GCF_003726095.1 - 8 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP026031.1 (Niallia circulans)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	terpene-precursor,deazapurine	392,118	429,633
Region 2	cytokinin	1,115,782	1,152,408
Region 3	terpene-precursor	1,874,948	1,895,841
Region 4	arylpolyene	2,489,628	2,530,611
Region 5	lassopeptide	3,342,644	3,371,422	Low	paeninodin	ribosomal:unmodified
Region 6	terpene	4,235,044	4,256,939
Region 7	cyclic-lactone-autoinducer,lanthipeptide-class-iii	4,603,731	4,631,654
Region 8	triceptide	5,034,292	5,055,521

NZ_CP026031.1 - Region 1 - deazapurine,terpene-precursor

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Location: 392,118 - 429,633 nt. (total: 37,516 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)
deazapurine: (GTP_cyclohydroI and PTPS and QueE and QueC and not (dpdA1 or bTGT))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

C2I06_RS01825: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Hydrolases: amidase

C2I06_RS01815: amidase

smcogs: SMCOG1105: amidase

Ligases: synthetase

C2I06_RS01800: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Translocases: transporter

C2I06_RS01775: sugar-binding lipoprotein

smcogs: SMCOG1143: sugar-binding lipoprotein

C2I06_RS01920: sugar-binding lipoprotein

smcogs: SMCOG1143: sugar-binding lipoprotein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002138.2	0.20	PKS	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670
BGC0001217.5	0.20	other (other)	PreQ0 Base	Streptomyces qinglanensis
BGC0002508.2	0.18	other (other)	8-azaguanine	Streptomyces pathocidini
BGC0000802.5	0.18	saccharide	succinoglycan	Sinorhizobium meliloti
BGC0001927.4	0.18	other (other)	A-94964	Streptomyces sp.
BGC0002211.3	0.18	PKS	HEx-pks1 polyketide	Paraphaeosphaeria sporulosa
BGC0000708.5	0.17	saccharide	lividomycin	Streptomyces lividus
BGC0002354.4	0.17	other (other)	huimycin	Kutzneria albida DSM 43870
BGC0002037.3	0.16	NRPS	azetidomonamide A, azetidomonamide B	Pseudomonas aeruginosa PAO1
BGC0000689.3	0.16	saccharide	2-deoxystreptamine	Micromonospora echinospora

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001217.5	0.52	other (other)	PreQ0 Base	Streptomyces qinglanensis
BGC0002508.2	0.49	other (other)	8-azaguanine	Streptomyces pathocidini
BGC0000802.5	0.49	saccharide	succinoglycan	Sinorhizobium meliloti
BGC0002354.4	0.48	other (other)	huimycin	Kutzneria albida DSM 43870
BGC0001937.4	0.48	other (other)	tubercidin	Streptomyces tubercidicus
BGC0002306.2	0.46	ribosomal	freyrasin	Paenibacillus polymyxa ATCC 842
BGC0000881.3	0.45	other (other)	toyocamycin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001808.5	0.45	other (other)	toyocamycin	Streptomyces diastatochromogenes
BGC0000879.5	0.44	other (other)	toyocamycin, sangivamycin	Streptomyces rimosus
BGC0000640.3	0.43	terpene	carotenoid	Enterobacteriaceae bacterium DC404

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor	FPP	C15	acyclic	PP
diterpene precursor	GGPP	C20	acyclic	PP
sesterterpene precursor	GFPP	C25	acyclic	PP
triterpene precursor	HPP	C30	acyclic	PP

Genes with terpene domains:

C2I06_RS01800: PT_FPPS_like

Domain 1 (528 - 754): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: unknown

Reactions:: IPP, DMAPP → FPP; IPP, DMAPP → GGPP; IPP, DMAPP → GFPP; IPP, DMAPP → HPP

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.62 out of 23.79

Confidence: medium

MexT

Description: Global virulence regulator
Species: Pseudomonas aeruginosa PAO1
Score: 19.86 out of 21.84

