LOCUS       NZ_ML123034            22214 bp    DNA     linear   CON 23-MAY-2024
DEFINITION  Streptomyces sp. ADI96-02 scaffold001, whole genome shotgun
            sequence.
ACCESSION   NZ_ML123034
VERSION     NZ_ML123034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. ADI96-02
  ORGANISM  Streptomyces sp. ADI96-02
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Streptomyces spp. from the marine sponge Antho dichothoma: analyses
            of secondary metabolite biosynthesis gene clusters and some of their
            products
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6907715)
  AUTHORS   Guerrero-Garzon,J.F., Zehl,M., Urban,E., Schneider,O., Ruckert,C.,
            Busche,T., Kalinowski,J. and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-NOV-2018) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 64.8x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003846185.1-RS_2024_05_23
            Annotation Date                   :: 05/23/2024 03:48:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,089
            CDSs (total)                      :: 6,032
            Genes (coding)                    :: 5,843
            CDSs (with protein)               :: 5,843
            Genes (RNA)                       :: 57
            tRNAs                             :: 54
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 189
            CDSs (without protein)            :: 189
            Pseudo Genes (ambiguous residues) :: 0 of 189
            Pseudo Genes (frameshifted)       :: 68 of 189
            Pseudo Genes (incomplete)         :: 155 of 189
            Pseudo Genes (internal stop)      :: 10 of 189
            Pseudo Genes (multiple problems)  :: 42 of 189
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:00:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 206058
            Orig. end                         :: 228272
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            ML123034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Zotchev Lab, Department of
            Pharmacognosy, University of Vienna.
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(785..1465)
                     /locus_tag="EES43_RS00880"
                     /old_locus_tag="EES43_00905"
     CDS             complement(785..1465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956429.1"
                     /locus_tag="EES43_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00905"
                     /product="VanZ family protein"
                     /protein_id="WP_124266847.1"
                     /transl_table=11
                     /translation="MTAEADSRQGQGTWARLLMRVAVLTVVLLGLVAFSVFLARVTLTP
                     SPASEDLVTSNLQPGRSLREYAEDYTFLAACKQAGGNLLLGVPFGLLLPFIVSRRLRMI
                     RLTLLTAVVMIVVELIQGALVVGRAFDVDDVILNTSGALLGYLLLGRRISHRYYVYADA
                     PRPEPVPTAAPEAEPKPETKPETKPEPARGNGAKTLTGKQAAGTSTGPAPGRAHTVLDR
                     FRRR"
     gene            1562..2062
                     /locus_tag="EES43_RS00885"
                     /old_locus_tag="EES43_00910"
     CDS             1562..2062
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038469.1"
                     /locus_tag="EES43_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00910"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_124266848.1"
                     /transl_table=11
                     /translation="MNAREKKDRLAEAERLRTGGRPEEARERLLALTTRFPDDAEVAYR
                     TACVHDVLGLETEAVPYYERSLAGAGLGAEDRRGALLGLGSTYRVLGRYGQSVETLRRG
                     VEEFPDDGALRTFLSMALFNIGEHDESMRLLLELVAATSDDEHVRRYRQAIAHYAKDLR
                     ATA"
     gene            2226..2888
                     /locus_tag="EES43_RS00890"
                     /old_locus_tag="EES43_00915"
     CDS             2226..2888
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524490.1"
                     /locus_tag="EES43_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00915"
                     /product="YoaK family protein"
                     /protein_id="WP_164493321.1"
                     /transl_table=11
                     /translation="MLLSAASGAADAFVFLCVGEVFAGVMTGNLVLLGASAAGAGENGV
                     ALKVVAALGAYAAGVAAGAVLAGRLGLRLRVLLRVETVLLGAAAVLWGLDLVPSYGDRI
                     GLLALVSVAMGVQARIGGTPTNYFTGTLTSLARRVAERELRAGDGWLTGRLVAVVAGAL
                     LAGLTQRWWSPGAAVGPVVLAACALALEEAGRRRPRRDTGKPRPDRGNPAGAAQGWP"
     gene            complement(3117..3377)
                     /locus_tag="EES43_RS00895"
                     /old_locus_tag="EES43_00920"
     CDS             complement(3117..3377)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606682.1"
                     /locus_tag="EES43_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00920"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_124266850.1"
                     /transl_table=11
                     /translation="MKPRIHPESRPVVFRDRVAGTSFLTRSTADSGERVTWEDGNTYPV
                     IDVETSSASHPFYTGGRQVLDTAGRVEKFRRRYGDGGTPES"
     gene            complement(3469..3633)
                     /gene="rpmG"
                     /locus_tag="EES43_RS00900"
                     /old_locus_tag="EES43_00925"
     CDS             complement(3469..3633)
                     /GO_component="GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpmG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470368.1"
                     /locus_tag="EES43_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00925"
                     /product="50S ribosomal protein L33"
                     /protein_id="WP_124266851.1"
                     /transl_table=11
                     /translation="MARSELRPIVTLRSTAGTGRSYVTRKNRRNTPDRLELRKFDSAAG
                     QHVLFRETR"
     misc_feature    3675..3690
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.05"
                     /tool="antismash"
     misc_feature    complement(3679..3690)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    3833..3844
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.29"
                     /tool="antismash"
