LOCUS       NZ_RIAS01000007        21627 bp    DNA     linear   CON 13-MAY-2024
DEFINITION  Paenibacillus amylolyticus strain 27C64
            NODE_7_length_325177_cov_22.9038_ID_13, whole genome shotgun
            sequence.
ACCESSION   NZ_RIAS01000007
VERSION     NZ_RIAS01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus amylolyticus
  ORGANISM  Paenibacillus amylolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 325177)
  AUTHORS   Keggi,C. and Doran-Peterson,J.
  TITLE     Paenibacillus amylolyticus 27C64 has a diverse set of
            carbohydrate-active enzymes and complete pectin deconstruction
            system
  JOURNAL   J Ind Microbiol Biotechnol 46 (1), 1-11 (2019)
   PUBMED   30377865
REFERENCE   2  (bases 1 to 325177)
  AUTHORS   Keggi,C. and Doran-Peterson,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-OCT-2018) Microbiology, University of Georgia, 120
            Cedar St, Athens, GA 30602, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-MAR-2015
            Assembly Method                   :: SPAdes v. MARCH-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 93.0x
            Sequencing Technology             :: Illumina NextSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003719335.1-RS_2024_05_13
            Annotation Date                   :: 05/13/2024 02:42:13
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,967
            CDSs (total)                      :: 5,826
            Genes (coding)                    :: 5,778
            CDSs (with protein)               :: 5,778
            Genes (RNA)                       :: 141
            rRNAs                             :: 5, 10, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 10, 9 (16S, 23S)
            tRNAs                             :: 113
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 8 of 48
            Pseudo Genes (incomplete)         :: 39 of 48
            Pseudo Genes (internal stop)      :: 7 of 48
            Pseudo Genes (multiple problems)  :: 6 of 48
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:46:40
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 229202
            Orig. end                         :: 250829
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RIAS01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21627
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="2"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21627
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21627
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11627](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11627
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            complement(218..841)
                     /locus_tag="EC604_RS14805"
                     /old_locus_tag="EC604_14710"
     CDS             complement(218..841)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020618896.1"
                     /locus_tag="EC604_RS14805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14710"
                     /product="GNAT family protein"
                     /protein_id="WP_123064894.1"
                     /transl_table=11
                     /translation="MQTIETDRLILRNFTATDATGLIEYTANPRVNCFMDHQMSTLEEA
                     IAEVEKRSKDDSHIAVCLKDSNEIIGELFGMTEGHDPDSDPDSKSNSDPKSDSDTYSIG
                     WNFNGRFEGKGYASESARAFMEYLFMEQGIRRIYAYVEDDNFRSQKLCEKLGMRREGLF
                     LEFISFVKNEDGTPKYENTYQYAILKKEWLAQYAPTCMMSRCKP"
     gene            complement(950..1771)
                     /locus_tag="EC604_RS14810"
                     /old_locus_tag="EC604_14715"
     CDS             complement(950..1771)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017690628.1"
                     /locus_tag="EC604_RS14810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14715"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_123064895.1"
                     /transl_table=11
                     /translation="MPKFSKRTVMKILLGLLAALSTGLLIYYAPAIIRIMSSMDNFRAY
                     IHSTGHWGPIMFILFQILQIVVAPIPGEIVQIAGGYIYGSALGSFYTTVGLVLGSAIAF
                     YFTRFIGRDFVSRLLQKQNMKWMSFMHDERKLTAFLFIFFLIPGLPKDMLVFVAALTSI
                     SSLRFFTILLVGRLPWIIASAAVGSNLHMQQYTIAIIISVIAVVGFIFGYIYKDKLINL
                     FSKADKTNQTNETTEVSEIKEINETKEVNTTFKTKAAPALVKPRDLAPKKG"
     gene            1932..2630
                     /locus_tag="EC604_RS14815"
                     /old_locus_tag="EC604_14720"
     CDS             1932..2630
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312091.1"
                     /locus_tag="EC604_RS14815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14720"
                     /product="response regulator transcription factor"
                     /protein_id="WP_123064896.1"
                     /transl_table=11
                     /translation="MNNNKQILIADDNSEIREIVKILLESENYEVIEAVDGQDAIDKVT
                     QETDLIILDMMMPNKSGLKACLEIREKTSAPILFLTAKTQDSDKQLAFSSGSDDFLSKP
                     FSYTELVARVKALLRRYYVYRGKEKVEEAEHIAVKDLTIHKDAKSVYIGEKEISLTEIE
                     YQILLLLASKRRKVFSAENIYESVWQQPYFYTCNNTVMVHIRNLRNKLEDDPQHPKYVQ
                     TVWGKGYKIE"
     gene            2623..3960
                     /locus_tag="EC604_RS14820"
                     /old_locus_tag="EC604_14725"
     CDS             2623..3960
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012722.4"
                     /locus_tag="EC604_RS14820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14725"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_161556947.1"
                     /transl_table=11
                     /translation="MNKLLIGKKLKLKLVLAIILSLFVAVGTFIVLQVVGETALDSYLS
                     KSTFSENRQQDALERFQTMVSSEHLSTQDHQRLSEWIRGERYLELFMFEQDKLIYSSNI
                     QADSAINEELLTQFLPSRTPITTVQFTDKTVQIYLVGFYEYQYYNLLLILTVFAALIAF
                     IVAFLLMINRKISYIGNLEREIKILEGGNLDYKITVSGKDELSSLAMSIDEMRKSFVER
                     LGSEERVRSANRELITAISHDLRTPLTILLGYMDIIELGKYKTQEDLHQYIHNSREKAY
                     QIKILSDKLFEYFTVSTASEEGDVEFEIYDGRELFDQLLDEQLALMENFDVEMKQQYGE
                     RAFLIELNLVAIRRVFDNIFSNIKKYAHTSYPVHIELFFHQQTLIMTARNRIKPVDKTK
