTLKTLSVGTAYAIWAGAGTAAVAAIGILFLGESAGAVKLAGIALIIVGVVVLNL
                     GGAH"
     gene            39489..40475
                     /locus_tag="EES43_RS05565"
                     /old_locus_tag="EES43_05545"
     CDS             39489..40475
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969899.1"
                     /locus_tag="EES43_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_05545"
                     /product="hypothetical protein"
                     /protein_id="WP_124271798.1"
                     /transl_table=11
                     /translation="MLSGAFSTLGRYWKPLIGMALTLFGAATLVMAVALVVAASTVASK
                     WDELTSGSPDAPDAAELVPLGVAFSVLMVLGVAAYLLASAVVQAAVPVVLQEAVLGRPI
                     RFGAVWSRAWSRAWSVIGTALVMGLVAIIPMAFFMTAFAGLMVYLVSLGDEHGVLPMMW
                     FGLLGALLVAPAATWLYVRFSLAPTIVVFEKQRPVAALRRSARLVRDSWWRVFGVGLLA
                     YAMAAVIALMIQGPFQLAGALPGLFERADTTAERSGGEMIALFGGLMLLSLVSQLVAQL
                     FTAIFPPLMVGLLYVDRRMRTENLGPILAEAAGRTLPEQYGPPPAQS"
     misc_feature    complement(40798..40814)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    40975..40995
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.56"
                     /tool="antismash"
ORIGIN
        1 ccgcctgtgg agccgccggt ggaacctgcc gtcgaaccgg tcgtggcgcc tccgtcgccg
       61 gaggagccac cgtccgtacc gcccggcttt ccgggcgtct tcggggtctc gcaggtcgcc
      121 tcggccagcg tgacgtcccc ctccacctcc gcgacgttga gcttcagcgg gttcaccgag
      181 accttgagcc ggagagcggt cgcggcggcg gtacgcgtgg tggtggccgt cttcgagagg
      241 tcgagggtga cctcgccgac gcccggcacc tccaccctgg tcgtcccgct cgccgtgagg
      301 gtcagcttct tgccgaggac cgcgatgtgg ccgagcacgt tcgactgggc gacgggcttc
      361 ttcccgacct cgcacagcgc cttggaggtc accttctcga cctcgatcag cgagagcagc
      421 ggcagtccgg gcaggtggat ccgggccttc acgaggttgg tgtagccctg ggcccggtgc
      481 tcgtcgaccg tggcgtcggc ggtggccacg tcggcgcgca ggacgctgaa cggccgcccc
      541 cggtccacac cgtccaggtt cacgctgagc gcggtcttct cggcgctcgc cggcgcctgc
      601 acctcgttga gggtgacctt gaggggcacc tggacggtct tgttcaggag cgagacgccg
      661 agaccggtgc ggagcacgac cgcgctcgcc ctgccctcgc ccgtggtcgc gggcgtcgcg
      721 gtggctgcct gcgcggggac ggcggcgagc agggcgacgg gagcggcggc gaccgcgagg
      781 gcggcgagac ggaaggtgtt gctgttcaag atggtggaac ccccacaaga gacatggagc
      841 caccggcgcc gtccaatggg ggacatcgcg tgcgccggtg gcctcgactc cgtgaatctt
      901 tacgcacgga gggtgaactg gtggatacct gaggtgagtt caccccaaag gggggtttcc
      961 gctcgcatat tcgaatcttt cggcacgtgc gttccctggt gtcactcgtt tcacggagcg
     1021 tgagcacggc gggagttgac cgcacggcca tccgccccgg tccggggcga aagtgcttca
     1081 acgagccggg gccccgtccg acactgccgg tcaacaccgc gccggacggg ccgggtccgg
     1141 ccggccgggc tcagccgacg atccgcccgt tcagcacgac gtgccgcggg gccgccagca
     1201 cccgtacgtc ggcgcgcggg tcctcgtcgt agacgaccag gtccgccggg gcgccctcct
     1261 ccagcacggg ccgccccagc caccgccgcg ctccccacgc ggtggcggag agggcttcca
     1321 gcggcgggat gcccgccttg accagctcgg cgacctcgcc cgcgaccagg ccgtgcgcca
     1381 gcgaccctcc cgcgtcggtg ccgacgaaga ccgggatccc ggcgtcgtac gcggcgcgca
     1441 cggtgtcgta gcggcgctcg tacagctccc gcatatgggc cgaccagcgg gggaacttcg
     1501 cctctccgcc cgccgcgagg tccgggaagg tggcgatgtt gaccagcgtc gggacgatcg
     1561 ccaccccgcg ctcggcgaac agcgggatcg tgtcctcggt gagcccggtg gcgtgctcga
     1621 cgcagtcgat gcccgcctcc accagatcgc gcagggcgtc ctcggcgaag cagtgcgcgg
     1681 tgacccgcgc gcccagccgg tgcgcctccg cgatggccgc ctcgacctcc ccgcgcggcc
     1741 agcaggcggt gaggtccccg gcgtcccggt cgatccagtc ccccaccagc ttgacccagc
     1801 cgtcgccgcg gcgcgcctcg cgcgcgacgt acgcgacgag gtcgccgggc tcgatctcgt
     1861 gggcgtagtg gcggatgtag cggcgggtcc gggcgatgtg ccggcccgcc ctgatgatct
     1921 tcggcaggtc cgcgcggtcg tcgatccacc gggtgtcgga cggcgatccc gcgtcgcgga
     1981 tgagcagggt gcccgcctcc cggtcggtga gcgcctgctt ctcggcggtg gcggcgtcca
     2041 ccgggccgtg ccggtcgagc cccacgtggc agtgcgcgtc gaccaggccg ggcagcgccc
     2101 agcccgtgac cgtcaccgcg tcgtcggcgc ccgggggccg ctcgtggacg atccggccgt
     2161 cgaccgccca cagttcgtcg cgcacctcgt ccgggccgat gaggacccgc cccttcaccc
     2221 gcagcacccg ctgcccctcc tgatcactca tatgcggcac tgtacgaggc cctcggtacc
     2281 ctcgtcggag caccgtcgtc gagccggacc aagccgaccc gacccccggc cgaaccgaag
     2341 agagcaccac cgtgacgcac cccttcctcg atctcccccc gctgaccgcc gcgcacttcg
     2401 ccgccatcga gcggcgcgtg gcctcgctcc tggccacgga gcaggacgtc gtcgtcatgc
     2461 agggcgaggc gctgctgccg ctggagggct gcatccgcgg cggcgcgcgg cccggttcga
     2521 ccgcgctgaa cgtggtcacc ggcccgtacg ggcagacctt cggcgactgg ctgcgcgact
     2581 gcggcgcgga ggtcgtcgac ctgaccgtgc ccttccacgc ggcggtgacg gccgagcagg
     2641 tcgccgaagc gctcgcggag cgcccggaga tcgacttcgt ctcgctggtg cacgcggagg
     2701 cggcgaccgg caacaccaac ccggtcgcgg agatcggcga ggcggtccgc gcgcacggcg
     2761 cgctgttcat gctggacgcc gtggcctcgg tgggcgcgga gccgctgctc ccggacgcgt
     2821 ggggcgtcga cctgtgcgtg atcggcgcgc agaaggcgat gggcgggccg gccggggtgt
     2881 cggcggtgtc ggtgagcgag cgggcctggg agaggttcgc cgccaacccg gccgcgccgc
     2941 gacgctcgta cctctccctc ctggactgga aggagcgctg gatcgacgcc ggccggacgg
     3001 ctctgccgca cgcccccgcg cagttggaga tgctggccct ggaggcgtgc gtggagcgga
     3061 tcgagaacga ggggccggcc gccgtgatgg cccggcacac cgctgctgcc gccgccacgc
     3121 gggccggcgc ggtggccctc ggcggcgggc tggagcccta cgtccacgag gcgcgggacg
     3181 cggccccggt ggccacgacg ctgcgcgccc cggcgggcgt cgacgcgacc gcgctggtcg
     3241 cccacgcgcg ggcggcccag ccctcgctgc cgctcatcgc gggcggcggg gcgctgtcca
     3301 aggagatgat ccgggtcaac cactacggtg cggacgcgac gcggggcgcg gtgctctcct
     3361 cgctcgccgc tctgggggcg gcgctggccg acgcgggccg gcaggtcgat ctcgaagctg
     3421 cccgcaaggc ggtcggggaa acctggccca gcgcctgaat tcgtcggacg tcatgccgga
     3481 tccgctaggg cgtcatgaat ccataaatgc ggggagctgc tttatccgaa gcagctcccc
     3541 gcattcttct tcccgctttc tttctgccta aacgcccagg tttccgaggg tgggagctcc
     3601 gtgattcgag ggcgtctccg cgaggttacg gccctgtgac cgactccaca tgaggcgcgt
     3661 tatgccggaa aaattccggt caaagggtgc taaatcgctg cggtttcgcg caagggcacg
     3721 cgcccgcctg ataacagaga acgcccaccg aaccaacccc ttacctcgat gcaattttga
     3781 aatttgctgg gtaaattcac ttcacatgac cgccgcacca gcagatgttg cccgtgcccg
     3841 aagcgaattc ctcagtatcg acaccccgcg agtggaggac ggagccgcga tctggcgcat
     3901 tgcccgcgac tccgaggtcc tggacctgaa ttcctcgtac agctacctgc tgtggtgccg
     3961 cgacttcgcc gcgacctccg tcgtcgcccg cgacgagacc ggcgagccga tcgccttcgt
     4021 caccgggtac atccggcccg accgccccga gacgctcgtc gtctggcagg tggcggtcga
     4081 ccgggagcac cgcggcaggg gactcgcggc caccctgctg gacgcgctga ccgcccgggt
     4141 cgccgccgac cagggcctcg cagcggtcga gacgaccatc accccggaca acaccgcctc
     4201 cgaccggctg ttcacctcgt acgcgcggcg ccacgacgtg cccctggagc aggaggtgct
