LOCUS       NZ_CP023865            22640 bp    DNA     circular CON 27-APR-2024
DEFINITION  Actinoplanes teichomyceticus ATCC 31121 chromosome, complete genome.
ACCESSION   NZ_CP023865
VERSION     NZ_CP023865.1
KEYWORDS    RefSeq.
SOURCE      Actinoplanes teichomyceticus ATCC 31121
  ORGANISM  Actinoplanes teichomyceticus ATCC 31121
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinoplanes.
REFERENCE   1  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Complete genome sequence of Actinoplanes teichomyceticus ATCC 31121,
            type strain of Actinoplanes teichomyceticus and producer of
            teicoplanin, isolated from soil near Nimodi, India
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2017) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.5
            Genome Coverage                   :: 184.1x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003711105.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:18:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,294
            CDSs (total)                      :: 7,220
            Genes (coding)                    :: 7,116
            CDSs (with protein)               :: 7,116
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 27 of 104
            Pseudo Genes (incomplete)         :: 92 of 104
            Pseudo Genes (internal stop)      :: 11 of 104
            Pseudo Genes (multiple problems)  :: 22 of 104
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:55:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5071703
            Orig. end                         :: 5094343
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22640
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="18"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22640
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22640
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12640](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12640
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(115..130)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    complement(352..367)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.91"
                     /tool="antismash"
     misc_feature    complement(353..367)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    447..465
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.07"
                     /tool="antismash"
     gene            complement(454..951)
                     /locus_tag="ACTEI_RS22375"
     CDS             complement(454..951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692366.1"
                     /locus_tag="ACTEI_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_122979440.1"
                     /transl_table=11
                     /translation="MGEPAMPIRRRIELSVAEARLRFQQLVRLTGLTGQITVVVDGGRP
                     IAAIVPARDVLQPAPPVAPVSPPVPVAPAVPAAPPGPPVPAAQAVPAAAEGRPGPESSA
                     GWLRRIEKVREDVRRQHAGRIRELSQSLDEAWRLLDEIRPPGTDRHVDTLRAAHGDLRR
                     IQ"
     misc_feature    973..988
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 20.08"
                     /tool="antismash"
     misc_feature    complement(975..988)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.5"
                     /tool="antismash"
     misc_feature    complement(976..991)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.51"
                     /tool="antismash"
     gene            1024..1653
                     /locus_tag="ACTEI_RS22380"
     CDS             1024..1653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692367.1"
                     /locus_tag="ACTEI_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /protein_id="WP_122979441.1"
                     /transl_table=11
                     /translation="MTDSLVDLPTATDVRDVVSRAAQALRTAGDRDWHLRAGDLSWSCW
                     ETVEHVADDLFSYAGQLAAEQPPSDRYVPWGYRRSRPDAPALTVHVDHAEGNAALVQVL
                     EAAGGLLAAVVQVSPPQRRGFHPYGIADASGFAAMGITEVLVHLYDVAATLDLRWSPDP
                     GVCARALRRIFADTPAGDDPWATLLWATGRVGLPGRPRRTEWRWHA"
     gene            complement(1752..2603)
                     /locus_tag="ACTEI_RS22385"
     CDS             complement(1752..2603)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTEI_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_145830887.1"
                     /transl_table=11
                     /translation="MSVVYPSYLAVAGAAAGGSAARTVAALRTVFVLGYLAGLGLFSLA
                     AQGEASVGPAVGPIRVAVGVAVVAALVAHLPRPAPAGEPGPPPGTDPAAAARPAVLAAA
                     AAVLLMRAADSLRLVYLPLYALGAGTPRPMISALFAVTVAVEVAVLAPVSAVGDRIGSR
                     WTLLGVCGIGVLSFLTLIAGGGYPGLVLSQALYAVFAAGFPSIGMVLLGETLRAGLGGG
                     AGAYTALVQVGATAGVLTPLVVPGYTVAVFWIAVLFCLGAAVLLVARPRRAGRGTPVVA
                     GR"
     gene            2602..3063
                     /locus_tag="ACTEI_RS22390"
     CDS             2602..3063
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023134.4"
                     /locus_tag="ACTEI_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_122979443.1"
                     /transl_table=11
                     /translation="MAITRTAAGWIRQPGPSAASTSPLFAYAVRPGPPSRADAHRLLPL
                     DEALRRVNTAAAVAPVTPVLAWAAPDADPVVTDVAAPTAPGTALNAALARAAIGFLAGP
                     HRSNLRACTAPRCVRYFVKEHGRQEFCKASCSNRARAARHYQRHHPTGT"
     gene            complement(3233..3739)
                     /locus_tag="ACTEI_RS22395"
     CDS             complement(3233..3739)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692368.1"
                     /locus_tag="ACTEI_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GAF domain-containing protein"
                     /protein_id="WP_122979444.1"
                     /transl_table=11
                     /translation="MHISLHDRLADPARLRELARYDLAAQELRADLDRVAERSAKLLEA
                     PVSLVTVLGADVQQIVGSYGLGDWVAVAQGAPAEWAVCTRTVLDGEPYRVADFRDDPVH
                     AVNPFLATTGLRSYLGVPLITPDRLMLGAHCVVDSRRRIYTDVDLAVLGDSADEAMTAL
                     LRHRR"
     gene            complement(3757..5346)
                     /locus_tag="ACTEI_RS22400"
     CDS             complement(3757..5346)