                     DSNEIGLVSCQKIIEQHNGTLKISQAADTFILQIELPVILSKEDQK"
     gene            4156..7536
                     /locus_tag="EC604_RS14825"
                     /old_locus_tag="EC604_14730"
     CDS             4156..7536
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020618956.1"
                     /locus_tag="EC604_RS14825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14730"
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_240036901.1"
                     /transl_table=11
                     /translation="MKNNHTPLSKNRVLEELDSLGYSNRMKEIARLGRNHLAVAPKEYA
                     ALLIQLLDSGTAYEAHLALTGAGAVKDAQAVIHALNHSKAGVRGRAAWMLAEVVIDPGY
                     NIESEIVSMSHHCRQQLLRSIVKYARQDWAERLLPIVLERWGADEAVFLLSMCGEATVR
                     TRLPQLGYAIDNWRVITTRYPDLVAAYLENALNQASESDRPSVWYEMSTAVEKLSIVRP
                     AVVLEYALSYGPKEQIHPVIKNQLGILIRTSPEQVFELLTRQETRAYLLNNGVPAGVLK
                     KRRYFTTAHWTAMVTMLAEAPFQVAKVLDTLAPSSREALFNAAYPEQERTNRVFPMTLL
                     DVLPHQLRDKEAVRMLNLREVKEDRGRTFDMTARRLIIQVRETLEQSVQVSNADERATA
                     YSRLIQSTALSRSGMEETIRFLTRVKNDQDPVRFIVMAELSRCPVTMFKEEHVPHLTIL
                     VDSVIEARDTSHGTRTAVEQLAFTVLREHANEPERPLFQFALRTLKRMAMRDGQFMLFS
                     REWESLPQAALETLFEEIYAMGIEANKRESDYVVLQMASAFGKAIDRLPKLHDLLEELV
                     KGKKSAAQAVRYWLAPYKTRDKRVRELLDLDPTFISFYEVFEHLHLKRQEWLDPFISGK
                     VLKGKHLTGKTIYLVPAYNGFYRWLPRQQQALASLLDRVAQDNKRSFYERANAMRSLAG
                     MPDYRSNQPLEKLLTDPEVHIVEAALHAFSLTEEPEEALPVLLNNLDGDRARVAMYSIP
                     RCARRVNPVLLTSMLSDLLDREKLKITVRKEAVRLLGAYKIRESVTLLVREFEKPNRHK
                     DVIIAIGHAARQCLDDERSWAMMSVMASSSDRDIARSLLNQRPDELPVEARQRYLQWIT
                     EIAGHDDPIVSMEAFHAMSRWGKVSAEVIADCAGTALSNLQEGTRWKSALHAFVTVCKD
                     GKVNDRVMQVTRELAQAKVEDDWNAGSERDLPHRQRLHQLIDSLVSLSPLVKRKLAPLY
                     AAMIETLQQHEMLKLTVIRLHLAAMDWSQPDQVITRLYPVIDVANANPVVLNSVDRQVT
                     RTVLDSKGYWNPEHLLHIVDVLRARADITSSWIGLSLLKIAGEELLWNQDCRERLRAYR
                     QHEQEAVRLLALDSWTILE"
     gene            complement(7623..8114)
                     /locus_tag="EC604_RS14830"
                     /old_locus_tag="EC604_14735"
     CDS             complement(7623..8114)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EC604_RS14830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EC604_14735"
                     /product="hypothetical protein"
                     /protein_id="WP_123064898.1"
                     /transl_table=11
                     /translation="MKEIAFMLSFLMYTFTTLMFYSGAGSDVSPAVSIQDEPPSSAWEE
                     QIDQIANNQQSPKEKAAAVEKLAKEYVPTTEELEEFKVYVLNEFLNLRYLDDSSDDKYM
                     LSGIFQAIALKHHDLDRLRDLAEAFYHNTKNVYTGVTKPGSDSVLKYEEQMFESINAGR
                     "
     misc_feature    8230..8247
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            8331..9407
                     /locus_tag="EC604_RS14835"
                     /old_locus_tag="EC604_14740"
     CDS             8331..9407
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /locus_tag="EC604_RS14835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14740"
                     /product="glycosyltransferase"
                     /protein_id="WP_161556948.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 8.4e-34,
                     bitscore: 110.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVFVVDIVLSGRGGMETALSLIYHELKQKHDITVILRGESADD
                     AWEEGINTITLSAKINDFIPKHILFNMYSAALANVMKDLPRADIIVSTGAIGVKASTMA
                     VKRLDIQVPVVSWLHFNLDFYYQFFEDLRAADGHLAISEGNLRDLNCVFPEKQNKLVYN
                     PVKFDNIPYVNRAPHPVFLVVGRLAKVKNVDQILRAFSPLQKEYFELHIIGDGNQYESL
                     VELSRQLGLQNHVVWYGWQPRPWDTVISATSLVLASDTEPFGLVLIEALARGIPVISSN
                     CKYGPGEIINDSNGWLYEPDNLKQLTSILDGVMQGRLPLPAPELCRESVRSYAVQSIAE
                     RFEQALQDIENDQAIQQK"
     misc_feature    9419..9433
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.65"
                     /tool="antismash"
     misc_feature    complement(9424..9433)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    9992..10005
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.06"
                     /tool="antismash"
     gene            10001..11359
                     /locus_tag="EC604_RS14840"
                     /old_locus_tag="EC604_14745"
     CDS             10001..11359
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="EC604_RS14840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14745"
                     /product="radical SAM protein"
                     /protein_id="WP_161556949.1"
                     /sec_met_domain="QueE (E-value: 3.2e-14, bitscore: 46.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 6.1e-47, bitscore:
                     154.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.9e-12, bitscore: 39.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.7e-25, bitscore: 81.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.2e-18, bitscore:
                     58.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.5e-11, bitscore: 37.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMEERLHIPDVAVYYEDGQYVVHNVQLNCWVVYSPSEYEIASEL
                     IYDGKSATELIDSGLNPQQVKQVARKMLMYRVAYQGERPAEYHMLDVMQKQGMGKVPPA
                     AVYFVTTYKCNLSCIYCYADSSPERSMNGDMNTEEAKDMIRQIKELGSSTIVFTGGEAF
                     IRKDIMELMAYSKEIGLRVNVISNGTLINSREKVNEIAKLVDVFTISFDSLDKEEHEAN
                     RGINTWERARKSIDLILEAGIKLKINQTVTKHNRDSVEPMLQFATERSVRLNIVPLATL
                     GRGDDRMQGLNFGERRRIADRMLDIEMGDAHEDCHALNVRQYERRRHCGHGTSEFSIDA
                     KGNVFPCKLMHSPMFHAGSIREKSLREIWETSEVFERSRNRTVHTLPECMKCTFRESCG
                     GGCRAFHWGATGDIDGTTPHDCSGIRRGIRRKMVAYFKMAGGKPNEPVVSNSR"
     gene            11331..11627
                     /locus_tag="EC604_RS14845"
                     /old_locus_tag="EC604_14750"
     CDS             11331..11627
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="EC604_RS14845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14750"