     4261 gttcgacggc gagctgttcc ccgagggaac gcacctgccg gaggtgctgt accgcatcgg
     4321 accgttcacg tcctgacacc cgtcgcaccg gccgcgcgac gacgcccgcc ccacgaagcg
     4381 ggccgcgcgc gacgtccgcc ccacgacttc cgcgccggtc cggccgcccg gcgcgacgcg
     4441 atctggcttc cgccgccgga agcaccccga ccactgtccg tcacaccccc tcacgcagga
     4501 gatcagctgt gaccatcacc ccgcccgcac tgagcgtctt cgagaccctg gagtcggagg
     4561 tacggagcta ctgccgcggc tggcccgccg tgttcgaccg cgcgcagggc gcccgactga
     4621 ccgacgagga cggccactcc tacctcgact tcttcgccgg ggccggctcg ctcaactacg
     4681 gccacaacaa cccggtgctc aaacgcgccc tcatcgacta catcgagcgc gacggcatca
     4741 cccacggcct ggacatggcg accaccgcca agcgcgcctt cctggagacg ttccagaacg
     4801 tgatcctgcg cccgcgcgac ctgccgtaca aggtgatgtt cccgggcccg accggcacca
     4861 acgccgtgga gtcggcgctg aagctggccc gcaaggtcaa gggccgcgag tcggtcgtct
     4921 cgttcaccaa cgccttccac ggcatgtcgc tgggctcgct cgccgtcacc ggcaacgcgt
     4981 tcaagcgggc cggcgccggc atcccgctgg tgcacggcac cccgatgccg ttcgacaact
     5041 acttcgacgg ccaggtgccg gacttcctgt ggttcgaacg gctgctggag gaccagggct
     5101 ccgggctcaa caagccggcc gcggtgatcg tggagaccgt gcagggcgag ggcggcatca
     5161 acgtcgcgcg cgccgagtgg ctgcgcgcgc tccaggacct gtgccaccgc caggacatgc
     5221 tgctgatcgt cgacgacatc cagatgggct gcggccgtac cggcggcttc ttctccttcg
     5281 aggaggccgg catcgtcccg gacatcgtca cgctgtcgaa gtccatcagc ggctacggcc
     5341 tgccgatgtc gctctgcctg ttcaagccgg agctggacat ctgggagccg ggcgagcaca
     5401 acggcacctt ccgcggcaac aacccggcgt tcgtcaccgc cgccgccgca ctggacgcct
     5461 actgggcgga cggccagatg gagaagcaga ccctggcccg cggcgagcag atcgagcagg
     5521 cgctgctggc cgtctgcgcc gaggagccga ccgcgcactt ccgcggccgt ggcctggtct
     5581 ggggcatgga gttcgaggac ccgacgcgcg cttcggcggt ctgcgccaag gcgttcgaac
     5641 tggggctcct gctggagacc tcgggcccgc agagcgaggt cgtcaaactg ctgccgccgc
     5701 tgaccatcac ccccgaagag ctggacgagg gcctgcgcac gctggcccgc tgcgtccgcg
     5761 agacggcctg aaccggcgcc ggccgggcag gcgagaagag aggccccggg ccccgctggg
     5821 cccgggacgc cgcagagaga aaggcacaag ctcaccgtga tcgttcgatc gttcagtgac
     5881 atcgagaaca ccgaccgcca cgtgaaggcg gcgtccggca cctgggagag caagcgcatc
     5941 gtgctcgcca aggagaaggt gggcttctcg ctccacgaga ccgtgctgta cgcgggcacg
     6001 gagacgtcga tgtggtacgc caaccacatc gaggcggtgc tctgcaccga gggcgaggcc
     6061 gagctgacca acgacgagac cggggagacc cactggatct ccccgggcac gatgtacctg
     6121 ctggacggac acgagcacca cacgctgcgg cccaagaccg acttccgctg cgtctgcgtc
     6181 ttcaaccctc ccgtcaccgg acgggaggac cacgacgaga acggtgtcta cccgctgctg
     6241 accgaggagg gctgaacatg accaccgaag tacgcgccga cctgtacccg tcgcgcggcg
     6301 ccgccgagat gaccactccc cgccaggacc cggtcatctg gtccgcgccg ggcgcaccgg
     6361 gcccgatcgc cgcgaaggat ctccagggct acgagcacga cgggttcctc accgtcgacc
     6421 agctgatcac accggacgag gttgcggtct acgaggccga gctgaaccgg ctggtctccg
     6481 acccggcggt acgggccgac gaccgctcga tcatcgagcc gacgtcgcag agcgtccggt
     6541 ccgtcttcga ggtccaccgg atcagcgagg tcttcgccgc tctcgtccgc gacgagcggg
     6601 tggtgggccg ggcccgccag atcctcggct cggacgtgta cgtccaccag tcccggatca
     6661 acgtgaagcc gggcttcggg gcctcgggct tctactggca ctcggacttc gagacctggc
     6721 acgccgagga cggtctgccg aacatgcgga cggtgtccgt gtcgatcgcg ctgaccgaga
     6781 acttcgacac caacggcggg ctgatgatca tgcccggttc gcacaagtcg ttcctcggct
     6841 gcgcgggcga gacgccgaag gacaactaca agaagtccct ccagatgcag gacgccggca
     6901 ccccgtccga cgaggcgctg acgaagatgg ccgaccggca cggcatcagg ctgttcaccg
     6961 gccgggccgg ttcggcgacc tggttcgact gcaacgccat gcacggctcg ggcgacaaca
     7021 tcaccccgta cgcgcgcagc aacgtcttca tcgtgttcaa cagcgtggag aacgaggcgc
     7081 aggagccctt cgcggctccg atccgccgcc cggagttcat cggggcgcgg gacttcactc
     7141 cggtgaggta gcacggcgag gtagcgagat agcacggcgc acgcgcgacc ggggccggga
     7201 cgggcatgcc gtcccggccc ccgcgcgtgc ccgcccgtcc ggtcggcctc acgccgttcg
     7261 gacggtccga cgcgttcagg cggttccgag cgccgggtag tcggtgcagc ccttcgcgtc
     7321 ggcggccagt gatcggtcgg cggtcggcgg tcggcggtcg atcaggccag cacgtccagc
     7381 agccggtcga cgtgcgcttc ggtgttgtag aggtggaagg acgcccggag gtttccggcc
     7441 cggtccgaga ccctgatgcc ggcccgcgcg aggtcctcct tgcggtggcc gagccccggc
     7501 accgcgacga tcgccgactc cccgggcacc gcctcgtgcc cgagaaccgc cagccccgcg
     7561 cgcagccggg ccgccaggga ggtggcgtgc gcgtggaggg cgtcgacgcc gacctcgccc
     7621 agcagggcca gcgaccgctc ggccccgtgg taggagagga aggcgggcgg ctcgtcgaac
     7681 cgccttgcgg tgggggcgag ttcggcggga ccgtacatcg cgttccaggg cgctccggag
     7741 gagatccagc ccgcgaagag ggccggcagg tgggcctgtg cctcctcggt gacggtcagg
     7801 aacgacgtac cgcgcgggca gagcaggtac ttgaagccgc cggtgacggt gtagtcgtac
     7861 tcccccgcct ccagcgggaa ccagcccgcc gcctgcgtcg cgtccaccag cgtgcgggcc
     7921 ccgtgcgccg cggcggcggc ccggacggct gccaggtcgg ctgtccggcc gtcggccgac
     7981 tgcacggcgg agaaggcgac gagcgccgtg tccggccgca ccgccccggc cagcccggcg
     8041 agcgggacgt accgtaggcg caggtcgctc cggtgcgcga acgggctgac cagcgagctg
     8101 aactcgcctt cggggcagag gacttcggcc tccggcggga gggaggccgc gatcagcccg
     8161 acgtggacgg cgaccgagcc cccggtcgcc acccggtccg ggtggacgcc gacgagccgt
     8221 gcgaagccgg tgcgggcgga ctccacggcg tccagactgc ccgcgccgac ccggaggccc
     8281 gcggcgttct cgtcggcgag tgccttgacg gcggcgatcg tacggcgggg cagcaggccc
     8341 caggtcgagg tgtcgaggta cgtggtctcc ggggcgaact cggcggtcgc cgcttggctg
     8401 agcgcagtga tcctcatgcg cccagcctgg agtcctggtg aaccgccgtc aatcacgtat
     8461 cgcccggggc ctccgcgccg ggtgaggcgg cgggtcgggc gaggcggcgg ctcagtcggc
     8521 gcgcgggacc tcgcaggccc cgtcggcgtc gcaggccgcc gcgtcgccgc cgaccggggt
     8581 cagcgcggtg gcccggtggt ccttccacgc ctgctccagc gcctggacga agacctcgga
     8641 gggctggccg ccggagatcc cgtagcgccg gtcgagcacg aagaacggca ccgcgttggc
     8701 gcccagctcg gacgcctcgc gctcgtccgc ccggacgtcg tcggcgtacg cctcggagtc
     8761 ggcgagcacc gcccgcgcct cgccggcgtc gagcccggcc tccacggcga gggcgaccag
     8821 cacctcgtcg tcgaagacgg agcgctcctc ggcgaagttg gcccggtagg cgagggtcag
     8881 cagttcgtcc tggcggcccc gggccttggc caggtggagc agccggtgaa tgtcgaaggt
     8941 gctgccgtgg tcgcggccct ctacgcggta gccgagccct tcggcccggg cgttgtcggc
     9001 cacgttggcc tccatcgagg cggcttcctc acgggtccgg ccgtacttgg cggccagcat
     9061 gtcgaccacc agcgcccggt cgcccttggc ccgtcccggg tcgagctcga aggagcggtg
     9121 gacgacctcg acctcgtcac gatgggcgaa ccgagccagg cccttctcga agcgtgcctt
     9181 gcctatgtag caccacggac aagcgatgtc gctccagatc tcgacgcgca tggctcttct
     9241 tctctcccgg gatcgcgaac ggtgcgaagt ctccctccgc actgggcggc cccgcgcgga
     9301 tcgacctgac acaccagggg cctccaggtc gaacacggaa cctgacctgc gcattcccga
     9361 cccgggagag caccgcgcct ggagccgcca ggagagaggc tgccggggtg gagggcacac
     9421 gaagcacctc taggatcaga agacggacga cctcgcgtgg cgtgtgtccc tgcgaccgct
     9481 gatgaatgga cagcgttgcg taattgaggg aggtccgtgc tccgactgca tagcgccctc