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692369.1"
                     /locus_tag="ACTEI_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_122979445.1"
                     /transl_table=11
                     /translation="MKRFWADLGVNFKIMFAIGVASVVALLIGVLGLTALSGASASAQH
                     IYASNLTSVAALGRVQNAITQSRLDLVSHAVYRDGTNKAAYEKNFTADLAEADAALREY
                     QTTGPAGAPATVRSLTAAWGEYVDVARTRMIPLSRANRLAEWQQVRGARVTPLMETVRD
                     SLTELNQAERAAAAHSAAEAEDGYRASRLRSILILVVGLVGALGLGVVVARGIVGALRR
                     VTTVCEALAAGDLTQRTGIAAADEPGRMSRALDAAVLRLRETLATIGGSAVTLAGASEQ
                     LTAISSRLESGAGDVAERATTASSASEQVNTGVQSIAAGAEQMSASITEIASNAAEAAR
                     VAGEGMTVAARTNDQVAELGSASAEIGDVVRLITSIAEQTNLLALNATIEAARAGELGK
                     GFAVVAGEVKELAQQTARATEEITARITAIQDSSTSATAAIGEITDVIQRIGDYTTTIA
                     SAVEEQTATTGEMSRSVAEAAANSGAVARTVTSVAEVAAATAEGARTTQQAAADLTRLA
                     GDLTTLVGGFRH"
     misc_feature    complement(5298..5312)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.74"
                     /tool="antismash"
     gene            complement(5482..7074)
                     /locus_tag="ACTEI_RS22405"
     CDS             complement(5482..7074)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014445646.1"
                     /locus_tag="ACTEI_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_122979446.1"
                     /transl_table=11
                     /translation="MSAVTATGVPTPAHAPPAGRRGNPWLSLAAVAFGLFMVGLDGSVV
                     SIANPEIGRDLRASTAQLQWVTNAYLLALAAALILGGKLGDRFGRRRYYLIGVAGFTVS
                     SVAIGLAGSIDGVIAFRAAQGFFGALLMPNTLGILRAVFPPRRFGMAVGIWAMVSSVST
                     ALGPIVGGLLVQHVSWESVFYLNAPVGVLALIVSALVLPESRNSTGRHRFDVAGVALLA
                     AGLLVLVFGVVKGETWGWGSGRTLGTLLAGLLILVFFGWFETRLEHPLLPMRLFRSPAL
                     TIGALITAVNFFTLLGSIFYIMLYLQNVRGYSPVWAGVLTLPLSLASVVASPVGAALTD
                     RFGPRFSMPLGMVLQGGASFGLMLLDTDSGYGAMWPSFIGLGLGVGMVMAASSEAIVGN
                     APVKDGGVAGGLQATMLQVGGALGTSVLISLISSRVGGTLVGSLTDAGVPAPLAQGLRA
                     AQDAVAMGIAPVTPDMPGTVRAAVIEGAGAAFVAGVHTAALASGVLCLIGAVVSAVFIR
                     RGARPGEIVLPAH"
     misc_feature    7046..7059
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(7192..7638)
                     /locus_tag="ACTEI_RS22410"
     CDS             complement(7192..7638)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="ACTEI_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_122979447.1"
                     /transl_table=11
                     /translation="MTDEAVALMHLAHQLHRSLDRRVQGDFTHPKPPEAQIVALWQIRE
                     RPGITVRELATELQMQPNNASALVTAMVKNGLLTREPDERDRRVVRLRVTGEARDRIDR
                     VQELFTGYLSAALADLAHEERDAVRAALPALARIARHVRDGGRH"
     misc_feature    complement(7591..7607)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     misc_feature    7660..7673
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.15"
                     /tool="antismash"
     misc_feature    complement(7660..7678)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.53"
                     /tool="antismash"
     misc_feature    7663..7675
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.32"
                     /tool="antismash"
     gene            complement(7692..8162)
                     /locus_tag="ACTEI_RS22415"
     CDS             complement(7692..8162)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTEI_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_122979448.1"
                     /transl_table=11
                     /translation="MADDFDDPLVRFGRWALAKVWLGCVLSGGYALGRHYHWPQAFLTC
                     AAMLGAVALALASSFLPIWTRQRPSGIPVVDVGLRVMVWAGLAGSVAALLIALPAVGMV
                     AAALLFTTAARTFRDPFGPLLRRLPITPTVAYRSAARRPASAPDRRPRYAGK"
     gene            complement(8407..9750)
                     /locus_tag="ACTEI_RS22420"
     CDS             complement(8407..9750)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692373.1"
                     /locus_tag="ACTEI_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin reductase family protein"
                     /protein_id="WP_122979449.1"
                     /transl_table=11
                     /translation="MIAVTRARVLTFNRPLRVTRTAIVAFVLCNVLAVQVLWTAAGPAR
                     NLTGTIGRLLGLHLALAMALQLLLVARLPVVDRAYGMDRLTGWHRWTGHAVCWLALAHP
                     AVVLLGFARYDGVSLPAAAAALAGRPPVLLGVIASGLIVVVVALSVRAARRRLSYEAWH
                     AVHLLVYLVVLLGVLHQVYEGAAFRAHPVARGYWWGLWAFAIGALLAGRLVVPMLRNAR
                     HRLRVAAVVAESDDTVSVHITGRALERLPARAGQFFLWRFPGHQRWWQVNPFSLSAAPN
                     GRSLRITAKGVGATSVRLRDLPVGARVYAEGPYGAFTVAHRQRAATVLIAGGIGVTPIR
                     ALLEDPDLTGHVVVLYRVRSARDAVLLGELRALADARRARLHLLAGRSASGYRPFTPDR
                     LLSLVPDITARDVYVCGPDAMTTAVLASLRRLRVPSRQVHAERFRLAG"
     gene            10001..12640
                     /gene="lanKC"
                     /locus_tag="ACTEI_RS22425"
     CDS             10001..12640
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018348543.1"
                     /locus_tag="ACTEI_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_122979450.1"
                     /sec_met_domain="micKC (E-value: 1.3e-260, bitscore: 865.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.2e-12, bitscore: 44.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.2e-06, bitscore:
                     24.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSRYEAFCMASPLFYDALRSATNAGVSFATADRPLPPGWRREEQ
                     DDWLVFSPEALNLPMQGWKIHVSACLDNADRVLDKVWDYCVPRGLEFKFLRSSPALWLR
                     SSKYAPRGYSGKLVTIYPPDDAACERVLTELGELLDGEPGPYILSDLRWGNGPLYVRYG
                     GFAARYCVTDGGQVVLAIADQDGTLVPDRRDPVFYVPPWVPLPDFLAPHLAARNAVTVT
                     DIPYTIERVLHFSNGGGVYLGRDTRTDAEIVLKEGRPHAGLDSTGADAVARIDREYEVL
                     SSLAGVPGVPAVSDRFDLGEHRFLAMEYVDGRPLHRALVRRYPMIDVGAGPADFADYTA
                     WAMNVYEQVETTLRHMHERGVVYGDLHLFNIMIRPDDTVALLDFEVASTTTAAARPGLG
                     NQGFAAPSGTTGVDIDRYALACLRLALFLPMTQLLWLSRAKARDLAGVIAEHFPVPERF