                     /product="PqqD family protein"
                     /protein_id="WP_123064901.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.7e-08,
                     bitscore: 26.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.5e-08, bitscore: 28.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQWFQIADDVFFDENVEGIFILSDAGEVFVLEDDVSKAVWNMLA
                     DSAQSLDEMCQQIKLKFNIGDEDHVEDDVRDFVTALSKIGVLNECLVPADRIS"
     aSDomain        11346..11591
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_EC604_RS14845_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="7.70E-09"
                     /identifier="RREFam002.1"
                     /label="EC604_RS14845"
                     /locus_tag="EC604_RS14845"
                     /protein_end="87"
                     /protein_start="5"
                     /score="26.5"
                     /tool="antismash"
                     /translation="QIADDVFFDENVEGIFILSDAGEVFVLEDDVSKAVWNMLADSAQS
                     LDEMCQQIKLKFNIGDEDHVEDDVRDFVTALSKIGVL"
     gene            11597..12373
                     /locus_tag="EC604_RS14850"
                     /old_locus_tag="EC604_14755"
     CDS             11597..12373
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EC604_RS14850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EC604_14755"
                     /product="S24/S26 family peptidase"
                     /protein_id="WP_123064902.1"
                     /transl_table=11
                     /translation="MLSTRRQDFLIRALQQGKSIPIVIEGHCMHPLLVEGQHITVHPLL
                     EDIKVGDIVLVRDQMKGFLAHRIISLGHDFVVTSGDRNHMSDPPVRRNDILGRLDVPEN
                     PMLNQNPEQNPDQRSSTLTDLQGLSCEIKIVVHPDAIDSSYGEVLSRAFGIDVDIAENP
                     LTQLKHMREKGWTSVVIHEGARQHLSQLPHVASRVVIFAGYEVARDTDESAGIIGMSDV
                     DFVARTAVEYWNNLHAELSIAAIIGFHMRGTTVCHG"
     gene            12361..12603
                     /locus_tag="EC604_RS14855"
                     /old_locus_tag="EC604_14760"
     CDS             12361..12603
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024247.4"
                     /locus_tag="EC604_RS14855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14760"
                     /product="4Fe-4S binding protein"
                     /protein_id="WP_123064903.1"
                     /transl_table=11
                     /translation="MSWVITATCEGELLAKCIVACPEEAIQTSPDAKQYYINPSVCTDC
                     GLCDLACPVAAIFPESAVPKQWRSSIEENRLFFLT"
     gene            12694..13983
                     /locus_tag="EC604_RS14860"
                     /old_locus_tag="EC604_14765"
     CDS             12694..13983
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="EC604_RS14860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="EC604_14765"
                     /product="hypothetical protein"
                     /protein_id="WP_123064904.1"
                     /transl_table=11
                     /translation="MPTLRVRVGQYPLLLELCRAINELRQDKLWTVPKERNYPPALLNL
                     IRNRGLRSNVYRYWGSLLLKDMLAVQSEPEVKLVKRILSASADTKADEVMAEYESHLAS
                     QCEAIREYLAPLIQNFDIAEVVELKLYPLSTMPPPQIGRFGASLSKATTTSVHLAFGAP
                     PLHLWDDFNLTVSFFARGGIHYLVKEWLLAHEGEYGEVKEGLKPYLINLVSAIILMEVD
                     HFFSTNFDLVFHEEDKLVYQWALSQYDGKMGFGNHLIQYVRNLNADWPPPHLGDVRHDV
                     PMTVVHTIQKKVRVSISDQYNLLANTRWIADYYDIAEAEDDGGLGRAYPFLVLPWNAEG
                     AAEICSRHHIQHSYHEAAVTYEHMTGQKQFDTTDTLCLLIDDDAESSWKFVLLCPSART
                     GSGYYIETSVLSQIHTAIAFVDSASGRRIL"
     gene            13980..15824
                     /locus_tag="EC604_RS14865"
                     /old_locus_tag="EC604_14770"
     CDS             13980..15824
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="EC604_RS14865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14770"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_123064905.1"
                     /transl_table=11
                     /translation="MSRLQAGLVQMWMIVRAGDRAIWVLLALILALGVWPGFMVWAIKH
                     SVNQLANGDRNASLAYIGIIAGAGTIAILLNVIQPYFLRKVKDHVYHNLSIRLFDNVNR
                     RTENELLRASTRNRISSTSESVSSIYHGGLDGLSALLQVIITGFSLTWILLVVAWWAPL
                     LILAGTVLNVWLMKKAAATESDFLQSISEKTRLEGTFLDMLTTLKSAKEMRVFGISGWV
                     KDKWQTEQIRIAQLTIRQMIKTGFYRLAGQLGSGVVTTIVLLAGLWKLWQGTLHPGEVA
                     ALLIGGLHLEQLLGLVLSQGKHWLGRKMFLAELIQQPAEEQSKTVANPVTETVANTAVA
                     KSTNITPYAGMDTGTVGCQNNDIHSTCAISVRQLTFSYDGDHDVLKNINFDIERGARVA
                     IVGANGSGKSTLMLMLAGLLKPDHGFVVSEDTGGFCLQDYGRYKLSAAENVYLGDITRK
                     EHTEDIMEALKLTNAQFVNTLPQGLQTELWPEVGGSDLSEGQWQRLALARSMFRAIYRA
                     GSVIIMDEPTSKLDPSNELSILESIINRLEGYTVLFVVHRLVGCAFADTVLLMDQGEIR
                     DYGTHDGLLQTSEPYQAMWKASSSFMETMKEEEGGDVA"
     gene            15824..17533
                     /locus_tag="EC604_RS14870"
                     /old_locus_tag="EC604_14775"
     CDS             15824..17533
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="EC604_RS14870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14775"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_123064906.1"
                     /transl_table=11
                     /translation="MWLTKVKNKRKLLPWIAFALSVTLFKGILPAVRIFLFGYAVQQVI
                     SGVDLDRMILLMAWFAAATIGEKVMDSLYGIALEGLRVHMGRAAKELYIDQYNKVPYQK
                     LLDASFSESAEKAANGLDRGHRVLTLALDVLSAAVTLISLGTALWFVTKIGCLVMMVTF
                     AFVVIKQYKLGRQMFNIENQLSGQRIRENYYRSTVMDFQLGKERKLFGYSPYIVGLWKN
                     TFTDISKTNQSFLLTSQKTSGLMQIGQLLLISVAYMVSILTASSSIGGLIIAFQLIDEL
                     LGKANAFVLELRMFTSELLTASNLSRFLAKDTADQVETPAKEANNEIELNGVGFSYPNH
                     SNPVLTDVTMHFRTGELVGLVGENGAGKTTLCNLICGLLEPAEGEIWVDGKPSLHTDRL
                     RSVSVAYADFSRFPLSVQQNVGLHQKWSDVAQQLVQDIIERSGDKRLGAGYTDGTELSG
                     GQWQRVAVARAMANTRTMLILDEPTAAMDPVMEESVVRSVKQFAAQGKAALLIAHRVST
                     VMHCDRVYVMADGQIVQEGAPLRLLEEDGVFRDMYGAQVALLRKQGMAASVG"
     gene            17565..18572
                     /locus_tag="EC604_RS14875"
                     /old_locus_tag="EC604_14780"