     9541 agttcctgtc gccctcccaa cggtaccgcc gagcctggcc gggtagttat ctggagcaga
     9601 gcaggagagc gacggacggg gtacaggcgc cctgacaccc gatcgaaagg aagtcagtca
     9661 tgcgttcctg gattctgggc aactgcgacc atgagtggac gcagtggagt ggcaagcagc
     9721 gctgccggaa gtgcggcacg acgcaaggct gagggctgcc ccgtgggcag gaagcgtgag
     9781 ggggccgagg cgaccggccc cctttaccca cgatcgaaag tagaaacggt gctcgaacgt
     9841 gttcgctggg aagaactgcc ggccgagttg cgcgacgcca tcgagaccaa ggcaggtgaa
     9901 gtcaccgagt cggaggtggt tgccgaaggt ctcaactgct ccacagctct gatgatccgc
     9961 acggagaaac acgggtcgct gttcctcaaa ggggttcgcg agaacgtcac ggtagaggtg
    10021 ggcgcgctgc ggcaagagga acgagtgaac ggcgctctcg gtggaatcag tgcccaactc
    10081 cgccaccgct ttcggctcgc cggttggtac tgcctgacgt tcgagtacgt ggacaacggt
    10141 cgccacgcgg acatgacccc aggatcaagc gaccttgatg ccatcgggtt cgcactcgac
    10201 cggatgcaac aactcgtttt cccgaacctt ctgccgtacg ggcggttcca gttcaccgtc
    10261 cccaccctgg ccgaccggtt cgaagatttc atcaacactg ccgagtcccg cgcgctccag
    10321 ggcgacaacc tgcttcacac cgacatcaac ccctacaaca tcctcatgta cggggcgcac
    10381 aacagccgcg cctgcgtggt ggattgggcc atgcccgcca ctggccccgc ctgggttgat
    10441 ccggcataca ccgcagtgcg cttgatggaa tgcgggcaca cccccgctgc cgctctgaaa
    10501 tggcttgggg ggttcacaag ctggcagtac gcggatccgg aatccgtaag ggcactcgtg
    10561 aatgcggtgt gccgccagtg gacggcgcgg gtcggggaga aggacgcccg atacagcaac
    10621 gggaactacg agcacctcct cggctacccg cacaagacgg ggaagcgtcc cacgtcgcgg
    10681 aagcgcccgc cgggctgagc cccgaaccgg ccctgccgcc cgtcagcttt cccgggagcg
    10741 aacgggcggg ccgcttccac ctctaccggg gcgggtttcg gcgctgccag gtccttcttc
    10801 ggcacctgct tcggcgaggc ggcgttcgtc gatgccgggt tcgtcaccgt cgggccggga
    10861 ggctcctctc catgcggcgg tcacggctcg ttcggcctcg ctccggtccc gtgacccgcg
    10921 tgcggcgtcc cggaagcgtt tgggcggaat gccggtcgcc cgcttgaagg cgtggctgaa
    10981 ggtgctctcg gaggcgtagc cgagggagag cgcaagctcc gacaccggag tgtccttctg
    11041 gatcagggtc ttctcggcca gccgtatgcg ccactggtgg aggtaggtga gcggtggcac
    11101 gcccgccacc gacgtgaaga ctccggcgaa tacgctgcgg gacatggccg ccgcccgggc
    11161 gagttcggtc acgtgccagg gccgggcggg atcggcgtgc atcagcctca gggccggcgc
    11221 gatgcgttcg tcggccagag cccggagcca ccctgcggga taggcgtcgc tccgggcgag
    11281 acaggcgcgc agcacatggg cgaagaccag ttgggagagg tattcggcca cgccgttcgc
    11341 accggggcgg tcggcactca tctcccgcag gacctgttcg aggagccagc acagcgcggg
    11401 cgcctcctcg cccgtgcggg acaggtgaat caccgggggc agagcctgga gcaacaagtc
    11461 ctcgcccgcg gtgttcagtt cgaaatgagc gccgaccgac accacctcgg tgacgccctc
    11521 ctccccggca tgggcgaaga ggtggggcga ggcccggagc agcgccggcg cgtcctgcgg
    11581 cggcacggac ggatcggcgg ccagaacata ggacagccct ccgccgaagg ccaccacatc
    11641 cccctgctcc aggagcacgg gccgctcgcc gccgtcgacc atcagccggc tcgcgccgcg
    11701 cagcacggcg tggaccttga gcctgccggg ggccggaaac cgcagagccc agcttcctcc
    11761 ggcagtgagc ccccggacga gtacgcatct cgcgccggtc agtccgaggg tgtcggtcag
    11821 aggatcgggg acggtcgaaa ccagatacgg cggtgcgccc atgaaaggac tctcgcgcaa
    11881 gttatccgga ctgacaagca tgtaccgcag gtcacttttc cctgcatcct gattaagtca
    11941 caggccccgg tcggcaggcg acggaaagta tgaagagtcc aggtcttttc gtacgcgcgt
    12001 ccgacacgca cgaattcgaa tcagatcgtc tcggaattca ccggcaccag tgccacaggt
    12061 gcatgacttc gcagcccatc catcgacttc gcccagcgac gagaacgcgg tccgaccccg
    12121 gtacagaagg ccggcagcgc tggtgagtca ggggcacatc tcgctgtgcc cacggaaaga
    12181 cgcggcaaaa caactggaca tatgtcgtag atttcggcac cgtcatgaca tttcaaggga
    12241 ccggccgaca gattcgacat ctccagcagt ccggacggag ataagggtaa tgcacatgat
    12301 ggattgcgtc tttgtcatgc ccggtacggt ggctgccccg cgcgggggtg tcctgcgcga
    12361 tttccacaac cgctacgagt ccgtacgtga atcgctgtcg ctcatcgaca cggcggcccg
    12421 ggaaatgggg ctgcccgaca tcagttcccg gttgatcgag cacgacggga cgaccgaccg
    12481 gcgcggaccc gaggtgcagt acctggagat cttcgcggtc agcatcgcca cccaccacgt
    12541 cctgatcgcc gagggcgtcc ggcccgtcgc gatcgtcggc cagagcatcg gggagctgtg
    12601 ggcgctggcc gccgcgggac gcctgtccgt ggacgacgcc gcccgcctgg ccgtggcccg
    12661 gtcccgggcg ctgacccggc agaactgggg cgggaagatg ctcgcggtcg gtgtggacgg
    12721 ccgccgggcg gaatcgctcg ccgggctgat caaccatccc gacctcgtac tggcctgcga
    12781 gaacactcct cggcagagcg tcatcagcgg ccccgaaccg ttgatcgaac aagtggaacg
    12841 ggtcgccgac gcgctcggct ggcccagttt ccgcctggac gtcccgcatc cgacgcacac
    12901 tccggcgatg gcgcaggcct cgcgggacct gcgggcgacc gcgccgcggg tcgcctacgg
    12961 cgcggggcgc tggcgggtct gctccccctg gctgggccgg gacgtcggtg acgacgaccc
    13021 ggtcggcctg gtcgccgacg cactcaccgc ccgggtccgg atactgcgta cgatccgcga
    13081 cctgcacgcg gcgggcgccg acgtcttcgt ggagtgcggg gagtggcccg tcgtcaccaa
    13141 gttcgtcgag gcgtcggttc cgggcgtgcg gtgtgtcgtc ccgctgagcg gcagcgaccc
    13201 ggtcgcagcc gtacgcgagt tggtcaccgg ttccaccgac ggcggcccgt tcctcccgcg
    13261 tccgccggcc ccgtcgggca ccgagcgcgg tcccgccgtg cgggtgagcg cggccacggc
    13321 gtccgcgccg gttccggcgc tcctcaccgc cgctccgctc tccgggacca ccaacgtgtc
    13381 cgcgtccgcg ccctccatgt cgtacgtggc cacccgcccc gctccggccc ccgccactcc
    13441 ggcggctccg gaggcccctg cggctccggc ctcgaccccg gtcgctccgg tcgctccggt
    13501 cgccccgccg gcgtccgccg agtgggacta cgagaccgta ctggccgagt tgcggacgct
    13561 ctacggcgat ttcctgggct acccgccgga ccttctcggt gaggacgacg gcctggagtc
    13621 cgagctgggt gtggagtcgc tcaagcaagt cgccctgctc gggcgggtgt ccgaacggtt
    13681 cggcctgccc ggtctgcggg cgaactcctc cctgctgacc gtcggcaccc tgcgccggat
    13741 cgcggagagc gtggtacagg gccgggcgga ggccgccgcg cgatgaccac caccgaccat
    13801 ctgcggggca gagtcgccct cgtgaccggg gccgcgaaga gcctcggcgc ggacatcgtt
    13861 cgccgcctgg cggagggcgg agcccatgtg atcgtcaact acttccactc ggtcgaacag
    13921 gcggagtcgc tgcgggcgga gctggaacag gccggtcaca gctgcgagtt catccgcgcc
    13981 tcggtggcca agaccagcga gatcgaccgg atgttcgacc tggtccggga gcggcacggc
    14041 aggctggaca ttctgatcaa caacgcggcg ggcggcgcgt tcctgccgct gttcggcgtc
    14101 gacgacacct actggcagcg ggcgtggtcg accaacgtga tggcggctta ccactgttcg
    14161 cgccgggccg ccgagctgat ggccgggaga gagggagcga gcatcctctg cctgtccagc
    14221 gtcggggcgc accagccggt tccggggtac ggccccggcg gcgtgaccaa ggcggccctg
    14281 gagtcgctgg tccgctatct ggcgcttgag ctggtaggcc ggggcatccg ggtcaacacg
    14341 gtgctgctgg gctccgtcgc cagtgagatc gtcgtcaatc tcgatgcacc ggacgcggcg
    14401 ctcggcgacc ccgccgggac cagcgagctg atgcgccgta ccctctcgac gccggaggcg
    14461 gccaggttga tcgtgcacct cctgcacgag gacgccggct tcatcaccgg gcagacgatc
    14521 ttcgccgacg gcggaatcag tatcggcggg atgcagggca tgcggctgca cagcaggctg
    14581 gccgaccagg tcagccgtac gccccggacg agcacgaccg gaacgagtac gcccgtcggg
    14641 agcacccccg ccccgggaca gccggcggcc gtccgccccg caccagcacc ggcaccggca
    14701 ccggcgccgg cgcccgcacc ggcaccagca ccagcggcgt cgccccagcc ggaccgaaca