                     LAEAVEIIDPPAKAERDGADHHGRGASTPAAKPWPGLADDWPGQREQLVRGILASASPD
                     RTDRLFPGDIEQFRLNGLGLAYGAAGILHALSVTGAPRQPDLEEWLLQRVKKPARGTML
                     GLYDGLHGVAFALDHLGHRQPALDLLQMCLSDDWQALGLDLMGGLAGIGLNLFHFADRT
                     GDTGLRDLAMRAAQLVGDRLGDVDSVPETSGLENPYAGLFRGSSGPALLLMRAYDETGG
                     PDFLDRAAVALRQDLRRCVVRDNGVMEVDEGWRTMPYLAAGSVGVGIAVDQYLRRRPDD
                     RFTEASAAIHRAAQARMYVQSGLFAGRAGMLLYLAGRATDPRTDPAVADQARRLRWHAM
                     PYADGVAFPGDQLLRLSMDVATGSAGVLLALGAAHHDTPVHLPLIAPATAPRPQSPVST
                     GHGSVGNI"
     gene            12655..12801
                     /locus_tag="ACTEI_RS22430"
     CDS             12655..12801
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013734295.1"
                     /locus_tag="ACTEI_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_122979451.1"
                     /transl_table=11
                     /translation="MALLDLQGLEMSGLETGGGSSSSTGCGVESTASLVVCAASSLSLV
                     TCH"
     CDS_motif       12655..12717
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQGLEMSGLETGGGSS"
                     /locus_tag="ACTEI_RS22430_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12718..12801
                     /prepeptide="core"
                     /locus_tag="ACTEI_RS22430_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="2.30"
                     /molecular_weight="2389.7"
                     /monoisotopic_mass="2388.2"
                     /core_sequence="SSTGCGVESTASLVVCAASSLSLVTCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQGLEMSGLETGGGSS"
                     /leader_location="[12654:12717](+)"
                     /alternative_weights="2407.7"
                     /alternative_weights="2425.7"
                     /alternative_weights="2443.7"
                     /alternative_weights="2461.8"
                     /alternative_weights="2479.8"
                     /alternative_weights="2497.8"
                     /alternative_weights="2515.8"
     gene            12865..14514
                     /locus_tag="ACTEI_RS22435"
     CDS             12865..14514
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009076000.1"
                     /locus_tag="ACTEI_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_122979452.1"
                     /transl_table=11
                     /translation="MLTFGAVVRRSRLWLPLIALTAVTGSLSALALPTVLGRAVDAVLA
                     DGHGGRWLLWATILIAAGVLVDVVDAFAAGACVAGATAWLRERLVRHVLTLDSRGAARF
                     EPGDLVSRVSANAPDAAQAGPSVVLTFTALFAPVGSLVLLALIDWWLAVAFLAASALVA
                     VVLVTFTRRTSRLLAGYQRIQGTMAGRLAESLAGARTIAAAGTVEQERRRILQPLPELR
                     AQGLLSWLALARASAQAAVVGPLVLVAVLGAGGLGLVAGRITAGELFAAGQYAMLGAGL
                     GTLTGVLGRLARARAGVRRLAEVFAVPPMTYGTAGLPPGAGTLRFAGVTVRDGDRRLLD
                     RVDLTVPGGSTVAVVGRSGAGKSTLAALACRLLEPDEGTVLLDGVPLPAVRHEALRAAA
                     GCAFERPVLVGATVGDAIGVGRDAGTVRAAARATEAHRFVSRLPAGYATPLAETPMSGG
                     EAQRLGLARAWPADRLLVLDDATSSLDVVTEMLIHRALAADGERRTRLLVTHRAATAAR
                     ADTVIWLDGGRVRAMAPHRTLWADPAYREVFG"
     gene            14511..16229
                     /locus_tag="ACTEI_RS22440"
     CDS             14511..16229
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018348540.1"
                     /locus_tag="ACTEI_RS22440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_122979453.1"
                     /transl_table=11
                     /translation="MRRELAVCGAALRRRPLLALALWSLPEALPTAVSGLAVARALDAG
                     FLAGRPGTGLAWLATLLVAAAVGAAGARGVYRHLGDLVEPLRDDLVRRVVDGALRRRVA
                     GGAEDGAVARLTHQVEIVRDAFAGLIVIVRSFLVLAVAAVVGLLAVAPAILLIVLPPFL
                     LSLAFFAGTLGMAVSRQRAYVAADERLATASGAVLAGARDLLAQGGEEHGAAMVAAPVR
                     EQAAAERALARVAALRSLTLALGGGVPLLALLAAAPTLVTHGLTAGGIVGGMTYVLRGL
                     QPALGTVVQGLGGSGLRLVVTLGRILDATGPGGAPAAAQRPDPVRPSGTDITLRRVTFA
                     YGPYAEPVLRGFDLDIPPGDHLAVVGPSGIGKSTLAGLVCGLLSPDEGVVLLGGTPVRR
                     LDPAVRVLIPQEAYVFTGTVRENLTYLRPAAGSAEIDAAVTAVGADRLVARLGGPDATV
                     CPDRLSAGERQLLALARAYLADAPVTLLDEATCHLDPAAERQVEEAFAARAGTLVVIAH
                     RVSSALRARRVLVLDGVSAALGTHDELVDRSPLYRELLGRWTAEPLATVHTQPDS"
     gene            complement(16208..16822)
                     /locus_tag="ACTEI_RS22445"
     CDS             complement(16208..16822)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007461895.1"
                     /locus_tag="ACTEI_RS22445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_239082467.1"
                     /transl_table=11
                     /translation="MIRIILAQKGRLIRRALAQMLAQEDDVHVVAEVSAYDEAVTAAVR
                     ERPHVAVLDHALLGPPVAHDLCTDLLKAAPGCRILLIVDRSLPTLAGAELARMTPRVGL
                     LATDASPGQLIEGVRRLSRGQPVLDVDIAVAALSANTTPLTRREREVLLLATEGRPTKE
                     IAAKLCLTDGTVRNYLSRIVAKTGARTLIEAVRRAQESGWV"
     misc_feature    16809..16822
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
     misc_feature    complement(16866..16881)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     misc_feature    complement(16877..16894)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.64"
                     /tool="antismash"
     misc_feature    complement(16883..16899)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     gene            complement(17464..18465)
                     /locus_tag="ACTEI_RS22450"
     CDS             complement(17464..18465)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692376.1"
                     /locus_tag="ACTEI_RS22450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TAXI family TRAP transporter solute-binding
                     subunit"
                     /protein_id="WP_122979454.1"
                     /transl_table=11
                     /translation="MRRILTAATLTALAVATGACGGRQDTAATDTGGDVTCQVDKETRV
                     GIATGNATGVYFALGNAFAEQVNASGGAVRATAAETGASVQNIQQLVAGTYDVAFALAD
                     TAADAVAGTGSFTAKQPVAALARIHTNYTQVIVRKAAGIRDVAGMKGKRVSTGSPKSGT
                     EVIANRVLAAAGLDPARDVSAQKLDLTKTVDGMKDGTIDALFFSGGLPTPGITDLLTTA