     CDS             17565..18572
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016027.4"
                     /locus_tag="EC604_RS14875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14780"
                     /product="glycosyltransferase"
                     /protein_id="WP_123064907.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 2.6e-13,
                     bitscore: 43.9, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLVVSRGNGFGHAKRDLLVAQRLIQFNHEVIIASYSSGFQYLQ
                     RVYSGQLIDLELPSAGSSAERTLKLLDLIRRTQPDGIVVDEELLVLPLAKSLGIPTCFI
                     TNWLEDEQETLGYLHMADRIAIVDQLEHWMFPTSDSIREKLHFVGPVVEVPERAAAREK
                     KIVITSGSATIVDVPFFKKAIADLKGETDYIKLVYSGTLTKSLQRLGDETTQFIADPSS
                     FMDKVRDSSLVVCRGGHTTLWELASLGIPAIAVPRREEVNRSNIVYARQMGERGYIRWL
                     EESDMDQGLIAAYAREILRGETQLQTYAYDGAALDHLTSCILESFSLQLAEKPL"
     gene            18569..19987
                     /locus_tag="EC604_RS14880"
                     /old_locus_tag="EC604_14785"
     CDS             18569..19987
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="EC604_RS14880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14785"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_123064908.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.4e-20,
                     bitscore: 66.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVTVIIPVYGKPDVLHLTLQALAGQHYSDFSVWLVDQGGTIPFE
                     QFRNAYEDKLRIHYIDTPAHTTVSDKRNRAIRESAEDVVIFLDADTIVCADFVGEHMAL
                     QCAGNEVVIGYIYGKKGMQREELNYEGKLEFEAFMRWFEHESRHIPDEREKYYEPVQDQ
                     LMRLQWPWAVFWSGNISVSRAALQRAGGFDHRFKGWGIEDIEVGYRLVQSGYELTLSRS
                     AWAVHVPHEVDEAKRMQDQTANARMFLRKYPAMEIELYFLKVHDWRKVPDRGEAIAKAA
                     NKATVTATTSIADTLMQEDELTHGMQKIIQMVTSSYDTHFLLVGYDAKLFVLSQVSTLI
                     DPRAMSEGLMNVSGKKVYRLAGSCMPFEALSFDVCIITPVWTMYNPEMIPHLLMEALRT
                     SRVCYCLSPRTEILPLLAVLTSLKKLGRDIEYSIVDVVDQNMKLITCKDRGMIQVQEGG
                     MLDDQGRYRHHSYI"
     gene            19950..21302
                     /locus_tag="EC604_RS14885"
                     /old_locus_tag="EC604_14790"
     CDS             19950..21302
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF025025.4"
                     /locus_tag="EC604_RS14885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EC604_14790"
                     /product="glycosyltransferase"
                     /protein_id="WP_123064909.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.6e-24,
                     bitscore: 79.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKGVTVIIPTYNHSDLLERTLVCLKHQEADISLFEVIVCDDGSS
                     DDTKEVACSFESDLDLRYCYQKDLGFRAGTARNMGLHLAKHEICVYLDTGVLIGADLIL
                     NVIQFHDLHEHTIGLGTVHGMNQKDHQHPLAKYLQSIASSEHPEACLRNPMLKAYPDSR
                     QTQFDFYENDLDRSSAPWSMFWTSMVSVETFLLRQVGGFDESFHGWGHEDLELGYRLWK
                     AGLHFRSDPSLRALHLPHEQFNPVQMTSRKNHLHFVKLHQELPVELSYVNENFIFEMLL
                     GQLNVADQYLPQNYDDLDPNLLGSHEEGRRLAVGYITPAFASRLNITDVFACNQRNAEI
                     IRTQRPDVHTAFKAGFVNFCEDNMYQTVIITDVWKVIPITLLIVLLDDMLRIAKRVYLL
                     DTADLELDKLPIVGELLPTGFHAESIASAGKTEVYAITRLVQQLHVEVNNL"
ORIGIN
        1 aatggaacga tgtttgtagc cgatgcggta gtgatcgcca ctccagcgta tgcggcagca
       61 gatatgcttg cacatgacca taagtcgatt gcagaacacc tgcgttcgat cccgtatgct
      121 tcggtgatga acgtcgtact ggcttatcgc gagcaggatg tgggcgtttc cctgaattca
      181 tccggttttg ttgtaccgcg taaagaagaa cgcaaaatta cggcttgcac ctggacatca
      241 tgcaagtggg agcatactgc gccagccatt ctttttttaa tatcgcatat tgatacgtgt
      301 tttcgtattt tggcgtgccg tcttcatttt tgacaaaaga aataaactca agaaatagcc
      361 cttcccggcg catgccgagt ttctcacaca gcttctgaga ccggaagtta tcgtcttcca
      421 cataagcata gattcgccga attccctgtt ccataaaaag gtattccatg aaggcacgag
      481 cactctcact ggcgtatcct ttcccctcaa accttccgtt aaaattccag ccgatactat
      541 acgtatctga atctgacttt ggatctgaat tcgatttcga gtctggatct gaatctggat
      601 catggccctc tgtcatacca aacagctctc caatgatttc attgctgtct ttcagacaaa
      661 cggcgatatg ggagtcgtcc ttgcttcgtt tctctacctc tgcaattgct tcctcaagtg
      721 tcgacatctg atgatccata aagcagttca ctcgtggatt cgcggtatac tcgattagtc
      781 cggtagcatc cgttgcggta aaattacgta aaatcaatcg atccgtttca atggtttgca
      841 tagatgattc ctccaatgat gatggaaata gatcatggtt atctattccg tattccgtat
      901 tttgttgtgt gtgtgattgc atagtacata ttcaaatctt ccgtaacgct tatccctttt
      961 tcggtgccaa atctctcggc ttaactagag caggtgcagc ttttgtttta aacgtcgtgt
     1021 tgacttcctt tgtctcgttt atctccttga tctcactgac ctcggtagtc tcattagtct
     1081 gatttgtttt atccgctttg gagaacagat ttattaattt gtccttgtag atgtatccga
     1141 atataaatcc aacgacagcg atgaccgata tgatgatggc gatggtgtat tgttgcatat
     1201 gaagattgga acccaccgcg gctgaagcga taatccaggg caaccgtcca actagcagaa
     1261 tagtgaagaa gcgtaaagag ctgatggatg tcagcgcagc gacaaataca agcatatctt
     1321 tgggcaaccc gggtatgagg aaaaagataa acaaaaaggc agtaagtttt cgctcatcat
     1381 gcatgaatga catccatttc atattttgct tctggagcag gcgagataca aaatcacggc
     1441 cgatgaaacg ggtgaagtag aaggcaatcg ctgaacctaa gaccagacca acggttgtat
     1501 agaaagaccc caatgcagaa ccatagatgt atcctccggc aatctgcaca atttctcctg
     1561 gaatcggcgc aacaacgatc tgcaaaatct ggaataaaat aaacatgatc gggccccagt
     1621 gtcccgtgga atgaatataa gctctgaaat tgtccatcga cgacatgatt ctaatgatag
     1681 ctggagcata atagatcagt agacccgtag acaaggcagc gagcagaccc agcagtattt
     1741 tcatcacagt acgttttgag aatttcggca taacgtaaga cccctttgta taatgagatt
     1801 cactattaac agtataaaac gaaatcatga agagatacct acttaacttc ttaagaattc
     1861 ttaaggcgat gctgatccgc tggctctgtt aaaacgcgcg gactatactg gaaggaacgg
     1921 agggatttcg aatgaacaac aacaagcaga ttttaattgc agatgacaat agtgagattc
     1981 gtgagatcgt gaagattttg ttagaaagtg aaaactacga agtcattgaa gccgtcgacg
     2041 gtcaagatgc gatagataaa gtaacgcagg aaacagatct tattattctg gatatgatga
     2101 tgcccaataa gtcgggactg aaggcatgtc tggagattcg tgaaaaaacg agtgcaccga
     2161 tcctgttcct tacagcgaaa acacaggatt cagataaaca actggctttt tcgtccggaa
     2221 gcgatgactt tttgtccaag cctttctcgt ataccgaact ggtggcaagg gtcaaggcgc