     misc_feature    3962..3977
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.2"
                     /tool="antismash"
     gene            4133..5557
                     /locus_tag="EES43_RS00905"
                     /old_locus_tag="EES43_00930"
     CDS             4133..5557
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883986.1"
                     /locus_tag="EES43_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00930"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_124266852.1"
                     /transl_table=11
                     /translation="MPSHLFADRPAPQQPAHDAVDALIHRAHRLRGDVDAVRRDAVTDE
                     ENAQLRWQRALCELAVHHLDNLGAHLSQLRAGLPEQRSTGTAPDRRRAAAPLDASPPSR
                     VGSAEWNLLTDEVSWSKELYEILGRPRESEPLSLDEMPSVLLPEDQPLLTSMVTGCLVD
                     GRPMDGEFRIVRPDRRLRTVHMTGEPVLDAHGRTASMWAVLRDVSELRRGEEAVSRSQD
                     SVRHEEHIERTEHRMAVELQEAVLPPWRGSLRLPRQGPGALDIAAHYLPSRSSGLIGGD
                     WYDAMELPDGRTLLSVGDLAGHGIPATSAMAMLLGALRGMAVAGIEPGALMGHLNQLLE
                     SSIQPALGSALCCRFDPATGILSWSQAGHPAPLLFRDGTGRLLPPPDGVLLGAASEVAF
                     EQDEVRLLPGDVLVLHTDGLTRRSDRGAGPEALLGLAPRFARARTAQECVRSVVEEFGG
                     SERLDDACVLVARFGG"
     gene            complement(5698..7194)
                     /locus_tag="EES43_RS00910"
                     /old_locus_tag="EES43_00935"
     CDS             complement(5698..7194)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606686.1"
                     /locus_tag="EES43_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00935"
                     /product="hypothetical protein"
                     /protein_id="WP_124266853.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPGVLAALFTERLGRVVTIEDLGFGRRGRVGKRRDSGTEHHPDQL
                     PWAPKRTAAVLTEFTGMDLMLNRRGLVEAGAALAAGSAITGPMYDWLHSDPAATAGAPR
                     ANDSMNADPAGYDRYEAAPVGSEEIEALEHSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYHHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLARSGSGEENLPRTQAMLHTIEAWAQAAMGHGQA
                     MRRTLGEAEELFVSDRGDGPSPSWMQMFDEADLRGMQALAFRTLAEHDSSAAVIAQRHA
                     KEALELRVNGRQRSKIFDYISLASACFIADDPEQADRYARLALVSMGETSSHRTWDRLR
                     EMYRLTGRFSGNPGIQDLREEIERSLPQRPAAKKVPDQRT"
     gene            7426..8562
                     /locus_tag="EES43_RS00915"
                     /old_locus_tag="EES43_00940"
     CDS             7426..8562
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="EES43_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00940"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_124266854.1"
                     /sec_met_domain="APH (E-value: 3.5e-17, bitscore: 61.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPLGTGGGPYLAPHAGAPAQALGRTRRAAG
                     PGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGAAGRATAV
                     AKCLLDHSPAWTERFRHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRVAAL
                     TRHPAEAPPRADLRAALSAISRVNAWRPPPGLFEAPLDYASRISRYHELGLFTDRDLGD
                     LQKLLHGLAHAGGRGGMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLWA
                     VLGDAPVARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRSMREASSPGAG
                     QERPGALSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    7747..7749
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9141..9797
                     /locus_tag="EES43_RS00920"
                     /old_locus_tag="EES43_00945"
     CDS             9141..9797
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="EES43_RS00920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00945"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_124266855.1"
                     /transl_table=11
                     /translation="MPRLTTIRITRSHKLAAAVLVAAGSVTAVAATGGQSDARPVEARS
                     SVAVQPVAAAGVPTAKDAAKKAAEETAAKKAAATREATAEKDAAEKDRTEKQAANRSTE
                     RKAAPKQYKNNLDGWIRESLDIMEKKNIPGSYEGLHRNIMRESSGDPNAVNDWDINARN
                     GVPSKGLLQVIQPTFDAYHVSGTPKKLTDPVANITAAANYAADRYGSIDNVDSAY"
     misc_feature    9889..9905
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.79"
                     /tool="antismash"
     gene            10001..12214
                     /locus_tag="EES43_RS00925"
                     /old_locus_tag="EES43_00950"
     CDS             10001..12214
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956438.1"
                     /locus_tag="EES43_RS00925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00950"
                     /product="terpene synthase family protein"
                     /protein_id="WP_124266856.1"
                     /sec_met_domain="T1TS (E-value: 4.1e-86, bitscore: 288.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTRQWARGMGMLEGSGIW
                     EAADLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTHDREGGKRY
                     LDRLPAFMPMERGAPTPKPRNPVEAGLADLWARTVPAMSDAWRARFAEATENLLNESLW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYAAGAEVPASVADARPLRVLRDAFS
                     DGVHLRNDLFSYQREVEDEGENSNGVLVLERFLGCTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLCAEKGLGPAESTAVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGFG
                     MSAASIRFTTRAESARARSHTHVPYQHVGPSLLPDFELPFGTTLSPHLEGARSRLVDWS
                     RRMGILEAQPGVPGSHIWDEERLIAIDLPLCAAGLHPDATPDELDLSSGWLAWGTYGDD
                     WFPVVHGRTRDLAGARLANERLSLFMPLDGGGAPEPVNALERGLGDLWRRTAAPMDLSG
                     RRTFREAVESMTASWLWELANQAQNRIPDPVDYVEMRRATFGSDLTMSLCRLGHGRKVP
                     DAVYRSGPMRSLENAAADYACLLNDLFSYQKEIEYEGEVHNGVLVVQNFFAVDYPTGVA
                     IVHDLMKSRLRQFLHVAEVELPVLYDDFDLDAEAREVLAGYVLELKHWLAGILIWHRGC
                     RRYREEDLRRGHGTPWHISGPTGLGTSAAQVTRLMAQLAGSGV"
     gene            12496..13071
                     /locus_tag="EES43_RS00930"
                     /old_locus_tag="EES43_00955"
     CDS             12496..13071
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EES43_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EES43_00955"