    14761 cccaagccgg agcccgagca cgagcccgag ccggagcccg agcccgagcc ggaccgctgg
    14821 aggtccagga agcccgagac ggaggcggag gcggaccccg gagccgtcgc ggtggtgggc
    14881 ctcggcctga ccctgcccgg cgcgaacaac acggcggagt tctgggaccg gctgcgcgaa
    14941 ggcgtgctgc tctccagcga accgtccgcc ttcgagctga agcacttctg ggcgccgacc
    15001 cgggaggaga ccgacgcctt ctacgtccgc gaggccggct acctccacga cttcgtcccc
    15061 gatcccgcct cggtcgcgga accggacggg aacgtcggcc accccggctg gccccggacc
    15121 actcgctggc tgcggcactg cgccgtccag gccctggcag gggtgggccg ggccccgaag
    15181 gaccggtatc tcgctgtgac caccggcatc cacgaccaga cgggcctcgg agcccagggc
    15241 gtggtactgg gcgacgagta ccggcgcatg gtgcgcgggg cgatccccgc cgaccgggac
    15301 ggcgactggc tggccgagct ggccgatcac gcgatcagcg cgcactacgg cggcgacggc
    15361 gggaacccgc agggctacct gcccgcgtcc gtctcccgcg acgcgctgcg cgggctggtc
    15421 cccgacgact cgcagcacct gactctcgac tcggcctgtg ccagtgggct gttcgccgtc
    15481 gacgcggcgg tcaaggcact gcgcgagggc tcctgcgacg tggcgctggc cggcgggacc
    15541 gcggtggtcg agccgatcgg gttcacgctc ttctgccggg cccagggcat ttcgatgagc
    15601 ggccgggtgc gcccgttcga ccgggccgcc gacgggaccc tcatcggcga gggcgccgtc
    15661 atgctcgtac tgaagtcgta cgcgcgggcg gtggccgacg gtgaccgggt gctcggtgtc
    15721 atccggggca ccggtctcgc cgccgacggc cgggggaagg gcattcacgc tccggcccca
    15781 cgcgggcagg agctggcgat cgcccgcgcc tgggccgacg cgggcgtcga ggccgacgac
    15841 gtggactgga tcgtggcgca cggcaccggc actccggtcg gcgacgagat cgaactgcgc
    15901 tcgctgctct cccggctggg gcctcggcgg aaggcgtgcc tgctgacgtc gaacaagcag
    15961 gtcttcgggc acaccggcgt cctggcgggc ctggtctcgg tcgcgcacgc gctggtcgcc
    16021 ctcgaacgcc gtgcggtccc cggtcagccc gtggtcaccg atccgcaccc gctgctcggc
    16081 gacggctcgc gactgaccgt accggtcgag gacaggccct ggccggcgga cgggacacgg
    16141 ccgcgcgttg tgggggtgtc gtcgttcggc ctcggcggag cggacgcgca cgtggtcctc
    16201 tccgaccggg tgccgccggc cgcccccgcc ggcaggcggg gcggtgccgc gaccgccgac
    16261 gcggaggacc tggtcgtcgt cggctggaac gcccatctgc ccggcctggc gtccgaccgg
    16321 gtgcccgcct ggctgagcgg tgacggcccg cgcccggaag ccggcttcgg tacgccgtac
    16381 cctctgccgt cgccccgcga cgtgcgcatc ccgccgctga cgatgcggca catggacgcc
    16441 gcccacctga tgatgctcca ggtcctcggc cccctcctgg agcagctcgg cgagccgggc
    16501 gcgggcctgc ggcccaccac ggcgatcgtg gtgggatcga cgctgccgac cacgcacaac
    16561 acccgggccg cgctgcgggt gcacgcccgc gagtgcgcca cggcgttcga catcctgccc
    16621 gatccgaagc aggcgcaggc gttgaagacc tacctcgcga aggggatgga ggacgcccgg
    16681 gaggtgatcc ccggcgacct gaacgaggac gacttcaccg gagcggtctc ctgcatcctg
    16741 tcgggccggg ccgccaacta ctacgacttc caggccctgg ggaccagtgt ctactcccac
    16801 cgggactccg cgcacaccgc tgtcgacctg gcgctgcgtc agctcagaca ccgggcgtgc
    16861 gacctcgcgc tcgtcggcgc ggtgtgcctg cggccgatca gcggctggga ccgccatctc
    16921 acgggtctgg tgccggaggg ccggtccatc gcggaaggcg cggccgtcct ggcggtcacc
    16981 cggctctcca ccgcgctgga gcacggcctg cccgtcctgg gcgcgctctc gacggcggtc
    17041 gggggttcgg gcccggagga atcagcgacg cccgcgcact cccttcccgc gctggcggac
    17101 gccggacaca cctatctgtc gctggacgcc ctgctcacgg tcgtccgggc cgtcgtcacc
    17161 ggaacggacg ccctcgtgac gcccgccgcc gccggctcac cgctcatccg gttcaccccg
    17221 gcggccgaac cgccccggcc cggcccggcc cggcaggcac cggaacaggt cgccgcgccg
    17281 gaacaggccg cgccggagca agcacggccg gagcacacag cggccgaccg cgccgccggg
    17341 ccggagcagg ccgccgcgcc ggaacaggcc gcgccggagc aggccgccgc gcctgagcag
    17401 gccgcgccgg aggaccggtc cgcacccgag cacgacgagg gcttcaccgg tcgtcgtcag
    17461 accttccggc tcgtccccac cacgcctccg agcaggaatc ccgccgcacc ggccctcccg
    17521 ccgggcaccg tcgtcatcac cgacgccccg gatctcgccg cggcggtcgc cggcccggac
    17581 atcgccctct ggtcgcctcg gccgggagtc gccggcacga cccacgtgcc gccggaggag
    17641 gctcccgggg cactcgccgg cctgcccttc gtcccgcgcc atatccgggt cctgtcccgg
    17701 ctgcccgacc ttcacgccgg cggccacggg ggcgacgagg ccgaggccgc ccgggtggag
    17761 gacctccagg acctcacgtt caccgcactc caggcggcgc tgcccgcact gcgcagcggc
    17821 ggctcgctca gcgcggtcct gctcgggccg gtgccggacg acctcccgcc gccgctgagc
    17881 gccctgttca ccggcctggt ccgttccgta cgggccgagg tcccgcagtg cggcggggtg
    17941 acgctgctca gcgacgcacc ggacgcggcg agggccctgg accagttggc gcgtgccggc
    18001 accgcccagg tgcccgcaca cacgctggcc tgccgcgggg gcgactggtt cgcgctggcc
    18061 gtcgccgacg atcccgcgcc gccgcccccg gcgggagccg cctcgctgcc gcccggcgcg
    18121 gtcgtggtcg ccttcggcgg cgcccggggc atcaccccgg aactcctcca cgcggtcgcc
    18181 cgcaccagcg accggcccca cgtctacgtc atcggccgca ccccgttgcc ggagagcggc
    18241 gaaccgctgc cgccgcaggc cgagttcatc gccgccgggc ggcgcgcacg ccccggcgcg
    18301 tcggtgcgcg agctgcgggc cgactacgag aaggcccagg cccgcctgga ggtacgccgt
    18361 acggtccaca ggctgacgga gctgtgcggc ccggaccggg tccaccaccg ggtgtgcgac
    18421 gtcctcgacg ccgagcgcac caccgccgtc ctgggcgagg tcctggaccg gcacggtcgg
    18481 atcgacctgc tcatcaacac cgtcctcgac ctgcggtccc gtgcgctgca cgccaagacc
    18541 ctgaccgact tccgggcggt ccgggccacc aaggcgaccg gataccgcaa cctcaaacgg
    18601 gccctcgccg agcgtccgcc ccggatctgg tgcaacttca gcacgctggc gacgctcgcc
    18661 cccgcgcccg gcgacgtcga ctactgcgcc gtcaacgagt acctggcgta cgcgagcgcc
    18721 tgggcgcaga ggcacggacc ggacggccgg cacgagttcg cgatcctctg gagcgggtgg
    18781 cgggaggtcg gcgtcgccag cagcaccacc atgcgggaaa ccctcaaacg caaccggatg
    18841 gacgcctaca tcagcaccgc gcagggatgc gcgcagttcc tctccgccct cgcccggccg
    18901 ccggccggcg gggtctcctt cttcatccgg gacgaggagc gcgtcctgct ggcccggcgc
    18961 gggatcagca cctggggcac ctccggcggc ctcccggccc cggtcccggc cccggacgcg
    19021 ccaccgcccg ccccaccgga cccggcgctg accacaccgc tgctggacgg cgtcctgcac
    19081 cgcggcaagg actgggccgt cttcaccaag acctgggacc cgcgcaccct ggtcgagctg
    19141 gacggccggt ggatgcgcca ccaccgggtc aacggcgagt acacgctgcc cggtacgttc
    19201 accctggaag ccgcggccgg cgccgccgcg gccctctgcc cgggtctgcg ggtcaccggg
    19261 ttccgcgggc tcgtctgccg gacctccgtg acggtcaggc tcgccgggcc gccgcgcacc
    19321 gtcgcggtgg aggcccgcgt cacgagccgc cggccaggcg gcgccgaggt ggcggtcagg
    19381 atgacggcgc accggatcgg caagaacggc aaggtgctgc gcttcaacga cctgctgtgc
    19441 gagacgacgg tggtgctggc ggaccgctat cccgacctcg ccgggccgcc ggactgctcg
    19501 tcgtacgaac ccgaacccga tttcgcgatg ccggtctact cccccgaccc gccgatctcg
    19561 ctcaccggcc cgttcgccgg cacccgcgac tacgcccgcg ggccggacgg gtgcagcgcc
    19621 gggttcgctc tggaccacgc cgcctgggct ccggccctcg ccggggcggc cgtaccggcg
    19681 atcctgctgg acgcgatggt gcacctgctg ctgctgccgc cgcgcggtga ccgcccgccg
    19741 ctggtcggcc cgatggccgg gctcgacgag gtcgacctcg gggggccggg caacgactgc
    19801 cggctcagcg cggagaaccc ggtgatccgg ctgcactgcg acttcgccag cggggccctg
    19861 accgccgtga cgggtcgcgg acgggtgctg gcccggatca ccggcgtcag cgcccatgcc
    19921 ctggaccaca gcggagacgt ggtccggccc cgcggcggcg ttccgcagcc gcccccttcg
    19981 tgacagccga ggagacagca gtgttgtggc agaacatcgc gatcgccggg accggcgcgt