     2281 tgcttcgcag atattatgta taccggggca aggaaaaagt cgaggaggcc gagcacattg
     2341 cggtgaagga tctgaccatt cacaaggatg ccaaatcggt gtatatcggt gagaaagaaa
     2401 tctcgctgac ggaaatagag tatcaaattc tgttgctctt ggcttccaaa cgaagaaagg
     2461 ttttttcagc cgaaaatatc tatgaaagcg tgtggcagca gccttatttt tatacttgta
     2521 ataacacggt aatggttcat attcgcaatt tgagaaataa gctggaagac gacccgcagc
     2581 atcctaaata tgtgcagacc gtttggggga aggggtacaa aattgaataa actgctcatc
     2641 gggaaaaaac taaagctcaa gctggtgctt gcaattattc tgtctctgtt tgttgcggta
     2701 ggaacattta tcgtgttaca ggtggttggc gagaccgcgc ttgatagtta tcttagtaaa
     2761 tcaacgttta gcgaaaacag acagcaggat gcgctcgaac gattccagac catggtaagc
     2821 agtgagcact tgtccacaca ggatcatcag cggctctcgg aatggattcg tggggagcgg
     2881 tatctggagc tgtttatgtt tgaacaggat aaattgatat attcgtccaa catacaagcg
     2941 gattctgcga ttaatgaaga actgttaact cagttcttgc cttctcgcac accgattaca
     3001 acggtgcagt ttacagataa aacagtgcag atctatctgg ttggtttcta tgaatatcaa
     3061 tactataacc tgcttttgat tttgacggta ttcgcagcct tgattgcgtt tattgttgcg
     3121 ttcttgctca tgatcaatcg gaaaatatcc tatattggta atctggagcg tgagattaaa
     3181 atactggaag gcggcaatct ggattataag attactgtat ctggtaaaga cgagctgtca
     3241 tcgctcgcaa tgagtattga tgagatgcgg aaatcatttg tggaacggct cggtagcgag
     3301 gaaagggtga gaagcgcgaa tcgagagttg attacggcca tttctcatga tttgcgcaca
     3361 ccgctcacga ttctgctggg atacatggac attattgaac tgggcaaata caagacacag
     3421 gaagacctgc accagtatat tcacaatagc cgagagaagg cgtatcagat caagatccta
     3481 tcagataagc tgttcgagta cttcacggtg tctactgcat cagaggaagg ggacgtagaa
     3541 ttcgaaatct atgatggaag ggagttgttt gatcagctcc tggatgagca gctagcctta
     3601 atggaaaatt tcgatgttga gatgaagcag caatacggag aacgggcctt tttgatcgag
     3661 ttgaaccttg tagcgatccg tcgtgtgttt gataatattt tttcgaatat aaagaaatac
     3721 gcacacacgt cttatccagt gcatatcgag ctgttctttc atcagcaaac cttaatcatg
     3781 acggctcgga accggattaa acctgtcgac aaaacgaagg acagtaacga gatcggactc
     3841 gttagttgcc agaaaatcat cgaacagcat aacggaacat tgaagatatc tcaggcagca
     3901 gacacattta tcttacagat cgaattgcct gttattctca gtaaagaaga tcagaagtag
     3961 cagcttatac aggcaaatgg ggagtatagg cagtttaggc agaaagaatg catgttcact
     4021 tattcgatga aacttccagg tgtcaggaag ggttatataa gagagctata gaaaaggtca
     4081 catagaagag tggcgaaaag aaaaagtgta agtggaaatg aaagtacaag tgacaacatg
     4141 aggggagaga gtttcgtgaa gaacaatcat actccactga gtaaaaatcg ggttttggaa
     4201 gaactggact cgctgggtta ttcgaaccga atgaaagaga ttgcgcggct gggacggaat
     4261 catctggctg tggccccgaa agaatacgca gcgctgctca ttcagctact ggacagcggg
     4321 acagcgtacg aggcacatct ggcactaacc ggagctggtg cggtaaaaga tgcacaagct
     4381 gttatacacg cattaaatca ttctaaggcc ggggttaggg gacgagcagc ctggatgttg
     4441 gcagaggtgg tcattgatcc ggggtataac attgaatccg agattgtttc gatgtcgcac
     4501 cattgccgtc agcaactact gcgaagtatt gtgaagtatg ccagacagga ttgggcagaa
     4561 cgtctgttgc cgatcgtatt ggaacgttgg ggtgccgatg aggctgtttt cctactatcc
     4621 atgtgcggtg aagcaacggt tcgcacacga ctgccacagc ttggatatgc gattgataat
     4681 tggcgggtaa ttacgacccg gtatcctgat ttggtcgctg cttacttaga aaatgcctta
     4741 aatcaggcat cggagagcga caggcccagt gtgtggtatg agatgagcac ggcggtagag
     4801 aagctgagta tagtaagacc agcagtagtc ctggaatatg cattgtctta tggtccaaaa
     4861 gaacagattc atcctgtaat taagaatcag ctgggtatcc tgattcggac tagccctgag
     4921 caagtatttg agctgctcac gaggcaggaa acaagggcat acctgctgaa caacggagtt
     4981 ccggcgggtg tgttgaaaaa gagaagatac ttcaccaccg cgcattggac tgcaatggtg
     5041 accatgcttg ccgaagcacc ttttcaagtg gccaaggtgc tggatacgct tgccccttcg
     5101 agccgtgaag cgttatttaa tgcggcgtat ccggagcagg agcgaacgaa tcgagtgttc
     5161 cctatgacct tgctcgatgt actgccgcat cagttgcgcg acaaggaagc ggttcgcatg
     5221 cttaacctgc gagaagtcaa ggaagaccgg ggaagaacgt tcgatatgac agcacgtcgc
     5281 ctgattatac aagttagaga aacgctggaa cagtctgttc aggtatcgaa tgcggatgag
     5341 cgtgctacgg cgtattcccg gttgatacaa agcacggctt tgtcccgtag tgggatggag
     5401 gaaacaatac gctttctgac aagggtaaaa aacgatcagg acccggtacg tttcatcgtc
     5461 atggctgaac tatcgagatg tccagtcacg atgtttaagg aagagcatgt gccacatctg
     5521 acgatcctgg tcgacagtgt cattgaggcg agagatactt cacatggaac cagaaccgca
     5581 gtcgagcaat tggcttttac cgttctgcgg gagcatgcaa atgaaccgga gcgtcccttg
     5641 ttccaattcg cacttagaac actcaagcgt atggcgatgc gtgatgggca gtttatgtta
     5701 ttttccagag agtgggagag tctgccgcag gccgcgctag aaaccttatt tgaggagatc
     5761 tatgccatgg gtatagaagc gaataaacgg gagagtgact acgtcgttct acagatggct
     5821 agtgcatttg gcaaagcaat tgatcgattg cccaaactcc atgatctgct cgaggaattg
     5881 gtgaagggta aaaaatcagc ggctcaagcc gtcaggtact ggctggcacc ctacaagacc
     5941 agggataaac gggttaggga actgctggac cttgatccga cattcatctc attctacgaa
     6001 gtgttcgagc acttgcacct gaaacgtcag gagtggcttg atccgtttat ctccggcaaa
     6061 gtcctcaaag gcaagcattt aacagggaaa acgatctatc tcgttccggc ttataatggc
     6121 ttttaccgct ggttgcctcg tcagcaacag gcgctggctt cgctgcttga ccgggtggca
     6181 caagacaaca agcgaagctt ctatgagcgt gcaaatgcga tgcggagttt ggcgggcatg
     6241 ccggattatc gctcgaatca gccgttagag aagctgttaa ctgatccaga agtacatatt
     6301 gtcgaggctg cactgcatgc cttttcgcta acggaggaac cggaagaggc tcttccggtg
     6361 ttattaaata atctggatgg agatcgtgca cgagtggcga tgtattctat tccgcggtgt
     6421 gcacgcaggg tgaatccggt gctgctcacg tccatgcttt cggacctgtt agaccgggag
     6481 aaactcaaga ttacagtgcg gaaagaagca gtgcgactgc tgggagccta taaaatccgc
     6541 gagagtgtga ccttactcgt ccgggaattc gaaaagccaa acaggcacaa ggatgtcatc
     6601 attgccattg gtcatgcggc cagacaatgt ctggatgatg agcgaagctg ggcaatgatg
     6661 agtgttatgg cgtcttcttc ggatcgagac attgcacgca gtttgctgaa tcagcgtccc
     6721 gatgaacttc cggtggaagc gcggcagcga tatttacaat ggattacgga gattgcaggt
     6781 catgatgacc cgattgtatc gatggaagct tttcatgcca tgtcacgttg gggaaaggta
     6841 agtgcagagg ttattgcaga ttgtgctggc acagcgctga gcaatctcca ggagggtaca
     6901 cgctggaaat ctgcactcca tgccttcgtc acggtttgca aagacgggaa ggtgaatgat
     6961 cgggtcatgc aggtcactcg ggaattggca caagcaaagg tggaggacga ctggaacgca
     7021 ggcagtgagc gggatttgcc gcatcgtcag cgactgcacc agttgattga ctcgcttgtc