                     KDQVEFLDATSLLPNLQKINPVYQQGVIPAATYQRPADVPAIVVPNLLLVRADLDANVA
                     CTLTRTLFDRKTQLEQANGAAREISLDTARRTSPVPLHRGAEKALDNLNAPK"
     misc_feature    complement(18477..18492)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.46"
                     /tool="antismash"
     gene            complement(18537..20546)
                     /locus_tag="ACTEI_RS22455"
     CDS             complement(18537..20546)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014692377.1"
                     /locus_tag="ACTEI_RS22455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TRAP transporter fused permease subunit"
                     /protein_id="WP_122979455.1"
                     /transl_table=11
                     /translation="MGDGRSLGVDAPPAVHYDEEERPARALAGRTALTVAAVAATAGAF
                     TLWQVFRPLAQGSQFYLILFLAGTLPLIFPVYRPRAGRGERPSRLDWLLAALAVAVCLY
                     PVSPAGGGYDGFLDRQALLEPVDVAFGAVLLVLVIEAARRTTGLALPIVCGAFLLYGYY
                     GGRLPQTWPIAHAGLDFAQIVDALYNSGSGFYGTPLDVAATYIVLFTIYGAVLDLSGAS
                     RFFVDLSVAAFRRSRSAAGRTAVAAGFLLGTVSGSGTATAVSVGAVTWPMLRRAGYPPE
                     QAGGMLAAAGVGAILSPPTLGAAAFIVAEYLDVPYLTVLGWAMIPTLLYYLGILLAVEI
                     DVRRFGVRAVEMPATSAWRLLSRFGYHFSSLILIVALLALGESATRAVVYATLLAVLLS
                     FLDRTARLTPARMFGALAAGVRGVLPVVAVCAAAGVITAVTTKTGLGAQLASLLVSGAR
                     AVTDHPGAVLALTVLLAAVALAVLGLAVPVTASFIIGWVIIGPALLGLGVAAPAAAMFV
                     FYYSVLSEVTPPTALAAVGAAAITGGRTMPTMWQALKYALPAFLVPIAFVLTDRGEYLL
                     ARGPAGGVLWTGAAAGLAVLALAVAAGGWVPGVGRATVASRALAGVAGLFLLYLAPLAA
                     GIGAAALAGSALLAAVARWRGAGAPARRAGGVRP"
     misc_feature    20957..20971
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.17"
                     /tool="antismash"
     misc_feature    complement(20991..21004)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    complement(21228..21237)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 ctgaccgccg cggcacgggc cgccggcaga ccgttgacca ggccctcggg atcggtgggg
       61 agcgggtgcc cgtgggtgat catgctgcgg tcgcggtcgt acgccagcga gacggtgacc
      121 ggcgagtgcc agtcgtccag gcgccgggac gcggcaaggt cgatcccctc ctggcggctg
      181 agcacctggt gacagaactc gccgtacgcg tcggtgctca gggcggtgcc gagcccggtg
      241 cgcaggccga gccggctggc cgcgacggcc aggttggcca ccccgccggg gcacgacccc
      301 atgccggacg cccgcacctc ggtgccgggc ccgggcagat cacgcagccc ggtgaagacg
      361 acgtcgagga acaccacccc ggggacgaaa aggtcgagct ggcgcgccat tggccgatct
      421 tacctccgtc ccgatagggc aggtggtaat tgatcactgg atgcggcgca ggtctccatg
      481 cgccgcacgc agggtgtcca cgtggcggtc ggtgcccggc ggccggatct cgtcgagcag
      541 tcgccacgcc tcgtccaaag actgggacag ctcgcggatg cggccggcgt gctggcggcg
      601 cacgtcctcg cggaccttct cgatgcgccg cagccaaccg gcgctgctct ccgggccggg
      661 ccggccctcc gcagcggccg ggaccgcctg cgcggccgga acgggcggac cgggcggcgc
      721 ggccggaacg gcgggcgcga ccggaacggg cggtgacacc ggagcgaccg gcggcgccgg
      781 ttggaggacg tcacgggccg ggacgatggc ggcgatcggg cgaccgccgt cgaccacgac
      841 ggtgatctgg ccggtcaggc cggtgagacg gacgagttgc tggaagcgga gccgggcctc
      901 ggcgacggac agctcgatgc ggcggcggat cggcatggct ggttctccca tgtcccgatg
      961 atgcgcgcgg ggtatgacaa taattcgccg agaacctccc ggacactccg ctaggttcgc
     1021 cggatgaccg attcacttgt ggacctcccc accgccaccg acgtgcgcga cgtggtctcc
     1081 cgggcggcgc aggcgttgcg gacggccggc gaccgggact ggcacctccg agccggcgac
     1141 ctgagctggt cctgctggga gaccgtggaa cacgtcgccg acgacctgtt ctcctatgcc
     1201 ggccagctcg ccgccgagca gccacccagc gaccggtacg tgccgtgggg ctaccggcgc
     1261 tcccgccccg acgcgccggc gctgaccgtc cacgtggacc acgccgaagg caacgcggcg
     1321 ctggtgcagg tgctggaggc cgccggcggc ctgctcgcgg cggtcgtcca ggtcagtccg
     1381 ccgcagcggc gcgggtttca cccgtacggg atcgccgacg cctccggatt cgccgcgatg
     1441 ggcatcaccg aggtcctggt ccacctgtac gacgtggccg ccacactgga cctgcgctgg
     1501 tcccccgatc cgggcgtgtg cgcgcgcgcc ctgcgccgga tcttcgcgga cacaccggcc
     1561 ggcgacgacc cgtgggccac cctgctctgg gccaccggcc gcgtcgggct gcccggccgt
     1621 ccacggcgga ccgagtggcg ctggcacgcc tgacctgcgc caccgccggt cggccttccc
     1681 gcgcgaccga tcccacgcgc cacgagcatc cagagaggca catcgtcatg ggcggggcgc
     1741 acccggcgtg gtcagcgccc ggccacgacc ggcgtccccc ggccggcccg ccggggccgg
     1801 gccaccagca ggaccgccgc gccgaggcag aacaggaccg cgatccagaa gaccgcgacc
     1861 gtgtagccgg gcaccaccag cggggtgagc acgccggccg tggccccgac ctgcaccagc
     1921 gccgtgtacg cgccggcgcc gccacccagc cccgcgcgca gcgtctcgcc gagcagcacc
     1981 atgccgatgc tcgggaagcc ggcggcgaag accgcgtaca gcgcctggga cagcaccagc
     2041 cccggatagc cgccgccggc gatcagggtg aggaaggaca gcacgccgat cccgcacacg
     2101 ccgagcaggg tccaccggct gccgatccgg tcgccgaccg cgctcaccgg ggcgagcacg
     2161 gcgacctcga ccgcgaccgt gaccgcgaac agcgcggaga tcatcggccg gggcgtgccc
     2221 gcgcccagcg cgtagagcgg caggtacacc agccgcaggc tgtccgcggc ccgcatgagc
     2281 agcacggccg cggccgcggc gagcacggcg ggtctcgccg cggcggccgg gtccgtcccg
     2341 ggcggcgggc cgggctcgcc ggccggcgcg ggccggggca ggtgcgcgac cagcgccgcg
     2401 acgacggcca cgccgaccgc gacccggatc gggccgaccg ccgggccgac gctcgcctcc
     2461 ccctgcgcgg ccagcgagaa cagcccgagg ccggccaggt agccgaggac gaagacggtc
     2521 cgcagcgcgg cgacggtgcg cgccgcggag ccgccggccg cggcgccggc caccgcgagg
     2581 tacgacggat agaccacgct catggccatc accaggaccg cggcggggtg gatccgccag
     2641 ccgggaccgt ccgccgccag cacgagcccc ctcttcgcgt acgcggtgcg cccgggcccg
     2701 cccagccgcg ccgacgccca ccggctgctg ccgctggacg aggcgctgcg ccgggtcaac
     2761 accgcggccg ccgtcgctcc ggtgacgccc gtgctggcgt gggcggcgcc ggacgcggac
     2821 ccggtcgtga ccgacgtggc cgcccccacc gcgccgggaa cggccctgaa cgccgccctg
     2881 gcccgcgccg ccatcggctt cctggccggc ccgcaccggt cgaacctgcg cgcctgcacg
     2941 gcgccgcggt gcgtgcggta cttcgtcaag gaacacggcc ggcaggagtt ctgcaaggcg
     3001 tcgtgcagca accgggcccg agccgcgcgg cactaccagc gccaccaccc caccggcacg
     3061 tgaccgcgcc cgcgccaccc gcacgtgacc gcgcccgcgc caccggcacg tgaccgcgcc
     3121 acgccaccgg cacgtgaccg cgcccgcgca ccggcacgtg accgcgcccg cgcccgcgcc
     3181 accggcacgt gaccgcgcca ccggcggcgc cacgccaccg gcacaccgcg gctcagcgcc