    20041 gggtaccacc cgtcagaccc gagcacggac cgtggaacgg agcggccacc gcgcagccgt
    20101 cgctggcggc gctcaacgga ttcgcctcgg ccgccgtctc cacggacagc acggcgacgc
    20161 agatggcggc ccgcgccggg ctcaaggcgc tgcgccacgc gggcgtcacg ggcgacgacc
    20221 tgagtctgct ggtgcacgcc aacttccagg acgaggacca ctacacgccc gcgccgtacc
    20281 tgctgcgggt gctcggaggg gcggacacca acgggatcga gctcggcgcg gccagtgacg
    20341 gcggggccgc cgcgctcgtc gtcgcggccg aacacctcac cgcccgaccg gacgcgaagg
    20401 ccgcgctggt cacggccgcg ggccggttcc cgcacgagcg gtggggccat tcccgggaac
    20461 tgggctacgt ggccggtgac gccggggccg ccgccgtact cacccggacg ccgggcttcg
    20521 cccgcctggc ggcgaccgcc cacgccaccg agccgcaact ggagactttg acccgggtca
    20581 ggaaggggcc cgccggcgcc gaacggtcct tcctcatcga ggagaccggg ttcatgcccc
    20641 acatcgacgc gatgcagcgc tccacgcgcc gctgcatcga gaccgtcctc gacgagaccg
    20701 ccgtgcgacc gcgggacatc acgcacgtgg tgtccatcgc gatcggtgcc gtcgtgctcg
    20761 acctggtgct cgccgggtca ccgctcggcg tccgggccgg cgacaccgcc tggaccttcg
    20821 gccggcacct cggccacgca ggtccgtgcg acatcctgct cgccctcgac cggatgttcc
    20881 gctccggcag gctgcgggcc ggcgaacgcg ttctcgtcgt gagtttcgga gtcggcttcc
    20941 gctggaccac cgcactgctg gaggtctccg gcaatcccgc cgcgacgccg gccggccgct
    21001 cagagaaaga atgaggttgt ccatgacaga cacgcgtacg gcgaccgccg cgtcggttcc
    21061 tctcgccccg cgggcgctgc cgctgctggg ccacgcactg cccctgctcc gcgatccgct
    21121 ggcgttcatc atgtccctgt ccgagtaccg cacgatggtc cgcgtccggc tgggcccgcg
    21181 ttccgccgtg atggtctgcg atccggcgct gacccggcag gtgttcctga acgaccgcgt
    21241 cttcgacaag ggcggcccga tctacgaccg gatcagcgag gtcatcggcg acggcctctc
    21301 cacctgctcg tacaccttgc accggcggca acggcggctc tgccagccgt cgttccaccc
    21361 cgccagactg gccgggtacg gggtggtgtt cgcccgggcc gccgagctga aggcggggtc
    21421 ctggcacgac ggcgacgtcc tcgacgtcac ccaggagatg atgacgctga cgacgcgggc
    21481 caccatggag acgatgttca gcggcgcgct cccggcggag accatgcggc ggtccctggc
    21541 cgacaccgcc accatcgtga gcgcgttctt ccgccggatg atgaccccgc ccctgctgcg
    21601 cagcctgccg actccgcgga agcggcgcta cgacgacgcc cgcgagcggc tgtcggccac
    21661 catcgcggag atcatcgccg aacggcgggc cgatccgacc gaccacgccg atctgctctc
    21721 cgccctggtc ggcgcggtcg acgaggagag cgaggacggc aggaagcagc tgaacgacac
    21781 cgaactcgcg gacgaggccc tgacgttctt cctcggcggg atggagacca cggccatcac
    21841 cctggcctgg gcgctgaacc tgctcgccac gcacccggac gtccagcgcc gcctccaggc
    21901 cgagaccgac ggcgtgctgg ccggcgggaa gctcgctccc gcgcacctgc ccgcgctcgg
    21961 cctggccacc cgggtggtga ccgaggcgct gcggctgtac ccgcccgcct ggatgatgac
    22021 ccgcaccctc cgggaggacg ccgaactcgg cggcgtacgg ctcaagcgcg gcagcgtcct
    22081 ggtgctcagc ccgtacctcc tgcaccggcg gcccgacctc tatccggagc cggaccggtt
    22141 cgacccggac cgctggctcg gcgcccagcc cgaccgggcc gcctacatcc cgttcggcgc
    22201 gggaccccgc aagtgcatcg gggaccagtt cgccctcaac gaggcggtcc tggccctcac
    22261 cgccgtcgtc gcgcgctggg aggtgtcccc cgtcggcgac gagccgttcc ggcccaaggt
    22321 ggagaccagt ctgagttcgc gcgggctggc cctgcggatc ggtgagcggc ggccggccct
    22381 cgccgacgcc gccgggctcc gcccggcggc cgtgccgacg cccgcgcccg ccgggccgcc
    22441 cgacgggccc ggcgacgtct gcccggtgac gcgcggggag cggtgacgcc gtgaagcccc
    22501 atctgaaacc gctggtgaag cagctcctcg gcgaccggcg ggccggtctg ctcaccgcga
    22561 ccccggccga cgccctgcgc gctccctcgc ggccctatcc gaacgggtgg ttctgcctgg
    22621 ccttcagcga cgaggtgcgg ccaggatcgg tcaccacccg tccgctcgcg ggcgcggagg
    22681 tggtcctcta ccggacggcc gcgggcaggc tgcgggccgt ccggccccgg tgcccgcatc
    22741 tgggagcgca tctcggggtc ggcggaacgg tcgagggcga ggacatcgtc tgccccttcc
    22801 accagttcgc cttcgatccg gccggcgtct gcgtacgcac gggctacggc cagccgccgc
    22861 cgaaggcgtc gctggcgcag tacccggtgt gcgaggccaa cggctcggtc tacgtgtggt
    22921 ggcacgcgct cggcctgccc ccgcggtggg aggtcccggc cctccccctg gacgaccggc
    22981 agcccttcag ccatgacacc ttcgacatcg ccggtcaccc gcaggacgtc atcgagaacg
    23041 cgttcgactg ggggcatctg cccaccctgc acggtctgaa gggcctcgac atcgagggcg
    23101 cgccggtggc cggggagccg gtcagcacgg tcaccgcgac ggcccggggc accgtcatgc
    23161 gcgggttccg ccagtcctac tcgctcacgg tgatcggact ggccaccatc gcggcgagga
    23221 cggtcctgcc ccggggggcg ggcagcctct acgtgatgct ccacgcgacc gcgaccggtc
    23281 cgggacgcgt ccagctccgg ttcggtacga agcttgagct gagcggccct cccggcgtgc
    23341 cggagagggc ggggcgcgcg gcggtgatgc ccgtggcccg gctcctcagc gccgtcctcc
    23401 agagggtggc gagcgtcgac accggcgcgg acctgctgat gtggcaccac caggagcacg
    23461 tcgagcatcc gaagctcgcc aggggcgacg gtccgatcgg ccgctaccgg cagtgggcgc
    23521 agcagttcta cacggaaccc gcgggcggcc tcgcgccgcc ggggccgccc cgtgccgagg
    23581 cgcgccggtc ggaggagtga gggccgacgg cggcgttccg gggcgctccc gccgcccggt
    23641 cgtcggcgat caccgtgcgt cggggcagcc cgcgagccgg ccgggccggg accgaaggag
    23701 ggacgatatg gcagcggaga acggcgttcc cggcacgggg caccgactgg ccgtgctggg
    23761 cgcgggggtg atgggttcgg gcatcgcggc gctggcggtc gggcacggaa tcgcggtgtg
    23821 gctgatcgac ctggaccggc gtcggctgga cgaggctccg gcgaggatcg gccaccaggt
    23881 gcgtacggcg cggctgctgg gcgcgctgcc ggacggggcc gtccccggcg cgctcgtcac
    23941 cggcctgtcg ctcgccggcc tgatggcagc cggtgacgcg gtccccaccg cggtgatcga
    24001 ggcggtcacc gagcatcccg acgccaaggc gaaggtcctc gcggaggtgt gcgccctggt
    24061 cccgccgggc accccgatca tctcgaacac gtcggcgatt cccgtggacg agctggcgct
    24121 ggcgacgacc cggccggcgg atctggtcgg cgcgcacttc atgaatccgc cctgtctgat
    24181 ccgtacggtc gaggtcatcc ggggtacgca gaccggcgag gccgccctgg cggcgctgcg
    24241 ggcgctgctc gccgtgctgc ggcggcaggc gatcgtggtc gaggacgcgc cgggtttcgt
    24301 gaccagtcgg atcctgcacc cgatgatcaa cgacgcggtc cgggtggtgg cgtcgggtac
    24361 cgcgagcgcc gacgcggtcg accgcctgat gcaggggtgc ctcggtcacc cgacggggcc
    24421 gctccgcacc gccgatctca tcgggctgga caacctggtc gactcgctgt gggtgctgca
    24481 cggccggacc ggtgacgagg gctgccgccc ctgcgacctg ctgctggaga tggtgcgggc
    24541 aggccgcctc ggccgcaaga gcgggcgcgg cttctacgag tacgagggag aacccgcatg
    24601 accacatcat ccgaccatcc ggtgccggaa cccgtcgtgg gcacgggcga cgtccaggcg
    24661 gacctgctgc ggttcctggc gcggcgtacg gggagggcct ggccgcccga cgcggacgtc
    24721 ttcgggtccg gtgggctgtc ctcgctcttc gccatggaga tggtggtgca tctggagagg
    24781 acgtacggca tcgccatccg cggcgccgac ctgcggatgg acaacttccg caccgtggcg
    24841 cggatggccg ggctggtcga acggctccgc gggccgggcc ccggcggctc cggtgcgtga
    24901 agccgtcgcg gcggcggcct cggcggtcac cgaactcgtc ggcgaccggg cgtccggctg
    24961 ggaccgggcg ggccggctgc ccgaggacgc ggtgcgcggg ctcggtgcgg ccgggctgct
    25021 cagcgctcag atcccggcga gccacggcgg gccggggtgg agcagcgcgg acagcggcga
    25081 gttcaccgcg cgggtgggca gtctgtgcag ctcgctgcgg agcgtcatga cctcgcaggg
    25141 catggccgcg tggaccgtcg aacggctcgg cgacccgggg caggcggcgg atctgctgcc
    25201 acggctggcc tcgggcgcga cggcggccgt ggccttcagc gaaccgcgcg cgggcagcga