                     /product="hypothetical protein"
                     /protein_id="WP_206429974.1"
                     /transl_table=11
                     /translation="MRVSARTSRQRLATSVLAVLLAVGTAACSGEAPDKPAADAPAAGD
                     TAGGTGGGDSTPDSGQDPGVVYAACMRDNGVEVDDPKPGERPQIPEGTPPRVLDKLEKV
                     CGELPGSGAMTGGLSSDVLKSPEVEALRLTYLTCMRKNGYEQPEPDANGNVSMQITPEY
                     TAAQKACTSENDALSKKIKELAKQGGAQ"
     gene            13068..14252
                     /locus_tag="EES43_RS00935"
                     /old_locus_tag="EES43_00960"
     CDS             13068..14252
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="EES43_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00960"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_124266858.1"
                     /transl_table=11
                     /translation="MREVVEPVEGAEEHGAGDDPAVTVGRTPGADGSGGRGRGRRGGGG
                     RGRRGLLVAVAVAVVAAAVGAGLLYGRTGTEREPASGEPLPPATEKAVRGDLVSEVRSF
                     GTLQFSGDRRVTNRIAGTFTWLPAASSVVERGERLYAVDDRPVVLMRGDLPAWREFRAR
                     MKDGKDVRMLEENLAALGYTDFTVDEEFSRKTEAALKRWQKNNGLPQSGKLELGRVVFA
                     PGDLRIKKSAVRAGDAAVPGGEVLRAGGSRQRVSTQVPLEAQELALEGASVEIELPDGD
                     RTDGTVASVGQQRLNEQGKKVVPVTVRLDSPGDVGKLPSADVTVVLRKVEAKNVYSVPV
                     TALLPLPDGGFAVQIVEGGQVRRVKVRTGAFADGRAEVSGPGITEGVRVGVPRL"
     gene            14312..15022
                     /locus_tag="EES43_RS00940"
                     /old_locus_tag="EES43_00965"
     CDS             14312..15022
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178148.1"
                     /locus_tag="EES43_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00965"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_206430155.1"
                     /transl_table=11
                     /translation="MVRLTGVGRSYGDGEHRVHALRDVTVDIGPGELLAVVGPSGSGKS
                     TLLHLVGTLDRPSHGQVLVDGHDVARLDDRGLSALRAHRIGFVFQHFHLAEGTRALDNV
                     ADGLLYTGMPRRRRRERAEAALRRVGLGHRLGHRSHQMSGGERQRVAIARAVVGEPALL
                     LADEPTGALDTHAGGLVVELLRELHRDGTTVVIITHDNELAAGLPRRLLMRDGRLVDDI
                     AAGPAVRLRNGDAT"
     gene            15019..16221
                     /locus_tag="EES43_RS00945"
                     /old_locus_tag="EES43_00970"
     CDS             15019..16221
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241103.1"
                     /locus_tag="EES43_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00970"
                     /product="ABC transporter permease"
                     /protein_id="WP_124266860.1"
                     /transl_table=11
                     /translation="MNRTHPLASRLRSGDLLRLGATGLRTRPLRAVLSAAGIAIGIAAM
                     IAVLGISASSQAHLDAELERLGTNLLTVAPGEDPDTGAPVPLPTTTVRTVARADGVDSV
                     SATGEITGVGAYRNARVHRAESNALSVLAVEGNLLATLRGTLAAGGWLDRAPAGYPTTV
                     LGHRAAQRLGVTGAGEQVWLGDRYFTVLGVVAPVPLAPELDTAVLVNRAAAETYLGFDG
                     RPTLVYERSADHLVESVRVLLPRAVDAENPQNVVVSRPSDALKARQAAEESFTGLLVGL
                     GGVALFVGGIGVANTMVITVIERRREIGLRRALGAARRHITRQFLVEALLLSTLGGLAG
                     AALGAGVTAGYALSRGWPTAIPLVAPVGGVAATMVIGALAGLYPALRAARTPPTVALAA
                     A"
     gene            16347..17012
                     /locus_tag="EES43_RS00950"
                     /old_locus_tag="EES43_00975"
     CDS             16347..17012
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959884.1"
                     /locus_tag="EES43_RS00950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00975"
                     /product="response regulator transcription factor"
                     /protein_id="WP_124266861.1"
                     /transl_table=11
                     /translation="MRVLIVEDEPYMAEALVAGLRREAMAVDLATDGASALDRLSCHDY
                     DVVVLDRDLPDVHGDEVCRRLTSARSPVRILMLTAAASLDDRVGGLRLGADDYLPKPFE
                     FPELVARLHALHRRAGTPPPPVLDCADVRLDPFRREAYRDGRYLRLTRKEFAVLHLLMA
                     AQGGVVSAETLLEKGWDENADPFTNAVRVTVSNLRRKLGSPPLLHTMTGVGYYLAPAP"
     gene            17009..18316
                     /locus_tag="EES43_RS00955"
                     /old_locus_tag="EES43_00980"
     CDS             17009..18316
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="EES43_RS00955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00980"
                     /product="ATP-binding protein"
                     /protein_id="WP_124266862.1"
                     /transl_table=11
                     /translation="MSGAARRRATIRTRLTLTYAGLFAGAGAAMIGLLYVFMKYVPVYG
                     ETLEGPGTKNGEPVLRPSFSGAMEPESLTLRPDCSAPPESGGFLDAAEGVLRRLTSSGD
                     TATAAMCTSPTGSVTSFEVSTKEDFLHALLMFSAVALLVLLVIAVILGWFVAGRMLSPL
                     QRITTTARGIAGSTLHERIALDGPKDEIRELADTFDAMLERLDGAFQAQRRFAANASHE
                     LRTPLAGMRTVLQVALAAPQAYRLEDLGPKLLALNRRSTEITEALLTLARAEHGAVAQE
                     DVELDAVARDVCAQAVAQAERAEVSLTVSGRAGRLRGDPVLLRQLVVNLVDNGIRHNRP
                     GGTVAVRVAGREGGGALLVVRNSGRRLSRTDVERALEPFHRLDTRQADRPDRPAGHGLG
                     LAIVASIVRAHGGTLRAEPPADGGLEIEVALPGVVA"
     gene            complement(18416..18916)
                     /locus_tag="EES43_RS00960"
                     /old_locus_tag="EES43_00985"
     CDS             complement(18416..18916)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="EES43_RS00960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00985"
                     /product="hypothetical protein"
                     /protein_id="WP_124266863.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPAGSPARETEEGQVPFEVAQLLLALENDEPVEIVSSEDL
                     PVMQGDNLLIVRRIKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     misc_feature    18919..18929
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            complement(19017..20183)
                     /locus_tag="EES43_RS00965"
                     /old_locus_tag="EES43_00990"
     CDS             complement(19017..20183)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="EES43_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00990"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_124266864.1"