     3241 ggtgccgcaa cagcgccgtc atcgcctcgt ccgcgctgtc gccgagcacg gccaggtcca
     3301 cgtcggtgta gatgcgccgc cgggagtcga ccacgcagtg cgcgccgagc atcagccggt
     3361 ccggcgtgat cagcggaacg cccaggtaac tgcgcagccc ggtggtggcc aggaacgggt
     3421 tgaccgcgtg caccgggtcg tcgcggaagt cggccacgcg gtacggctcg ccgtccagca
     3481 cggtccgggt gcacaccgcc cactccgcgg gtgcgccctg cgcgacggcc acccagtcgc
     3541 ccaggccgta cgagccgacg atctgctgca cgtccgcgcc gagcacggtg accagcgaca
     3601 ccggcgcctc gaggagtttc gcgctgcgct cggcgacccg gtccaggtcg gcgcgcagct
     3661 cttgcgcggc caggtcgtac cgggccagct cacgcaggcg ggccgggtcg gcgaggcggt
     3721 cgtggaggga gatgtgcacg ggacctcctg ggggcgtcag tggcggaatc cgccgacgag
     3781 ggtggtgagg tcgccggcca gccgggtgag gtcggccgcg gcctgctggg tggtccgggc
     3841 gccctcggcg gtcgcggcgg ccacctcggc gaccgaggtg accgtacgcg cgaccgcacc
     3901 gctgttggcg gcggcctcgg cgaccgagcg gctcatctcc ccggtggtcg cggtctgctc
     3961 ctcgaccgcc gaggcgatgg tcgtggtgta gtcgccgatc cgctggatga cgtcggtgat
     4021 ctcgccgatc gcggcggtcg ccgaggtgct ggagtcctgg atcgcggtga tccgggcggt
     4081 gatctcctcg gtcgcccggg cggtctgctg ggccagctcc ttgacctcgc cggccaccac
     4141 cgcgaagccc ttgcccagct cgccggcccg ggcggcctcg atcgtcgcgt tcagcgccag
     4201 caggttggtc tgctcggcga tgctggtgat cagccggacc acgtcgccga tctcggcgct
     4261 cgccgagccg agctcggcga cctggtcgtt ggtgcgcgcg gcgacggtca tgccctcgcc
     4321 ggcgacccgg gcggcctcgg cggcgttgga ggcgatctcg gtgatcgagg cgctcatctg
     4381 ctcggcgccg gccgcgatcg actgcacccc ggtgttgacc tgctcgctcg ccgagctggc
     4441 cgtggtggcc cgctcggcca cgtccccggc gccgctctcc agccgcgagc tgatcgcggt
     4501 gagctgctcg gacgcgccgg ccagggtgac cgcggagccg ccgatcgtgg ccagcgtctc
     4561 ccgcagccgc agcaccgcgg cgtccagggc acggctcatc cggcccggct cgtcggccgc
     4621 ggctatcccg gtgcgctggg tgaggtcgcc ggcggcgagc gcctcacaga ccgtggtgac
     4681 ccggcgcagc gcgccgacga tgccgcgggc cacgaccacg cccagcccca gcgcgccgac
     4741 gaggccgacc accaggatca ggatcgagcg caggcggctg gcccgatacc cgtcctcggc
     4801 ctcggcggcg gagtgggcgg cggcggcgcg ttccgcctgg ttgagctcgg tcaggctgtc
     4861 ccggaccgtc tccatcagcg gggtgacccg cgcgccgcgc acctgctgcc actcggcgag
     4921 ccggttggcg cgcgacagcg ggatcatccg ggtgcgcgcg acgtcgacgt actcgcccca
     4981 cgcggcggtc aggctccgca ccgtggcggg cgcgccggcc ggcccggtgg tctggtactc
     5041 ccgcagcgcg gcgtcggcct cggccaggtc ggcggtgaag ttcttctcgt acgccgcctt
     5101 gttcgtgccg tcccggtaga cggcgtgact gaccaggtcc aggcgggact gggtgatcgc
     5161 gttctgcacc cggccgaggg cggcgacgct ggtcaggttg ctcgcgtaga tgtgctgggc
     5221 ggacgcgctg gcgccgctga gcgcggtcag cccgagcacg ccgatcagca gcgcgaccac
     5281 ggaggcgacg ccgatcgcga acatgatctt gaagttgacg ccgagatcgg cccagaaccg
     5341 cttcatcgtg acatcccccg cagccggtgc cgctcctgta tcagaagagt cggcaccggc
     5401 cgcgcggtgc tgagcgcgga tcggcgcgcc cggccggacg ttccccggcg agcgccggac
     5461 ggcgcccgcc cggcacgtgg atcagtgcgc cggcaggacg atctcccccg ggcgggcccc
     5521 gcgccggatg aacaccgcgg agacgaccgc gccgatcagg cagagcacgc cggaggccag
     5581 ggcggcggtg tgcacaccgg cgacgaacgc ggcgccggcg ccctcgatca ccgccgcgcg
     5641 taccgtcccg ggcatgtccg gggtgaccgg cgcgatgccc atcgcgaccg cgtcctgcgc
     5701 cgcccgcagg ccctgggcca gcggcgcggg cacgcccgcg tcggtgagcg aaccgaccag
     5761 cgtgccgccg acccggctgc tgatcagcga gatcagcacc gaggtgccga gcgcgccgcc
     5821 gacctgcagc atggtggcct gcaggccacc ggccacgccg ccgtccttga ccggggcgtt
     5881 gccgacgatc gcctcggacg acgccgccat caccatgccg acgcccaggc ccaggccgat
     5941 gaaggacggc cacatcgccc cgtacccgga gtcggtgtcc agcagcatca ggccgaacga
     6001 ggcgccaccc tgcagcacca tgcccagcgg catcgagaag cgcggcccga accggtcggt
     6061 gagcgcggcg ccgaccggcg aggcgaccac cgaggccagg ctcagcggca gggtgagcac
     6121 gcccgcccag accgggctgt aaccgcggac gttctgcagg tagagcatga tgtagaagat
     6181 cgagccgagc agcgtgaaga agttgaccgc ggtgatcagt gcgccgatgg tgagcgccgg
     6241 gctgcggaac agtcgcatcg gcagcagcgg gtgctccagc cgggtctcga accatccgaa
     6301 gaacaccagg atcagcagcc cggcgagcag cgtgcccagc gtgcggccgg agccccagcc
     6361 ccaggtctcg cccttgacca cgccgaagac caggaccagc aggccggccg cgagcagcgc
     6421 cacgccggcc acgtcgaacc ggtgccggcc ggtggagttg cggctctccg gcagcaccag
     6481 cgcgctgacg atcagggcca gcacgccgac cggggcgttg aggtagaaga ccgactccca
     6541 gctgacgtgc tgcaccagca ggccgccgac gatcgggccg agcgcggtgg agaccgagga
     6601 gaccatcgcc cagatgccga ccgccatgcc gaacctccgc ggcgggaaga ccgcgcgcag
     6661 gatgcccagc gtgttgggca tcaggagggc gccgaagaag ccctgcgcgg cccggaaggc
     6721 gatcacgccg tcgatcgagc cggccagtcc gatcgcgacc gacgagacgg tgaagccggc
     6781 cacgccgatc aggtagtacc ggcgccggcc gaaccggtcg ccgagcttgc cgccgaggat
     6841 cagggcggcg gccagggcga gcaggtaggc gttggtgacc cactgcaact gcgcggtgct
     6901 ggcccgcagg tcgcggccga tctccgggtt ggcgatcgac accacgctgc cgtccagacc
     6961 gaccatgaac aggccgaacg cgacggcggc cagggacagc caggggttgc cgcgccggcc
     7021 cgcgggcggc gcgtgcgcgg gggtgggcac gccggttgcg gtgactgcgg acatgagggg
     7081 actccatctc ggtgcggagg gtgcggtccg gcgggggccg gggtccgttc gatctgcggt
     7141 acggccggtc ggccgccgtc cggtgtcacg cgccccgtgc ggggcgcgtc gtcagtggcg
     7201 cccgccgtcg cggacgtgcc gggcgatccg ggccagggcg ggcagggccg cccgtacggc
     7261 gtcacgctcc tcgtgggcga ggtcggcgag ggccgcggac aggtaaccgg tgaacagctc
     7321 ctgcacccgg tcgatgcggt cgcgggcctc gccggtgacg cgcagccgca ccacccggcg
     7381 gtcccgctcg tccggctccc gggtcagcag gccgttcttg accatcgcgg tgaccagggc
     7441 gctggcgttg ttcggctgca tctgcagctc ggtggcgagc tcccggacgg tgatcccggg
     7501 ccgctcgcgg atctgccaga gcgcgacgat ctgcgcctcc ggcggcttcg ggtgggtgaa
     7561 gtcgccctgc acccgccggt cgaggctgcg gtgcaactgg tgcgccaggt gcatgagggc
     7621 cacggcttcg tcggtcaccc gaccagtatt aggtatgtgg gcataccttt tgcaagttca
     7681 agggtttttg gtcacttccc ggcgtaccgg ggtcgccggt ccggcgcgct ggccggccgc
     7741 cgggctgcgg accggtacgc caccgtgggc gtgatcggca gccggcgcag cagcgggccg
     7801 aacggatccc ggaaggtccg cgcggccgtg gtgaacagca gcgcggcggc caccatgccg
     7861 accgcgggca gcgcgatcag cagcgccgcg accgaaccgg ccaggccggc ccacaccatc
     7921 acgcgcaggc cgacgtcgac gaccgggatg ccgctcgggc gctgccgggt ccagatcggc
     7981 aggaacgagc tggccagcgc cagggcgacg gcgccgagca tggcggcgca ggtcaggaac
     8041 gcctgtggcc agtggtagtg gcggcccagg gcgtaaccac cggagagcac gcaccccagc