Confidence: medium

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.49 out of 29.25

Confidence: medium

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 19.87 out of 20.97

Confidence: strong

ArcA

Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.18 out of 21.55

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.58 out of 27.78

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.70 out of 27.78

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.30 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.57 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.75 out of 28.19

Confidence: medium

Additional weak hits (1):

LuxO

Description: Repressor of luminescence
Species: Vibrio campbellii ATCC BAA-1116
Score: 22.66 out of 26.12

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
GFPP	Geranylfarnesyl diphosphate
GGPP	Geranylgeranyl diphosphate
HPP	Hexaprenyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
ArcA	Repressor of carbon oxidation
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
IolR	Regulator of the inositol catabolism
MexT	Global virulence regulator
MogR	Repressor of flagellar motility genes
SypG	Regulator of biofilm formation and host colonization
ZuR variant 1	Zinc-responsive repressor

NZ_CP026031.1 - Region 2 - cytokinin

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Location: 1,115,782 - 1,152,408 nt. (total: 36,627 nt) Show pHMM detection rules used

cytokinin: (IPPT and Lysine_decarbox)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

C2I06_RS05415: aldehyde oxidase and xanthine dehydrogenase

smcogs: SMCOG1293: aldehyde oxidase and xanthine dehydrogenase

Transferases: acetyltransferase aminotransferase

C2I06_RS05280: aminotransferase class V

smcogs: SMCOG1139: aminotransferase class V

C2I06_RS05355: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.4	0.36	other (other)	fatty acid enol ester, N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0002716.2	0.35	NRPS	gamexpeptide A, gamexpeptide B, gamexpeptide E, luminmide B, luminmide D, luminmide E, luminmide F, luminmide G	Photorhabdus laumondii subsp. laumondii
BGC0002362.3	0.34	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica
BGC0000466.5	0.28	NRPS	yatakemycin	Streptomyces sp. TP-A2060
BGC0000017.5	0.28	PKS, other (other)	anatoxin-a, homoanatoxin-a	[Oscillatoria] sp. PCC 6506
BGC0000310.5	0.27	NRPS	bacitracin	Bacillus licheniformis
BGC0002381.3	0.27	PKS, other (other)	tambjamine BE-18591	Streptomyces albus subsp. albus
BGC0001532.4	0.26	NRPS	bogorol A	Brevibacillus laterosporus
BGC0000209.5	0.26	PKS	chlortetracycline	Kitasatospora aureofaciens
BGC0002086.3	0.25	PKS	rosamicin	Micromonospora carbonacea

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001591.4	0.36	other (other)	fatty acid enol ester, N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0002716.2	0.35	NRPS	gamexpeptide A, gamexpeptide B, gamexpeptide E, luminmide B, luminmide D, luminmide E, luminmide F, luminmide G	Photorhabdus laumondii subsp. laumondii
BGC0002362.3	0.34	PKS	loseolamycin A1, loseolamycin A2	Micromonospora endolithica
BGC0000466.5	0.28	NRPS	yatakemycin	Streptomyces sp. TP-A2060
BGC0000017.5	0.28	PKS, other (other)	anatoxin-a, homoanatoxin-a	[Oscillatoria] sp. PCC 6506
BGC0000310.5	0.27	NRPS	bacitracin	Bacillus licheniformis
BGC0002381.3	0.27	PKS, other (other)	tambjamine BE-18591	Streptomyces albus subsp. albus
BGC0001532.4	0.26	NRPS	bogorol A	Brevibacillus laterosporus
BGC0000209.5	0.26	PKS	chlortetracycline	Kitasatospora aureofaciens
BGC0002086.3	0.25	PKS	rosamicin	Micromonospora carbonacea

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.32 out of 29.38

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 20.80 out of 26.33

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 22.63 out of 24.78

Confidence: strong

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.33 out of 24.78

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.95 out of 24.78

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 22.88 out of 26.06

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 22.26 out of 24.78

Confidence: medium

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.81 out of 24.78

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.31 out of 25.88

Confidence: medium

Additional weak hits (4):

MatP

Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.27 out of 25.75

Confidence: weak

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 24.07 out of 30.97

Confidence: weak

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.23 out of 33.73

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 23.27 out of 29.65

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
FuR variant 1	Ferric Uptake Regulator
LexA variant 2	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes
PsrA	Oleic acid responsive regulator