                     /transl_table=11
                     /translation="MPKEPVAVVGIGQTKHVAARHDVSIAGLVREAAARALEDAGLTWS
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAAGLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPGTVGS
                     LVAYKDRRNALKNPYAHIHDTGITLEQVQSSPMLWDPIRYSETCPSSDGACAMVLTGRE
                     GAARSPHPPAWVHGGAMRSEPTLFAGKDFVSPRAGRDCAADVYRQAGITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFAAEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGEHQVDGAARALGHAYGGGAQFFSMWLVGSEPPPG"
     gene            complement(20176..21228)
                     /locus_tag="EES43_RS00970"
                     /old_locus_tag="EES43_00995"
     CDS             complement(20176..21228)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550730.1"
                     /locus_tag="EES43_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_00995"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_124266865.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQTAHRRRTDELSEVDLLMPVLHQVLDATGLKANEI
                     GFTCSGSADYLAGRPFSFTMALDGVGAHPPISESHVEMDGAWALYEAWVKIQTGEADTA
                     LVYAYGKSSPGELRDVLTRQLDPYYLAPLWPDSVALAALQTQALIDAGVTDEPALARVA
                     ARNRAAATTNPHAQLAGDVPAGDYVVHPLRTGDCPPIGDGAAAVVLAAGDTARALCRRP
                     AWIRGIDHRIEAHGPGVRDLTDSPSARLAAQHAGAFERPVDTAELHAPFTSQEVVLRRS
                     LSLGEETRVNPSGGALAANPVMAAGLIRLGEAAAGIHRGESDRALAHATSGPCLQQNLV
                     AVLEGESAHA"
     gene            complement(21229..22176)
                     /locus_tag="EES43_RS00975"
                     /old_locus_tag="EES43_01000"
     CDS             complement(21229..22176)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="EES43_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EES43_01000"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_124266866.1"
                     /transl_table=11
                     /translation="MSDVLSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTDDGRI
                     LVPPVEYDPVTAREIRDLVEVAPAGTVTTWAWNPAPRRGQPLDTPFAWVLVRPDGADTA
                     LLHALDAPGPEAVHTGMRVRIRWAARRTGAITDIACFEPDDGEASTAHPLPHSGEFADP
                     VTGIVTPARLDYVHTTGRAQSAYLKALEGHRTVGERCPACRKVYVPPRGACPTCGVATD
                     EQVEVGPRGTVTTFCIVNIKAKNLDIEVPYVYAHIALDGADLALHGRIAGIPYDQVRMG
                     LRVEPVWTEEARHPDHYRPTGEPDADYDTYKELV"
ORIGIN
        1 ttgggatagg cgggggtgag catcatcgcg tacgcggaga accgcatccg gtagcgcagg
       61 gtggccgccg tcgcctcgaa caggggccgc ggcatccggc ccagggccag cgtgatcagc
      121 caccacacga aggcgaggac ccaccacccg tacagcgcca ggctctgcac gaccgccgcc
      181 gggatcatca ggaagacgcg gaacaggacg gcgagccggt tgagcgcggt ggcccgcgtc
      241 tcggcctgga ccgggaagtc gggcgacggg gtgagcgcga agggcgggta gcggtcgatc
      301 agcagcatct cgctcgcgga cacgcgcatg tcgtagccga ggaacccggt gaggaaccgg
      361 aagacaaaac cgggcagccg gcccagcacc agcgcggcga accagccgac gacgacggtg
      421 accagcgccg cgatgtgcag gaagaagagc acgacgaact gcgggatcag caggagcagc
      481 cgtaccagga ccgtcagccg tcgttgacgg tccggctcga cgatgtccag aaccggtctg
      541 aactcgtccg cgtccctctc ctcgcggccc gggctccact ggccttcggc catgtcgcac
      601 ctcctcggca gggtccgtgc ggcgtccgcg cgcaggacgt cccctcacgc tgcggccggg
      661 ccgccgcccc cgcaaacggc cgcggcccga acgggtgccc aggagttcgg gtcacccgtt
      721 cgggccgcgg agccggcgcg aggcgtcagc cccgggggcg tcctcagcac tgctgaggcg
      781 tccttcagcg cctgcggaag cggtcgagca cggtgtgtgc gcggccgggg gcgggcccgg
      841 tactcgttcc ggccgcctgc ttcccggtga gtgtcttcgc tccgttcccg cgcgccggtt
      901 ccggcttcgt ttccggcttc gtttccggct tcggttcggc ctccggcgcg gccgtgggca
      961 cgggctccgg ccgcggcgcg tcggcgtaca cgtagtagcg gtggctgatc cggcggccca
     1021 gcagcaggta gccgaggagc gcgcccgacg tgttgaggat gacgtcgtcc acgtcgaagg
     1081 cgcgccccac gaccagggcg ccctggatca gctcgacgac gatcatgacg accgccgtca
     1141 gcagcgtcag acggatcatc cgcaggcgcc gcgacacgat gaagggcagc aggagcccga
     1201 acgggacacc gagcaggagg ttgccgcccg cctgcttgca cgcggcgagg aaggtgtagt
     1261 cctcggcgta ctcgcgcagc gaacggccgg gttgcaggtt cgatgtcacg aggtcctcgg
     1321 aggccggtga cggcgtgagc gtcaccctgg ccagaaagac ggagaacgcc accagtccca
     1381 gcagcaccac cgtcagcacc gcgacgcgca tcagcagccg cgcccatgtt ccctgtccct
     1441 ggcgggagtc agcctctgca gtcatggcgg tcgaatgccc ccgacggacc ggaacacacc
     1501 cgtgcgggac gcccggcggg aatacgtccg gccttccgcc gccgcctgcg acgatgggcg
     1561 catgaacgca cgtgagaaga aggaccggct ggccgaggcg gagcggctgc gcaccggagg
     1621 gcggcccgag gaggcgcgcg agcggctgct ggcgctgacc acccggttcc ccgacgacgc
     1681 cgaagtcgcg taccggaccg catgcgtcca tgacgtcctg ggcctggaga cggaggccgt
     1741 gccgtactac gaacgcagcc tggcgggcgc cggtctcggc gcggaggacc ggcgcggcgc
     1801 actgctcggc ctgggcagta cgtaccgggt gctggggcgt tacgggcagt cggtggagac
     1861 gctgcgccgc ggggtggagg agtttccgga cgacggcgct ctgcggacgt tcctgtcgat
     1921 ggcactgttc aacatcggtg agcacgacga gtccatgcgg ctgctgctgg agctggtggc
     1981 ggcgaccagc gacgacgagc atgtgcggcg gtaccggcag gcgatcgccc actacgcgaa
     2041 ggatctgcgc gccaccgcct gacggcgggg cgcggcgcgc cgtgcggccg gtcgcgcgca
     2101 cgtacggggc ggcccgcgcc gacaatgcac ccgtgcactc cccctccgcg ccctcctccc
     2161 ccaccggtcc ctcctcgccc gctccccggg accacggtgt ccggcggcgc ggtgagtggg
     2221 ggccgctgtt gttgtcggcg gcctcgggcg cggcggacgc gttcgtcttc ctgtgcgtgg
     2281 gtgaggtctt cgcgggggtg atgaccggga atctggtgct gctcggcgcc tcggcagccg
     2341 gcgcgggtga gaacggggtg gcgctgaagg tggtggccgc gctgggagcg tacgccgccg
     2401 gggtcgccgc aggcgcggtg ctggccgggc ggctgggcct gcggctccgg gtgctgctgc
     2461 gcgtcgagac cgtcctgctc ggcgcggcgg cggtcctgtg gggactggac ctggtcccgt
     2521 cgtacggcga ccggatcggg ctgctcgctc tggtgtcggt ggcgatgggg gtgcaggccc
     2581 gtatcggggg aacgccgacg aactacttca ccggcacgct gacctcgctc gcccggcggg
     2641 tggccgagcg ggagctgcgg gccggggacg ggtggctgac gggccggctg gtcgcggtgg
     2701 tcgccggggc gctgctggcc gggctgacgc agcggtggtg gagtccgggc gccgcggtgg
     2761 gtccggtggt cctggcggcg tgcgcgctgg ctctcgaaga ggcgggccgc cgtcggccgc
     2821 ggcgggacac ggggaagccc cggccggatc gggggaatcc agccggggcg gctcaagggt
     2881 ggccgtgaag ggcggtcgcc tcctggcgaa gggctccatg gggcttcagc cgaacgatct