     7081 tcgttatctc cactggtgaa aaggaaactt gctccgttat atgcagccat gatcgagact
     7141 cttcagcaac atgaaatgct gaaactcacc gtgattcgtc tgcacttggc tgcgatggac
     7201 tggagccagc cggatcaagt gatcacccgg ttgtatcctg tcattgacgt tgcaaatgcg
     7261 aatccggttg tactgaactc ggtggatcgg caggttacac gtacagtgct cgatagcaaa
     7321 gggtattgga atcctgaaca tctgcttcac atcgtagatg tgttgagagc gcgggcggat
     7381 ataacttctt catggattgg actctctttg ctcaagattg ctggagagga actattatgg
     7441 aaccaggatt gccgcgaacg cctgagagca taccggcaac atgagcaaga agcggttcgt
     7501 ctgctggcgt tggatagttg gacaatactt gaataacatc acaggaaaag cggtacagag
     7561 attattctgt accgcttttt tggcatgatt taatgttcag aagaacatgg ttcagtgaag
     7621 gtttagcggc ccgcattaat ggattcaaac atctgctctt catatttcag tacactgtcg
     7681 cttccgggct tggttactcc ggtgtataca tttttggtat tgtgatagaa ggcttcagcc
     7741 aaatccctga gacggtcaag atcatgatgc ttcagggcaa tagcctggaa tataccgctt
     7801 aacatatatt tgtcgtctga actatcgtca agatatctca aattaagaaa ctcattgaga
     7861 acatatactt tgaattcctc aagctcttca gtagtgggga catattcctt agcgagcttc
     7921 tctactgcag cagccttttc cttcggggat tgctggttgt ttgcgatttg atcaatctgt
     7981 tcttcccaag cagaggaagg gggttcatcc tgaatagaga cagcaggtga cacatcacta
     8041 ccggctccac tgtagaacat caatgtcgta aaagtgtaca tcaggaatga taacataaac
     8101 gcaatctctt tcattttttt cctccattgt atatttatat agagtagtgt accagagatt
     8161 cgaaagacat gtcatgtaat gtagatttaa ttaaacatgc aaataagttc tagatgtcaa
     8221 aataataaat ttactttaaa gcggagaagt gttagtatgt ggtggaaaat gttagaaaaa
     8281 ggatctgaat tatgcttcta catgatctgc actcaaggag gcatcccgta ttgaacattg
     8341 tatttgtcgt ggatattgtg ctcagtggcc gaggtggtat ggagacagcc ctttcgttaa
     8401 tctatcatga gctcaaacag aaacatgata tcaccgtgat tttaagaggg gagtctgcag
     8461 atgatgcctg ggaagagggg ataaatacga tcactttgtc tgccaagatc aatgatttta
     8521 tcccaaagca tattttgttc aatatgtatt ctgctgcctt ggcgaacgtc atgaaagacc
     8581 ttccgagagc agatatcatc gtctcgacag gtgctattgg cgtgaaagct tcaacgatgg
     8641 cagtgaagcg gttagatatt caagtaccgg tggttagctg gcttcatttt aatctggatt
     8701 tttactatca attcttcgaa gatttacgtg ccgcggatgg ccatctggcg atcagcgaag
     8761 ggaatttaag agatttaaac tgtgtttttc ccgaaaaaca aaacaagctg gtctataatc
     8821 ccgtgaaatt tgataacatt ccatatgtga acagagcacc tcatcccgta tttctggttg
     8881 ttggaagact ggccaaggtg aaaaatgtgg atcagatctt gagggctttt tctcctttgc
     8941 aaaaagaata ctttgaatta cacatcattg gtgatggtaa tcaatatgaa tctttagtag
     9001 aactgtccag gcaactggga ctgcagaatc acgtggtctg gtatgggtgg caaccaaggc
     9061 catgggatac ggtgattagt gcgacttcac tagtcctggc atcggataca gaaccgtttg
     9121 ggctggttct gattgaagcc cttgctagag gcattccggt gatctccagc aactgcaagt
     9181 atgggccagg agagattata aatgacagca atggctggct gtatgagcct gataatctga
     9241 agcaactgac gtctattttg gatggcgtta tgcaaggacg cttgccgctt cctgcaccag
     9301 aattatgcag agagtcggtg agaagttacg ccgtgcaaag catcgctgaa cgttttgaac
     9361 aggcgctcca ggacattgaa aatgaccaag ctattcaaca gaaatgaatt gttcacagaa
     9421 tattcaaaaa atagttgaca cagcaaaaga atggaagtat tctagaaaaa aattcaatta
     9481 aatgaaataa aatacattgt actccaagaa gaattacaca tgttcatacc atgcacatgg
     9541 actctacagc atatccaatt acaaaatcta atgtgaatta atttgatgtt cacgttaact
     9601 tcctagaatg acctctcgat ctccttcctt tcttttttaa ctagacttga aagtgcaatc
     9661 tttgtgctag acaagccttt accccattcg ttcaacgttt gaatcgttca gcttttttgt
     9721 tttctcttac agcttcctct ttcaataaac cttttttgct caaaatgcaa gcgcttacct
     9781 tacgttgtta tatgagagga ggtgagaaga catgacgaat tataaaaaac cgacttttcg
     9841 caaattggaa tccgcagcga ttgctgttgc agcaggttgt ggctgtggtt gcgcattttc
     9901 agtgggcgcc ggttatggat cttgctaatc atttattgtt catgaacaca caaagaggcc
     9961 tgtttatcgg cctcttatct tgattattgg aggcatgttc atgcaaatgg aggaacgatt
    10021 gcatattccg gatgtcgcgg tgtactacga ggatggtcag tatgtcgtac ataacgttca
    10081 actcaactgt tgggttgtgt actcaccaag cgagtatgag attgcatcgg aattgatata
    10141 tgacggaaaa tcggcaactg aattgattga ttcaggctta aacccgcagc aggtgaagca
    10201 ggttgcacga aaaatgttga tgtatcgtgt agcctatcaa ggagaaagac ccgctgagta
    10261 ccacatgctg gatgtgatgc agaagcaggg aatggggaag gttccgcctg ctgctgtata
    10321 tttcgtaacg acctataaat gtaatctgag ctgtatttat tgttatgcgg acagcagccc
    10381 ggagcgctcg atgaatgggg atatgaatac ggaagaagcc aaagacatga tcagacagat
    10441 caaggaactt ggcagtagta ccatcgtgtt tacgggtggt gaggcgttta tccgtaagga
    10501 catcatggag ctcatggcct acagtaaaga aatcggatta cgagttaacg taatcagcaa
    10561 tggaacatta attaacagtc gtgaaaaggt caatgaaatt gccaagctgg tggatgtgtt
    10621 tacgatcagc tttgactcac tcgacaaaga ggagcatgaa gccaatcgcg gtataaatac
    10681 gtgggaacgt gctcgtaaat cgattgatct tatcttagaa gccggaatta aattgaaaat
    10741 caaccaaacg gtgaccaagc ataatcggga ttcagttgag cccatgctgc agtttgccac
    10801 ggagcgctcg gtacgcttga atattgtacc gctagcgacg cttggccgcg gggatgaccg
    10861 catgcaggga ctgaactttg gcgaacgtcg ccgaattgcg gatcggatgc tggatattga
    10921 gatgggagac gctcatgaag attgtcatgc cttgaacgta aggcaatatg agcgtagacg
    10981 gcattgcggt cacggtacga gcgagttttc aattgatgcg aagggcaacg ttttcccctg
    11041 caagctgatg cattctccga tgttccacgc tggatcgatt cgagagaagt cacttcggga
    11101 aatatgggag acgtcggagg tgtttgaacg ctcgcggaac aggacggtgc acacgttgcc
    11161 agagtgcatg aaatgtacgt tcagggaatc ttgcggtggg ggctgtcgtg catttcattg
    11221 gggagctaca ggtgacattg acggaaccac ccctcatgat tgttcaggga tccggcgtgg
    11281 aattcgtaga aaaatggtag cttatttcaa aatggcagga ggtaaaccga atgagccagt
    11341 ggtttcaaat agccgatgat gttttttttg atgaaaatgt agaaggaata ttcattcttt
    11401 cggatgctgg tgaggtattt gtattggagg atgatgtcag taaagcggtg tggaatatgc
    11461 tcgcagattc tgcacaatct cttgatgaga tgtgtcagca gatcaagctg aaattcaata
    11521 ttggcgatga agatcatgtc gaggacgacg ttcgggattt tgtaacggca ttatccaaaa
    11581 taggagttct gaacgaatgc ttagtacccg cagacaggat ttcctgattc gtgcattgca
    11641 acaaggcaag tccatcccca tcgtgattga gggtcactgt atgcaccctc ttcttgttga
    11701 agggcagcac attactgtgc atcctttact ggaagacatc aaagtaggcg atattgtgct
    11761 ggttcgtgac cagatgaaag gttttttggc tcatcgcatt atcagccttg gacatgactt
    11821 cgttgttact tcaggtgacc gcaatcacat gtctgatcct ccggtacggc ggaacgatat
    11881 tttgggacgg ctggatgtac cggaaaatcc aatgctcaat cagaacccgg agcaaaatcc