    25261 cctgtcggcc atcgcgacca ccgtcaccgt cgacggggac gccctggtgc tcaacggacg
    25321 gaagacgtgg gtgaccgccg ccgactacgc cgatctcttc ctggtcgcgg cccggatgga
    25381 cgagggcggc gccatggtgg tggtggaccg gaccgccccc ggggtccggg tgcggcgggt
    25441 ggccgatccg ctgggctgcc gggcggccgg gcacgcggaa gtccgtttcg acgacgtgcg
    25501 gttgccgctc ggcagcctgt tggggggcgg gcggcagccg ctgtccctgc tcgtgacgac
    25561 ggccctggcc tacggccgga tctccgtcgc ctggggttgc gtcggcatcc tgcgggcctg
    25621 cgtggcggcg gccgtcggcc atgccgggtc ccggcggcag ttcggccggc cgctggggcg
    25681 gcaccagctc gtcgcccggc acctggccga cctgtggacc gcggagcagg tcgccacccg
    25741 ggcctgcgag tacgccagtc gctgctggga cgagaacgcc gcagagctgg gcacggccgt
    25801 cgtgctggcg aagtacgtca gcgcccggca cgcggccgag ggcgccgcca ccgcggtcca
    25861 ggtgctcgcc tcggccgggg cgcgggacgg tcacgtcgtc gcgcgggcgt accgcgacgc
    25921 caagctcatg gagatcatcg agggcagtaa cgagatgtgc cagttgatcc tggccgagca
    25981 ggcgctcggc cggtgctgac cccgcccggg gccgccggag aagccgtcgt cagtcgtcag
    26041 ccgtcagccg tcagccgtca gccgtcagcc gtcagccgtc acagggagcc gaacatgagc
    26101 gacaccgccc cggcggtccc gcccgcgacc gtgaagtgcc tggtctggga cctcgacaac
    26161 acgctctggc gcggcacgct gctggaggac gaggacgtcg tcctcaccga agcgatccgc
    26221 gcggtcgtca ccagcctgga cgcgcggggc atcctccagt cggtatgcag ccgcaacgac
    26281 cacgaccacg cctgggcacg gctggaggcg ctcggcatcg ccgaccactt cgtcctcccg
    26341 gagatcggct ggggccccaa gtcggctgcc gtgcgccgga tcagcgaacg gttgggcttc
    26401 gcccccggca cgatcgcctt catcgacgac cagccggccg agcgcgccga ggtcgcccac
    26461 catctgccgg acgtgcgctg ctacccggcc gaggccgcgg cgacgctgcc cggcctgccc
    26521 gagttcagcc cccggacggt gaccgccgac tcgcggcagc gccggaggat gtaccagtcc
    26581 ggcttccggc gggcggacga gcgggcgctc ttcaccggct cgcacgagga cttcctccgg
    26641 tcgctggaca tggtgctgag catcgggcgg gccacggagg aggccctgtc gcgggtcgag
    26701 gaactgaccc tgcgcaccag tcagatgaac gcgaccgggg tgcactaccc gatcgaggcg
    26761 ctgcgcaccc tcatcgccca accctcccac gaggtcctgg tcgcgacgct ctccgaccgc
    26821 ttcgggccgc acggtgccgt gggggtgaca ctgctccgga agcacccgga ggcatggcac
    26881 ctccggctgc tcgccacctc gtgccgagtg gtggcgtacg gggtggggac ggtcatcctc
    26941 aactggctgg tcgaccaggc cgcacgggcc ggcgtccacc tggtggcgga cttccgtgcc
    27001 accgaccgca accggatgat ggagatcgcc taccgtttcg ccggcttcga cgaacggccc
    27061 tgccgctgtc gggaccggat ctcgggggat tccggcgagg acgtccaact gctgcacctc
    27121 gtcgccgagc ggcggagcgc gcccgcggtg gtccggctga tcgctccgga actcaccgac
    27181 cgggcgccgg gccgcgcggg cgtcacctcc ggcggaccag agtgatgccg tcggccaccg
    27241 ggagcatgca gacgtcgacc cgcggatcgt cccggatcct ggcgttgacc tcgcggatac
    27301 cggcggtgtc cgcgtcctgg gcagcggggt cgatgacccg tccggcgagc agcgtgttgt
    27361 ccagcaccag cagcccgccc ggccgcacga gccgcagcgc cagctcgtag taccggggat
    27421 aattcgcctt gtcggcatcg atgaaaacga gaccgaaact cccgagacgg ccctcggcga
    27481 gcaattcctc cagcgtgtcg accgccgcac cgacgcgaac gtcgatgcgc tcccgcacac
    27541 gcgccctccg ccagaaatcg gcggcgatct cggtccaccg ctcgctcacc tcacaggtga
    27601 ccaagctccc ctgcggcgga agggcgcgag ccatgcacag cgtgctgtag ccggtgaacg
    27661 taccgatttc cagaacgtcc ctgacaccgg tcgccgcgac cagaaaagcg aggaactggc
    27721 cctcctcggc catcacctgc tgggattccc caccgggcaa ctcggcggtc gaacggcgca
    27781 gttcgcacag gatctcgtcc tctctgagcg agaactccct gacgtatcgc agaagctccg
    27841 gaccgatcga ggtctgttgt gccatggcga gaactccaga tgctccaaga aattcaccgg
    27901 tccaggcgcg gtgtcgagcc gaactccccg gcaaagggct ccctactccg cgatcttcgt
    27961 gctgtagtcg aaccggaaga ccggcaccgt cctgccctcc acctgctccg tctcaccggt
    28021 gcgcacgaag cgctgatgcc ttccgtagaa ggccacgatg agccgtgagg catcggcgac
    28081 gcaccccacc ggcagccgtt gcacacgcgg gagttccggc ggcccgccgc tcagcaccac
    28141 cagccgcccg gccctcgcct catcctcacc gatcacgccc accccgcctc tcgccactgg
    28201 agcaataccc attcgcttgt tctcattggg catgatcaga aagttattca ccaggcgtac
    28261 gggcagggcg ctcgtcgtgt tccccattcg acgcggaaca ccgcacgccc ccgaattccc
    28321 gtatcaccgt gatgcacatg cgccggagga cgggtgccga tcgaaaaatg acgcagatcc
    28381 tcagctcggc attccggccc ggccgccggc tgcccgcccg gaacgccgta gccaccggcc
    28441 tgtcgtcgcc gcgtgagaaa tcggtgagaa ggggcacaac cgggaacgtc ccggaccgcg
    28501 ccgctcgtcc ctccagcggg atgaacaaga caatcaggcg cgcttcggcc ttctgcctgc
    28561 tcctggtcct cgccctgctg gtacgggcga cctgggtgca ggcgtacgag gcacgggcgc
    28621 tcgcagacaa cgagcacaac cggcggaaca ccatcgcgca gtacgcgcag ccgctcggtg
    28681 acatcatcgt ggccggttca ccggtcaccg gatcgaagga gaccagcggc ggcgacctcc
    28741 gccacaagcg cacctacacg cagggcgagc tctacgcggc ggtgacgggc tacagctcgc
    28801 aggcgtacgg ggcgacccag ctcgaaggga tctacggcga cgtactggac ggcacggaca
    28861 gtcggctgaa gaacccggcg gatctgctca ccggggcaca ggcggccccg ggcgacgtgg
    28921 tgacgaccat cgacccggac gtgcagaagg cggcgtacga ggcgctcggc gacgacaagg
    28981 gcgcggcggt ggccatcgac ccgaagaccg ggcggatcct ggccatggtc tccaccccgt
    29041 cctacgaccc gtcggcgatc agcggtacgg cggacggcga cgcctggcag gccctgctgg
    29101 ccgaccggga caagccgctg acgaaccggg cgctgcggca gccgctggcg ccgggctcga
    29161 cgttcaagct cgtcgtggcg gcggcggcgc tggagaacgg gctgtacgga tcggtcgacg
    29221 aggccaccga cagccccgac ccgtacacgc tgcccggcac ccgcacggtg ctgcgcaacg
    29281 agaacgcctc cgccccgtgc gagaacgcca cgctgcgcac cgccctccag tactcgtgca
    29341 acaacgtctt cgcgaaggcc gccgccgacc tcgggcagga caaggtcaag gagatggcgg
    29401 acgccttcgg gttcggcacg gagaagctgg acgtcccggt gcgggccgcc gagagcgtct
    29461 atccgaccgg tatggacgcg gcgcagacgg cgctgacggg catcggccag ttcgaggtca
    29521 ccgccacccc gctccagatg gcgatggtca cctcggccct cgccaacggc ggcgagctgg
    29581 ccgcgccgca catggtctcc gaggtgaccg acggcggcgg ctccacgctg gaggagaccg
    29641 ctgacggcgc gtcgaagcgc gtggtgaagg agtcgaccgc ggagcagttg cgcagcgcga
    29701 tggtcacggt ggtcgaggag ggcaccggca cgaacgcccg gatcgccggg gccgaggtgg
    29761 gcggcaagac gggcaccgcg cagaacggcg tggacaacag caacaccccg tacgcctggt
    29821 tcacctcgta cgcgaaggac cgggcgagcg gcaaggaggt cgcggtcgcg gtgatcgtcg
    29881 aggactcggg gtcggcgcgc tccgaggtca gcggcaacgg cctggcggcg ccgatcgcgc
    29941 agaagacgat gcgggcggcg ctgggccggt gagccggggg cggaggcggg gcgacccgta
    30001 ccggtgggcg tacccgccgg gcccggccgg ccggccgccg gggtcggccg cccgcgtgac
    30061 gagtcggacg cctcctcagc cgctcgccgc cgcccccgcc cctgctcccg cgcccgcgcc
    30121 cgccgtgaac gggatctccg tgccgcggcg gtccgtcggg ggcggggccg ccgggtgtgc
    30181 ccagagtccc gccgcggcca gccggggcag gacgccctcg ccgaaccagt acgcctcctc
    30241 caggtgcggg tagccggaga gcacgaactc gtcgatgccc aggcggtggt actccgtgat
    30301 ccgttcggcg acctccgcgt ggccgccgac cagcgcggtg cccgccccgc cgcgtacgag
    30361 cccgatgccg gcccacaggt tggggtggat ctccagtccg tcccggccgc cgccgtgcag
    30421 ggccagcatc cgccgctgcc cctccgactc gctgcgggcc aggccctcct gcactccgcg
    30481 caccgtcgcc ccgtcgaagc cgtccagcag gcgggccgcc tcggcccacg ccgcgtccga