     2941 tccccatggg cgagaggtga ggcccgggga cactgttccc ttcacgtcca cgtatagatg
     3001 aacgataaac cactggtcgg tgttcccggc gacggcgggc cgccgatgtg atccacggca
     3061 cggaatcccg ccctcccctt ccggtggacc cactcggcgt ccgccccgac ctccggtcag
     3121 ctctccggcg tcccaccgtc gccgtagcgg cggcggaact tctcgacgcg tccggccgtg
     3181 tcgagcacct ggcgaccacc cgtgtaaaac ggatggctcg cggacgaggt ctccacgtcg
     3241 atgacggggt aggtgttgcc gtcctcccac gtcacccgct cgccggaatc agcggtcgaa
     3301 cgggtcagga aggacgtgcc cgcgacccgg tcacggaaga cgacgggacg cgattcgggg
     3361 tggatacggg gcttcatgga tgcgttcctt cctcatcgcc gtgcggcggt ggcgttcgcg
     3421 ggcgccgggc agagcggccc ggtcggccat ctcgcggaaa cggctcgttc agcgggtctc
     3481 gcggaacagc acgtgctgtc cggcggcgga gtcgaacttg cgcagctcca gccggtcggg
     3541 ggtgttgcgg cggttcttgc gggtcacata gctccggccc gttccggcgg tcgaccggag
     3601 ggtcacgatc ggcctgagtt cactgcgtgc catgggcgcc tcccgttgtt ccggggtccc
     3661 ggccccttaa caggaacggg attcgttttc gttctggtcg gataacacgg tcggccccgt
     3721 cggcattccc ggcccggacg ccccggcagg acgcccgacc acgaccgctc gcccgaggga
     3781 gcgggacact tcggcgagcg cgctccggcc gtccacccca agcccatcct tcgaaaacgc
     3841 tcacgacccc ggacacacct tccgcctccg tcgcccgcag ggccgaaccg ggacatcccg
     3901 gccggagcac cgcagcccgt cagggccttc actgttcgga cactccgtca atctccttca
     3961 cccgcaagcc tgttcgggat atcacctcac catcgagccc atggcatatg ccagaagcaa
     4021 caacgtatcg agtgtcgcca aatcccttac gggctccgcg aggctgtgcg aaagtcggaa
     4081 gcggcccacc cccctcagaa ccggccgagc cgcgcctgta tcggagtacg agatgccgtc
     4141 ccatctgttc gcggaccgcc ccgcaccaca gcaacccgcg cacgatgccg tcgacgcctt
     4201 gatccaccga gcgcaccgac tgcgcgggga cgtggacgcc gtgcggcggg acgccgtcac
     4261 cgacgaggag aacgcccagc tgcgctggca gcgcgccctg tgcgagctcg ccgtccacca
     4321 cctggacaac ctcggcgcgc atctgagcca gctcagggcg ggcctgccgg agcagcggtc
     4381 cacgggcacc gcccccgacc gccggcgggc tgccgctccc ctcgatgcct cgccgccgag
     4441 ccgggtgggc agcgccgagt ggaacctcct caccgacgag gtcagctggt cgaaggagct
     4501 ctacgagatc ctcggccggc cccgcgaatc ggagccgctg tcactggacg agatgccctc
     4561 cgtcctgctg cccgaggacc agccgctgct cacctccatg gtcacggggt gcctcgtgga
     4621 cggccggccg atggacgggg agttccggat cgtgcggccc gaccgccggc tgcgcaccgt
     4681 gcacatgacg ggcgagccgg ttctcgacgc ccacggccgc accgcctcca tgtgggcggt
     4741 cctgcgggac gtcagcgagc tgcgccgcgg tgaggaggcc gtgagccgga gccaggactc
     4801 ggtgcgccac gaggagcaca tcgagcgcac cgagcaccgg atggccgtgg aactccagga
     4861 ggccgtcctg ccgccgtggc gcggttcgct gcgcctgccg cgccagggcc ccggcgcgct
     4921 ggacatcgcc gcccactacc tcccctcccg gtccagcggt ctgatcggcg gcgactggta
     4981 cgacgcgatg gaactgccgg acggccgcac gctgctgagc gtcggcgacc tggccggcca
     5041 cggcatcccc gccacctccg ccatggccat gctgctcggc gccctgcgcg gcatggcggt
     5101 cgccgggatc gagccgggcg cactgatggg ccacctcaac caactgctcg aatcgtcgat
     5161 ccagccggcg ctgggcagcg ccctgtgctg ccgcttcgat ccggccaccg gcatcctctc
     5221 gtggtcgcag gccgggcatc ccgcaccact gctcttccgc gacggaacgg gtcggctcct
     5281 tcccccgccg gacggggtgc tgctcggcgc cgcctccgag gtcgccttcg agcaggacga
     5341 ggtacgcctg ctccccggtg acgtactggt gctccacacc gacggcctga cgcggcgcag
     5401 cgaccggggc gcgggtccgg aggccctgct ggggctggct ccccgcttcg cccgtgcccg
     5461 tacggcacag gagtgcgtcc ggtccgtcgt cgaggagttc ggcgggtcgg agcgcctgga
     5521 cgacgcgtgc gtgctggtcg cccggttcgg cgggtgagcc ggttcggggc atgcggaagc
     5581 gcctgcgcac aggagggttc gccgcccgcc gcacggacgg cgtcacgaca cggcgcgggc
     5641 tgcacccgct gcgaggcctc gacgcggggt gcgcgcgagc ccggatcggg ggccggttca
     5701 ggtccgctgg tccgggacct tcttcgcggc cggccgttgc ggcagcgatc gttcgatctc
     5761 ctcgcgcaga tcctggatgc cggggttgcc cgagaaccgg ccggtgaggc ggtacatctc
     5821 gcgcagccgg tcccaggtgc ggtgcgagga ggtctccccc atcgacacca gcgccaggcg
     5881 ggcgtagcgg tcggcctgtt cgggatcgtc ggcgatgaag caggccgagg cgagcgagat
     5941 gtagtcgaag atcttcgacc gctgccggcc gttgacccgc agctccagcg cctccttggc
     6001 gtggcgctgg gcgatgaccg cggcgctgga gtcgtgctcg gccagggtgc ggaaggccag
     6061 tgcctgcatc ccgcgcaggt cggcctcgtc gaacatctgc atccagctcg gcgacggccc
     6121 gtcgccgcgg tccgacacga acagctcctc ggcctcgccg agcgtgcgcc gcatcgcctg
     6181 gccgtggccc atggccgcct gcgcccatgc ctcgatggtg tgcagcatcg cctgcgtccg
     6241 gggcaggttc tcctcgcccg agccggacct ggcgagcttc atcaggtcca gcgcgtcgtc
     6301 gggccgtccc aggtgcacca tctggcgtgc cgcgcgggag agcgcctcgc ccgcgcgcgg
     6361 tcggtcgccg ccctcgcggg ccgcgtgggc ggcgatcacg aagtacttct gggcggtggg
     6421 ttcgaggccg acgtcgtgcg acatccagcc cgcgaggacg gcgaggttgg cggccacgcc
     6481 ccacagacgg cgctggaggt ggtcggggtg gtggtaggcg agcatgccgc ccacctcgtt
     6541 gagctggccc acgaccgcct tgcgctggag ccctccgccg cgtgaggcgt cccaggcgcg
     6601 gaacacctcg accgagtgct ccagggcctc gatctcctcg gagccgaccg gtgcggcctc
     6661 gtaccggtcg tagccggcgg gatcggcgtt catggagtcg ttggcgcgtg gtgcgccggc
     6721 cgtcgcagcg gggtcgctgt gcagccaatc gtacatgggt ccggtgatgg cggagccggc
     6781 ggcgagcgcg gcgcccgcct ccaccaagcc gcgtcggttg agcatgaggt ccattcccgt
     6841 gaattcggtg aggaccgctg ccgtccgctt gggcgcccac ggcagttgat cggggtggtg
     6901 ttccgtccct gagtcacgcc gcttacccac acgcccgcgt cggccgaacc cgaggtcctc
     6961 gatggtcacg acacggccga gccgctcggt gaacagggca gccagcactc cgggcacggg
     7021 atcgcgcggg gactccccca tgtcgatcca gcgcctgacc cgcgaggtgt cggtggccag
     7081 ctgcggatgg cccatggccg ccgcctgccg gttcaccatt ctcgcgagtt cgcccttgga
     7141 ccagccggcc aggccgaaca ggtcagaaag gcgggtgttg ggttctccgg tcacgtcaag
     7201 cccccaggtt ctcggctgac ttgacactaa ccccctgtca gatgcggagt gactattcgc
     7261 cagggttcgc cagggtgcgc cagatggtct gccacccgcg gtccggtgtc aggtaggaaa
     7321 gcgccacccc gcccggcagc cctcggtact ccccagggtg ccgaacggcc gtcggtcggg
     7381 ttggcgcacg caacctgtcg gcgcgcgaag ggatctgtct cgcccatgta cacagcatcg
     7441 tcctccgtgt ccgccccgcc ccggccgctc cgtcctctgg ggacgggcgg cggaccgtat
     7501 ctcgcccccc acgccggcgc accggcgcag gctctgggcc ggacccggcg ggcggcggga
     7561 ccgggcgcgg gaccgctcag cggacgcatc gacctgtccg ggccccaggg ggcgcaggtg
     7621 cggatggcca tcgcctccgt gcagcgcatc tgccccgagt tcaaccccgt ccaggtgctg
     7681 cggcgcagcg gccggtcggt gttgatcgtc ggcgcggccg gccgggcaac ggccgtggcg