    11941 tgatcagcgt tcatcgacct taactgattt acaagggtta tcatgtgaaa taaagattgt
    12001 tgttcatcct gatgccattg atagttcata tggtgaagtg ttgtctcgtg cctttggtat
    12061 agatgtcgac attgcggaaa atccgctcac ccagctaaag catatgcggg agaagggatg
    12121 gacatccgtt gtcattcatg aaggtgcaag acagcatcta tctcagttgc cgcatgttgc
    12181 tagcagggtt gtgatctttg ccggttacga ggtggcgagg gacacggatg aatctgccgg
    12241 tattattggc atgagtgatg tggacttcgt agctcgaaca gcagtcgagt attggaataa
    12301 cctgcatgca gaactaagca ttgcagcgat tataggtttt catatgaggg ggacaaccgt
    12361 atgtcatggg taattaccgc cacatgcgaa ggagaacttt tggctaaatg tatcgtggct
    12421 tgccccgaag aagccattca gacatctccg gatgcgaagc aatattatat taatccatcg
    12481 gtatgtaccg attgcggcct gtgtgatctg gcttgccctg tggcagctat ttttccggaa
    12541 agcgctgtgc cgaagcaatg gagaagcagc attgaagaga atcgtttgtt ctttctcacg
    12601 tagtcacgcc atcataacct gcatatgtca gcgcaaggcg gaagaggctt gcgttgacat
    12661 gtagtatcag ggaagaaggg gagccgtaat acgatgccga cacttcgtgt acgagttggg
    12721 caatatccac tgttattgga gttgtgtaga gccattaatg agttaagaca agataagttg
    12781 tggactgttc ctaaggaacg aaactatccg cctgcgctct tgaatcttat ccgtaatcgg
    12841 ggtcttcgtt ctaatgtcta tcgctattgg ggcagtttgc ttctgaaaga tatgttggct
    12901 gtccaaagtg agccggaagt taaattggtc aaacgcatat taagtgcatc tgcggatacc
    12961 aaagcggatg aggttatggc tgaatatgaa agtcatctgg cttcacaatg cgaggcgatt
    13021 cgtgagtatc tcgcaccttt aatccaaaat tttgacattg ccgaggttgt tgaactgaag
    13081 ctttacccgc tatcaaccat gcctcctccg cagatcggaa gattcggggc cagcctgagc
    13141 aaagcaacaa caacatccgt tcatttggcc ttcggcgcac caccgcttca tctgtgggat
    13201 gactttaacc tgaccgtctc tttcttcgca cgaggcggca ttcattatct cgttaaagaa
    13261 tggctgcttg ctcacgaagg tgaatatgga gaagtaaagg aaggtttgaa gccgtatctg
    13321 attaatctgg tatcggcgat cattttaatg gaagtggatc actttttcag cacgaatttt
    13381 gatctggttt tccatgaaga ggacaaatta gtctatcagt gggcactctc gcaatatgat
    13441 ggcaagatgg ggtttggtaa ccatctgatt caatatgttc gcaatctgaa tgcggactgg
    13501 ccgcctccgc atctgggaga tgttcgtcat gacgtcccta tgacggtcgt acatacgatc
    13561 cagaagaagg ttcgagtctc cataagcgac cagtacaacc ttttggcaaa caccagatgg
    13621 attgctgatt attatgatat tgcggaggcg gaggatgatg gcggattggg gagggcatat
    13681 ccgtttctgg tcttgccatg gaatgcagaa ggtgctgccg agatctgctc aaggcatcat
    13741 atacagcaca gctatcatga agccgccgtg acttatgagc atatgacggg tcaaaagcag
    13801 ttcgatacca ccgataccct ctgtctgctc atagacgatg atgcggagtc ctcttggaag
    13861 tttgttttac tgtgtccttc cgcgcgtact ggatcaggtt attacattga gacttccgta
    13921 ttgtcacaga ttcatacagc aatcgctttc gtagattctg cctcgggaag gagaatatta
    13981 tgagccgttt acaggccgga ttggtccaga tgtggatgat tgtccgggca ggggatcggg
    14041 cgatctgggt attgttagcg cttattcttg cactcggcgt atggcctggt ttcatggtat
    14101 gggcaatcaa gcattcggtg aatcaactgg ctaatggcga ccgcaacgcc tctttagctt
    14161 acataggcat tattgctggg gctggcacga ttgcgatttt gctcaacgtg atacagccct
    14221 attttcttag aaaagtaaaa gaccacgtct atcataatct gtctatccgt ttgtttgaca
    14281 atgtgaatcg cagaacagaa aatgagctgc tccgtgcgtc gacccgaaac cggatttcaa
    14341 gcacctcgga atcggtcagc tccatctacc atggtggact ggacgggctg tcggcactac
    14401 tccaggtcat tataacggga ttttccctga catggattct gctagttgta gcatggtggg
    14461 cgcccctgct aattctcgct ggaacggtgc ttaatgtttg gctcatgaaa aaggcagcag
    14521 ctactgaatc ggattttcta caaagcatct cggaaaaaac gaggctggaa ggaacttttc
    14581 tggacatgct gaccacatta aagtctgcca aagaaatgcg tgtttttggc atatccggtt
    14641 gggtgaaaga caaatggcag accgagcaga ttcgaattgc acagttaacg atcagacaaa
    14701 tgatcaagac cggattttac agattggcag gtcaacttgg cagcggggtt gtaacaacca
    14761 ttgtattgct ggccgggtta tggaagcttt ggcaaggtac actgcatccc ggagaagtcg
    14821 cagcactgct aattgggggg ctgcatctgg aacagttact gggtctggtt cttagccagg
    14881 gcaagcactg gttgggacgg aaaatgttct tggcggaact gattcagcag cccgcagagg
    14941 aacagtcgaa aacagtggca aatccggtta cagagacagt tgcaaacaca gctgttgcca
    15001 aaagtacaaa cataactccg tatgcgggta tggatacagg cacagtaggc tgccaaaata
    15061 atgatatcca ttctacctgc gccatttctg ttcgacaact aacgttcagt tatgacgggg
    15121 atcatgatgt gctgaaaaac atcaactttg atattgaacg cggagccagg gtggcgatcg
    15181 ttggcgccaa cggctcaggc aaaagtacct tgatgctgat gcttgcgggc ttgttgaagc
    15241 cggaccatgg tttcgtagtg tcggaggata caggtggctt ctgtttgcaa gactacggac
    15301 gttataaact atccgctgcc gagaacgtgt atctgggcga tattactcgc aaggagcata
    15361 cggaagacat aatggaagca ttgaagctga ccaatgccca atttgtaaac acactgcctc
    15421 aagggctaca aaccgagttg tggccggaag tcgggggatc ggatttgtca gaaggccagt
    15481 ggcagcggct cgcgttagcc agaagtatgt tccgggctat ttatcgggca ggctcggtca
    15541 ttatcatgga tgagccaacg tccaaactgg acccgagtaa cgaattaagc attctggagt
    15601 ccatcattaa ccgattagag ggatacaccg tattgtttgt tgttcatcgt ctggtgggtt
    15661 gtgcctttgc ggatacagtt cttctgatgg atcagggaga aatccgggac tatggaacac
    15721 atgatggatt gcttcagaca agcgaacctt atcaagcgat gtggaaagcc tcttcttctt
    15781 ttatggagac gatgaaggaa gaggaaggag gggacgtggc ctaatgtggt taaccaaggt
    15841 aaagaacaaa cgaaagttgt taccatggat tgcgttcgct ctgtccgtga cactgttcaa
    15901 agggatattg cccgccgttc gcattttttt attcggttat gctgttcagc aagtgatttc
    15961 cggggtggat ctcgatcgga tgattctgct gatggcctgg tttgcggcag caaccatcgg
    16021 agagaaagtg atggattcgt tgtacggcat tgcgctggag ggactgcgtg ttcatatggg
    16081 ccgagccgcc aaagagctgt atatcgatca atataacaaa gtaccctatc agaaacttct
    16141 cgatgcctcg ttttccgaat cagcggagaa ggcagcgaac ggtctcgatc gtggacatcg
    16201 cgttcttacg ctggccctgg atgttctgag tgccgcagta actttaatca gcttgggtac
    16261 agcgctatgg tttgtcacga aaatcgggtg tctggtgatg atggtaacct ttgcttttgt
    16321 tgtaatcaaa caatacaagc tgggccgtca gatgtttaac atagaaaatc agctgtcagg
    16381 tcagcgtatc cgtgaaaatt attaccgtag cactgtcatg gactttcaac tgggcaagga
    16441 acgaaagctg tttggatact ccccttatat cgtgggtctg tggaaaaata catttacgga
    16501 catcagcaag accaatcaat cctttctcct tacctcccaa aagacatcag gactgatgca
    16561 gattggtcaa cttcttctca tctcagtggc ttatatggta tcgattctga cggccagttc
    16621 atccatcggt ggtttaatca tcgcctttca attaattgat gaattgcttg gcaaagccaa
    16681 tgcatttgta ctggagctgc gcatgtttac cagtgaatta ctcactgcgt ccaatctctc
    16741 tcgttttttg gctaaagata ctgctgatca agtcgagacc cctgccaagg aagcgaacaa