     8101 cagaccttgg ccagggccca gcgcccgaac cggaccagcg gatcgtcgaa gtcgtcggcc
     8161 atcgtcgggc tccagccgtg cgcgggtcag cgagcccagt ctaggagcga tcccgccgcc
     8221 tcgggagcag ccgggacacg acccgggcgg cggagcgtca ccggccgggc gacggtgggc
     8281 ccggtcgacg aggcggtgat gccggcggaa cggggcgggt cccgggcgcc gcctccccca
     8341 taccgaggcg gcgcccgggc cctctgcccg gccgcccggg ggcatcgttt ccgggcggcc
     8401 gccgtctcac ccggccagcc ggaaccgttc cgcgtgcacc tggcgggacg gcacccgcag
     8461 gcggcgcagg ctggccagca cggcggtggt catcgcgtcc gggccgcaga cgtacacgtc
     8521 ccgggcggtg atgtcgggga ccagcgacag cagccggtcc ggcgtgaacg gccggtaccc
     8581 gctcgcgctg cggccggcca gcaggtgcag ccgggcccgc cgggcgtccg cgagcgcgcg
     8641 cagctcgccg agcagcaccg cgtcccgcgc gctgcgcacc cggtagagga ccaccacgtg
     8701 accggtcaga tccgggtcct ccagcagcgc ccggatcggg gtgaccccga tcccgccggc
     8761 gatcagcacc gtcgcggcgc gctgccggtg cgccacggtg aacgccccgt acgggccctc
     8821 cgcgtacacc cgcgcgccga ccggcaggtc ccgcagccgg acgctggtgg cgccgacccc
     8881 cttcgcggtg atccgcagcg accggccgtt cggcgccgcc gacagcgaga acgggttcac
     8941 ctgccaccac cgctggtggc cggggaaccg ccagaggaag aactgcccgg cgcgggccgg
     9001 cagccgctcc agcgcccggc cggtgatgtg caccgacacg gtgtcgtccg actcggcgac
     9061 gaccgcggcg acccgcagcc ggtgccgggc gttgcggagc atcgggacca ccaggcggcc
     9121 ggcgagcagg gcgccgatcg cgaacgccca cagcccccac cagtacccac gggcgaccgg
     9181 gtgggcccgg aacgcggcgc cctcgtacac ctggtgcagc acgccgagca ggaccaccag
     9241 gtacaccagc aggtgcacgg cgtgccaggc ctcgtaggac agccggcgcc gcgcggcccg
     9301 gacggacagc gccacgacca ccacgatcag gccggacgcg atcacgccga gcaggaccgg
     9361 cggccgcccg gccagggcgg cggccgcggc cgggagcgag accccgtcgt accgcgcgaa
     9421 gccgagcagc acgaccgccg ggtgggccag ggccagccag cacaccgcgt gtccggtcca
     9481 gcggtgccag ccggtgaggc ggtccatgcc gtacgcccgg tcgaccaccg gcaggcgggc
     9541 caccagcagc agttgcaggg ccatcgccag ggcgaggtgc aggccgagca gccggccgat
     9601 cgtgccggtc aggttccggg ccggaccggc ggccgtccac agcacctgca cggcgagcac
     9661 gttgcacagc acgaacgcca cgatcgcggt acgcgtgacg cgcaggggac ggttgaaggt
     9721 gaggactcgc gcccgggtca cggcgatcat cccggtctcc cctccggcgg gagctgctgt
     9781 tgcccgggtg taccaccgtg gacgccgggt ggttcaccgg tccgcgggcg cggggccgta
     9841 tcccgtcgcc gaaggatcaa acctcaggag tgcaccagtt catgggcgcg tgccatcgcg
     9901 ccggtgtgtg cccctccccg tcaagagatg acaggcgcgg ctggtgccgg ccctctcgtt
     9961 gccggattgt caacggcagg tcaacgagcg agggggatcg atggacagcc ggtacgaggc
    10021 gttctgcatg gcgagtccgc tgttctacga cgcgctccgg tccgccacca acgccggcgt
    10081 ctcgttcgcc accgcggacc gcccgctgcc gcccggctgg cgccgcgagg agcaggacga
    10141 ctggctggtc ttctcgccgg aggcgctgaa cctgccgatg cagggctgga agatccacgt
    10201 ctcggcgtgc ctggacaacg ccgaccgggt gctcgacaag gtctgggact actgcgtgcc
    10261 gcgcgggctg gagttcaagt tcctgcgctc cagcccggcg ctgtggctgc gcagctccaa
    10321 gtacgccccg cgcgggtaca gcggcaagct ggtcaccatc tacccgccgg acgacgcggc
    10381 gtgcgaacgg gtcctgaccg agctgggcga gctgctcgac ggcgagccgg gtccgtacat
    10441 cctgagcgac ctgcgctggg gcaacggccc gctgtacgta cgctacggcg gcttcgccgc
    10501 ccggtactgc gtcaccgacg gcggccaggt ggtgctggcc atcgccgacc aggacggcac
    10561 cctggtgccg gaccggcgcg acccggtgtt ctacgtgccc ccgtgggtgc cgctgccgga
    10621 cttcctggcg ccgcacctgg ccgcccgcaa cgcggtgacc gtcaccgaca tcccgtacac
    10681 catcgagcgg gtgctgcact tctccaacgg tggcggcgtg tatctgggcc gggacacccg
    10741 taccgatgcc gagatcgtcc tcaaggaggg gcgcccgcac gccggcctgg acagcaccgg
    10801 cgccgacgcg gtggcccgga tcgaccggga gtacgaggtg ctcagctcgc tcgccggggt
    10861 gcccggcgtg ccggccgtgt cggaccggtt cgacctgggc gagcaccgct tcctggcgat
    10921 ggagtacgtc gacgggcggc cgctgcaccg ggctctggtg cgccgctacc cgatgatcga
    10981 cgtcggcgcc ggaccggccg acttcgccga ctacaccgcg tgggcgatga acgtgtacga
    11041 gcaggtcgag acgaccctgc ggcacatgca cgagcgcggc gtcgtctacg gcgacctgca
    11101 cctgttcaac atcatgatcc ggccggacga cacggtggcg ctgctggact tcgaggtggc
    11161 ctcgaccacc accgccgccg cccggcccgg gctgggcaac caggggttcg ccgcgccctc
    11221 gggcacgacc ggcgtcgaca tcgaccggta cgcgctggcc tgcctgcgcc tggccctgtt
    11281 cctgccgatg acgcagctgc tctggctgtc ccgggcgaag gcccgggatc tggccggggt
    11341 catcgccgag cacttccccg tgccggaacg cttcctcgcc gaggcggtcg agatcatcga
    11401 cccgccggcg aaggcggagc gggacggcgc ggaccaccac ggccggggcg cgtccacacc
    11461 cgccgcgaag ccgtggcccg ggctggccga cgactggccc ggccagcgcg agcagctggt
    11521 ccggggcatc ctcgccagcg cctcaccgga ccgcaccgac cggctcttcc cgggcgacat
    11581 cgaacagttc cggctcaacg ggctggggct ggcctacggc gccgccggga tcctgcacgc
    11641 cctgtcggtg accggcgccc cacggcagcc ggacctggag gagtggctgc tgcaacgggt
    11701 caagaaaccg gcccggggca ccatgctggg cctgtacgac ggcctgcacg gggtcgcgtt
    11761 cgccctggac cacctcggcc accgccaacc ggccctggac ctgctgcaga tgtgcctcag
    11821 cgacgactgg caggcgctcg gcctggatct gatgggcggg ctcgccggca tcggcctgaa
    11881 cctgttccac ttcgccgacc ggaccggcga caccggcctg cgcgacctgg cgatgcgggc
    11941 ggcgcagctg gtcggcgacc gcctcggtga cgtcgactcg gtcccggaga ccagtggcct
    12001 ggagaacccg tacgccgggt tgttccgcgg ctcgtccggt ccggcgctgc tgctgatgcg
    12061 ggcgtacgac gagaccggcg ggccggactt cctggaccgt gccgccgtgg cgctgcgcca
    12121 ggacctgcgc cgctgcgtgg tgcgcgacaa cggcgtgatg gaggtcgacg agggctggcg
    12181 caccatgccg tacctcgcgg ccggcagcgt cggcgtcggc atcgccgtcg accagtacct
    12241 gcgccgccgc ccggacgacc ggttcaccga ggcgagcgcg gccatccacc gcgccgcgca
    12301 ggcccggatg tacgtgcagt ccggactgtt cgccggccgc gccgggatgc tgctctacct
    12361 ggccggccgg gccacggacc cgcgcaccga cccggccgtg gcggaccagg cccggcggct
    12421 gcgctggcac gcgatgccgt acgccgacgg ggtcgccttc cccggcgacc agctgctgcg
    12481 gctgtccatg gacgtcgcca ccggaagcgc cggggtgctg ctcgccctcg gcgcggcgca
    12541 ccacgacaca ccggtccacc tgccgctgat cgcgccggcc acggcgccgc ggccacagtc
    12601 ccccgtgtcg acgggacacg ggtccgtagg aaacatctag aaggaggaac ctcgatggcg
    12661 cttctcgacc tgcagggcct ggagatgtcc ggtctcgaga ccggcggtgg cagcagcagc
    12721 agcaccggct gcggcgtgga gagcacggcc agcctggtgg tgtgcgcggc cagctcgctg
    12781 agcctcgtca cctgccactg atccacgcca tcggccgcga acggggcaac ccgttcgcgg
    12841 ccgcggtcta tccgggagtg atcgatgctg accttcggcg ccgtcgtccg gcgcagccgg
    12901 ctctggcttc cgctgatcgc gctgaccgcc gtcaccggaa gtctcagcgc cctggccctg