     7741 aagtgcttac tggaccactc gcccgcctgg acggaacggt tccggcacga aatagcggcg
     7801 taccgcgcgt tcgtccggca ccgccccccg gttcgggtgc cccggctgat cgcggcggat
     7861 ccggagaact gcaccctggt gatcgagcgg atgcccggcc gggtggccgc tctgacccgg
     7921 catccggccg aggctccgcc gcgggccgac ctgcgggcgg cgctgagcgc gatcagccgg
     7981 gtgaacgcct ggcgtccgcc gcccggcctg ttcgaggcgc cgctggacta cgcctcgcgc
     8041 atctcgcgct atcacgagct cgggctgttc accgaccgcg acctcggcga tctccagaag
     8101 ctgctgcacg ggctggcgca cgcgggcggg cggggaggca tggggcagtt ctgccacggt
     8161 gacgcgctgc tctccaacat cctgctctcg cccaccggac cggtgctggt cgactgggag
     8221 cacgcgggct ggtacctgcc gggttacgac ctcgcgacgc tgtgggcggt gctcggcgac
     8281 gccccggtgg cgcggcgcca gatcagccag ctggcacagg cgcggggacc ggccgcacgg
     8341 gacgcgttcc tggtgaacct gatgctggtt ctgacgcgcg agatccgcaa ctacgagacg
     8401 gcggtgcagc gcagcatgcg tgaggcgtcc tcgccgggcg cgggtcagga gcggccgggc
     8461 gcgctctcct ccggcgagga gcagcggctg ctgctgcgcc ggctgcacga cgactgcgcg
     8521 atggcgcgcc gggccgtacg ggctgcggtc ggcacgcgct gagcgggctg acgccgggga
     8581 acggggccgc gcccggaggg tgacgaggag cggcccggga tcgatcgtcc cccggcggat
     8641 cgaccatggt gagggggaag cgcgctgcgg gaccggtgcc gacacaccgg gcccgcggcg
     8701 cgctgttgtg ctgagggagg tcgggaaggg agttcagggg cgtggcaggg ccggtgctcc
     8761 cggtccgccg cgccccttcg cgcgtcctcc gccgggggcc ggagcgtgtc cgtgcggtga
     8821 ctgtgcgccg cgtcgggggc cgccgcgggt gaggcatgcc acgagaccca cgtcacctac
     8881 gacctccgat cgttgacgcc gtccctccgc gaggccgcaa cggtcgccct aaagcggtca
     8941 tagagcccta tctcacgatg gcgggtagta aacggggtca ttgcgtcggt tctcgggccc
     9001 cgctaaccat ggatcccggc aagcaccgag tacgagccag cgacgagcgc cgaccggcgg
     9061 tccgcggccg attcccttcg gtacctgctc acgcggcgtg caggccgcgc agcccgtccc
     9121 ccatcaggaa gagctcacgc atgccccgcc tcaccaccat ccgcatcacc cgctcccaca
     9181 agctcgccgc cgccgtgctc gtcgcggccg gttccgtcac cgccgtcgcc gccaccggtg
     9241 gccagagcga cgcccgcccc gtggaggccc gctcctccgt cgcggtccag cccgtcgccg
     9301 ccgccggcgt ccccaccgcg aaggacgcgg cgaagaaggc ggccgaggag accgcggcga
     9361 agaaggccgc agccacccgc gaggcgaccg ccgagaagga cgcggcggag aaggaccgca
     9421 cggagaagca ggccgccaac cggtccaccg agcgcaaggc cgctccgaag cagtacaaga
     9481 acaacctcga cggctggata cgcgagtcgc tcgacatcat ggagaagaag aacatccccg
     9541 gctcgtacga gggcctgcac cgcaacatca tgcgcgagtc cagcggcgac ccgaacgccg
     9601 tgaacgactg ggacatcaac gcccgcaacg gcgtgccctc caagggcctc ctccaggtga
     9661 tccagcccac cttcgacgcc taccacgtca gcggtacgcc gaagaagctc accgacccgg
     9721 tcgccaacat caccgccgcc gccaactacg cggcggaccg ctacggctcg atcgacaacg
     9781 tcgactccgc ctactgagcc gcccggcgcg ccgacggcgg cgcgcactcc gagccgaggt
     9841 gatggtgcgt catatgcgtt acgggtaggc cacaccacga gtgtgcttat gtgactaatc
     9901 aacatcatgc gtgccccgga tggccgaagg gtagtgctcg cgcggacacc acctgtccgc
     9961 gcggacaccg cgcggaggct tctggaaagg catgacgcac atggcacagc ccttctcact
    10021 gccggacttc tacgttccgt atccggcgcg gctcaaccct catgtggagg cggcacgcac
    10081 gcacacccgg caatgggcgc gaggcatggg gatgctggag ggctccggga tctgggaggc
    10141 ggcggacctg gaggcgcacg actacgcgct gctgtgcgcc tacacgcatc ccgactgctc
    10201 ggccgaggcg ctgtcgctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggag ctgttcaagc gcacgcacga ccgcgagggc ggcaagcggt atctggaccg
    10321 gctgccggcg ttcatgccga tggagcgggg cgcaccgact ccgaagccgc ggaaccccgt
    10381 cgaggcgggc ctcgccgacc tgtgggcgcg gaccgtcccg gcgatgtcgg acgcctggcg
    10441 ggcgcggttc gccgaggcga cggagaacct gctcaacgag tcgctgtggg agctctccaa
    10501 catcaacgag gggcggatcg ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgcgccc tggtcggcgg ggctggtgga gtacgcggcc ggcgccgagg tgcccgcctc
    10621 cgtggccgac gcgcgcccgc tgcgggtcct gcgcgacgcg ttctcggacg gggtgcacct
    10681 gcgcaacgac ctcttctcgt accagcgcga ggtggaggac gagggcgaga acagcaacgg
    10741 ggtactggtc ctggagcggt tcctcggctg caccacgcag gaggccgccg aggccgtcaa
    10801 cgacctgctc acctcgcggc tccagcagtt cgagaacacc gcgctgaccg agctgggacc
    10861 gctctgcgcg gagaagggcc tcggaccggc ggagagcacg gcggtcctcg cctacgtcaa
    10921 ggggctccag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccggtacat
    10981 gaacgggggc ggcgcgggtg aggcggtggc cggcttcggc atgtccgccg cgtcgatcag
    11041 gttcaccacg cgtgcggagt cggcgcgggc gcgcagccac acccatgtgc cctaccagca
    11101 cgtgggcccc tcgctcctgc ccgacttcga gctgccgttc ggcacgacgc tgagtccgca
    11161 tctggagggg gcgcggtcgc ggctcgtgga ctggtctcgg cggatgggca tcctggaggc
    11221 gcagccgggc gtgccggggt cgcacatctg ggacgaggag cggctgatcg cgatcgacct
    11281 gccgctgtgc gcggcggggc tgcatccgga cgcgacgccg gacgaactgg acctctcctc
    11341 gggttggctg gcctggggaa cgtacgggga cgactggttc ccggtggtgc acgggcggac
    11401 cagggacctg gcgggggcgc ggctggccaa cgagcggctg tcgctgttca tgccgctgga
    11461 cggcgggggc gcgccggagc cggtcaacgc gctggagcgg ggactgggcg atctgtggcg
    11521 ccggacggcc gcgccgatgg acctgagcgg gcggcgcacg ttccgggagg cggtcgagtc
    11581 gatgaccgcg agctggctgt gggagctggc gaaccaggcg cagaatcgta ttcccgaccc
    11641 ggtggactac gtggagatgc ggcgggccac gttcggttcg gacctgacga tgagcctgtg
    11701 ccggctcggg cacggacgga aggtcccgga cgccgtctac cgcagcggcc cgatgaggtc
    11761 gctggagaac gccgcggcgg actacgcctg cctgctgaac gacctgttct cgtaccagaa
    11821 ggagatcgag tacgagggcg aggtgcacaa cggcgtcctg gtcgtgcaga acttcttcgc
    11881 ggtcgactac ccgacgggcg tggcgatcgt gcacgacctg atgaagtcgc ggctgcggca
    11941 gttcctgcac gtggccgagg tcgaactgcc cgtcctgtac gacgacttcg atctggacgc
    12001 cgaggcgcgg gaggtgctgg cgggctatgt gctggagctc aagcactggc tcgcgggcat
    12061 cctgatctgg caccggggct gccggcggta ccgcgaggag gacctgcggc gcgggcacgg
    12121 cacaccgtgg cacatcagcg ggcccacggg actgggcacg tccgcggccc aggtgacacg
    12181 gctgatggcc cagttggcgg gcagcggggt gtagccgggc cggcgcggag ccggtgaagc
    12241 ggggccgggg cccgtcgtgc ggacagcgcg gcgggcccgt gccgtgcggc ggcggtgcgc
    12301 cgggtcccgc tcaccggagg tcccgggtcg cgcagaccgg atgtttcgtg aacgtaagga
    12361 aatgcgcaga cggtggcgat aagccgggtg cgatgtgctc ggtaccaggc gtcgccaccg
    12421 aggtcctcct cgtcttcccg gcggcgtcct cgttccctgt ccggcccctg agccgcagca
    12481 gcaccggagg tccccatgcg tgtgtccgcc cgtacttcgc gacaacgtct cgccacgagc