NZ_CP026031.1 - Region 3 - terpene-precursor

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Location: 1,874,948 - 1,895,841 nt. (total: 20,894 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: synthase synthetase

C2I06_RS09080: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

C2I06_RS09085: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002219.2	0.39	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001594.3	0.37	other (other)	fischerindole L	Fischerella muscicola UTEX 1829

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002219.2	0.39	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0001594.3	0.37	other (other)	fischerindole L	Fischerella muscicola UTEX 1829

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

C2I06_RS09085: PT_FPPS_like

Domain 1 (34 - 296): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: DMAPP, IPP → FPP

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 25.42 out of 26.06

Confidence: strong

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 22.73 out of 25.88

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.59 out of 28.19

Confidence: medium

Additional weak hits (2):

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 24.07 out of 30.97

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.79 out of 30.25

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
MogR	Repressor of flagellar motility genes
PsrA	Oleic acid responsive regulator
ZuR variant 1	Zinc-responsive repressor

NZ_CP026031.1 - Region 4 - arylpolyene

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Location: 2,489,628 - 2,530,611 nt. (total: 40,984 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxidoreductase synthase

C2I06_RS12235: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs: SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

C2I06_RS12240: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

C2I06_RS12245: dihydropteridine reductase

smcogs: SMCOG1159: dihydropteridine reductase

C2I06_RS12290: riboflavin biosynthesis protein RibD

smcogs: SMCOG1240: riboflavin biosynthesis protein RibD

Transferases: transferase

C2I06_RS12055: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

C2I06_RS12060: glucose-1-phosphate adenylyl/thymidylyltransferase

smcogs: SMCOG1064: glucose-1-phosphate adenylyl/thymidylyltransferase

Hydrolases: glucanase synthase

C2I06_RS12065: Pullulanase, type I

smcogs: SMCOG1297: Pullulanase, type I

C2I06_RS12290: riboflavin biosynthesis protein RibD

smcogs: SMCOG1240: riboflavin biosynthesis protein RibD

Lyases: decarboxylase

C2I06_RS12210: diaminopimelate decarboxylase

smcogs: SMCOG1264: diaminopimelate decarboxylase

Ligases: synthase

C2I06_RS12225: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002276.2	0.52	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000927.3	0.44	other (flavin)	roseoflavin	Streptomyces davaonensis JCM 4913
BGC0001850.4	0.42	other (shikimate-derived)	diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G	Streptomyces sp. F001
BGC0000929.3	0.42	other (other)	xanthothricin	Burkholderia glumae
BGC0002510.2	0.41	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001285.5	0.41	other (fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0002506.3	0.41	PKS	homopiloquinone, piloquinone	Streptomyces sp. FXJ8.102
BGC0002382.3	0.41	ribosomal	grimoviridin	Grimontia marina
BGC0001610.5	0.40	other (other)	gougerotin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001625.5	0.40	PKS	Isofuranonaphthoquinone A, Isofuranonaphthoquinone B, Isofuranonaphthoquinone C, Isofuranonaphthoquinone D, Isofuranonaphthoquinone E, Isofuranonaphthoquinone F	Streptomyces sp. CB01883

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002276.2	0.52	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0000927.3	0.44	other (flavin)	roseoflavin	Streptomyces davaonensis JCM 4913
BGC0001850.4	0.42	other (shikimate-derived)	diazaquinomycin A, diazaquinomycin E, diazaquinomycin F, diazaquinomycin G	Streptomyces sp. F001
BGC0000929.3	0.42	other (other)	xanthothricin	Burkholderia glumae
BGC0002510.2	0.41	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001285.5	0.41	other (fatty acid)	pseudopyronine A, pseudopyronine B	Pseudomonas putida
BGC0002506.3	0.41	PKS	homopiloquinone, piloquinone	Streptomyces sp. FXJ8.102
BGC0002382.3	0.41	ribosomal	grimoviridin	Grimontia marina
BGC0001610.5	0.40	other (other)	gougerotin	Streptomyces ahygroscopicus subsp. wuzhouensis
BGC0001625.5	0.40	PKS	Isofuranonaphthoquinone A, Isofuranonaphthoquinone B, Isofuranonaphthoquinone C, Isofuranonaphthoquinone D, Isofuranonaphthoquinone E, Isofuranonaphthoquinone F	Streptomyces sp. CB01883