    12961 cccaccgtgc tgggccgggc cgtcgacgcg gtgctcgccg acggccacgg cggccggtgg
    13021 ctgctgtggg ccacgatcct gatcgcggcc ggcgtgctcg tcgacgtcgt ggacgcgttc
    13081 gcggccggcg cgtgcgtcgc cggcgccacc gcctggctgc gggaacggct ggtccgccac
    13141 gtgctcaccc tggattcgcg cggcgccgcc cggttcgagc cgggcgacct ggtcagccgg
    13201 gtcagcgcca acgcgccgga cgccgcccag gccggtccga gcgtcgtgct gacgttcacc
    13261 gcgcttttcg cgccggtcgg cagcctggtg ctgctggcgc tcatcgactg gtggctggcg
    13321 gtggcgttcc tggcggcgtc ggcgctggtg gccgtcgtac tggtgacgtt cacccggcgc
    13381 acctcccggc tgctggccgg ttaccagcgg atccagggca cgatggccgg ccggctggcc
    13441 gagtcgctgg ccggcgcccg gaccatcgcc gcggccggca ccgtggaaca agagcggcgc
    13501 cggatcctgc aacccctgcc ggagctgcgc gcgcagggcc tgctgagctg gctggcgctg
    13561 gcccgggcga gcgcgcaggc ggccgtcgtc ggcccgctcg tgctcgtcgc cgtgctcggc
    13621 gccggcgggc tggggttggt cgccggccgg atcaccgccg gcgaactgtt cgccgccggc
    13681 cagtacgcga tgctcggcgc cgggctgggc acgctcaccg gggtgctggg ccggctggcc
    13741 cgtgcccgcg ccggggtgcg ccgcctcgcc gaggtcttcg ccgtgccccc gatgacctac
    13801 ggcacggccg gcctgccccc gggcgccggc accctgcggt tcgccggggt caccgtccgc
    13861 gacggcgacc gccggctgct cgaccgcgtc gatctgaccg tccccggcgg cagcacggtc
    13921 gccgtggtcg gacgctccgg cgccggcaag tcgacgctgg ccgcgctcgc ctgccgcctg
    13981 ctggaacccg acgagggcac ggtgctgctc gacggggtgc cgctgccggc cgtgcggcac
    14041 gaggcgctcc gggccgccgc gggctgcgcg ttcgagcggc cggtgctggt cggggccacg
    14101 gtcggcgacg ccatcggggt ggggcgggac gccggcaccg tgcgggcggc ggcgcgggcc
    14161 accgaggcgc accgcttcgt cagccggctg cccgccgggt acgcgacccc gctcgccgag
    14221 acgccgatgt ccggcgggga ggcccagcgg ctcgggctgg cccgcgcctg gccggccgac
    14281 cggctgctgg tactcgacga cgccacgtcc agcctggacg tggtgaccga gatgctgatc
    14341 caccgggcgc tcgcggcgga cggggaacgc cgtacccggc tgctcgtcac ccaccgcgcg
    14401 gccaccgcgg cccgggcgga cacggtgatc tggctcgacg gcgggcgggt gcgcgcgatg
    14461 gcgccccatc ggacgttgtg ggccgatccg gcgtaccggg aggtgttcgg atgagacgcg
    14521 agctcgccgt gtgcggcgcc gcgctgcggc gccgcccgct gctggccctg gccctgtggt
    14581 cgctgcccga ggcgctgccg acggccgtct ccggtctcgc cgtggcccgc gccctggacg
    14641 ccggcttcct cgccggccgg cccgggaccg ggctggcgtg gctggcgacg ctgctggtcg
    14701 cggcggcggt cggcgcggcc ggcgcgcgcg gggtgtaccg gcatctcggc gatctcgtcg
    14761 agccgctgcg cgacgacctg gtccgccggg tggtggacgg ggcgctgcgg cgccgggtgg
    14821 ccggtggcgc cgaggacggc gcggtggccc ggctgaccca ccaggtggag atcgtccggg
    14881 acgcgttcgc cgggctcatc gtgatcgtcc gcagcttcct ggtgctggcc gtggccgccg
    14941 tcgtcggact gctcgcggtc gcgccggcga tcctgctgat cgtcctgccg ccgttcctgc
    15001 tcagcctcgc gttcttcgcc ggcacgctgg ggatggccgt cagccgccag cgcgcctacg
    15061 tcgccgcgga cgagcggctg gccaccgcct cgggcgcggt cctggccggc gcccgggacc
    15121 tgctcgcgca gggcggcgag gagcacggcg ccgccatggt cgccgcaccg gtacgggagc
    15181 aggccgcggc ggaacgcgcc ctggcccggg tcgccgcgct gcgcagcctc accctggccc
    15241 tgggcggcgg ggtgccgctg ctggcgctgc tggccgcggc ccccaccctg gtcacgcacg
    15301 gcctcaccgc cggcgggatc gtcggcggca tgacctacgt gctgcgcggg ctccagcccg
    15361 ccctggggac cgtggtgcag gggctgggcg gcagcggcct gcgcctggtg gtgacgctgg
    15421 gccgcatcct cgacgccacc gggcccggcg gcgctcccgc cgcggcgcaa cggcccgatc
    15481 cggtacgacc gtccggcacg gacatcacgc tgcgccgggt gaccttcgcc tacgggccgt
    15541 acgccgaacc cgtgctgcgc ggcttcgacc tggacatccc gcccggcgac cacctggccg
    15601 tggtgggccc cagcgggatc ggcaagtcga cgctggccgg cctggtgtgc gggctgctca
    15661 gcccggacga gggcgtggtg ctgctcggcg ggaccccggt gcgccggctg gacccggcgg
    15721 tccgcgtgct catcccgcag gaggcgtacg tcttcaccgg caccgtacgg gagaacctga
    15781 cctatctgcg cccggccgcc gggagcgccg agatcgacgc cgcggtgacg gcggtgggcg
    15841 ccgaccgcct ggtggcccgg ctgggcgggc cggacgcgac ggtctgcccg gaccggctgt
    15901 cggccgggga gcgccagctt ctcgcgctgg cccgcgccta cctcgccgac gccccggtga
    15961 ccctgctcga cgaggccacg tgccacctcg acccggccgc cgagcggcag gtcgaggagg
    16021 ccttcgcggc gcgcgccgga acgctcgtgg tgatcgccca ccgggtcagc tcggccctgc
    16081 gcgcccggcg ggtgctggtg ctcgacggcg tttcggccgc gctcggcacg cacgacgagc
    16141 tggtggaccg ctcgccgctc taccgcgagc tgctgggccg ctggaccgcc gagccgctgg
    16201 ccacggttca cacccagccg gactcctgag cccggcgcac cgcctcgatc agggtgcggg
    16261 cgccggtctt ggcgacgatc cgggacaggt agttgcgcac ggtgccgtcg gtcaggcaga
    16321 gcttggccgc gatctccttg gtcggccgcc cctcggtggc cagcagcagc acctcgcgct
    16381 cccggcgggt cagcggcgtc gtgttggcgc tcagcgcggc gacggcgatg tcgacgtcga
    16441 gcaccggctg cccccgggac agccggcgca caccttcgat gagctgcccc ggcgacgcgt
    16501 cggtggccag cagacccacc cgcggcgtca tccgggccag ttcggcgccg gccagggtgg
    16561 gcaggctgcg gtccacgatc agcaggatgc ggcagcccgg cgccgccttg agcaggtcgg
    16621 tgcacaggtc gtgcgccacc ggcgggccga gcagcgcgtg gtccagcacc gcgacgtggg
    16681 gcctctcgcg gaccgccgcc gtcaccgcct catcgtaggc gctcacctcg gcgaccacgt
    16741 gcacgtcgtc ctcctgcgcg agcatctgcg ccaacgcccg gcggatcaac ctgcccttct
    16801 gcgcgaggat gatgcggatc acgcgactcc tccgatgaga tacacgccct tctctatagc
    16861 actctgtgac tcgacagtca cgttcttgca acattgccag tcgtacgtgg acgagccgat
    16921 cggcctgtgt ggaccgtcgg tcccgccacc ccggcggtgc ggcaaaggac ggttctgcca
    16981 ccgtacggcc ctgatcgagg gggcgcgggc gcatcacgga aaacctgccc ggccggacgg
    17041 cgggcacatc ccactacggc catcgatcgc tctccgttcg gaggatgcaa ccgcggcgtc
    17101 acaacgagca acatggtgga gccgtccggc cgaccggttc accacccgcc gcagcggggc
    17161 ggacggccgg gagcaccggt cggggccggc tgtcgggacc gcagccggac ccgcaccggc
    17221 gtgggtcgcg tgcacggccg gcaggaggcg gccctacccg gcccgcgcac ccgacgcatc
    17281 gtcaggacca actccacacg ggacgcccga tgtatcgccg gggtcgccct tcctacgccg
    17341 gagcgtccgc gtgccggagc acggagccgg cgaccgcgcg gcagaaagca gcaccgggcc
    17401 ggcgaccgcg cggcagaccg ggaacaccgg gccggccgcg ccgagacggg tgagcgatac
    17461 cggtcacttc ggggcgttca ggttgtcgag ggctttctcg gcgccgcggt gcaggggcac
    17521 cgggctggtg cggcgggcgg tgtccaggct gatctcccgg gccgcgccgt tggcctgttc
    17581 gagctgggtc ttgcggtcga acagggttcg ggtcagggtg caggcgacgt tcgcgtcgag
    17641 gtcggcgcgg accagcagga ggttgggaac gacgatggcc gggacgtcgg cgggccgctg
    17701 gtaggtcgcg gccgggatga cgccctgctg gtacaccggg ttgatcttct gcaggttcgg
    17761 cagcagcgag gtggcatcga ggaactcgac ctgatccttc gcggtcgtca gcagatcggt