    12541 gtgctggcgg tgctgctcgc cgtcggaacg gcggcgtgct cgggggaggc ccccgacaag
    12601 ccagccgcgg acgcgcccgc ggcaggcgac acggcgggcg gcacgggcgg cggggattcc
    12661 acgccggact ccggacagga ccccggtgtc gtctacgcgg cgtgcatgcg ggacaacggc
    12721 gtcgaggtcg acgacccgaa gccgggcgag cggccgcaga ttcccgaggg cactccgccc
    12781 cgggtgctgg acaagctgga gaaggtctgc ggcgagcttc ccggcagcgg cgcgatgacg
    12841 ggcgggttga gttccgacgt tctcaagtcg cccgaggtcg aggcgctgcg gctgacgtat
    12901 ctgacgtgta tgcgcaagaa cggctacgag cagccggagc cggacgcgaa cggcaacgtg
    12961 agcatgcaga tcacgcccga gtacacggcg gcccagaagg cgtgcacgtc cgagaacgac
    13021 gcgctcagca agaagatcaa ggagctcgcg aagcagggcg gcgcccagtg agagaggtcg
    13081 tcgaaccggt cgagggcgcc gaggagcacg gggcgggcga cgatcccgcc gtcaccgtcg
    13141 gccggacgcc cggggccgac ggttcgggcg ggcgcggacg cgggcggcgc ggtggtggcg
    13201 gcaggggccg tcgtgggctg ttggtggccg tcgccgtggc cgtggtggcc gccgccgtcg
    13261 gcgcgggcct gctgtacggg cggacgggga cggaacggga gcccgcctcg ggcgagccgt
    13321 tgccgcccgc cacggagaag gccgtgcgcg gggacctggt ctccgaggtg cggtccttcg
    13381 gcaccctgca gttctccggc gaccgtcgtg tcaccaaccg gatcgcgggg accttcacct
    13441 ggctgcccgc ggcgagcagc gtcgtcgaac gcggcgagcg gctgtacgcg gtcgacgacc
    13501 ggccggtggt cctcatgcgc ggcgacctgc ccgcctggcg ggagttcagg gccaggatga
    13561 aggacggcaa ggacgtccgc atgctggagg agaacctggc ggccctcggc tacaccgact
    13621 tcaccgtcga cgaggagttc tcccggaaga cggaggcggc gctgaagcgc tggcagaaga
    13681 acaacggtct gccgcagagc ggaaagctcg aactgggccg ggtcgtcttc gcccccggcg
    13741 acctgcggat caagaagtcc gcggtgcgcg cgggcgacgc ggccgtgccc ggcggcgagg
    13801 tgctgcgggc cggcggctcc cggcagcggg tcagcaccca ggtgcccctg gaggcgcagg
    13861 aactcgccct cgaaggcgcg tcggtggaga tcgagctgcc ggacggcgac cggaccgacg
    13921 ggaccgtggc ctcggtcggt cagcagcggc tgaacgaaca gggcaagaag gtcgtgcccg
    13981 tcaccgtgcg tctcgactcc cccggggacg tcgggaagct cccgagcgcc gacgtcaccg
    14041 tggtgctgcg caaggtggag gccaagaacg tgtactcggt gccggtcacc gcccttctgc
    14101 cgctgcccga cggcggattc gcggtgcaga tcgtcgaggg cggccaggtc cgccgggtga
    14161 aggtgaggac cggcgcgttc gccgacggca gggccgaggt gagcggtccg ggcatcaccg
    14221 agggcgtacg ggtgggggtg ccgcgcctgt gaccgccacc gctcccggcc ccgcggctct
    14281 gccccgcggc ctcgccggca cggccgagcc ggtggtccgg ctgaccggcg tgggccgctc
    14341 ctacggcgac ggggagcacc gggtccacgc gctgcgggac gtgaccgtcg acatcgggcc
    14401 gggggaactc ctcgccgtcg tcggcccctc cggatccggc aaatcgacgc tcctgcatct
    14461 cgtcggcacc ctggaccgcc ccagtcacgg acaggtcctc gtcgacgggc acgacgtggc
    14521 ccgcctcgac gaccgcggcc tctccgccct gcgcgcccac cggatcggct tcgtcttcca
    14581 gcacttccac ctcgccgagg gcacacgtgc gctcgacaac gtcgcggacg ggctgctgta
    14641 caccgggatg ccccgcaggc ggcggcggga gcgcgccgag gcggcgctgc ggcgggtggg
    14701 cctcggccac cgtctggggc accgctcgca ccagatgtcc ggcggcgagc ggcagcgcgt
    14761 cgccatcgcc cgcgccgtgg tgggagagcc ggctctgctg ctggccgacg agccgaccgg
    14821 ggcgctggac acccacgcgg gcgggctcgt cgtggagttg ctgcgcgagc tgcaccgcga
    14881 cggcaccacc gtcgtgatca tcacgcatga caacgagctg gccgccggcc tgccgcgccg
    14941 gctgctcatg cgggacggcc ggctcgtcga cgacatcgcc gccggaccgg ccgtgcggct
    15001 caggaacggg gacgccacgt gaaccgcacc catccgctcg cctcgcggct gcggtccggc
    15061 gatctgctgc ggctgggcgc gaccgggctg cgtacgcgtc cgctgcgcgc ggtgctctcc
    15121 gccgcgggca tcgccatcgg gatcgccgcg atgatcgccg tgctcggcat ctccgcgtcc
    15181 agccaggcgc atctcgacgc cgaactggag aggctcggca ccaacctgct gaccgtcgcc
    15241 ccgggcgagg atcccgatac cggtgctccc gtcccgctgc cgacgaccac cgtgcggacg
    15301 gtcgcccgcg ccgacggcgt cgactccgtc agcgcgacgg gcgagatcac gggcgtcggg
    15361 gcctaccgca acgcccgggt gcaccgggcc gagtcgaacg ccctgtccgt cctcgccgtc
    15421 gaggggaacc tgctggccac cctgcgcggc accctggccg cgggcggctg gctggaccgg
    15481 gcgccggccg gctacccgac gaccgtgctc ggccaccggg ccgcccagcg gctcggtgtg
    15541 acgggcgcgg gcgagcaggt gtggctcggc gaccgctact tcaccgtgct gggcgtcgtc
    15601 gcgccggtgc cgctcgcgcc ggagctggac accgcggtgc tggtcaaccg ggcggcggcc
    15661 gagacgtacc tgggcttcga cgggcggccc accctggtgt acgagcggtc cgccgaccac
    15721 ctggtggaga gcgtacgggt gctgctgccc cgggccgtcg acgccgagaa tccgcagaac
    15781 gtcgtcgtca gccgtccgtc ggacgcgctg aaggcacggc aggcggccga ggagtccttc
    15841 accggcctgc tcgtggggct cggcggggtg gcgctgttcg tcggcggtat cggggtggcc
    15901 aacaccatgg tcatcaccgt catcgaacgc cgccgggaga tcggcctgcg gcgcgcgctg
    15961 ggtgcggccc gccgccacat cacccgccag ttcctggtgg aggccctgct gctgtccacg
    16021 ctgggcgggc tggccggagc cgcgctcggg gccggtgtca ccgccggata cgctctcagc
    16081 cggggatggc cgaccgcgat tcccctggtg gccccggtcg gcggcgtcgc cgcgacgatg
    16141 gtcatcggcg ctctcgccgg gctgtacccc gctctgcggg ccgcccgcac accgccgacc
    16201 gtggcgctgg ccgcggcgtg aacgcggagc cggccgctcc ccgccgtccg cgcggcggga
    16261 agcggccggc gtccggcctg cgtccggcct gcggacggtg cgggcccgat cggcggcgct
    16321 acgagtcgga gcgaggagag gaacacatgc gggtgctgat cgtggaggac gagccgtaca
    16381 tggcggaggc cctggtggcg ggtctgcgcc gagaggccat ggcggtcgac ctggcgaccg
    16441 acggggcgtc cgcgctcgac cggctgagct gccacgacta cgacgtggtg gtcctggacc
    16501 gggatctgcc ggacgtgcac ggcgacgagg tgtgccgccg gctgacgtcg gcgcggagtc
    16561 cggtgcggat cctgatgctg acggccgccg cgtcgctgga cgaccgggtg ggcgggctcc
    16621 ggctcggcgc cgacgactac ctgcccaagc ccttcgagtt ccccgagctg gtggcccggc
    16681 tgcacgcgct gcaccgccgt gcgggcacac cgccgccgcc cgtgctggac tgcgccgacg
    16741 tgcgcctgga cccgttccgg cgcgaggcgt accgggacgg cagatacctg cggctgaccc
    16801 gcaaggagtt cgcggtgctg catctgctga tggcggcgca gggcggggtc gtcagcgcgg
    16861 agaccctgct ggagaagggc tgggacgaga acgcggaccc gttcaccaac gcggtgcgcg
    16921 tcaccgtctc caatctgcgc cgcaagctcg gatcgcctcc cctgctgcac accatgaccg
    16981 gcgtcggcta ctacctggcc ccggcaccgt gagcggcgcg gcccgccgcc gggccaccat
    17041 ccgcacccgg ctgaccctca cctacgccgg gctcttcgcg ggcgcgggag cggccatgat
    17101 cggcctcctg tacgtcttca tgaagtacgt cccggtctac ggcgagacgc tggaggggcc
    17161 ggggacgaag aacggcgagc cggtcctgcg cccctcgttc tccggcgcga tggagccgga
    17221 gagcctcacg ctacggcccg actgctccgc cccgccggag agcggcgggt tcctcgacgc
    17281 ggccgagggc gtcctccgcc ggctcacgtc gtccggggac accgccacgg ctgccatgtg
    17341 cacgtccccg acgggcagcg tgacgtcgtt cgaggtctcc accaaggagg acttcctcca