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.66 out of 23.79

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 16.05 out of 18.16

Confidence: strong

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.44 out of 26.06

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.74 out of 26.06

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.47 out of 27.78

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.81 out of 27.78

Confidence: medium

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 15.94 out of 18.46

Confidence: medium

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.34 out of 26.85

Confidence: medium

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 21.32 out of 26.85

Confidence: medium

Additional weak hits (7):

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 21.04 out of 27.55

Confidence: weak

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.47 out of 26.85

Confidence: weak

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 15.78 out of 18.46

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 26.38 out of 36.54

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 24.64 out of 36.54

Confidence: weak

CelR

Description: Cellobiose uptake repressor
Species: Streptomyces coelicolor
Score: 20.62 out of 30.11

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 24.94 out of 33.14

Confidence: weak

Detailed domain annotation

Selected features only

Show module domains

TFBS Finder

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
IolR	Regulator of the inositol catabolism
MogR	Repressor of flagellar motility genes
RpoN	Regulator of nitrogen assimilation and virulence
RutR	Regulator of the pyrimidine and purine metabolism

NZ_CP026031.1 - Region 5 - lassopeptide

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Location: 3,342,644 - 3,371,422 nt. (total: 28,779 nt) Show pHMM detection rules used

lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

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MIBiG comparison

KnownClusterBlast

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TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: glycosyltransferase

C2I06_RS16035: sugar transferase

smcogs: SMCOG1146: sugar transferase

C2I06_RS16110: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

C2I06_RS16115: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

C2I06_RS16140: glycosyl transferase group 1

smcogs: SMCOG1045: glycosyl transferase group 1

Hydrolases: hydrolase

C2I06_RS16080: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Lyases: dehydratase

C2I06_RS16150: NAD-dependent epimerase/dehydratase

smcogs: SMCOG1010: NAD-dependent epimerase/dehydratase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000742.3	0.71	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000743.3	0.71	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000741.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000744.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000745.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000740.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000746.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000747.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000748.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000764.3	0.61	saccharide	exopolysaccharide	Lactococcus lactis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000742.3	0.71	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000743.3	0.71	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000741.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000744.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000745.3	0.66	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000740.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000746.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000747.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000748.3	0.64	saccharide	capsular polysaccharide	Streptococcus agalactiae
BGC0000764.3	0.61	saccharide	exopolysaccharide	Lactococcus lactis

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lasso peptide predictions

Lassopeptides - No core peptides found.

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 18.82 out of 23.79

Confidence: medium

Additional weak hits (2):

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 26.08 out of 31.73

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 24.95 out of 35.63

Confidence: weak

Lasso peptides

RREFinder

TFBS Finder

Core peptide predictions

No core peptides found.

RRE predictions

: RRE type: Stand_Alone_Lasso_RRE; Location: 12 - 96; Score: 86.6; RRE type: Stand_Alone_Lasso_RRE; Location: 10 - 94; Score: 61.0; RRE type: Streptide_RRE; Location: 25 - 88; Score: 28.1

TFBS definitions

Regulator	Description
IolR	Regulator of the inositol catabolism

NZ_CP026031.1 - Region 6 - terpene

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Location: 4,235,044 - 4,256,939 nt. (total: 21,896 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

C2I06_RS20385: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000888.5	0.35	other (other)	bacilysin	Bacillus sp. CS93
BGC0001184.4	0.33	other (other)	bacilysin	Bacillus velezensis FZB42
BGC0001197.5	0.30	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000663.5	0.30	terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001626.3	0.27	PKS	isoindolinone	Stachybotrys chlorohalonata IBT 40285
BGC0000204.5	0.27	PKS	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000188.5	0.26	other (other)	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0002212.3	0.26	PKS	Orsellinic acid	Moniliophthora roreri MCA 2997
BGC0002506.3	0.25	PKS	homopiloquinone, piloquinone	Streptomyces sp. FXJ8.102
BGC0002278.3	0.24	NRPS, other (other)	brasiliamide I, brasiliamide A, brasiliamide B, 2,2-dibenzylpiperazine, brasiliamide D	Penicillium brasilianum