    16801 cgaaattgaa ctgaatggag tgggattctc ctatccgaat cacagcaatc ctgtattgac
    16861 cgatgtgacc atgcattttc gtactggaga gctcgtcggg ctggttgggg agaacggagc
    16921 tggtaaaaca acgctatgca atctgatctg tggtttgctt gagcctgccg aaggcgagat
    16981 ttgggtggat ggaaagccta gcttgcacac cgacaggttg cgttcagtct ccgttgctta
    17041 tgctgatttt tccagattcc cgctaagtgt tcagcagaat gttggacttc atcaaaagtg
    17101 gagtgatgtt gcgcagcagc ttgtacagga catcatcgag cgaagcggag acaagcggct
    17161 cggtgcaggg tatacagacg gaacggagct gtcgggcgga caatggcaac gtgtggcggt
    17221 tgcccgggca atggctaata cccgaacgat gctgatcctg gatgagccta cggctgcgat
    17281 ggaccctgtg atggaggaaa gtgtcgttcg aagtgtgaaa caatttgccg ctcaaggcaa
    17341 agcggcattg ctgattgcac atcgggtcag tacggtgatg cattgtgaca gagtttatgt
    17401 aatggcggat ggacagattg tgcaggaagg cgcaccgctt agactgttgg aggaagatgg
    17461 cgtattcagg gatatgtacg gtgcgcaggt tgcattgctg aggaagcagg gaatggccgc
    17521 atccgtcgga tgatatctgg aagcgttgga aaggggaaat atcgatgaaa gtactcgtcg
    17581 tatcacgtgg aaacggattt ggacatgcga agcgtgattt gcttgttgcg cagcggctta
    17641 tacagttcaa tcatgaagtc attatcgcgt cttactcctc cggatttcaa tacttgcaga
    17701 gggtatattc aggtcaattg atcgatctgg agctgccttc tgctggcagc agtgccgagc
    17761 gaaccttgaa gttgctggac ttgatacgtc gcacacaacc cgatgggatc gtggtggatg
    17821 aagagctgct tgttctacca cttgccaaaa gtttgggtat tcccacctgc ttcattacca
    17881 attggttaga ggatgaacag gagacgctgg gttatctgca catggcggat cgaattgcga
    17941 ttgtggatca gctggaacac tggatgttcc cgacatcgga ctcgattcgg gagaagctgc
    18001 attttgtggg cccggtggtt gaagtgcctg aacgggctgc ggccagggag aaaaagattg
    18061 tcatcacgtc aggctcagcg acgattgtgg acgttccttt tttcaaaaaa gcaatagcgg
    18121 atctgaaagg ggaaaccgat tatatcaagc tggtgtacag cggtacattg acgaaatcat
    18181 tgcagcggct gggggatgaa acgacacagt ttatcgcaga cccaagctct ttcatggata
    18241 aagtgagaga cagctcgctg gtggtgtgca ggggtggaca tacgacattg tgggaattgg
    18301 cttcgctggg tatacccgcc atcgctgttc cccggcggga agaagtgaat cgcagcaaca
    18361 ttgtatatgc acggcagatg ggcgagagag gttatatccg ttggctggag gaatccgaca
    18421 tggatcaggg tttgatcgct gcgtatgccc gtgagatttt gcgaggcgag acacagcttc
    18481 aaacgtatgc ttatgatggt gcagcactcg atcatctgac ctcttgtatt ctggaaagct
    18541 tttcacttca gcttgcggag aagccgttat gaacgtgaca gtcatcatcc cggtttatgg
    18601 caaaccggat gtgttgcacc tgactctgca ggcgcttgcc gggcagcatt actccgactt
    18661 ttccgtctgg ctggtggatc agggaggcac gattcctttt gagcagttca ggaatgccta
    18721 tgaggacaag ttgcgtattc attacatcga tacccctgcg catacaacag tgtctgacaa
    18781 acggaatagg gcgattcgtg aatccgctga ggatgttgtt atttttctgg atgcagatac
    18841 gattgtgtgc gctgactttg taggtgaaca tatggcgctg cagtgtgccg ggaacgaggt
    18901 ggtgatcggt tatatctatg ggaagaaggg catgcaacgg gaagagctga actatgaggg
    18961 gaagctggag tttgaggctt ttatgcgatg gtttgagcat gaatccaggc atattccaga
    19021 cgagcgtgag aaatattatg agccggtgca ggatcaattg atgcgattgc agtggccttg
    19081 ggctgtattc tggtcaggta acatctctgt atcccgagct gcattacagc gtgctggcgg
    19141 atttgatcac aggttcaaag gctggggcat cgaggacatc gaggttggct acagacttgt
    19201 tcaatctggc tatgaactca ccttaagccg ctcggcttgg gctgtgcatg tgccacacga
    19261 ggtggatgag gcgaagcgaa tgcaggatca gacggcaaat gccagaatgt ttttacgaaa
    19321 atatcctgca atggagattg aattatattt tctcaaagtg catgactgga ggaaggtccc
    19381 agatcgaggc gaagccatag ctaaagcagc aaataaagcc acagtaacag caacgacgtc
    19441 catagccgac accctcatgc aggaagatga actgacccat gggatgcaga agattataca
    19501 gatggtcact tccagctacg acacgcactt tttactggta ggttatgatg ccaaactgtt
    19561 tgttttatcg caggtgagca cactgattga ccccagagcg atgagcgaag ggctgatgaa
    19621 tgtttctgga aaaaaggtct acaggcttgc cgggagctgc atgccgtttg aggcattatc
    19681 atttgatgtt tgtatcatta cacctgtgtg gacgatgtac aaccccgaga tgattcctca
    19741 tctcctcatg gaagcattga gaacctcacg tgtatgctat tgtttaagtc caagaacgga
    19801 aattttgcct ctgcttgcag tcctcacttc tttgaaaaag ctgggcagag acatcgaata
    19861 cagcattgtg gatgtcgtag atcaaaacat gaagcttatc acgtgcaaag atcgtggaat
    19921 gattcaagtt caggaagggg gcatgttaga tgatcaaggg cgttaccgtc atcattccta
    19981 catataatca ctcggattta ctggaacgaa cgcttgtatg tctgaaacat caggaggctg
    20041 acatatcatt attcgaggtc atcgtgtgtg atgacgggtc aagtgatgat acgaaagagg
    20101 tcgcctgttc ctttgaatcc gatctagatc tgaggtactg ctatcagaag gatctggggt
    20161 ttagggcagg aacggcacgt aatatgggac tgcatctggc taaacatgag atatgtgtat
    20221 acctggatac cggtgtattg attggtgccg accttattct taacgtcatt caatttcacg
    20281 atcttcacga acatacaatt ggactcggca cggttcatgg tatgaatcaa aaggatcacc
    20341 agcatccact tgctaaatac ttgcaatcta ttgcttcctc cgaacatccc gaggcatgct
    20401 tgcggaatcc catgttgaag gcttatcccg attccagaca aacacagttt gatttttatg
    20461 aaaatgatct ggatcgaagt tctgctccat ggtcgatgtt ttggacaagc atggtttctg
    20521 tggaaacctt tctgctaaga caggtgggcg gatttgatga gtcgttccac ggctgggggc
    20581 acgaggatct ggaattaggt taccgcctct ggaaggcagg tttgcatttc cggtccgatc
    20641 cttcgctccg cgcgctgcat ttgccacatg agcagttcaa tccggtgcag atgacaagtc
    20701 ggaagaatca tctgcacttt gtgaagctgc atcaggaact tccggtggaa ctgtcctatg
    20761 tgaacgaaaa ctttattttt gaaatgctgc ttggacagtt gaatgttgcg gatcaatacc
    20821 tgcctcaaaa ttatgatgat cttgatccga acctgcttgg ttcccatgaa gaaggaagac
    20881 gattggcagt ggggtatata accccggcgt ttgctagcag gttgaacatt acggatgtgt
    20941 ttgcgtgtaa tcaacgtaac gccgagatta ttcgtacaca gagaccggat gttcacaccg
    21001 ctttcaaagc agggtttgtc aatttctgtg aggataatat gtatcagacg gttatcatta
    21061 cagatgtatg gaaagtcatc ccgattacat tgttaattgt actgctggat gacatgctac
    21121 ggatagccaa acgagtctat ctgctggata cagcggattt agagctcgat aaactgccga
    21181 tcgtcggcga gcttcttcca accggattcc atgcggagtc gattgcaagt gctggcaaaa
    21241 cagaagttta tgccataacc cggctggtgc agcagcttca tgtcgaagta aacaacctgt
    21301 aaaggggaca ggttgttttt cgtttttatt ttcactacaa tcgagtagaa caagtgcgct
    21361 acaccactat gttaatgaac cgggggagaa tgaggatgac cacgaactcc attgaaaatg
    21421 agaaagaact gtcaccggaa caacgtgatg agttgttcaa ggcattaaag acccgttttg
    21481 aaaagaatac gagtcgtcat cccgatctgg aatgggttaa cgttgaggcc aaactcgaag
    21541 cacacccgga taaactgtgg tcgcttcacg agatggagca aacaggcggc gaaccggatg
    21601 tcgtggagtt tgacagtgag acaggta
//