    17401 cgccctgctg atgttcagcg ccgtggcgct cctcgtgctg ctggtgatcg cggtgatcct
    17461 cggctggttc gtggcggggc ggatgctgtc cccgctccag cgcatcacca cgacggcccg
    17521 gggcatagcc gggtccaccc tccacgaacg catcgcgctg gacgggccga aggacgagat
    17581 cagggagctg gccgacacct tcgacgcgat gctggaacgc ctggacgggg cgttccaggc
    17641 gcagcggcgg ttcgcggcga acgcctcgca cgagctgcgt acgccgctgg cgggcatgcg
    17701 tacggtgctc caggtcgcgc tcgccgcccc gcaggcgtac cggctggagg atctggggcc
    17761 aaaactgctc gcgctgaacc ggcgctcgac cgagatcacc gaggctctgc tgacgctggc
    17821 gcgggcggag cacggcgcgg tggcgcagga ggacgtcgag ctggacgccg tggcgcggga
    17881 cgtgtgcgcc caagcggtgg cgcaggcgga gcgggcggag gtctcgctca cggtgtcggg
    17941 ccgggcgggc cggctgcggg gcgatccggt cctgctgcgg cagttggtcg tcaacctggt
    18001 cgacaacggg atccggcaca accgtccggg cggcacggtc gcggtgcggg tggccgggcg
    18061 cgagggcggc ggtgcgctgc tggtggtgcg caacagcggg cgcaggctga gccggacgga
    18121 cgtggagcgc gccctggagc cgttccaccg tctcgacacc cggcaggcgg accggccgga
    18181 ccgcccggcc gggcacggtc tcgggctggc gatcgtcgct tccatcgtgc gggcccacgg
    18241 cggcacgctg cgcgcggagc ctcccgccga cggcgggctg gagatcgagg tcgcgctgcc
    18301 cggcgtcgtc gcctgagggc cggggccggg acgggagagg gcgctggccg tcggccgcac
    18361 ggacggacgg cgtaaggccg tccggaacgc tccggacggc ctcagcaggg acgtttcacc
    18421 cctgctggaa cagttccgcg ggcagcggct tgaggagggt gtacaggtcg tcggtgatcg
    18481 gccggtccca gctggcgatg gtcacgagca caccgtcgct gcggtcgaac tggacgcagg
    18541 cgatccggct ctcggagagc ttgatccggc gcacgatcag caggttgtcc ccctgcatca
    18601 ccggaaggtc ctcggagctg acgatctcga ccggctcgtc gttctccagg gcgagcagca
    18661 gttgcgcgac ctcgaagggg acctggccct cctcggtctc ccgggcgggc gaaccggccg
    18721 ggaggttgcc gatgatcatg gccgggccgc gaccaccgta gaggtcgtag cggaggaaga
    18781 cgccctggca gctgccgtcg ggggcgggga gcagaccggc gccgaggttg ccgggccagt
    18841 cccccgggtc catggccagg acgtcgaagt ccgggcccgc gggtgttgcg gcgctacggc
    18901 ggcggaggaa ggacatgctg ccatgttacg tgtcccggct cacgtcgcgg agccgggccc
    18961 gggaggagcg gaggggccgc gggccgccgc ccggacggcc cgcggcgtgc tccgggtcag
    19021 cccggcggcg gctcggatcc gacgagccac atggagaaga actgcgcgcc gccgccgtag
    19081 gcgtggccga gcgctctcgc cgctccgtcg acctggtgct ccccggcccg gccccgcacc
    19141 tggagcgcgg cctcggcgaa gcggatcatg ccggacgcgc cgatggggtt ggtggacagc
    19201 acgcccccgg aggggttgac gggcaggtcg ccgtcgagtt cggtgacgcc cgcctcggtg
    19261 agcttccagc cctcgccctc ggcggcgaac ccgaggttct ccagccacat cggttcgtac
    19321 caggagaacg gcacgtacat ctcgacggcg tcgatctcgc ggcgcgggtc ggtgatcccg
    19381 gcctggcggt agacgtcggc ggcgcagtcg cggcccgcgc gcggggagac gaagtccttg
    19441 cccgcgaaga gcgtgggttc gctgcgcatg gctccgccgt gcacccaggc cggcgggtgg
    19501 ggcgagcggg ccgcgccctc gcgtccggtc aggaccatgg cgcaggcgcc gtcggaggac
    19561 gggcaggtct cggagtagcg gatcgggtcc cagagcatgg gcgaggactg gacctgctcc
    19621 agggtgatgc cggtgtcgtg gatgtgggcg taggggttct tgagggcgtt gcgccggtcc
    19681 ttgtaggcga cgagggagcc gaccgtgccg ggtgcgccgg tgcggcgcat gtaggcgcgc
    19741 acgtgcgggg cgaagaagcc gccggccccg gccagcagcg gctgctggaa gggcacgggc
    19801 agcgacaggc cccacatggc gttggactcg gactgctttt cgaaggcgag ggtcaggacg
    19861 gtgcggtgga cccgggcggc gaccaggccc gcggcgacga gtgccgtcga gccgccgacc
    19921 gatcccgcgg tgtggacgcg gagcatgggc ttgccgacgg cgccgagcgc gtcggcgagg
    19981 tacagctccg gcatcatgac gccctcgaag aagtcggggg ccttgccgat gacgacggcg
    20041 tcgatgtcgc tccaggtcag gccggcgtcc tccagggcgc gggcggcggc ctcgcggacc
    20101 agtccggcga tcgagacgtc gtgccgggcg gcgacgtgct tggtctggcc gatcccgacg
    20161 acggcgacgg gctccttagg catgagcgct ctccccttcc aggacggcga ccaggttctg
    20221 ttgcaggcag gggccggagg tggcgtgggc gagggcccgg tcggactcgc cgcggtggat
    20281 accggccgcg gcctcgccga ggcggatgag gcccgccgcc atcaccgggt tggcggcgag
    20341 cgcgcctccg gaggggttga cgcgggtctc ctcgccgagg ctcagggacc ggcgcagcac
    20401 gacctcctgg gaggtgaagg gcgcgtgcag ctcggcggtg tccacggggc gttcgaaggc
    20461 cccggcgtgc tgggcggcga gccgggcgga gggcgagtcg gtcaggtcgc ggacgccggg
    20521 gccgtgggcc tcgatgcggt ggtcgatgcc ccggatccag gcgggccgcc ggcacagcgc
    20581 ccgcgcggtg tcgcccgcgg ccaggacgac ggcggcggcc ccgtcgccga tgggcgggca
    20641 gtcgccggtg cgcagcgggt gcacgacgta gtcgcccgcg gggacgtctc cggcgagctg
    20701 ggcgtgcggg ttggtcgtgg cggcggcgcg gttgcgggcg gcgacccggg cgagggcggg
    20761 ctcgtcggtg acgcccgcgt cgatgagcgc ctgcgtctgg agggcggcga gggcgacgga
    20821 gtccggccag agcggggcca ggtagtacgg gtcgagctgg cgggtcagga cgtcgcggag
    20881 ctcgccgggc gaggacttgc cgtacgcgta gacgagcgcg gtgtccgcct cgccggtctg
    20941 gatcttcacc catgcctcgt acagcgccca ggcgccgtcc atctccacat gggactcgga
    21001 gatcggcggg tgcgcgccga cgccgtcgag cgccatggtg aaggagaagg gccgtccggc
    21061 gaggtagtcg gcggagccgg agcaggtgaa cccgatctcg ttcgccttca ggccggtggc
    21121 gtcgaggacc tggtgcagga cgggcatcag gaggtcgacc tcggagagtt cgtcggtgcg
    21181 ccgccggtgc gcggtctggg cgaaggcgac gatggccacg tctcgcatct acaccagctc
    21241 cttgtacgtg tcgtagtcgg cgtcgggctc tccggtgggg cggtagtggt cggggtggcg
    21301 ggcctcctcg gtccagacgg gctcgacgcg caggcccatg cggacctggt cgtaggggat
    21361 gccggcgatc cggccgtgca gggcgaggtc cgccccgtcg agcgcgatgt gggcgtagac
    21421 gtaggggact tcgatgtcga ggttcttcgc cttgatgttg acgatgcaga aggtggtgac
    21481 ggtcccgcgc gggccgacct ccacctgctc gtcggtggcg acgccgcagg tggggcaggc
    21541 gccgcgcggc gggacgtaga ccttgcggca ggcggggcag cgttcgccga cggtgcggtg
    21601 gccttcgagg gccttgaggt aggcgctctg cgcgcggccg gtggtgtgca cgtagtccag
    21661 gcgcgccggg gtgacgatgc cggtgacggg atcggcgaac tcgccgctgt gcgggagcgg
    21721 atgggccgtg gacgcctcgc cgtcgtcggg ttcgaagcag gcgatgtcgg tgatcgcgcc
    21781 ggtccgccgg gccgcccagc ggatccgtac ccgcattccg gtgtgcacgg cttcggggcc
    21841 gggggcgtcg agggcgtgca gcagggcggt gtcggcgccg tccggcctga cgagcaccca
    21901 ggcgaagggg gtgtccagcg gctggccgcg gcgcggggcc gggttccagg cccaggtggt
    21961 cacggtgccg gcgggggcca cctcgacgag gtcgcggatc tcgcgggcgg tgacggggtc
    22021 gtattcgacg ggcggcacca ggatccggcc gtcgtccgtg cggacgccga gcacggtgcg
    22081 ttcgcgcagt ccggtgagga aggcgctctg cacggggccg agggagcggg tgaaggggaa
    22141 ctcgaccacc agcggggcgc tgaggacgtc ggacatgggt gtctccttgg ctcaggcccg
    22201 gcggaagacg ggcg
//