    30541 ggtgtcgcgc gtgatcacgt gcagccggat gccgaaccgc acggtacggc cctgctccgc
    30601 ggccaggcga cggatccagg cgatcttctc cgcgacctgg gccggcggct cgccccaggt
    30661 gaggtacacg tccgcgtggc gggccgcgac ggctccggcc gccggcgagg agccgccgaa
    30721 gtagatctcc ggtaccggat cgggcagccg ggtgagccgg gcctgctcga cccgcaggtg
    30781 ttcgccgtgc aggtcggtgg tcctcccgtc ccacagccgg cggacgatct ccaggaactc
    30841 cccggtgcgg gcgtagcggg cgtccttgtc gaggaagtcc ccgtacgcgc gctgctcgtg
    30901 gctctcgccg ccggtgacga cgttgagcag gagccgcccg ccggtctgcc gctggtaggt
    30961 ggaggccatc tgggcggcga gggtgggcga gacgaaaccc gggcggaagg ccacgaggaa
    31021 cttcagccgt tcggtgtgct ggctgaccat cgcggtggtg agccaggcgt cctcgcacca
    31081 ggccccggtc ggcgtgagca ctcccgtgaa gccggcgtcc tcggcggcgc gggcgatctg
    31141 cgcgaggtag cgcacggtcg gcggccggtc tccgcccgtc ggggtgaccg gggcgccgtg
    31201 gccgcctgcg acgacgtggc ggctgtcgcc gttggtgggc aggaaccagt ggaaggtcag
    31261 ggacatcgtc tctccgatgg tgcgggcggg gccggtgcgc cgccgccccg gatcaggcgg
    31321 gcggcggcgg gccggggtca gcgggcggcc ggcaccgggg cggtccggcc gagggccgcg
    31381 gcgaactggg cgacgacctg gtcgagcggc gcggcggacg ccgggtccag gacgacggtt
    31441 ccgtcgtcgt cggccgcgat gtgccggtcc aggacgaacc acccctggac gatgtgcgcg
    31501 gcgcccatcg aggagaggac cgggcgcagg gcgtagtcga gcgccaggac gtgggcggtg
    31561 gtgccgccgg tggcgagcgg caggacggtc ttgccggtga gcgcgtactg cggcaggagg
    31621 tccaggaacg acttgagcag cccggagtag gcggccttgt agaccggggt gccgatgacg
    31681 acgccgtcgg cgcgggcgac cagttcggcg gcccggacga tctcggggtg cgcgaagtcg
    31741 gcgccgagca gtgcctcggc ggggagcgtg cgcacgtcga gcggtatcac ctcgtggccc
    31801 tgggcggcca ggtcggcgtc gaggtggcgc aggaggcgtg cggtgcggga ggtggcggag
    31861 gggctgccgg agacggacag gacggtggcc atgggaactc atctctcagg ggcgtggcga
    31921 acggggcgcg tccccgtccc gcgcggcggg gcggggacgt gggcgggggt cgcggacgtg
    31981 ggtgggaagg gccggaggca gggtcgagcc gccccggtga tcgagaaacc cgatcagggg
    32041 ctggagacct cggcggccgg ggagagggcg gaagcctgac cggcttcccg cgtcacgggc
    32101 gcgacggcgg gcgggcgggc cgcgtcacga ggtgcgtcgc ctgccgtgcg cgagcggctc
    32161 gcggagcggc ggaaccgtac ggggacgggg cgcgggcaag cgcgaggaag ggtgctggtc
    32221 ctcagacttc gcggcaacag aaggcgctgg aaacgcggcc gaggtcgatg tggcggcggc
    32281 gggtcaggcg gcgcacatcc ctctcctttt cgcgctgcgg ggcacgcacc cggtacttcg
    32341 ggcgcggcgt cgacgtccag agtaggacgg ccgggcgctc cggtcgagaa ggcatcgacg
    32401 aaggagcgat agggtttccc ttccagagcc aggggcgagg ggcggggcgg ggcgtgcgga
    32461 tcgagcagct ggagtacatc gaggcggtca cccggctcgg gtcgctgcgc cgggcggcgg
    32521 aggaactgca cctgtcccag cccgcgttga gcgagaccgt acggaacctg gagcgcgagc
    32581 tgggcgtcac ggtgctggac cggaagcgtt cgggggcgac gatcagcgac gcggggcgcg
    32641 agctgctgcc gcacatcatc ggcgtgctgg acgcggtgga ccgcctgcgc cgggccgccg
    32701 acgaacagca ccgcaccagc cgcacggtcc gcctcggcac ggtgttcgcg gccaccgtgc
    32761 cgctgctggt accggcgatc cgcacgttcc acacgctgca ccccgccacc gaggtggagg
    32821 tcatcgcggc gcagcagtcg gccatccacc gctcgttgct ggagggcggc gtggatctcg
    32881 ggctggtgaa ctacctggag ggcgacgacc aggcccccga cctgcacacc acggaactgc
    32941 tgcgggggcg gccggtggtc tgcctgcgtc ccgacagtcc gctggcctcg cgggagtcgg
    33001 tcggggtgga ggatctgctg ggcgcgccgc tgatcgtgat gcgtgcgggc tatgtgatgc
    33061 accgcttcac tcaccggctg ctgaagggcc ggtcgccgtc cttctcgtat gcggcggacg
    33121 gggcggagat gggcaagctg atggtggcgg aggggctggg ggtgacgctg ctgccggact
    33181 acagcgtggt cggggatccg ctggagcgcg cgggggcgat cacctggcgg cctctggcgg
    33241 ccgacaccac caccgtgctc ctggtgctcc agcgcagccg ctccggctcg gtcacccggg
    33301 ccgcccgcga cctgcaccgg attctcgtgg agcgggccga ggcgcatcgc gcggacggct
    33361 gagcgggcgg accgaccgca accggcggag tccggcggga ggcgggccgg ctctcccggt
    33421 gacggcgcga agcccaccgc cgagcagggc gagccggccc cggacgaccc ggcccacgcc
    33481 tatgtgggcg ggcattgcgt gacggacccg cccgtatggc cgcacgggat gggccaaacg
    33541 gctgccacga gcgggaaggt aagggaacgg caaagcgggg tcgttcgtta ccccgtgcat
    33601 gaccgcaatg acccccggct cgaacatccc tctctccgtc gcccgcgtgg cggtggacgt
    33661 cgccgcaccg gtgcggctcg acgtctcggg cctgctgctc accgccgacg gcaaggtgcg
    33721 ctccgacgac gacttcatct tctacaacca gccctcgggt cccggcgtga cctaccgctc
    33781 cggcggcggt tcgtcgcccg acgcgatcgt ggtggacacc gccgccctcc cgcccggcat
    33841 cgagaagatc gtcgtcaccg ccagccctga cgccgaaggc cagaccttcc agggcgtcga
    33901 gcccaccgcc accgtgcgca acgccgacga cggcacggcg ctggccacct tcaccccgcc
    33961 ccggctgggc tccgagacgg cgctcgtggt catcgagatc tacctgcgca acggcgcgtg
    34021 gaaggcccgc gcggtcggcc agggctacgc gaacgggctg gccggcatcg ccacggactt
    34081 cggcgtcacg gtcgaggagc ccgccgctcc ggtcccggcc gccgctccgg ccgcccccgc
    34141 cgctccggcc gcccccgccg ctccggcggc cccgcggatc actccgccgg ctccggcctc
    34201 cgccgctccc ccggcgccgc ccgccgccgc gcccgccgct tcggggaaga tcaacctcga
    34261 caagggccgg gtcaacctcc agaagaacca gaccgtgtcg ctggtcaagg gcggggcccc
    34321 gctgctctca caggtcaaga tgggcctcgg ctgggagccc gcgttccggg gcaaggacat
    34381 cgacctggac gcctcggtca tcgcctacgg gcccaaccgc aaccacctgg acagctgcta
    34441 cttcggcaag ctcgccatcc tcaacggctc catcaagcac tccggcgaca acctcaccgg
    34501 cgagggcgcg ggcgacgacg aggtgatcgt cgtggacctg ggccgcatcc ccgccgaggc
    34561 gacgggcctc gtcttcacgg tcaactcgtt caccggccag aagttcaacg aggtcgccaa
    34621 ggcgtactgc cggctgatcg acgcggccac cggcgaggag ttggtccgct tcgacctgac
    34681 cggcgccgag ccgcagaccg gcgtcatgat ggcgaagctg atcaagcagt tcagcgggga
    34741 gtgggagatg acggcgatcg gggagttcgt gaagtcccgc accgtgcgcg gcatggtgaa
    34801 gcccgcctcg aaggccctct agacgccgtc cggcgtccgg cccccgcggg cggccggggg
    34861 cagcgacgga gtccggggcg cctgatcgat gtcaggcgcc ccggatccgg agagcatggg
    34921 cggcgcgctc gctcgtcgcg cccctcagag cttggtcagc ttggagtacg ggctcaggat
    34981 ccttccctgt cgccccgaga agtcgatcag gactgcgtcg ttgtcgccct cgacggcgag
    35041 gatgcgtccg agaccgaact ggtcgtgcga caccctgtcg cccacatcga agcattcgac
    35101 cggtggggcc tcctgggccg ggcggttgaa gggactggaa ggcaggtgac gccgggatcc
    35161 ggctgactgt ttcattacgt cgagtatgcg ccctgggaag gcccgacgcc atgcccgtca
    35221 gccgccccgg gcccagaagt gccggattcg taatccgccg ccgcaccggc cggtcagcgc
    35281 ttccaccggt ctccggcggc ggaaccgcgc ggaacgccgc gccggaaaga cccccgaacg
    35341 tgtggcgggc gctccccgca ccgccgctcc gcgctcccgc ttcgaggtcc tccggccccg
    35401 ccgctcccga cccctcgccg ctcccgaccc ctcgccgtcg ccgctcagtc cgccgcgcgc
    35461 gaccgcgcct tgaaggcggc cttgcgggcc tccttggcgg ccttcttgtc gccgtgcagc
    35521 cgtcccatgg cctccagcac gtcggcggtg gccgggtggt cgacacgcca gacctcgtcg
    35581 aagaagccgc tgtgctgcgc ggagagccct tcgatcaggc cctggagctc gtcgaggtcg
    35641 ccgtccgcgt cgagctgggc ggcgatggtg tcgatggcga gccagaagat catcgactcc
    35701 ggcgggacgg gcacgtcggc agcgccgcgc tccgcgagcc agacccgggc cagaccgccg