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000888.5	0.35	other (other)	bacilysin	Bacillus sp. CS93
BGC0001184.4	0.33	other (other)	bacilysin	Bacillus velezensis FZB42
BGC0001197.5	0.30	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000663.5	0.30	terpene	hopene	Streptomyces coelicolor A3(2)
BGC0001626.3	0.27	PKS	isoindolinone	Stachybotrys chlorohalonata IBT 40285
BGC0000204.5	0.27	PKS	benastatin A, benastatin B, BE-43767, TAN1532B	Streptomyces sp. A2991200
BGC0000188.5	0.26	other (other)	saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2	Cylindrospermopsis raciborskii T3
BGC0002212.3	0.26	PKS	Orsellinic acid	Moniliophthora roreri MCA 2997
BGC0002506.3	0.25	PKS	homopiloquinone, piloquinone	Streptomyces sp. FXJ8.102
BGC0002278.3	0.24	NRPS, other (other)	brasiliamide I, brasiliamide A, brasiliamide B, 2,2-dibenzylpiperazine, brasiliamide D	Penicillium brasilianum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	hopanoid		C30	hopanoid skeleton	unknown
triterpene	polypodane		C30	polypodane skeleton	unknown

Genes with terpene domains:

C2I06_RS20415: T2TS

Domain 1 (5 - 624): Type 2 terpene synthase

Subtype: Squalene substrate

Reactions:: squalene → hopanoid; squalene → polypodane

Transcription Factor Binding Sites

Binding sites found:

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 23.44 out of 30.25

Confidence: medium

Additional weak hits (3):

CopR

Description: Copper-responsive regulator
Species: Lactococcus lactis subsp. lactis Il1403
Score: 23.71 out of 30.97

Confidence: weak

CsoR

Description: Copper-responsive repressor
Species: Streptomyces lividans
Score: 20.19 out of 32.38

Confidence: weak

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.19 out of 26.85

Confidence: weak

Terpene

TFBS Finder

Glossary

No acronyms to display

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator

NZ_CP026031.1 - Region 7 - cyclic-lactone-autoinducer,lanthipeptide-class-iii

Download region GenBank file

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Location: 4,603,731 - 4,631,654 nt. (total: 27,924 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)
lanthipeptide-class-iii: (micKC and not PKS_KS)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: aminotransferase

C2I06_RS22045: aminotransferase

smcogs: SMCOG1019: aminotransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002700.2	0.38	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0002111.3	0.34	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000551.5	0.32	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000501.3	0.31	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000496.5	0.31	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000513.3	0.31	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000553.3	0.29	ribosomal	SRO15-2212	Streptomyces filamentosus NRRL 15998
BGC0002458.3	0.25	NRPS	alazopeptin	Streptacidiphilus griseoplanus
BGC0000546.3	0.24	ribosomal	SAL-2242	Streptomyces albidoflavus
BGC0002701.2	0.23	ribosomal	paenithipeptin	Paenibacillus thiaminolyticus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002700.2	0.53	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0002111.3	0.50	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0000513.3	0.49	ribosomal	Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3	Saccharopolyspora erythraea NRRL 2338
BGC0000496.5	0.48	ribosomal	AmfS	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000551.5	0.48	ribosomal	SapB	Streptomyces coelicolor A3(2)
BGC0000501.3	0.48	ribosomal	catenulipeptin	Catenulispora acidiphila DSM 44928
BGC0000553.3	0.46	ribosomal	SRO15-2212	Streptomyces filamentosus NRRL 15998
BGC0000546.3	0.43	ribosomal	SAL-2242	Streptomyces albidoflavus
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000500.5	0.43	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for C2I06_RS22105

C2I06_RS25335

Leader:

MKNVLGLQKIDKKERKNGDVLK

Core:

SSVSLGCSPSSNTSWFFC

Core with dehydrations:

DhaDhaVDhaLGCysDhaPDhaDhaNDhbDhaWFFCys

antiSMASH-DB 4.0 matches for C2I06_RS25335

100.0%

NZ_CP026031.1and 4 others:

NZ_CP026033.1 Lanthipeptides: C2H98_RS25970_lanthipeptideNZ_CP026040.1 Lanthipeptides: C2I17_RS08935_lanthipeptideNZ_CP053315.1 Lanthipeptides: HLK66_RS26225_lanthipeptideNZ_CP053989.1 Lanthipeptides: FOC77_RS25275_lanthipeptide

Lanthipeptides: C2I06_RS25335_lanthipeptide

1

SSVSLGCSPSSNTSWFFC

18

SSVSLGCSPSSNTSWFFC

1

SSVSLGCSPSSNTSWFFC

18

84.2%

NZ_CP024036.1:

Lanthipeptides: CR091_RS27895_lanthipeptide

1

SSVSLGCSPSSNTSWFFC

18

SS+SLGCSPSSNTSWF C

2

SSLSLGCSPSSNTSWFLC

19

62.5%

NZ_PIZP01000004.1:

Lanthipeptides: CW747_RS14930_lanthipeptide

1

SSVSLGCSPSSNTSWFFC

18

SS S GC+PSSNTSWFFC

7

SSASWGCAPSSNTSWFFC

24

with 6 more sequence matches

45.0%

NZ_AXVK01000021.1:

Lanthipeptides: K332_RS23900_lanthipeptide

1

SSVSLGCSPSSNTSWFFC

18

SSVS+ C S S+F C

3

SSVSVNCKVISTISFFLC

20

45.0%

NZ_JAMYIV010000006.1:

Lanthipeptides: allorf_139780_139899_lanthipeptide

1

SSVSLGCSPSSNTSWFFC

18

SS S+ C S S FFC

3

SSASINCKRKSTLSLFFC

20

31.6%

NZ_CP017429.1:

Lanthipeptides: BI282_RS13940_lanthipeptide

3

VSLGCSPSSNTSWFFC

18

+S+ C S+ S F C

1

ISIACKKKSSISAFSC

16

31.6%

NZ_CP084585.1:

Lanthipeptides: allorf_0614669_0614794_lanthipeptide

11

SNTSWFFC

18

S TSWF C

12

STTSWFLC

19

27.3%

NZ_BMMN01000011.1and 19 others:

NZ_FTNI01000016.1 Lanthipeptides: BXA11_RS42310_lanthipeptideNZ_JABBWU010000019.1 Lanthipeptides: HHX30_RS29855_lanthipeptideNZ_JABBWU010000019.1 Lanthipeptides: HHX30_RS29860_lanthipeptideNZ_JABBWU010000019.1 Lanthipeptides: HHX30_RS29850_lanthipeptideNZ_JABBWV010000002.1 Lanthipeptides: HHX31_RS05740_lanthipeptideNZ_JABBWV010000002.1 Lanthipeptides: HHX31_RS05735_lanthipeptideNZ_JABBWX010000013.1 Lanthipeptides: HHX35_RS30140_lanthipeptideNZ_JABBWX010000013.1 Lanthipeptides: HHX35_RS30145_lanthipeptideNZ_JABBWY010000006.1 Lanthipeptides: HHX37_RS18535_lanthipeptideNZ_JABBWZ010000004.1 Lanthipeptides: HHX40_RS12965_lanthipeptideNZ_JABBXA010000003.1 Lanthipeptides: HHX41_RS08065_lanthipeptideNZ_JABBXA010000003.1 Lanthipeptides: HHX41_RS08060_lanthipeptideNZ_JABBXA010000003.1 Lanthipeptides: HHX41_RS08055_lanthipeptideNZ_KI866522.1 Lanthipeptides: MPTA5024_RS40525_lanthipeptideNZ_QOIL01000022.1 Lanthipeptides: DQ384_RS31190_lanthipeptideNZ_QOIL01000022.1 Lanthipeptides: DQ384_RS31185_lanthipeptideNZ_VANP01000005.1 Lanthipeptides: FED44_RS16255_lanthipeptideNZ_VYTZ01000006.1 Lanthipeptides: F5972_RS17720_lanthipeptideNZ_VYTZ01000006.1 Lanthipeptides: F5972_RS17715_lanthipeptide