    17821 gatgcccggg gtgggtagcc cgccggagaa gaacagcgcg tcgatcgtgc cgtccttcat
    17881 gccgtccacg gtcttggtca ggtcgagttt ctgggcgctg acgtcccggg ccgggtcgag
    17941 gccggcggcg gccagcaccc ggttcgcgat cacctcggtc ccggacttgg gggaaccggt
    18001 ggacacccgc ttgcccttca tgcccgcgac gtcccggatg ccggccgcct tgcggacgat
    18061 cacctgggtg tagttggtgt ggatccgggc cagcgcggcc accggctgct tcgcggtgaa
    18121 actgccggta ccggcgaccg cgtcggcggc ggtgtcggcg agggcgaacg cgacgtcgta
    18181 ggtgcccgcg accagctgct ggatgttctg caccgacgcg ccggtctccg cggcggtggc
    18241 ccgcaccgcg ccgccggacg cgttgacctg ctcggcgaac gcgttgccca gcgcgaagta
    18301 gacgccggtg gcgttgccgg tcgcgatgcc gacccgggtc tccttgtcga cctggcaggt
    18361 gacgtcgccg ccggtgtcgg tggcggcggt gtcctgccgg ccaccgcagg cgccggtggc
    18421 cacggcgagg gcggtgagcg tggcggcggt caggatccgt ctcatgcttc tcctccggga
    18481 atgcgtctca tgcctctcct ggcgggaaag ggcgcctgcg gcgaacggaa cggggctcac
    18541 ggccggacac caccggcgcg ccgggccggt gcgcccgcac cgcgccaccg ggccacggcg
    18601 gccagcagcg cggacccggc cagcgccgcc gccccgatcc cggccgccag cggcgccagg
    18661 tagagcagga acagcccggc gaccccggcc agcgcccggc tcgccactgt ggcccggccg
    18721 acgcccggca cccacccgcc ggccgcgacc gccagagcga gcaccgccag accggccgcc
    18781 gcgccggtcc acagcacccc gccggccggc cccctggcca gcaggtactc cccgcggtcg
    18841 gtgagcacga aggcgatcgg gacgaggaag gcgggcagcg cgtacttcaa cgcctgccac
    18901 atggtcggca tggtccggcc gccggtgatc gcggcggcgc cgaccgcggc gagggcggtc
    18961 ggcggggtga cctcggagag caccgagtag tagaagacga acatggccgc ggcgggagcg
    19021 gccacgccga gcccgagcag cgccggcccg atgatcaccc agccgatgat gaagctggcg
    19081 gtgaccggca ccgcgagccc gagcacggcg agcgccaccg cggccagcag cacggtcagc
    19141 gcgagcaccg cgccggggtg gtcggtgacc gcccgcgcgc cgctgaccag cagcgaggcc
    19201 agctgcgcgc cgagcccggt cttggtggtg accgcggtga tcaccccggc ggcggcgcac
    19261 accgcgacga ccgggagcac cccgcgcacc ccggcggcga gcgcgccgaa catccgggcc
    19321 ggggtcagcc gcgcggtacg gtccaggaag gacagcagca ccgccagcag cgtcgcgtag
    19381 accacggccc gggtggcgct ctcgccgagg gcgagcagcg cgacgatcag gatcagcgac
    19441 gagaagtggt aaccgaaccg gctgagcagc cgccacgcgc tggtcgccgg catctcgacg
    19501 gcgcgcaccc cgaagcggcg tacgtcgatc tcgaccgcca gcaggatgcc caggtagtac
    19561 agcagggtcg ggatcatcgc ccagcccagc acggtgaggt acggcacgtc gaggtattcg
    19621 gcgacgatga acgcggccgc gcccagtgtc ggcggggaca ggatggcgcc caccccggcc
    19681 gcggccagca tccccccggc ctgttccggc gggtatccgg cgcggcgcag catcggccag
    19741 gtgaccgcgc cgacgctgac cgcggtggcg gtgcccgagc cggacacggt gccgagcagg
    19801 aagccggcgg ccaccgcggt gcgcccggcg gcgctgcgcg agcggcggaa cgcggccacc
    19861 gacaggtcga cgaagaagcg gctggcgccg gagaggtcga gcaccgcgcc gtagatggtg
    19921 aacagcacga tgtacgtcgc ggccacgtcg agcggggtgc cgtagaaccc gctgccggag
    19981 ttgtagagcg cgtcgacgat ctgcgcgaag tcgagtccgg cgtgggcgat cggccaggtc
    20041 tgcgggagcc ggccgccgta gtacccgtac aacaggaagg cgccgcagac gatcggcagg
    20101 gcgagcccgg tggtccgccg cgccgcctcg atcaccagca cgagcagcac cgcgccgaac
    20161 gccacgtcga cgggttcgag cagcgcctgc cggtcgagga aaccgtcgta tccgccgccg
    20221 gccgggctga ccgggtagag gcagacggcc acggcgagcg cggccagcag ccagtccagc
    20281 cggctcggcc gctccccgcg accggcccgc ggccggtaca ccgggaagat cagcggcagc
    20341 gtcccggcca ggaagaggat caggtagaac tggctgccct gggccagcgg ccggaacacc
    20401 tgccagagcg tgaacgcccc ggccgtggcg gcgacggcgg cgaccgtgag ggcggtgcgt
    20461 ccggcgagcg cgcgggcggg ccgctcctct tcgtcgtagt ggacggcggg tggggcatcg
    20521 acgccaaggg atcgaccatc gcccatgaat ggacactact acggcgccgc ccgcccgagg
    20581 ccggacgatc atccgatggt gggcgcggca cccaccggcc gcaccgccgg ggcccgggcc
    20641 cgaccgccgc ccggccgccg gagcacgacc ggccgcggcc acccgccgcg aaagaagcgg
    20701 acggccgccg ccgaaccacc ccggcgaacc ggacggccgc cggatcaggc gacctcgcgc
    20761 agccgcgcgg cgacccgctc cggggtggtg tcgctgatcc acgccgccat cgccgactcg
    20821 acgccggcca ggtacttcag cttgccgggc gcccgcagga tgctgaacac ctgcaggtgc
    20881 aggcggaaca ggtcacggcc ggtccggacc ggcgcctggt gcacgccggc gatgtagggc
    20941 agcggctccg ggcccgggaa gtaccggtcc aggcggccca gcacgtccag gtagatccgg
    21001 gccaggtcgt cgcgttccgg gccggtcaac tcggtcaggt cggcggcgtc gcggtgcggg
    21061 gccaggtgca cctcgaccgg ccagcgggcc gcggcgggca cataggcggt ccagtgctcg
    21121 gtcgcggcga cgatccgggt gccggcgcgg cgctccgcgt ccaggatgtc gcggaacagg
    21181 ttgccgccgg tccggtcccg gtgccgggcg gccatctcca gcatccgggc cgccttcggc
    21241 ggcacgaacg ggaaagcgta gatctgcccg tgcgggtgcg gcagggtcac cccgatctcc
    21301 cggccgcggt tctcgaacac gaagacgtgc tcgacgcccg gctgccggcc cagcgcggcg
    21361 gtgcggtcgg cccaggcctc gatcacggtg cgggcccggt gcggcgtcag gctgccgaac
    21421 gacccctgcg ctgccgagga gaagcacacc acctcggtac ggccgccggc cggccgcacc
    21481 ggccacagcg gatcgccgtc gaccaggccc tcggcgcccc cgatgcgcgg ggagaacgcc
    21541 gggaaccggt tctcgaagac gaccacgtcg taaccggcct cggcgatctc ggtggggaac
    21601 ccgccgggga cggtcggcgc cagcgggtcc tggtcggccg gcggcatgaa ggtacggtcg
    21661 ttgcggtgcg acgccagggc gatccactcg ccggtcagcg ggtcgtagcg gacctgggcg
    21721 ccgccgcgca gcacctggtc ggccgggggc agcggccggg tgtcctcggc ctgccgggtg
    21781 gccgcgccgg agacgtacgg ctcggtgtcg tcgtagtaga tgatctcgcg gccgtcggcc
    21841 atccgccgcg acgtccggcg cacccggtgc acccgttccg gctcggtggc gctgccccgg
    21901 ccgaccaccc ggatcgcgtc gatggccagc agctgggagc cggcggcgac cagccggtcg
    21961 cgcgcgtcct cgggcaccgc gaccggggag agggtggcca gcggcagcag gtgcagggtg
    22021 acctcggcgc ctgagcggta cccggcgtcg accaggttga cctgccagcg ggacccgtcc
    22081 cagaaccggt cggtgacggt gaccccgtcg acccgcagct cgccgacgtc accggcccag
    22141 tcgatctgca gcagcgcgtc gtgctccggg tcggcggccc agtccggcag ctgcaggcgg
    22201 tacaccgcgg cgtgctcgtc gaacgccgcc ggggcggggg cggacgcgcg gccgtcgtgc
    22261 ttgccgtacc cggcgggcac cacggcggcg gggcgcagcc gcacggccgg cacgtccccg
    22321 gtccgcgggg cgggcgcggg cgcgaccggc aggtcggcga acccgcgcgc ggccgggtcg
    22381 tagacccgta ccggggcggt gccggtggcc ttgaccgtga tccgcccggc ggcgtcccac
    22441 tgcagttcgt cgtcgctgag caggagccgg cggccccccg cctcgcagac ccagacggct
    22501 tcggccgcct cggccggcag gaggagcacg tcgagccggc cgtcgcgggt ctccacccgg
    22561 accggctcca ggccggggct gatctcccgg accgccgtct cgtcgccgtc gcggaccgcc
    22621 agctcgggcc ggatgccggt
//