    35761 agctccgcgt ccccgagcac cgcgcgtacg gccggttcgg cctccgggcc ggcgagcgcg
    35821 agggcctgct ggcagttcag gcggcgcagc ggcgcgcccg cgtccgtacc gcgcgccgcc
    35881 gccagcagct cggccgcggc ggccacggag ccctccgccc cgaacccggc gagccagagc
    35941 ccgacctcgg cacgggccgc ggactccggg tagtgcgcga tgccgtcgag gagcgcgtcg
    36001 gcgcccttgc cggcgaggtc gccgacggcc ggcgcgtcca caccggcctc cagcatccgg
    36061 gcccggacgc cgtacaggcc gagcggggtg agcctgacca tgccgtaccg ggtgacgtcg
    36121 tcctcgtcgg aggcccccgc ggcgtcctcc tcgcccgcct ccaccatcaa cgactcgtcg
    36181 acgggctggt actcgatgat gccgatgggc tccagcagcc ggaactggtc gtcgaggcgc
    36241 atcatcgcct ccgacacctg ctccaggatg tcgtcggtcg gctcgcccat gtcgtcgggg
    36301 acgatcatcg aggcggcgag ggcgggcagc ggcaccgggc cgtcgcccgc gccgttgtcc
    36361 gcgagggtga gcaggtagag gttgccgagg acgccgtcga ggaactccgc ctccgcctcc
    36421 gggtcccagt ccagcgcgtc gaagtcgatc gaaccgtcct cgcccacgag gtcggcgaag
    36481 tcgtcgagga ccggtgcggt ggcgtcggcg tgcacggcgt cgaggccgtc gagccagatc
    36541 cccagcacgt cctgcgggga gccgccggtg agcagcgcca ggttctcgcc ctgcgtgacg
    36601 gtgccctcgg cctcgtccga gggctcgtcc tcctccgggt ccgtgacgtc gaggaggccg
    36661 gtgtccacgg ccagccgcca cgcctcgctc gcgtacgccg cgccgtcctc gtcggccggc
    36721 agtcccaggt gctccgcggc ggccggcagc tgcgcctcgg cgagctcgcc gccggccccg
    36781 acccgggtct cgggccccgc ccagcgggcc agccggaccg cgcggacgaa cagcggggcg
    36841 gccagcgcgt cccgtgccag ttcggcctcg gaggtcagcc gcaccggcgg cagggtcggg
    36901 cgctctgcgg acatcggggg ttctcctcgg tgcgtgctcg ggggcgtacg aggtgtgtac
    36961 gcgcttcagc cgcccaagcc tagacgcatt tcggcgcatg ccgcccggtt cgggcggggc
    37021 ggggacggcg ttctccggac aaccttgaca accgccgtac gggaccaggg gattgacgcg
    37081 tgtagaccgg gtcccggcac cgccggccgg tgcggtgcgg gcccgtgacc gccctcgcct
    37141 ctctcggagc ccgggacgcc cgcgccccgc cgggccgcgc ggtggccgac gggccgcgcg
    37201 gtggccgacg ggccgcggga cagtccttag ttgtgggcgt gcaggacgtc gttcaggccg
    37261 ccccagaccg cgttgttcgg gcgggcctcg acggtgccgg tgaccgagtt gcggcggaag
    37321 aggatgttgg aggcgccgga gagctcgcgg gccttcacga cctgtccgtc cggcagcgtg
    37381 acgcgggtac cggcggtgat gtacagcccg gcctccacga cgcactcgtc gccgagcgcg
    37441 atcccgacgc cggcctcggc gccgaccagg gagcgctcgc cgatcacgat gcgctccttg
    37501 ccgccgccgg agagcgtgcc catggtggag gcgccgccgc cgatgtcgga gccgtccccg
    37561 acgacgacgc cggcggagat gcggccctcg atcatggagg tgccgagcgt gcccgcgttg
    37621 aagttcacga agccctcgtg catgacggtc gtcccggccg cgaggtgcgc gccgagccgg
    37681 acccggtccg cgtcggcgat ccgcacgccc tgcggggcga cgtagtccgt catccgcggg
    37741 aacttgtcga ccgaggtcac ctggaggtgc agcccttcgg cgcgggcgtt caaccgcacc
    37801 cgctccaggt cgtcgaccgc gaccgggccg agcgaggtcc aggcgacgtt ggccaggtgg
    37861 gcgaagatgc cttccaggtt ctgaccgtgc ggcttcacca gccggtggga gagcaggtgg
    37921 agtcgcaggt agacgtcgtg cgcgtcgagc ggcttgtcgt ccagtgaggc gatgaccgtg
    37981 gagacggcga cgacctcgac gccgcgccgg gcgtccacac cgatggcctt ggcggctccc
    38041 tcgccgagcc ggttcacggc ctcgtccggg ccgaggcgct ccgtaccggc cgggccgggt
    38101 tcggaggtca gctcgggggc ggggaaccac gtgtcgagga cggtgccgtc accggcgatg
    38161 gtggccagtc cggcggcgac ggcgccggtg gtgcgggaag aaccctggga agtcgtgtcg
    38221 gtcatgaaca gcaacctaac cggcggcggc ccgcccgggc caaccggtct cagcctccgg
    38281 cctccggcga agcgcccgcc cgtgcgccgc cgggcgcggg gatgatcctc gccagcatct
    38341 cgcgggtgtg gccggcgtcg aaggcggagc cggtgagtag cgcccggagg cagatgccgt
    38401 ccatcagcgc gacgagcgcg cgtgcggtgg ccggatcggt gtgccgggac agtacgccga
    38461 cggccgcgtc ggcccactcg gcggcgaccg ggcgcagcgc gggtcggcgc agggccgcca
    38521 ggtacagctc gtactccagc tccgcggctc cggactcacc ggcgaaccac cgctccagca
    38581 gccgggtcag ctcatcggcg aggccggccg ggccgccgcc gtcctcgccg gacggttccg
    38641 ccgcgaggac ggggctctcc cggagggtcc gcgcgaagtt ctcgtcgagc cggcgcaggg
    38701 cggcgaccag cagttcgtcg agggagccga agtggtacgt ggtcgagccg aggggcacgt
    38761 cggcctcggc cgcgacggtg cggtggctga gtcccgccat cccgtgcgcc gcgaccacgc
    38821 gcagggcggc gtcgacgatg cgggtgcgcc ggtcggggtc gtaccgccgg gccatcagtg
    38881 cgcgccgccc aggttgagca cgaccacccc gacgatgatc agcgcgatgc ccgcgagctt
    38941 caccgcaccg gcggactccc cgaggaacag gatgccgatg gccgcgaccg cggcggtgcc
    39001 ggccccggcc cagatcgcgt acgcggtgcc cacggacagc gtcttgagcg tctgcgcgag
    39061 gagcgtgaag gcgatgacgt agccgaccac cgtggcgagc gagggccaca ggcgggtgaa
    39121 gccctcgctg tacttcatgg ccgtcgtccc ggccacctcc gccgcgatgg cgccggccag
    39181 cagtccgtat gcgtatccca tgggtgcgac ggtactcaac gttgcgtacg gccgtacata
    39241 tcatcggccc gcgtcgggag cgctacggtg tgccgaccga caacacggcc cggtacacgg
    39301 gccgacgaca cgacggagac gcagtggcgc aggatgcagg gtggggcggt ggcccgtacg
    39361 ggggcgcgcc tcacggcggg gggccgtatc ccgggggcgc gcccgggccc gcgggcggct
    39421 ggaacggtgg ctgggcggca ccgcccaaac cgggcgtgat acccctggcg ccgctgaggg
    39481 tctcggacat cctcagcggc gccttctcga cgctcgggcg gtactggaag ccgctgatcg
    39541 ggatggcgct gacgctgttc ggggcggcga cgctcgtgat ggccgtcgcg ctggtggtcg
    39601 ccgcgtccac cgtcgcgagc aagtgggacg aactgacgtc cggctccccg gacgcccccg
    39661 atgcggcgga actggtcccg ctgggcgtcg cgttcagcgt cctgatggtc ctcggcgtcg
    39721 ccgcctacct gctggcctcg gccgtggtgc aggcggcggt gcccgtggtc ctccaggagg
    39781 ccgtcctcgg ccgcccgatc cgcttcggcg ccgtctggag ccgggcgtgg tcgcgggcct
    39841 ggtccgtcat cggcaccgcg ctcgtgatgg ggctcgtcgc gatcatcccg atggcgttct
    39901 tcatgaccgc cttcgccggg ctgatggtct acctcgtatc gctgggcgac gagcacggcg
    39961 tcctgccgat gatgtggttc ggcctcctcg gcgcgctgct cgtcgccccg gcggcgacct
    40021 ggctctatgt gcggttcagc ctggccccga cgatcgtggt cttcgagaag cagcgcccgg
    40081 tcgcggccct gcgccgctcg gcccggctgg tgcgcgacag ctggtggcgg gtcttcggcg
    40141 tcgggctgct cgcgtacgcg atggccgccg tcatcgcgct catgatccag ggaccgttcc
    40201 agctggccgg cgcgctcccc ggcctgttcg aacgcgcgga cacgaccgcc gaacggagcg
    40261 gcggggagat gatcgccctg ttcggcggcc tgatgctgct gtcgctcgtc agccagctgg
    40321 tcgcccagct cttcacggcg atcttcccgc ccctgatggt cggcctgctc tacgtggacc
    40381 gccggatgcg caccgagaac ctgggcccaa tcctggccga ggcggcaggg cggacactgc
    40441 ccgagcagta cggcccgcca cccgcccaga gctgacgccg ggctcagccg gtcagcgtcc
    40501 gcttcgggcg gagcacacag aactcatcgc cctcggggtc gcccaacaca cggaaccgta
    40561 ttgccccgtt cgaccgcccc gccctcggcg cgtggctcgc ccgacccgag cggtacgacg
    40621 tgcttgtccg gtggcccttt gaccgtgcca tccggtccat gagcgacatg cacgaccttg
    40681 ccaagtgggc agagcagcaa cgaaagatgc tcgtcttcgc cgagggagtc ggcgggggca
    40741 agctcgtctc cgacttccgc aatccggttg acccgatggc cgagttcccc atgatgatgc
    40801 tcgcctttgc ggcacaagtg gaagcgcaga gcatcaagga ctgtgttacc ggcgctatcg
    40861 ctgccatccg gaaaatgccg cttcggtggc ggggtggcgg tcgtccgccg tacggctata
    40921 tgcccgcccc cgtgcccgcc gagttcggcg gtatcgggtg gacgctcgta ccagacctcg
    40981 gcgcggtgac gatcattgaa ggggtcgtcc gagg
//