Lanthipeptides: IEY80_RS26010_lanthipeptide

5

LGCSPSSNTSW

15

LGC+P N+S

7

LGCTPHENSSL

17

16.1%

NZ_GG667191.1and 1 other:

NZ_GG667191.1 Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

Lanthipeptides: HMPREF0298_RS11685_lanthipeptide

7

CSPSSNTSWFFC

18

C+P T W C

7

CTPGCITGWMMC

18

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (2):

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 23.21 out of 35.63

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.59 out of 22.40

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

C2I06_RS25335 - Class III

Cleavage pHMM score: 2.60

RODEO score: 0

Monoisotopic mass: 1750.8 Da

Molecular weight: 1751.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 1769.9 Da N = 1; 1787.9 Da N = 2; 1806.0 Da N = 3; 1824.0 Da N = 4; 1842.0 Da N = 5; 1860.0 Da N = 6

TFBS definitions

Regulator	Description

NZ_CP026031.1 - Region 8 - triceptide

Download region GenBank file

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Location: 5,034,292 - 5,055,521 nt. (total: 21,230 nt) Show pHMM detection rules used

triceptide: ((cds(PF04055 and (TIGR04085 or SPASM)) and triceptide_precursor) or triceptide_rSAM)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

C2I06_RS24115: aldo/keto reductase family oxidoreductase

smcogs: SMCOG1039: aldo/keto reductase family oxidoreductase

Transferases: phosphotransferase

C2I06_RS24135: Glucose-specific phosphotransferase enzyme IIA

smcogs: SMCOG1145: Glucose-specific phosphotransferase enzyme IIA

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000929.3	0.35	other (other)	xanthothricin	Burkholderia glumae
BGC0001959.4	0.34	other (other)	taylorflavin A, taylorflavin B	Streptomyces hiroshimensis
BGC0002152.2	0.34	other (other)	toxoflavin	Pseudomonas protegens Pf-5
BGC0001972.4	0.33	other (other)	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0001768.4	0.33	NRPS	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001578.3	0.31	PKS	duclauxin	Talaromyces stipitatus ATCC 10500
BGC0000843.5	0.31	other (non-nrp beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0001556.5	0.31	NRPS, PKS	combamide	Streptomyces sp.
BGC0000723.5	0.28	other (cyclitol), saccharide	validamycin A	Streptomyces hygroscopicus subsp. limoneus
BGC0001657.4	0.27	NRPS	lysocin	Lysobacter sp. RH2180-5

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000929.3	0.35	other (other)	xanthothricin	Burkholderia glumae
BGC0001959.4	0.34	other (other)	taylorflavin A, taylorflavin B	Streptomyces hiroshimensis
BGC0002152.2	0.34	other (other)	toxoflavin	Pseudomonas protegens Pf-5
BGC0001972.4	0.33	other (other)	toxoflavin, fervenulin	Streptomyces hiroshimensis
BGC0001768.4	0.33	NRPS	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001578.3	0.31	PKS	duclauxin	Talaromyces stipitatus ATCC 10500
BGC0000843.5	0.31	other (non-nrp beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0001556.5	0.31	NRPS, PKS	combamide	Streptomyces sp.
BGC0000723.5	0.28	other (cyclitol), saccharide	validamycin A	Streptomyces hygroscopicus subsp. limoneus
BGC0001657.4	0.27	NRPS	lysocin	Lysobacter sp. RH2180-5

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.55 out of 18.46

Confidence: strong

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.86 out of 23.79

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.54 out of 27.78

Confidence: strong

Additional weak hits (1):

DasR

Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 20.14 out of 27.04

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
IolR	Regulator of the inositol catabolism
RpoN	Regulator of nitrogen assimilation and virulence
ToxT	Regulator of MSHA biosynthesis